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Demetrios Thomas Braddock, M.D. Ph.D. - Publications

Affiliations: 
Pathology Yale University, New Haven, CT 
Area:
Structural biology, Hematopathology, Genitourinary Pathology
Website:
http://medicine.yale.edu/labs/braddocklab/www/
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13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Hsiao HT, Crichlow GV, Murphy JW, Folta-Stogniew EJ, Lolis EJ, Braddock DT. Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60. Plos One. 15: e0242725. PMID 33253191 DOI: 10.1371/journal.pone.0242725  0.551
2014 Albright RA, Ornstein DL, Cao W, Chang WC, Robert D, Tehan M, Hoyer D, Liu L, Stabach P, Yang G, De La Cruz EM, Braddock DT. Molecular basis of purinergic signal metabolism by ectonucleotide pyrophosphatase/phosphodiesterases 4 and 1 and implications in stroke. The Journal of Biological Chemistry. 289: 3294-306. PMID 24338010 DOI: 10.1074/Jbc.M113.505867  0.522
2012 Albright RA, Chang WC, Robert D, Ornstein DL, Cao W, Liu L, Redick ME, Young JI, De La Cruz EM, Braddock DT. NPP4 is a procoagulant enzyme on the surface of vascular endothelium. Blood. 120: 4432-40. PMID 22995898 DOI: 10.1182/Blood-2012-04-425215  0.5
2011 Saunders LP, Cao W, Chang WC, Albright RA, Braddock DT, De La Cruz EM. Kinetic analysis of autotaxin reveals substrate-specific catalytic pathways and a mechanism for lysophosphatidic acid distribution. The Journal of Biological Chemistry. 286: 30130-41. PMID 21719699 DOI: 10.1074/Jbc.M111.246884  0.502
2011 Ornstein DL, Albright R, Chang WC, Robert D, Cao W, De La Cruz E, Braddock D. Molecular Structure and Biological Activity of NPP-4, An Endothelial Cell Surface Pyrophosphatase/ Phosphodiesterase That Stimulates Platelet Aggregation and Secretion Via Liberation of ADP Upon Hydrolysis of Diadenosine Triphosphate Blood. 118: 701-701. DOI: 10.1182/Blood.V118.21.701.701  0.512
2010 Hsiao HH, Nath A, Lin CY, Folta-Stogniew EJ, Rhoades E, Braddock DT. Quantitative characterization of the interactions among c-myc transcriptional regulators FUSE, FBP, and FIR. Biochemistry. 49: 4620-34. PMID 20420426 DOI: 10.1021/Bi9021445  0.301
2008 Saunders LP, Ouellette A, Bandle R, Chang WC, Zhou H, Misra RN, De La Cruz EM, Braddock DT. Identification of small-molecule inhibitors of autotaxin that inhibit melanoma cell migration and invasion. Molecular Cancer Therapeutics. 7: 3352-62. PMID 18852138 DOI: 10.1158/1535-7163.Mct-08-0463  0.49
2008 Crichlow GV, Zhou H, Hsiao HH, Frederick KB, Debrosse M, Yang Y, Folta-Stogniew EJ, Chung HJ, Fan C, De la Cruz EM, Levens D, Lolis E, Braddock D. Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c-myc inhibition. The Embo Journal. 27: 277-89. PMID 18059478 DOI: 10.1038/Sj.Emboj.7601936  0.323
2004 Huth JR, Yu L, Collins I, Mack J, Mendoza R, Isaac B, Braddock DT, Muchmore SW, Comess KM, Fesik SW, Clore GM, Levens D, Hajduk PJ. NMR-driven discovery of benzoylanthranilic acid inhibitors of far upstream element binding protein binding to the human oncogene c-myc promoter. Journal of Medicinal Chemistry. 47: 4851-7. PMID 15369388 DOI: 10.1021/Jm0497803  0.311
2002 Braddock DT, Louis JM, Baber JL, Levens D, Clore GM. Structure and dynamics of KH domains from FBP bound to single-stranded DNA. Nature. 415: 1051-6. PMID 11875576 DOI: 10.1038/4151051A  0.306
1998 Benzinger TL, Braddock DT, Dominguez SR, Burkoth TS, Miller-Auer H, Subramanian RM, Fless GM, Jones DN, Lynn DG, Meredith SC. Structure-function relationships in side chain lactam cross-linked peptide models of a conserved N-terminal domain of apolipoprotein E. Biochemistry. 37: 13222-9. PMID 9748329 DOI: 10.1021/Bi980482F  0.535
1996 Braddock DT, Mercurius KO, Subramanian RM, Dominguez SR, Davies PF, Meredith SC. Conformationally specific enhancement of receptor-mediated LDL binding and internalization by peptide models of a conserved anionic N-terminal domain of human apolipoprotein E. Biochemistry. 35: 13975-84. PMID 8909295 DOI: 10.1021/Bi960006U  0.543
1994 Luo P, Braddock DT, Subramanian RM, Meredith SC, Lynn DG. Structural and thermodynamic characterization of a bioactive peptide model of apolipoprotein E: side-chain lactam bridges to constrain the conformation. Biochemistry. 33: 12367-77. PMID 7918459 DOI: 10.1021/Bi00207A003  0.535
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