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Kevin M. Weeks - Publications

Chemistry University of North Carolina, Chapel Hill, Chapel Hill, NC 
Structural and Chemical Biology of the Transcriptome

115 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Warner KD, Hajdin CE, Weeks KM. Principles for targeting RNA with drug-like small molecules. Nature Reviews. Drug Discovery. PMID 29977051 DOI: 10.1038/Nrd.2018.93  0.44
2018 Mustoe AM, Busan S, Rice GM, Hajdin CE, Peterson BK, Ruda VM, Kubica N, Nutiu R, Baryza JL, Weeks KM. Pervasive Regulatory Functions of mRNA Structure Revealed by High-Resolution SHAPE Probing. Cell. PMID 29551268 DOI: 10.1016/J.Cell.2018.02.034  0.44
2015 Smola MJ, Calabrese JM, Weeks KM. Detection of RNA-Protein Interactions in Living Cells with SHAPE. Biochemistry. PMID 26544910 DOI: 10.1021/Acs.Biochem.5B00977  1
2015 Lu YF, Mauger DM, Goldstein DB, Urban TJ, Weeks KM, Bradrick SS. IFNL3 mRNA structure is remodeled by a functional non-coding polymorphism associated with hepatitis C virus clearance. Scientific Reports. 5: 16037. PMID 26531896 DOI: 10.1038/Srep16037  1
2015 Tyrrell J, Weeks KM, Pielak GJ. Challenge of Mimicking the Influences of the Cellular Environment on RNA Structure by PEG-Induced Macromolecular Crowding. Biochemistry. 54: 6447-53. PMID 26430778 DOI: 10.1021/Acs.Biochem.5B00767  1
2015 Smola MJ, Rice GM, Busan S, Siegfried NA, Weeks KM. Selective 2'-hydroxyl acylation analyzed by primer extension and mutational profiling (SHAPE-MaP) for direct, versatile and accurate RNA structure analysis. Nature Protocols. 10: 1643-69. PMID 26426499 DOI: 10.1038/Nprot.2015.103  1
2015 Kutchko KM, Sanders W, Ziehr B, Phillips G, Solem A, Halvorsen M, Weeks KM, Moorman N, Laederach A. Multiple conformations are a conserved and regulatory feature of the RB1 5' UTR. Rna (New York, N.Y.). 21: 1274-85. PMID 25999316 DOI: 10.1261/Rna.049221.114  1
2015 Lavender CA, Gorelick RJ, Weeks KM. Structure-Based Alignment and Consensus Secondary Structures for Three HIV-Related RNA Genomes. Plos Computational Biology. 11: e1004230. PMID 25992893 DOI: 10.1371/Journal.Pcbi.1004230  1
2015 Lavender CA, Lorenz R, Zhang G, Tamayo R, Hofacker IL, Weeks KM. Model-Free RNA Sequence and Structure Alignment Informed by SHAPE Probing Reveals a Conserved Alternate Secondary Structure for 16S rRNA. Plos Computational Biology. 11: e1004126. PMID 25992778 DOI: 10.1371/Journal.Pcbi.1004126  1
2015 Weeks KM. RNA clubs. Rna (New York, N.Y.). 21: 760-1. PMID 25780225 DOI: 10.1261/rna.050476.115  1
2015 Mauger DM, Golden M, Yamane D, Williford S, Lemon SM, Martin DP, Weeks KM. Functionally conserved architecture of hepatitis C virus RNA genomes. Proceedings of the National Academy of Sciences of the United States of America. 112: 3692-7. PMID 25775547 DOI: 10.1073/Pnas.1416266112  1
2015 McGinnis JL, Liu Q, Lavender CA, Devaraj A, McClory SP, Fredrick K, Weeks KM. In-cell SHAPE reveals that free 30S ribosome subunits are in the inactive state. Proceedings of the National Academy of Sciences of the United States of America. 112: 2425-30. PMID 25675474 DOI: 10.1073/Pnas.1411514112  1
