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Salvatore V. Pizzo - Publications

Affiliations: 
Pathology Duke University School of Medicine, Durham, NC, United States 
Area:
proteolytic events in angiogenesis, regulation of cellular growth, and immune regulation
Website:
http://mstp.duke.edu/faculty/details/0062415
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302 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Gopal U, Pizzo SV. Cell surface GRP78 signaling: An emerging role as a transcriptional modulator in cancer. Journal of Cellular Physiology. PMID 32864780 DOI: 10.1002/Jcp.30030  0.302
2020 Bastida-Ruiz D, Wuillemin C, Pederencino A, Yaron M, Martinez de Tejada B, Pizzo SV, Cohen M. Activated α-macroglobulin binding to cell surface GRP78 induces trophoblastic cell fusion. Scientific Reports. 10: 9666. PMID 32541810 DOI: 10.1038/S41598-020-66554-0  0.354
2019 Gopal U, Mowery Y, Young K, Pizzo SV. Targeting cell surface-associated GRP78 enhances pancreatic cancer radiosensitivity by reducing YAP/TAZ protein signaling. The Journal of Biological Chemistry. PMID 31358620 DOI: 10.1074/Jbc.Ra119.009091  0.619
2017 Al-Hashimi AA, Lebeau P, Majeed F, Polena E, Lhotak Š, Collins CAF, Pinthus JH, Gonzalez-Gronow M, Hoogenes J, Pizzo SV, Crowther M, Kapoor A, Rak J, Gyulay G, D'Angelo S, et al. Autoantibodies against the cell surface-associated chaperone GRP78 stimulate tumor growth via tissue factor. The Journal of Biological Chemistry. PMID 29066620 DOI: 10.1074/Jbc.M117.799908  0.344
2017 Bellezza I, Scarpelli P, Pizzo SV, Grottelli S, Costanzi E, Minelli A. ROS-independent Nrf2 activation in prostate cancer. Oncotarget. 8: 67506-67518. PMID 28978049 DOI: 10.18632/Oncotarget.18724  0.327
2017 Jensen BC, Bultman SJ, Holley D, Tang W, de Ridder G, Pizzo S, Bowles D, Willis MS. Upregulation of autophagy genes and the unfolded protein response in human heart failure. International Journal of Clinical and Experimental Medicine. 10: 1051-1058. PMID 28794819  0.652
2017 Gonzalez-Gronow M, Fiedler JL, Farias Gomez C, Wang F, Ray R, Ferrell PD, Pizzo SV. Myelin basic protein stimulates plasminogen activation via tissue plasminogen activator following binding to independent l-lysine-containing domains. Biochemical and Biophysical Research Communications. PMID 28648598 DOI: 10.1016/J.Bbrc.2017.06.131  0.321
2015 Al-Hashimi AA, Caldwell J, Gonzalez-Gronow M, Pizzo SV, Aboumrad D, Pozza L, Al-Bayati H, Weitz JI, Stafford A, Chan H, Kapoor A, Jacobsen DW, Dickhout JG, Austin RC. Binding of anti-GRP78 autoantibodies to cell surface GRP78 increases tissue factor procoagulant activity via the release of calcium from endoplasmic reticulum stores. The Journal of Biological Chemistry. 290: 28725. PMID 26614782 DOI: 10.1074/Jbc.A110.119107  0.303
2015 de Ridder GG, Lundblad RL, Pizzo SV. Actions of Thrombin in the Interstitium. Journal of Thrombosis and Haemostasis : Jth. PMID 26564405 DOI: 10.1111/Jth.13191  0.688
2015 Li S, Payne S, Wang F, Claus P, Su Z, Groth J, Geradts J, de Ridder G, Alvarez R, Marcom PK, Pizzo SV, Bachelder RE. Nuclear basic fibroblast growth factor regulates triple-negative breast cancer chemo-resistance. Breast Cancer Research : Bcr. 17: 91. PMID 26141457 DOI: 10.1186/S13058-015-0590-3  0.681
2015 Misra UK, Pizzo SV. Activated α2-macroglobulin binding to human prostate cancer cells triggers insulin-like responses. The Journal of Biological Chemistry. 290: 9571-87. PMID 25720493 DOI: 10.1074/Jbc.M114.617837  0.345
2014 Gonzalez-Gronow M, Gomez CF, de Ridder GG, Ray R, Pizzo SV. Binding of tissue-type plasminogen activator to the glucose-regulated protein 78 (GRP78) modulates plasminogen activation and promotes human neuroblastoma cell proliferation in vitro. The Journal of Biological Chemistry. 289: 25166-76. PMID 25059665 DOI: 10.1074/Jbc.M114.589341  0.722
2014 Misra UK, Pizzo SV. Activated α2-macroglobulin binding to cell surface GRP78 induces T-loop phosphorylation of Akt1 by PDK1 in association with Raptor. Plos One. 9: e88373. PMID 24516643 DOI: 10.1371/Journal.Pone.0088373  0.341
2013 Misra UK, Payne S, Pizzo SV. The monomeric receptor binding domain of tetrameric α2-macroglobulin binds to cell surface GRP78 triggering equivalent activation of signaling cascades. Biochemistry. 52: 4014-25. PMID 23721263 DOI: 10.1021/Bi400376S  0.374
2013 Misra UK, Pizzo SV. Evidence for a pro-proliferative feedback loop in prostate cancer: the role of Epac1 and COX-2-dependent pathways. Plos One. 8: e63150. PMID 23646189 DOI: 10.1371/Journal.Pone.0063150  0.311
2013 Gonzalez-Gronow M, Ray R, Wang F, Pizzo SV. The voltage-dependent anion channel (VDAC) binds tissue-type plasminogen activator and promotes activation of plasminogen on the cell surface. The Journal of Biological Chemistry. 288: 498-509. PMID 23161549 DOI: 10.1074/Jbc.M112.412502  0.352
2013 Ridder GGd, Ray R, Pizzo SV. Abstract 5248: Tunneling nanotubes connect melanoma cells and mediate transfer of mitochondria and GRP78. Cancer Research. 73: 5248-5248. DOI: 10.1158/1538-7445.Am2013-5248  0.304
2013 Ray R, Ridder Gd, Pizzo SV. Abstract 1247: Development of GRP78 scFv-Subtilase fusion proteins for sensitization of melanoma to chemotherapeutics. Cancer Research. 73: 1247-1247. DOI: 10.1158/1538-7445.Am2013-1247  0.335
2012 Cianciolo GJ, Pizzo SV. Anti-inflammatory and vasoprotective activity of a retroviral-derived peptide, homologous to human endogenous retroviruses: endothelial cell effects. Plos One. 7: e52693. PMID 23285152 DOI: 10.1371/Journal.Pone.0052693  0.317
2012 Misra UK, Pizzo SV. Receptor-recognized α₂-macroglobulin binds to cell surface-associated GRP78 and activates mTORC1 and mTORC2 signaling in prostate cancer cells. Plos One. 7: e51735. PMID 23272152 DOI: 10.1371/Journal.Pone.0051735  0.35
2012 Ray R, de Ridder GG, Eu JP, Paton AW, Paton JC, Pizzo SV. The Escherichia coli subtilase cytotoxin A subunit specifically cleaves cell-surface GRP78 protein and abolishes COOH-terminal-dependent signaling. The Journal of Biological Chemistry. 287: 32755-69. PMID 22851173 DOI: 10.1074/Jbc.M112.399808  0.709
2012 de Ridder GG, Ray R, Pizzo SV. A murine monoclonal antibody directed against the carboxyl-terminal domain of GRP78 suppresses melanoma growth in mice. Melanoma Research. 22: 225-35. PMID 22495669 DOI: 10.1097/Cmr.0B013E32835312Fd  0.712
2012 Bowers EV, Bond JE, Cianciolo GJ, Pizzo SV. α<sub>2</sub>-macroglobulin co-administered <i>in vivo</i> promotes antigen delivery and presentation Open Journal of Immunology. 2: 72-77. DOI: 10.4236/Oji.2012.22009  0.725
2011 Selim MA, Burchette JL, Bowers EV, de Ridder GG, Mo L, Pizzo SV, Gonzalez-Gronow M. Changes in oligosaccharide chains of autoantibodies to GRP78 expressed during progression of malignant melanoma stimulate melanoma cell growth and survival. Melanoma Research. 21: 323-34. PMID 21597391 DOI: 10.1097/Cmr.0B013E3283471042  0.785
2011 Misra UK, Mowery YM, Gawdi G, Pizzo SV. Loss of cell surface TFII-I promotes apoptosis in prostate cancer cells stimulated with activated α₂ -macroglobulin. Journal of Cellular Biochemistry. 112: 1685-95. PMID 21503958 DOI: 10.1002/Jcb.23083  0.631
2011 de Ridder G, Ray R, Misra UK, Pizzo SV. Modulation of the unfolded protein response by GRP78 in prostate cancer. Methods in Enzymology. 489: 245-57. PMID 21266234 DOI: 10.1016/B978-0-12-385116-1.00014-5  0.712
