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Steve A. Soper - Publications

Affiliations: 
Biomedical Engineering University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Development of Micro- and Nanofabricated Tools for Biological Discovery and Medical Diagnostics
Website:
http://www.chem.unc.edu/people/faculty/soper/index.html

241 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Weerakoon-Ratnayake KM, Uba FI, Oliver-Calixte NJ, Soper SA. Electrophoretic Separation of Single Particles Using Nanoscale Thermoplastic Columns. Analytical Chemistry. PMID 26963496 DOI: 10.1021/acs.analchem.5b04065  1
2016 O'Neil CE, Jackson JM, Shim SH, Soper SA. Interrogating Surface Functional Group Heterogeneity of Activated Thermoplastics Using Super-Resolution Fluorescence Microscopy. Analytical Chemistry. PMID 26927303 DOI: 10.1021/acs.analchem.5b04472  1
2015 Jackson JM, Taylor JB, Witek MA, Hunsucker SA, Waugh JP, Fedoriw Y, Shea TC, Soper SA, Armistead PM. Microfluidics for the detection of minimal residual disease in acute myeloid leukemia patients using circulating leukemic cells selected from blood. The Analyst. PMID 26523411 DOI: 10.1039/c5an01836f  1
2015 Xia K, Novak BR, Weerakoon-Ratnayake KM, Soper SA, Nikitopoulos DE, Moldovan D. Electrophoretic Transport of Single DNA Nucleotides through Nanoslits: A Molecular Dynamics Simulation Study. The Journal of Physical Chemistry. B. 119: 11443-58. PMID 26237155 DOI: 10.1021/acs.jpcb.5b02798  1
2015 Pullagurla SR, Baird AE, Adamski MG, Soper SA. Current and future bioanalytical approaches for stroke assessment. Bioanalysis. 7: 1017-35. PMID 25966012 DOI: 10.4155/bio.15.40  1
2015 Baird AE, Soper SA, Pullagurla SR, Adamski MG. Recent and near-future advances in nucleic acid-based diagnosis of stroke. Expert Review of Molecular Diagnostics. 15: 665-79. PMID 25837776 DOI: 10.1586/14737159.2015.1024660  1
2015 Nair SV, Witek MA, Jackson JM, Lindell MA, Hunsucker SA, Sapp T, Perry CE, Hupert ML, Bae-Jump V, Gehrig PA, Wysham WZ, Armistead PM, Voorhees P, Soper SA. Enzymatic cleavage of uracil-containing single-stranded DNA linkers for the efficient release of affinity-selected circulating tumor cells. Chemical Communications (Cambridge, England). 51: 3266-9. PMID 25616078 DOI: 10.1039/c4cc09765c  1
2015 Uba FI, Hu B, Weerakoon-Ratnayake K, Oliver-Calixte N, Soper SA. High process yield rates of thermoplastic nanofluidic devices using a hybrid thermal assembly technique. Lab On a Chip. 15: 1038-49. PMID 25511610 DOI: 10.1039/c4lc01254b  1
2014 Hupert ML, Jackson JM, Wang H, Witek MA, Kamande J, Milowsky MI, Whang YE, Soper SA. Arrays of High-Aspect Ratio Microchannels for High-Throughput Isolation of Circulating Tumor Cells (CTCs). Microsystem Technologies : Sensors, Actuators, Systems Integration. 20: 1815-1825. PMID 25349469 DOI: 10.1007/s00542-013-1941-6  1
2014 Adamski MG, Li Y, Wagner E, Yu H, Seales-Bailey C, Soper SA, Murphy M, Baird AE. Expression profile based gene clusters for ischemic stroke detection. Genomics. 104: 163-9. PMID 25135788 DOI: 10.1016/j.ygeno.2014.08.004  1
2014 Adamski MG, Li Y, Wagner E, Yu H, Seales-Bailey C, Durkin H, Hao Q, Soper SA, Murphy M, Baird AE. Pre-existing hypertension dominates γδT cell reduction in human ischemic stroke. Plos One. 9: e97755. PMID 24840735 DOI: 10.1371/journal.pone.0097755  1
2014 Pullagurla SR, Witek MA, Jackson JM, Lindell MA, Hupert ML, Nesterova IV, Baird AE, Soper SA. Parallel affinity-based isolation of leukocyte subsets using microfluidics: application for stroke diagnosis. Analytical Chemistry. 86: 4058-65. PMID 24650222 DOI: 10.1021/ac5007766  1
2014 Oliver-Calixte NJ, Uba FI, Battle KN, Weerakoon-Ratnayake KM, Soper SA. Immobilization of lambda exonuclease onto polymer micropillar arrays for the solid-phase digestion of dsDNAs. Analytical Chemistry. 86: 4447-54. PMID 24628008 DOI: 10.1021/ac5002965  1
2014 Torphy RJ, Tignanelli CJ, Kamande JW, Moffitt RA, Herrera Loeza SG, Soper SA, Yeh JJ. Circulating tumor cells as a biomarker of response to treatment in patient-derived xenograft mouse models of pancreatic adenocarcinoma. Plos One. 9: e89474. PMID 24586805 DOI: 10.1371/journal.pone.0089474  1
2014 Battle KN, Uba FI, Soper SA. Microfluidics for the analysis of membrane proteins: how do we get there? Electrophoresis. 35: 2253-66. PMID 24585436 DOI: 10.1002/elps.201300625  1
2014 Battle KN, Jackson JM, Witek MA, Hupert ML, Hunsucker SA, Armistead PM, Soper SA. Solid-phase extraction and purification of membrane proteins using a UV-modified PMMA microfluidic bioaffinity μSPE device. The Analyst. 139: 1355-63. PMID 24487280 DOI: 10.1039/c3an02400h  1
2014 Jackson JM, Witek MA, Hupert ML, Brady C, Pullagurla S, Kamande J, Aufforth RD, Tignanelli CJ, Torphy RJ, Yeh JJ, Soper SA. UV activation of polymeric high aspect ratio microstructures: ramifications in antibody surface loading for circulating tumor cell selection. Lab On a Chip. 14: 106-17. PMID 23900277 DOI: 10.1039/c3lc50618e  1
2014 Jackson JM, Hupert ML, Soper SA. Discrete geometry optimization for reducing flow non-uniformity, asymmetry, and parasitic minor loss pressure drops in Z-type configurations of fuel cells Journal of Power Sources. 269: 274-283. DOI: 10.1016/j.jpowsour.2014.06.136  1
2014 Kim N, Murphy MC, Soper SA, Nikitopoulos DE. Liquid-liquid segmented flows in polycarbonate microchannels with cross-sectional expansions International Journal of Multiphase Flow. 58: 83-96. DOI: 10.1016/j.ijmultiphaseflow.2013.09.002  1
2014 Jackson JM, Nair SV, Witek MA, Hupert ML, Hunsucker SA, Fedoriw Y, Armistead PM, Soper SA. Microfluidic platform for detecting circulating leukemic cells: Analysis of minimum residual disease in acute myeloid leukemia as a case example 18th International Conference On Miniaturized Systems For Chemistry and Life Sciences, Microtas 2014. 929-931.  1
2014 O'Neil C, Uba F, Pullagurla S, Ratnayake K, Shim SH, Cho Y, Soper SA. Elucidating transport dynamics of single molecules in thermoplastic nanochanels 18th International Conference On Miniaturized Systems For Chemistry and Life Sciences, Microtas 2014. 1332-1334.  1
2014 Uba FI, Ratnayake KMW, Wu J, Cho YK, Shin HJ, Soper SA. Development of an integrated nanofluidic device for the detection of sequence variations in dsDNA 18th International Conference On Miniaturized Systems For Chemistry and Life Sciences, Microtas 2014. 2005-2007.  1
2014 Ha HY, Park YS, Park DK, Uba FI, Soper SA, Cho YK. Digital counting of bacteria by using a microfluidic chip with built-in electrodes 18th International Conference On Miniaturized Systems For Chemistry and Life Sciences, Microtas 2014. 1704-1706.  1
2014 Park DS, Young B, You BH, Singh V, Soper SA, Baird A, Murphy MC. Optical waveguide integrated with a coupling prism and microlenses 18th International Conference On Miniaturized Systems For Chemistry and Life Sciences, Microtas 2014. 2280-2282.  1
2014 Brown CR, Park T, Chen PC, You BH, Park DS, Soper SA, Murphy MC. An experimental validation of the pressure capacity of a modular gasketless microfludic interconnect 18th International Conference On Miniaturized Systems For Chemistry and Life Sciences, Microtas 2014. 1665-1667.  1
2013 Kamande JW, Hupert ML, Witek MA, Wang H, Torphy RJ, Dharmasiri U, Njoroge SK, Jackson JM, Aufforth RD, Snavely A, Yeh JJ, Soper SA. Modular microsystem for the isolation, enumeration, and phenotyping of circulating tumor cells in patients with pancreatic cancer. Analytical Chemistry. 85: 9092-100. PMID 23947293 DOI: 10.1021/ac401720k  1
2013 Rani SD, Park T, You BH, Soper SA, Murphy MC, Nikitopoulos DE. Modeling of misalignment effects in microfluidic interconnects for modular bio-analytical chip applications. Electrophoresis. 34: 2988-95. PMID 23893860 DOI: 10.1002/elps.201300110  1