2015 Weeks KM. Review toward all RNA structures, concisely. Biopolymers. 103: 438-48. PMID 25546503 DOI: 10.1002/Bip.22601  1
2015 Taylor AI, Pinheiro VB, Smola MJ, Morgunov AS, Peak-Chew S, Cozens C, Weeks KM, Herdewijn P, Holliger P. Catalysts from synthetic genetic polymers. Nature. 518: 427-30. PMID 25470036 DOI: 10.1038/Nature13982  1
2014 Rice GM, Busan S, Karabiber F, Favorov OV, Weeks KM. SHAPE analysis of small RNAs and riboswitches. Methods in Enzymology. 549: 165-87. PMID 25432749 DOI: 10.1016/B978-0-12-801122-5.00008-8  1
2014 Homan PJ, Tandon A, Rice GM, Ding F, Dokholyan NV, Weeks KM. RNA tertiary structure analysis by 2'-hydroxyl molecular interference. Biochemistry. 53: 6825-33. PMID 25341083 DOI: 10.1021/Bi501218G  1
2014 Homan PJ, Favorov OV, Lavender CA, Kursun O, Ge X, Busan S, Dokholyan NV, Weeks KM. Single-molecule correlated chemical probing of RNA. Proceedings of the National Academy of Sciences of the United States of America. 111: 13858-63. PMID 25205807 DOI: 10.1073/Pnas.1407306111  1
2014 Siegfried NA, Busan S, Rice GM, Nelson JA, Weeks KM. RNA motif discovery by SHAPE and mutational profiling (SHAPE-MaP). Nature Methods. 11: 959-65. PMID 25028896 DOI: 10.1038/Nmeth.3029  1
2014 Low JT, Garcia-Miranda P, Mouzakis KD, Gorelick RJ, Butcher SE, Weeks KM. Structure and dynamics of the HIV-1 frameshift element RNA. Biochemistry. 53: 4282-91. PMID 24926888 DOI: 10.1021/Bi5004926  1
2014 McGinnis JL, Weeks KM. Ribosome RNA assembly intermediates visualized in living cells. Biochemistry. 53: 3237-47. PMID 24818530 DOI: 10.1021/Bi500198B  1
2014 Warner KD, Homan P, Weeks KM, Smith AG, Abell C, Ferré-D'Amaré AR. Validating fragment-based drug discovery for biological RNAs: lead fragments bind and remodel the TPP riboswitch specifically. Chemistry & Biology. 21: 591-5. PMID 24768306 DOI: 10.1016/J.Chembiol.2014.03.007  1
2014 Rice GM, Leonard CW, Weeks KM. RNA secondary structure modeling at consistent high accuracy using differential SHAPE. Rna (New York, N.Y.). 20: 846-54. PMID 24742934 DOI: 10.1261/Rna.043323.113  1
2014 Grohman JK, Gorelick RJ, Kottegoda S, Allbritton NL, Rein A, Weeks KM. An immature retroviral RNA genome resembles a kinetically trapped intermediate state. Journal of Virology. 88: 6061-8. PMID 24623442 DOI: 10.1128/Jvi.03277-13  1
2013 Tyrrell J, McGinnis JL, Weeks KM, Pielak GJ. The cellular environment stabilizes adenine riboswitch RNA structure. Biochemistry. 52: 8777-85. PMID 24215455 DOI: 10.1021/Bi401207Q  1
2013 Busan S, Weeks KM. Role of context in RNA structure: flanking sequences reconfigure CAG motif folding in huntingtin exon 1 transcripts. Biochemistry. 52: 8219-25. PMID 24199621 DOI: 10.1021/Bi401129R  1
2013 Archer EJ, Simpson MA, Watts NJ, O'Kane R, Wang B, Erie DA, McPherson A, Weeks KM. Long-range architecture in a viral RNA genome. Biochemistry. 52: 3182-90. PMID 23614526 DOI: 10.1021/Bi4001535  1
2013 Pollom E, Dang KK, Potter EL, Gorelick RJ, Burch CL, Weeks KM, Swanstrom R. Comparison of SIV and HIV-1 genomic RNA structures reveals impact of sequence evolution on conserved and non-conserved structural motifs. Plos Pathogens. 9: e1003294. PMID 23593004 DOI: 10.1371/Journal.Ppat.1003294  1