2011 de Ridder GG, Gonzalez-Gronow M, Ray R, Pizzo SV. Autoantibodies against cell surface GRP78 promote tumor growth in a murine model of melanoma. Melanoma Research. 21: 35-43. PMID 21164368 DOI: 10.1097/Cmr.0B013E3283426805  0.703
2011 Misra UK, Payne S, Pizzo SV. Ligation of prostate cancer cell surface GRP78 activates a proproliferative and antiapoptotic feedback loop: a role for secreted prostate-specific antigen. The Journal of Biological Chemistry. 286: 1248-59. PMID 21056970 DOI: 10.1074/Jbc.M110.129767  0.331
2010 Jockheck-Clark AR, Bowers EV, Totonchy MB, Neubauer J, Pizzo SV, Nicchitta CV. Re-examination of CD91 function in GRP94 (glycoprotein 96) surface binding, uptake, and peptide cross-presentation. Journal of Immunology (Baltimore, Md. : 1950). 185: 6819-30. PMID 21048103 DOI: 10.4049/Jimmunol.1000448  0.734
2010 Mowery YM, Weinberg JB, Kennedy MN, Bond KM, Moore JO, Lanasa MC, Gockerman JP, Diehl LF, Pizzo SV, Cianciolo GJ, Friedman DR. LMP-420: a novel purine nucleoside analog with potent cytotoxic effects for CLL cells and minimal toxicity for normal hematopoietic cells. Leukemia. 24: 1580-7. PMID 20613784 DOI: 10.1038/Leu.2010.150  0.621
2010 Al-Hashimi AA, Caldwell J, Gonzalez-Gronow M, Pizzo SV, Aboumrad D, Pozza L, Al-Bayati H, Weitz JI, Stafford A, Chan H, Kapoor A, Jacobsen DW, Dickhout JG, Austin RC. Binding of anti-GRP78 autoantibodies to cell surface GRP78 increases tissue factor procoagulant activity via the release of calcium from endoplasmic reticulum stores. The Journal of Biological Chemistry. 285: 28912-23. PMID 20605795 DOI: 10.1074/Jbc.M110.119107  0.339
2010 Gonzalez-Gronow M, Cuchacovich M, Francos R, Cuchacovich S, Fernandez Mdel P, Blanco A, Bowers EV, Kaczowka S, Pizzo SV. Antibodies against the voltage-dependent anion channel (VDAC) and its protective ligand hexokinase-I in children with autism. Journal of Neuroimmunology. 227: 153-61. PMID 20576296 DOI: 10.1016/J.Jneuroim.2010.06.001  0.721
2010 Misra UK, Pizzo SV. Ligation of cell surface GRP78 with antibody directed against the COOH-terminal domain of GRP78 suppresses Ras/MAPK and PI 3-kinase/AKT signaling while promoting caspase activation in human prostate cancer cells. Cancer Biology & Therapy. 9: 142-52. PMID 20368692 DOI: 10.4161/Cbt.9.2.10422  0.334
2010 Misra UK, Kaczowka S, Pizzo SV. Inhibition of NF-kappaB1 and NF-kappaB2 activation in prostate cancer cells treated with antibody against the carboxyl terminal domain of GRP78: effect of p53 upregulation. Biochemical and Biophysical Research Communications. 392: 538-42. PMID 20097177 DOI: 10.1016/J.Bbrc.2010.01.058  0.346
2010 Misra UK, Pizzo SV. Modulation of the unfolded protein response in prostate cancer cells by antibody-directed against the carboxyl-terminal domain of GRP78. Apoptosis : An International Journal On Programmed Cell Death. 15: 173-82. PMID 20091233 DOI: 10.1007/S10495-009-0430-Y  0.391
2010 Misra UK, Pizzo SV. PFT-alpha inhibits antibody-induced activation of p53 and pro-apoptotic signaling in 1-LN prostate cancer cells. Biochemical and Biophysical Research Communications. 391: 272-6. PMID 19913499 DOI: 10.1016/J.Bbrc.2009.11.048  0.362
2010 Mowery YM, Pizzo SV. Cell surface ATP synthase: A potential target for anti-angiogenic therapy Extracellular Atp and Adenosine as Regulators of Endothelial Cell Function: Implications For Health and Disease. 139-159. DOI: 10.1007/978-90-481-3435-9_9  0.531
2009 Misra UK, Pizzo SV. Epac1-induced cellular proliferation in prostate cancer cells is mediated by B-Raf/ERK and mTOR signaling cascades. Journal of Cellular Biochemistry. 108: 998-1011. PMID 19725049 DOI: 10.1002/Jcb.22333  0.33
2009 Mowery YM, Pizzo SV. The antitumorigenic trifecta. Blood. 114: 1727-8. PMID 19713480 DOI: 10.1182/Blood-2009-06-226233  0.567
2009 Bowers EV, Horvath JJ, Bond JE, Cianciolo GJ, Pizzo SV. Antigen delivery by alpha(2)-macroglobulin enhances the cytotoxic T lymphocyte response. Journal of Leukocyte Biology. 86: 1259-68. PMID 19652028 DOI: 10.1189/Jlb.1008653  0.762
2009 Benvegnù S, Franciotta D, Sussman J, Bachi A, Zardini E, Torreri P, Govaerts C, Pizzo S, Legname G. Prion protein paralog doppel protein interacts with alpha-2-macroglobulin: a plausible mechanism for doppel-mediated neurodegeneration. Plos One. 4: e5968. PMID 19536284 DOI: 10.1371/Journal.Pone.0005968  0.389
2009 Mavropoulos JC, Buschemeyer WC, Tewari AK, Rokhfeld D, Pollak M, Zhao Y, Febbo PG, Cohen P, Hwang D, Devi G, Demark-Wahnefried W, Westman EC, Peterson BL, Pizzo SV, Freedland SJ. The effects of varying dietary carbohydrate and fat content on survival in a murine LNCaP prostate cancer xenograft model. Cancer Prevention Research (Philadelphia, Pa.). 2: 557-65. PMID 19470786 DOI: 10.1158/1940-6207.Capr-08-0188  0.724
2009 Misra UK, Mowery Y, Kaczowka S, Pizzo SV. Ligation of cancer cell surface GRP78 with antibodies directed against its COOH-terminal domain up-regulates p53 activity and promotes apoptosis. Molecular Cancer Therapeutics. 8: 1350-62. PMID 19417154 DOI: 10.1158/1535-7163.Mct-08-0990  0.626
2009 Gonzalez-Gronow M, Selim MA, Papalas J, Pizzo SV. GRP78: a multifunctional receptor on the cell surface. Antioxidants & Redox Signaling. 11: 2299-306. PMID 19331544 DOI: 10.1089/Ars.2009.2568  0.373
2009 Misra UK, Wang F, Pizzo SV. Transcription factor TFII-I causes transcriptional upregulation of GRP78 synthesis in prostate cancer cells. Journal of Cellular Biochemistry. 106: 381-9. PMID 19097122 DOI: 10.1002/Jcb.22016  0.406
2009 Freedland SJ, Mavropoulos JC, Buschemeyer WC, Tewari AK, Rokhfeld D, Pollak M, Zhao Y, Febbo PG, Cohen P, Hwang D, Devi G, Demark-Wahnefried W, Westman EC, Peterson BL, Pizzo SV. A NO CARBOHYDRATE DIET SIGNIFICANTLY PROLONGS SURVIVAL IN A PROSTATE CANCER XENOGRAFT MODEL VIA IGF-1 AND GLOBAL GENE EXPRESSION CHANGES Journal of Urology. 181: 47-47. DOI: 10.1016/S0022-5347(09)60144-0  0.71
2008 Mowery YM, Pizzo SV. Targeting cell surface F1F0 ATP synthase in cancer therapy. Cancer Biology & Therapy. 7: 1836-8. PMID 18981725 DOI: 10.4161/Cbt.7.11.7155  0.59
2008 Quinones QJ, de Ridder GG, Pizzo SV. GRP78: a chaperone with diverse roles beyond the endoplasmic reticulum. Histology and Histopathology. 23: 1409-16. PMID 18785123 DOI: 10.14670/Hh-23.1409  0.791
2008 Lillis AP, Greenlee MC, Mikhailenko I, Pizzo SV, Tenner AJ, Strickland DK, Bohlson SS. Murine low-density lipoprotein receptor-related protein 1 (LRP) is required for phagocytosis of targets bearing LRP ligands but is not required for C1q-triggered enhancement of phagocytosis. Journal of Immunology (Baltimore, Md. : 1950). 181: 364-73. PMID 18566402 DOI: 10.4049/Jimmunol.181.1.364  0.76
2008 Misra UK, Kaczowka S, Pizzo SV. The cAMP-activated GTP exchange factor, Epac1 upregulates plasma membrane and nuclear Akt kinase activities in 8-CPT-2-O-Me-cAMP-stimulated macrophages: Gene silencing of the cAMP-activated GTP exchange Epac1 prevents 8-CPT-2-O-Me-cAMP activation of Akt activity in macrophages. Cellular Signalling. 20: 1459-70. PMID 18495429 DOI: 10.1016/J.Cellsig.2008.04.002  0.301
2008 McLachlan JB, Shelburne CP, Hart JP, Pizzo SV, Goyal R, Brooking-Dixon R, Staats HF, Abraham SN. Mast cell activators: a new class of highly effective vaccine adjuvants. Nature Medicine. 14: 536-41. PMID 18425129 DOI: 10.1038/Nm1757  0.559
