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Tasuku Honjo - Publications

Affiliations: 
1979-1984 Genetics Osaka University Medical School 
 1984-2005 Medical Chemistry Kyoto University, Kyōto-shi, Kyōto-fu, Japan 
Area:
Molecular Immunology
Website:
https://kuias.kyoto-u.ac.jp/e/profile/honjo/
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343 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Akrami M, Menzies R, Chamoto K, Miyajima M, Suzuki R, Sato H, Nishii A, Tomura M, Fagarasan S, Honjo T. Circulation of gut-preactivated naïve CD8 T cells enhances antitumor immunity in B cell-defective mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 32907933 DOI: 10.1073/Pnas.2010981117  0.327
2020 Husain A, Xu J, Fujii H, Nakata M, Kobayashi M, Wang JY, Rehwinkel J, Honjo T, Begum NA. SAMHD1-mediated dNTP degradation is required for efficient DNA repair during antibody class switch recombination. The Embo Journal. e102931. PMID 32511795 DOI: 10.15252/Embj.2019102931  0.32
2019 Islam H, Kobayashi M, Honjo T. Apurinic/apyrimidinic endonuclease 1 (APE1) is dispensable for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation in the immunoglobulin gene. International Immunology. PMID 30877298 DOI: 10.1093/Intimm/Dxz028  0.364
2017 Al Ismail A, Husain A, Kobayashi M, Honjo T, Begum NA. Depletion of recombination specific co-factors by the C-terminal mutant of the activation-induced cytidine deaminase causes the dominant negative effect on class switch recombination. International Immunology. PMID 29136157 DOI: 10.1093/Intimm/Dxx061  0.357
2017 McDonald G, Medina CO, Pilichowska M, Kearney JF, Shinkura R, Selsing E, Wortis HH, Honjo T, Imanishi-Kari T. Accelerated Systemic Autoimmunity in the Absence of Somatic Hypermutation in 564Igi: A Mouse Model of Systemic Lupus with Knocked-In Heavy and Light Chain Genes. Frontiers in Immunology. 8: 1094. PMID 28955333 DOI: 10.3389/Fimmu.2017.01094  0.354
2016 Zhang B, Chikuma S, Hori S, Fagarasan S, Honjo T. Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model. Proceedings of the National Academy of Sciences of the United States of America. PMID 27410049 DOI: 10.1073/Pnas.1608873113  0.305
2016 Mondal S, Begum NA, Hu W, Honjo T. Functional requirements of AID's higher order structures and their interaction with RNA-binding proteins. Proceedings of the National Academy of Sciences of the United States of America. PMID 26929374 DOI: 10.1073/Pnas.1601678113  0.31
2016 Husain A, Begum NA, Taniguchi T, Taniguchi H, Kobayashi M, Honjo T. Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instability. Nature Communications. 7: 10549. PMID 26842758 DOI: 10.1038/Ncomms10549  0.312
2015 Hu W, Begum NA, Mondal S, Stanlie A, Honjo T. Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase. Proceedings of the National Academy of Sciences of the United States of America. 112: 5791-6. PMID 25902538 DOI: 10.1073/Pnas.1506167112  0.31
2014 Xu J, Husain A, Hu W, Honjo T, Kobayashi M. APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination. Proceedings of the National Academy of Sciences of the United States of America. 111: 17242-7. PMID 25404348 DOI: 10.1073/Pnas.1420221111  0.311
2014 Yousif AS, Stanlie A, Begum NA, Honjo T. Opinion: uracil DNA glycosylase (UNG) plays distinct and non-canonical roles in somatic hypermutation and class switch recombination. International Immunology. 26: 575-8. PMID 24994819 DOI: 10.1093/Intimm/Dxu071  0.303
2014 Sabouri S, Kobayashi M, Begum NA, Xu J, Hirota K, Honjo T. C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion. Proceedings of the National Academy of Sciences of the United States of America. 111: 2253-8. PMID 24469810 DOI: 10.1073/Pnas.1324057111  0.33
2014 Murakami A, Moriyama H, Osako-Kabasawa M, Endo K, Nishimura M, Udaka K, Muramatsu M, Honjo T, Azuma T, Shimizu T. Low-affinity IgM antibodies lacking somatic hypermutations are produced in the secondary response of C57BL/6 mice to (4-hydroxy-3-nitrophenyl)acetyl hapten. International Immunology. 26: 195-208. PMID 24285827 DOI: 10.1093/Intimm/Dxt057  0.312
2013 Rui Y, Honjo T, Chikuma S. Programmed cell death 1 inhibits inflammatory helper T-cell development through controlling the innate immune response. Proceedings of the National Academy of Sciences of the United States of America. 110: 16073-8. PMID 24043779 DOI: 10.1073/Pnas.1315828110  0.31
2013 Aida M, Honjo T. FACT and H3.3: new markers for the somatic hypermutation. Cell Cycle (Georgetown, Tex.). 12: 2923-4. PMID 23974092 DOI: 10.4161/Cc.26178  0.371
2013 Huong le T, Kobayashi M, Nakata M, Shioi G, Miyachi H, Honjo T, Nagaoka H. In vivo analysis of Aicda gene regulation: a critical balance between upstream enhancers and intronic silencers governs appropriate expression. Plos One. 8: e61433. PMID 23613851 DOI: 10.1371/Journal.Pone.0061433  0.354
2012 Begum NA, Stanlie A, Nakata M, Akiyama H, Honjo T. The histone chaperone Spt6 is required for activation-induced cytidine deaminase target determination through H3K4me3 regulation. The Journal of Biological Chemistry. 287: 32415-29. PMID 22843687 DOI: 10.1074/Jbc.M112.351569  0.313
2012 Begum NA, Honjo T. Evolutionary comparison of the mechanism of DNA cleavage with respect to immune diversity and genomic instability. Biochemistry. 51: 5243-56. PMID 22712724 DOI: 10.1021/Bi3005895  0.319
2012 Stanlie A, Begum NA, Akiyama H, Honjo T. The DSIF subunits Spt4 and Spt5 have distinct roles at various phases of immunoglobulin class switch recombination. Plos Genetics. 8: e1002675. PMID 22570620 DOI: 10.1371/Journal.Pgen.1002675  0.339
2012 Chikuma S, Suita N, Okazaki IM, Shibayama S, Honjo T. TRIM28 prevents autoinflammatory T cell development in vivo. Nature Immunology. 13: 596-603. PMID 22544392 DOI: 10.1038/Ni.2293  0.325
2012 Honjo T, Kobayashi M, Begum N, Kotani A, Sabouri S, Nagaoka H. The AID dilemma: infection, or cancer? Advances in Cancer Research. 113: 1-44. PMID 22429851 DOI: 10.1016/B978-0-12-394280-7.00001-4  0.326
2012 Kato L, Begum NA, Burroughs AM, Doi T, Kawai J, Daub CO, Kawaguchi T, Matsuda F, Hayashizaki Y, Honjo T. Nonimmunoglobulin target loci of activation-induced cytidine deaminase (AID) share unique features with immunoglobulin genes. Proceedings of the National Academy of Sciences of the United States of America. 109: 2479-84. PMID 22308462 DOI: 10.1073/Pnas.1120791109  0.336
2011 Qin H, Suzuki K, Nakata M, Chikuma S, Izumi N, Huong le T, Maruya M, Fagarasan S, Busslinger M, Honjo T, Nagaoka H. Activation-induced cytidine deaminase expression in CD4+ T cells is associated with a unique IL-10-producing subset that increases with age. Plos One. 6: e29141. PMID 22216188 DOI: 10.1371/Journal.Pone.0029141  0.372
2011 Kobayashi M, Sabouri Z, Sabouri S, Kitawaki Y, Pommier Y, Abe T, Kiyonari H, Honjo T. Decrease in topoisomerase I is responsible for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation. Proceedings of the National Academy of Sciences of the United States of America. 108: 19305-10. PMID 22080610 DOI: 10.1073/Pnas.1114522108  0.349
2011 Okazaki IM, Okawa K, Kobayashi M, Yoshikawa K, Kawamoto S, Nagaoka H, Shinkura R, Kitawaki Y, Taniguchi H, Natsume T, Iemura S, Honjo T. Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation. Proceedings of the National Academy of Sciences of the United States of America. 108: 7920-5. PMID 21518874 DOI: 10.1073/Pnas.1104423108  0.337
2011 Gutierrez FR, Mariano FS, Oliveira CJ, Pavanelli WR, Guedes PM, Silva GK, Campanelli AP, Milanezi CM, Azuma M, Honjo T, Teixeira MM, Aliberti JC, Silva JS. Regulation of Trypanosoma cruzi-induced myocarditis by programmed death cell receptor 1. Infection and Immunity. 79: 1873-81. PMID 21357717 DOI: 10.1128/Iai.01047-10  0.309
2011 Okazaki T, Okazaki IM, Wang J, Sugiura D, Nakaki F, Yoshida T, Kato Y, Fagarasan S, Muramatsu M, Eto T, Hioki K, Honjo T. PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice. The Journal of Experimental Medicine. 208: 395-407. PMID 21300912 DOI: 10.1084/Jem.20100466  0.336
2011 Terawaki S, Chikuma S, Shibayama S, Hayashi T, Yoshida T, Okazaki T, Honjo T. IFN-α directly promotes programmed cell death-1 transcription and limits the duration of T cell-mediated immunity. Journal of Immunology (Baltimore, Md. : 1950). 186: 2772-9. PMID 21263073 DOI: 10.4049/Jimmunol.1003208  0.321
2010 Stanlie A, Aida M, Muramatsu M, Honjo T, Begum NA. Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination. Proceedings of the National Academy of Sciences of the United States of America. 107: 22190-5. PMID 21139053 DOI: 10.1073/Pnas.1016923108  0.326
2010 Jeannet R, Mastio J, Macias-Garcia A, Oravecz A, Ashworth T, Geimer Le Lay AS, Jost B, Le Gras S, Ghysdael J, Gridley T, Honjo T, Radtke F, Aster JC, Chan S, Kastner P. Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL. Blood. 116: 5443-54. PMID 20829372 DOI: 10.1182/Blood-2010-05-286658  0.356
2010 Tanigaki K, Honjo T. Two opposing roles of RBP-J in Notch signaling. Current Topics in Developmental Biology. 92: 231-52. PMID 20816397 DOI: 10.1016/S0070-2153(10)92007-3  0.328
2010 Wang J, Okazaki IM, Yoshida T, Chikuma S, Kato Y, Nakaki F, Hiai H, Honjo T, Okazaki T. PD-1 deficiency results in the development of fatal myocarditis in MRL mice. International Immunology. 22: 443-52. PMID 20410257 DOI: 10.1093/Intimm/Dxq026  0.33
2010 Komeno Y, Kitaura J, Watanabe-Okochi N, Kato N, Oki T, Nakahara F, Harada Y, Harada H, Shinkura R, Nagaoka H, Hayashi Y, Honjo T, Kitamura T. AID-induced T-lymphoma or B-leukemia/lymphoma in a mouse BMT model. Leukemia. 24: 1018-24. PMID 20357822 DOI: 10.1038/Leu.2010.40  0.334
2010 Nagaoka H, Tran TH, Kobayashi M, Aida M, Honjo T. Preventing AID, a physiological mutator, from deleterious activation: regulation of the genomic instability that is associated with antibody diversity. International Immunology. 22: 227-35. PMID 20207715 DOI: 10.1093/Intimm/Dxq023  0.332
2010 Tran TH, Nakata M, Suzuki K, Begum NA, Shinkura R, Fagarasan S, Honjo T, Nagaoka H. B cell-specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers. Nature Immunology. 11: 148-54. PMID 19966806 DOI: 10.1038/Ni.1829  0.344
2009 Kobayashi M, Aida M, Nagaoka H, Begum NA, Kitawaki Y, Nakata M, Stanlie A, Doi T, Kato L, Okazaki IM, Shinkura R, Muramatsu M, Kinoshita K, Honjo T. AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination. Proceedings of the National Academy of Sciences of the United States of America. 106: 22375-80. PMID 20018730 DOI: 10.1073/Pnas.0911879106  0.324
2009 Sabouri Z, Okazaki IM, Shinkura R, Begum N, Nagaoka H, Tsuchimoto D, Nakabeppu Y, Honjo T. Apex2 is required for efficient somatic hypermutation but not for class switch recombination of immunoglobulin genes. International Immunology. 21: 947-55. PMID 19556307 DOI: 10.1093/Intimm/Dxp061  0.363
2009 Chikuma S, Terawaki S, Hayashi T, Nabeshima R, Yoshida T, Shibayama S, Okazaki T, Honjo T. PD-1-mediated suppression of IL-2 production induces CD8+ T cell anergy in vivo. Journal of Immunology (Baltimore, Md. : 1950). 182: 6682-9. PMID 19454662 DOI: 10.4049/Jimmunol.0900080  0.319
2009 Tsuji M, Komatsu N, Kawamoto S, Suzuki K, Kanagawa O, Honjo T, Hori S, Fagarasan S. Preferential generation of follicular B helper T cells from Foxp3+ T cells in gut Peyer's patches. Science (New York, N.Y.). 323: 1488-92. PMID 19286559 DOI: 10.1126/Science.1169152  0.327
2009 Doi T, Kato L, Ito S, Shinkura R, Wei M, Nagaoka H, Wang J, Honjo T. The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination. Proceedings of the National Academy of Sciences of the United States of America. 106: 2758-63. PMID 19202055 DOI: 10.1073/Pnas.0813253106  0.331
