George Witman - Publications

Affiliations: 
Cell biology UMASS Medical School, Worcester, MA, United States 

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Braschi B, Omran H, Witman GB, Pazour GJ, Pfister KK, Bruford EA, King SM. Consensus nomenclature for dyneins and associated assembly factors. The Journal of Cell Biology. 221. PMID 35006274 DOI: 10.1083/jcb.202109014  0.625
2019 Picariello T, Brown JM, Hou Y, Swank G, Cochran DA, King OD, Lechtreck K, Pazour GJ, Witman GB. A global analysis of IFT-A function reveals specialization for transport of membrane-associated proteins into cilia. Journal of Cell Science. PMID 30659111 DOI: 10.1242/jcs.220749  0.669
2018 Kubo T, Hou Y, Cochran DA, Witman GB, Oda T. A microtubule-dynein tethering complex regulates the axonemal inner dynein(I1). Molecular Biology of the Cell. PMID 29540525 DOI: 10.1091/mbc.E17-11-0689  0.305
2017 Hou Y, Witman GB. The N-terminus of IFT46 mediates intraflagellar transport of outer arm dynein and its cargo-adaptor ODA16. Molecular Biology of the Cell. PMID 28701346 DOI: 10.1091/mbc.E17-03-0172  0.353
2017 Brown JM, Mosley M, Montes-Berrueta D, Hou Y, Yang F, Scarbrough C, Witman GB, Wirschell M. Characterization of a new oda3 allele, oda3-6, defective in assembly of the outer dynein arm-docking complex in Chlamydomonas reinhardtii. Plos One. 12: e0173842. PMID 28291812 DOI: 10.1371/journal.pone.0173842  0.338
2015 San Agustin JT, Pazour GJ, Witman GB. Intraflagellar transport is essential for mammalian spermiogenesis but is absent in mature sperm. Molecular Biology of the Cell. 26: 4358-72. PMID 26424803 DOI: 10.1091/mbc.E15-08-0578  0.647
2015 Kubo T, Hirono M, Aikawa T, Kamiya R, Witman GB. Reduced tubulin polyglutamylation suppresses flagellar shortness in Chlamydomonas. Molecular Biology of the Cell. 26: 2810-22. PMID 26085508 DOI: 10.1091/mbc.E15-03-0182  0.337
2015 Damerla RR, Cui C, Gabriel GC, Liu X, Craige B, Gibbs BC, Francis R, Li Y, Chatterjee B, San Agustin JT, Eguether T, Subramanian R, Witman GB, Michaud JL, Pazour GJ, et al. Novel Jbts17 mutant mouse model of Joubert syndrome with cilia transition zone defects and cerebellar and other ciliopathy related anomalies. Human Molecular Genetics. 24: 3994-4005. PMID 25877302 DOI: 10.1093/Hmg/Ddv137  0.767
2014 Awata J, Takada S, Standley C, Lechtreck KF, Bellvé KD, Pazour GJ, Fogarty KE, Witman GB. NPHP4 controls ciliary trafficking of membrane proteins and large soluble proteins at the transition zone. Journal of Cell Science. 127: 4714-27. PMID 25150219 DOI: 10.1242/jcs.155275  0.634
2014 Awata J, Takada S, Standley C, Lechtreck KF, Bellvé KD, Pazour GJ, Fogarty KE, Witman GB. NPHP4 controls ciliary trafficking of membrane proteins and large soluble proteins at the transition zone Journal of Cell Science. 127: 4714-4727. DOI: 10.1242/jcs.155275  0.633
2013 Lechtreck KF, Brown JM, Sampaio JL, Craft JM, Shevchenko A, Evans JE, Witman GB. Cycling of the signaling protein phospholipase D through cilia requires the BBSome only for the export phase. The Journal of Cell Biology. 201: 249-61. PMID 23589493 DOI: 10.1083/jcb.201207139  0.35
2013 Ludington WB, Wemmer KA, Lechtreck KF, Witman GB, Marshall WF. Avalanche-like behavior in ciliary import. Proceedings of the National Academy of Sciences of the United States of America. 110: 3925-30. PMID 23431147 DOI: 10.1073/Pnas.1217354110  0.517