2013 Hajdin CE, Bellaousov S, Huggins W, Leonard CW, Mathews DH, Weeks KM. Accurate SHAPE-directed RNA secondary structure modeling, including pseudoknots. Proceedings of the National Academy of Sciences of the United States of America. 110: 5498-503. PMID 23503844 DOI: 10.1073/Pnas.1219988110  1
2013 Mauger DM, Siegfried NA, Weeks KM. The genetic code as expressed through relationships between mRNA structure and protein function. Febs Letters. 587: 1180-8. PMID 23499436 DOI: 10.1016/J.Febslet.2013.03.002  1
2013 Grohman JK, Gorelick RJ, Lickwar CR, Lieb JD, Bower BD, Znosko BM, Weeks KM. A guanosine-centric mechanism for RNA chaperone function. Science (New York, N.Y.). 340: 190-5. PMID 23470731 DOI: 10.1126/Science.1230715  1
2013 Leonard CW, Hajdin CE, Karabiber F, Mathews DH, Favorov OV, Dokholyan NV, Weeks KM. Principles for understanding the accuracy of SHAPE-directed RNA structure modeling. Biochemistry. 52: 588-95. PMID 23316814 DOI: 10.1021/Bi300755U  1
2013 Ramachandran S, Ding F, Weeks KM, Dokholyan NV. Statistical analysis of SHAPE-directed RNA secondary structure modeling. Biochemistry. 52: 596-9. PMID 23286327 DOI: 10.1021/Bi300756S  1
2013 Karabiber F, McGinnis JL, Favorov OV, Weeks KM. QuShape: rapid, accurate, and best-practices quantification of nucleic acid probing information, resolved by capillary electrophoresis. Rna (New York, N.Y.). 19: 63-73. PMID 23188808 DOI: 10.1261/Rna.036327.112  1
2012 Steen KA, Rice GM, Weeks KM. Fingerprinting noncanonical and tertiary RNA structures by differential SHAPE reactivity. Journal of the American Chemical Society. 134: 13160-3. PMID 22852530 DOI: 10.1021/Ja304027M  1
2012 Ding F, Lavender CA, Weeks KM, Dokholyan NV. Three-dimensional RNA structure refinement by hydroxyl radical probing. Nature Methods. 9: 603-8. PMID 22504587 DOI: 10.1038/Nmeth.1976  1
2012 McGinnis JL, Dunkle JA, Cate JH, Weeks KM. The mechanisms of RNA SHAPE chemistry. Journal of the American Chemical Society. 134: 6617-24. PMID 22475022 DOI: 10.1021/Ja2104075  1
2012 Cruz JA, Blanchet MF, Boniecki M, Bujnicki JM, Chen SJ, Cao S, Das R, Ding F, Dokholyan NV, Flores SC, Huang L, Lavender CA, Lisi V, Major F, Mikolajczak K, ... ... Weeks KM, et al. RNA-Puzzles: a CASP-like evaluation of RNA three-dimensional structure prediction. Rna (New York, N.Y.). 18: 610-25. PMID 22361291 DOI: 10.1261/Rna.031054.111  1
2012 Low JT, Knoepfel SA, Watts JM, ter Brake O, Berkhout B, Weeks KM. SHAPE-directed discovery of potent shRNA inhibitors of HIV-1. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 820-8. PMID 22314289 DOI: 10.1038/Mt.2011.299  1
2011 Grohman JK, Kottegoda S, Gorelick RJ, Allbritton NL, Weeks KM. Femtomole SHAPE reveals regulatory structures in the authentic XMRV RNA genome. Journal of the American Chemical Society. 133: 20326-34. PMID 22126209 DOI: 10.1021/Ja2070945  1
2011 Steen KA, Siegfried NA, Weeks KM. Selective 2'-hydroxyl acylation analyzed by protection from exoribonuclease (RNase-detected SHAPE) for direct analysis of covalent adducts and of nucleotide flexibility in RNA. Nature Protocols. 6: 1683-94. PMID 21979276 DOI: 10.1038/Nprot.2011.373  1