2009 Begum NA, Stanlie A, Doi T, Sasaki Y, Jin HW, Kim YS, Nagaoka H, Honjo T. Further evidence for involvement of a noncanonical function of uracil DNA glycosylase in class switch recombination. Proceedings of the National Academy of Sciences of the United States of America. 106: 2752-7. PMID 19202054 DOI: 10.1073/Pnas.0813252106  0.305
2009 Takai A, Toyoshima T, Uemura M, Kitawaki Y, Marusawa H, Hiai H, Yamada S, Okazaki IM, Honjo T, Chiba T, Kinoshita K. A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations. Oncogene. 28: 469-78. PMID 18997814 DOI: 10.1038/Onc.2008.415  0.302
2008 Morisawa T, Marusawa H, Ueda Y, Iwai A, Okazaki IM, Honjo T, Chiba T. Organ-specific profiles of genetic changes in cancers caused by activation-induced cytidine deaminase expression. International Journal of Cancer. 123: 2735-40. PMID 18781563 DOI: 10.1002/Ijc.23853  0.308
2008 Riccio O, van Gijn ME, Bezdek AC, Pellegrinet L, van Es JH, Zimber-Strobl U, Strobl LJ, Honjo T, Clevers H, Radtke F. Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2 Embo Reports. 9: 377-383. PMID 18274550 DOI: 10.1038/Embor.2008.7  0.313
2008 Green KA, Okazaki T, Honjo T, Cook WJ, Green WR. The programmed death-1 and interleukin-10 pathways play a down-modulatory role in LP-BM5 retrovirus-induced murine immunodeficiency syndrome. Journal of Virology. 82: 2456-69. PMID 18094175 DOI: 10.1128/Jvi.01665-07  0.312
2008 Pasqualucci L, Bhagat G, Jankovic M, Compagno M, Smith P, Muramatsu M, Honjo T, Morse HC, Nussenzweig MC, Dalla-Favera R. AID is required for germinal center-derived lymphomagenesis. Nature Genetics. 40: 108-12. PMID 18066064 DOI: 10.1038/Ng.2007.35  0.354
2007 Kovalchuk AL, duBois W, Mushinski E, McNeil NE, Hirt C, Qi CF, Li Z, Janz S, Honjo T, Muramatsu M, Ried T, Behrens T, Potter M. AID-deficient Bcl-xL transgenic mice develop delayed atypical plasma cell tumors with unusual Ig/Myc chromosomal rearrangements. The Journal of Experimental Medicine. 204: 2989-3001. PMID 17998390 DOI: 10.1084/Jem.20070882  0.318
2007 Komine O, Nagaoka M, Watase K, Gutmann DH, Tanigaki K, Honjo T, Radtke F, Saito T, Chiba S, Tanaka K. The monolayer formation of Bergmann glial cells is regulated by Notch/RBP-J signaling. Developmental Biology. 311: 238-50. PMID 17915208 DOI: 10.1016/J.Ydbio.2007.08.042  0.308
2007 Okazaki IM, Kotani A, Honjo T. Role of AID in tumorigenesis. Advances in Immunology. 94: 245-73. PMID 17560277 DOI: 10.1016/S0065-2776(06)94008-5  0.37
2007 Takebayashi S, Yamamoto N, Yabe D, Fukuda H, Kojima K, Ito J, Honjo T. Multiple roles of Notch signaling in cochlear development. Developmental Biology. 307: 165-78. PMID 17531970 DOI: 10.1016/J.Ydbio.2007.04.035  0.31
2007 Yabe D, Fukuda H, Aoki M, Yamada S, Takebayashi S, Shinkura R, Yamamoto N, Honjo T. Generation of a conditional knockout allele for mammalian Spen protein Mint/SHARP. Genesis (New York, N.Y. : 2000). 45: 300-6. PMID 17457934 DOI: 10.1002/Dvg.20296  0.325
2007 Tanigaki K, Honjo T. Regulation of lymphocyte development by Notch signaling. Nature Immunology. 8: 451-6. PMID 17440450 DOI: 10.1038/Ni1453  0.332
2007 Endo Y, Marusawa H, Kinoshita K, Morisawa T, Sakurai T, Okazaki IM, Watashi K, Shimotohno K, Honjo T, Chiba T. Expression of activation-induced cytidine deaminase in human hepatocytes via NF-κB signaling Oncogene. 26: 5587-5595. PMID 17404578 DOI: 10.1038/Sj.Onc.1210344  0.329
2007 Shinkura R, Okazaki IM, Muto T, Begum NA, Honjo T. Regulation of AID function in vivo. Advances in Experimental Medicine and Biology. 596: 71-81. PMID 17338177 DOI: 10.1007/0-387-46530-8_7  0.402
2007 Kumazaki K, Tirosh B, Maehr R, Boes M, Honjo T, Ploegh HL. AID-/-μs-/- mice are agammaglobulinemic and fail to maintain B220-CD138+ plasma cells Journal of Immunology. 178: 2192-2203. PMID 17277124 DOI: 10.4049/Jimmunol.178.4.2192  0.347
2007 Kotani A, Kakazu N, Tsuruyama T, Okazaki IM, Muramatsu M, Kinoshita K, Nagaoka H, Yabe D, Honjo T. Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 1616-20. PMID 17251349 DOI: 10.1073/Pnas.0610732104  0.371
2007 Tsuji M, Shinkura R, Kuroda K, Yabe D, Honjo T. Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling. Proceedings of the National Academy of Sciences of the United States of America. 104: 1610-5. PMID 17242367 DOI: 10.1073/Pnas.0610520104  0.304
2006 Tanaka S, Tsukada J, Suzuki W, Hayashi K, Tanigaki K, Tsuji M, Inoue H, Honjo T, Kubo M. The interleukin-4 enhancer CNS-2 is regulated by Notch signals and controls initial expression in NKT cells and memory-type CD4 T cells. Immunity. 24: 689-701. PMID 16782026 DOI: 10.1016/J.Immuni.2006.04.009  0.307
2006 Ikuta K, Kageyama R, Honjo T. The 20th IUBMB International Congress in Kyoto. Iubmb Life. 58: 258. PMID 16754309 DOI: 10.1080/15216540600719663  0.5
2006 Wang J, Shinkura R, Muramatsu M, Nagaoka H, Kinoshita K, Honjo T. Identification of a specific domain required for dimerization of activation-induced cytidine deaminase. The Journal of Biological Chemistry. 281: 19115-23. PMID 16687409 DOI: 10.1074/Jbc.M601645200  0.318
2006 Buono KD, Robinson GW, Martin C, Shi S, Stanley P, Tanigaki K, Honjo T, Hennighausen L. The canonical Notch/RBP-J signaling pathway controls the balance of cell lineages in mammary epithelium during pregnancy. Developmental Biology. 293: 565-80. PMID 16581056 DOI: 10.1016/J.Ydbio.2006.02.043  0.321
2006 Muto T, Okazaki IM, Yamada S, Tanaka Y, Kinoshita K, Muramatsu M, Nagaoka H, Honjo T. Negative regulation of activation-induced cytidine deaminase in B cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 2752-7. PMID 16477013 DOI: 10.1073/Pnas.0510970103  0.363
2006 Fujikura J, Hosoda K, Iwakura H, Tomita T, Noguchi M, Masuzaki H, Tanigaki K, Yabe D, Honjo T, Nakao K. Notch/Rbp-j signaling prevents premature endocrine and ductal cell differentiation in the pancreas. Cell Metabolism. 3: 59-65. PMID 16399505 DOI: 10.1016/J.Cmet.2005.12.005  0.315
2006 Wakae K, Magor BG, Saunders H, Nagaoka H, Kawamura A, Kinoshita K, Honjo T, Muramatsu M. Evolution of class switch recombination function in fish activation-induced cytidine deaminase, AID. International Immunology. 18: 41-7. PMID 16291656 DOI: 10.1093/Intimm/Dxh347  0.379
2006 Yamamoto N, Tanigaki K, Tsuji M, Yabe D, Ito J, Honjo T. Inhibition of Notch/RBP-J signaling induces hair cell formation in neonate mouse cochleas. Journal of Molecular Medicine (Berlin, Germany). 84: 37-45. PMID 16283144 DOI: 10.1007/S00109-005-0706-9  0.307
2005 Okazaki T, Otaka Y, Wang J, Hiai H, Takai T, Ravetch JV, Honjo T. Hydronephrosis associated with antiurothelial and antinuclear autoantibodies in BALB/c-Fcgr2b-/-Pdcd1-/- mice. The Journal of Experimental Medicine. 202: 1643-8. PMID 16352741 DOI: 10.1084/Jem.20051984  0.314
2005 Xin H, Kikuchi T, Andarini S, Ohkouchi S, Suzuki T, Nukiwa T, Huqun, Hagiwara K, Honjo T, Saijo Y. Antitumor immune response by CX3CL1 fractalkine gene transfer depends on both NK and T cells European Journal of Immunology. 35: 1371-1380. PMID 15789339 DOI: 10.1002/Eji.200526042  0.325
2005 Kotani A, Okazaki IM, Muramatsu M, Kinoshita K, Begum NA, Nakajima T, Saito H, Honjo T. A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression. Proceedings of the National Academy of Sciences of the United States of America. 102: 4506-11. PMID 15767564 DOI: 10.1073/Pnas.0500830102  0.362
2005 Suzuki K, Meek B, Doi Y, Honjo T, Fagarasan S. Two distinctive pathways for recruitment of naive and primed IgM+ B cells to the gut lamina propria. Proceedings of the National Academy of Sciences of the United States of America. 102: 2482-6. PMID 15695334 DOI: 10.1073/Pnas.0409539102  0.31
2004 Iwai Y, Terawaki S, Honjo T. PD-1 blockade inhibits hematogenous spread of poorly immunogenic tumor cells by enhanced recruitment of effector T cells International Immunology. 17: 133-144. PMID 15611321 DOI: 10.1093/Intimm/Dxh194  0.324
2004 Michishita M, Ikeda T, Nakashiba T, Ogawa M, Tashiro K, Honjo T, Doi K, Itohara S, Endo S. Expression of Btcl2, a novel member of Btcl gene family, during development of the central nervous system. Brain Research. Developmental Brain Research. 153: 135-42. PMID 15464227 DOI: 10.1016/J.Devbrainres.2004.06.012  0.305
2004 Ramiro AR, Jankovic M, Eisenreich T, Difilippantonio S, Chen-Kiang S, Muramatsu M, Honjo T, Nussenzweig A, Nussenzweig MC. AID is required for c-myc/IgH chromosome translocations in vivo. Cell. 118: 431-8. PMID 15315756 DOI: 10.1016/J.Cell.2004.08.006  0.316
2004 Shinkura R, Ito S, Begum NA, Nagaoka H, Muramatsu M, Kinoshita K, Sakakibara Y, Hijikata H, Honjo T. Separate domains of AID are required for somatic hypermutation and class-switch recombination. Nature Immunology. 5: 707-12. PMID 15195091 DOI: 10.1038/Ni1086  0.312
2004 Tanigaki K, Tsuji M, Yamamoto N, Han H, Tsukada J, Inoue H, Kubo M, Honjo T. Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling. Immunity. 20: 611-22. PMID 15142529 DOI: 10.1016/S1074-7613(04)00109-8  0.313
2004 Amsen D, Blander JM, Lee GR, Tanigaki K, Honjo T, Flavell RA. Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells. Cell. 117: 515-26. PMID 15137944 DOI: 10.1016/S0092-8674(04)00451-9  0.311
2004 Horiguchi S, Takahashi J, Kishi Y, Morizane A, Okamoto Y, Koyanagi M, Tsuji M, Tashiro K, Honjo T, Fujii S, Hashimoto N. Neural precursor cells derived from human embryonic brain retain regional specificity. Journal of Neuroscience Research. 75: 817-24. PMID 14994342 DOI: 10.1002/Jnr.20046  0.301
2004 Blank C, Brown I, Peterson AC, Spiotto M, Iwai Y, Honjo T, Gajewski TF. PD-L1/B7H-1 inhibits the effector phase of tumor rejection by T cell receptor (TCR) transgenic CD8+ T cells. Cancer Research. 64: 1140-5. PMID 14871849 DOI: 10.1158/0008-5472.Can-03-3259  0.331
2004 Ito S, Nagaoka H, Shinkura R, Begum N, Muramatsu M, Nakata M, Honjo T. Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1. Proceedings of the National Academy of Sciences of the United States of America. 101: 1975-80. PMID 14769937 DOI: 10.1073/Pnas.0307335101  0.339
2004 Blank C, Brown I, Marks R, Nishimura H, Honjo T, Gajewski TF. Absence of programmed death receptor 1 alters thymic development and enhances generation of CD4/CD8 double-negative TCR-transgenic T cells. Journal of Immunology (Baltimore, Md. : 1950). 171: 4574-81. PMID 14568931 DOI: 10.4049/Jimmunol.171.9.4574  0.342
2004 Tanigaki K, Kuroda K, Han H, Honjo T. Regulation of B cell development by Notch/RBP-J signaling. Seminars in Immunology. 15: 113-9. PMID 12681948 DOI: 10.1016/S1044-5323(03)00008-3  0.338
2003 Eto T, Kinoshita K, Yoshikawa K, Muramatsu M, Honjo T. RNA-editing cytidine deaminase Apobec-1 is unable to induce somatic hypermutation in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 12895-8. PMID 14559972 DOI: 10.1073/Pnas.2135587100  0.325
2003 Ta VT, Nagaoka H, Catalan N, Durandy A, Fischer A, Imai K, Nonoyama S, Tashiro J, Ikegawa M, Ito S, Kinoshita K, Muramatsu M, Honjo T. AID mutant analyses indicate requirement for class-switch-specific cofactors. Nature Immunology. 4: 843-8. PMID 12910268 DOI: 10.1038/Ni964  0.309
2003 Okazaki I, Hiai H, Kakazu N, Yamada S, Muramatsu M, Kinoshita K, Honjo T. Constitutive Expression of AID Leads to Tumorigenesis Journal of Experimental Medicine. 197: 1173-1181. PMID 12732658 DOI: 10.1084/Jem.20030275  0.385
2003 Okazaki I, Yoshikawa K, Kinoshita K, Muramatsu M, Nagaoka H, Honjo T. Activation-induced cytidine deaminase links class switch recombination and somatic hypermutation. Annals of the New York Academy of Sciences. 987: 1-8. PMID 12727618 DOI: 10.1111/J.1749-6632.2003.Tb06027.X  0.351
2003 Schroeder T, Fraser ST, Ogawa M, Nishikawa S, Oka C, Bornkamm GW, Nishikawa SI, Honjo T, Just U. Recombination signal sequence-binding protein Jκ alters mesodermal cell fate decisions by suppressing cardiomyogenesis Proceedings of the National Academy of Sciences of the United States of America. 100: 4018-4023. PMID 12655061 DOI: 10.1073/Pnas.0438008100  0.342
