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David R. Davies, Ph.D. - Publications

Affiliations: 
NIDDK, NIH, Bethesda, MD, United States 
Area:
structural biology, crystallography, innate immune system
Website:
http://www-mslmb.niddk.nih.gov/davies/david.html

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 Botos I, Segal DM, Davies DR. The structural biology of Toll-like receptors. Structure (London, England : 1993). 19: 447-59. PMID 21481769 DOI: 10.1016/J.Str.2011.02.004  1
2010 Wang Y, Liu L, Davies DR, Segal DM. Dimerization of Toll-like receptor 3 (TLR3) is required for ligand binding. The Journal of Biological Chemistry. 285: 36836-41. PMID 20861016 DOI: 10.1074/Jbc.M110.167973  1
2010 Gleick PH, Adams RM, Amasino RM, Anders E, Anderson DJ, Anderson WW, Anselin LE, Arroyo MK, Asfaw B, Ayala FJ, Bax A, Bebbington AJ, Bell G, Bennett MV, Bennetzen JL, ... ... Davies DR, et al. Climate change and the integrity of science. Science (New York, N.Y.). 328: 689-90. PMID 20448167 DOI: 10.1126/Science.328.5979.689  0.52
2010 Li M, Chen C, Davies DR, Chiu TK. Induced-fit mechanism for prolyl endopeptidase. The Journal of Biological Chemistry. 285: 21487-95. PMID 20444688 DOI: 10.1074/Jbc.M109.092692  1
2010 Botos I, Davies DR. Toll-like receptors-structureand signaling Handbook of Cell Signaling, 2/E. 1: 139-143. DOI: 10.1016/B978-0-12-374145-5.00021-8  1
2009 Botos I, Liu L, Wang Y, Segal DM, Davies DR. The toll-like receptor 3:dsRNA signaling complex. Biochimica Et Biophysica Acta. 1789: 667-74. PMID 19595807 DOI: 10.1016/J.Bbagrm.2009.06.005  1
2008 Liu L, Botos I, Wang Y, Leonard JN, Shiloach J, Segal DM, Davies DR. Structural basis of toll-like receptor 3 signaling with double-stranded RNA. Science (New York, N.Y.). 320: 379-81. PMID 18420935 DOI: 10.1126/Science.1155406  1
2008 Leonard JN, Ghirlando R, Askins J, Bell JK, Margulies DH, Davies DR, Segal DM. The TLR3 signaling complex forms by cooperative receptor dimerization. Proceedings of the National Academy of Sciences of the United States of America. 105: 258-63. PMID 18172197 DOI: 10.1073/Pnas.0710779105  1
2006 Bell JK, Botos I, Hall PR, Askins J, Shiloach J, Davies DR, Segal DM. The molecular structure of the TLR3 extracellular domain. Journal of Endotoxin Research. 12: 375-8. PMID 17254392 DOI: 10.1179/096805106X118780  0.36
2006 Bell JK, Askins J, Hall PR, Davies DR, Segal DM. The dsRNA binding site of human Toll-like receptor 3. Proceedings of the National Academy of Sciences of the United States of America. 103: 8792-7. PMID 16720699 DOI: 10.1073/Pnas.0603245103  0.36
2006 Kubelka J, Chiu TK, Davies DR, Eaton WA, Hofrichter J. Sub-microsecond protein folding. Journal of Molecular Biology. 359: 546-53. PMID 16643946 DOI: 10.1016/J.Jmb.2006.03.034  1
2005 Bell JK, Botos I, Hall PR, Askins J, Shiloach J, Segal DM, Davies DR. The molecular structure of the Toll-like receptor 3 ligand-binding domain. Proceedings of the National Academy of Sciences of the United States of America. 102: 10976-80. PMID 16043704 DOI: 10.1073/Pnas.0505077102  0.36
2005 Chiu TK, Kubelka J, Herbst-Irmer R, Eaton WA, Hofrichter J, Davies DR. High-resolution x-ray crystal structures of the villin headpiece subdomain, an ultrafast folding protein. Proceedings of the National Academy of Sciences of the United States of America. 102: 7517-22. PMID 15894611 DOI: 10.1073/Pnas.0502495102  1
