Leslie M. Hicks - Publications

Chemistry University of North Carolina, Chapel Hill, Chapel Hill, NC 
mass spectrometric approaches for protein characterization

66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ford MM, Smythers AL, McConnell EW, Lowery SC, Kolling DRJ, Hicks LM. Inhibition of TOR in Leads to Rapid Cysteine Oxidation Reflecting Sustained Physiological Changes. Cells. 8. PMID 31569396 DOI: 10.3390/cells8101171  0.52
2019 Moyer TB, Heil LR, Kirkpatrick CL, Goldfarb D, Lefever WA, Parsley NC, Wommack AJ, Hicks LM. PepSAVI-MS Reveals a Proline-rich Antimicrobial Peptide in . Journal of Natural Products. PMID 31557021 DOI: 10.1021/acs.jnatprod.9b00352  0.36
2019 Parsley NC, Sadecki PW, Hartmann CJ, Hicks LM. "" No More: An Analysis of Antibacterial Cyclotides. Journal of Natural Products. PMID 31464123 DOI: 10.1021/acs.jnatprod.9b00359  0.36
2019 Berg P, McConnell EW, Hicks LM, Popescu SC, Popescu GV. Evaluation of linear models and missing value imputation for the analysis of peptide-centric proteomics. Bmc Bioinformatics. 20: 102. PMID 30871482 DOI: 10.1186/s12859-019-2619-6  0.52
2019 Biswal AK, Mcconnell EW, Werth EG, Lo SF, Yu SM, Hicks L, Jones AM. The Nucleotide-dependent Interactome of Rice Heterotrimeric G-Protein α -Subunit. Proteomics. e1800385. PMID 30866160 DOI: 10.1002/pmic.201800385  0.52
2019 Fleming SR, Bartges TE, Vinogradov AA, Kirkpatrick CL, Goto Y, Suga H, Hicks LM, Bowers AA. Flexizyme-enabled benchtop biosynthesis of thiopeptides. Journal of the American Chemical Society. PMID 30602112 DOI: 10.1021/jacs.8b11521  0.36
2018 McConnell EW, Berg P, Westlake TJ, Wilson KM, Popescu GV, Hicks LM, Popescu SC. Proteome-wide analysis of cysteine reactivity during effector-triggered immunity. Plant Physiology. PMID 30510037 DOI: 10.1104/pp.18.01194  0.52
2018 Al-Barakati HJ, McConnell EW, Hicks LM, Poole LB, Newman RH, Kc DB. SVM-SulfoSite: A support vector machine based predictor for sulfenylation sites. Scientific Reports. 8: 11288. PMID 30050050 DOI: 10.1038/s41598-018-29126-x  0.52
2018 Werth EG, McConnell EW, Couso Lianez I, Perrine Z, Crespo JL, Umen JG, Hicks LM. Investigating the effect of target of rapamycin kinase inhibition on the Chlamydomonas reinhardtii phosphoproteome: from known homologs to new targets. The New Phytologist. PMID 30040123 DOI: 10.1111/nph.15339  0.52
2018 Kirkpatrick CL, Parsley NC, Bartges TE, Wing CE, Kommineni S, Kristich CJ, Salzman NH, Patrie SM, Hicks LM. Exploring bioactive peptides from bacterial secretomes using PepSAVI-MS: identification and characterization of Bac-21 from Enterococcus faecalis pPD1. Microbial Biotechnology. PMID 30014612 DOI: 10.1111/1751-7915.13299  0.36
2018 Kirkpatrick CL, Parsley NC, Bartges TE, Cooke ME, Evans WS, Heil LR, Smith TJ, Hicks LM. Correction to: Fungal Secretome Analysis Via PepSAVI-MS: Identification of the Bioactive Peptide KP4 from Ustilago maydis. Journal of the American Society For Mass Spectrometry. PMID 29998360 DOI: 10.1007/s13361-018-2016-9  0.36
2018 Parsley NC, Kirkpatrick CL, Crittenden CM, Rad JG, Hoskin DW, Brodbelt JS, Hicks LM. PepSAVI-MS reveals anticancer and antifungal cycloviolacins in Viola odorata. Phytochemistry. 152: 61-70. PMID 29734037 DOI: 10.1016/j.phytochem.2018.04.014  0.36