2013 Peng Z, Young B, Baird AE, Soper SA. Single-pair fluorescence resonance energy transfer analysis of mRNA transcripts for highly sensitive gene expression profiling in near real time. Analytical Chemistry. 85: 7851-8. PMID 23869556 DOI: 10.1021/ac400729q  1
2013 Balamurugan S, Mayer KM, Lee S, Soper SA, Hafner JH, Spivak DA. Nanostructure shape effects on response of plasmonic aptamer sensors. Journal of Molecular Recognition : Jmr. 26: 402-7. PMID 23836467 DOI: 10.1002/jmr.2278  1
2013 Adamski MG, Li Y, Wagner E, Yu H, Seales-Bailey C, Soper SA, Murphy M, Baird AE. Next-generation qPCR for the high-throughput measurement of gene expression in multiple leukocyte subsets. Journal of Biomolecular Screening. 18: 1008-17. PMID 23690294 DOI: 10.1177/1087057113489882  1
2013 Zhang X, Xu S, Lee YI, Soper SA. LED-induced in-column molecular imprinting for solid phase extraction/capillary electrophoresis. The Analyst. 138: 2821-4. PMID 23571275 DOI: 10.1039/c3an00257h  1
2013 Rani SD, You BH, Soper SA, Murphy MC, Nikitopoulos DE. Influence of material transition and interfacial area changes on flow and concentration in electro-osmotic flows. Analytica Chimica Acta. 770: 103-10. PMID 23498692 DOI: 10.1016/j.aca.2013.01.047  1
2013 Novak BR, Moldovan D, Nikitopoulos DE, Soper SA. Distinguishing single DNA nucleotides based on their times of flight through nanoslits: a molecular dynamics simulation study. The Journal of Physical Chemistry. B. 117: 3271-9. PMID 23461845 DOI: 10.1021/jp309486c  1
2013 Chen YW, Wang H, Hupert M, Soper SA. Identification of methicillin-resistant Staphylococcus aureus using an integrated and modular microfluidic system. The Analyst. 138: 1075-83. PMID 23308354 DOI: 10.1039/c2an36430a  1
2013 Albrecht JC, Kotani A, Lin JS, Soper SA, Barron AE. Simultaneous detection of 19 K-ras mutations by free-solution conjugate electrophoresis of ligase detection reaction products on glass microchips. Electrophoresis. 34: 590-7. PMID 23192597 DOI: 10.1002/elps.201200462  1
2013 Kim H, Soper SA, Podlaha EJ. Pulse electrodeposition of multi-segmented super invar/au nanowires Ecs Transactions. 53: 9-14. DOI: 10.1149/05311.0009ecst  1
2013 Park DS, Lowrey BB, Brown CR, You BH, Singh V, Soper SA, Baird A, Murphy MC. Multiplex single molecule detection module for stroke diagnosis Asme International Mechanical Engineering Congress and Exposition, Proceedings (Imece). 10. DOI: 10.1115/IMECE2013-65524  1
2013 Wang S, Njoroge SK, Battle K, Soper SA, Feng J. Two-dimensional nitrosylated protein separation in poly (methyl methacrylate) microchips Ifmbe Proceedings. 39: 294-296. DOI: 10.1007/978-3-642-29305-4_79  1
2013 Hollins BC, Soper SA, Feng J. Microfluidic carbonylated protein capture Ifmbe Proceedings. 39: 270-273. DOI: 10.1007/978-3-642-29305-4_73  1
2012 Chen YW, Wang H, Hupert M, Witek M, Dharmasiri U, Pingle MR, Barany F, Soper SA. Modular microfluidic system fabricated in thermoplastics for the strain-specific detection of bacterial pathogens. Lab On a Chip. 12: 3348-55. PMID 22859220 DOI: 10.1039/c2lc40805h  1
2012 Wang S, Njoroge SK, Battle K, Zhang C, Hollins BC, Soper SA, Feng J. Two-dimensional nitrosylated protein fingerprinting by using poly (methyl methacrylate) microchips. Lab On a Chip. 12: 3362-9. PMID 22766561 DOI: 10.1039/c2lc40132k  1
2012 Hollins BC, Soper SA, Feng J. Enriching carbonylated proteins inside a microchip through the use of oxalyldihydrazide as a crosslinker. Lab On a Chip. 12: 2526-32. PMID 22565136 DOI: 10.1039/c2lc40103g  1
2012 Wang H, Chen HW, Hupert ML, Chen PC, Datta P, Pittman TL, Goettert J, Murphy MC, Williams D, Barany F, Soper SA. Fully integrated thermoplastic genosensor for the highly sensitive detection and identification of multi-drug-resistant tuberculosis. Angewandte Chemie (International Ed. in English). 51: 4349-53. PMID 22431490 DOI: 10.1002/anie.201200732  1
2012 Nesterova IV, Hupert ML, Witek MA, Soper SA. Hydrodynamic shearing of DNA in a polymeric microfluidic device. Lab On a Chip. 12: 1044-7. PMID 22314498 DOI: 10.1039/c2lc21122j  1
2012 Emory JM, Peng Z, Young B, Hupert ML, Rousselet A, Patterson D, Ellison B, Soper SA. Design and development of a field-deployable single-molecule detector (SMD) for the analysis of molecular markers. The Analyst. 137: 87-97. PMID 22005669 DOI: 10.1039/c1an15658f  1
2012 Xia H, Murray K, Soper S, Feng J. Ultra sensitive affinity chromatography on avidin-functionalized PMMA microchip for low abundant post-translational modified protein enrichment. Biomedical Microdevices. 14: 67-81. PMID 21915645 DOI: 10.1007/s10544-011-9586-7  1
2012 Canfield BK, King JK, Robinson WN, Hofmeister WH, Soper SA, Davis LM. Ultrasensitive fluorescence correlation spectroscopy of highly parallelized microfluidic devices Progress in Biomedical Optics and Imaging - Proceedings of Spie. 8228. DOI: 10.1117/12.909515  1
2012 Kotani A, Witek MA, Osiri JK, Wang H, Sinville R, Pincas H, Barany F, Soper SA. EndoV/DNA ligase mutation scanning assay using microchip capillary electrophoresis and dual-color laser-induced fluorescence detection Analytical Methods. 4: 58-64. DOI: 10.1039/c1ay05366c  1
2012 Witek MA, Dharmasiri U, Njoroge SK, Adebiyi MG, Kamande JW, Hupert ML, Barany F, Soper SA. Application of polymer-based microfluidic devices for the selection and manipulation of low-abundant biological cells Ceramic Transactions. 237: 111-122.  1
2012 Wu J, Shao G, Choi J, Uba FI, Soper SA, Park S. Uncoil long DNA molecules by nanoposts array Technical Proceedings of the 2012 Nsti Nanotechnology Conference and Expo, Nsti-Nanotech 2012. 380-383.  1
2011 Njoroge SK, Witek MA, Battle KN, Immethun VE, Hupert ML, Soper SA. Integrated continuous flow polymerase chain reaction and micro-capillary electrophoresis system with bioaffinity preconcentration. Electrophoresis. 32: 3221-32. PMID 22038569 DOI: 10.1002/elps.201100274  1
2011 Wu J, Chantiwas R, Amirsadeghi A, Soper SA, Park S. Complete plastic nanofluidic devices for DNA analysis via direct imprinting with polymer stamps. Lab On a Chip. 11: 2984-9. PMID 21779601 DOI: 10.1039/c1lc20294d  1
2011 Han K, Lee TY, Nikitopoulos DE, Soper SA, Murphy MC. A vertically stacked, polymer, microfluidic point mutation analyzer: rapid high accuracy detection of low-abundance K-ras mutations. Analytical Biochemistry. 417: 211-9. PMID 21771577 DOI: 10.1016/j.ab.2011.06.030  1
2011 Osiri JK, Shadpour H, Witek MA, Soper SA. Integrated multifunctional microfluidics for automated proteome analyses. Topics in Current Chemistry. 304: 261-94. PMID 21678138 DOI: 10.1007/128_2011_152  1
2011 Subramanian B, Kim N, Lee W, Spivak DA, Nikitopoulos DE, McCarley RL, Soper SA. Surface modification of droplet polymeric microfluidic devices for the stable and continuous generation of aqueous droplets. Langmuir : the Acs Journal of Surfaces and Colloids. 27: 7949-57. PMID 21608975 DOI: 10.1021/la200298n  1
2011 Njoroge SK, Chen HW, Witek MA, Soper SA. Integrated microfluidic systems for DNA analysis. Topics in Current Chemistry. 304: 203-60. PMID 21607848 DOI: 10.1007/128_2011_153  1
2011 Chantiwas R, Park S, Soper SA, Kim BC, Takayama S, Sunkara V, Hwang H, Cho YK. Flexible fabrication and applications of polymer nanochannels and nanoslits. Chemical Society Reviews. 40: 3677-702. PMID 21442106 DOI: 10.1039/c0cs00138d  1
2011 Lee J, Soper SA, Murray KK. A solid-phase bioreactor with continuous sample deposition for matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 25: 693-9. PMID 21337630 DOI: 10.1002/rcm.4921  1
2011 Dharmasiri U, Njoroge SK, Witek MA, Adebiyi MG, Kamande JW, Hupert ML, Barany F, Soper SA. High-throughput selection, enumeration, electrokinetic manipulation, and molecular profiling of low-abundance circulating tumor cells using a microfluidic system. Analytical Chemistry. 83: 2301-9. PMID 21319808 DOI: 10.1021/ac103172y  1
2011 Nesterova IV, Bennett CA, Erdem SS, Hammer RP, Deininger PL, Soper SA. Near-IR single fluorophore quenching system based on phthalocyanine (Pc) aggregation and its application for monitoring inhibitor/activator action on a therapeutic target: L1-EN. The Analyst. 136: 1103-5. PMID 21221467 DOI: 10.1039/c0an00782j  1