2003 Watanabe N, Ikuta K, Okazaki K, Nakase H, Tabata Y, Matsuura M, Tamaki H, Kawanami C, Honjo T, Chiba T. Elimination of local macrophages in intestine prevents chronic colitis in interleukin-10-deficient mice. Digestive Diseases and Sciences. 48: 408-14. PMID 12643623 DOI: 10.1023/A:1021960401290  0.539
2003 Kuroda K, Han H, Tani S, Tanigaki K, Tun T, Furukawa T, Taniguchi Y, Kurooka H, Hamada Y, Toyokuni S, Honjo T. Regulation of marginal zone B cell development by MINT, a suppressor of Notch/RBP-J signaling pathway. Immunity. 18: 301-12. PMID 12594956 DOI: 10.1016/S1074-7613(03)00029-3  0.341
2003 Yamamoto N, Tanigaki K, Han H, Hiai H, Honjo T. Notch/RBP-J signaling regulates epidermis/hair fate determination of hair follicular stem cells. Current Biology : Cb. 13: 333-8. PMID 12593800 DOI: 10.1016/S0960-9822(03)00081-2  0.313
2003 Doi T, Kinoshita K, Ikegawa M, Muramatsu M, Honjo T. De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination. Proceedings of the National Academy of Sciences of the United States of America. 100: 2634-8. PMID 12591955 DOI: 10.1073/Pnas.0437710100  0.343
2003 Zhu Y, Nonoyama S, Morio T, Muramatsu M, Honjo T, Mizutani S. Type two hyper-IgM syndrome caused by mutation in activation-induced cytidine deaminase. Journal of Medical and Dental Sciences. 50: 41-46. DOI: 10.11480/Jmds.500106  0.319
2002 Fagarasan S, Muramatsu M, Suzuki K, Nagaoka H, Hiai H, Honjo T. Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora. Science (New York, N.Y.). 298: 1424-7. PMID 12434060 DOI: 10.1126/Science.1077336  0.337
2002 Watanabe N, Ikuta K, Nisitani S, Chiba T, Honjo T. Activation and differentiation of autoreactive B-1 cells by interleukin 10 induce autoimmune hemolytic anemia in Fas-deficient antierythrocyte immunoglobulin transgenic mice. The Journal of Experimental Medicine. 196: 141-6. PMID 12093879 DOI: 10.1084/Jem.20011519  0.6
2002 Yoshikawa K, Okazaki IM, Eto T, Kinoshita K, Muramatsu M, Nagaoka H, Honjo T. AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts. Science (New York, N.Y.). 296: 2033-6. PMID 12065838 DOI: 10.1126/Science.1071556  0.382
2002 Han H, Tanigaki K, Yamamoto N, Kuroda K, Yoshimoto M, Nakahata T, Ikuta K, Honjo T. Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision. International Immunology. 14: 637-45. PMID 12039915 DOI: 10.1093/Intimm/Dxf030  0.618
2002 Bross L, Muramatsu M, Kinoshita K, Honjo T, Jacobs H. DNA double-strand breaks: prior to but not sufficient in targeting hypermutation. Journal of Experimental Medicine. 195: 1187-1192. PMID 11994423 DOI: 10.1084/Jem.20011749  0.336
2002 Tanigaki K, Han H, Yamamoto N, Tashiro K, Ikegawa M, Kuroda K, Suzuki A, Nakano T, Honjo T. Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cells. Nature Immunology. 3: 443-50. PMID 11967543 DOI: 10.1038/Ni793  0.345
2002 Okazaki IM, Kinoshita K, Muramatsu M, Yoshikawa K, Honjo T. The AID enzyme induces class switch recombination in fibroblasts. Nature. 416: 340-5. PMID 11875397 DOI: 10.1038/Nature727  0.394
2002 Honjo T, Kinoshita K, Muramatsu M. Molecular Mechanism of Class Switch Recombination: Linkage with Somatic Hypermutation Annual Review of Immunology. 20: 165-196. PMID 11861601 DOI: 10.1146/Annurev.Immunol.20.090501.112049  0.318
2002 Nagaoka H, Muramatsu M, Yamamura N, Kinoshita K, Honjo T. Activation-induced deaminase (AID)-directed hypermutation in the immunoglobulin Smu region: implication of AID involvement in a common step of class switch recombination and somatic hypermutation. The Journal of Experimental Medicine. 195: 529-34. PMID 11854365 DOI: 10.1084/Jem.20012144  0.346
2002 Kanatsu-Shinohara M, Ogura A, Ikegawa M, Inoue K, Ogonuki N, Tashiro K, Toyokuni S, Honjo T, Shinohara T. Adenovirus-mediated gene delivery and in vitro microinsemination produce offspring from infertile male mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 1383-1388. PMID 11818536 DOI: 10.1073/Pnas.022646399  0.347
2002 Higuchi T, Aiba Y, Nomura T, Matsuda J, Mochida K, Suzuki M, Kikutani H, Honjo T, Nishioka K, Tsubata T. Cutting Edge: Ectopic Expression of CD40 Ligand on B Cells Induces Lupus-Like Autoimmune Disease Journal of Immunology. 168: 9-12. PMID 11751940 DOI: 10.4049/Jimmunol.168.1.9  0.332
2002 Chen X, Kinoshita K, Honjo T. Variable deletion and duplication at recombination junction ends: implication for staggered double-strand cleavage in class-switch recombination. Proceedings of the National Academy of Sciences of the United States of America. 98: 13860-5. PMID 11717442 DOI: 10.1073/Pnas.241524898  0.327
2001 Petersen S, Casellas R, Reina-San-Martin B, Chen HT, Difilippantonio MJ, Wilson PC, Hanitsch L, Celeste A, Muramatsu M, Pilch DR, Redon C, Ried T, Bonner WM, Honjo T, Nussenzweig MC, et al. AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching Nature. 414: 660-665. PMID 11740565 DOI: 10.1038/414660A  0.354
2001 Ye SK, Agata Y, Lee HC, Kurooka H, Kitamura T, Shimizu A, Honjo T, Ikuta K. The IL-7 receptor controls the accessibility of the TCRgamma locus by Stat5 and histone acetylation. Immunity. 15: 813-23. PMID 11728342 DOI: 10.1016/S1074-7613(01)00230-8  0.554
2001 Okazaki T, Maeda A, Nishimura H, Kurosaki T, Honjo T. PD-1 Immunoreceptor Inhibits B Cell Receptor-Mediated Signaling by Recruiting Src Homology 2-domain-containing Tyrosine Phosphatase 2 to Phosphotyrosine Proceedings of the National Academy of Sciences of the United States of America. 98: 13866-13871. PMID 11698646 DOI: 10.1073/Pnas.231486598  0.301
2001 Fagarasan S, Kinoshita K, Muramatsu M, Ikuta K, Honjo T. In situ class switching and differentiation to IgA-producing cells in the gut lamina propria. Nature. 413: 639-43. PMID 11675788 DOI: 10.1038/35098100  0.616
2001 Kinoshita K, Harigai M, Fagarasan S, Muramatsu M, Honjo T. A hallmark of active class switch recombination: transcripts directed by I promoters on looped-out circular DNAs. Proceedings of the National Academy of Sciences of the United States of America. 98: 12620-3. PMID 11606740 DOI: 10.1073/Pnas.221454398  0.337
2001 Ye SK, Maki K, Lee HC, Ito A, Kawai K, Suzuki H, Mak TW, Chien Y, Honjo T, Ikuta K. Differential roles of cytokine receptors in the development of epidermal gamma delta T cells. Journal of Immunology (Baltimore, Md. : 1950). 167: 1929-34. PMID 11489972 DOI: 10.4049/Jimmunol.167.4.1929  0.579
2001 Lee C, Kinoshita K, Arudchandran A, Cerritelli SM, Crouch RJ, Honjo T. Quantitative regulation of class switch recombination by switch region transcription. Journal of Experimental Medicine. 194: 365-374. PMID 11489955 DOI: 10.1084/Jem.194.3.365  0.307
2001 Kobuke K, Furukawa Y, Sugai M, Tanigaki K, Ohashi N, Matsumori A, Sasayama S, Honjo T, Tashiro K. ESDN, a novel neuropilin-like membrane protein cloned from vascular cells with the longest secretory signal sequence among eukaryotes, is up-regulated after vascular injury. Journal of Biological Chemistry. 276: 34105-34114. PMID 11447234 DOI: 10.1074/Jbc.M105293200  0.324
2001 Lee HC, Ye SK, Honjo T, Ikuta K. Induction of germline transcription in the human TCR gamma locus by STAT5. Journal of Immunology (Baltimore, Md. : 1950). 167: 320-6. PMID 11418666 DOI: 10.4049/Jimmunol.167.1.320  0.601
2001 Agata Y, Katakai T, Ye SK, Sugai M, Gonda H, Honjo T, Ikuta K, Shimizu A. Histone acetylation determines the developmentally regulated accessibility for T cell receptor gamma gene recombination. The Journal of Experimental Medicine. 193: 873-80. PMID 11283160 DOI: 10.1084/Jem.193.7.873  0.576
2001 Tani S, Kurooka H, Aoki T, Hashimoto N, Honjo T. The N- and C-terminal regions of RBP-J interact with the ankyrin repeats of Notch1 RAMIC to activate transcription Nucleic Acids Research. 29: 1373-1380. PMID 11239004 DOI: 10.1093/Nar/29.6.1373  0.321
2001 Watanabe N, Ikuta K, Fagarasan S, Yazumi S, Chiba T, Honjo T. Migration and differentiation of autoreactive B-1 cells induced by activated gamma/delta T cells in antierythrocyte immunoglobulin transgenic mice. The Journal of Experimental Medicine. 192: 1577-86. PMID 11104800 DOI: 10.1084/Jem.192.11.1577  0.611
2001 Muto T, Muramatsu M, Taniwaki M, Kinoshita K, Honjo T. Isolation, tissue distribution, and chromosomal localization of the human activation-induced cytidine deaminase (AID) gene. Genomics. 68: 85-8. PMID 10950930 DOI: 10.1006/Geno.2000.6268  0.348
2000 Fagarasan S, Shinkura R, Kamata T, Nogaki F, Ikuta K, Honjo T. Mechanism of B1 cell differentiation and migration in GALT. Current Topics in Microbiology and Immunology. 252: 221-229. PMID 11125479 DOI: 10.1007/978-3-642-57284-5_23  0.563
2000 Fagarasan S, Watanabe N, Honjo T. Generation, expansion, migration and activation of mouse B1 cells. Immunological Reviews. 176: 205-215. PMID 11043779 DOI: 10.1034/J.1600-065X.2000.00604.X  0.368
2000 Fagarasan S, Honjo T. T-Independent Immune Response: New Aspects of B Cell Biology Science. 290: 89-92. PMID 11021805 DOI: 10.1126/Science.290.5489.89  0.33
2000 Revy P, Muto T, Levy Y, Geissmann F, Plebani A, Sanal O, Catalan N, Forveille M, Dufourcq-Labelouse R, Gennery A, Tezcan I, Ersoy F, Kayserili H, Ugazio AG, Brousse N, ... ... Honjo T, et al. Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2). Cell. 102: 565-75. PMID 11007475 DOI: 10.1016/S0092-8674(00)00079-9  0.342
2000 Muramatsu M, Kinoshita K, Fagarasan S, Yamada S, Shinkai Y, Honjo T. Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme Cell. 102: 553-563. PMID 11007474 DOI: 10.1016/S0092-8674(00)00078-7  0.345
2000 Yanagawa S, Lee J, Kakimi K, Matsuda Y, Honjo T, Ishimoto A. Identification of Notch1 as a Frequent Target for Provirus Insertional Mutagenesis in T-Cell Lymphomas Induced by Leukemogenic Mutants of Mouse Mammary Tumor Virus Journal of Virology. 74: 9786-9791. PMID 11000255 DOI: 10.1128/Jvi.74.20.9786-9791.2000  0.336
2000 Kamata T, Nogaki F, Fagarasan S, Sakiyama T, Kobayashi I, Miyawaki S, Ikuta K, Muso E, Yoshida H, Sasayama S, Honjo T. Increased frequency of surface IgA-positive plasma cells in the intestinal lamina propria and decreased IgA excretion in hyper IgA (HIGA) mice, a murine model of IgA nephropathy with hyperserum IgA. Journal of Immunology (Baltimore, Md. : 1950). 165: 1387-94. PMID 10903742 DOI: 10.4049/Jimmunol.165.3.1387  0.568
2000 Fagarasan S, Shinkura R, Kamata T, Nogaki F, Ikuta K, Tashiro K, Honjo T. Alymphoplasia (aly)-type nuclear factor kappaB-inducing kinase (NIK) causes defects in secondary lymphoid tissue chemokine receptor signaling and homing of peritoneal cells to the gut-associated lymphatic tissue system. The Journal of Experimental Medicine. 191: 1477-86. PMID 10790423 DOI: 10.1084/Jem.191.9.1477  0.604
2000 Kurooka H, Honjo T. Functional Interaction between the Mouse Notch1 Intracellular Region and Histone Acetyltransferases PCAF and GCN5 Journal of Biological Chemistry. 275: 17211-17220. PMID 10747963 DOI: 10.1074/Jbc.M000909200  0.328
2000 Ono SJ, Zhou G, Tai AK, Inaba M, Kinoshita K, Honjo T. Identification of a stimulus-dependent DNase I hypersensitive site between the Ialpha and Calpha exons during immunoglobulin heavy chain class switch recombination. Febs Letters. 467: 268-72. PMID 10675552 DOI: 10.1016/S0014-5793(00)01151-0  0.306
2000 Kato K, Morrison AM, Nakano T, Tashiro K, Honjo T. ESOP-1, a secreted protein expressed in the hematopoietic, nervous, and reproductive systems of embryonic and adult mice Blood. 96: 362-364. DOI: 10.1182/Blood.V96.1.362.013K23_362_364  0.309
2000 Schroeder T, Fraser S, Oka C, Bornkamm G, Nishikawa S-, Honjo T, Just U. Disruption of the mouse rbp-j gene alters differentiation of cell lineages derived from mesoderm Experimental Hematology. 28: 1496. DOI: 10.1016/S0301-472X(00)00571-3  0.318
