James Dennis - Publications

Molecular Genetics University of Toronto, Samuel Lunenfeld Research Institute 

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Ryczko MC, Pawling J, Chen R, Abdel Rahman AM, Yau K, Copeland JK, Zhang C, Surendra A, Guttman DS, Figeys D, Dennis JW. Metabolic Reprogramming by Hexosamine Biosynthetic and Golgi N-Glycan Branching Pathways. Scientific Reports. 6: 23043. PMID 26972830 DOI: 10.1038/Srep23043  0.4
2015 Dennis JW. Many Light Touches Convey the Message. Trends in Biochemical Sciences. 40: 673-86. PMID 26439532 DOI: 10.1016/j.tibs.2015.08.010  0.4
2015 Nabi IR, Shankar J, Dennis JW. The galectin lattice at a glance. Journal of Cell Science. PMID 26092931 DOI: 10.1242/jcs.151159  0.4
2015 Abdel Rahman AM, Ryczko M, Nakano M, Pawling J, Rodrigues T, Johswich A, Taniguchi N, Dennis JW. Golgi N-glycan branching N-acetylglucosaminyltransferases I, V and VI promote nutrient uptake and metabolism. Glycobiology. 25: 225-40. PMID 25395405 DOI: 10.1093/glycob/cwu105  0.4
2014 Abdel Rahman AM, Pawling J, Ryczko M, Caudy AA, Dennis JW. Targeted metabolomics in cultured cells and tissues by mass spectrometry: method development and validation. Analytica Chimica Acta. 845: 53-61. PMID 25201272 DOI: 10.1016/j.aca.2014.06.012  0.4
2014 Johswich A, Longuet C, Pawling J, Abdel Rahman A, Ryczko M, Drucker DJ, Dennis JW. N-glycan remodeling on glucagon receptor is an effector of nutrient sensing by the hexosamine biosynthesis pathway. The Journal of Biological Chemistry. 289: 15927-41. PMID 24742675 DOI: 10.1074/jbc.M114.563734  0.4
2014 Williams R, Ma X, Schott RK, Mohammad N, Ho CY, Li CF, Chang BS, Demetriou M, Dennis JW. Encoding asymmetry of the N-glycosylation motif facilitates glycoprotein evolution. Plos One. 9: e86088. PMID 24475074 DOI: 10.1371/journal.pone.0086088  0.4
2014 Soliman MA, Abdel Rahman AM, Lamming DW, Birsoy K, Pawling J, Frigolet ME, Lu H, Fantus IG, Pasculescu A, Zheng Y, Sabatini DM, Dennis JW, Pawson T. A correction to the research article titled: "The adaptor protein p66Shc inhibits mTOR-dependent anabolic metabolism" (Science Signaling (2014)) Science Signaling. 7. DOI: 10.1126/scisignal.7315er2  0.4
2012 Beheshti Zavareh R, Sukhai MA, Hurren R, Gronda M, Wang X, Simpson CD, Maclean N, Zih F, Ketela T, Swallow CJ, Moffat J, Rose DR, Schachter H, Schimmer AD, Dennis JW. Suppression of cancer progression by MGAT1 shRNA knockdown. Plos One. 7: e43721. PMID 22957033 DOI: 10.1371/Journal.Pone.0043721  0.4
2012 Boscher C, Zheng YZ, Lakshminarayan R, Johannes L, Dennis JW, Foster LJ, Nabi IR. Galectin-3 protein regulates mobility of N-cadherin and GM1 ganglioside at cell-cell junctions of mammary carcinoma cells. The Journal of Biological Chemistry. 287: 32940-52. PMID 22846995 DOI: 10.1074/jbc.M112.353334  0.4
2010 Wellen KE, Lu C, Mancuso A, Lemons JM, Ryczko M, Dennis JW, Rabinowitz JD, Coller HA, Thompson CB. The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism. Genes & Development. 24: 2784-99. PMID 21106670 DOI: 10.1101/Gad.1985910  0.4