2011 Sunkara V, Park DK, Hwang H, Chantiwas R, Soper SA, Cho YK. Simple room temperature bonding of thermoplastics and poly(dimethylsiloxane). Lab On a Chip. 11: 962-5. PMID 21152492 DOI: 10.1039/c0lc00272k  1
2011 Kim N, Evans ET, Park DS, Soper SA, Murphy MC, Nikitopoulos DE. Gas-liquid two-phase flows in rectangular polymer micro-channels Experiments in Fluids. 51: 373-393. DOI: 10.1007/s00348-011-1041-2  1
2011 Wu J, Wang H, Kim J, Murphy F, Soper SA, Park S. Influence of nanochannel inlet structure upon DNA capture ratio Asme 2011 International Mechanical Engineering Congress and Exposition, Imece 2011. 11: 643-645.  1
2011 Uba FI, Wu J, Park S, Moldovan D, Novak B, Shin H, Park DK, Cho YK, Kim T, Soper SA. Nanogap electrical detection of single molecules translocating through a nanochannel with transverse nanoelectrodes and funnels populated with an array of nanopillars 15th International Conference On Miniaturized Systems For Chemistry and Life Sciences 2011, Microtas 2011. 1: 401-403.  1
2011 Wang H, Witek M, Park D, Huang J, Barany F, Soper SA. Novel 3D lithographically-prepared solid-phase surfaces made from SU-8 for next generation sequencing 15th International Conference On Miniaturized Systems For Chemistry and Life Sciences 2011, Microtas 2011. 1: 73-75.  1
2010 Li Z, He Q, Ma D, Chen H, Soper SA. Thermoswitchable electrokinetic ion-enrichment/elution based on a poly(N-isopropylacrylamide) hydrogel plug in a microchannel. Analytical Chemistry. 82: 10030-6. PMID 21105674 DOI: 10.1021/ac101768j  1
2010 Peng Z, Soper SA, Pingle MR, Barany F, Davis LM. Ligase detection reaction generation of reverse molecular beacons for near real-time analysis of bacterial pathogens using single-pair fluorescence resonance energy transfer and a cyclic olefin copolymer microfluidic chip. Analytical Chemistry. 82: 9727-35. PMID 21047095 DOI: 10.1021/ac101843n  1
2010 Chantiwas R, Hupert ML, Pullagurla SR, Balamurugan S, Tamarit-López J, Park S, Datta P, Goettert J, Cho YK, Soper SA. Simple replication methods for producing nanoslits in thermoplastics and the transport dynamics of double-stranded DNA through these slits. Lab On a Chip. 10: 3255-64. PMID 20938506 DOI: 10.1039/c0lc00096e  1
2010 De Guzman JM, Soper SA, McCarley RL. Assessment of glycoprotein interactions with 4-[(2-aminoethyl)carbamoyl]phenylboronic acid surfaces using surface plasmon resonance spectroscopy. Analytical Chemistry. 82: 8970-7. PMID 20919681 DOI: 10.1021/ac101911a  1
2010 Okagbare PI, Soper SA. Polymer-based dense fluidic networks for high throughput screening with ultrasensitive fluorescence detection. Electrophoresis. 31: 3074-82. PMID 20872611 DOI: 10.1002/elps.201000209  1
2010 Chen PC, Park DS, You BH, Kim N, Park T, Soper SA, Nikitopoulos DE, Murphy MC. Titer-plate formatted continuous flow thermal reactors: Design and performance of a nanoliter reactor. Sensors and Actuators. B, Chemical. 149: 291-300. PMID 20871807 DOI: 10.1016/j.snb.2010.05.068  1
2010 Dharmasiri U, Witek MA, Adams AA, Soper SA. Microsystems for the capture of low-abundance cells. Annual Review of Analytical Chemistry (Palo Alto, Calif.). 3: 409-31. PMID 20636049 DOI: 10.1146/annurev.anchem.111808.073610  1
2010 Osiri JK, Shadpour H, Soper SA. Ultra-fast two-dimensional microchip electrophoresis using SDS micro-CGE and microemulsion electrokinetic chromatography for protein separations. Analytical and Bioanalytical Chemistry. 398: 489-98. PMID 20614109 DOI: 10.1007/s00216-010-3914-2  1
2010 Njoroge SK, Witek MA, Hupert ML, Soper SA. Microchip electrophoresis of Alu elements for gender determination and inference of human ethnic origin. Electrophoresis. 31: 981-90. PMID 20309932 DOI: 10.1002/elps.200900641  1
2010 Dharmasiri U, Witek MA, Adams AA, Osiri JK, Hupert ML, Bianchi TS, Roelke DL, Soper SA. Enrichment and detection of Escherichia coli O157:H7 from water samples using an antibody modified microfluidic chip. Analytical Chemistry. 82: 2844-9. PMID 20218574 DOI: 10.1021/ac100323k  1
2010 Lee W, Lee YI, Lee J, Davis LM, Deininger P, Soper SA. Cross-talk-free dual-color fluorescence cross-correlation spectroscopy for the study of enzyme activity. Analytical Chemistry. 82: 1401-10. PMID 20073480 DOI: 10.1021/ac9024768  1
2010 Okagbare PI, Emory JM, Datta P, Goettert J, Soper SA. Fabrication of a cyclic olefin copolymer planar waveguide embedded in a multi-channel poly(methyl methacrylate) fluidic chip for evanescence excitation. Lab On a Chip. 10: 66-73. PMID 20024052 DOI: 10.1039/b908759a  1
2010 Lee W, Obubuafo A, Lee YI, Davis LM, Soper SA. Single-pair fluorescence resonance energy transfer (spFRET) for the high sensitivity analysis of low-abundance proteins using aptamers as molecular recognition elements. Journal of Fluorescence. 20: 203-13. PMID 19802688 DOI: 10.1007/s10895-009-0540-5  1
2010 Mudyiwa M, Ndinguri MW, Soper SA, Hammer RP. Microwave assisted solid-phase synthesis of substituted tetraazaporphyrins and a phthalocyanine-peptide conjugate Journal of Porphyrins and Phthalocyanines. 14: 891-903. DOI: 10.1142/S1088424610002744  1
2010 Wu J, Chantiwas R, Soper SA, Park S. Fabrication of cost-effective polymer-based nanofluidic device for single molecular analysis Asme International Mechanical Engineering Congress and Exposition, Proceedings (Imece). 10: 891-897. DOI: 10.1115/IMECE2010-38885  1
2010 Chen PC, Park DS, You BH, Kim N, Park T, Nikitopoulos DE, Soper SA, Murphy MC. A high throughput microfluidic thermal reactor Asme International Mechanical Engineering Congress and Exposition, Proceedings. 2: 273-275. DOI: 10.1115/IMECE2009-13130  1
2010 Fan ZH, Mei Q, Soper S. Microfluidic reactors for bioluminescence detection Asme International Mechanical Engineering Congress and Exposition, Proceedings. 12: 773-778. DOI: 10.1115/IMECE2009-12464  1
2010 Park DS, Singh V, You BH, Kim N, Chen PC, Soper SA, Nikitopoulos DE, Goettert J, Murphy MC. Control of internal stress for high quality nickel large area mold inserts Asme International Mechanical Engineering Congress and Exposition, Proceedings. 12: 263-269. DOI: 10.1115/IMECE2009-11639  1
2010 Park DSW, Chen PC, You BH, Kim N, Park T, Lee TY, Datta P, Desta Y, Soper SA, Nikitopoulos DE, Murphy MC. Titer plate formatted continuous flow thermal reactors for high throughput applications: Fabrication and testing Journal of Micromechanics and Microengineering. 20. DOI: 10.1088/0960-1317/20/5/055003  1
2010 Lee DE, Soper SA, Wang W. Fabrication and mathematical analysis of an electrochemical microactuator (ECM) using electrodes coated with platinum nano-particles Microsystem Technologies. 16: 381-390. DOI: 10.1007/s00542-009-0940-0  1
2010 Rani SD, Park T, You BH, Soper SA, Murphy MC, Nikitopoulos DE. Numerical simulations of misalignment effects in microfluidic interconnects Materials Research Society Symposium Proceedings. 1272: 45-50.  1
2010 Park DS, Wang H, Chen PC, Park T, Kim N, You BH, Nikitopoulos DE, Soper SA, Murphy MC. Passive micro-assembly of a fluidic control chip and a multi-well continuous flow PCR chip for high throughput applications 14th International Conference On Miniaturized Systems For Chemistry and Life Sciences 2010, Microtas 2010. 2: 1226-1228.  1
2009 Lee J, Soper SA, Murray KK. Development of an efficient on-chip digestion system for protein analysis using MALDI-TOF MS. The Analyst. 134: 2426-33. PMID 19918612 DOI: 10.1039/b916556h  1
2009 Erdem SS, Nesterova IV, Soper SA, Hammer RP. Mono-amine functionalized phthalocyanines: microwave-assisted solid-phase synthesis and bioconjugation strategies. The Journal of Organic Chemistry. 74: 9280-6. PMID 19911767 DOI: 10.1021/jo901424v  1
