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Julia Gavrilyuk - Publications

Affiliations: 
2002-2007 University of Toronto, Toronto, ON, Canada 
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20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Nicolaou KC, Shelke YG, Dherange BD, Kempema A, Lin B, Gu C, Sandoval J, Hammond M, Aujay M, Gavrilyuk J. Design, Synthesis, and Biological Investigation of Epothilone B Analogues Featuring Lactone, Lactam, and Carbocyclic Macrocycles, Epoxide, Aziridine, and 1,1-Difluorocyclopropane and Other Fluorine Residues. The Journal of Organic Chemistry. PMID 32065746 DOI: 10.1021/Acs.Joc.0C00123  0.311
2020 Nicolaou KC, Das D, Lu Y, Rout S, Pitsinos EN, Lyssikatos J, Schammel A, Sandoval J, Hammond M, Aujay M, Gavrilyuk J. Total Synthesis and Biological Evaluation of Tiancimycins A and B, Yangpumicin A, and Related Anthraquinone-Fused Enediyne Antitumor Antibiotics. Journal of the American Chemical Society. PMID 31976660 DOI: 10.1021/Jacs.9B12522  0.348
2018 Nicolaou KC, Pulukuri KK, Rigol S, Peitsinis Z, Yu R, Kishigami S, Cen N, Aujay M, Sandoval J, Zepeda N, Gavrilyuk J. Short Total Synthesis of Δ12-Prostaglandin J2 and Related Prostaglandins. Design, Synthesis and Biological Evaluation of Macrocyclic Δ12-Prostaglandin J2 Analogues. The Journal of Organic Chemistry. PMID 30557504 DOI: 10.1021/Acs.Joc.8B03057  0.35
2018 Nicolaou KC, Li R, Lu Z, Pitsinos EN, Alemany LB, Aujay M, Lee C, Sandoval J, Gavrilyuk J. Streamlined Total Synthesis of Shishijimicin A and Its Application to the Design, Synthesis, and Biological Evaluation of Analogues thereof and Practical Syntheses of PhthNSSMe and Related Sulfenylating Reagents. Journal of the American Chemical Society. PMID 30216054 DOI: 10.1021/Jacs.8B06955  0.392
2018 Nicolaou KC, Erande RD, Yin J, Vourloumis D, Aujay M, Sandoval J, Munneke S, Gavrilyuk J. Improved Total Synthesis of Tubulysins and Design, Synthesis, and Biological Evaluation of New Tubulysins with Highly Potent Cytotoxicities against Cancer Cells as Potential Payloads for Antibody-Drug Conjugates. Journal of the American Chemical Society. PMID 29381062 DOI: 10.1021/Jacs.7B12692  0.31
2017 Nicolaou KC, Chen P, Zhu S, Cai Q, Erande RD, Li R, Sun H, Pulukuri KK, Rigol S, Aujay M, Sandoval J, Gavrilyuk J. Streamlined Total Synthesis of Trioxacarcins and Its Application to the Design, Synthesis, and Biological Evaluation of Analogues Thereof. Discovery of Simpler Designed and Potent Trioxacarcin Analogues. Journal of the American Chemical Society. PMID 29052423 DOI: 10.1021/Jacs.7B08820  0.4
2017 Nicolaou KC, Rhoades D, Wang Y, Bai R, Hamel E, Aujay M, Sandoval J, Gavrilyuk J. 12,13-Aziridinyl Epothilones. Stereoselective Synthesis of Trisubstituted Olefinic Bonds from Methyl Ketones and Heteroaromatic Phosphonates and Design, Synthesis, and Biological Evaluation of Potent Antitumor Agents. Journal of the American Chemical Society. PMID 28513142 DOI: 10.1021/Jacs.7B02655  0.42
2016 Nicolaou KC, Pulukuri KK, Rigol S, Heretsch P, Yu R, Grove CI, Hale CR, ElMarrouni A, Fetz V, Brönstrup M, Aujay M, Sandoval J, Gavrilyuk J. Synthesis and Biological Investigation of Δ(12)-Prostaglandin J3 (Δ(12)-PGJ3) Analogues and Related Compounds. Journal of the American Chemical Society. PMID 27171618 DOI: 10.1021/Jacs.6B02075  0.323
