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Don M. Coltart - Publications

Affiliations: 
2004-2012 Duke University, Durham, NC 
 2012- University of Houston, Houston, TX, United States 
Website:
http://coltart.chem.uh.edu/members.html
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53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Coltart DM, Uddin N, Knight J, Rastelli E, Soubra-Ghaoui C, Albright T, Wu CH, Wu J. On the Mechanism of the Asymmetric Aldol Addition of Chiral N-Amino Cyclic Carbamate Hydrazones: Evidence of Non-Curtin-Hammett Behavior. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31650641 DOI: 10.1002/Chem.201902388  0.813
2019 Aderibigbe SO, Coltart DM. Synthesis of 1,3-Diketones and β-Keto Thioesters via Soft Enolization. The Journal of Organic Chemistry. 84: 9770-9777. PMID 31333029 DOI: 10.1021/Acs.Joc.9B00397  0.409
2019 Ferguson MW, Gerak CAN, Chow CCT, Rastelli EJ, Elmore KE, Stahl F, Hosseini-Farahabadi S, Baradaran-Heravi A, Coltart DM, Roberge M. The antimalarial drug mefloquine enhances TP53 premature termination codon readthrough by aminoglycoside G418. Plos One. 14: e0216423. PMID 31120902 DOI: 10.1371/Journal.Pone.0216423  0.726
2018 Huynh U, McDonald SL, Lim D, Uddin MN, Wengryniuk SE, Dey S, Coltart DM. Formation, Alkylation and Hydrolysis of Chiral Nonracemic N-Amino Cyclic Carbamate Hydrazones: An Approach to the Enantioselective α-Alkylation of Ketones. The Journal of Organic Chemistry. PMID 30200759 DOI: 10.1021/Acs.Joc.8B00655  0.83
2018 Uddin MN, Tarsis EM, Wu CH, Wu JI, Coltart DM. A Mismatch-Free Strategy for the Diastereoselective α,α-Bisalkylation of Chiral Nonracemic Methyl Ketones. Organic Letters. PMID 29897766 DOI: 10.1021/Acs.Orglett.8B01146  0.829
2018 Rastelli EJ, Bolinger AA, Coltart DM. Stereodivergent Synthesis of β,γ-Fused Bicyclic γ-Lactones via a Multicomponent Ring-Expansion Cascade Chem. 4: 2228-2238. DOI: 10.1016/J.Chempr.2018.08.007  0.831
2017 Alfie RJ, Truong N, Yost JM, Coltart DM. A kinetically controlled direct aldol addition of α-chloro thioesters via soft enolization Tetrahedron Letters. 58: 185-189. DOI: 10.1016/J.Tetlet.2016.11.010  0.8
2017 Huynh U, Uddin MN, Wengryniuk SE, McDonald SL, Coltart DM. On the regioselectivity and diastereoselectivity of ACC hydrazone alkylation Tetrahedron. 73: 432-436. DOI: 10.1016/J.Tet.2016.11.064  0.783
2016 Rastelli EJ, Truong NT, Coltart DM. Asymmetric Induction in Hydroacylation by Cooperative Iminium Ion-Transition-Metal Catalysis. Organic Letters. PMID 27767317 DOI: 10.1021/Acs.Orglett.6B02825  0.778
2016 Rastelli EJ, Coltart DM. Asymmetric Synthesis of (+)-anti- and (-)-syn-Mefloquine Hydrochloride. The Journal of Organic Chemistry. PMID 27657347 DOI: 10.1021/Acs.Joc.6B01476  0.814
2016 Truong N, Sauer SJ, Seraphin-Hatcher C, Coltart DM. Direct carbon-carbon bond formation via reductive soft enolization: a syn-selective Mannich addition of α-iodo thioesters. Organic & Biomolecular Chemistry. PMID 27492274 DOI: 10.1039/C6Ob01244B  0.777
2016 Huynh U, Uddin MN, Wengryniuk SE, McDonald SL, Coltart DM. A simple and efficient approach to the N-amination of oxazolidinones using monochloroamine Tetrahedron Letters. 57: 4799-4802. DOI: 10.1016/J.Tetlet.2016.09.034  0.763
2015 Uteuliyev MM, Nguyen TT, Coltart DM. Diastereoselective addition of Grignard reagents to α-epoxy N-sulfonyl hydrazones. Nature Chemistry. 7: 1024-1027. PMID 26587719 DOI: 10.1038/Nchem.2364  0.52