2009 Dharmasiri U, Balamurugan S, Adams AA, Okagbare PI, Obubuafo A, Soper SA. Highly efficient capture and enumeration of low abundance prostate cancer cells using prostate-specific membrane antigen aptamers immobilized to a polymeric microfluidic device. Electrophoresis. 30: 3289-300. PMID 19722212 DOI: 10.1002/elps.200900141  1
2009 Lee J, Soper SA, Murray KK. Microfluidics with MALDI analysis for proteomics--a review. Analytica Chimica Acta. 649: 180-90. PMID 19699392 DOI: 10.1016/j.aca.2009.07.037  1
2009 Lee J, Soper SA, Murray KK. Microfluidic chips for mass spectrometry-based proteomics. Journal of Mass Spectrometry : Jms. 44: 579-93. PMID 19373851 DOI: 10.1002/jms.1585  1
2009 Nesterova IV, Erdem SS, Pakhomov S, Hammer RP, Soper SA. Phthalocyanine dimerization-based molecular beacons using near-IR fluorescence. Journal of the American Chemical Society. 131: 2432-3. PMID 19191492 DOI: 10.1021/ja8088247  1
2009 Okagbare PI, Soper SA. High throughput single molecule detection for monitoring biochemical reactions. The Analyst. 134: 97-106. PMID 19082181 DOI: 10.1039/b816383a  1
2009 Chen PC, Park DS, You BH, Kim N, Park T, Desta Y, Park S, Nikitopoulos DE, Soper SA, Murphy MC. A thermal system for a high throughput continuous flow polymerase chain reaction device (CFPCR) Asme International Mechanical Engineering Congress and Exposition, Proceedings. 13: 313-317. DOI: 10.1115/IMECE2008-68975  1
2009 Byoung HY, Park DS, Chen PC, Rani SD, Nikitopoulos DE, Soper SA, Murphy MC. Assembly tolerance analysis for injection molded modular, polymer microfluidic devices Asme International Mechanical Engineering Congress and Exposition, Proceedings. 13: 803-809. DOI: 10.1115/IMECE2008-68143  1
2009 Chen PC, Wang H, Park DS, Park S, Nikitopoulos DE, Soper SA, Murphy MC. Protein adsorption in a continuous flow microchannel environment Asme International Mechanical Engineering Congress and Exposition, Proceedings. 2: 249-253. DOI: 10.1115/IMECE2008-68094  1
2009 Kim N, Murphy MC, Soper SA, Nikitopoulos DE. Liquid-liquid segmented flows in polymer microfluidic channels Proceedings of the 7th International Conference On Nanochannels, Microchannels, and Minichannels 2009, Icnmm2009. 1155-1165. DOI: 10.1115/ICNMM2009-82277  1
2009 Maha A, Palaparthy V, Soper SA, Murphy MC, Nikitopoulos DE. Optimized high-aspect-ratio diffusional micromixers 2008 Proceedings of the Asme Fluids Engineering Division Summer Conference, Fedsm 2008. 2: 555-556. DOI: 10.1115/FEDSM2008-55294  1
2009 Kim N, Evans ET, Soper SA, Murphy MC, Nikitopoulos DE. Investigation of two-phase flow in rectangular micro-channels 2008 Proceedings of the Asme Fluids Engineering Division Summer Conference, Fedsm 2008. 2: 451-461. DOI: 10.1115/FEDSM2008-55037  1
2009 Lee W, Kim N, Balamurugan S, Nikitopoulos DE, Murphy MC, Soper SA. Liquid-liquid segmented flows in polymer microfluidic channels for high throughput studies of enzyme activity using dual-color fluorescence crosscorrelation spectroscopy (FCCS) Proceedings of Conference, Microtas 2009 - the 13th International Conference On Miniaturized Systems For Chemistry and Life Sciences. 952-954.  1
2009 Chantiwas R, Hupert ML, López JT, Datta P, Gottert J, Novak B, Moldovan D, Jha S, Park S, Murphy MC, Nikitopoulos DE, Soper SA. Transport of single molecules through nanochannels: A novel approach to DNA sequencing Proceedings of Conference, Microtas 2009 - the 13th International Conference On Miniaturized Systems For Chemistry and Life Sciences. 177-179.  1
2009 Chen PC, Park DS, You BH, Kim N, Park T, Soper SA, Nikitopoulos DE, Murphy MC. A disposable high throughput microfluidic thermal reactor Proceedings of Conference, Microtas 2009 - the 13th International Conference On Miniaturized Systems For Chemistry and Life Sciences. 639-641.  1
2008 Bolivar JG, Soper SA, McCarley RL. Nitroavidin as a ligand for the surface capture and release of biotinylated proteins. Analytical Chemistry. 80: 9336-42. PMID 19551994 DOI: 10.1021/ac801750d  1
2008 Osiri JK, Shadpour H, Park S, Snowden BC, Chen ZY, Soper SA. Generating high peak capacity 2-D maps of complex proteomes using PMMA microchip electrophoresis. Electrophoresis. 29: 4984-92. PMID 19130578 DOI: 10.1002/elps.200800496  1
2008 Sinville R, Coyne J, Meagher RJ, Cheng YW, Barany F, Barron A, Soper SA. Ligase detection reaction for the analysis of point mutations using free-solution conjugate electrophoresis in a polymer microfluidic device. Electrophoresis. 29: 4751-60. PMID 19053073 DOI: 10.1002/elps.200800197  1
2008 Balamurugan S, Obubuafo A, McCarley RL, Soper SA, Spivak DA. Effect of linker structure on surface density of aptamer monolayers and their corresponding protein binding efficiency. Analytical Chemistry. 80: 9630-4. PMID 18989937 DOI: 10.1021/ac8009559  1
2008 Obubuafo A, Balamurugan S, Shadpour H, Spivak D, McCarley RL, Soper SA. Poly(methyl methacrylate) microchip affinity capillary gel electrophoresis of aptamer-protein complexes for the analysis of thrombin in plasma. Electrophoresis. 29: 3436-45. PMID 18702051 DOI: 10.1002/elps.200700854  1
2008 Mei Q, Xia Z, Xu F, Soper SA, Fan ZH. Fabrication of microfluidic reactors and mixing studies for luciferase detection. Analytical Chemistry. 80: 6045-50. PMID 18593194 DOI: 10.1021/ac800843v  1
2008 Adams AA, Okagbare PI, Feng J, Hupert ML, Patterson D, Göttert J, McCarley RL, Nikitopoulos D, Murphy MC, Soper SA. Highly efficient circulating tumor cell isolation from whole blood and label-free enumeration using polymer-based microfluidics with an integrated conductivity sensor. Journal of the American Chemical Society. 130: 8633-41. PMID 18557614 DOI: 10.1021/ja8015022  1
2008 Erdem SS, Nesterova IV, Soper SA, Hammer RP. Solid-phase synthesis of asymmetrically substituted "AB3-type" phthalocyanines. The Journal of Organic Chemistry. 73: 5003-7. PMID 18510363 DOI: 10.1021/jo800536v  1
2008 Lee J, Musyimi HK, Soper SA, Murray KK. Development of an automated digestion and droplet deposition microfluidic chip for MALDI-TOF MS. Journal of the American Society For Mass Spectrometry. 19: 964-72. PMID 18479934 DOI: 10.1016/j.jasms.2008.03.015  1
2008 Emory JM, Soper SA. Charge-coupled device operated in a time-delayed integration mode as an approach to high-throughput flow-based single molecule analysis. Analytical Chemistry. 80: 3897-903. PMID 18412372 DOI: 10.1021/ac800447x  1
2008 Wang Y, Chen H, He Q, Soper SA. A high-performance polycarbonate electrophoresis microchip with integrated three-electrode system for end-channel amperometric detection. Electrophoresis. 29: 1881-8. PMID 18393335 DOI: 10.1002/elps.200700377  1
2008 Witek MA, Hupert ML, Park DS, Fears K, Murphy MC, Soper SA. 96-well polycarbonate-based microfluidic titer plate for high-throughput purification of DNA and RNA. Analytical Chemistry. 80: 3483-91. PMID 18355091 DOI: 10.1021/ac8002352  1
2008 Chen PC, Nikitopoulos DE, Soper SA, Murphy MC. Temperature distribution effects on micro-CFPCR performance. Biomedical Microdevices. 10: 141-52. PMID 17896180 DOI: 10.1007/s10544-007-9119-6  1
2008 Balamurugan S, Obubuafo A, Soper SA, Spivak DA. Surface immobilization methods for aptamer diagnostic applications. Analytical and Bioanalytical Chemistry. 390: 1009-21. PMID 17891385 DOI: 10.1007/s00216-007-1587-2  1
2008 Park DS, Hupert ML, Witek MA, You BH, Datta P, Guy J, Lee JB, Soper SA, Nikitopoulos DE, Murphy MC. A titer plate-based polymer microfluidic platform for high throughput nucleic acid purification. Biomedical Microdevices. 10: 21-33. PMID 17659445 DOI: 10.1007/s10544-007-9106-y  1
2008 Park T, Jensen T, Park D, Guy J, Datta P, Soper SA, Murphy MC. Capture of very rare circulating tumor cells for human breast cancer diagnosis Asme International Mechanical Engineering Congress and Exposition, Proceedings. 11: 131-137. DOI: 10.1115/IMECE2007-42425  1
2008 Lee TY, Nikitopoulos DE, Park DS, Soper SA, Murphy MC. Design and fabrication of a ligase detection reaction (LDR) microchip with an integrated passive micromixer Asme International Mechanical Engineering Congress and Exposition, Proceedings. 11: 125-130. DOI: 10.1115/IMECE2007-42216  1