2018 McConnell EW, Werth EG, Hicks LM. The phosphorylated redox proteome of Chlamydomonas reinhardtii: Revealing novel means for regulation of protein structure and function. Redox Biology. 17: 35-46. PMID 29673699 DOI: 10.1016/j.redox.2018.04.003  0.52
2018 Kirkpatrick CL, Parsley NC, Bartges TE, Cooke ME, Evans WS, Heil LR, Smith TJ, Hicks LM. Fungal Secretome Analysis via PepSAVI-MS: Identification of the Bioactive Peptide KP4 from Ustilago maydis. Journal of the American Society For Mass Spectrometry. PMID 29404970 DOI: 10.1007/s13361-017-1880-z  0.36
2018 Li B, Tunc-Ozdemir M, Urano D, Jia H, Werth EG, Mowrey DD, Hicks LM, Dokholyan NV, Torres MP, Jones AM. Tyrosine phosphorylation switching of a G protein substrate. The Journal of Biological Chemistry. PMID 29382719 DOI: 10.1074/jbc.RA117.000163  0.52
2016 Kirkpatrick CL, Broberg CA, McCool EN, Lee WJ, Chao A, McConnell EW, Pritchard D, Hebert M, Fleeman R, Adams J, Jamil A, Madera L, Strömstedt AA, Goransson U, Liu Y, ... ... Hicks LM, et al. The 'PepSAVI-MS' pipeline for natural product bioactive peptide discovery. Analytical Chemistry. PMID 27991763 DOI: 10.1021/acs.analchem.6b03625  0.52
2016 Werth EG, McConnell EW, Gilbert TS, Couso Lianez I, Perez CA, Manley CK, Graves LM, Umen JG, Hicks LM. Probing the global kinome and phosphoproteome in Chlamydomonas reinhardtii via sequential enrichment and quantitative proteomics. The Plant Journal : For Cell and Molecular Biology. PMID 27671103 DOI: 10.1111/tpj.13384  0.52
2016 de A Soares E, Werth EG, Madroñero LJ, Ventura JA, Rodrigues SP, Hicks LM, Fernandes PM. Label-free quantitative proteomic analysis of pre-flowering PMeV-infected Carica papaya L. Journal of Proteomics. PMID 27343761 DOI: 10.1016/j.jprot.2016.06.025  0.52
2016 Huang H, Alvarez S, Bindbeutel R, Shen Z, Naldrett MJ, Evans BS, Briggs SP, Hicks LM, Kay SA, Nusinow DA. Identification of Evening Complex Associated Proteins in Arabidopsis by Affinity Purification and Mass Spectrometry. Molecular & Cellular Proteomics : McP. 15: 201-17. PMID 26545401 DOI: 10.1074/mcp.M115.054064  0.96
2015 Gargouri M, Park JJ, Holguin FO, Kim MJ, Wang H, Deshpande RR, Shachar-Hill Y, Hicks LM, Gang DR. Identification of regulatory network hubs that control lipid metabolism in Chlamydomonas reinhardtii. Journal of Experimental Botany. 66: 4551-66. PMID 26022256 DOI: 10.1093/jxb/erv217  0.96
2015 Alvarez S, Roy Choudhury S, Sivagnanam K, Hicks LM, Pandey S. Quantitative Proteomics Analysis of Camelina sativa Seeds Overexpressing the AGG3 Gene to Identify the Proteomic Basis of Increased Yield and Stress Tolerance. Journal of Proteome Research. 14: 2606-16. PMID 25944359 DOI: 10.1021/acs.jproteome.5b00150  0.96
2015 Slade WO, Werth EG, McConnell EW, Alvarez S, Hicks LM. Quantifying reversible oxidation of protein thiols in photosynthetic organisms. Journal of the American Society For Mass Spectrometry. 26: 631-40. PMID 25698223 DOI: 10.1007/s13361-014-1073-y  0.96