2008 Misra UK, Pizzo SV. Heterotrimeric Galphaq11 co-immunoprecipitates with surface-anchored GRP78 from plasma membranes of alpha2M*-stimulated macrophages. Journal of Cellular Biochemistry. 104: 96-104. PMID 18213612 DOI: 10.1002/Jcb.21607  0.369
2008 Freedland SJ, Mavropoulos J, Wang A, Darshan M, Demark-Wahnefried W, Aronson WJ, Cohen P, Hwang D, Peterson B, Fields T, Pizzo SV, Isaacs WB. Carbohydrate restriction, prostate cancer growth, and the insulin-like growth factor axis. The Prostate. 68: 11-9. PMID 17999389 DOI: 10.1002/Pros.20683  0.715
2008 Kaczowka SJ, Madding LS, Epting KL, Kelly RM, Cianciolo GJ, Pizzo SV. Probing the stability of native and activated forms of alpha2-macroglobulin. International Journal of Biological Macromolecules. 42: 62-7. PMID 17996290 DOI: 10.1016/J.Ijbiomac.2007.09.019  0.349
2008 Misra UK, Kaczowka SJ, Pizzo SV. Interaction between TCL1 and Epac1 in the activation of Akt kinases in plasma membranes and nuclei of 8-CPT-2-O-Me-cAMP-stimulated macrophages. Cellular Signalling. 20: 130-8. PMID 17993260 DOI: 10.1016/J.Cellsig.2007.10.008  0.313
2008 Gonzalez-Gronow M, Kaczowka S, Gawdi G, Pizzo SV. Dipeptidyl peptidase IV (DPP IV/CD26) is a cell-surface plasminogen receptor. Frontiers in Bioscience : a Journal and Virtual Library. 13: 1610-8. PMID 17981653 DOI: 10.2741/2785  0.375
2008 Anderson RB, Cianciolo GJ, Kennedy MN, Pizzo SV. Alpha 2-macroglobulin binds CpG oligodeoxynucleotides and enhances their immunostimulatory properties by a receptor-dependent mechanism. Journal of Leukocyte Biology. 83: 381-92. PMID 17967834 DOI: 10.1189/Jlb.0407236  0.61
2008 Schmidt C, Lepsverdize E, Chi SL, Das AM, Pizzo SV, Dityatev A, Schachner M. Amyloid precursor protein and amyloid beta-peptide bind to ATP synthase and regulate its activity at the surface of neural cells. Molecular Psychiatry. 13: 953-69. PMID 17726461 DOI: 10.1038/Sj.Mp.4002077  0.703
2008 Buschemeyer WC, Tewari A, Hsu D, Mavropoulos J, Rokhfeld D, Johnson T, Pizzo S, Febbo PG, Freedland SJ. ELIMINATION OF DIETARY CARBOHYDRATE EXTENDS SURVIVAL OF MICE BEARING LNCAP XENOGRAFTS Journal of Urology. 179: 226-226. DOI: 10.1016/S0022-5347(08)60651-5  0.703
2007 Gonzalez-Gronow M, Kaczowka SJ, Payne S, Wang F, Gawdi G, Pizzo SV. Plasminogen structural domains exhibit different functions when associated with cell surface GRP78 or the voltage-dependent anion channel. The Journal of Biological Chemistry. 282: 32811-20. PMID 17848573 DOI: 10.1074/Jbc.M703342200  0.311
2007 Chi SL, Wahl ML, Mowery YM, Shan S, Mukhopadhyay S, Hilderbrand SC, Kenan DJ, Lipes BD, Johnson CE, Marusich MF, Capaldi RA, Dewhirst MW, Pizzo SV. Angiostatin-like activity of a monoclonal antibody to the catalytic subunit of F1F0 ATP synthase. Cancer Research. 67: 4716-24. PMID 17510399 DOI: 10.1158/0008-5472.Can-06-1094  0.78
2007 Bond JE, Cianciolo GJ, Pizzo SV. Incorporation of low molecular weight molecules into alpha(2)-macroglobulin by nucleophilic exchange. Biochemical and Biophysical Research Communications. 357: 433-8. PMID 17428443 DOI: 10.1016/J.Bbrc.2007.03.151  0.37
2007 Misra UK, Pizzo SV. Upregulation of AKT1 protein expression in forskolin-stimulated macrophage: evidence from ChIP analysis that CREB binds to and activates the AKT1 promoter. Journal of Cellular Biochemistry. 100: 1022-33. PMID 17152074 DOI: 10.1002/Jcb.21086  0.325
2007 Buschemeyer WC, Mavropoulos J, Pizzo S, Demark-Wahnefried W, Westman E, Freedland SJ. 536: Effect of Diet on Lncap Prostate Cancer Growth and Survival in Scid Mice Journal of Urology. 177: 178-178. DOI: 10.1016/S0022-5347(18)30776-6  0.71
2007 Freedland SJ, Mavropoulos J, Wang A, Darshan M, Demark-Wahnefried W, Pizzo S, Aronson WJ, Cohen P, Isaacs WB. 145: A No-Carbohydrate Diet Significantly Delays Prostate Cancer Growth in an Animal Model Journal of Urology. 177: 50-50. DOI: 10.1016/S0022-5347(18)30410-5  0.708
2006 Gonzalez-Gronow M, Cuchacovich M, Llanos C, Urzua C, Gawdi G, Pizzo SV. Prostate cancer cell proliferation in vitro is modulated by antibodies against glucose-regulated protein 78 isolated from patient serum. Cancer Research. 66: 11424-31. PMID 17145889 DOI: 10.1158/0008-5472.Can-06-1721  0.391
2006 Chi SL, Pizzo SV. Cell surface F1Fo ATP synthase: a new paradigm? Annals of Medicine. 38: 429-38. PMID 17008306 DOI: 10.1080/07853890600928698  0.689
2006 Mavropoulos JC, Isaacs WB, Pizzo SV, Freedland SJ. Is there a role for a low-carbohydrate ketogenic diet in the management of prostate cancer? Urology. 68: 15-8. PMID 16844447 DOI: 10.1016/J.Urology.2006.03.073  0.71
2006 Misra UK, Deedwania R, Pizzo SV. Activation and cross-talk between Akt, NF-kappaB, and unfolded protein response signaling in 1-LN prostate cancer cells consequent to ligation of cell surface-associated GRP78. The Journal of Biological Chemistry. 281: 13694-707. PMID 16543232 DOI: 10.1074/Jbc.M511694200  0.348
2006 Chi SL, Pizzo SV. Angiostatin is directly cytotoxic to tumor cells at low extracellular pH: a mechanism dependent on cell surface-associated ATP synthase. Cancer Research. 66: 875-82. PMID 16424020 DOI: 10.1158/0008-5472.Can-05-2806  0.705
2005 Mavropoulos JC, Fields TA, Pizzo SV. Chaperones and disease. The New England Journal of Medicine. 353: 2821-2; author reply. PMID 16382552 DOI: 10.1056/NEJMc052995  0.666
2005 Banbula A, Chang LS, Beyer WF, Bohra CL, Cianciolo GJ, Pizzo SV. The properties of rabbit alpha1-macroglobulin upon activation are distinct from those of rabbit and human alpha2-macroglobulins. Journal of Biochemistry. 138: 527-37. PMID 16272565 DOI: 10.1093/Jb/Mvi162  0.781
2005 Mavropoulos JC, Cuchacovich M, Llanos C, Aguillón JC, Gatica H, Pizzo SV, Gonzalez-Gronow M. Anti-tumor necrosis factor-alpha therapy augments dipeptidyl peptidase IV activity and decreases autoantibodies to GRP78/BIP and phosphoglucose isomerase in patients with rheumatoid arthritis. The Journal of Rheumatology. 32: 2116-24. PMID 16265688  0.717
2005 Misra UK, Pizzo SV. Coordinate regulation of forskolin-induced cellular proliferation in macrophages by protein kinase A/cAMP-response element-binding protein (CREB) and Epac1-Rap1 signaling: effects of silencing CREB gene expression on Akt activation. The Journal of Biological Chemistry. 280: 38276-89. PMID 16172130 DOI: 10.1074/Jbc.M507332200  0.312
2005 Hart JP, Broadwater G, Rabbani Z, Moeller BJ, Clough R, Huang D, Sempowski GA, Dewhirst M, Pizzo SV, Vujaskovic Z, Anscher MS. Cytokine profiling for prediction of symptomatic radiation-induced lung injury. International Journal of Radiation Oncology, Biology, Physics. 63: 1448-54. PMID 16115739 DOI: 10.1016/J.Ijrobp.2005.05.032  0.53
2005 Wahl ML, Kenan DJ, Gonzalez-Gronow M, Pizzo SV. Angiostatin's molecular mechanism: aspects of specificity and regulation elucidated. Journal of Cellular Biochemistry. 96: 242-61. PMID 16094651 DOI: 10.1002/Jcb.20480  0.336
2005 Misra UK, Sharma T, Pizzo SV. Ligation of cell surface-associated glucose-regulated protein 78 by receptor-recognized forms of alpha 2-macroglobulin: activation of p21-activated protein kinase-2-dependent signaling in murine peritoneal macrophages. Journal of Immunology (Baltimore, Md. : 1950). 175: 2525-33. PMID 16081825 DOI: 10.4049/Jimmunol.175.4.2525  0.373