1999 Nisitani S, Honjo T. Breakage of B Cell Tolerance and Autoantibody Production in Anti-erythrocyte Transgenic Mice International Reviews of Immunology. 18: 259-270. PMID 10614728 DOI: 10.3109/08830189909043029  0.352
1999 Ochi H, Takeshita H, Suda T, Nisitani S, Honjo T, Watanabe T. Regulation of B-1 cell activation and its autoantibody production by Lyn kinase-regulated signallings Immunology. 98: 595-603. PMID 10594694 DOI: 10.1046/J.1365-2567.1999.00899.X  0.362
1999 Minoguchi S, Ikeda T, Itohara S, Kaneko T, Okaichi H, Honjo T. Studies on the cell-type specific expression of RBP-L, a RBP-J family member, by replacement insertion of beta-galactosidase. Journal of Biochemistry. 126: 738-47. PMID 10502683 DOI: 10.1093/Oxfordjournals.Jbchem.A022511  0.337
1999 Ye SK, Maki K, Kitamura T, Sunaga S, Akashi K, Domen J, Weissman IL, Honjo T, Ikuta K. Induction of germline transcription in the TCRgamma locus by Stat5: implications for accessibility control by the IL-7 receptor. Immunity. 11: 213-23. PMID 10485656 DOI: 10.1016/S1074-7613(00)80096-5  0.64
1999 Nishimura H, Nose M, Hiai H, Minato N, Honjo T. Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity. 11: 141-151. PMID 10485649 DOI: 10.1016/S1074-7613(00)80089-8  0.31
1999 Apelqvist A, Li H, Sommer L, Beatus P, Anderson DJ, Honjo T, Hrabe de Angelis M, Lendahl U, Edlund H. Notch signalling controls pancreatic cell differentiation. Nature. 400: 877-81. PMID 10476967 DOI: 10.1038/23716  0.321
1999 Watanabe N, Nisitani S, Ikuta K, Suzuki M, Chiba T, Honjo T. Expression levels of B cell surface immunoglobulin regulate efficiency of allelic exclusion and size of autoreactive B-1 cell compartment. The Journal of Experimental Medicine. 190: 461-69. PMID 10449517 DOI: 10.1084/Jem.190.4.461  0.602
1999 Lee J, Ishimoto A, Honjo T, Yanagawa S. Murine leukemia provirus-mediated activation of the Notch1 gene leads to induction of HES-1 in a mouse T lymphoma cell line, DL-3 Febs Letters. 455: 276-280. PMID 10437788 DOI: 10.1016/S0014-5793(99)00901-1  0.354
1999 Kanazawa N, Nakamura T, Tashiro K, Muramatsu M, Morita K, Yoneda K, Inaba K, Imamura S, Honjo T. Fractalkine and macrophage-derived chemokine: T cell-attracting chemokines expressed in T cell area dendritic cells. European Journal of Immunology. 29: 1925-1932. PMID 10382755 DOI: 10.1002/(Sici)1521-4141(199906)29:06<1925::Aid-Immu1925>3.0.Co;2-U  0.317
1999 Muramatsu M, Sankaranand VS, Anant S, Sugai M, Kinoshita K, Davidson NO, Honjo T. Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells. The Journal of Biological Chemistry. 274: 18470-6. PMID 10373455 DOI: 10.1074/Jbc.274.26.18470  0.371
1999 Sakiyama T, Ikuta K, Nisitani S, Takatsu K, Honjo T. Requirement of IL-5 for induction of autoimmune hemolytic anemia in anti-red blood cell autoantibody transgenic mice. International Immunology. 11: 995-1000. PMID 10360974 DOI: 10.1093/Intimm/11.6.995  0.583
1999 Shinkura R, Kitada K, Matsuda F, Tashiro K, Ikuta K, Suzuki M, Kogishi K, Serikawa T, Honjo T. Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase. Nature Genetics. 22: 74-7. PMID 10319865 DOI: 10.1038/8780  0.586
1999 Lee J, Haruna T, Ishimoto A, Honjo T, Yanagawa S. Intracisternal type A particle-mediated activation of the Notch4/int3 gene in a mouse mammary tumor: generation of truncated Notch4/int3 mRNAs by retroviral splicing events. Journal of Virology. 73: 5166-5171. PMID 10233982 DOI: 10.1128/Jvi.73.6.5166-5171.1999  0.312
1999 Kuroda K, Tani S, Tamura K, Minoguchi S, Kurooka H, Honjo T. Delta-induced Notch Signaling Mediated by RBP-J Inhibits MyoD Expression and Myogenesis Journal of Biological Chemistry. 274: 7238-7244. PMID 10066785 DOI: 10.1074/Jbc.274.11.7238  0.319
1999 Tani S, Taniwaki M, Taniguchi Y, Minoguchi S, Kuroda K, Han H, Aoki T, Miyatake S, Hashimoto N, Honjo T. Chromosomal mapping of two RBP-J-related genes: Kyo-T and RBP-L. Journal of Human Genetics. 44: 73-5. PMID 9929984 DOI: 10.1007/S100380050112  0.301
1999 Kinoshita K, Tashiro J, Tomita S, Lee CG, Honjo T. Target specificity of immunoglobulin class switch recombination is not determined by nucleotide sequences of S regions. Immunity. 9: 849-58. PMID 9881975 DOI: 10.1016/S1074-7613(00)80650-0  0.341
1999 Hoshiyama D, Suga H, Iwabe N, Koyanagi M, Nikoh N, Kuma K, Matsuda F, Honjo T, Miyata T. Sponge Pax cDNA related to Pax-2/5/8 and ancient gene duplications in the Pax family. Journal of Molecular Evolution. 47: 640-8. PMID 9847404 DOI: 10.1007/Pl00006421  0.324
1999 Matsuda F, Ishii K, Bourvagnet P, Kuma Ki, Hayashida H, Miyata T, Honjo T. The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus. The Journal of Experimental Medicine. 188: 2151-62. PMID 9841928 DOI: 10.1084/Jem.188.11.2151  0.333
1998 Kurooka H, Kuroda K, Honjo T. Roles of the ankyrin repeats and C-terminal region of the mouse notch1 intracellular region. Nucleic Acids Research. 26: 5448-5455. PMID 9826771 DOI: 10.1093/Nar/26.23.5448  0.323
1998 Nishimura H, Minato N, Nakano T, Honjo T. Immunological studies on PD-1 deficient mice: implication of PD-1 as a negative regulator for B cell responses. International Immunology. 10: 1563-1572. PMID 9796923 DOI: 10.1093/Intimm/10.10.1563  0.312
1998 Nisitani S, Sakiyama T, Honjo T. Involvement of IL-10 in induction of autoimmune hemolytic anemia in anti-erythrocyte Ig transgenic mice. International Immunology. 10: 1039-1047. PMID 9723689 DOI: 10.1093/Intimm/10.8.1039  0.347
1998 Watanabe N, Nomura T, Takai T, Chiba T, Honjo T, Tsubata T. Antigen Receptor Cross-Linking By Anti-Immunoglobulin Antibodies Coupled To Cell Surface Membrane Induces Rapid Apoptosis Of Normal Spleen B Cells Scandinavian Journal of Immunology. 47: 541-547. PMID 9652821 DOI: 10.1046/J.1365-3083.1998.00346.X  0.307
1998 Sakai T, Taniguchi Y, Tamura K, Minoguchi S, Fukuhara T, Strobl LJ, Zimber-Strobl U, Bornkamm GW, Honjo T. Functional replacement of the intracellular region of the Notch1 receptor by Epstein-Barr virus nuclear antigen 2. Journal of Virology. 72: 6034-9. PMID 9621066 DOI: 10.1128/Jvi.72.7.6034-6039.1998  0.337
1998 Lee CG, Kondo S, Honjo T. Frequent but biased class switch recombination in the S mu flanking regions. Current Biology : Cb. 8: 227-30. PMID 9501985 DOI: 10.1016/S0960-9822(98)70087-9  0.334
1998 Sugai M, Kondo S, Shimizu A, Honjo T. Isolation of differentially expressed genes upon immunoglobulin class switching by a subtractive hybridization method using uracil DNA glycosylase. Nucleic Acids Research. 26: 911-8. PMID 9461447 DOI: 10.1093/Nar/26.4.911  0.333
1998 Taniguchi Y, Furukawa T, Tun T, Han H, Honjo T. LIM protein KyoT2 negatively regulates transcription by association with the RBP-J DNA-binding protein. Molecular and Cellular Biology. 18: 644-54. PMID 9418910 DOI: 10.1128/Mcb.18.1.644  0.331
1997 Murakami M, Honjo T. Transgenic mouse models for B-cell dominant autoimmune diseases. Current Opinion in Immunology. 9: 846-850. PMID 9492988 DOI: 10.1016/S0952-7915(97)80188-4  0.343
1997 Bona CA, Murai C, Casares S, Kasturi K, Nishimura H, Honjo T, Matsuda F. Structure of the Mutant Fibrillin-1 Gene in the Tight Skin (TSK) Mouse Dna Research. 4: 267-271. PMID 9405934 DOI: 10.1093/Dnares/4.4.267  0.326
1997 Aoki T, Koike T, Nakano T, Shibahara K, Nishimura H, Kikuchi H, Honjo T. Rat TAFII31 gene is induced upon programmed cell death in differentiated PC12 cells deprived of NGF. Biochemical and Biophysical Research Communications. 234: 230-4. PMID 9168994 DOI: 10.1006/Bbrc.1997.6610  0.334
1997 Kurooka H, Kato K, Minoguchi S, Takahashi Y, Ikeda J, Habu S, Osawa N, Buchberg AM, Moriwaki K, Shisa H, Honjo T. Cloning and characterization of the nucleoredoxin gene that encodes a novel nuclear protein related to thioredoxin. Genomics. 39: 331-9. PMID 9119370 DOI: 10.1006/Geno.1996.4493  0.328
1997 Minoguchi S, Taniguchi Y, Kato H, Okazaki T, Strobl LJ, Zimber-Strobl U, Bornkamm GW, Honjo T. RBP-L, a transcription factor related to RBP-Jkappa. Molecular and Cellular Biology. 17: 2679-87. PMID 9111338 DOI: 10.1128/Mcb.17.5.2679  0.306
1997 Chen NN, Kerr D, Chang CF, Honjo T, Khalili K. Evidence for regulation of transcription and replication of the human neurotropic virus JCV genome by the human Sμbp-2 protein in glial cells Gene. 185: 55-62. PMID 9034313 DOI: 10.1016/S0378-1119(96)00630-0  0.358
1997 Murakami M, Nakajima K, Yamazaki K, Muraguchi T, Serikawa T, Honjo T. Effects of breeding environments on generation and activation of autoreactive B-1 cells in anti-red blood cell autoantibody transgenic mice Journal of Experimental Medicine. 185: 791-794. PMID 9034157 DOI: 10.1084/Jem.185.4.791  0.319
1997 Shirozu M, Tada H, Tashiro K, Nakamura T, Lopez ND, Nazarea M, Hamada T, Sato T, Nakano T, Honjo T. Characterization of novel secreted and membrane proteins isolated by the signal sequence trap method. Genomics. 37: 273-80. PMID 8938438 DOI: 10.1006/Geno.1996.0560  0.325
1997 Tamura K, Taniguchi Y, Minoguchi S, Sakai T, Tun T, Furukawa T, Honjo T. Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H). Current Biology : Cb. 5: 1416-23. PMID 8749394 DOI: 10.1016/S0960-9822(95)00279-X  0.351
1997 Kurooka H, Segre JA, Hirano Y, Nemhauser JL, Nishimura H, Yoneda K, Lander ES, Honjo T. Rescue of the hairless phenotype in nude mice by transgenic insertion of the wild-type Hfh11 genomic locus. International Immunology. 8: 961-6. PMID 8671685 DOI: 10.1093/Intimm/8.6.961  0.335
1996 Tsubata R, Tsubata T, Hiai H, Shinkura R, Matsumura R, Sumida T, Miyawaki S, Ishida H, Kumagai S, Nakao K, Honjo T. Autoimmune disease of exocrine organs in immunodeficient alymphoplasia mice: a spontaneous model for Sjögren's syndrome. European Journal of Immunology. 26: 2742-2748. PMID 8921964 DOI: 10.1002/Eji.1830261129  0.301
1996 Hamada T, Tashiro K, Tada H, Inazawa J, Shirozu M, Shibahara K, Nakamura T, Martina N, Nakano T, Honjo T. Isolation and characterization of a novel secretory protein, stromal cell-derived factor-2 (SDF-2) using the signal sequence trap method. Gene. 176: 211-4. PMID 8918255 DOI: 10.1016/0378-1119(96)00251-X  0.316
1996 Han H, Nomura T, Honjo T, Tsubata T. Differential modulation of cyclin‐dependent kinase inhibitor p27Kip1 by negative signaling via the antigen receptor of B cells and positive signaling via CD40 European Journal of Immunology. 26: 2425-2432. PMID 8898956 DOI: 10.1002/Eji.1830261024  0.31
1996 Murakami M, Honjo T. Anti-red blood cell autoantibody transgenic mice: murine model of autoimmune hemolytic anemia. Seminars in Immunology. 8: 3-9. PMID 8850293 DOI: 10.1006/Smim.1996.0002  0.338
1996 Shinkura R, Matsuda F, Sakiyama T, Tsubata T, Hiai H, Paumen M, Miyawaki S, Honjo T. Defects of somatic hypermutation and class switching in alymphoplasia (aly) mutant mice International Immunology. 8: 1067-1075. PMID 8757952 DOI: 10.1093/Intimm/8.7.1067  0.316
1996 Agata Y, Kawasaki A, Nishimura H, Ishida Y, Tsubata T, Yagita H, Honjo T. Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes International Immunology. 8: 765-772. PMID 8671665 DOI: 10.1093/Intimm/8.5.765  0.324
1996 Nakamura M, Kondo S, Sugai M, Nazarea M, Imamura S, Honjo T. High frequency class switching of an IgM+ B lymphoma clone CH12F3 to IgA+ cells. International Immunology. 8: 193-201. PMID 8671604 DOI: 10.1093/Intimm/8.2.193  0.336
1996 Shirozu M, Nakano T, Inazawa J, Tashiro K, Tada H, Shinohara T, Honjo T. Structure and chromosomal localization of the human stromal cell-derived factor 1 (SDF1) gene. Genomics. 28: 495-500. PMID 7490086 DOI: 10.1006/Geno.1995.1180  0.319
1995 Sakai T, Furukawa T, Iwanari H, Oka C, Nakano T, Kawaichi M, Honjo T. Loss of immunostaining of the RBP-J kappa transcription factor upon F9 cell differentiation induced by retinoic acid. Journal of Biochemistry. 118: 621-628. PMID 8690727 DOI: 10.1093/Oxfordjournals.Jbchem.A124955  0.303