2015 Park JJ, Wang H, Gargouri M, Deshpande RR, Skepper JN, Holguin FO, Juergens MT, Shachar-Hill Y, Hicks LM, Gang DR. The response of Chlamydomonas reinhardtii to nitrogen deprivation: a systems biology analysis. The Plant Journal : For Cell and Molecular Biology. 81: 611-24. PMID 25515814 DOI: 10.1111/tpj.12747  0.96
2015 Juergens MT, Deshpande RR, Lucker BF, Park JJ, Wang H, Gargouri M, Holguin FO, Disbrow B, Schaub T, Skepper JN, Kramer DM, Gang DR, Hicks LM, Shachar-Hill Y. The regulation of photosynthetic structure and function during nitrogen deprivation in Chlamydomonas reinhardtii. Plant Physiology. 167: 558-73. PMID 25489023 DOI: 10.1104/pp.114.250530  0.96
2015 Rodrigues SP, Alvarez S, Werth EG, Slade WO, Gau B, Cahoon EB, Hicks LM. Multiplexing strategy for simultaneous detection of redox-, phospho- and total proteome-understanding TOR regulating pathways in Chlamydomonas reinhardtii Analytical Methods. 7: 7336-7344. DOI: 10.1039/c5ay00521c  0.96
2015 Jaiswal DK, Werth EG, McConnell EW, Hicks LM, Jones AM. Time-dependent, glucose-regulated Arabidopsis Regulator of G-protein Signaling 1 network Current Plant Biology. DOI: 10.1016/j.cpb.2015.11.002  0.96
2014 Wang H, Gau B, Slade WO, Juergens M, Li P, Hicks LM. The global phosphoproteome of Chlamydomonas reinhardtii reveals complex organellar phosphorylation in the flagella and thylakoid membrane. Molecular & Cellular Proteomics : McP. 13: 2337-53. PMID 24917610 DOI: 10.1074/mcp.M114.038281  0.96
2014 Slade WO, Werth EG, Chao A, Hicks LM. Phosphoproteomics in photosynthetic organisms. Electrophoresis. 35: 3441-51. PMID 24825726 DOI: 10.1002/elps.201400154  0.96
2013 Deng X, Weerapana E, Ulanovskaya O, Sun F, Liang H, Ji Q, Ye Y, Fu Y, Zhou L, Li J, Zhang H, Wang C, Alvarez S, Hicks LM, Lan L, et al. Proteome-wide quantification and characterization of oxidation-sensitive cysteines in pathogenic bacteria. Cell Host & Microbe. 13: 358-70. PMID 23498960 DOI: 10.1016/j.chom.2013.02.004  0.96
2013 Alvarez S, Roy Choudhury S, Hicks LM, Pandey S. Quantitative proteomics-based analysis supports a significant role of GTG proteins in regulation of ABA response in Arabidopsis roots. Journal of Proteome Research. 12: 1487-501. PMID 23336595 DOI: 10.1021/pr301159u  0.96
2012 Zhang M, Ravilious GE, Hicks LM, Jez JM, McCulla RD. Redox switching of adenosine-5'-phosphosulfate kinase with photoactivatable atomic oxygen precursors. Journal of the American Chemical Society. 134: 16979-82. PMID 23025382 DOI: 10.1021/ja3078522  0.96
2012 Sun F, Ding Y, Ji Q, Liang Z, Deng X, Wong CC, Yi C, Zhang L, Xie S, Alvarez S, Hicks LM, Luo C, Jiang H, Lan L, He C. Protein cysteine phosphorylation of SarA/MgrA family transcriptional regulators mediates bacterial virulence and antibiotic resistance. Proceedings of the National Academy of Sciences of the United States of America. 109: 15461-6. PMID 22927394 DOI: 10.1073/pnas.1205952109  0.96
2012 Sun F, Liang H, Kong X, Xie S, Cho H, Deng X, Ji Q, Zhang H, Alvarez S, Hicks LM, Bae T, Luo C, Jiang H, He C. Quorum-sensing agr mediates bacterial oxidation response via an intramolecular disulfide redox switch in the response regulator AgrA. Proceedings of the National Academy of Sciences of the United States of America. 109: 9095-100. PMID 22586129 DOI: 10.1073/pnas.1200603109  0.96