2005 Gonzalez-Gronow M, Misra UK, Gawdi G, Pizzo SV. Association of plasminogen with dipeptidyl peptidase IV and Na+/H+ exchanger isoform NHE3 regulates invasion of human 1-LN prostate tumor cells. The Journal of Biological Chemistry. 280: 27173-8. PMID 15911629 DOI: 10.1074/Jbc.M500383200  0.334
2005 Misra UK, Deedwania R, Pizzo SV. Binding of activated alpha2-macroglobulin to its cell surface receptor GRP78 in 1-LN prostate cancer cells regulates PAK-2-dependent activation of LIMK. The Journal of Biological Chemistry. 280: 26278-86. PMID 15908432 DOI: 10.1074/Jbc.M414467200  0.387
2005 Williams EA, Ing RJ, Hart JP, Jaggers J, Kern FH, Craig DM, Pizzo SV. Soluble alpha2-macroglobulin receptor is increased in endotracheal aspirates from infants and children after cardiopulmonary bypass. The Journal of Thoracic and Cardiovascular Surgery. 129: 1098-103. PMID 15867786 DOI: 10.1016/J.Jtcvs.2004.08.020  0.608
2005 Misra UK, Gonzalez-Gronow M, Gawdi G, Pizzo SV. The role of MTJ-1 in cell surface translocation of GRP78, a receptor for alpha 2-macroglobulin-dependent signaling. Journal of Immunology (Baltimore, Md. : 1950). 174: 2092-7. PMID 15699139 DOI: 10.4049/Jimmunol.174.4.2092  0.401
2005 Gonzalez-Gronow M, Grenett HE, Gawdi G, Pizzo SV. Angiostatin directly inhibits human prostate tumor cell invasion by blocking plasminogen binding to its cellular receptor, CD26. Experimental Cell Research. 303: 22-31. PMID 15572024 DOI: 10.1016/J.Yexcr.2004.09.008  0.356
2005 Burwick NR, Wahl ML, Fang J, Zhong Z, Moser TL, Li B, Capaldi RA, Kenan DJ, Pizzo SV. An Inhibitor of the F1 subunit of ATP synthase (IF1) modulates the activity of angiostatin on the endothelial cell surface. The Journal of Biological Chemistry. 280: 1740-5. PMID 15528193 DOI: 10.1097/00002371-200411000-00030  0.32
2004 Misra UK, Pizzo SV. Activation of Akt/PDK signaling in macrophages upon binding of receptor-recognized forms of alpha2-macroglobulin to its cellular receptor: effect of silencing the CREB gene. Journal of Cellular Biochemistry. 93: 1020-32. PMID 15389876 DOI: 10.1002/Jcb.20233  0.331
2004 Berwin B, Delneste Y, Lovingood RV, Post SR, Pizzo SV. SREC-I, a type F scavenger receptor, is an endocytic receptor for calreticulin. The Journal of Biological Chemistry. 279: 51250-7. PMID 15371419 DOI: 10.1074/Jbc.M406202200  0.322
2004 Misra UK, Gonzalez-Gronow M, Gawdi G, Wang F, Pizzo SV. A novel receptor function for the heat shock protein Grp78: silencing of Grp78 gene expression attenuates alpha2M*-induced signalling. Cellular Signalling. 16: 929-38. PMID 15157672 DOI: 10.1016/J.Cellsig.2004.01.003  0.336
2004 Veitonmäki N, Cao R, Wu LH, Moser TL, Li B, Pizzo SV, Zhivotovsky B, Cao Y. Endothelial cell surface ATP synthase-triggered caspase-apoptotic pathway is essential for k1-5-induced antiangiogenesis. Cancer Research. 64: 3679-86. PMID 15150128 DOI: 10.1158/0008-5472.Can-03-1754  0.301
2004 Gonzalez-Gronow M, Hershfield MS, Arredondo-Vega FX, Pizzo SV. Cell surface adenosine deaminase binds and stimulates plasminogen activation on 1-LN human prostate cancer cells. The Journal of Biological Chemistry. 279: 20993-8. PMID 15016824 DOI: 10.1074/Jbc.M401023200  0.343
2004 Misra UK, Pizzo SV. Potentiation of signal transduction mitogenesis and cellular proliferation upon binding of receptor-recognized forms of alpha2-macroglobulin to 1-LN prostate cancer cells. Cellular Signalling. 16: 487-96. PMID 14709337 DOI: 10.1016/J.Cellsig.2003.09.010  0.351
2004 Hart JP, Gunn MD, Pizzo SV. A CD91-positive subset of CD11c+ blood dendritic cells: characterization of the APC that functions to enhance adaptive immune responses against CD91-targeted antigens. Journal of Immunology (Baltimore, Md. : 1950). 172: 70-8. PMID 14688311 DOI: 10.4049/Jimmunol.172.1.70  0.567
2004 Hart J, Rabbani Z, Pizzo S, Vujaskovic Z, Anscher M. Cytokine profiling to predict radiation-induced lung injury International Journal of Radiation Oncology*Biology*Physics. 60: S238. DOI: 10.1016/J.Ijrobp.2004.06.201  0.512
2003 Berwin B, Hart JP, Rice S, Gass C, Pizzo SV, Post SR, Nicchitta CV. Scavenger receptor-A mediates gp96/GRP94 and calreticulin internalization by antigen-presenting cells. The Embo Journal. 22: 6127-36. PMID 14609958 DOI: 10.1093/Emboj/Cdg572  0.611
2003 McLachlan JB, Hart JP, Pizzo SV, Shelburne CP, Staats HF, Gunn MD, Abraham SN. Mast cell-derived tumor necrosis factor induces hypertrophy of draining lymph nodes during infection. Nature Immunology. 4: 1199-205. PMID 14595438 DOI: 10.1038/Ni1005  0.555
2003 Fields RC, Schoenecker JG, Hart JP, Hoffman MR, Pizzo SV, Lawson JH. Protease-activated receptor-2 signaling triggers dendritic cell development. The American Journal of Pathology. 162: 1817-22. PMID 12759239 DOI: 10.1016/S0002-9440(10)64316-7  0.568
2003 Mathew S, Arandjelovic S, Beyer WF, Gonias SL, Pizzo SV. Characterization of the interaction between alpha2-macroglobulin and fibroblast growth factor-2: the role of hydrophobic interactions. The Biochemical Journal. 374: 123-9. PMID 12755687 DOI: 10.1042/Bj20021655  0.548
2003 Gonzalez-Gronow M, Kalfa T, Johnson CE, Gawdi G, Pizzo SV. The voltage-dependent anion channel is a receptor for plasminogen kringle 5 on human endothelial cells. The Journal of Biological Chemistry. 278: 27312-8. PMID 12736244 DOI: 10.1074/Jbc.M303172200  0.336
2002 Cuchacovich M, Gatica H, Vial P, Yovanovich J, Pizzo SV, Gonzalez-Gronow M. Streptokinase promotes development of dipeptidyl peptidase IV (CD26) autoantibodies after fibrinolytic therapy in myocardial infarction patients. Clinical and Diagnostic Laboratory Immunology. 9: 1253-9. PMID 12414758 DOI: 10.1128/Cdli.9.6.1253-1259.2002  0.32
2002 Misra UK, Gonzalez-Gronow M, Gawdi G, Hart JP, Johnson CE, Pizzo SV. The role of Grp 78 in alpha 2-macroglobulin-induced signal transduction. Evidence from RNA interference that the low density lipoprotein receptor-related protein is associated with, but not necessary for, GRP 78-mediated signal transduction. The Journal of Biological Chemistry. 277: 42082-7. PMID 12194978 DOI: 10.1074/Jbc.M206174200  0.65
2002 Thøgersen IB, Hammes SR, Rubenstein DS, Pizzo SV, Valnickova Z, Enghild JJ. New member of the trefoil factor family of proteins is an alpha-macroglobulin protease inhibitor. Biochimica Et Biophysica Acta. 1598: 131-9. PMID 12147353 DOI: 10.1016/S0167-4838(02)00360-6  0.565
2002 Misra UK, Akabani G, Pizzo SV. The role of cAMP-dependent signaling in receptor-recognized forms of alpha 2-macroglobulin-induced cellular proliferation. The Journal of Biological Chemistry. 277: 36509-20. PMID 12114513 DOI: 10.1074/Jbc.M203543200  0.381
2002 Gonzalez-Gronow M, Gawdi G, Pizzo SV. Tissue factor is the receptor for plasminogen type 1 on 1-LN human prostate cancer cells. Blood. 99: 4562-7. PMID 12036889 DOI: 10.1182/Blood.V99.12.4562  0.392
2002 Berwin B, Hart JP, Pizzo SV, Nicchitta CV. Cutting edge: CD91-independent cross-presentation of GRP94(gp96)-associated peptides. Journal of Immunology (Baltimore, Md. : 1950). 168: 4282-6. PMID 11970968 DOI: 10.4049/Jimmunol.168.9.4282  0.577
2002 Moser TL, Stack MS, Wahl ML, Pizzo SV. The mechanism of action of angiostatin: can you teach an old dog new tricks? Thrombosis and Haemostasis. 87: 394-401. PMID 11916069 DOI: 10.1055/S-0037-1613016  0.514