1995 Shibahara K, Asano M, Ishida Y, Aoki T, Koike T, Honjo T. Isolation of a novel mouse gene MA-3 that is induced upon programmed cell death. Gene. 166: 297-301. PMID 8543179 DOI: 10.1016/0378-1119(95)00607-9  0.355
1995 Murakami M, Yoshioka H, Shirai T, Tsubata T, Honjo T. Prevention of autoimmune symptoms in autoimmune-prone mice by elimination of B-1 cells International Immunology. 7: 877-882. PMID 7547714 DOI: 10.1093/Intimm/7.5.877  0.335
1995 Furukawa T, Kobayakawa Y, Tamura K, Kimura KI, Kawaichi M, Tanimura T, Honjo T. Suppressor of Hairless, the Drosophila homologue of RBP-Jχ, transactivates the neurogenic gene E(spl)m8 Japanese Journal of Genetics. 70: 505-524. PMID 7546844 DOI: 10.1266/Ggs.70.505  0.304
1995 Tsubata T, Murakami M, Nisitani S, Honjo T. Molecular mechanisms for B lymphocyte selection: induction and regulation of antigen-receptor-mediated apoptosis of mature B cells in normal mice and their defect in autoimmunity-prone mice Philosophical Transactions of the Royal Society B. 345: 297-301. PMID 7531346 DOI: 10.1098/Rstb.1994.0109  0.346
1995 Murakami M, Honjo T. Involvement of B-1 cells in mucosal immunity and autoimmunity Immunology Today. 16: 534-539. PMID 7495491 DOI: 10.1016/0167-5699(95)80047-6  0.306
1995 Nisitani S, Tsubata T, Murakami M, Honjo T. Administration of interleukin ‐5 or ‐10 activates peritoneal B‐1 cells and induces autoimmune hemolytic anemia in anti‐erythrocyte autoantibody‐transgenic mice European Journal of Immunology. 25: 3047-3052. PMID 7489742 DOI: 10.1002/Eji.1830251110  0.324
1995 Oka C, Nakano T, Wakeham A, Pompa JLdl, Mori C, Sakai T, Okazaki S, Kawaichi M, Shiota K, Mak TW, Honjo T. Disruption of the mouse RBP-J kappa gene results in early embryonic death Development. 121: 3291-3301. DOI: 10.11501/3108339  0.357
1994 Tun T, Hamaguchi Y, Matsunami N, Furukawa T, Honjo T, Kawaichi M. Recognition sequence of a highly conserved DNA binding protein RBP-J kappa. Nucleic Acids Research. 22: 965-71. PMID 8152928 DOI: 10.1093/Nar/22.6.965  0.31
1994 Nisitani S, Tsubata T, Honjo T. Lineage marker-negative lymphocyte precursors derived from embryonic stem cells in vitro differentiate into mature lymphocytes in vivo. International Immunology. 6: 909-916. PMID 8086378 DOI: 10.1093/Intimm/6.6.909  0.382
1994 Nakano T, Kodama H, Honjo T. Generation of Lymphohematopoietic Cells from Embryonic Stem Cells in Culture Science. 265: 1098-1101. PMID 8066449 DOI: 10.1126/Science.8066449  0.306
1994 Murakami M, Tsubata T, Shinkura R, Nisitani S, Okamoto M, Yoshioka H, Usui T, Miyawaki S, Honjo T. Oral administration of lipopolysaccharides activates B-1 cells in the peritoneal cavity and lamina propria of the gut and induces autoimmune symptoms in an autoantibody transgenic mouse Journal of Experimental Medicine. 180: 111-121. PMID 8006578 DOI: 10.1084/Jem.180.1.111  0.317
1994 Tsubata T, Murakami M, Honjo T. Antigen-receptor cross-linking induces peritoneal B-cell apoptosis in normal but not autoimmunity-prone mice Current Biology. 4: 8-17. PMID 7922322 DOI: 10.1016/S0960-9822(00)00003-8  0.349
1994 Furukawa T, Kimura K, Kobayakawa Y, Tamura K, Kawaichi M, Tanimura T, Honjo T. Genetic characterization of Drosophila RBP-Jκ (Suppressor of Hairless) as a neurogenic gene in adult PNS development Japanese Journal of Genetics. 69: 701-711. PMID 7857674 DOI: 10.1266/Ggs.69.701  0.358
1994 Zimber-Strobl U, Strobl L, Meitinger C, Hinrichs R, Sakai T, Furukawa T, Honjo T, Bornkamm G. Epstein-Barr virus nuclear antigen 2 exerts its transactivating function through interaction with recombination signal binding protein RBP-J kappa, the homologue of Drosophila Suppressor of Hairless. The Embo Journal. 13: 4973-4982. DOI: 10.1002/J.1460-2075.1994.Tb06824.X  0.315
1993 Mizuta TR, Fukita Y, Miyoshi T, Shimizu A, Honjo T. Isolation of cDNA encoding a binding protein specific to 5'-phosphorylated single-stranded DNA with G-rich sequences. Nucleic Acids Research. 21: 1761-6. PMID 8493094 DOI: 10.1093/Nar/21.8.1761  0.335
1993 Matsuda F, Shin EK, Nagaoka H, Matsumura R, Haino M, Fukita Y, Taka-Ishi S, Imai T, Riley JH, Anand R, Soeda E, Honjo T. Structure and physical map of 64 variable segments in the 3′ 0.8–megabase region of the human immunoglobulin heavy–chain locus Nature Genetics. 3: 88-94. PMID 8490662 DOI: 10.1038/Ng0193-88  0.313
1993 Amakawa R, Jing W, Ozawa K, Matsunami N, Hamaguchi Y, Matsuda F, Kawaichi M, Honjo T. Human Jk recombination signal binding protein gene (IGKJRB): comparison with its mouse homologue. Genomics. 17: 306-15. PMID 8406481 DOI: 10.1006/Geno.1993.1326  0.349
1993 Nisitani S, Tsubata T, Murakami M, Okamoto M, Honjo T. The bcl-2 gene product inhibits clonal deletion of self-reactive B lymphocytes in the periphery but not in the bone marrow. Journal of Experimental Medicine. 178: 1247-1254. PMID 8376932 DOI: 10.1084/Jem.178.4.1247  0.33
1993 Haire RN, Buell RD, Litman RT, Ohta Y, Fu SM, Honjo T, Matsuda F, de la Morena M, Carro J, Good RA. Diversification, not use, of the immunoglobulin VH gene repertoire is restricted in DiGeorge syndrome. The Journal of Experimental Medicine. 178: 825-34. PMID 8350056 DOI: 10.1084/Jem.178.3.825  0.376
1993 Tashiro K, Tada H, Heilker R, Shirozu M, Nakano T, Honjo T. Signal sequence trap: a cloning strategy for secreted proteins and type I membrane proteins. Science (New York, N.Y.). 261: 600-3. PMID 8342023 DOI: 10.1126/Science.8342023  0.338
1993 Shimada MO, Yamada Y, Nakakuki Y, Okamoto K, Fukumoto M, Honjo T, Hiai H. SL/KH strain of mice: a model of spontaneous pre-B-lymphomas. Leukemia Research. 17: 573-8. PMID 8326739 DOI: 10.1016/0145-2126(93)90087-2  0.323
1993 Saito Y, Nazarea M, Honjo T. Pseudo-high-affinity IL-2 receptor and growth signal transduction in lymphocytes. International Immunology. 5: 1211-1217. PMID 8268128 DOI: 10.1093/Intimm/5.10.1211  0.308
1993 Shimizu A, Honjo T. Synthesis and regulation of trans-mRNA encoding the immunoglobulin epsilon heavy chain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 7: 149-54. PMID 7916698 DOI: 10.1096/Fasebj.7.1.7916698  0.31
1993 Tsubata T, Wu J, Honjo T. B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T-cell signal through CD40. Nature. 364: 645-8. PMID 7688865 DOI: 10.1038/364645A0  0.342
1992 Okamoto M, Murakami M, Shimizu A, Ozaki S, Tsubata T, Kumagai S, Honjo T. A transgenic model of autoimmune hemolytic anemia. The Journal of Experimental Medicine. 175: 71-9. PMID 1730928 DOI: 10.1084/Jem.175.1.71  0.321
1992 Furukawa T, Maruyama S, Kawaichi M, Honjo T. The Drosophila homolog of the immunoglobulin recombination signal-binding protein regulates peripheral nervous system development. Cell. 69: 1191-7. PMID 1617729 DOI: 10.1016/0092-8674(92)90640-X  0.354
1992 Murakami M, Tsubata T, Okamoto M, Shimizu A, Kumagai S, Imura H, Honjo T. Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice Nature. 357: 77-80. PMID 1574128 DOI: 10.1038/357077A0  0.305
1992 Aoki T, Tashiro K, Miyatake S, Kinashi T, Nakano T, Oda Y, Kikuchi H, Honjo T. Expression of murine interleukin 7 in a murine glioma cell line results in reduced tumorigenicity in vivo. Proceedings of the National Academy of Sciences of the United States of America. 89: 3850-3854. PMID 1570303 DOI: 10.1073/Pnas.89.9.3850  0.33
1992 Hamaguchi Y, Yamamoto Y, Iwanari H, Maruyama S, Furukawa T, Matsunami N, Honjo T. Biochemical and immunological characterization of the DNA binding protein (RBP-J kappa) to mouse J kappa recombination signal sequence. Journal of Biochemistry. 112: 314-320. PMID 1429518 DOI: 10.1093/Oxfordjournals.Jbchem.A123898  0.304
1992 Takahashi Y, Shimizu A, Sakai T, Endo Y, Osawa N, Shisa H, Honjo T. Mapping of the nu gene using congenic nude strains and in situ hybridization. The Journal of Experimental Medicine. 175: 873-6. PMID 1346798 DOI: 10.1084/Jem.175.3.873  0.301
1992 Ishida Y, Agata Y, Shibahara K, Honjo T. Induced expression of PD‐1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. The Embo Journal. 11: 3887-3895. DOI: 10.1002/J.1460-2075.1992.Tb05481.X  0.356
1991 Kinoshita K, Shimizu A, Honjo T. The membrane exons of the pseudo-gamma-chain gene of the human immunoglobulin are apparently functional and highly homologous to those of the gamma 1 gene. Immunology Letters. 27: 151-5. PMID 2026457 DOI: 10.1016/0165-2478(91)90143-X  0.359
1991 Hamaguchi Y, Mastunami N, Yamamoto Y, Kuze K, Kangawa K, Matsuo H, Kawaichi M, Honjo T. Cloning and characterization of a protein binding to the J kappa recombination signal sequence of immunoglobulin genes. Advances in Experimental Medicine and Biology. 292: 177-86. PMID 1950768 DOI: 10.1007/978-1-4684-5943-2_20  0.333
1991 Kuze K, Shimizu A, Honjo T. Characterization of the enhancer region for germline transcription of the gamma 3 constant region gene of human immunoglobulin. International Immunology. 3: 647-55. PMID 1911538 DOI: 10.1093/Intimm/3.7.647  0.372
1991 Tashiro K, Kinashi T, Anderson SJ, Lee KH, Tohyama K, Ogawa M, Takahashi M, Kawaichi M, Honjo T. Germline transcripts of the immunoglobulin heavy-chain and T cell receptor genes in a murine hematopoietic stem cell line LyD9 and its derivative cell lines. Immunology Letters. 28: 147-54. PMID 1909302 DOI: 10.1016/0165-2478(91)90113-O  0.378
1991 Shimizu A, Nussenzweig MC, Han H, Sanchez M, Honjo T. Trans-splicing as a possible molecular mechanism for the multiple isotype expression of the immunoglobulin gene. Journal of Experimental Medicine. 173: 1385-1393. PMID 1903429 DOI: 10.1084/Jem.173.6.1385  0.378
1991 Han H, Okamoto M, Honjo T, Shimizu A. Regulated expression of immunoglobulin trans-mRNA consisting of the variable region of a transgenic μ chain and constant regions of endogenous isotypes International Immunology. 3: 1197-1206. PMID 1777416 DOI: 10.1093/Intimm/3.12.1197  0.335
1991 Kinashi T, Lee KH, Ogawa M, Tohyama K, Tashiro K, Fukunaga R, Nagata S, Honjo T. Premature expression of the macrophage colony-stimulating factor receptor on a multipotential stem cell line does not alter differentiation lineages controlled by stromal cells used for coculture. The Journal of Experimental Medicine. 173: 1267-79. PMID 1708812 DOI: 10.1084/Jem.173.5.1267  0.308
1991 Lee KH, Kinashi T, Tohyama K, Tashiro K, Funato N, Hama K, Honjo T. Different stromal cell lines support lineage-selective differentiation of the multipotential bone marrow stem cell clone LyD9. Journal of Experimental Medicine. 173: 1257-1266. PMID 1708811 DOI: 10.1084/Jem.173.5.1257  0.305
1991 Tashiro K, Nakano T, Honjo T, Aoki T, Miyatake S, Oda Y, Kikuchi H. Expression of the RAG-2 gene in murine central nervous system tumor cell lines. Biochemical and Biophysical Research Communications. 181: 151-158. PMID 1683534 DOI: 10.1016/S0006-291X(05)81394-4  0.348
1991 Iwamoto K, Shintani Y, Sasada R, Honjo T, Kitano K. Improvement in the antibody productivity of human-human hybridomas by transfection with Tac gene. Cytotechnology. 4: 29-37. PMID 1366720 DOI: 10.1007/Bf00148808  0.335
1991 Amakawa R, Fukuhara S, Ohno H, Matsuyama F, Kato I, Tanabe S, Sideras P, Mizuta T, Honjo T, Okuma M. Genomic organization of IgH gene compared with the expression of Bcl-2 gene in t(14;18)-positive lymphoma Blood. 77: 1970-1976. DOI: 10.1182/Blood.V77.9.1970.Bloodjournal7791970  0.371
1991 Morita M, Saito H, Honjo T, Saito Y, Tsuruta S, Kim K, Tanaka M, Mori KJ, Mayumi M, Mikawa H. Differentiation of a human eosinophilic leukemia cell line (EoL-1) by a human T-cell leukemia cell line (HIL-3)-derived factor. Blood. 77: 1766-1775. DOI: 10.1182/Blood.V77.8.1766.Bloodjournal7781766  0.308