2012 Galant A, Koester RP, Ainsworth EA, Hicks LM, Jez JM. From climate change to molecular response: redox proteomics of ozone-induced responses in soybean. The New Phytologist. 194: 220-9. PMID 22272738 DOI: 10.1111/j.1469-8137.2011.04037.x  0.96
2012 Wang H, Alvarez S, Hicks LM. Comprehensive comparison of iTRAQ and label-free LC-based quantitative proteomics approaches using two Chlamydomonas reinhardtii strains of interest for biofuels engineering. Journal of Proteome Research. 11: 487-501. PMID 22059437 DOI: 10.1021/pr2008225  0.96
2012 Wang H, Wang S, Lu Y, Alvarez S, Hicks LM, Ge X, Xia Y. Proteomic analysis of early-responsive redox-sensitive proteins in Arabidopsis. Journal of Proteome Research. 11: 412-24. PMID 22050424 DOI: 10.1021/pr200918f  0.96
2011 Chen H, Zhang B, Hicks LM, Xiong L. A nucleotide metabolite controls stress-responsive gene expression and plant development. Plos One. 6: e26661. PMID 22028934 DOI: 10.1371/journal.pone.0026661  0.96
2011 Alvarez S, Hicks LM, Pandey S. ABA-dependent and -independent G-protein signaling in Arabidopsis roots revealed through an iTRAQ proteomics approach. Journal of Proteome Research. 10: 3107-22. PMID 21545083 DOI: 10.1021/pr2001786  0.96
2011 Zhang Y, Zhang B, Yan D, Dong W, Yang W, Li Q, Zeng L, Wang J, Wang L, Hicks LM, He Z. Two Arabidopsis cytochrome P450 monooxygenases, CYP714A1 and CYP714A2, function redundantly in plant development through gibberellin deactivation. The Plant Journal : For Cell and Molecular Biology. 67: 342-53. PMID 21457373 DOI: 10.1111/j.1365-313X.2011.04596.x  0.96
2011 Zhang B, Watts KM, Hodge D, Kemp LM, Hunstad DA, Hicks LM, Odom AR. A second target of the antimalarial and antibacterial agent fosmidomycin revealed by cellular metabolic profiling. Biochemistry. 50: 3570-7. PMID 21438569 DOI: 10.1021/bi200113y  0.96
2011 Alvarez S, Galant A, Jez JM, Hicks LM. Redox-regulatory mechanisms induced by oxidative stress in Brassica juncea roots monitored by 2-DE proteomics. Proteomics. 11: 1346-50. PMID 21365751 DOI: 10.1002/pmic.201000450  0.96
2011 Song CX, Szulwach KE, Fu Y, Dai Q, Yi C, Li X, Li Y, Chen CH, Zhang W, Jian X, Wang J, Zhang L, Looney TJ, Zhang B, Godley LA, ... Hicks LM, et al. Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine. Nature Biotechnology. 29: 68-72. PMID 21151123 DOI: 10.1038/nbt.1732  0.96
2010 Chen Q, Westfall CS, Hicks LM, Wang S, Jez JM. Kinetic basis for the conjugation of auxin by a GH3 family indole-acetic acid-amido synthetase. The Journal of Biological Chemistry. 285: 29780-6. PMID 20639576 DOI: 10.1074/jbc.M110.146431  0.96
2010 Zhang B, Tolstikov V, Turnbull C, Hicks LM, Fiehn O. Divergent metabolome and proteome suggest functional independence of dual phloem transport systems in cucurbits. Proceedings of the National Academy of Sciences of the United States of America. 107: 13532-7. PMID 20566864 DOI: 10.1073/pnas.0910558107  0.96
2010 Marsh E, Alvarez S, Hicks LM, Barbazuk WB, Qiu W, Kovacs L, Schachtman D. Changes in protein abundance during powdery mildew infection of leaf tissues of Cabernet Sauvignon grapevine (Vitis vinifera L.). Proteomics. 10: 2057-64. PMID 20232356 DOI: 10.1002/pmic.200900712  0.96