2002 Misra UK, Pizzo SV. Regulation of cytosolic phospholipase A2 activity in macrophages stimulated with receptor-recognized forms of alpha 2-macroglobulin: role in mitogenesis and cell proliferation. The Journal of Biological Chemistry. 277: 4069-78. PMID 11733496 DOI: 10.1074/Jbc.M109764200  0.417
2001 Misra UK, Pizzo SV. Receptor-associated protein binding blocks ubiquitinylation of the low density lipoprotein receptor-related protein. Archives of Biochemistry and Biophysics. 396: 106-10. PMID 11716468 DOI: 10.1006/Abbi.2001.2597  0.361
2001 Cianciolo GJ, Enghild JJ, Pizzo SV. Covalent complexes of antigen and alpha(2)-macroglobulin: evidence for dramatically-increased immunogenicity. Vaccine. 20: 554-62. PMID 11672922 DOI: 10.1016/S0264-410X(01)00361-9  0.351
2001 Misra UK, Adlakha CL, Gawdi G, McMillian MK, Pizzo SV, Laskowitz DT. Apolipoprotein E and mimetic peptide initiate a calcium-dependent signaling response in macrophages. Journal of Leukocyte Biology. 70: 677-83. PMID 11590206 DOI: 10.1189/Jlb.70.4.677  0.323
2001 Misra UK, Pizzo SV. Induction of cyclooxygenase-2 synthesis by ligation of the macrophage alpha(2)-macroglobulin signalling receptor. Cellular Signalling. 13: 801-8. PMID 11583915 DOI: 10.1016/S0898-6568(01)00202-9  0.383
2001 Bhattacharjee G, Misra UK, Gawdi G, Cianciolo G, Pizzo SV. Inducible expression of the alpha2-macroglobulin signaling receptor in response to antigenic stimulation: a study of second messenger generation. Journal of Cellular Biochemistry. 82: 260-70. PMID 11527151 DOI: 10.1002/Jcb.1152  0.623
2001 Adlakha CL, Hart JP, Pizzo SV. Kinetics of nonproteolytic incorporation of a protein ligand into thermally activated alpha 2-macroglobulin: evidence for a novel nascent state. The Journal of Biological Chemistry. 276: 41547-52. PMID 11514568 DOI: 10.1074/Jbc.M106357200  0.619
2001 Wu SM, Pizzo SV. alpha(2)-Macroglobulin from rheumatoid arthritis synovial fluid: functional analysis defines a role for oxidation in inflammation. Archives of Biochemistry and Biophysics. 391: 119-26. PMID 11414692 DOI: 10.1006/Abbi.2001.2408  0.342
2001 Moser TL, Kenan DJ, Ashley TA, Roy JA, Goodman MD, Misra UK, Cheek DJ, Pizzo SV. Endothelial cell surface F1-F0 ATP synthase is active in ATP synthesis and is inhibited by angiostatin. Proceedings of the National Academy of Sciences of the United States of America. 98: 6656-61. PMID 11381144 DOI: 10.1073/Pnas.131067798  0.331
2001 Asplin IR, Wu SM, Mathew S, Bhattacharjee G, Pizzo SV. Differential regulation of the fibroblast growth factor (FGF) family by alpha(2)-macroglobulin: evidence for selective modulation of FGF-2-induced angiogenesis. Blood. 97: 3450-7. PMID 11369636 DOI: 10.1182/Blood.V97.11.3450  0.797
2001 Misra UK, Pizzo SV. Ligation of the alpha2M* signaling receptor regulates synthesis of cytosolic phospholipase A2. Archives of Biochemistry and Biophysics. 386: 227-32. PMID 11368346 DOI: 10.1006/Abbi.2000.2199  0.317
2001 Gonzalez-Gronow M, Grenett HE, Weber MR, Gawdi G, Pizzo SV. Interaction of plasminogen with dipeptidyl peptidase IV initiates a signal transduction mechanism which regulates expression of matrix metalloproteinase-9 by prostate cancer cells. The Biochemical Journal. 355: 397-407. PMID 11284727 DOI: 10.1042/0264-6021:3550397  0.326
2001 Laskowitz DT, Thekdi AD, Thekdi SD, Han SK, Myers JK, Pizzo SV, Bennett ER. Downregulation of microglial activation by apolipoprotein E and apoE-mimetic peptides. Experimental Neurology. 167: 74-85. PMID 11161595 DOI: 10.1006/Exnr.2001.7541  0.302
2000 Asplin IR, Misra UK, Gawdi G, Gonzalez-Gronow M, Pizzo SV. Selective upregulated expression of the alpha2-macroglobulin signaling receptor in highly metastatic 1-LN prostate carcinoma cells. Archives of Biochemistry and Biophysics. 383: 135-41. PMID 11097186 DOI: 10.1006/Abbi.2000.2052  0.804
2000 Misra UK, Pizzo SV. Cytosolic phospholipase A(2) activity associated with nuclei is not inhibited by arachidonyl trifluoromethyl ketone in macrophages stimulated with receptor-recognized forms of alpha(2)-macroglobulin. Archives of Biochemistry and Biophysics. 379: 153-60. PMID 10864453 DOI: 10.1006/Abbi.2000.1878  0.385
2000 Bhattacharjee G, Asplin IR, Wu SM, Gawdi G, Pizzo SV. The conformation-dependent interaction of alpha 2-macroglobulin with vascular endothelial growth factor. A novel mechanism of alpha 2-macroglobulin/growth factor binding. The Journal of Biological Chemistry. 275: 26806-11. PMID 10862607 DOI: 10.1074/Jbc.M000156200  0.801
2000 Misra UK, Gawdi G, Pizzo SV. Potentiation of calcium levels by extracellular arachidonic acid in nuclei isolated from macrophages stimulated with receptor-recognized forms of alpha(2)-macroglobulin. Cellular Signalling. 12: 99-104. PMID 10679578 DOI: 10.1016/S0898-6568(99)00070-4  0.342
1999 Misra UK, Gawdi G, Pizzo SV. Ligation of low-density lipoprotein receptor-related protein with antibodies elevates intracellular calcium and inositol 1,4, 5-trisphosphate in macrophages. Archives of Biochemistry and Biophysics. 372: 238-47. PMID 10600161 DOI: 10.1006/Abbi.1999.1521  0.323
1999 Wu SM, Pizzo SV. Mechanism of hypochlorite-mediated inactivation of proteinase inhibition by alpha 2-macroglobulin. Biochemistry. 38: 13983-90. PMID 10529245 DOI: 10.1021/Bi991438I  0.366
1999 Misra UK, Gawdi G, Gonzalez-Gronow M, Pizzo SV. Coordinate regulation of the alpha(2)-macroglobulin signaling receptor and the low density lipoprotein receptor-related protein/alpha(2)-macroglobulin receptor by insulin. The Journal of Biological Chemistry. 274: 25785-91. PMID 10464317 DOI: 10.1074/Jbc.274.36.25785  0.384
1999 Bhattacharjee G, Grøn H, Pizzo SV. Incorporation of non-proteolytic proteins by murine alpha2-macroglobulin. Biochimica Et Biophysica Acta. 1432: 49-56. PMID 10366727 DOI: 10.1016/S0167-4838(99)00072-2  0.637
1999 Moser TL, Stack MS, Asplin I, Enghild JJ, Højrup P, Everitt L, Hubchak S, Schnaper HW, Pizzo SV. Angiostatin binds ATP synthase on the surface of human endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 96: 2811-6. PMID 10077593 DOI: 10.1073/Pnas.96.6.2811  0.81
1999 Misra UK, Pizzo SV. Upregulation of macrophage plasma membrane and nuclear phospholipase D activity on ligation of the alpha2-macroglobulin signaling receptor: involvement of heterotrimeric and monomeric G proteins. Archives of Biochemistry and Biophysics. 363: 68-80. PMID 10049500 DOI: 10.1006/Abbi.1998.1074  0.349
1998 Misra UK, Pizzo SV. Ligation of the alpha2M signalling receptor elevates the levels of p21Ras-GTP in macrophages. Cellular Signalling. 10: 441-5. PMID 9720766 DOI: 10.1016/S0898-6568(97)00171-X  0.339
1998 Misra UK, Pizzo SV. Binding of receptor-recognized forms of alpha2-macroglobulin to the alpha2-macroglobulin signaling receptor activates phosphatidylinositol 3-kinase. The Journal of Biological Chemistry. 273: 13399-402. PMID 9593670 DOI: 10.1074/Jbc.273.22.13399  0.357
1998 Grøn H, Pizzo SV. Nonproteolytic incorporation of protein ligands into human alpha 2-macroglobulin: implications for the binding mechanism of alpha 2-macroglobulin. Biochemistry. 37: 6009-14. PMID 9558338 DOI: 10.1021/Bi973027C  0.387
1998 Misra UK, Pizzo SV. Ligation of the alpha2M signaling receptor with receptor-recognized forms of alpha2-macroglobulin initiates protein and DNA synthesis in macrophages. The effect of intracellular calcium. Biochimica Et Biophysica Acta. 1401: 121-8. PMID 9459492 DOI: 10.1016/S0167-4889(97)00123-7  0.353