2011 Weeks KM. RNA structure probing dash seq. Proceedings of the National Academy of Sciences of the United States of America. 108: 10933-4. PMID 21700884 DOI: 10.1073/Pnas.1107835108  1
2011 Weeks KM, Mauger DM. Exploring RNA structural codes with SHAPE chemistry. Accounts of Chemical Research. 44: 1280-91. PMID 21615079 DOI: 10.1021/Ar200051H  1
2011 Rocca-Serra P, Bellaousov S, Birmingham A, Chen C, Cordero P, Das R, Davis-Neulander L, Duncan CD, Halvorsen M, Knight R, Leontis NB, Mathews DH, Ritz J, Stombaugh J, Weeks KM, et al. Sharing and archiving nucleic acid structure mapping data. Rna (New York, N.Y.). 17: 1204-12. PMID 21610212 DOI: 10.1261/Rna.2753211  1
2011 Karabiber F, Weeks K, Favorov OV. Automated peak alignment for nucleic acid capillary electrophoresis data by dynamic programming 2011 Acm Conference On Bioinformatics, Computational Biology and Biomedicine, Bcb 2011. 544-546. DOI: 10.1145/2147805.2147895  1
2010 Mauger DM, Weeks KM. Toward global RNA structure analysis. Nature Biotechnology. 28: 1178-9. PMID 21057487 DOI: 10.1038/Nbt1110-1178  1
2010 Gherghe C, Lombo T, Leonard CW, Datta SA, Bess JW, Gorelick RJ, Rein A, Weeks KM. Definition of a high-affinity Gag recognition structure mediating packaging of a retroviral RNA genome. Proceedings of the National Academy of Sciences of the United States of America. 107: 19248-53. PMID 20974908 DOI: 10.1073/Pnas.1006897107  1
2010 Simon-Loriere E, Martin DP, Weeks KM, Negroni M. RNA structures facilitate recombination-mediated gene swapping in HIV-1. Journal of Virology. 84: 12675-82. PMID 20881047 DOI: 10.1128/Jvi.01302-10  1
2010 Steen KA, Malhotra A, Weeks KM. Selective 2'-hydroxyl acylation analyzed by protection from exoribonuclease. Journal of the American Chemical Society. 132: 9940-3. PMID 20597503 DOI: 10.1021/Ja103781U  1
2010 Low JT, Weeks KM. SHAPE-directed RNA secondary structure prediction. Methods (San Diego, Calif.). 52: 150-8. PMID 20554050 DOI: 10.1016/J.Ymeth.2010.06.007  1
2010 Lavender CA, Ding F, Dokholyan NV, Weeks KM. Robust and generic RNA modeling using inferred constraints: a structure for the hepatitis C virus IRES pseudoknot domain. Biochemistry. 49: 4931-3. PMID 20545364 DOI: 10.1021/Bi100142Y  1
2010 Duncan CD, Weeks KM. Nonhierarchical ribonucleoprotein assembly suggests a strain-propagation model for protein-facilitated RNA folding. Biochemistry. 49: 5418-25. PMID 20533823 DOI: 10.1021/Bi100267G  1
2010 Hajdin CE, Ding F, Dokholyan NV, Weeks KM. On the significance of an RNA tertiary structure prediction. Rna (New York, N.Y.). 16: 1340-9. PMID 20498460 DOI: 10.1261/Rna.1837410  1
2010 Weeks KM. Advances in RNA structure analysis by chemical probing. Current Opinion in Structural Biology. 20: 295-304. PMID 20447823 DOI: 10.1016/J.Sbi.2010.04.001  1
2010 Duncan CD, Weeks KM. The Mrs1 splicing factor binds the bI3 group I intron at each of two tetraloop-receptor motifs. Plos One. 5: e8983. PMID 20126554 DOI: 10.1371/Journal.Pone.0008983  1
2010 Gherghe C, Leonard CW, Gorelick RJ, Weeks KM. Secondary structure of the mature ex virio Moloney murine leukemia virus genomic RNA dimerization domain. Journal of Virology. 84: 898-906. PMID 19889760 DOI: 10.1128/Jvi.01602-09  1