1991 Era T, Ogawa M, Nishikawa SI, Okamoto M, Honjo T, Akagi K, Miyazaki JI, Yamamura KI. Differentiation of growth signal requirement of B lymphocyte precursor is directed by expression of immunoglobulin. The Embo Journal. 10: 337-342. DOI: 10.1002/J.1460-2075.1991.Tb07954.X  0.328
1991 Shin EK, Matsuda F, Nagaoka H, Fukita Y, Imai T, Yokoyama K, Soeda E, Honjo T. Physical map of the 3' region of the human immunoglobulin heavy chain locus: clustering of autoantibody-related variable segments in one haplotype. The Embo Journal. 10: 3641-3645. DOI: 10.1002/J.1460-2075.1991.Tb04930.X  0.319
1990 Mizuta TR, Tanabe T, Nakakubo H, Noma T, Honjo T. Molecular cloning and structure of the mouse interleukin-5 gene. Growth Factors (Chur, Switzerland). 1: 51-7. PMID 3078564 DOI: 10.3109/08977198809000246  0.348
1990 Matsunami N, Hamaguchi Y, Yamamoto Y, Kuze K, Kangawa K, Matsuo H, Kawaichi M, Honjo T. A protein binding to the J kappa recombination sequence of immunoglobulin genes contains a sequence related to the integrase motif. Nature. 342: 934-7. PMID 2556644 DOI: 10.1038/342934A0  0.317
1990 Iwasato T, Shimizu A, Honjo T, Yamagishi H. Circular DNA is excised by immunoglobulin class switch recombination. Cell. 62: 143-9. PMID 2364432 DOI: 10.1016/0092-8674(90)90248-D  0.327
1990 Okamoto M, Honjo T. Nucleotide sequences of the gene/cDNA coding for anti-murine erythrocyte autoantibody produced by a hybridoma from NZB mouse. Nucleic Acids Research. 18: 1895. PMID 2336368 DOI: 10.1093/Nar/18.7.1895  0.318
1990 Ikeda T, Kita K, Miwa H, Kawakami K, Anazawa H, Ohno T, Nosaka T, Hatanaka M, Honjo T, Shirakawa S. Genetic heterogeneity in blast crisis of chronic myelocytic leukemia. Leukemia Research. 14: 195-201. PMID 2156114 DOI: 10.1016/0145-2126(90)90049-F  0.314
1990 Ohno H, Furukawa T, Fukuhara S, Zong SQ, Kamesaki H, Shows TB, Le Beau MM, McKeithan TW, Kawakami T, Honjo T. Molecular analysis of a chromosomal translocation, t(9;14)(p13;q32), in a diffuse large-cell lymphoma cell line expressing the Ki-1 antigen. Proceedings of the National Academy of Sciences of the United States of America. 87: 628-32. PMID 2153959 DOI: 10.1073/Pnas.87.2.628  0.352
1990 Nakatani T, Horigome K, Nomura N, Kondo T, Ohtsuka H, Noguchi H, Honjo T. Deletion of human JK segments by site-specific recombination recognizing the conserved nonamer and heptamer sequences. Nucleic Acids Research. 18: 5529-32. PMID 2120678 DOI: 10.1093/Nar/18.18.5529  0.349
1990 Ikeda T, Kita K, Kawakami K, Ohno T, Seki S, Nasu K, Ueda T, Honjo T, Shirakawa S. Oligoclonal Immunoglobulin Gene Rearrangements in Philadelphia Chromosome‐positive Common Acute Lymphoblastic Leukemia Japanese Journal of Cancer Research. 81: 340-344. PMID 2114388 DOI: 10.1111/J.1349-7006.1990.Tb02573.X  0.311
1990 Kinashi T, Tashiro K, Lee KH, Inaba K, Toyama K, Palacios R, Honjo T. Growth factors involved in lymphocyte differentiation. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 327: 117-25. PMID 1969653 DOI: 10.1098/Rstb.1990.0048  0.371
1990 Tohyama K, Lee KH, Tashiro K, Kinashi T, Honjo T. Establishment of an interleukin-5-dependent subclone from an interleukin-3-dependent murine hemopoietic progenitor cell line, LyD9, and its malignant transformation by autocrine secretion of interleukin-5. The Embo Journal. 9: 1823-1830. DOI: 10.1002/J.1460-2075.1990.Tb08307.X  0.342
1990 Matsuda F, Shin EK, Hirabayashi Y, Nagaoka H, Yoshida MC, Zong SQ, Honjo T. Organization of variable region segments of the human immunoglobulin heavy chain: duplication of the D5 cluster within the locus and interchromosomal translocation of variable region segments. The Embo Journal. 9: 2501-2506. DOI: 10.1002/J.1460-2075.1990.Tb07429.X  0.306
1989 Mita S, Tominaga A, Hitoshi Y, Sakamoto K, Honjo T, Akagi M, Kikuchi Y, Yamaguchi N, Takatsu K. Characterization of high-affinity receptors for interleukin 5 on interleukin 5-dependent cell lines. Proceedings of the National Academy of Sciences of the United States of America. 86: 2311-2315. PMID 2784567 DOI: 10.1073/Pnas.86.7.2311  0.316
1989 Shimizu A, Kinashi T, Nussenzweig MC, Mizuta TR, Leder P, Honjo T. Molecular mechanism for immunoglobulin double-isotype expression. Cold Spring Harbor Symposia On Quantitative Biology. 54: 175-81. PMID 2639752 DOI: 10.1101/Sqb.1989.054.01.022  0.47
1989 Ishida Y, Nishi M, Taguchi O, Inaba K, Hattori M, Minato N, Kawaichi M, Honjo T. Expansion of natural killer cells but not T cells in human interleukin 2/interleukin 2 receptor (Tac) transgenic mice. Journal of Experimental Medicine. 170: 1103-1115. PMID 2571665 DOI: 10.1084/Jem.170.4.1103  0.342
1989 Yamamoto M, Takai S, Miki T, Motomura K, Okazaki M, Nishisho I, Tateishi H, Miyauchi A, Honjo T, Pakstis AJ, Mori T. Close linkage of MEN2A with RBP3 locus in Japanese kindreds. Human Genetics. 82: 287-288. PMID 2567278 DOI: 10.1007/Bf00291173  0.308
1989 Sideras P, Mizuta Tr, Kanamorl H, Suzuki N, Okamoto M, Kuze K, Ohno H, Dol S, Fukuhara S, Hassan MS, Hammarstöm L, Edward S, Shimzu A, Honjo T. Production of sterile transcripts of Cγ genes in an IgM-producing human neoplastic B cell line that switches to IgG-producing cells International Immunology. 1: 631-642. PMID 2518730 DOI: 10.1093/Intimm/1.6.631  0.394
1989 Shimizu A, Nussenzweig MC, Mizuta TR, Leder P, Honjo T. Immunoglobulin double-isotype expression by trans-mRNA in a human immunoglobulin transgenic mouse. Proceedings of the National Academy of Sciences of the United States of America. 86: 8020-3. PMID 2510157 DOI: 10.1073/Pnas.86.20.8020  0.561
1989 Ishida Y, Nishi M, Taguchl O, Inaba K, Minato N, Kawaichi M, Honjo T. Effects of the deregulated expression of human interleukin-2 in transgenic mice International Immunology. 1: 113-120. PMID 2487682 DOI: 10.1093/Intimm/1.2.113  0.311
1989 Kinashi T, Tashiro K, Inaba K, Takeda T, Palacios R, Honjo T. An interleukin-4-dependent precursor clone is an intermediate of the differentiation pathway from an interleukin-3-dependent precursor clone into myeloid cells as well as B lymphocytes. International Immunology. 1: 11-9. PMID 2487673 DOI: 10.1093/Intimm/1.1.11  0.331
1989 Noma T, Nakakubo H, Hama K, Honjo T. Multiple effects of human recombinant interleukin 4 on human myeloid monocyte cell lines Immunology Letters. 21: 323-328. PMID 2475440 DOI: 10.1016/0165-2478(89)90027-8  0.304
1989 Noma T, Nakakubo H, Sugita M, Kumagai S, Maeda M, Shimizu A, Honjo T. Expression of different combinations of interleukins by human T cell leukemic cell lines that are clonally related. Journal of Experimental Medicine. 169: 1853-1858. PMID 2469771 DOI: 10.1084/Jem.169.5.1853  0.32
1989 Kanamori H, Suzuki N, Ishida N, Honjo T. Transcriptional regulation alone does not explain the constitutive expression of the interleukin 2 receptor (Tac/L-chain) in HTLV-1 infected cells. Immunology Letters. 20: 293-298. PMID 2469652 DOI: 10.1016/0165-2478(89)90037-0  0.343
1988 Fujita J, Nakayama H, Onoue H, Kanakura Y, Nakano T, Asai H, Takeda S‐, Honjo T, Kitamura Y. Fibroblast-dependent growth of mouse mast cells in vitro: duplication of mast cell depletion in mutant mice of W/Wv genotype. Journal of Cellular Physiology. 134: 78-84. PMID 3275680 DOI: 10.1002/Jcp.1041340109  0.334
1988 Kinashi T, Inaba K, Tsubata T, Tashiro K, Palacios R, Honjo T. Differentiation of an interleukin 3-dependent precursor B-cell clone into immunoglobulin-producing cells in vitro. Proceedings of the National Academy of Sciences of the United States of America. 85: 4473-7. PMID 3260035 DOI: 10.1073/Pnas.85.12.4473  0.377
1988 Tominaga N, Katagiri S, Hamaguchi Y, Nishiura T, Kanakura Y, Kanayama Y, Nagao K, Kakiuchi Y, Nishida K, Abe T, Honjo T, Yonezawa T, Tarui S. Plasma cell leukaemia of non‐producer type with missing light chain gene rearrangement British Journal of Haematology. 69: 213-218. PMID 3134042 DOI: 10.1111/J.1365-2141.1988.Tb07624.X  0.335
1988 Ueda S, Matsuda F, Honjo T. Multiple recombinational events in primate immunoglobulin epsilon and alpha genes suggest closer relationship of humans to chimpanzees than to gorillas Journal of Molecular Evolution. 27: 77-83. PMID 3133489 DOI: 10.1007/Bf02099732  0.305
1988 Miwa H, Nosaka T, Kita K, Ohno T, Matsuoka N, Shirakawa S, Arita Y, Doi S, Nishikori M, Honjo T, Hatanaka M. Immunogenotypes of Lymphoid Malignancies; the Rearrangement of T Cell Receptor β Chain Gene Can Occur before the γ Chain Gene Rearrangement Japanese Journal of Cancer Research. 79: 484-490. PMID 3133337 DOI: 10.1111/J.1349-7006.1988.Tb01617.X  0.365
1988 Takeda SI, Hamaguchi Y, Zong SQ, Kuze K, Honjo T, Ishimoto M, Nakano T, Kitamura Y. Introduction and Expression of the Interleukin 2 Receptor (Tac) Gene in Hematopoietic Stem Cells with Retrovirus Vectors Growth Factors Journal. 1: 59-66. PMID 3078565 DOI: 10.3109/08977198809000247  0.354
1988 Kinashi T, Inba K, Tsubata T, Tashiro K, Palacios R, Honjo T. Differentiation of a Precursor Cell with the Germline Context of Immunoglobulin Gene into Immunoglobulin‐Producing Cells in Vitro Annals of the New York Academy of Sciences. 546: 1-8. PMID 3073688 DOI: 10.1111/J.1749-6632.1988.Tb21613.X  0.35
1988 Sato T, Matsuda F, Lee KH, Shin EK, Honjo T. Physical linkage of a variable region segment and the joining region segment of the human immunoglobulin heavy chain locus. Biochemical and Biophysical Research Communications. 154: 265-71. PMID 2840067 DOI: 10.1016/0006-291X(88)90679-1  0.322
1988 Nosaka T, Ohno H, Doi S, Fukuhara S, Miwa H, Kita K, Shirakawa S, Honjo T, Hatanaka M. Phenotypic conversion of T lymphoblastic lymphoma to acute biphenotypic leukemia composed of lymphoblasts and myeloblasts. Molecular genetic evidence of the same clonal origin. The Journal of Clinical Investigation. 81: 1824-8. PMID 2838522 DOI: 10.1172/Jci113526  0.34
1988 Nishi M, Ishida Y, Honjo T. Expression of functional interleukin-2 receptors in human light chain/Tac transgenic mice. Nature. 331: 267-269. PMID 2827038 DOI: 10.1038/331267A0  0.328
1988 Yaoita Y, Takahashi M, Azuma C, Kanai Y, Honjo T. Biased expression of variable region gene families of the immunoglobulin heavy chain in autoimmune-prone mice. Journal of Biochemistry. 104: 337-343. PMID 2467902 DOI: 10.1093/Oxfordjournals.Jbchem.A122470  0.348
1987 Takatsu K, Kikuchi Y, Takahashi T, Honjo T, Matsumoto M, Harada N, Yamaguchi N, Tominaga A. Interleukin 5, a T-cell-derived B-cell differentiation factor also induces cytotoxic T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 84: 4234-4238. PMID 3495803 DOI: 10.1073/Pnas.84.12.4234  0.362
1987 Severinson E, Naito T, Tokumoto H, Fukushima D, Hirano A, Hama K, Honjo T. Interleukin 4 (IgG1 induction factor): a multifunctional lymphokine acting also on T cells. European Journal of Immunology. 17: 67-72. PMID 3493156 DOI: 10.1002/Eji.1830170112  0.328
1987 Harada N, Matsumoto M, Koyama N, Shimizu A, Honjo T, Tominaga A, Takatsu K. T cell replacing factor/interleukin 5 induces not only B-cell growth and differentiation, but also increased expression of interleukin 2 receptor on activated B-cells. Immunology Letters. 15: 205-215. PMID 3117678 DOI: 10.1016/0165-2478(87)90026-5  0.335
1987 Lee KH, Matsuda F, Kinashi T, Kodaira M, Honjo T. A novel family of variable region genes of the human immunoglobulin heavy chain. Journal of Molecular Biology. 195: 761-8. PMID 3116265 DOI: 10.1016/0022-2836(87)90482-7  0.304
1987 Kondo S, Kinoshita M, Shimizu A, Saito Y, Konishi M, Sabe H, Honjo T. Expression and functional characterization of artificial mutants of interleukin-2 receptor. Nature. 327: 64-67. PMID 3106825 DOI: 10.1038/327064A0  0.311
1987 Sakoyama Y, Hong KJ, Byun SM, Hisajima H, Ueda S, Yaoita Y, Hayashida H, Miyata T, Honjo T. Nucleotide sequences of immunoglobulin epsilon genes of chimpanzee and orangutan: DNA molecular clock and hominoid evolution. Proceedings of the National Academy of Sciences of the United States of America. 84: 1080-4. PMID 3103123 DOI: 10.1073/Pnas.84.4.1080  0.338