1998 Gonzalez-Gronow M, Weber MR, Shearin TV, Gawdi G, Pirie-Shepherd SR, Pizzo SV. Plasmin(ogen) carbohydrate chains mediate binding to dipeptidyl peptidase IV (CD 26) in rheumatoid arthritis human synovial fibroblasts Fibrinolysis and Proteolysis. 12: 366-374. DOI: 10.1016/S0268-9499(98)80395-0  0.307
1998 Gonzalez-Gronow M, Weber MR, Gawdi G, Pizzo SV. Dipeptidyl peptidase IV (CD26) is a receptor for streptokinase on rheumatoid synovial fibroblasts Fibrinolysis and Proteolysis. 12: 129-135. DOI: 10.1016/S0268-9499(98)80294-4  0.367
1997 Odom AR, Misra UK, Pizzo SV. Nickel inhibits binding of alpha2-macroglobulin-methylamine to the low-density lipoprotein receptor-related protein/alpha2-macroglobulin receptor but not the alpha2-macroglobulin signaling receptor. Biochemistry. 36: 12395-9. PMID 9376342 DOI: 10.1021/Bi970806K  0.373
1997 Shackelford RE, Alford PB, Xue Y, Thai SF, Adams DO, Pizzo S. Aspirin inhibits tumor necrosis factoralpha gene expression in murine tissue macrophages. Molecular Pharmacology. 52: 421-9. PMID 9281604 DOI: 10.1124/Mol.52.3.421  0.364
1997 Wu SM, Boyer CM, Pizzo SV. The binding of receptor-recognized alpha2-macroglobulin to the low density lipoprotein receptor-related protein and the alpha2M signaling receptor is decoupled by oxidation. The Journal of Biological Chemistry. 272: 20627-35. PMID 9252378 DOI: 10.1074/Jbc.272.33.20627  0.356
1997 Grøn H, Pike R, Potempa J, Travis J, Thøgersen IB, Enghild JJ, Pizzo SV. The potential role of alpha 2-macroglobulin in the control of cysteine proteinases (gingipains) from Porphyromonas gingivalis. Journal of Periodontal Research. 32: 61-8. PMID 9085244 DOI: 10.1111/J.1600-0765.1997.Tb01383.X  0.386
1997 Misra UK, Gawdi G, Pizzo SV. Chloroquine, quinine and quinidine inhibit calcium release from macrophage intracellular stores by blocking inositol 1,4,5-trisphosphate binding to its receptor. Journal of Cellular Biochemistry. 64: 225-32. PMID 9027583 DOI: 10.1002/(Sici)1097-4644(199702)64:2<225::Aid-Jcb6>3.0.Co;2-Z  0.331
1997 Misra UK, Gonzalez-Gronow M, Gawdi G, Pizzo SV. Up-regulation of the alpha2-macroglobulin signaling receptor on rheumatoid synovial fibroblasts. The Journal of Biological Chemistry. 272: 497-502. PMID 8995289 DOI: 10.1074/Jbc.272.1.497  0.367
1996 Bradford WD, Anthony D, Chu CT, Pizzo SV. Career characteristics of graduates of a Medical Scientist Training Program, 1970-1990. Academic Medicine : Journal of the Association of American Medical Colleges. 71: 484-7. PMID 9114867 DOI: 10.1097/00001888-199605000-00019  0.477
1996 Misra UK, Shackelford RE, Florine-Casteel K, Thai SF, Alford PB, Pizzo SV, Adams DO. Maleylated-BSA induces hydrolysis of PIP2, fluxes of Ca2+, NF-kappaB binding, and transcription of the TNF-alpha gene in murine macrophages. Journal of Leukocyte Biology. 60: 784-92. PMID 8975883 DOI: 10.1002/Jlb.60.6.784  0.373
1996 Howard GC, DeCamp DL, Misra UK, Pizzo SV. Identification of residues in α-macroglobulins involved in activation of the α2-macroglobulin signaling receptor Biochimica Et Biophysica Acta - Protein Structure and Molecular Enzymology. 1297: 111-114. PMID 8917609 DOI: 10.1016/S0167-4838(96)00135-5  0.375
1996 Grøn H, Thøgersen IB, Enghild JJ, Pizzo SV. Structural and functional analysis of the spontaneous re-formation of the thiol ester bond in human α2-macroglobulin, rat α1-inhibitor-3 and chemically modified derivatives Biochemical Journal. 318: 539-545. PMID 8809044 DOI: 10.1042/Bj3180539  0.367
1996 Howard GC, Roberts BC, Epstein DL, Pizzo SV. Characterization of α2-macroglobulin binding to human trabecular meshwork cells: Presence of the α2-macroglobulin signaling receptor Archives of Biochemistry and Biophysics. 333: 19-26. PMID 8806749 DOI: 10.1006/Abbi.1996.0359  0.412
1996 Moser TL, Pizzo SV, Bafetti LM, Fishman DA, Stack MS. Evidence for preferential adhesion of ovarian epithelial carcinoma cells to type I collagen mediated by the alpha2beta1 integrin. International Journal of Cancer. Journal International Du Cancer. 67: 695-701. PMID 8782661 DOI: 10.1002/(Sici)1097-0215(19960904)67:5<695::Aid-Ijc18>3.0.Co;2-4  0.554
1996 Misra UK, Gawdi G, Pizzo SV. Binding Of Rat Alpha 1-Inhibitor-3-Methylamine To The Alpha 2-Macroglobulin Signaling Receptor Induces Second Messengers Journal of Cellular Biochemistry. 61: 61-71. PMID 8726356 DOI: 10.1002/(Sici)1097-4644(19960401)61:1<61::Aid-Jcb8>3.0.Co;2-0  0.39
1996 Misra UK, Pizzo SV. Ligation of the α2-macroglobulin signaling receptor on macrophages induces synthesis of platelet activating factor Journal of Cellular Biochemistry. 61: 39-47. PMID 8726354 DOI: 10.1002/(Sici)1097-4644(19960401)61:1<39::Aid-Jcb6>3.0.Co;2-3  0.397
1996 Young TN, Rodriguez GC, Rinehart AR, Bast RC, Pizzo SV, Stack MS. Characterization of gelatinases linked to extracellular matrix invasion in ovarian adenocarcinoma: purification of matrix metalloproteinase 2. Gynecologic Oncology. 62: 89-99. PMID 8690299 DOI: 10.1006/Gyno.1996.0195  0.525
1996 Howard GC, Yamaguchi Y, Misra UK, Gawdi G, Nelsen A, DeCamp DL, Pizzo SV. Selective mutations in cloned and expressed α-macroglobulin receptor binding fragment alter binding to either the α2-macroglobulin signaling receptor or the low density lipoprotein receptor-related protein/α2-macroglobulin receptor Journal of Biological Chemistry. 271: 14105-14111. PMID 8662881 DOI: 10.1074/Jbc.271.24.14105  0.339
1996 Valnickova Z, Thogersen IB, Christensen S, Chu CT, Pizzo SV, Enghild JJ. Activated human plasma carboxypeptidase B is retained in the blood by binding to alpha2-macroglobulin and pregnancy zone protein. The Journal of Biological Chemistry. 271: 12937-43. PMID 8662763 DOI: 10.1074/Jbc.271.22.12937  0.586
1996 Howard GC, Misra UK, DeCamp DL, Pizzo SV. Altered interaction of cis-dichlorodiammineplatinum(II)-modified α2-macroglobulin (α2M) with the low density lipoprotein receptor-related protein/ α2M receptor but not the α2M signaling receptor. Evidence for interference with receptor dissociation and recycling Journal of Clinical Investigation. 97: 1193-1203. PMID 8636430 DOI: 10.1172/Jci118533  0.375
1996 Wu SM, Pizzo SV. Low-density lipoprotein receptor-related protein/α2-macroglobulin receptor on murine peritoneal macrophages mediates the binding and catabolism of low-density lipoprotein Archives of Biochemistry and Biophysics. 326: 39-47. PMID 8579370 DOI: 10.1006/Abbi.1996.0044  0.399
1996 Serrano RL, Rodriguez P, Pizzo SV, Gonzalez-Gronow M. ATP-regulated activity of the plasmin-streptokinase complex: A novel mechanism involving phosphorylation of streptokinase Biochemical Journal. 313: 171-177. PMID 8546680 DOI: 10.1042/Bj3130171  0.342
1995 Edelberg JM, Pizzo SV. Lipoprotein (a) in the regulation of fibrinolysis Journal of Atherosclerosis and Thrombosis. 2: S5-7. PMID 9225222 DOI: 10.5551/Jat1994.2.Supplement1_S5  0.613
1995 Webb DJ, Hussaini IM, Weaver AM, Atkins TL, Chu CT, Pizzo SV, Owens GK, Gonias SL. Activated alpha 2-macroglobulin promotes mitogenesis in rat vascular smooth muscle cells by a mechanism that is independent of growth-factor-carrier activity. European Journal of Biochemistry / Febs. 234: 714-22. PMID 8575427 DOI: 10.1111/J.1432-1033.1995.714_A.X  0.607