2012 Engel BD, Ishikawa H, Wemmer KA, Geimer S, Wakabayashi K, Hirono M, Craige B, Pazour GJ, Witman GB, Kamiya R, Marshall WF. The role of retrograde intraflagellar transport in flagellar assembly, maintenance, and function. The Journal of Cell Biology. 199: 151-67. PMID 23027906 DOI: 10.1083/Jcb.201206068  0.715
2011 Hom EF, Witman GB, Harris EH, Dutcher SK, Kamiya R, Mitchell DR, Pazour GJ, Porter ME, Sale WS, Wirschell M, Yagi T, King SM. A unified taxonomy for ciliary dyneins. Cytoskeleton (Hoboken, N.J.). 68: 555-65. PMID 21953912 DOI: 10.1002/Cm.20533  0.663
2011 Yang Y, Cochran DA, Gargano MD, King I, Samhat NK, Burger BP, Sabourin KR, Hou Y, Awata J, Parry DA, Marshall WF, Witman GB, Lu X. Regulation of flagellar motility by the conserved flagellar protein CG34110/Ccdc135/FAP50. Molecular Biology of the Cell. 22: 976-87. PMID 21289096 DOI: 10.1091/Mbc.E10-04-0331  0.584
2010 Craige B, Tsao CC, Diener DR, Hou Y, Lechtreck KF, Rosenbaum JL, Witman GB. CEP290 tethers flagellar transition zone microtubules to the membrane and regulates flagellar protein content. The Journal of Cell Biology. 190: 927-40. PMID 20819941 DOI: 10.1083/Jcb.201006105  0.601
2009 Engel BD, Lechtreck KF, Sakai T, Ikebe M, Witman GB, Marshall WF. Total internal reflection fluorescence (TIRF) microscopy of Chlamydomonas flagella. Methods in Cell Biology. 93: 157-77. PMID 20409817 DOI: 10.1016/S0091-679X(08)93009-0  0.489
2009 Lechtreck KF, Johnson EC, Sakai T, Cochran D, Ballif BA, Rush J, Pazour GJ, Ikebe M, Witman GB. The Chlamydomonas reinhardtii BBSome is an IFT cargo required for export of specific signaling proteins from flagella. The Journal of Cell Biology. 187: 1117-32. PMID 20038682 DOI: 10.1083/jcb.200909183  0.667
2009 Lechtreck KF, Luro S, Awata J, Witman GB. HA-tagging of putative flagellar proteins in Chlamydomonas reinhardtii identifies a novel protein of intraflagellar transport complex B. Cell Motility and the Cytoskeleton. 66: 469-82. PMID 19382199 DOI: 10.1002/cm.20369  0.39
2008 Lechtreck KF, Delmotte P, Robinson ML, Sanderson MJ, Witman GB. Mutations in Hydin impair ciliary motility in mice. The Journal of Cell Biology. 180: 633-43. PMID 18250199 DOI: 10.1083/Jcb.200710162  0.332
2007 Huang K, Diener DR, Mitchell A, Pazour GJ, Witman GB, Rosenbaum JL. Function and dynamics of PKD2 in Chlamydomonas reinhardtii flagella. The Journal of Cell Biology. 179: 501-14. PMID 17984324 DOI: 10.1083/Jcb.200704069  0.71
2007 Merchant SS, Prochnik SE, Vallon O, Harris EH, Karpowicz SJ, Witman GB, Terry A, Salamov A, Fritz-Laylin LK, Maréchal-Drouard L, Marshall WF, Qu LH, Nelson DR, Sanderfoot AA, Spalding MH, et al. The Chlamydomonas genome reveals the evolution of key animal and plant functions. Science (New York, N.Y.). 318: 245-50. PMID 17932292 DOI: 10.1126/Science.1143609  0.73
2007 Hou Y, Qin H, Follit JA, Pazour GJ, Rosenbaum JL, Witman GB. Functional analysis of an individual IFT protein: IFT46 is required for transport of outer dynein arms into flagella. The Journal of Cell Biology. 176: 653-65. PMID 17312020 DOI: 10.1083/Jcb.200608041  0.729
2007 Lechtreck KF, Witman GB. Chlamydomonas reinhardtii hydin is a central pair protein required for flagellar motility. The Journal of Cell Biology. 176: 473-82. PMID 17296796 DOI: 10.1083/jcb.200611115  0.331
2006 Yang P, Diener DR, Yang C, Kohno T, Pazour GJ, Dienes JM, Agrin NS, King SM, Sale WS, Kamiya R, Rosenbaum JL, Witman GB. Radial spoke proteins of Chlamydomonas flagella. Journal of Cell Science. 119: 1165-74. PMID 16507594 DOI: 10.1242/Jcs.02811  0.712
2006 Pazour GJ, Agrin N, Walker BL, Witman GB. Identification of predicted human outer dynein arm genes: candidates for primary ciliary dyskinesia genes. Journal of Medical Genetics. 43: 62-73. PMID 15937072 DOI: 10.1136/jmg.2005.033001  0.584