2009 McGinnis JL, Duncan CD, Weeks KM. High-throughput SHAPE and hydroxyl radical analysis of RNA structure and ribonucleoprotein assembly. Methods in Enzymology. 468: 67-89. PMID 20946765 DOI: 10.1016/S0076-6879(09)68004-6  1
2009 Mortimer SA, Weeks KM. Time-resolved RNA SHAPE chemistry: quantitative RNA structure analysis in one-second snapshots and at single-nucleotide resolution. Nature Protocols. 4: 1413-21. PMID 19745823 DOI: 10.1038/Nprot.2009.126  1
2009 Mortimer SA, Weeks KM. C2'-endo nucleotides as molecular timers suggested by the folding of an RNA domain. Proceedings of the National Academy of Sciences of the United States of America. 106: 15622-7. PMID 19717440 DOI: 10.1073/Pnas.0901319106  1
2009 Watts JM, Dang KK, Gorelick RJ, Leonard CW, Bess JW, Swanstrom R, Burch CL, Weeks KM. Architecture and secondary structure of an entire HIV-1 RNA genome. Nature. 460: 711-6. PMID 19661910 DOI: 10.1038/Nature08237  1
2009 Wilkinson KA, Vasa SM, Deigan KE, Mortimer SA, Giddings MC, Weeks KM. Influence of nucleotide identity on ribose 2'-hydroxyl reactivity in RNA. Rna (New York, N.Y.). 15: 1314-21. PMID 19458034 DOI: 10.1261/Rna.1536209  1
2009 Mortimer SA, Johnson JS, Weeks KM. Quantitative analysis of RNA solvent accessibility by N-silylation of guanosine. Biochemistry. 48: 2109-14. PMID 19226117 DOI: 10.1021/Bi801939G  1
2009 Gherghe CM, Leonard CW, Ding F, Dokholyan NV, Weeks KM. Native-like RNA tertiary structures using a sequence-encoded cleavage agent and refinement by discrete molecular dynamics. Journal of the American Chemical Society. 131: 2541-6. PMID 19193004 DOI: 10.1021/Ja805460E  1
2009 Deigan KE, Li TW, Mathews DH, Weeks KM. Accurate SHAPE-directed RNA structure determination. Proceedings of the National Academy of Sciences of the United States of America. 106: 97-102. PMID 19109441 DOI: 10.1073/Pnas.0806929106  1
2008 Mortimer SA, Weeks KM. Time-resolved RNA SHAPE chemistry. Journal of the American Chemical Society. 130: 16178-80. PMID 18998638 DOI: 10.1021/Ja8061216  1
2008 Vasa SM, Guex N, Wilkinson KA, Weeks KM, Giddings MC. ShapeFinder: a software system for high-throughput quantitative analysis of nucleic acid reactivity information resolved by capillary electrophoresis. Rna (New York, N.Y.). 14: 1979-90. PMID 18772246 DOI: 10.1261/Rna.1166808  1
2008 Gherghe CM, Shajani Z, Wilkinson KA, Varani G, Weeks KM. Strong correlation between SHAPE chemistry and the generalized NMR order parameter (S2) in RNA. Journal of the American Chemical Society. 130: 12244-5. PMID 18710236 DOI: 10.1021/Ja804541S  1
2008 Duncan CD, Weeks KM. SHAPE analysis of long-range interactions reveals extensive and thermodynamically preferred misfolding in a fragile group I intron RNA. Biochemistry. 47: 8504-13. PMID 18642882 DOI: 10.1021/Bi800207B  1
2008 Maity TS, Fried HM, Weeks KM. Anti-cooperative assembly of the SRP19 and SRP68/72 components of the signal recognition particle. The Biochemical Journal. 415: 429-37. PMID 18564060 DOI: 10.1042/Bj20080569  1