2010 Ning J, Li X, Hicks LM, Xiong L. A Raf-like MAPKKK gene DSM1 mediates drought resistance through reactive oxygen species scavenging in rice. Plant Physiology. 152: 876-90. PMID 20007444 DOI: 10.1104/pp.109.149856  0.96
2010 Wu B, Zhang B, Feng X, Rubens JR, Huang R, Hicks LM, Pakrasi HB, Tang YJ. Alternative isoleucine synthesis pathway in cyanobacterial species. Microbiology (Reading, England). 156: 596-602. PMID 19875435 DOI: 10.1099/mic.0.031799-0  0.96
2009 Feng X, Mouttaki H, Lin L, Huang R, Wu B, Hemme CL, He Z, Zhang B, Hicks LM, Xu J, Zhou J, Tang YJ. Characterization of the central metabolic pathways in Thermoanaerobacter sp. strain X514 via isotopomer-assisted metabolite analysis. Applied and Environmental Microbiology. 75: 5001-8. PMID 19525270 DOI: 10.1128/AEM.00715-09  0.96
2009 Chen Q, Zhang B, Hicks LM, Wang S, Jez JM. A liquid chromatography-tandem mass spectrometry-based assay for indole-3-acetic acid-amido synthetase. Analytical Biochemistry. 390: 149-54. PMID 19393612 DOI: 10.1016/j.ab.2009.04.027  0.96
2009 Alvarez S, Berla BM, Sheffield J, Cahoon RE, Jez JM, Hicks LM. Comprehensive analysis of the Brassica juncea root proteome in response to cadmium exposure by complementary proteomic approaches. Proteomics. 9: 2419-31. PMID 19343712 DOI: 10.1002/pmic.200800478  0.96
2008 Chen H, Hu J, Chen PR, Lan L, Li Z, Hicks LM, Dinner AR, He C. The Pseudomonas aeruginosa multidrug efflux regulator MexR uses an oxidation-sensing mechanism. Proceedings of the National Academy of Sciences of the United States of America. 105: 13586-91. PMID 18757728 DOI: 10.1073/pnas.0803391105  0.96
2008 Schroeder AC, Kumaran S, Hicks LM, Cahoon RE, Halls C, Yu O, Jez JM. Contributions of conserved serine and tyrosine residues to catalysis, ligand binding, and cofactor processing in the active site of tyrosine ammonia lyase. Phytochemistry. 69: 1496-506. PMID 18346767 DOI: 10.1016/j.phytochem.2008.02.007  0.96
2008 Nagamune K, Hicks LM, Fux B, Brossier F, Chini EN, Sibley LD. Abscisic acid controls calcium-dependent egress and development in Toxoplasma gondii. Nature. 451: 207-10. PMID 18185591 DOI: 10.1038/nature06478  0.96
2007 Jez JM, Schachtman DP, Berg RH, Taylor CG, Chen S, Hicks LM, Jaworski JG, Smith TJ, Nielsen E, Pikaard CS. Developing a new interdisciplinary lab course for undergraduate and graduate students: Plant cells and proteins. Biochemistry and Molecular Biology Education : a Bimonthly Publication of the International Union of Biochemistry and Molecular Biology. 35: 410-5. PMID 21591136 DOI: 10.1002/bmb.99  0.96
2007 Earley KW, Shook MS, Brower-Toland B, Hicks L, Pikaard CS. In vitro specificities of Arabidopsis co-activator histone acetyltransferases: Implications for histone hyperacetylation in gene activation Plant Journal. 52: 615-626. PMID 17877703 DOI: 10.1111/j.1365-313X.2007.03264.x  0.96
2007 Hicks LM, Cahoon RE, Bonner ER, Rivard RS, Sheffield J, Jez JM. Thiol-based regulation of redox-active glutamate-cysteine ligase from Arabidopsis thaliana. The Plant Cell. 19: 2653-61. PMID 17766407 DOI: 10.1105/tpc.107.052597  0.96