2015 Rastelli EJ, Coltart DM. A Concise and Highly Enantioselective Total Synthesis of (+)-anti- and (-)-syn-Mefloquine Hydrochloride: Definitive Absolute Stereochemical Assignment of the Mefloquines. Angewandte Chemie (International Ed. in English). PMID 26422780 DOI: 10.1002/Anie.201507304  0.809
2015 Dey S, Wengryniuk SE, Tarsis EM, Robertson BD, Zhou G, Coltart DM. A formal asymmetric synthesis of apratoxin D via advanced-stage asymmetric ACC α,α-bisalkylation of a chiral nonracemic ketone Tetrahedron Letters. DOI: 10.1016/J.Tetlet.2015.04.022  0.798
2015 Garnsey MR, Uteuliyev MM, Coltart DM. Asymmetric synthesis of structural analogues of (+)-clusianone via enantioselective ACC alkylation Tetrahedron Letters. 56: 3183-3185. DOI: 10.1016/J.Tetlet.2015.01.012  0.799
2015 Tarsis EM, Rastelli EJ, Wengryniuk SE, Coltart DM. The apratoxin marine natural products: Isolation, structure determination, and asymmetric total synthesis Tetrahedron. 71: 5029-5044. DOI: 10.1016/J.Tet.2015.05.047  0.756
2013 Knight JD, Coltart DM. Asymmetric anti-aldol addition of achiral ketones via chiral N-amino cyclic carbamate hydrazones. Chemical Communications (Cambridge, England). 49: 7495-7. PMID 23873079 DOI: 10.1039/C3Cc44716B  0.505
2013 Knight JD, Coltart DM. Expanding the scope of the asymmetric anti-aldol addition of chiral N-amino cyclic carbamate hydrazones Tetrahedron Letters. 54: 5470-5472. DOI: 10.1016/J.Tetlet.2013.07.140  0.528
2012 Robertson BD, Wengryniuk SE, Coltart DM. Asymmetric total synthesis of apratoxin D. Organic Letters. 14: 5192-5. PMID 23057680 DOI: 10.1021/Ol302309C  0.794
2011 Hatcher JM, Kohler MC, Coltart DM. Catalytic asymmetric addition of thiols to nitrosoalkenes leading to chiral non-racemic α-sulfenyl ketones. Organic Letters. 13: 3810-3. PMID 21714489 DOI: 10.1021/Ol2012633  0.835
2011 Knight JD, Sauer SJ, Coltart DM. Asymmetric total synthesis of the antimalarial drug (+)-mefloquine hydrochloride via chiral N-amino cyclic carbamate hydrazones. Organic Letters. 13: 3118-21. PMID 21615091 DOI: 10.1021/Ol2010193  0.781
2011 Wengryniuk SE, Lim D, Coltart DM. Regioselective asymmetric α,α-bisalkylation of ketones via complex-induced syn-deprotonation of chiral N-amino cyclic carbamate hydrazones. Journal of the American Chemical Society. 133: 8714-20. PMID 21510644 DOI: 10.1021/Ja202267K  0.806
2011 Garnsey MR, Matous JA, Kwiek JJ, Coltart DM. Asymmetric total synthesis of (+)- and (-)-clusianone and (+)- and (-)-clusianone methyl enol ether via ACC alkylation and evaluation of their anti-HIV activity. Bioorganic & Medicinal Chemistry Letters. 21: 2406-9. PMID 21414776 DOI: 10.1016/J.Bmcl.2011.02.074  0.743
2011 Yost JM, Alfie RJ, Tarsis EM, Chong I, Coltart DM. Direct carbon-carbon bond formation via soft enolization: aldol addition of α-halogenated thioesters. Chemical Communications (Cambridge, England). 47: 571-2. PMID 20963247 DOI: 10.1039/C0Cc02345K  0.792
2010 Krenske EH, Houk KN, Lim D, Wengryniuk SE, Coltart DM. Origins of stereoselectivity in the α-alkylation of chiral hydrazones. The Journal of Organic Chemistry. 75: 8578-84. PMID 21070023 DOI: 10.1021/Jo1019877  0.801