1987 Kodaira M, Kinashi T, Umemura I, Matsuda F, Noma T, Ono Y, Honjo T. Organization and evolution of variable region genes of the human immunoglobulin heavy chain. Journal of Molecular Biology. 190: 529-41. PMID 3097326 DOI: 10.1016/0022-2836(86)90239-1  0.322
1987 Otsu M, Katamine S, Uno M, Yamaki M, Ono Y, Klein G, Sasaki MS, Yaoita Y, Honjo T. Molecular characterization of novel reciprocal translocation t(6;14) in an Epstein-Barr virus-transformed B cell precursor. Molecular and Cellular Biology. 7: 708-17. PMID 3029565 DOI: 10.1128/Mcb.7.2.708  0.386
1987 Ikuta K, Takami M, Kim CW, Honjo T, Miyoshi T, Tagaya Y, Kawabe T, Yodoi J. Human lymphocyte Fc receptor for IgE: sequence homology of its cloned cDNA with animal lectins. Proceedings of the National Academy of Sciences of the United States of America. 84: 819-23. PMID 2949326 DOI: 10.1073/Pnas.84.3.819  0.567
1987 Noma T, Mizuta T, Rosén A, Hirano T, Kishimoto T, Honjo T. Enhancement of the interleukin 2 receptor expression on T cells by multiple B-lymphotropic lymphokines. Immunology Letters. 15: 249-253. PMID 2889667 DOI: 10.1016/0165-2478(87)90032-0  0.33
1987 Tagaya Y, Taniguchi Y, Naramura M, Okada M, Suzuki N, Kanamori H, Nikaido T, Honjo T, Yodoi J. Transcription of IL-2 receptor gene is stimulated by ATL-derived factor produced by HTLV-I(+) T cell lines Immunology Letters. 15: 221-228. PMID 2889666 DOI: 10.1016/0165-2478(87)90028-9  0.322
1987 Kinashi T, Godal T, Noma Y, Ling NR, Yaoita Y, Honjo T. Human neoplastic B cells express more than two isotypes of immunoglobulins without deletion of heavy-chain constant-region genes. Genes & Development. 1: 465-470. PMID 2824283 DOI: 10.1101/Gad.1.5.465  0.388
1987 Harada N, Takahashi T, Matsumoto M, Kinashi T, Ohara J, Kikuchi Y, Koyama N, Severinson E, Yaoita Y, Honjo T. Production of a monoclonal antibody useful in the molecular characterization of murine T-cell-replacing factor/B-cell growth factor II. Proceedings of the National Academy of Sciences of the United States of America. 84: 4581-5. PMID 2440025 DOI: 10.1073/Pnas.84.13.4581  0.335
1986 Ikuta K, Hattori M, Wake K, Kano S, Honjo T, Yodoi J, Minato N. Expression and rearrangement of the alpha, beta, and gamma chain genes of the T cell receptor in cloned murine large granular lymphocyte lines. No correlation with the cytotoxic spectrum. The Journal of Experimental Medicine. 164: 428-42. PMID 3723079 DOI: 10.1084/Jem.164.2.428  0.599
1986 Ikuta K, Ogura T, Shimizu A, Honjo T. A joining-diversity-joining complex generated by inversion mechanism and a variable-diversity complex in the beta-chain gene of the human T-cell receptor. Nucleic Acids Research. 14: 4899-909. PMID 3487774 DOI: 10.1093/Nar/14.12.4899  0.527
1986 Shimizu A, Kondo S, Sabe H, Ishida N, Honjo T. Structure and function of the interleukin 2 receptor: affinity conversion model. Immunological Reviews. 92: 103-120. PMID 3091479 DOI: 10.1111/J.1600-065X.1986.Tb01496.X  0.311
1986 Kondo S, Shimizu A, Maeda M, Tagaya Y, Yodoi J, Honjo T. Expression of functional human interleukin-2 receptor in mouse T cells by cDNA transfection Nature. 320: 75-77. PMID 3081815 DOI: 10.1038/320075A0  0.314
1986 Azuma C, Tanabe T, Konishi M, Kinashi T, Noma T, Matsuda F, Yaoita Y, Takatsu K, Hammarström L, Smith CIE, Severinson E, Honjo T. Cloning of cDNA for human T-cell replacing factor (interieukin-5) and comparison with the murine homologue Nucleic Acids Research. 14: 9149-9158. PMID 3024129 DOI: 10.1093/Nar/14.22.9149  0.371
1986 Kinashi T, Harada N, Severinson E, Tanabe T, Sideras P, Konishi M, Azuma C, Tominaga A, Bergstedt-Lindqvist S, Takahashi M, Matsuda F, Yaoita Y, Takatsu K, Honjo T. Cloning of complementary DNA encoding T-cell replacing factor and identity with B-cell growth factor II. Nature. 324: 70-73. PMID 3024009 DOI: 10.1038/324070A0  0.366
1986 Noma T, Nakamura T, Maeda M, Okada M, Taniguchi Y, Tagaya Y, Yaoita Y, Yodoi J, Honjo T. Interleukin 1α mRNA in virus-transformed T and B cells Biochemical and Biophysical Research Communications. 139: 353-360. PMID 3021130 DOI: 10.1016/S0006-291X(86)80121-8  0.328
1986 Matsunami N, Siomi H, Hatanaka M, Yaoita Y, Honjo T. Preferential transcription of HTLV-I LTR in cell-free extracts of human T cells producing HTLV-I viral proteins. Nucleic Acids Research. 14: 4779-86. PMID 3014437 DOI: 10.1093/Nar/14.12.4779  0.336
1986 Noma Y, Sideras P, Naito T, Bergstedt-Lindquist S, Azuma C, Severinson E, Tanabe T, Kinashi T, Matsuda F, Yaoita Y, Honjo T. Cloning of cDNA encoding the murine IgG1 induction factor by a novel strategy using SP6 promoter. Nature. 319: 640-646. PMID 3005865 DOI: 10.1038/319640A0  0.369
1986 Maeda M, Shimizu A, Ikuta K, Okamoto H, Kashihara M, Uchiyama T, Honjo T, Yodoi J. Origin of human T-lymphotrophic virus I-positive T cell lines in adult T cell leukemia. Analysis of T cell receptor gene rearrangement. The Journal of Experimental Medicine. 162: 2169-74. PMID 2866223 DOI: 10.1084/Jem.162.6.2169  0.598
1986 Kinashi T, Harada N, Severinson E, Tanabe T, Sideras P, Konishi M, Azuma C, Tominaga A, Bergstealt-Lindqvist S, Takahashi M, Matsuda F, Yaoita Y, Takatsu K, Honjo T. Cloning of cDNA for T-Cell Replacing Factor and Identity with B-Cell Growth Factor II Juntendo Medical Journal. 32: 435-441. DOI: 10.14789/Pjmj.32.435  0.31
1986 Kamesaki H, Fukuhara S, Tatsumi E, Uchino H, Yamabe H, Miwa H, Shirakawa S, Hatanaka M, Honjo T. Cytochemical, immunologic, chromosomal, and molecular genetic analysis of a novel cell line derived from Hodgkin's disease Blood. 68: 285-292. DOI: 10.1182/Blood.V68.1.285.285  0.361
1985 Johnson MJ, Natali AM, Cann HM, Honjo T, Cavalli-Sforza LL. Polymorphisms of a human variable heavy chain gene show linkage with constant heavy chain genes. Proceedings of the National Academy of Sciences of the United States of America. 81: 7840-4. PMID 6096861 DOI: 10.1073/Pnas.81.24.7840  0.316
1985 Nishi M, Kataoka T, Honjo T. Preferential rearrangement of the immunoglobulin kappa chain joining region J kappa 1 and J kappa 2 segments in mouse spleen DNA. Proceedings of the National Academy of Sciences of the United States of America. 82: 6399-403. PMID 3931074 DOI: 10.1073/Pnas.82.19.6399  0.326
1985 Takeda S, Naito T, Hama K, Noma T, Honjo T. Construction of chimaeric processed immunoglobulin genes containing mouse variable and human constant region sequences. Nature. 314: 452-4. PMID 3920533 DOI: 10.1038/314452A0  0.365
1985 Ikuta K, Ogura T, Shimizu A, Honjo T. Low frequency of somatic mutation in beta-chain variable region genes of human T-cell receptors. Proceedings of the National Academy of Sciences of the United States of America. 82: 7701-5. PMID 3865189 DOI: 10.1073/Pnas.82.22.7701  0.588
1985 Ishida N, Kanamori H, Noma T, Nikaido T, Sabe H, Suzuki N, Shimizu A, Honjo T. Molecular cloning and structure of the human interleukin 2 receptor gene Nucleic Acids Research. 13: 7579-7589. PMID 2999698 DOI: 10.1093/Nar/13.21.7579  0.371
1985 Horiuchi Y, Honjo T, Ono M. IgE heavy chain constant region genes in atopic dermatitis and senile erythroderma patients. Immunogenetics. 22: 241-6. PMID 2995248 DOI: 10.1007/Bf00404483  0.34
1985 Ueda S, Takenaka O, Honjo T. A truncated immunoglobulin epsilon pseudogene is found in gorilla and man but not in chimpanzee. Proceedings of the National Academy of Sciences of the United States of America. 82: 3712-5. PMID 2987940 DOI: 10.1073/Pnas.82.11.3712  0.305
1985 Shimuzu A, Kondo S, Takeda SI, Yodoi J, Ishida N, Sabe H, Osawa H, Diamantstein T, Nikaido T, Honjo T. Nucleotide sequence of mouse IL-2 receptor cDNA and its comparison with the human IL-2 receptor sequence Nucleic Acids Research. 13: 1505-1516. PMID 2987826 DOI: 10.1093/Nar/13.5.1505  0.331
1985 Yamamura K, Miki T, Suzuki N, Ebihara T, Kawai K, Kumahara Y, Honjo T. Introduction of Mouse Cε Genes into Cos-7 Cells and Fertilized Mouse Eggs Journal of Biochemistry. 97: 333-339. PMID 2987199 DOI: 10.1093/Oxfordjournals.Jbchem.A135058  0.366
1985 Yodoi J, Okada M, Tagaya Y, Teshigawara K, Fukui K, Ishida N, Ikuta K, Maeda M, Honjo T, Osawa H. Rat lymphoid cell lines producing human T cell leukemia virus. II. Constitutive expression of rat interleukin 2 receptor. The Journal of Experimental Medicine. 161: 924-34. PMID 2985731 DOI: 10.1084/Jem.161.5.924  0.59
1984 Yaoita Y, Matsunami N, Choi CY, Sugiyama H, Kishimoto T, Honjo T. The D-JH complex is an intermediate to the complete immunoglobulin heavy-chain V-region gene. Nucleic Acids Research. 11: 7303-16. PMID 6316256 DOI: 10.1093/Nar/11.21.7303  0.311
1984 Nonaka M, Takahashi M, Natsuume-Sakai S, Nonaka M, Tanaka S, Shimizu A, Honjo T. Isolation of cDNA clones specifying the fourth component of mouse complement and its isotype, sex-limited protein. Proceedings of the National Academy of Sciences of the United States of America. 81: 6822-6. PMID 6208559 DOI: 10.1073/Pnas.81.21.6822  0.319
1984 Yamamura K, Kikutani H, Takahashi N, Taga T, Akira S, Kawai K, Fukuchi K, Kumahara Y, Honjo T, Kishimoto T. Introduction of Human γ1 Immunoglobulin Genes into Fertilized Mouse Eggs Journal of Biochemistry. 96: 357-363. PMID 6094517 DOI: 10.1093/Oxfordjournals.Jbchem.A134845  0.352
1984 Nikaido T, Shimizu A, Ishida N, Sabe H, Teshigawara K, Maeda M, Uchiyama T, Yodoi J, Honjo T. Molecular cloning of cDNA encoding human interleukin-2 receptor Nature. 311: 631-635. PMID 6090949 DOI: 10.1038/311631A0  0.331
1984 Takahashi N, Noma T, Honjo T. Rearranged immunoglobulin heavy chain variable region (VH) pseudogene that deletes the second complementarity-determining region. Proceedings of the National Academy of Sciences of the United States of America. 81: 5194-8. PMID 6089186 DOI: 10.1073/Pnas.81.16.5194  0.365
1984 Kataoka T, Kondo S, Nishi M, Kodaira M, Honjo T. Isolation and characterization of endonuclease J: a sequence-specific endonuclease cleaving immunoglobulin genes. Nucleic Acids Research. 12: 5995-6010. PMID 6089106 DOI: 10.1093/Nar/12.15.5995  0.317
1984 Hayashida H, Miyata T, Yamawaki-Kataoka Y, Honjo T, Wels J, Blattner F. Concerted evolution of the mouse immunoglobulin gamma chain genes. The Embo Journal. 3: 2047-2053. DOI: 10.1002/J.1460-2075.1984.Tb02090.X  0.348
1984 Kobayashi N, Konishi H, Sabe H, Shigesada K, Noma T, Honjo T, Hatanaka M. Genomic structure of HTLV (human T-cell leukemia virus): detection of defective genome and its amplification in MT-2 cells. The Embo Journal. 3: 1339-1343. DOI: 10.1002/J.1460-2075.1984.Tb01974.X  0.322
1983 Nakanishi K, Sugimura K, Yaoita Y, Maeda K, Kashiwamura S, Honjo T, Kishimoto T. A T15-idiotype-positive T suppressor hybridoma does not use the T15 VH gene segment. Proceedings of the National Academy of Sciences of the United States of America. 79: 6984-8. PMID 6983692 DOI: 10.1073/Pnas.79.22.6984  0.308
1983 Hisajima H, Nishida Y, Nakai S, Takahashi N, Ueda S, Honjo T. Structure of the human immunoglobulin C epsilon 2 gene, a truncated pseudogene: implications for its evolutionary origin. Proceedings of the National Academy of Sciences of the United States of America. 80: 2995-9. PMID 6407005 DOI: 10.1073/Pnas.80.10.2995  0.744
1983 Migone N, Feder J, Cann H, van West B, Hwang J, Takahashi N, Honjo T, Piazza A, Cavalli-Sforza LL. Multiple DNA fragment polymorphisms associated with immunoglobulin mu chain switch-like regions in man. Proceedings of the National Academy of Sciences of the United States of America. 80: 467-71. PMID 6300846 DOI: 10.1073/Pnas.80.2.467  0.336