2016 Nicolaou KC, Yin J, Mandal D, Erande RD, Klahn P, Jin M, Aujay M, Sandoval J, Gavrilyuk J, Vourloumis D. Total Synthesis and Biological Evaluation of Natural and Designed Tubulysins. Journal of the American Chemical Society. PMID 26829208 DOI: 10.1021/Jacs.5B12557  0.339
2015 Nicolaou KC, Vourloumis D, Totokotsopoulos S, Papakyriakou A, Karsunky H, Fernando H, Gavrilyuk J, Webb D, Stepan AF. Synthesis and Biopharmaceutical Evaluation of Imatinib Analogues Featuring Unusual Structural Motifs. Chemmedchem. PMID 26585829 DOI: 10.1002/Cmdc.201500510  0.338
2014 Asano S, Gavrilyuk J, Burton DR, Barbas CF. Preparation and activities of macromolecule conjugates of the CCR5 antagonist Maraviroc. Acs Medicinal Chemistry Letters. 5: 133-137. PMID 24563723 DOI: 10.1021/Ml400370W  0.393
2013 Ban H, Nagano M, Gavrilyuk J, Hakamata W, Inokuma T, Barbas CF. Facile and stabile linkages through tyrosine: bioconjugation strategies with the tyrosine-click reaction. Bioconjugate Chemistry. 24: 520-32. PMID 23534985 DOI: 10.1021/Bc300665T  0.7
2013 Gavrilyuk J, Ban H, Uehara H, Sirk SJ, Saye-Francisco K, Cuevas A, Zablowsky E, Oza A, Seaman MS, Burton DR, Barbas CF. Antibody conjugation approach enhances breadth and potency of neutralization of anti-HIV-1 antibodies and CD4-IgG. Journal of Virology. 87: 4985-93. PMID 23427154 DOI: 10.1128/Jvi.03146-12  0.627
2012 Gavrilyuk J, Ban H, Nagano M, Hakamata W, Barbas CF. Formylbenzene diazonium hexafluorophosphate reagent for tyrosine-selective modification of proteins and the introduction of a bioorthogonal aldehyde. Bioconjugate Chemistry. 23: 2321-8. PMID 23181702 DOI: 10.1021/Bc300410P  0.659
2010 Gavrilyuk J, Uehara H, Otsubo N, Hessell A, Burton DR, Barbas CF. Potent inhibition of HIV-1 entry with a chemically programmed antibody aided by an efficient organocatalytic synthesis. Chembiochem : a European Journal of Chemical Biology. 11: 2113-8. PMID 20845359 DOI: 10.1002/Cbic.201000432  0.416
2010 Ban H, Gavrilyuk J, Barbas CF. Tyrosine bioconjugation through aqueous ene-type reactions: a click-like reaction for tyrosine. Journal of the American Chemical Society. 132: 1523-5. PMID 20067259 DOI: 10.1021/Ja909062Q  0.519
2010 Smith CD, Gavrilyuk JI, Lough AJ, Batey RA. Lewis Acid catalyzed three-component hetero-Diels-alder (povarov) reaction of N-arylimines with strained norbornene-derived dienophiles. The Journal of Organic Chemistry. 75: 702-15. PMID 20039638 DOI: 10.1021/Jo9021106  0.569
2008 Gavrilyuk JI, Lough AJ, Batey RA. Parallel solution phase synthesis of a library of amino acid derived 2-arylamino-[1,3,4]-oxadiazoles Tetrahedron Letters. 49: 4746-4749. DOI: 10.1016/J.Tetlet.2008.05.110  0.573
2007 Gavrilyuk JI, Evindar G, Chen JY, Batey RA. Peptide-heterocycle hybrid molecules: solid-phase-supported synthesis of substituted N-terminal 5-aminotetrazole peptides via electrocyclization of peptidic imidoylazides. Journal of Combinatorial Chemistry. 9: 644-51. PMID 17580974 DOI: 10.1021/Cc060119P  0.687
2006 Gavrilyuk JI, Evindar G, Batey RA. Peptide-heterocycle hybrid molecules: solid-phase synthesis of a 400-member library of N-terminal 2-iminohydantoin peptides. Journal of Combinatorial Chemistry. 8: 237-46. PMID 16529519 DOI: 10.1021/Cc050090+  0.683
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