2010 Garnsey MR, Lim D, Yost JM, Coltart DM. Development of a strategy for the asymmetric synthesis of polycyclic polyprenylated acylphloroglucinols via N-amino cyclic carbamate hydrazones: application to the total synthesis of (+)-clusianone. Organic Letters. 12: 5234-7. PMID 20977254 DOI: 10.1021/Ol1022728  0.813
2010 Sauer SJ, Garnsey MR, Coltart DM. Direct carbon-carbon bond formation via reductive soft enolization: a kinetically controlled syn-aldol addition of α-halo thioesters and enolizable aldehydes. Journal of the American Chemical Society. 132: 13997-9. PMID 20849119 DOI: 10.1021/Ja1057407  0.832
2010 Kohler MC, Yost JM, Garnsey MR, Coltart DM. Direct carbon-carbon bond formation via soft enolization: a biomimetic asymmetric Mannich reaction of phenylacetate thioesters. Organic Letters. 12: 3376-9. PMID 20608684 DOI: 10.1021/Ol101152B  0.796
2010 Hatcher JM, Coltart DM. Copper(I)-catalyzed addition of Grignard reagents to in situ-derived N-sulfonyl azoalkenes: an umpolung alkylation procedure applicable to the formation of up to three contiguous quaternary centers. Journal of the American Chemical Society. 132: 4546-7. PMID 20232808 DOI: 10.1021/Ja100932Q  0.747
2010 Coltart D, Sauer S, Garnsey M. Reductive Enolization in Aldol Addition to Enolizable Aldehydes Synfacts. 2010: 1388-1388. DOI: 10.1055/s-0030-1258895  0.817
2009 Zhou G, Lim D, Fang F, Coltart DM. A practical synthesis of b-keto thioesters by direct crossed-claisen coupling of thioesters and N-acylbenzotriazoles Synthesis. 3350-3352. DOI: 10.1055/S-0029-1216971  0.669
2009 Yost JM, Garnsey MR, Kohler MC, Coltart DM. Direct carbon-carbon bond formation via soft enolization of thioesters: An operationally simple mannich addition reaction Synthesis. 56-58. DOI: 10.1055/S-0028-1083278  0.796
2009 Tarsis E, Gromova A, Lim D, Zhou G, Coltart DM. ChemInform Abstract: Overcoming the Limitations of the Morita-Baylis-Hillman Reaction: A Rapid and General Synthesis of α-Alkenyl-β′-hydroxy Thioesters. Cheminform. 40. DOI: 10.1002/chin.200912091  0.82
2008 Tarsis E, Gromova A, Lim D, Zhou G, Coltart DM. Overcoming the limitations of the Morita-Baylis-Hillman reaction: a rapid and general synthesis of alpha-alkenyl-beta'-hydroxy thioesters. Organic Letters. 10: 4819-22. PMID 18844367 DOI: 10.1021/Ol801896Q  0.784
2008 Zhou G, Lim D, Coltart DM. Direct carbon-carbon bond formation via chemoselective soft enolization of thioesters: a remarkably simple and versatile crossed-Claisen reaction applied to the synthesis of LY294002. Organic Letters. 10: 3809-12. PMID 18681454 DOI: 10.1021/Ol801498U  0.651
2008 Lim D, Coltart DM. Simple and efficient asymmetric alpha-alkylation and alpha,alpha-bisalkylation of acyclic ketones by using chiral N-amino cyclic carbamate hydrazones. Angewandte Chemie (International Ed. in English). 47: 5207-10. PMID 18528835 DOI: 10.1002/Anie.200800848  0.501
2008 Lim D, Zhou G, Livanos AE, Fang F, Coltart DM. MgBr2·OEt2-promoted coupling of ketones and activated acyl donors via soft enolization: A practical synthesis of 1,3-diketones Synthesis. 2148-2152. DOI: 10.1055/S-2008-1042947  0.662
2008 Lim D, Coltart DM. ChemInform Abstract: Simple and Efficient Asymmetric α-Alkylation and α,α-Bisalkylation of Acyclic Ketones by Using Chiral N-Amino Cyclic Carbamate Hydrazones. Cheminform. 39. DOI: 10.1002/chin.200841058  0.361
2007 Zhou G, Yost JM, Sauer SJ, Coltart DM. A facile and efficient anti-selective four-component direct aldol addition via chemoselective thioester enolate formation. Organic Letters. 9: 4663-5. PMID 17902688 DOI: 10.1021/Ol702240P  0.805