2005 Baxa U, Cheng N, Winkler DC, Chiu TK, Davies DR, Sharma D, Inouye H, Kirschner DA, Wickner RB, Steven AC. Filaments of the Ure2p prion protein have a cross-beta core structure. Journal of Structural Biology. 150: 170-9. PMID 15866740 DOI: 10.1016/J.Jsb.2005.02.007  1
2005 Cohen GH, Silverton EW, Padlan EA, Dyda F, Wibbenmeyer JA, Willson RC, Davies DR. Water molecules in the antibody-antigen interface of the structure of the Fab HyHEL-5-lysozyme complex at 1.7 A resolution: comparison with results from isothermal titration calorimetry. Acta Crystallographica. Section D, Biological Crystallography. 61: 628-33. PMID 15858274 DOI: 10.1107/S0907444905007870  1
2004 Chiu TK, Davies DR. Structure and function of HIV-1 integrase. Current Topics in Medicinal Chemistry. 4: 965-77. PMID 15134551 DOI: 10.2174/1568026043388547  1
2003 Bell JK, Mullen GE, Leifer CA, Mazzoni A, Davies DR, Segal DM. Leucine-rich repeats and pathogen recognition in Toll-like receptors. Trends in Immunology. 24: 528-33. PMID 14552836 DOI: 10.1016/S1471-4906(03)00242-4  0.36
2003 Mullen GE, Kennedy MN, Visintin A, Mazzoni A, Leifer CA, Davies DR, Segal DM. The role of disulfide bonds in the assembly and function of MD-2. Proceedings of the National Academy of Sciences of the United States of America. 100: 3919-24. PMID 12642668 DOI: 10.1073/Pnas.0630495100  0.36
2001 Umland TC, Taylor KL, Rhee S, Wickner RB, Davies DR. The crystal structure of the nitrogen regulation fragment of the yeast prion protein Ure2p. Proceedings of the National Academy of Sciences of the United States of America. 98: 1459-64. PMID 11171973 DOI: 10.1073/Pnas.98.4.1459  1
1999 Goldgur Y, Craigie R, Cohen GH, Fujiwara T, Yoshinaga T, Fujishita T, Sugimoto H, Endo T, Murai H, Davies DR. Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: A platform for antiviral drug design Proceedings of the National Academy of Sciences of the United States of America. 96: 13040-13043. PMID 10557269 DOI: 10.1073/Pnas.96.23.13040  1
1998 Goldgur Y, Dyda F, Hickman AB, Jenkins TM, Craigie R, Davies DR. Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium. Proceedings of the National Academy of Sciences of the United States of America. 95: 9150-4. PMID 9689049 DOI: 10.1073/Pnas.95.16.9150  1
1996 Cohen GH, Sheriff S, Davies DR. Refined structure of the monoclonal antibody HyHEL-5 with its antigen hen egg-white lysozyme. Acta Crystallographica. Section D, Biological Crystallography. 52: 315-26. PMID 15299704 DOI: 10.1107/S0907444995014855  0.52
1996 Chacko S, Silverton EW, Smith-Gill SJ, Davies DR, Shick KA, Xavier KA, Willson RC, Jeffrey PD, Chang CY, Sieker LC, Sheriff S. Refined structures of bobwhite quail lysozyme uncomplexed and complexed with the HyHEL-5 Fab fragment. Proteins. 26: 55-65. PMID 8880929 DOI: 10.1002/(Sici)1097-0134(199609)26:1<55::Aid-Prot5>3.0.Co;2-F  1
1996 Rice P, Craigie R, Davies DR. Retroviral integrases and their cousins Current Opinion in Structural Biology. 6: 76-83. PMID 8696976 DOI: 10.1016/S0959-440X(96)80098-4  1
1996 Davies DR, Cohen GH. Interactions of protein antigens with antibodies Proceedings of the National Academy of Sciences of the United States of America. 93: 7-12. PMID 8552677 DOI: 10.1073/Pnas.93.1.7  1