2008 Chen PC, You BH, Park DS, Park S, Guy J, Nikitopoulos DE, Soper SA, Murphy MC. Replication of reliable assembly features for polymer modular microfluidic systems Asme International Mechanical Engineering Congress and Exposition, Proceedings. 11: 119-124. DOI: 10.1115/IMECE2007-42206  1
2008 Kim N, Evans ET, Park DS, Nikitopoulos DE, Soper SA, Murphy MC. Gas-liquid two-phase flow in hot embossed square microchannels Asme International Mechanical Engineering Congress and Exposition, Proceedings. 11: 427-436. DOI: 10.1115/IMECE2007-42158  1
2008 Park DS, Chen PC, You BH, Kim N, Park T, Datta P, Desta Y, Soper SA, Nikitopoulos DE, Murphy MC. Optimization of the geometry for continuous flow PCR devices in a titer plate-based PCR multi-reactor platform Asme International Mechanical Engineering Congress and Exposition, Proceedings. 11: 113-118. DOI: 10.1115/IMECE2007-42135  1
2008 Menard LD, Soper SA, Braun KL, Huang C, Ramsey JM. Analysis of single DNA molecules translocating through nanochannels fabricated in SiO2 12th International Conference On Miniaturized Systems For Chemistry and Life Sciences - the Proceedings of Microtas 2008 Conference. 847-849.  1
2008 Hupert ML, Wang H, Chen HW, Stryjewski W, Patterson D, Witek MA, Datta P, Goettert J, Murphy MC, Soper SA. A field-deployable system for automated molecular testing using modular microfludics 12th International Conference On Miniaturized Systems For Chemistry and Life Sciences - the Proceedings of Microtas 2008 Conference. 1946-1948.  1
2008 Chen PC, Park DS, You BH, Kim N, Park T, Datta P, Desta Y, Soper SA, Nikitopoulos DE, Murphy MC. Design and performance of a rapid, nanoliter, continuous flow polymerase chain reactor for a high throughput microsystem 12th International Conference On Miniaturized Systems For Chemistry and Life Sciences - the Proceedings of Microtas 2008 Conference. 619-621.  1
2008 Emory JM, Peng Z, Crawford-Drake F, Chen PC, Murphy MC, Soper SA. A compact microfluidic system with an integrated optical system for singlemolecule detection via fluorescence resonance energy transfer for realtime molecular analyses 12th International Conference On Miniaturized Systems For Chemistry and Life Sciences - the Proceedings of Microtas 2008 Conference. 402-404.  1
2008 Okagbare PI, Gottert J, Datta P, Singh V, Soper SA. Polymer-based dense fluidic networks for High Throughput Screening (HTS) with ultrasensitive fluorescence 12th International Conference On Miniaturized Systems For Chemistry and Life Sciences - the Proceedings of Microtas 2008 Conference. 594-596.  1
2008 Njoroge SK, Witek MA, Hupert ML, Coyne J, Barron A, Batzer MA, Soper SA. Human identification using ALUS analyzed via an integrated microfluidic system with multicolor fluorescence and microchip free solution conjugate electrophoresis 12th International Conference On Miniaturized Systems For Chemistry and Life Sciences - the Proceedings of Microtas 2008 Conference. 946-948.  1
2007 Nesterova IV, Verdree VT, Pakhomov S, Strickler KL, Allen MW, Hammer RP, Soper SA. Metallo-phthalocyanine near-IR fluorophores: oligonucleotide conjugates and their applications in PCR assays. Bioconjugate Chemistry. 18: 2159-68. PMID 18030995 DOI: 10.1021/bc700233w  1
2007 Chen G, McCandless GT, McCarley RL, Soper SA. Integration of large-area polymer nanopillar arrays into microfluidic devices using in situ polymerization cast molding. Lab On a Chip. 7: 1424-7. PMID 17960266 DOI: 10.1039/b713324c  1
2007 Xu F, Datta P, Wang H, Gurung S, Hashimoto M, Wei S, Goettert J, McCarley RL, Soper SA. Polymer microfluidic chips with integrated waveguides for reading microarrays. Analytical Chemistry. 79: 9007-13. PMID 17949012 DOI: 10.1021/ac7016597  1
2007 Chen G, Soper SA, McCarley RL. Free-standing, erect ultrahigh-aspect-ratio polymer nanopillar and nanotube ensembles. Langmuir : the Acs Journal of Surfaces and Colloids. 23: 11777-81. PMID 17929951 DOI: 10.1021/la701502m  1
2007 Hashimoto M, Barany F, Xu F, Soper SA. Serial processing of biological reactions using flow-through microfluidic devices: coupled PCR/LDR for the detection of low-abundant DNA point mutations. The Analyst. 132: 913-21. PMID 17710267 DOI: 10.1039/b700071e  1
2007 Sinville R, Soper SA. High resolution DNA separations using microchip electrophoresis. Journal of Separation Science. 30: 1714-28. PMID 17623451 DOI: 10.1002/jssc.200700150  1
2007 Verdree VT, Pakhomov S, Su G, Allen MW, Countryman AC, Hammer RP, Soper SA. Water soluble metallo-phthalocyanines: the role of the functional groups on the spectral and photophysical properties. Journal of Fluorescence. 17: 547-63. PMID 17574523 DOI: 10.1007/s10895-007-0210-4  1
2007 Llopis SL, Osiri J, Soper SA. Surface modification of poly(methyl methacrylate) microfluidic devices for high-resolution separations of single-stranded DNA. Electrophoresis. 28: 984-93. PMID 17309052 DOI: 10.1002/elps.200600435  1
2007 Situma C, Moehring AJ, Noor MA, Soper SA. Immobilized molecular beacons: a new strategy using UV-activated poly(methyl methacrylate) surfaces to provide large fluorescence sensitivities for reporting on molecular association events. Analytical Biochemistry. 363: 35-45. PMID 17300739 DOI: 10.1016/j.ab.2006.12.029  1
2007 Sibrian-Vazquez M, Ortiz J, Nesterova IV, Fernandez-Lazaro F, Sastre-Santos A, Soper SA, Vicente MG. Synthesis and properties of cell-targeted Zn(II)-phthalocyanine-peptide conjugates. Bioconjugate Chemistry. 18: 410-20. PMID 17279788 DOI: 10.1021/bc060297b  1
2007 Shadpour H, Hupert ML, Patterson D, Liu C, Galloway M, Stryjewski W, Goettert J, Soper SA. Multichannel microchip electrophoresis device fabricated in polycarbonate with an integrated contact conductivity sensor array. Analytical Chemistry. 79: 870-8. PMID 17263312 DOI: 10.1021/ac0612168  1
2007 Lee DE, Soper S, Wang W. Fabrication of a microfluidic system with integrated electrochemical pump and valves Proceedings of Spie - the International Society For Optical Engineering. 6465. DOI: 10.1117/12.713916  1
2007 You BH, Park DS, Chen PC, Caceres WM, Nikitopoulos DE, Soper SA, Murphy MC. Dimensional and locational integrity in the replication of polymeric microdevices 2007 Proceedings of the Asme Interpack Conference, Ipack 2007. 2: 955-959. DOI: 10.1115/IPACK2007-33482  1
2007 Chen PC, Mitchell MW, Nikitopoulos DE, Soper SA, Murphy MC. Assessment and improvement of the thermal performance of a polycarbonate micro Continuous Flow Polymerase Chain Reactor (CFPCR) 2007 Proceedings of the Asme Interpack Conference, Ipack 2007. 1: 129-135. DOI: 10.1115/IPACK2007-33330  1
2007 Chen G, McCarley RL, Soper SA, Situma C, Bolivar JG. Functional template-derived poly(methyl methacrylate) nanopillars for solid-phase biological reactions Chemistry of Materials. 19: 3855-3857. DOI: 10.1021/cm0702870  1
2007 Yang R, Soper SA, Wang W. A new UV lithography photoresist based on composite of EPON resins 165 and 154 for fabrication of high-aspect-ratio microstructures Sensors and Actuators, a: Physical. 135: 625-636. DOI: 10.1016/j.sna.2006.09.009  1
2007 Hupert ML, Guy WJ, Llopis SD, Shadpour H, Rani S, Nikitopoulos DE, Soper SA. Evaluation of micromilled metal mold masters for the replication of microchip electrophoresis devices Microfluidics and Nanofluidics. 3: 1-11. DOI: 10.1007/s10404-006-0091-x  1
2007 Zhu L, Soper SA. Ultra sensitive time-resolved near-IR fluorescence for multiplexed bioanalysis Chemical Analysis. 172: 141-168. DOI: 10.1002/9780470119501.ch7  1
2007 Park DS, Hupert ML, Witek M, Guy J, Datta P, You BH, Soper SA, Murphy MC. A 96-well SPRI reactor in a Photo-activated Polycarbonate (PPC) microfluidic chip Proceedings of the Ieee International Conference On Micro Electro Mechanical Systems (Mems). 433-436.  1