2008 Gherghe CM, Mortimer SA, Krahn JM, Thompson NL, Weeks KM. Slow conformational dynamics at C2'-endo nucleotides in RNA. Journal of the American Chemical Society. 130: 8884-5. PMID 18558680 DOI: 10.1021/Ja802691E  1
2008 Wilkinson KA, Gorelick RJ, Vasa SM, Guex N, Rein A, Mathews DH, Giddings MC, Weeks KM. High-throughput SHAPE analysis reveals structures in HIV-1 genomic RNA strongly conserved across distinct biological states. Plos Biology. 6: e96. PMID 18447581 DOI: 10.1371/Journal.Pbio.0060096  1
2008 Jones CN, Wilkinson KA, Hung KT, Weeks KM, Spremulli LL. Lack of secondary structure characterizes the 5' ends of mammalian mitochondrial mRNAs. Rna (New York, N.Y.). 14: 862-71. PMID 18367717 DOI: 10.1261/Rna.909208  1
2008 Wang B, Wilkinson KA, Weeks KM. Complex ligand-induced conformational changes in tRNA(Asp) revealed by single-nucleotide resolution SHAPE chemistry. Biochemistry. 47: 3454-61. PMID 18290632 DOI: 10.1021/Bi702372X  1
2007 Maity TS, Weeks KM. A threefold RNA-protein interface in the signal recognition particle gates native complex assembly. Journal of Molecular Biology. 369: 512-24. PMID 17434535 DOI: 10.1016/J.Jmb.2007.03.032  1
2007 Mortimer SA, Weeks KM. A fast-acting reagent for accurate analysis of RNA secondary and tertiary structure by SHAPE chemistry. Journal of the American Chemical Society. 129: 4144-5. PMID 17367143 DOI: 10.1021/Ja0704028  1
2006 Wilkinson KA, Merino EJ, Weeks KM. Selective 2'-hydroxyl acylation analyzed by primer extension (SHAPE): quantitative RNA structure analysis at single nucleotide resolution. Nature Protocols. 1: 1610-6. PMID 17406453 DOI: 10.1038/Nprot.2006.249  1
2006 Maity TS, Leonard CW, Rose MA, Fried HM, Weeks KM. Compartmentalization directs assembly of the signal recognition particle. Biochemistry. 45: 14955-64. PMID 17154533 DOI: 10.1021/Bi060890G  1
2006 Badorrek CS, Weeks KM. Architecture of a gamma retroviral genomic RNA dimer. Biochemistry. 45: 12664-72. PMID 17042483 DOI: 10.1021/Bi060521K  1
2006 Gherghe C, Weeks KM. The SL1-SL2 (stem-loop) domain is the primary determinant for stability of the gamma retroviral genomic RNA dimer. The Journal of Biological Chemistry. 281: 37952-61. PMID 16984912 DOI: 10.1074/Jbc.M607380200  1
2006 Badorrek CS, Gherghe CM, Weeks KM. Structure of an RNA switch that enforces stringent retroviral genomic RNA dimerization. Proceedings of the National Academy of Sciences of the United States of America. 103: 13640-5. PMID 16945907 DOI: 10.1073/Pnas.0606156103  1
2006 Bokinsky G, Nivón LG, Liu S, Chai G, Hong M, Weeks KM, Zhuang X. Two distinct binding modes of a protein cofactor with its target RNA. Journal of Molecular Biology. 361: 771-84. PMID 16872630 DOI: 10.1016/J.Jmb.2006.06.048  1
2006 Li TW, Weeks KM. Structure-independent and quantitative ligation of single-stranded DNA. Analytical Biochemistry. 349: 242-6. PMID 16325753 DOI: 10.1016/J.Ab.2005.11.002  1
2005 Badorrek CS, Weeks KM. RNA flexibility in the dimerization domain of a gamma retrovirus. Nature Chemical Biology. 1: 104-11. PMID 16408007 DOI: 10.1038/Nchembio712  1
2005 Gherghe CM, Krahn JM, Weeks KM. Crystal structures, reactivity and inferred acylation transition states for 2'-amine substituted RNA. Journal of the American Chemical Society. 127: 13622-8. PMID 16190727 DOI: 10.1021/Ja053647Y  1