1995 Edelberg JM, Sane DC, Pizzo SV. Vascular regulation of plasminogen activator inhibitor-1 activity. Seminars in Thrombosis and Hemostasis. 20: 319-23. PMID 7899861 DOI: 10.1055/S-2007-1001920  0.601
1995 Pirie-Shepherd SR, Jett EA, Andon NL, Pizzo SV. Sialic acid content of plasminogen 2 glycoforms as a regulator of fibrinolytic activity: Isolation, carbohydrate analysis, and kinetic characterization of six glycoforms of plasminogen 2 Journal of Biological Chemistry. 270: 5877-5881. PMID 7890718 DOI: 10.1074/Jbc.270.11.5877  0.354
1995 Shackelford RE, Misra UK, Florine-Casteel K, Thai SF, Pizzo SV, Adams DO. Oxidized low density lipoprotein suppresses activation of NFκB in macrophages via a pertussis toxin-sensitive signaling mechanism Journal of Biological Chemistry. 270: 3475-3478. PMID 7876078 DOI: 10.1074/Jbc.270.8.3475  0.347
1995 Young TN, Pizzo SV, Stack MS. A plasma membrane-associated component of ovarian adenocarcinoma cells enhances the catalytic efficiency of matrix metalloproteinase-2. The Journal of Biological Chemistry. 270: 999-1002. PMID 7836420 DOI: 10.1074/Jbc.270.3.999  0.532
1995 Misra UK, Gawdi G, Pizzo SV. Ligation of the α2-macroglobulin signalling receptor on macrophages induces protein phosphorylatian and an increase in cytosolic pH Biochemical Journal. 309: 151-158. PMID 7542445 DOI: 10.1042/Bj3090151  0.394
1995 Moser TL, Enghild JJ, Pizzo SV, Stack MS. Specific binding of urinary-type plasminogen activator (u-PA) to vitronectin and its role in mediating u-PA-dependent adhesion of U937 cells. The Biochemical Journal. 307: 867-73. PMID 7537960 DOI: 10.1042/Bj3070867  0.56
1995 Falkenberg C, Allhorn M, Thøgersen IB, Valnickova Z, Pizzo SV, Salvesen G, Åkerström B, Enghild JJ. α1-Microglobulin destroys the proteinase inhibitory activity of α1-inhibitor-3 by complex formation Journal of Biological Chemistry. 270: 4478-4483. PMID 7533162 DOI: 10.1074/Jbc.270.9.4478  0.563
1994 Edelberg J, Pizzo SV. Lipoprotein (a) regulates plasmin generation and inhibition. Chemistry and Physics of Lipids. 363-8. PMID 8187236 DOI: 10.1016/0009-3084(94)90158-9  0.635
1994 Young TN, Rodriguez GC, Moser TL, Bast RC, Pizzo SV, Stack MS. Coordinate expression of urinary-type plasminogen activator and its receptor accompanies malignant transformation of the ovarian surface epithelium. American Journal of Obstetrics and Gynecology. 170: 1285-96. PMID 8178854 DOI: 10.1016/S0002-9378(94)70143-1  0.551
1994 Stack MS, Pizzo SV. The effect of substituted laminin A chain-derived peptides on the conformation and activation kinetics of plasminogen. Archives of Biochemistry and Biophysics. 309: 117-22. PMID 8117101 DOI: 10.1006/Abbi.1994.1093  0.542
1994 Moser TL, Young TN, Rodriguez GC, Pizzo SV, Bast RC, Stack MS. Secretion of extracellular matrix-degrading proteinases is increased in epithelial ovarian carcinoma. International Journal of Cancer. Journal International Du Cancer. 56: 552-9. PMID 8112891 DOI: 10.1002/Ijc.2910560415  0.551
1994 Stack MS, Rinehart AR, Pizzo SV. Comparison of plasminogen binding and activation on extracellular matrices produced by vascular smooth muscle and endothelial cells. European Journal of Biochemistry / Febs. 226: 937-43. PMID 7813484 DOI: 10.1111/J.1432-1033.1994.00937.X  0.566
1994 Chu CT, Pizzo SV. alpha 2-Macroglobulin, complement, and biologic defense: antigens, growth factors, microbial proteases, and receptor ligation. Laboratory Investigation; a Journal of Technical Methods and Pathology. 71: 792-812. PMID 7528831  0.54
1994 Chu CT, Howard GC, Misra UK, Pizzo SV. Alpha 2-macroglobulin: a sensor for proteolysis. Annals of the New York Academy of Sciences. 737: 291-307. PMID 7524403 DOI: 10.1111/J.1749-6632.1994.Tb44319.X  0.541
1994 Misra UK, Chu CT, Gawdi G, Pizzo SV. The relationship between low density lipoprotein-related protein/alpha 2-macroglobulin (alpha 2M) receptors and the newly described alpha 2M signaling receptor. The Journal of Biological Chemistry. 269: 18303-6. PMID 7518427  0.562
1994 Misra UK, Chu CT, Gawdi G, Pizzo SV. Evidence for a second alpha 2-macroglobulin receptor. The Journal of Biological Chemistry. 269: 12541-7. PMID 7513689  0.569
1994 Chu CT, Oury TD, Enghild JJ, Pizzo SV. Adjuvant-free in vivo targeting. Antigen delivery by alpha 2-macroglobulin enhances antibody formation. Journal of Immunology (Baltimore, Md. : 1950). 152: 1538-45. PMID 7509826  0.559
1994 Youna TN, Moser TL, Rodriguez GC, Bast RC, Pizzo SV, Stack M. Regulation of ovarian carcinoma-associaited proteinases: Cell surface-mediated proteolysis by plasma membrane localized matrix metalloproteinase-2 and urinary-type plasminogen activator Fibrinolysis. 8: 56. DOI: 10.1016/0268-9499(94)90440-5  0.525
1994 Moser TL, Enghild JJ, Pizzo SV, Sharon Stack M. Interaction of urinary-type plasminogen activator with extracellular matrix proteins: Specific binding to vitronectin Fibrinolysis. 8: 34. DOI: 10.1016/0268-9499(94)90378-6  0.307
1993 Stack MS, Gray RD, Pizzo SV. Modulation of murine B16F10 melanoma plasminogen activator production by a synthetic peptide derived from the laminin A chain. Cancer Research. 53: 1998-2004. PMID 8481902  0.622
1993 Stack MS, Pizzo SV. Modulation of tissue plasminogen activator-catalyzed plasminogen activation by synthetic peptides derived from the amino-terminal heparin binding domain of fibronectin. The Journal of Biological Chemistry. 268: 18924-8. PMID 8360182  0.508
1993 Moser TL, Enghild JJ, Pizzo SV, Stack MS. The extracellular matrix proteins laminin and fibronectin contain binding domains for human plasminogen and tissue plasminogen activator. The Journal of Biological Chemistry. 268: 18917-23. PMID 8360181  0.517
1993 Edelberg JM, Lee YJ, Young TN, Pizzo SV. Lipoprotein (a): Purification and kinetic analysis Methods in Enzymology. 223: 272-288. PMID 8271958 DOI: 10.1016/0076-6879(93)23051-N  0.635
1993 Enghild JJ, Valnickova Z, Thøgersen IB, Pizzo SV, Salvesen G. An examination of the inhibitory mechanism of serpins by analysing the interaction of trypsin and chymotrypsin with alpha 2-antiplasmin. The Biochemical Journal. 933-8. PMID 7683878 DOI: 10.1042/Bj2910933  0.54
1993 Gonias SL, Marshall LB, Figler NL, Hussaini IM, Moncino MD, Pizzo SV. Electron microscopy studies of alpha 2-macroglobulin subunit association after limited reduction with dithiothreitol. Archives of Biochemistry and Biophysics. 302: 42-8. PMID 7682394 DOI: 10.1006/Abbi.1993.1178  0.358
1993 Misra UK, Chu CT, Rubenstein DS, Gawdi G, Pizzo SV. Receptor-recognized alpha 2-macroglobulin-methylamine elevates intracellular calcium, inositol phosphates and cyclic AMP in murine peritoneal macrophages. The Biochemical Journal. 290: 885-91. PMID 7681282 DOI: 10.1042/Bj2900885  0.607
1993 Gonzalez-Gronow M, Enghild JJ, Pizzo SV. Streptokinase and human fibronectin share a common epitope: implications for regulation of fibrinolysis and rheumatoid arthritis. Biochimica Et Biophysica Acta. 1180: 283-8. PMID 7678505 DOI: 10.1016/0925-4439(93)90051-2  0.304
1993 Chu CT, Pizzo SV. Receptor-mediated antigen delivery into macrophages. Complexing antigen to alpha 2-macroglobulin enhances presentation to T cells. Journal of Immunology (Baltimore, Md. : 1950). 150: 48-58. PMID 7678035  0.56