2006 Yang R, Soper SA, Wang W. Microfabrication of pre-aligned fiber bundle couplers using ultraviolet lithography of SU-8. Sensors and Actuators. a, Physical. 127: 123-130. PMID 18846244 DOI: 10.1016/j.sna.2005.11.007  1
2006 Dovichi NJ, Soper SA. Cost-benefit analysis of the RFA. Science (New York, N.Y.). 314: 1682. PMID 17170275 DOI: 10.1126/science.314.5806.1682a  1
2006 Wang H, Chen J, Zhu L, Shadpour H, Hupert ML, Soper SA. Continuous flow thermal cycler microchip for DNA cycle sequencing. Analytical Chemistry. 78: 6223-31. PMID 16944905 DOI: 10.1021/ac060568b  1
2006 Situma C, Hashimoto M, Soper SA. Merging microfluidics with microarray-based bioassays. Biomolecular Engineering. 23: 213-31. PMID 16905357 DOI: 10.1016/j.bioeng.2006.03.002  1
2006 Balamurugan S, Obubuafo A, Soper SA, McCarley RL, Spivak DA. Designing highly specific biosensing surfaces using aptamer monolayers on gold. Langmuir : the Acs Journal of Surfaces and Colloids. 22: 6446-53. PMID 16800712 DOI: 10.1021/la060222w  1
2006 Witek MA, Llopis SD, Wheatley A, McCarley RL, Soper SA. Purification and preconcentration of genomic DNA from whole cell lysates using photoactivated polycarbonate (PPC) microfluidic chips. Nucleic Acids Research. 34: e74. PMID 16757572 DOI: 10.1093/nar/gkl146  1
2006 Shadpour H, Soper SA. Two-dimensional electrophoretic separation of proteins using poly(methyl methacrylate) microchips. Analytical Chemistry. 78: 3519-27. PMID 16737203 DOI: 10.1021/ac0600398  1
2006 Kong Y, Chen H, Wang Y, Soper SA. Fabrication of a gold microelectrode for amperometric detection on a polycarbonate electrophoresis chip by photodirected electroless plating. Electrophoresis. 27: 2940-50. PMID 16688700 DOI: 10.1002/elps.200500750  1
2006 Shadpour H, Musyimi H, Chen J, Soper SA. Physiochemical properties of various polymer substrates and their effects on microchip electrophoresis performance. Journal of Chromatography. A. 1111: 238-51. PMID 16569584 DOI: 10.1016/j.chroma.2005.08.083  1
2006 Hashimoto M, Barany F, Soper SA. Polymerase chain reaction/ligase detection reaction/hybridization assays using flow-through microfluidic devices for the detection of low-abundant DNA point mutations. Biosensors & Bioelectronics. 21: 1915-23. PMID 16488597 DOI: 10.1016/j.bios.2006.01.014  1
2006 Soper SA, Brown K, Ellington A, Frazier B, Garcia-Manero G, Gau V, Gutman SI, Hayes DF, Korte B, Landers JL, Larson D, Ligler F, Majumdar A, Mascini M, Nolte D, et al. Point-of-care biosensor systems for cancer diagnostics/prognostics. Biosensors & Bioelectronics. 21: 1932-42. PMID 16473506 DOI: 10.1016/j.bios.2006.01.006  1
2006 Lee DE, Soper SA, Wang W. Fabrication and test of an electrochemical microactutor Proceedings of Spie - the International Society For Optical Engineering. 6112. DOI: 10.1117/12.650850  1
2006 Yang R, Soper SA, Wang W. Microfabrication and test of pre-aligned fiber bundle couplers with integrated microlens array Proceedings of Spie - the International Society For Optical Engineering. 6113. DOI: 10.1117/12.650177  1
2006 Hupert ML, Jason Guy W, Llopis SD, Situma C, Rani S, Nikitopoulos DE, Soper SA. High-precision micromilling for low-cost fabrication of metal mold masters Proceedings of Spie - the International Society For Optical Engineering. 6112. DOI: 10.1117/12.647135  1
2006 Datta P, Xu F, Gurung S, Soper SA, Goettert J. Polymeric waveguides for orthogonal near surface fluorescent excitation Proceedings of Spie - the International Society For Optical Engineering. 6112. DOI: 10.1117/12.647014  1
2006 You BH, Chen PC, Guy J, Datta P, Nikitopoulos DE, Soper SA, Murphy MC. Passive alignment structures in modular, polymer microfluidic devices American Society of Mechanical Engineers, Micro-Electro Mechanical Systems Division, (Publications) Mems. DOI: 10.1115/IMECE2006-16100  1
2006 Rani SD, Soper SA, Nikitopoulos DE, Murphy MC. Simulation of electroosmotic and pressure driven flows in microfluidic interconnects American Society of Mechanical Engineers, Micro-Electro Mechanical Systems Division, (Publications) Mems. DOI: 10.1115/IMECE2006-15388  1
2006 Elmajdoub N, Nikitopoulos DE, Soper SA, Murphy MC. Design aspects and simulations of a modified micro-scale electrophoretron American Society of Mechanical Engineers, Micro-Electro Mechanical Systems Division, (Publications) Mems. DOI: 10.1115/IMECE2006-15365  1
2006 Park DS, Hupert M, Guy J, Datta P, Lee JB, Witek M, You BH, Soper SA, Nikitopoulos DE, Murphy MC. Microtiter plate-based microfluidic platforms: Sealing, leakage testing, and performance of a 96-well SPRI device American Society of Mechanical Engineers, Micro-Electro Mechanical Systems Division, (Publications) Mems. DOI: 10.1115/IMECE2006-15275  1
2006 You BH, Park DS, Mock CW, Caceres WM, Nikitopoulos DE, Soper SA, Murphy MC. Tolerance variation and passive alignment in modular, polymer microfluidic devices American Society of Mechanical Engineers, Micro-Electro Mechanical Systems Division, (Publications) Mems. DOI: 10.1115/IMECE2006-15258  1
2006 Yang R, Wang W, Soper SA. A new negative-tone, UV lithography photoresist for fabrication of ultra-high-aspect-ratio microstructures American Society of Mechanical Engineers, Micro-Electro Mechanical Systems Division, (Publications) Mems. DOI: 10.1115/IMECE2006-14713  1
2006 Wei S, Soper SA, McCarley RL. A novel biosensor system on microfluidic platform for early diagnosis of breast cancer Aiche Annual Meeting, Conference Proceedings 1
2006 Emory J, Yang R, Wang W, Soper SA. A discontinuous, embedded waveguide and microlens system for multiplex single molecule detection in polymer microfluidic systems Micro Total Analysis Systems - Proceedings of Microtas 2006 Conference: 10th International Conference On Miniaturized Systems For Chemistry and Life Sciences. 1223-1225.  1
2006 Sinville R, Llopis S, Pincas H, Barany F, Soper SA. Microchip-based electrophoretic analysis of low abundant unknown mutations using site-specific nicking and ligation enzymes Micro Total Analysis Systems - Proceedings of Microtas 2006 Conference: 10th International Conference On Miniaturized Systems For Chemistry and Life Sciences. 1450-1452.  1
2006 Witek MA, Chen G, Shadpour H, Khaterpal I, Prockop D, Gregory CA, McCarley RL, Soper SA. Integrated microfluidic system for the processing of membrane proteins isolated from stem cells Micro Total Analysis Systems - Proceedings of Microtas 2006 Conference: 10th International Conference On Miniaturized Systems For Chemistry and Life Sciences. 1456-1458.  1
2006 Chen PC, Chen J, Nikitopoulos DE, Soper SA, Murphy MC. Performance of an electrokinetic shuttle PCR polymerase Chain reactor American Society of Mechanical Engineers, Micro-Electro Mechanical Systems Division, (Publications) Mems 1
2006 Chen G, Situma C, Soper SA, McCarley RL. Three-dimensional biologically-active nanostructured architectures in polymer-based microfluidic devices for biomarker detection Micro Total Analysis Systems - Proceedings of Microtas 2006 Conference: 10th International Conference On Miniaturized Systems For Chemistry and Life Sciences. 1205-1207.  1
2006 Musyimi HK, Shadpour H, Chen G, McCarley RL, Murray KK, Soper SA. Integrated microfluidic system for proteomics using mixed-scale structures and MALDI-TOF-MS Micro Total Analysis Systems - Proceedings of Microtas 2006 Conference: 10th International Conference On Miniaturized Systems For Chemistry and Life Sciences. 1570-1572.  1
2005 Wei S, Vaidya B, Patel AB, Soper SA, McCarley RL. Photochemically patterned poly(methyl methacrylate) surfaces used in the fabrication of microanalytical devices. The Journal of Physical Chemistry. B. 109: 16988-96. PMID 16853163 DOI: 10.1021/jp051550s  1
2005 Musyimi HK, Guy J, Narcisse DA, Soper SA, Murray KK. Direct coupling of polymer-based microchip electrophoresis to online MALDI-MS using a rotating ball inlet. Electrophoresis. 26: 4703-10. PMID 16358254 DOI: 10.1002/elps.200500317  1