2007 Lim D, Fang F, Zhou G, Coltart DM. Direct carbon-carbon bond formation via soft enolization: a facile and efficient synthesis of 1,3-diketones. Organic Letters. 9: 4139-42. PMID 17877360 DOI: 10.1021/Ol701599V  0.679
2007 Zhou G, Yost JM, Coltart DM. A direct aldol addition of simple thioesters employing soft enolization Synthesis. 0478-0482. DOI: 10.1055/S-2006-958959  0.815
2006 Yost JM, Zhou G, Coltart DM. A facile and efficient direct aldol addition of simple thioesters. Organic Letters. 8: 1503-6. PMID 16562927 DOI: 10.1021/Ol060413Q  0.796
2006 Coltart D, Yost J, Zhou G. Efficient Aldol Addition of Simple Thioesters Synfacts. 2006: 0591-0591. DOI: 10.1055/s-2006-934524  0.75
2003 Clive DL, Hisaindee S, Coltart DM. Derivatized amino acids relevant to native peptide synthesis by chemical ligation and acyl transfer. The Journal of Organic Chemistry. 68: 9247-54. PMID 14629143 DOI: 10.1021/Jo030192R  0.657
2003 Coltart DM, Danishefsky SJ. Novel synthetic approach to the 8,10-dimethyl anti-syn-anti-perhydrophenanthrene skeleton. Organic Letters. 5: 1289-92. PMID 12688741 DOI: 10.1021/Ol034213F  0.544
2003 Keding SJ, Atsushi E, Biswas K, Zatorski A, Coltart DM, Danishefsky SJ. Hydroxynorleucine as a glycosyl acceptor is an efficient means for introducing amino acid functionality into complex carbohydrates Tetrahedron Letters. 44: 3413-3416. DOI: 10.1016/S0040-4039(03)00517-3  0.443
2002 Ragupathi G, Coltart DM, Williams LJ, Koide F, Kagan E, Allen J, Harris C, Glunz PW, Livingston PO, Danishefsky SJ. On the power of chemical synthesis: immunological evaluation of models for multiantigenic carbohydrate-based cancer vaccines. Proceedings of the National Academy of Sciences of the United States of America. 99: 13699-704. PMID 12359877 DOI: 10.1073/Pnas.202427599  0.42
2002 Coltart DM, Royyuru AK, Williams LJ, Glunz PW, Sames D, Kuduk SD, Schwarz JB, Chen XT, Danishefsky SJ, Live DH. Principles of mucin architecture: structural studies on synthetic glycopeptides bearing clustered mono-, di-, tri-, and hexasaccharide glycodomains. Journal of the American Chemical Society. 124: 9833-44. PMID 12175243 DOI: 10.1021/Ja020208F  0.639
2002 Ragupathi G, Deshpande PP, Coltart DM, Kim HM, Williams LJ, Danishefsky SJ, Livingston PO. Constructing an adenocarcinoma vaccine: immunization of mice with synthetic KH-1 nonasaccharide stimulates anti-KH-1 and anti-Le(y) antibodies. International Journal of Cancer. Journal International Du Cancer. 99: 207-12. PMID 11979435 DOI: 10.1002/Ijc.10305  0.431
2002 Biswas K, Coltart DM, Danishefsky SJ. Construction of carbohydrate-based antitumor vaccines: Synthesis of glycosyl amino acids by olefin cross-metathesis Tetrahedron Letters. 43: 6107-6110. DOI: 10.1016/S0040-4039(02)01336-9  0.377
1999 Clive DL, Coltart DM, Zhou Y. Synthesis of the Angiotensin-Converting Enzyme Inhibitors (-)-A58365A and (-)-A58365B from a Common Intermediate. The Journal of Organic Chemistry. 64: 1447-1454. PMID 11674202 DOI: 10.1021/Jo9822941  0.617
1996 Coltart DM, Charlton JL. The asymmetric synthesis of aryltetralin lignans: (-)-isolariciresinol dimethyl ether and (-)-deoxysikkimotoxin Canadian Journal of Chemistry. 74: 88-94. DOI: 10.1139/V96-011  0.44
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