1995 Jenkins TM, Hickman AB, Dyda F, Ghirlando R, Davies DR, Craigie R. Catalytic domain of human immunodeficiency virus type 1 integrase: Identification of a soluble mutant by systematic replacement of hydrophobic residues Proceedings of the National Academy of Sciences of the United States of America. 92: 6057-6061. PMID 7597080 DOI: 10.1073/Pnas.92.13.6057  1
1994 Dyda F, Hickman AB, Jenkins TM, Engelman A, Craigie R, Davies DR. Crystal structure of the catalytic domain of HIV-1 integrase: Similarity to other polynucleotidyl transferases Science. 266: 1981-1986. PMID 7801124 DOI: 10.1126/Science.7801124  1
1992 Parris KD, Hoover DJ, Damon DB, Davies DR. Synthesis and crystallographic analysis of two rhizopuspepsin inhibitor complexes. Biochemistry. 31: 8125-41. PMID 1525154 DOI: 10.1021/Bi00150A004  1
1992 Shaanan B, Gronenborn AM, Cohen GH, Gilliland GL, Veerapandian B, Davies DR, Clore GM. Combining experimental information from crystal and solution studies: Joint X-ray and NMR refinement Science. 257: 961-964. PMID 1502561 DOI: 10.1126/Science.1502561  1
1991 Wilmanns M, Hyde CC, Davies DR, Kirschner K, Jansonius JN. Structural conservation in parallel beta/alpha-barrel enzymes that catalyze three sequential reactions in the pathway of tryptophan biosynthesis. Biochemistry. 30: 9161-9. PMID 1892826 DOI: 10.1021/Bi00102A006  1
1991 Parris KD, Hoover DJ, Davies DR. Crystal structures of rhizopuspepsin/inhibitor complexes Advances in Experimental Medicine and Biology. 306: 217-231. PMID 1812709 DOI: 10.1007/978-1-4684-6012-4_26  1
1991 Rich A, Davies DR, Felsenfeld G. Triplex RNA. Science (New York, N.Y.). 253: 17. PMID 1712122 DOI: 10.1126/science.1712122  1
1989 Padlan EA, Silverton EW, Sheriff S, Cohen GH, Smith-Gill SJ, Davies DR. Structure of an antibody-antigen complex: Crystal structure of the HyHEL-10 Fab-lysozyme complex Proceedings of the National Academy of Sciences of the United States of America. 86: 5938-5942. PMID 2762305 DOI: 10.1073/Pnas.86.15.5938  1
1989 Chothia C, Lesk AM, Tramontano A, Levitt M, Smith-Gill SJ, Air G, Sheriff S, Padlan EA, Davies D, Tulip WR. Conformations of immunoglobulin hypervariable regions. Nature. 342: 877-83. PMID 2687698 DOI: 10.1038/342877A0  1
1987 Sheriff S, Silverton EW, Padlan EA, Cohen GH, Smith-Gill SJ, Finzel BC, Davies DR. Three-dimensional structure of an antibody-antigen complex. Proceedings of the National Academy of Sciences of the United States of America. 84: 8075-9. PMID 2446316 DOI: 10.1073/Pnas.84.22.8075  1
1986 Padlan EA, Cohen GH, Davies DR. Antibody Fab assembly: The interface residues between CH1 and CL Molecular Immunology. 23: 951-960. PMID 3097521 DOI: 10.1016/0161-5890(86)90125-2  0.52
1985 Padlan EA, Cohen GH, Davies DR. On the specificity of antibody/antigen interactions: phosphocholine binding to McPC603 and the correlation of three-dimensional structure and sequence data. Annales De L'Institut Pasteur. Immunologie. 136: 271-276. PMID 3890687 DOI: 10.1016/S0769-2625(85)80058-1  0.52
1985 Satow Y, Cohen GH, Padlan EA, Davies DR. Phosphocholine binding immunoglobulin Fab McPC603. An X-ray diffraction study at 2.7 A. Journal of Molecular Biology. 190: 593-604. PMID 3097327 DOI: 10.1016/0022-2836(86)90245-7  0.52
1982 Bott R, Subramanian E, Davies DR. Three-dimensional structure of the complex of the Rhizopus chinensis carboxyl proteinase and pepstatin at 2.5-Å resolution Biochemistry. 21: 6956-6962. PMID 6760895 DOI: 10.1021/Bi00269A052  1