2005 Soper SA, Hashimoto M, Situma C, Murphy MC, McCarley RL, Cheng YW, Barany F. Fabrication of DNA microarrays onto polymer substrates using UV modification protocols with integration into microfluidic platforms for the sensing of low-abundant DNA point mutations. Methods (San Diego, Calif.). 37: 103-13. PMID 16199178 DOI: 10.1016/j.ymeth.2005.07.004  1
2005 Hashimoto M, Hupert ML, Murphy MC, Soper SA, Cheng YW, Barany F. Ligase detection reaction/hybridization assays using three-dimensional microfluidic networks for the detection of low-abundant DNA point mutations. Analytical Chemistry. 77: 3243-55. PMID 15889915 DOI: 10.1021/ac048184d  1
2005 Situma C, Wang Y, Hupert M, Barany F, McCarley RL, Soper SA. Fabrication of DNA microarrays onto poly(methyl methacrylate) with ultraviolet patterning and microfluidics for the detection of low-abundant point mutations Analytical Biochemistry. 340: 123-135. PMID 15802138 DOI: 10.1016/j.ab.2005.01.044  1
2005 McCarley RL, Vaidya B, Wei S, Smith AF, Patel AB, Feng J, Murphy MC, Soper SA. Resist-free patterning of surface architectures in polymer-based microanalytical devices. Journal of the American Chemical Society. 127: 842-3. PMID 15656615 DOI: 10.1021/ja0454135  1
2005 Chen J, Wabuyele M, Chen H, Patterson D, Hupert M, Shadpour H, Nikitopoulos D, Soper SA. Electrokinetically synchronized polymerase chain reaction microchip fabricated in polycarbonate Analytical Chemistry. 77: 658-666. PMID 15649068 DOI: 10.1021/ac048758e  1
2005 Yang R, Soper SA, Wang W. Fabrication of out-of-plane refractive concave and convex microlens arrays Progress in Biomedical Optics and Imaging - Proceedings of Spie. 5717: 134-141. DOI: 10.1117/12.601832  1
2005 Yang R, Soper SA, Wang W. Microfabrication of an integrated SU-8 waveguide with an imbedded focusing lens for application in Single Molecule Detection (SMD) Progress in Biomedical Optics and Imaging - Proceedings of Spie. 5718: 54-59. DOI: 10.1117/12.591956  1
2005 Yang R, Wang W, Soper SA. Out-of-plane microlens array fabricated using ultraviolet lithography Applied Physics Letters. 86: 1-3. DOI: 10.1063/1.1901829  1
2005 Chen G, Bolivar JG, Soper SA, McCarley RL. Highly efficient protein capture and enzyme reactor beds based on ultra-high-aspect- Ratio nanostructures (uharns) Micro Total Analysis Systems - Proceedings of Microtas 2005 Conference: 9th International Conference On Miniaturized Systems For Chemistry and Life Sciences. 1: 1261-1263.  1
2004 Hashimoto M, Chen PC, Mitchell MW, Nikitopoulos DE, Soper SA, Murphy MC. Rapid PCR in a continuous flow device. Lab On a Chip. 4: 638-45. PMID 15570378 DOI: 10.1039/b406860b  1
2004 Llopis SD, Stryjewski W, Soper SA. Near-infrared time-resolved fluorescence lifetime determinations in poly(methylmethacrylate) microchip electrophoresis devices Electrophoresis. 25: 3810-3819. PMID 15565677 DOI: 10.1002/elps.200406054  1
2004 Witek MA, Wei S, Vaidya B, Adams AA, Zhu L, Stryjewski W, McCarley RL, Soper SA. Cell transport via electromigration in polymer-based microfluidic devices Lab On a Chip - Miniaturisation For Chemistry and Biology. 4: 464-472. PMID 15472730 DOI: 10.1039/b317093d  1
2004 Musyimi HK, Narcisse DA, Zhang X, Stryjewski W, Soper SA, Murray KK. Online CE-MALDI-TOF MS using a rotating ball interface. Analytical Chemistry. 76: 5968-73. PMID 15456323 DOI: 10.1021/ac0489723  1
2004 Zhu L, Stryjewski WJ, Soper SA. Multiplexed fluorescence detection in microfabricated devices with both time-resolved and spectral-discrimination capabilities using near-infrared fluorescence Analytical Biochemistry. 330: 206-218. PMID 15203326 DOI: 10.1016/j.ab.2004.03.047  1
2004 Thomas G, Sinville R, Sutton S, Farquar H, Hammer RP, Soper SA, Cheng YW, Barany F. Capillary and microelectrophoretic separations of ligase detection reaction products produced from low-abundant point mutations in genomic DNA. Electrophoresis. 25: 1668-77. PMID 15188256 DOI: 10.1002/elps.200405886  1
2004 Maha A, Barrett DO, Nikitopoulos DE, Soper SA, Murphy MC. Simulation and Design of Micro-mixers for Microfluidic Devices Proceedings of Spie - the International Society For Optical Engineering. 5345: 183-193. DOI: 10.1117/12.530788  1
2004 Feng J, Soper SA, McCarley RL, Murphy MC. Separation of breast cancer cells from peripherally circulating blood using antibodies fixed in micro-channels Progress in Biomedical Optics and Imaging - Proceedings of Spie. 5: 278-293. DOI: 10.1117/12.529748  1
2004 Barrett DO, Maha A, Wang Y, Soper SA, Nikitopoulos DE, Murphy MC. Design of a Microfabricated Device for Ligase Detection Reaction (LDR) Proceedings of Spie - the International Society For Optical Engineering. 5345: 78-88. DOI: 10.1117/12.524681  1
2004 Barrett DO, Maha A, Wang Y, Soper SA, Nikitopoulos DE, Murphy MC. Design of a microfabricated device for the Ligase Detection Reaction (LDR) American Society of Mechanical Engineers, Micro-Electro Mechanical Systems Division, (Publications) Mems. 311-319. DOI: 10.1115/IMECE2004-62111  1
2004 Shadpour H, Soper SA. Multi-dimensional microchip electrophoresis of proteins Aiche Annual Meeting, Conference Proceedings. 1933-1939.  1
2003 Xu Y, Vaidya B, Patel AB, Ford SM, McCarley RL, Soper SA. Solid-phase reversible immobilization in microfluidic chips for the purification of dye-labeled DNA sequencing fragments Analytical Chemistry. 75: 2975-2984. PMID 12964741 DOI: 10.1021/ac030031n  1
2003 Zhu L, Stryjewski W, Lassiter S, Soper SA. Fluorescence multiplexing with time-resolved and spectral discrimination using a near-IR detector Analytical Chemistry. 75: 2280-2291. PMID 12918968 DOI: 10.1021/ac020776d  1
2003 Wabuyele MB, Farquar H, Stryjewski W, Hammer RP, Soper SA, Cheng YW, Barany F. Approaching real-time molecular diagnostics: single-pair fluorescence resonance energy transfer (spFRET) detection for the analysis of low abundant point mutations in K-ras oncogenes. Journal of the American Chemical Society. 125: 6937-45. PMID 12783546 DOI: 10.1021/ja034716g  1
2003 Wang Y, Vaidya B, Farquar HD, Stryjewski W, Hammer RP, McCarley RL, Soper SA, Cheng YW, Barany F. Microarrays assembled in microfluidic chips fabricated from poly(methyl methacrylate) for the detection of low-abundant DNA mutations. Analytical Chemistry. 75: 1130-40. PMID 12641233 DOI: 10.1021/ac020683w  1
2003 Hupert ML, Witek MA, Wang Y, Mitchell MW, Liu Y, Bejat Y, Nikitopoulos DE, Goettert J, Murphy MC, Soper SA. Polymer-based microfluidic devices for biomedical applications Proceedings of Spie - the International Society For Optical Engineering. 4982: 52-64. DOI: 10.1117/12.480771  1
2003 Wabuyele MB, Farquar H, Stryjewski W, Hammer RP, Soper SA, Cheng YW, Barany F. Detection of low abundant mutations in DNA using single molecule FRET and ligase detection reactions Proceedings of Spie - the International Society For Optical Engineering. 4962: 58-69. DOI: 10.1117/12.478916  1
2003 Mitchell MW, Liu X, Bejat Y, Nikitopoulos DE, Soper SA, Murphy MC. Modeling and validation of a molded polycarbonate continuous flow polymerase chain reaction device Proceedings of Spie - the International Society For Optical Engineering. 4982: 83-98. DOI: 10.1117/12.478142  1
2002 Hammer RP, Owens CV, Hwang SH, Sayes CM, Soper SA. Asymmetrical, water-soluble phthalocyanine dyes for covalent labeling of oligonucleotides. Bioconjugate Chemistry. 13: 1244-52. PMID 12440859 DOI: 10.1021/bc0155869  1
2002 Galloway MM, Soper SA. Contact conductivity detection of polymerase chain reaction products analyzed by reverse-phase ion pair microcapillary electrochromatography Electrophoresis. 23: 3760-3768. PMID 12432539 DOI: 10.1002/1522-2683(200211)23:21<3760::AID-ELPS3760>3.0.CO;2-V  1
2002 Vaidya B, Soper SA, McCarley RL. Surface modification and characterization of microfabricated poly(carbonate) devices: Manipulation of electroosmotic flow Analyst. 127: 1289-1292. PMID 12430597 DOI: 10.1039/b205801b  1