2007 Brendza KM, Haakenson W, Cahoon RE, Hicks LM, Palavalli LH, Chiapelli BJ, McLaird M, McCarter JP, Williams DJ, Hresko MC, Jez JM. Phosphoethanolamine N-methyltransferase (PMT-1) catalyses the first reaction of a new pathway for phosphocholine biosynthesis in Caenorhabditis elegans. The Biochemical Journal. 404: 439-48. PMID 17313371 DOI: 10.1042/BJ20061815  0.96
2006 Hicks LM, Moffitt MC, Beer LL, Moore BS, Kelleher NL. Structural characterization of in vitro and in vivo intermediates on the loading module of microcystin synthetase. Acs Chemical Biology. 1: 93-102. PMID 17163649 DOI: 10.1021/cb500007v  0.96
2006 Hicks LM, Balibar CJ, Walsh CT, Kelleher NL, Hillson NJ. Probing intra- versus interchain kinetic preferences of L-Thr acylation on dimeric VibF with mass spectrometry. Biophysical Journal. 91: 2609-19. PMID 16815901 DOI: 10.1529/biophysj.106.084848  0.96
2006 Palavalli LH, Brendza KM, Haakenson W, Cahoon RE, McLaird M, Hicks LM, McCarter JP, Williams DJ, Hresko MC, Jez JM. Defining the role of phosphomethylethanolamine N-methyltransferase from Caenorhabditis elegans in phosphocholine biosynthesis by biochemical and kinetic analysis. Biochemistry. 45: 6056-65. PMID 16681378 DOI: 10.1021/bi060199d  0.96
2006 Hicks LM, Mazur MT, Miller LM, Dorrestein PC, Schnarr NA, Khosla C, Kelleher NL. Investigating nonribosomal peptide and polyketide biosynthesis by direct detection of intermediates on >70 kDa polypeptides by using Fourier-transform mass spectrometry. Chembiochem : a European Journal of Chemical Biology. 7: 904-7. PMID 16642537 DOI: 10.1002/cbic.200500416  0.96
2006 Zhang Z, An X, Yang K, Perlstein DL, Hicks L, Kelleher N, Stubbe J, Huang M. Nuclear localization of the Saccharomyces cerevisiae ribonucleotide reductase small subunit requires a karyopherin and a WD40 repeat protein. Proceedings of the National Academy of Sciences of the United States of America. 103: 1422-7. PMID 16432237 DOI: 10.1073/pnas.0510516103  0.96
2005 Kelleher NL, Hicks LM. Contemporary mass spectrometry for the direct detection of enzyme intermediates. Current Opinion in Chemical Biology. 9: 424-30. PMID 16129650 DOI: 10.1016/j.cbpa.2005.08.018  0.96
2004 Hicks LM, O'Connor SE, Mazur MT, Walsh CT, Kelleher NL. Mass spectrometric interrogation of thioester-bound intermediates in the initial stages of epothilone biosynthesis. Chemistry & Biology. 11: 327-35. PMID 15123262 DOI: 10.1016/j.chembiol.2004.02.021  0.96
2003 Hicks L, Weinreb P, Konz D, Marahiel MA, Walsh CT, Kelleher NL. Fourier-transform mass spectrometry for detection of thioester-bound intermediates in unfractionated proteolytic mixtures of 80 and 191 kDa portions of Bacitracin A synthetase Analytica Chimica Acta. 496: 217-224. DOI: 10.1016/S0003-2670(03)01001-8  0.96
2002 Mazur MT, Miller LM, McLoughlin SM, Luo L, Hicks LM, Wang J, Walsh CT, Kelleher NL. Online capillary LC-FTMS for the analysis of covalent enzyme intermediates of polyketide and nonribosomal peptide synthetases Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 357-358.  0.96
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