Demetrios Thomas Braddock, M.D. Ph.D. - Publications

Pathology Yale University, New Haven, CT 
Structural biology, Hematopathology, Genitourinary Pathology

20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Albright RA, Stabach P, Cao W, Kavanagh D, Mullen I, Braddock AA, Covo MS, Tehan M, Yang G, Cheng Z, Bouchard K, Yu ZX, Thorn S, Wang X, Folta-Stogniew EJ, ... ... Braddock DT, et al. ENPP1-Fc prevents mortality and vascular calcifications in rodent model of generalized arterial calcification of infancy. Nature Communications. 6: 10006. PMID 26624227 DOI: 10.1038/ncomms10006  0.44
2014 Madiraju AK, Erion DM, Rahimi Y, Zhang XM, Braddock DT, Albright RA, Prigaro BJ, Wood JL, Bhanot S, MacDonald MJ, Jurczak MJ, Camporez JP, Lee HY, Cline GW, Samuel VT, et al. Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase. Nature. 510: 542-6. PMID 24847880 DOI: 10.1038/nature13270  0.44
2014 Albright RA, Ornstein DL, Cao W, Chang WC, Robert D, Tehan M, Hoyer D, Liu L, Stabach P, Yang G, De La Cruz EM, Braddock DT. Molecular basis of purinergic signal metabolism by ectonucleotide pyrophosphatase/phosphodiesterases 4 and 1 and implications in stroke. The Journal of Biological Chemistry. 289: 3294-306. PMID 24338010 DOI: 10.1074/jbc.M113.505867  0.44
2013 Broer PN, Walker ME, Goldberg C, Buonocore S, Braddock DT, Lazova R, Narayan D, Ariyan S. Desmoplastic melanoma: a 12-year experience with sentinel lymph node biopsy. European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. 39: 681-5. PMID 23522951 DOI: 10.1016/j.ejso.2013.02.025  0.44
2012 Albright RA, Chang WC, Robert D, Ornstein DL, Cao W, Liu L, Redick ME, Young JI, De La Cruz EM, Braddock DT. NPP4 is a procoagulant enzyme on the surface of vascular endothelium. Blood. 120: 4432-40. PMID 22995898 DOI: 10.1182/blood-2012-04-425215  0.44
2011 Saunders LP, Cao W, Chang WC, Albright RA, Braddock DT, De La Cruz EM. Kinetic analysis of autotaxin reveals substrate-specific catalytic pathways and a mechanism for lysophosphatidic acid distribution. The Journal of Biological Chemistry. 286: 30130-41. PMID 21719699 DOI: 10.1074/jbc.M111.246884  0.44
2010 Braddock DT. Autotaxin and lipid signaling pathways as anticancer targets. Current Opinion in Investigational Drugs (London, England : 2000). 11: 629-37. PMID 20496257  0.44
2010 Hsiao HH, Nath A, Lin CY, Folta-Stogniew EJ, Rhoades E, Braddock DT. Quantitative characterization of the interactions among c-myc transcriptional regulators FUSE, FBP, and FIR. Biochemistry. 49: 4620-34. PMID 20420426 DOI: 10.1021/bi9021445  0.44
2008 Saunders LP, Ouellette A, Bandle R, Chang WC, Zhou H, Misra RN, De La Cruz EM, Braddock DT. Identification of small-molecule inhibitors of autotaxin that inhibit melanoma cell migration and invasion. Molecular Cancer Therapeutics. 7: 3352-62. PMID 18852138 DOI: 10.1158/1535-7163.MCT-08-0463  0.44
2008 Ornstein DL, Bifulco CB, Braddock DT, Howe JG. Histopathologic and molecular aspects of CD56+ natural killer/ T-cell lymphoma of the testis. International Journal of Surgical Pathology. 16: 291-300. PMID 18573785 DOI: 10.1177/1066896907309687  0.44
2008 Crichlow GV, Zhou H, Hsiao HH, Frederick KB, Debrosse M, Yang Y, Folta-Stogniew EJ, Chung HJ, Fan C, De la Cruz EM, Levens D, Lolis E, Braddock D. Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c-myc inhibition. The Embo Journal. 27: 277-89. PMID 18059478 DOI: 10.1038/sj.emboj.7601936  0.44
2004 Huth JR, Yu L, Collins I, Mack J, Mendoza R, Isaac B, Braddock DT, Muchmore SW, Comess KM, Fesik SW, Clore GM, Levens D, Hajduk PJ. NMR-driven discovery of benzoylanthranilic acid inhibitors of far upstream element binding protein binding to the human oncogene c-myc promoter. Journal of Medicinal Chemistry. 47: 4851-7. PMID 15369388 DOI: 10.1021/jm0497803  0.44
2002 Braddock DT, Baber JL, Levens D, Clore GM. Molecular basis of sequence-specific single-stranded DNA recognition by KH domains: solution structure of a complex between hnRNP K KH3 and single-stranded DNA. The Embo Journal. 21: 3476-85. PMID 12093748 DOI: 10.1093/emboj/cdf352  0.44
2002 Braddock DT, Louis JM, Baber JL, Levens D, Clore GM. Structure and dynamics of KH domains from FBP bound to single-stranded DNA. Nature. 415: 1051-6. PMID 11875576 DOI: 10.1038/4151051a  0.44
2001 Braddock DT, Cai M, Baber JL, Huang Y, Clore GM. Rapid identification of medium- to large-scale interdomain motion in modular proteins using dipolar couplings. Journal of the American Chemical Society. 123: 8634-5. PMID 11525687 DOI: 10.1021/ja016234f  0.44
2000 Caffrey M, Braddock DT, Louis JM, Abu-Asab MA, Kingma D, Liotta L, Tsokos M, Tresser N, Pannell LK, Watts N, Steven AC, Simon MN, Stahl SJ, Wingfield PT, Clore GM. Biophysical characterization of gp41 aggregates suggests a model for the molecular mechanism of HIV-associated neurological damage and dementia. The Journal of Biological Chemistry. 275: 19877-82. PMID 10747981 DOI: 10.1074/jbc.M001036200  0.44
1998 Benzinger TL, Braddock DT, Dominguez SR, Burkoth TS, Miller-Auer H, Subramanian RM, Fless GM, Jones DN, Lynn DG, Meredith SC. Structure-function relationships in side chain lactam cross-linked peptide models of a conserved N-terminal domain of apolipoprotein E. Biochemistry. 37: 13222-9. PMID 9748329 DOI: 10.1021/bi980482f  0.44
1997 Smith Benzinger TL, Braddock DT, Burkoth TS, Auer H, Subramanian R, Jones D, Lynn DG, Meredith SC. A peptide model of one antipode of a switch domain in apolipoprotein e: structure-function relationships Faseb Journal. 11: A1042.  0.44
1996 Braddock DT, Mercurius KO, Subramanian RM, Dominguez SR, Davies PF, Meredith SC. Conformationally specific enhancement of receptor-mediated LDL binding and internalization by peptide models of a conserved anionic N-terminal domain of human apolipoprotein E. Biochemistry. 35: 13975-84. PMID 8909295 DOI: 10.1021/bi960006u  0.44
1994 Luo P, Braddock DT, Subramanian RM, Meredith SC, Lynn DG. Structural and thermodynamic characterization of a bioactive peptide model of apolipoprotein E: side-chain lactam bridges to constrain the conformation. Biochemistry. 33: 12367-77. PMID 7918459 DOI: 10.1021/bi00207a003  0.44
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