2005 Pfister KK, Fisher EM, Gibbons IR, Hays TS, Holzbaur EL, McIntosh JR, Porter ME, Schroer TA, Vaughan KT, Witman GB, King SM, Vallee RB. Cytoplasmic dynein nomenclature. The Journal of Cell Biology. 171: 411-3. PMID 16260502 DOI: 10.1083/Jcb.200508078  0.301
2005 DiBella LM, Gorbatyuk O, Sakato M, Wakabayashi K, Patel-King RS, Pazour GJ, Witman GB, King SM. Differential light chain assembly influences outer arm dynein motor function. Molecular Biology of the Cell. 16: 5661-74. PMID 16195342 DOI: 10.1091/mbc.E05-08-0732  0.627
2005 Pazour GJ, Agrin N, Leszyk J, Witman GB. Proteomic analysis of a eukaryotic cilium. The Journal of Cell Biology. 170: 103-13. PMID 15998802 DOI: 10.1083/jcb.200504008  0.621
2004 Jurczyk A, Gromley A, Redick S, San Agustin J, Witman G, Pazour GJ, Peters DJ, Doxsey S. Pericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assembly. The Journal of Cell Biology. 166: 637-43. PMID 15337773 DOI: 10.1083/Jcb.200405023  0.648
2004 Hou Y, Pazour GJ, Witman GB. A dynein light intermediate chain, D1bLIC, is required for retrograde intraflagellar transport. Molecular Biology of the Cell. 15: 4382-94. PMID 15269286 DOI: 10.1091/mbc.E04-05-0377  0.648
2004 Wirschell M, Pazour G, Yoda A, Hirono M, Kamiya R, Witman GB. Oda5p, a novel axonemal protein required for assembly of the outer dynein arm and an associated adenylate kinase. Molecular Biology of the Cell. 15: 2729-41. PMID 15064350 DOI: 10.1091/mbc.E03-11-0820  0.632
2003 Witman GB. Cell motility: deaf Drosophila keep the beat. Current Biology : Cb. 13: R796-8. PMID 14561418  0.35
2003 Casey DM, Inaba K, Pazour GJ, Takada S, Wakabayashi K, Wilkerson CG, Kamiya R, Witman GB. DC3, the 21-kDa subunit of the outer dynein arm-docking complex (ODA-DC), is a novel EF-hand protein important for assembly of both the outer arm and the ODA-DC. Molecular Biology of the Cell. 14: 3650-63. PMID 12972554 DOI: 10.1091/mbc.E03-01-0057  0.562
2003 Pazour GJ, Witman GB. The vertebrate primary cilium is a sensory organelle. Current Opinion in Cell Biology. 15: 105-10. PMID 12517711  0.539
2002 Rosenbaum JL, Witman GB. Intraflagellar transport. Nature Reviews. Molecular Cell Biology. 3: 813-25. PMID 12415299 DOI: 10.1038/nrm952  0.567
2002 Pazour GJ, San Agustin JT, Follit JA, Rosenbaum JL, Witman GB. Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease. Current Biology : Cb. 12: R378-80. PMID 12062067 DOI: 10.1016/S0960-9822(02)00877-1  0.628
2002 Pazour GJ, Baker SA, Deane JA, Cole DG, Dickert BL, Rosenbaum JL, Witman GB, Besharse JC. The intraflagellar transport protein, IFT88, is essential for vertebrate photoreceptor assembly and maintenance. The Journal of Cell Biology. 157: 103-13. PMID 11916979 DOI: 10.1083/Jcb.200107108  0.768
2002 Takada S, Wilkerson CG, Wakabayashi K, Kamiya R, Witman GB. The outer dynein arm-docking complex: composition and characterization of a subunit (oda1) necessary for outer arm assembly. Molecular Biology of the Cell. 13: 1015-29. PMID 11907279 DOI: 10.1091/mbc.01-04-0201  0.311
2000 Pazour GJ, Witman GB. Forward and reverse genetic analysis of microtubule motors in Chlamydomonas. Methods (San Diego, Calif.). 22: 285-98. PMID 11133235 DOI: 10.1006/meth.2000.1081  0.581
2000 Pazour GJ, Dickert BL, Vucica Y, Seeley ES, Rosenbaum JL, Witman GB, Cole DG. Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella. The Journal of Cell Biology. 151: 709-18. PMID 11062270 DOI: 10.1083/Jcb.151.3.709  0.771