1983 Seno M, Kurokawa T, Ono Y, onda H, Sasada R, lagarshi K, kikuchi M, Sugino Y, Nishida Y, Honjo T. Molecular cloning and nucleotide sequencing of human immunoglobulin € chain cDNA Nucleic Acids Research. 11: 719-726. PMID 6300763 DOI: 10.1093/Nar/11.3.719  0.75
1983 Kataoka T, Takeda S, Honjo T. Escherichia coli extract-catalyzed recombination in switch regions of mouse immunoglobulin genes. Proceedings of the National Academy of Sciences of the United States of America. 80: 2666-70. PMID 6221341 DOI: 10.1073/Pnas.80.9.2666  0.353
1982 Yaoita Y, Kumagai Y, Okumura K, Honjo T. Expression of lymphocyte surface IgE does not require switch recombination Nature. 297: 697-699. PMID 6979716 DOI: 10.1038/297697A0  0.388
1982 Takahashi N, Ueda S, Obata M, Nikaido T, Nakai S, Honjo T. Structure of human immunoglobulin gamma genes: implications for evolution of a gene family. Cell. 29: 671-9. PMID 6811139 DOI: 10.1016/0092-8674(82)90183-0  0.326
1982 Nishida Y, Miki T, Hisajima H, Honjo T. Cloning of human immunoglobulin epsilon chain genes: evidence for multiple C epsilon genes. Proceedings of the National Academy of Sciences of the United States of America. 79: 3833-7. PMID 6808515 DOI: 10.1073/Pnas.79.12.3833  0.759
1982 Shimizu A, Takahashi N, Yaoita Y, Honjo T. Organization of the constant-region gene family of the mouse immunoglobulin heavy chain. Cell. 28: 499-506. PMID 6804095 DOI: 10.1016/0092-8674(82)90204-5  0.361
1982 Honjo T, Nakai S, Nishida Y, Kataoka T, Yamawaki-Kataoka Y, Takahashi N, Obata M, Shimizu A, Yaoita Y, Nikaido T, Ishida N. Rearrangements of immunoglobulin genes during differentiation and evolution. Immunological Reviews. 59: 33-67. PMID 6796498 DOI: 10.1111/J.1600-065X.1981.Tb00455.X  0.764
1982 Sakoyama Y, Yaoita Y, Honjo T. Immunoglobulin switch region-like sequences in Drosophila melanogaster. Nucleic Acids Research. 10: 4203-14. PMID 6289266 DOI: 10.1093/Nar/10.14.4203  0.308
1982 Shimizu A, Hamaguchi Y, Yaoita Y, Moriwaki K, Kondo K, Honjo T. Japanese wild mouse, Mus musculus molossinus, has duplicated immunoglobulin gamma 2a genes. Nature. 298: 82-4. PMID 6283372 DOI: 10.1038/298082A0  0.359
1982 Taniguchi M, Tokuhisa T, Kanno M, Honjo T. An antigen-specific suppressor T cell factor controlled by two genes in the immunoglobulin heavy chain linkage group and in the I-J subregion of the H-2 complex. Current Topics in Microbiology and Immunology. 100: 33-41. PMID 6212196 DOI: 10.1007/978-3-642-68586-6_4  0.368
1982 Taniguchi M, Tokuhisa T, Kanno M, Yaoita Y, Shimizu A, Honjo T. Reconstitution of antigen-specific suppressor activity with translation products of mRNA Nature. 298: 172-174. PMID 6211624 DOI: 10.1038/298172A0  0.337
1982 Ishida N, Ueda S, Hayashida H, Miyata T, Honjo T. The nucleotide sequence of the mouse immunoglobulin epsilon gene: comparison with the human epsilon gene sequence. The Embo Journal. 1: 1117-1123. DOI: 10.1002/J.1460-2075.1982.Tb01306.X  0.372
1981 Nikaido T, Nakai S, Honjo T. Switch region of immunoglobulin Cmu gene is composed of simple tandem repetitive sequences. Nature. 292: 845-8. PMID 6791031 DOI: 10.1038/292845A0  0.358
1981 Honjo T, Kataoka T, Yaoita Y, Shimizu A, Takahashi N, Yamawaki-Kataoka Y, Nikaido T, Nakai S, Obata M, Kawakami T, Nishida Y. Organization and reorganization of immunoglobulin heavy-chain genes. Cold Spring Harbor Symposia On Quantitative Biology. 913-23. PMID 6790223 DOI: 10.1101/Sqb.1981.045.01.108  0.738
1981 Obata M, Kataoka T, Nakai S, Yamagishi H, Takahashi N, Yamawaki-Kataoka Y, Nikaido T, Shimizu A, Honjo T. Structure of a rearranged gamma 1 chain gene and its implication to immunoglobulin class-switch mechanism. Proceedings of the National Academy of Sciences of the United States of America. 78: 2437-41. PMID 6787603 DOI: 10.1073/Pnas.78.4.2437  0.363
1981 Kataoka T, Miyata T, Honjo T. Repetitive sequences in class-switch recombination regions of immunoglobulin heavy chain genes. Cell. 23: 357-68. PMID 6781756 DOI: 10.1016/0092-8674(81)90131-8  0.349
1981 Shimizu A, Takahashi N, Yamawaki-Kataoka Y, Nishida Y, Kataoka T, Honjo T. Ordering of mouse immunoglobulin heavy chain genes by molecular cloning. Nature. 289: 149-53. PMID 6779206 DOI: 10.1038/289149A0  0.76
1981 Takahashi N, Nakai S, Honjo T. Cloning of human immunoglobulin mu gene and comparison with mouse mu gene. Nucleic Acids Research. 8: 5983-91. PMID 6450943 DOI: 10.1093/Nar/8.24.5983  0.366
1981 Nishida Y, Kataoka T, Ishida N, Nakai S, Kishimoto T, Böttcher I, Honjo T. Cloning of mouse immunoglobulin epsilon gene and its location within the heavy chain gene cluster. Proceedings of the National Academy of Sciences of the United States of America. 78: 1581-5. PMID 6262816 DOI: 10.1073/Pnas.78.3.1581  0.769
1981 Yamawaki-Kataoka Y, Miyata T, Honjo T. The complete nucleotide sequence of mouse immunoglobin gamma 2a gene and evolution of heavy chain genes: further evidence for intervening sequence-mediated domain transfer. Nucleic Acids Research. 9: 1365-81. PMID 6262729 DOI: 10.1093/Nar/9.6.1365  0.341
1981 Kawakami T, Takahashi N, Honjo T. Complete nucleotide sequence of mouse immunoglobulin mu gene and comparison with other immunoglobulin heavy chain genes. Nucleic Acids Research. 8: 3933-45. PMID 6255422 DOI: 10.1093/Nar/8.17.3933  0.359
1980 Yaoita Y, Honjo T. Deletion of immunoglobulin heavy chain genes from expressed allelic chromosome. Nature. 286: 850-3. PMID 6774261 DOI: 10.1038/286850A0  0.359
1980 Obata M, Yamawaki-Kataoka Y, Takahashi N, Kataoka T, Shimizu A, Mano Y, Seidman JG, Peterlin BM, Leder P, Honjo T. Immunoglobulin gamma 1 heavy chain gene: structural gene sequences cloned in a bacterial plasmid. Gene. 9: 87-97. PMID 6769752 DOI: 10.1016/0378-1119(80)90168-7  0.621
1980 Miyata T, Yasunaga T, Yamawaki-Kataoka Y, Obata M, Honjo T. Nucleotide sequence divergence of mouse immunoglobulin gamma 1 and gamma 2b chain genes and the hypothesis of intervening sequence-mediated domain transfer. Proceedings of the National Academy of Sciences of the United States of America. 77: 2143-7. PMID 6769121 DOI: 10.1073/Pnas.77.4.2143  0.31
1980 Kataoka T, Kawakami T, Takahashi N, Honjo T. Rearrangement of immunoglobulin gamma 1-chain gene and mechanism for heavy-chain class switch. Proceedings of the National Academy of Sciences of the United States of America. 77: 919-23. PMID 6767246 DOI: 10.1073/Pnas.77.2.919  0.356
1980 Yamawaki-Kataoka Y, Kataoka T, Takahashi N, Obata M, Honjo T. Complete nucleotide sequence of immunoglobulin gamma2b chain gene cloned from newborn nouse DNA. Nature. 283: 786-9. PMID 6766534 DOI: 10.1038/283786A0  0.364
1980 Mishima Y, Kominami R, Honjo T, Muramatsu M. Cloning and determination of a putative promoter region of a mouse ribosomal deoxyribonucleic acid fragment. Biochemistry. 19: 3780-6. PMID 6250576 DOI: 10.1021/Bi00557A020  0.314
1980 Kataoka T, Yamawaki-Kataoka Y, Yamagishi H, Honjo T. Cloning immunoglobulin gamma 2b chain gene of mouse: characterization and partial sequence determination. Proceedings of the National Academy of Sciences of the United States of America. 76: 4240-4. PMID 116231 DOI: 10.1073/Pnas.76.9.4240  0.351
1980 Honjo T, Obata M, Yamawaki-Katoaka Y, Kataoka T, Kawakami T, Takahashi N, Mano Y. Cloning and complete nucleotide sequence of mouse immunoglobulin gamma 1 chain gene. Cell. 18: 559-68. PMID 115593 DOI: 10.1016/0092-8674(79)90072-2  0.368
1980 YAOITA Y, HONJO T. DELETION OF IMMUNOGLOBULIN HEAVY CHAIN GENES ACCOMPANIES THE CLASS SWITCH REARRANGEMENT Biomedical Research. 1: 164-175. DOI: 10.2220/Biomedres.1.164  0.319
1979 Yamawaki-Kataoka Y, Sato K, Shimizu A, Kataoka T, Mano Y, Ono M, Kawakami M, Honjo T. Mutual homology of mouse immunoglobulin gamma-chain gene sequences. Biochemistry. 18: 490-4. PMID 105754 DOI: 10.1021/Bi00570A018  0.342
1978 Honjo T, Kataoka T. Organization of immunoglobulin heavy chain genes and allelic deletion model. Proceedings of the National Academy of Sciences of the United States of America. 75: 2140-4. PMID 97665 DOI: 10.1073/Pnas.75.5.2140  0.348
1977 Leder P, Honjo T, Seidman J, Swan D. Origin of immunoglobulin gene diversity: the evidence and a restriction-modification model. Cold Spring Harbor Symposia On Quantitative Biology. 41: 855-62. PMID 408082 DOI: 10.1101/Sqb.1977.041.01.095  0.607
1976 Honjo T, Packman S. Quantitation of constant and variable region genes for mouse immunoglobulin lambda chains. Biochemistry. 15: 2780-5. PMID 820372 DOI: 10.1021/Bi00658A012  0.358
1976 Honjo T, Swan D, Packman S, Polsky F, Leder P. Purification and translation of an immunoglobulin lambda chain messenger RNA from mouse myeloma. Biochemistry. 15: 2775-9. PMID 59605 DOI: 10.1021/Bi00658A011  0.507
1974 Honjo T, Reeder RH. Transcription of Xenopus chromatin by homologous ribonucleic acid polymerase: aberrant synthesis of ribosomal and 5S ribonucleic acid. Biochemistry. 13: 1896-9. PMID 4857734 DOI: 10.1021/Bi00706A018  0.571
1974 Leder P, Honjo T, Packman S, Swan D, Nau M, Norman B. The organization and diversity of immunoglobulin genes. Proceedings of the National Academy of Sciences of the United States of America. 71: 5109-15. PMID 4531042 DOI: 10.1073/Pnas.71.12.5109  0.539
1974 Honjo T, Packman S, Swan D, Nau M, Leder P. Organization of immunoglobulin genes: reiteration frequency of the mouse kappa chain constant region gene. Proceedings of the National Academy of Sciences of the United States of America. 71: 3659-63. PMID 4215083 DOI: 10.1073/Pnas.71.9.3659  0.544
1973 Honjo T, Reeder RH. Preferential transcription of Xenopus laevis ribosomal RNA in interspecies hybrids between Xenopus laevis and Xenopus mulleri. Journal of Molecular Biology. 80: 217-28. PMID 4763983 DOI: 10.1016/0022-2836(73)90168-X  0.56
1973 Honjo T, Hayaishi O. Enzymatic ADP-ribosylation of proteins and regulation of cellular activity Current Topics in Cellular Regulation. 7: 87-127. PMID 4360798 DOI: 10.1016/B978-0-12-152807-2.50011-5  0.576
1971 Honjo T, Nishizuka Y. [114] Enzymatic preparation of nicotinic acid adenine dinucleotide, nicotinic acid ribonucleotide, and nicotinic acid ribonucleoside Methods in Enzymology. 18: 132-137. DOI: 10.1016/S0076-6879(71)18071-8  0.59
1969 Honjo T, Nishizuka Y, Hayaishi O. Adenosine diphosphoribosylation of aminoacyl transferase II by diphtheria toxin. Cold Spring Harbor Symposia On Quantitative Biology. 34: 603-8. PMID 4314916 DOI: 10.1101/Sqb.1969.034.01.069  0.689
1968 Nakazawa K, Ueda K, Honjo T, Yoshihara K, Nishizuka Y, Hayaishi O. Nicotinamide adenine dinucleotide glycohydrolases and poly adenosine diphosphate ribose synthesis in rat liver. Biochemical and Biophysical Research Communications. 32: 143-9. PMID 5672131 DOI: 10.1016/0006-291X(68)90360-4  0.691
1968 Ueda K, Reeder RH, Honjo T, Nishizuka Y, Hayaishi O. Poly adenosine diphosphate ribose synthesis associated with chromatin. Biochemical and Biophysical Research Communications. 31: 379-85. PMID 5653649 DOI: 10.1016/0006-291X(68)90486-5  0.752
1968 Nishizuka Y, Ueda K, Nakazawa L, Reeder RH, Honjo T. Poly adenosine diphosphate ribose synthesis and nicotinamide adenine dinucleotide transglycosidases. The Journal of Vitaminology. 14: Suppl:143-52. PMID 4299894 DOI: 10.5925/Jnsv1954.14.Supplement_143  0.705
1966 Honjo T, Nakamura S, Nishizuka Y, Hayaishi O. Stoichiometric utilization of adenosine 5'-triphosphate in nicotinate ribonucleotide synthesis from nicotinate and 5-phosphoribosyl-1-pyrophosphate. Biochemical and Biophysical Research Communications. 25: 199-204. PMID 4291351 DOI: 10.1016/0006-291X(66)90580-8  0.685
1964 HONJO T, IKEDA M, ANDREOLI AJ, NISHIZUKA Y, HAYAISHI O. ENZYMIC PREPARATION OF NICOTINATE ADENINE DINUCLEOTIDE (DEAMIDO-NAD). Biochimica Et Biophysica Acta. 89: 549-52. PMID 14209340 DOI: 10.1016/0926-6569(64)90084-7  0.688
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