1977 Silverton EW, Navia MA, Davies DR. Three-dimensional structure of an intact human immunoglobulin. Proceedings of the National Academy of Sciences of the United States of America. 74: 5140-5144. PMID 270751 DOI: 10.1073/Pnas.74.11.5140  0.44
1976 Richardson JS, Richardson DC, Thomas KA, Silverton EW, Davies DR. Similarity of three-dimensional structure between the immunoglobulin domain and the copper, zinc superoxide dismutase subunit. Journal of Molecular Biology. 102: 221-35. PMID 1271464 DOI: 10.1016/S0022-2836(76)80050-2  1
1975 Kabat EA, Padlan EA, Davies DR. Evolutionary and structural influences on light chain constant (C(L)) region of human and mouse immunoglobulins Proceedings of the National Academy of Sciences of the United States of America. 72: 2785-2788. PMID 809770 DOI: 10.1073/pnas.72.7.2785  1
1972 Segal DM, Cohen CH, Davies DR, Powers JC, Wilcox PE. The stereochemistry of substrate binding to chymotrypsin A . Cold Spring Harbor Symposia On Quantitative Biology. 36: 85-90. PMID 4508176 DOI: 10.1101/SQB.1972.036.01.014  1
1972 Sarma VR, Davies DR, Labaw LW, Silverton EW, Terry WD. Crystal structure of an immunoglobulin molecule by x-ray diffraction and electron microscopy. Cold Spring Harbor Symposia On Quantitative Biology. 36: 413-9. PMID 4508154 DOI: 10.1101/Sqb.1972.036.01.053  0.48
1971 Segal DM, Powers JC, Cohen GH, Davies DR, Wilcox PE. Substrate binding site in bovine chymotrypsin A-gamma. A crystallographic study using peptide chloromethyl ketones as site-specific inhibitors. Biochemistry. 10: 3728-38. PMID 5107010 DOI: 10.1021/bi00796a014  1
1970 Cohen GH, Matthews BW, Davies DR. The relation between gamma-and alpha-chymotrypsin. II. Direct comparison of the electron densities at 5-5 Angstrom resolution. Acta Crystallographica. Section B: Structural Crystallography and Crystal Chemistry. 26: 1062-9. PMID 5537151  0.52
1969 Cohen GH, Silverton EW, Matthews BW, Braxton H, Davies DR. Structure of gamma-chymotrypsin at 5.5 A resolution. Journal of Molecular Biology. 44: 129-41. PMID 5822897 DOI: 10.1016/0022-2836(69)90409-4  1
1968 Matthews BW, Cohen GH, Silverton EW, Braxton H, Davies DR. Relation between gamma- and alpha-chymotrypsin. Journal of Molecular Biology. 36: 179-83. PMID 5760536 DOI: 10.1016/0022-2836(68)90228-3  1
1968 Terry WD, Matthews BW, Davies DR. Crystallographic studies of a human immunoglobulin. Nature. 220: 239-41. PMID 4176457 DOI: 10.1038/220239A0  0.52
1964 SIGLER PB, SKINNER HC, COULTER CL, KALLOS J, BRAXTON H, DAVIES DR. AN ISOMORPHOUS HEAVY ATOM SUBSTITUTION AT THE ACTIVE SITE OF Proceedings of the National Academy of Sciences of the United States Of. 51: 1146-1151. PMID 14215636 DOI: 10.1073/Pnas.51.6.1146  1
1962 SIGLER PB, DAVIES DR, MILES HT. A displacement reaction between a polynucleotide Helix and a random coil Journal of Molecular Biology. 5: 709-717. PMID 13989046 DOI: 10.1016/S0022-2836(62)80097-7  1
1961 RICH A, DAVIES DR, CRICK FH, WATSON JD. The molecular structure of polyadenylic acid. Journal of Molecular Biology. 3: 71-86. PMID 13741242 DOI: 10.1016/S0022-2836(61)80009-0  1
1956 Rich A, Davies DR. A NEW TWO STRANDED HELICAL STRUCTURE: POLYADENYLIC ACID AND POLYURIDYLIC ACID Journal of the American Chemical Society. 78: 3548-3549. DOI: 10.1021/Ja01595A086  0.36
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