2005 Merino EJ, Weeks KM. Facile conversion of aptamers into sensors using a 2'-ribose-linked fluorophore. Journal of the American Chemical Society. 127: 12766-7. PMID 16159247 DOI: 10.1021/Ja053189T  1
2005 Longo A, Leonard CW, Bassi GS, Berndt D, Krahn JM, Hall TM, Weeks KM. Evolution from DNA to RNA recognition by the bI3 LAGLIDADG maturase. Nature Structural & Molecular Biology. 12: 779-87. PMID 16116439 DOI: 10.1038/Nsmb976  1
2005 Wilkinson KA, Merino EJ, Weeks KM. RNA SHAPE chemistry reveals nonhierarchical interactions dominate equilibrium structural transitions in tRNA(Asp) transcripts. Journal of the American Chemical Society. 127: 4659-67. PMID 15796531 DOI: 10.1021/Ja0436749  1
2005 Merino EJ, Wilkinson KA, Coughlan JL, Weeks KM. RNA structure analysis at single nucleotide resolution by selective 2'-hydroxyl acylation and primer extension (SHAPE). Journal of the American Chemical Society. 127: 4223-31. PMID 15783204 DOI: 10.1021/Ja043822V  1
2004 Buchmueller KL, Weeks KM. Tris-borate is a poor counterion for RNA: a cautionary tale for RNA folding studies. Nucleic Acids Research. 32: e184. PMID 15601995 DOI: 10.1093/Nar/Gnh182  1
2004 Garcia I, Weeks KM. Structural basis for the self-chaperoning function of an RNA collapsed state. Biochemistry. 43: 15179-86. PMID 15568809 DOI: 10.1021/Bi048626F  1
2004 John DM, Merino EJ, Weeks KM. Mechanics of DNA flexibility visualized by selective 2'-amine acylation at nucleotide bulges. Journal of Molecular Biology. 337: 611-9. PMID 15019781 DOI: 10.1016/J.Jmb.2004.01.029  1
2003 Buchmueller KL, Weeks KM. Near native structure in an RNA collapsed state. Biochemistry. 42: 13869-78. PMID 14636054 DOI: 10.1021/Bi035476K  1
2003 Merino EJ, Weeks KM. Fluorogenic resolution of ligand binding by a nucleic acid aptamer. Journal of the American Chemical Society. 125: 12370-1. PMID 14531655 DOI: 10.1021/Ja035299A  1
2003 Buchmueller KL, Hill BT, Platz MS, Weeks KM. RNA-tethered phenyl azide photocrosslinking via a short-lived indiscriminant electrophile. Journal of the American Chemical Society. 125: 10850-61. PMID 12952464 DOI: 10.1021/Ja035743+  1
2003 Bassi GS, Weeks KM. Kinetic and thermodynamic framework for assembly of the six-component bI3 group I intron ribonucleoprotein catalyst. Biochemistry. 42: 9980-8. PMID 12924947 DOI: 10.1021/Bi0346906  1
2003 Garcia I, Weeks KM. Small structural costs for evolution from RNA to RNP-based catalysis. Journal of Molecular Biology. 331: 57-73. PMID 12875836 DOI: 10.1016/S0022-2836(03)00686-7  1
2003 Chamberlin SI, Weeks KM. Differential helix stabilities and sites pre-organized for tertiary interactions revealed by monitoring local nucleotide flexibility in the bI5 group I intron RNA. Biochemistry. 42: 901-9. PMID 12549908 DOI: 10.1021/Bi026817H  1
2002 Chamberlin SI, Merino EJ, Weeks KM. Catalysis of amide synthesis by RNA phosphodiester and hydroxyl groups. Proceedings of the National Academy of Sciences of the United States of America. 99: 14688-93. PMID 12403820 DOI: 10.1073/Pnas.212527799  1