2010 Shi Y, Tomic J, Wen F, Shaha S, Bahlo A, Harrison R, Dennis JW, Williams R, Gross BJ, Walker S, Zuccolo J, Deans JP, Hart GW, Spaner DE. Aberrant O-GlcNAcylation characterizes chronic lymphocytic leukemia. Leukemia. 24: 1588-98. PMID 20668475 DOI: 10.1038/Leu.2010.152  0.4
2010 Rosario CO, Ko MA, Haffani YZ, Gladdy RA, Paderova J, Pollett A, Squire JA, Dennis JW, Swallow CJ. Plk4 is required for cytokinesis and maintenance of chromosomal stability. Proceedings of the National Academy of Sciences of the United States of America. 107: 6888-93. PMID 20348415 DOI: 10.1073/Pnas.0910941107  0.4
2008 Lau KS, Dennis JW. N-Glycans in cancer progression. Glycobiology. 18: 750-60. PMID 18701722 DOI: 10.1093/glycob/cwn071  0.4
2008 Beheshti Zavareh R, Lau KS, Hurren R, Datti A, Ashline DJ, Gronda M, Cheung P, Simpson CD, Liu W, Wasylishen AR, Boutros PC, Shi H, Vengopal A, Jurisica I, Penn LZ, ... ... Dennis JW, et al. Inhibition of the sodium/potassium ATPase impairs N-glycan expression and function. Cancer Research. 68: 6688-97. PMID 18701493 DOI: 10.1158/0008-5472.Can-07-6833  0.4
2008 Lau KS, Khan S, Dennis JW. Genome-scale identification of UDP-GlcNAc-dependent pathways. Proteomics. 8: 3294-302. PMID 18646010 DOI: 10.1002/pmic.200800208  0.4
2008 Xu GW, Mawji IA, Macrae CJ, Koch CA, Datti A, Wrana JL, Dennis JW, Schimmer AD. A high-content chemical screen identifies ellipticine as a modulator of p53 nuclear localization. Apoptosis : An International Journal On Programmed Cell Death. 13: 413-22. PMID 18181020 DOI: 10.1007/s10495-007-0175-4  0.4
2008 Soleimani L, Roder JC, Dennis JW, Lipina T. Beta N-acetylglucosaminyltransferase V (Mgat5) deficiency reduces the depression-like phenotype in mice. Genes, Brain, and Behavior. 7: 334-43. PMID 17883406 DOI: 10.1111/J.1601-183X.2007.00358.X  0.4
2008 Jarjanazi H, Savas S, Pabalan N, Dennis JW, Ozcelik H. Biological implications of SNPs in signal peptide domains of human proteins. Proteins. 70: 394-403. PMID 17680692 DOI: 10.1002/Prot.21548  0.4
2007 Mendelsohn R, Cheung P, Berger L, Partridge E, Lau K, Datti A, Pawling J, Dennis JW. Complex N-glycan and metabolic control in tumor cells. Cancer Research. 67: 9771-80. PMID 17942907 DOI: 10.1158/0008-5472.CAN-06-4580  0.4
2007 Grigorian A, Lee SU, Tian W, Chen IJ, Gao G, Mendelsohn R, Dennis JW, Demetriou M. Control of T Cell-mediated autoimmunity by metabolite flux to N-glycan biosynthesis. The Journal of Biological Chemistry. 282: 20027-35. PMID 17488719 DOI: 10.1074/jbc.M701890200  0.4
2007 Lau KS, Partridge EA, Grigorian A, Silvescu CI, Reinhold VN, Demetriou M, Dennis JW. Complex N-glycan number and degree of branching cooperate to regulate cell proliferation and differentiation. Cell. 129: 123-34. PMID 17418791 DOI: 10.1016/J.Cell.2007.01.049  0.4
2007 Cheung P, Dennis JW. Mgat5 and Pten interact to regulate cell growth and polarity. Glycobiology. 17: 767-73. PMID 17400585 DOI: 10.1093/glycob/cwm037  0.4
2005 Ko MA, Rosario CO, Hudson JW, Kulkarni S, Pollett A, Dennis JW, Swallow CJ. Plk4 haploinsufficiency causes mitotic infidelity and carcinogenesis. Nature Genetics. 37: 883-8. PMID 16025114 DOI: 10.1038/ng1605  0.4