2002 Thomas GA, Farquar HD, Sutton S, Hammer RP, Soper SA. BioMEMS using electrophoresis for the analysis of genetic mutations. Expert Review of Molecular Diagnostics. 2: 429-47. PMID 12271815 DOI: 10.1586/14737159.2.5.429  1
2002 Lassiter SJ, Stryjewski W, Owens CV, Flanagan JH, Hammer RP, Khan S, Soper SA. Optimization of sequencing conditions using near-infrared lifetime identification methods in capillary gel electrophoresis. Electrophoresis. 23: 1480-9. PMID 12116159 DOI: 10.1002/1522-2683(200205)23:10<1480::AID-ELPS1480>3.0.CO;2-F  1
2002 Galloway M, Stryjewski W, Henry A, Ford SM, Llopis S, McCarley RL, Soper SA. Contact conductivity detection in poly(methyl methacylate)-based microfluidic devices for analysis of mono- and polyanionic molecules Analytical Chemistry. 74: 2407-2415. PMID 12038768 DOI: 10.1021/ac011058e  1
2002 Stryjewski WJ, Soper SA, Lassiter S, Davis L. Multiplexed analysis using time-resolved near-IR fluorescence for the detection of genomic material Proceedings of Spie - the International Society For Optical Engineering. 4626: 201-209. DOI: 10.1117/12.472082  1
2002 Soper SA, Henry AC, Vaidya B, Galloway M, Wabuyele M, McCarley RL. Surface modification of polymer-based microfluidic devices Analytica Chimica Acta. 470: 87-99. DOI: 10.1016/S0003-2670(02)00356-2  1
2001 Wabuyele MB, Ford SM, Stryjewski W, Barrow J, Soper SA. Single molecule detection of double-stranded DNA in poly(methylmethacrylate) and polycarbonate microfluidic devices. Electrophoresis. 22: 3939-48. PMID 11700724 DOI: 10.1002/1522-2683(200110)22:18<3939::AID-ELPS3939>3.0.CO;2-9  1
2001 Meng Z, Qi S, Soper SA, Limbach PA. Interfacing a polymer-based micromachined device to a nanoelectrospray ionization fourier transform ion cyclotron resonance mass spectrometer Analytical Chemistry. 73: 1286-1291. PMID 11305664 DOI: 10.1021/ac000984a  1
2001 Ford SM, McCandless A, Liu X, Soper SA. Rapid fabrication of embossing tools for the production of polymeric microfluidic devices for bioanalytical applications Proceedings of Spie - the International Society For Optical Engineering. 4560: 207-216. DOI: 10.1117/12.443060  1
2000 Waddell E, Wang Y, Stryjewski W, McWhorter S, Henry AC, Evans D, McCarley RL, Soper SA. High-resolution near-infrared imaging of DNA microarrays with time-resolved acquisition of fluorescence lifetimes Analytical Chemistry. 72: 5907-5917. PMID 11140756 DOI: 10.1021/ac0009705  1
2000 Lassiter SJ, Stryjewski W, Legendre BL, Erdmann R, Wahl M, Wurm J, Peterson R, Middendorf L, Soper SA. Time-resolved fluorescence imaging of slab gels for lifetime base-calling in DNA sequencing applications. Analytical Chemistry. 72: 5373-82. PMID 11080890 DOI: 10.1021/ac000744v  1
2000 Henry AC, Tutt TJ, Galloway M, Davidson YY, McWhorter CS, Soper SA, McCarley RL. Surface modification of poly(methyl methacrylate) used in the fabrication of microanalytical devices Analytical Chemistry. 72: 5331-5337. PMID 11080884 DOI: 10.1021/ac000685l  1
2000 McWhorter S, Soper SA. Conductivity detection of polymerase chain reaction products separated by micro-reversed-phase liquid chromatography Journal of Chromatography A. 883: 1-9. PMID 10910196 DOI: 10.1016/S0021-9673(00)00327-7  1
2000 McWhorter S, Soper SA. Near-infrared laser-induced fluorescence detection in capillary electrophoresis Electrophoresis. 21: 1267-1280. PMID 10826670 DOI: 10.1002/(SICI)1522-2683(20000401)21:7<1267::AID-ELPS1267>3.0.CO;2-C  1
1999 Soper SA, Ford SM, Xu Y, Qi S, McWhorter S, Lassiter S, Patterson D, Bruch RC. Nanoliter-scale sample preparation methods directly coupled to polymethylmethacrylate-based microchips and gel-filled capillaries for the analysis of oligonucleotides. Journal of Chromatography. A. 853: 107-20. PMID 10486717 DOI: 10.1016/S0021-9673(99)00651-2  1
1999 Ford SM, Davies J, Kar B, Qi SD, McWhorter S, Soper SA, Malek CK. Micromachining in plastics using X-ray lithography for the fabrication of microelectrophoresis devices Journal of Biomechanical Engineering. 121: 13-21. PMID 10080084 DOI: 10.1115/1.2798035  1
1998 Soper SA, Williams DC, Xu Y, Lassiter SJ, Zhang Y, Ford SM, Bruch RC. Sanger DNA-sequencing reactions performed in a solid-phase nanoreactor directly coupled to capillary gel electrophoresis. Analytical Chemistry. 70: 4036-43. PMID 9784746 DOI: 10.1021/ac980288z  1
1998 Flanagan JH, Owens CV, Romero SE, Waddell E, Kahn SH, Hammer RP, Soper SA. Near-infrared heavy-atom-modified fluorescent dyes for base-calling in DNA-sequencing applications using temporal discrimination. Analytical Chemistry. 70: 2676-84. PMID 9666731  1
1998 Kar S, McWhorter S, Ford SM, Soper SA. Piezoelectric mechanical pump with nanoliter per minute pulse-free flow delivery for pressure pumping in micro-channels Analyst. 123: 1435-1441. DOI: 10.1039/a800052b  1
1997 Legendre BL, Moberg DL, Williams DC, Soper SA. Ultrasensitive near-infrared laser-induced fluorescence detection in capillary electrophoresis using a diode laser and avalanche photodiode Journal of Chromatography A. 779: 185-194. PMID 9335121 DOI: 10.1016/S0021-9673(97)00405-6  1
1997 Flanagan JH, Khan SH, Menchen S, Soper SA, Hammer RP. Functionalized tricarbocyanine dyes as near-infrared fluorescent probes for biomolecules. Bioconjugate Chemistry. 8: 751-6. PMID 9327141 DOI: 10.1021/bc970113g  1
1997 Flanagan JH, Romero SE, Legendre BL, Hammer RP, Soper SA. Heavy-atom modified near-IR fluorescent dyes for DNA sequencing applications: Synthesis and photophysical characterization Proceedings of Spie - the International Society For Optical Engineering. 2980: 328-337. DOI: 10.1117/12.273529  1
1996 Soper SA, Flanagan JH, Legendre BL, Williams DC, Hammer RP. Near-infrared, laser-induced fluorescence detection for DNA sequencing applications Ieee Journal On Selected Topics in Quantum Electronics. 2: 1129-1139. DOI: 10.1109/2944.577345  1
1996 Soper SA. Chapter 4 Optical detection strategies in capillary electrophoresis Progress in Pharmaceutical and Biomedical Analysis. 2: 181-228. DOI: 10.1016/S1464-3456(96)80021-4  1
1995 Williams DC, Soper SA. Ultrasensitive near-IR fluorescence detection for capillary gel electrophoresis and DNA sequencing applications Analytical Chemistry. 67: 3427-3432. PMID 8686892 DOI: 10.1021/ac00115a010  1
1995 Soper SA, Legendre BL, Williams DC. On-Line Fluorescence Lifetime Determinations in Capillary Electrophoresis Analytical Chemistry. 67: 4358-4365. PMID 8651478 DOI: 10.1021/ac00119a025  1
1995 Soper SA, Legendre BL, Huang J. Evaluation of thermodynamic and photophysical properties of tricarbocyanine near-IR dyes in organized media using single-molecule monitoring Chemical Physics Letters. 237: 339-345. DOI: 10.1016/0009-2614(95)00314-T  1
1992 Soper SA, Davis LM, Shera EB. Detection and identification of single molecules in solution Journal of the Optical Society of America B: Optical Physics. 9: 1761-1769. DOI: 10.1364/JOSAB.9.001761  0.6
1990 Brooks Shera E, Seitzinger NK, Davis LM, Keller RA, Soper SA. Detection of single fluorescent molecules Chemical Physics Letters. 174: 553-557. DOI: 10.1016/0009-2614(90)85485-U  1
1990 Soper SA, Chamberlin S, Johnson CK, Kuwana T. Intramolecular loss of fluorescence by lysine derivatized with naphthalenedialdehyde Applied Spectroscopy. 44: 858-863.  1
1990 Soper SA, Ratzlaff KL, Kuwana T. Surface-enhanced resonance raman spectroscopy of liquid chromatographic analytes on thin-layer chromatographic plates Analytical Chemistry. 62: 1438-1444.  1
1989 Soper SA, Kuwana T. Matrix-isolated Surface-Enhanced Raman Spectroscopy (SERS). The role of the supporting matrix Applied Spectroscopy. 43: 1180-1187.  1
1989 Soper SA, Kuwana T. Matrix-isolated luminescence of primary amines derivatized with naphthalenedialdehyde Applied Spectroscopy. 43: 883-886.  1
1988 Gui Y, Soper SA, Kuwana T. Thin-layer spectroelectrochemical cuvette cells with long optical path lengths Analytical Chemistry. 60: 1645-1648.  1
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