2002 John DM, Weeks KM. Chemical interrogation of mismatches in DNA-DNA and DNA-RNA duplexes under nonstringent conditions by selective 2'-amine acylation. Biochemistry. 41: 6866-74. PMID 12022892 DOI: 10.1021/Bi025611D  1
2002 Bassi GS, de Oliveira DM, White MF, Weeks KM. Recruitment of intron-encoded and co-opted proteins in splicing of the bI3 group I intron RNA. Proceedings of the National Academy of Sciences of the United States of America. 99: 128-33. PMID 11773622 DOI: 10.1073/Pnas.012579299  1
2001 Webb AE, Rose MA, Westhof E, Weeks KM. Protein-dependent transition states for ribonucleoprotein assembly. Journal of Molecular Biology. 309: 1087-100. PMID 11399081 DOI: 10.1006/Jmbi.2001.4714  1
2001 Rose MA, Weeks KM. Visualizing induced fit in early assembly of the human signal recognition particle. Nature Structural Biology. 8: 515-20. PMID 11373619 DOI: 10.1038/88577  1
2001 Webb AE, Weeks KM. A collapsed state functions to self-chaperone RNA folding into a native ribonucleoprotein complex. Nature Structural Biology. 8: 135-40. PMID 11175902 DOI: 10.1038/84124  1
2000 John DM, Weeks KM. van't Hoff enthalpies without baselines. Protein Science : a Publication of the Protein Society. 9: 1416-9. PMID 10933511 DOI: 10.1110/Ps.9.7.1416  1
2000 John DM, Weeks KM. Tagging DNA mismatches by selective 2'-amine acylation. Chemistry & Biology. 7: 405-10. PMID 10873837 DOI: 10.1016/S1074-5521(00)00121-6  1
2000 Buchmueller KL, Webb AE, Richardson DA, Weeks KM. A collapsed non-native RNA folding state. Nature Structural Biology. 7: 362-6. PMID 10802730 DOI: 10.1038/75125  1
2000 Chamberlin SI, Weeks KM. Mapping local nucleotide flexibility by selective acylation of 2'-amine substituted RNA Journal of the American Chemical Society. 122: 216-224. DOI: 10.1021/Ja9914137  1
1997 Weeks KM. Protein-facilitated RNA folding. Current Opinion in Structural Biology. 7: 336-42. PMID 9204274 DOI: 10.1016/S0959-440X(97)80048-6  1
1996 Weeks KM, Cech TR. Assembly of a ribonucleoprotein catalyst by tertiary structure capture. Science (New York, N.Y.). 271: 345-8. PMID 8553068 DOI: 10.1126/Science.271.5247.345  1
1995 Weeks KM, Cech TR. Protein facilitation of group I intron splicing by assembly of the catalytic core and the 5' splice site domain. Cell. 82: 221-30. PMID 7628013 DOI: 10.1016/0092-8674(95)90309-7  1
1995 Weeks KM, Cech TR. Efficient protein-facilitated splicing of the yeast mitochondrial bI5 intron. Biochemistry. 34: 7728-38. PMID 7540041 DOI: 10.1021/Bi00023A020  1
1993 Weeks KM, Crothers DM. Major groove accessibility of RNA. Science (New York, N.Y.). 261: 1574-7. PMID 7690496 DOI: 10.1126/Science.7690496  1
1993 Weeks KM, Crothers DM. RNA targeting by the HIV-1 Tat protein Perspectives in Drug Discovery and Design. 1: 225-234. DOI: 10.1007/Bf02171664  1
1992 Weeks KM, Crothers DM. RNA binding assays for Tat-derived peptides: implications for specificity. Biochemistry. 31: 10281-7. PMID 1384694 DOI: 10.1021/Bi00157A015  1
1991 Weeks KM, Crothers DM. RNA recognition by Tat-derived peptides: interaction in the major groove? Cell. 66: 577-88. PMID 1907891 DOI: 10.1016/0092-8674(81)90020-9  1
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