2005 Jia Z, Barbier L, Stuart H, Amraei M, Pelech S, Dennis JW, Metalnikov P, O'Donnell P, Nabi IR. Tumor cell pseudopodial protrusions. Localized signaling domains coordinating cytoskeleton remodeling, cell adhesion, glycolysis, RNA translocation, and protein translation. The Journal of Biological Chemistry. 280: 30564-73. PMID 15985431 DOI: 10.1074/jbc.M501754200  0.4
2005 Swallow CJ, Ko MA, Siddiqui NU, Hudson JW, Dennis JW. Sak/Plk4 and mitotic fidelity. Oncogene. 24: 306-12. PMID 15640847 DOI: 10.1038/sj.onc.1208275  0.4
2004 Swallow CJ, Partridge EA, Macmillan JC, Tajirian T, DiGuglielmo GM, Hay K, Szweras M, Jahnen-Dechent W, Wrana JL, Redston M, Gallinger S, Dennis JW. alpha2HS-glycoprotein, an antagonist of transforming growth factor beta in vivo, inhibits intestinal tumor progression. Cancer Research. 64: 6402-9. PMID 15374947 DOI: 10.1158/0008-5472.Can-04-1117  0.4
2002 Leung GC, Hudson JW, Kozarova A, Davidson A, Dennis JW, Sicheri F. The Sak polo-box comprises a structural domain sufficient for mitotic subcellular localization Nature Structural Biology. 9: 719-724. PMID 12352953 DOI: 10.1038/Nsb848  0.4
2002 Warren CE, Krizus A, Roy PJ, Culotti JG, Dennis JW. The Caenorhabditis elegans gene, gly-2, can rescue the N-acetylglucosaminyltransferase V mutation of Lec4 cells. The Journal of Biological Chemistry. 277: 22829-38. PMID 11937505 DOI: 10.1074/jbc.M201390200  0.4
2002 Szweras M, Liu D, Partridge EA, Pawling J, Sukhu B, Clokie C, Jahnen-Dechent W, Tenenbaum HC, Swallow CJ, Grynpas MD, Dennis JW. alpha 2-HS glycoprotein/fetuin, a transforming growth factor-beta/bone morphogenetic protein antagonist, regulates postnatal bone growth and remodeling. The Journal of Biological Chemistry. 277: 19991-7. PMID 11901155 DOI: 10.1074/Jbc.M112234200  0.4
2001 Dennis JW, Warren CE, Granovsky M, Demetriou M. Genetic defects in N-glycosylation and cellular diversity in mammals Current Opinion in Structural Biology. 11: 601-607. PMID 11785762 DOI: 10.1016/S0959-440X(00)00254-2  0.4
2001 Warren CE, Krizus A, Dennis JW. Complementary expression patterns of six nonessential Caenorhabditis elegans core 2/I N-acetylglucosaminyltransferase homologues Glycobiology. 11: 979-988. PMID 11744632 DOI: 10.1093/glycob/11.11.979  0.4
2001 Macmillan JC, Hudson JW, Bull S, Dennis JW, Swallow CJ. Comparative expression of the mitotic regulators SAK and PLK in colorectal cancer. Annals of Surgical Oncology. 8: 729-40. PMID 11597015 DOI: 10.1007/S10434-001-0729-6  0.4
2001 Hudson JW, Kozarova A, Cheung P, Macmillan JC, Swallow CJ, Cross JC, Dennis JW. Late mitotic failure in mice lacking Sak, a polo-like kinase Current Biology. 11: 441-446. PMID 11301255 DOI: 10.1016/S0960-9822(01)00117-8  0.4
2000 Hudson JW, Chen L, Fode C, Binkert C, Dennis JW. Sak kinase gene structure and transcriptional regulation. Gene. 241: 65-73. PMID 10607900 DOI: 10.1016/S0378-1119(99)00467-9  0.4
1999 Koya D, Dennis JW, Warren CE, Takahara N, Schoen FJ, Nishio Y, Nakajima T, Lipes MA, King GL. Overexpression of core 2 N-acetylglycosaminyltransferase enhances cytokine actions and induces hypertrophic myocardium in transgenic mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 13: 2329-37. PMID 10593880 DOI: 10.1096/fasebj.13.15.2329  0.4