1999 Pazour GJ, Koutoulis A, Benashski SE, Dickert BL, Sheng H, Patel-King RS, King SM, Witman GB. LC2, the chlamydomonas homologue of the t complex-encoded protein Tctex2, is essential for outer dynein arm assembly. Molecular Biology of the Cell. 10: 3507-20. PMID 10512883  0.614
1999 Horst CJ, Fishkind DJ, Pazour GJ, Witman GB. An insertional mutant of Chlamydomonas reinhardtii with defective microtubule positioning Cell Motility and the Cytoskeleton. 44: 143-154. PMID 10506749 DOI: 10.1002/(SICI)1097-0169(199910)44:2<143::AID-CM6>3.0.CO;2-3  0.612
1999 Pazour GJ, Dickert BL, Witman GB. The DHC1b (DHC2) isoform of cytoplasmic dynein is required for flagellar assembly. The Journal of Cell Biology. 144: 473-81. PMID 9971742  0.615
1998 Pazour GJ, Wilkerson CG, Witman GB. A dynein light chain is essential for the retrograde particle movement of intraflagellar transport (IFT). The Journal of Cell Biology. 141: 979-92. PMID 9585416  0.63
1997 Koutoulis A, Pazour GJ, Wilkerson CG, Inaba K, Sheng H, Takada S, Witman GB. The Chlamydomonas reinhardtii ODA3 gene encodes a protein of the outer dynein arm docking complex. The Journal of Cell Biology. 137: 1069-80. PMID 9166407  0.643
1995 Wilkerson CG, King SM, Koutoulis A, Pazour GJ, Witman GB. The 78,000 M(r) intermediate chain of Chlamydomonas outer arm dynein isa WD-repeat protein required for arm assembly. The Journal of Cell Biology. 129: 169-78. PMID 7698982  0.57
1995 Pazour GJ, Sineshchekov OA, Witman GB. Mutational analysis of the phototransduction pathway of Chlamydomonas reinhardtii. The Journal of Cell Biology. 131: 427-40. PMID 7593169  0.573
1995 Moss AG, Pazour GJ, Witman GB. Assay of Chlamydomonas phototaxis. Methods in Cell Biology. 47: 281-7. PMID 7476500  0.476
1993 Horst CJ, Witman GB. ptx1, a nonphototactic mutant of Chlamydomonas, lacks control of flagellar dominance. The Journal of Cell Biology. 120: 733-41. PMID 8425899 DOI: 10.1083/JCB.120.3.733  0.317
1982 Remillard SP, Witman GB. Synthesis, transport, and utilization of specific flagellar proteins during flagellar regeneration in Chlamydomonas. The Journal of Cell Biology. 93: 615-31. PMID 7118994 DOI: 10.1083/JCB.93.3.615  0.303
1978 Witman GB, Plummer J, Sander G. Chlamydomonas flagellar mutants lacking radial spokes and central tubules. Structure, composition, and function of specific axonemal components. The Journal of Cell Biology. 76: 729-47. PMID 632325 DOI: 10.1083/JCB.76.3.729  0.352
1974 Dentler WL, Granett S, Witman GB, Rosenbaum JL. Directionality of brain microtubule assembly in vitro Proceedings of the National Academy of Sciences of the United States of America. 71: 1710-1714. PMID 4134974 DOI: 10.1073/Pnas.71.5.1710  0.506
1972 Witman GB, Carlson K, Rosenbaum JL. Chlamydomonas flagella. II. The distribution of tubulins 1 and 2 in the outer doublet microtubules Journal of Cell Biology. 54: 540-555. PMID 5044758 DOI: 10.1083/Jcb.54.3.540  0.534
1972 Witman GB, Carlson K, Berliner J, Rosenbaum JL. Chlamydomonas flagella. I. Isolation and electrophoretic analysis of microtubules, matrix, membranes, and mastigonemes Journal of Cell Biology. 54: 507-539. PMID 4558009 DOI: 10.1083/Jcb.54.3.507  0.565
1971 Olmsted JB, Witman GB, Carlson K, Rosenbaum JL. Comparison of the microtubule proteins of neuroblastoma cells, brain, and Chlamydomonas flagella Proceedings of the National Academy of Sciences of the United States of America. 68: 2273-2277. PMID 5289385 DOI: 10.1073/Pnas.68.9.2273  0.735
Show low-probability matches.