1999 Dennis JW, Granovsky M, Warren CE. Glycoprotein glycosylation and cancer progression Biochimica Et Biophysica Acta - General Subjects. 1473: 21-34. PMID 10580127 DOI: 10.1016/S0304-4165(99)00167-1  0.4
1999 Dennis JW, Granovsky M, Warren CE. Protein glycosylation in development and disease Bioessays. 21: 412-421. PMID 10376012 DOI: 10.1002/(SICI)1521-1878(199905)21:5<412::AID-BIES8>3.0.CO;2-5  0.4
1997 Barran P, Fellinger W, Warren CE, Dennis JW, Ziltener HJ. Modification of CD43 and other lymphocyte O-glycoproteins by core 2 n-acetylglucosaminyltransferase Glycobiology. 7: 129-136. PMID 9061371 DOI: 10.1093/glycob/7.1.129  0.4
1995 Granovsky M, Fode C, Warren CE, Campbell RM, Marth JD, Pierce M, Fregien N, Dennis JW. GlcNAc-transferase V and core 2 GlcNAc-transferase expression in the developing mouse embryo Glycobiology. 5: 797-806. PMID 8720078 DOI: 10.1093/glycob/5.8.797  0.4
1995 Campbell RM, Metzler M, Granovsky M, Dennis JW, Marth JD. Complex asparagine-linked oligosaccharides in Mgat1-null embryos Glycobiology. 5: 535-543. PMID 8563140 DOI: 10.1093/glycob/5.5.535  0.4
1995 Nishio Y, Warren CE, Buczek-Thomas JA, Rulfs J, Koya D, Aiello LP, Feener EP, Miller TB, Dennis JW, King GL. Identification and characterization of a gene regulating enzymatic glycosylation which is induced by diabetes and hyperglycemia specifically in rat cardiac tissue Journal of Clinical Investigation. 96: 1759-1767. PMID 7560067 DOI: 10.1172/JCI118221  0.4
1993 Cummings L, Warren CE, Granovsky M, Dennis JW. Antisense and sense cDNA expression cloning using autonomously replicating vectors and toxic lectin selection Biochemical and Biophysical Research Communications. 195: 814-822. PMID 8373417 DOI: 10.1006/bbrc.1993.2118  0.4
1991 Shaw L, Yousefi S, Dennis JW, Schauer R. CMP-N-acetylneuraminic acid hydroxylase activity determines the wheat germ agglutinin-binding phenotype in two mutants of the lymphoma cell line MDAY-D2 Glycoconjugate Journal. 8: 434-441. PMID 1841685 DOI: 10.1007/BF00731295  0.4
1989 Greer WL, Higgins E, Sutherland DR, Novogrodsky A, Brockhausen I, Peacocke M, Rubin LA, Baker M, Dennis JW, Siminovitch KA. Altered expression of leucocyte sialoglycoprotein in Wiskott-Aldrich syndrome is associated with a specific defect in O-glycosylation. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 67: 503-9. PMID 2803729 DOI: 10.1139/o89-081  0.4
1987 Kiyohara T, Dennis JW, Roder JC. Double restriction in NK cell recognition is linked to transmethylation and can be triggered by asparagine-linked oligosaccharides on tumor cells. Cellular Immunology. 106: 223-33. PMID 3568148 DOI: 10.1016/0008-8749(87)90166-3  0.4
1986 Dennis JW, Laferté S, Fukuda M, Dell A, Carver JP. Asn-linked oligosaccharides in lectin-resistant tumor-cell mutants with varying metastatic potential European Journal of Biochemistry. 161: 359-373. PMID 3780748 DOI: 10.1111/J.1432-1033.1986.Tb10455.X  0.4
1984 Dennis JW, Carver JP, Schachter H. Asparagine-linked oligosaccharides in murine tumor cells: comparison of a WGA-resistant (WGAr) nonmetastatic mutant and a related WGA-sensitive (WGAs) metastatic line. The Journal of Cell Biology. 99: 1034-44. PMID 6547960 DOI: 10.1083/Jcb.99.3.1034  0.4
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