1992 Edelberg JM, Pizzo SV. Lipoprotein(a) inhibits plasminogen activation in a template-dependent manner. Blood Coagulation & Fibrinolysis : An International Journal in Haemostasis and Thrombosis. 2: 759-64. PMID 1839224 DOI: 10.1097/00001721-199112000-00010  0.6
1992 Stack MS, Pizzo SV, Gonzalez-Gronow M. Effect of desialylation on the biological properties of human plasminogen. The Biochemical Journal. 284: 81-6. PMID 1599413 DOI: 10.1042/Bj2840081  0.572
1992 Stack MS, Moser TL, Pizzo SV. Binding of human plasminogen to basement-membrane (type IV) collagen. The Biochemical Journal. 284: 103-8. PMID 1599390 DOI: 10.1042/Bj2840103  0.581
1992 Edelberg J, Pizzo SV. Why is lipoprotein(a) relevant to thrombosis? The American Journal of Clinical Nutrition. 56: 791S-792S. PMID 1414982 DOI: 10.1093/Ajcn/56.4.791S  0.57
1992 Young TN, Edelberg JM, Stack S, Pizzo SV. Ionic modulation of the effects of heparin on plasminogen activation by tissue plasminogen activator: The effects of ionic strength, divalent cations, and chloride Archives of Biochemistry and Biophysics. 296: 530-538. PMID 1385938 DOI: 10.1016/0003-9861(92)90607-X  0.623
1992 Salvesen G, Quan LT, Enghild JJ, Snipas S, Fey GH, Pizzo SV. Expression of a functional alpha-macroglobulin receptor binding domain in Escherichia coli. Febs Letters. 313: 198-202. PMID 1385222 DOI: 10.1016/0014-5793(92)81443-P  0.573
1992 Edelberg JM, Pizzo SV. Lipoprotein (a) promotes plasmin inhibition by alpha 2-antiplasmin. The Biochemical Journal. 79-84. PMID 1381585 DOI: 10.1042/Bj2860079  0.671
1992 Thøgersen IB, Salvesen G, Brucato FH, Pizzo SV, Enghild JJ. Purification and characterization of an alpha-macroglobulin proteinase inhibitor from the mollusc Octopus vulgaris. The Biochemical Journal. 521-7. PMID 1379044 DOI: 10.1042/Bj2850521  0.583
1992 Edelberg J, Pizzo S. Lipoprotein(A) regulates the rate of plasmin generation and inhibition Thrombosis Research. 65: S95. DOI: 10.1016/0049-3848(92)90503-3  0.582
1991 Edelberg JM, Conrad HE, Pizzo SV. Heparin oligosaccharides enhance tissue-type plasminogen activator: a correlation between oligosaccharide length and stimulation of plasminogen activation. Biochemistry. 30: 10999-1003. PMID 1932024 DOI: 10.1021/bi00109a027  0.578
1991 Stack S, Gonzalez-Gronow M, Pizzo SV. The effect of divalent cations on the conformation and function of human plasminogen. Archives of Biochemistry and Biophysics. 284: 58-62. PMID 1899177 DOI: 10.1016/0003-9861(91)90263-I  0.315
1991 Stack S, Gray RD, Pizzo SV. Modulation of plasminogen activation and type IV collagenase activity by a synthetic peptide derived from the laminin a chain Biochemistry. 30: 2073-2077. PMID 1847824 DOI: 10.1021/Bi00222A011  0.523
1991 Edelberg JM, Weissler M, Pizzo SV. Kinetic analysis of the effects of glycosaminoglycans and lipoproteins on urokinase-mediated plasminogen activation. The Biochemical Journal. 785-91. PMID 1829607 DOI: 10.1042/Bj2760785  0.627
1991 Chu CT, Pizzo SV. Interactions between cytokines and alpha 2-macroglobulin. Immunology Today. 12: 249. PMID 1716108 DOI: 10.1016/0167-5699(91)90043-S  0.517
1991 Uhing RJ, Martenson CH, Rubenstein DS, Hollenbach PW, Pizzo SV. The exposure of murine macrophages to alpha 2-macroglobulin 'fast' forms results in the rapid secretion of eicosanoids. Biochimica Et Biophysica Acta. 1093: 115-20. PMID 1713784 DOI: 10.1016/0167-4889(91)90111-A  0.364
1991 Mast AE, Enghild JJ, Pizzo SV, Salvesen G. Analysis of the plasma elimination kinetics and conformational stabilities of native, proteinase-complexed, and reactive site cleaved serpins: Comparison of α1-proteinase inhibitor, α1-antichymotrypsin, antithrombin III, α2-antiplasmin, angiotensinogen, and ovalbumin Biochemistry. 30: 1723-1730. PMID 1704258 DOI: 10.1021/Bi00220A039  0.52
1991 Chu CT, Rubenstein DS, Enghild JJ, Pizzo SV. Mechanism of insulin incorporation into alpha 2-macroglobulin: implications for the study of peptide and growth factor binding. Biochemistry. 30: 1551-60. PMID 1704257 DOI: 10.1021/Bi00220A016  0.596
1991 Moncino MD, Roche PA, Pizzo SV. Characterization of human alpha 2-macroglobulin monomers obtained by reduction with dithiothreitol. Biochemistry. 30: 1545-51. PMID 1704256 DOI: 10.1021/Bi00220A015  0.358
1991 Enghild JJ, Thøgersen IB, Salvesen G, Fey GH, Figler NL, Gonias SL, Pizzo SV. Alpha-macroglobulin from Limulus polyphemus exhibits proteinase inhibitory activity and participates in a hemolytic system. Biochemistry. 29: 10070-80. PMID 1703001 DOI: 10.1021/Bi00495A009  0.572
1991 Gonzalez-Gronow M, Stack S, Pizzo SV. Plasmin binding to the plasminogen receptor enhances catalytic efficiency and activates the receptor for subsequent ligand binding. Archives of Biochemistry and Biophysics. 286: 625-8. PMID 1654795 DOI: 10.1016/0003-9861(91)90090-6  0.345
1991 Edelberg J, Pizzo S. Lipoprotein (a): The link between impaired fibrinolysis and atherosclerosis Fibrinolysis. 5: 135-143. DOI: 10.1016/0268-9499(91)90015-V  0.568
1990 Roche PA, Moncino MD, Pizzo SV. Independent analysis of bait region cleavage dependent and thiolester bond cleavage dependent conformational changes by cross-linking of alpha 2-macroglobulin with cis-dichlorodiammineplatinum(II) and dithiobis(succinimidyl propionate). Biochemistry. 28: 7629-36. PMID 2482066 DOI: 10.1021/Bi00445A019  0.363
1990 Edelberg JM, Enghild JJ, Pizzo SV, Gonzalez-Gronow M. Neonatal plasminogen displays altered cell surface binding and activation kinetics. Correlation with increased glycosylation of the protein. The Journal of Clinical Investigation. 86: 107-12. PMID 2365810 DOI: 10.1172/Jci114671  0.608
1990 Gonzalez-Gronow M, Grenett HE, Fuller GM, Pizzo SV. The role of carbohydrate in the function of human plasminogen: comparison of the protein obtained from molecular cloning and expression in Escherichia coli and COS cells. Biochimica Et Biophysica Acta. 1039: 269-76. PMID 2198941 DOI: 10.1016/0167-4838(90)90259-I  0.317
1990 Pizzo SV, Friedberg RC, Sze P, Winant R, Hudson D, Lazar JM, Johnson PH. Recombinant hirudin displaces human factor Xa from its endothelial binding sites. Thrombosis Research. 57: 803-6. PMID 2160134 DOI: 10.1016/0049-3848(90)90037-D  0.304
1990 Edelberg JM, Pizzo SV. Kinetic analysis of the effects of heparin and lipoproteins on tissue plasminogen activator mediated plasminogen activation. Biochemistry. 29: 5906-11. PMID 2143417 DOI: 10.1021/Bi00477A004  0.633
1990 Edelberg JM, Gonzalez-Gronow M, Pizzo SV. Lipoprotein(a) inhibition of plasminogen activation by tissue-type plasminogen activator. Thrombosis Research. 57: 155-62. PMID 2137266 DOI: 10.1016/0049-3848(90)90203-O  0.617
1990 Stack S, Gonzalez-Gronow M, Pizzo SV. Regulation of plasminogen activation by components of the extracellular matrix. Biochemistry. 29: 4966-70. PMID 2114170 DOI: 10.1021/Bi00472A029  0.322
1990 Roche PA, Hoffman MR, Pizzo SV. Effect of interferon-gamma and human alpha 2-macroglobulin on peritoneal macrophage morphology and Ia antigen expression. Biochimica Et Biophysica Acta. 1051: 166-73. PMID 1690028 DOI: 10.1016/0167-4889(90)90189-K  0.37
1989 Pizzo SV. Serpin receptor 1: a hepatic receptor that mediates the clearance of antithrombin III-proteinase complexes. The American Journal of Medicine. 87: 10S-14S. PMID 2552799 DOI: 10.1016/0002-9343(89)80524-8  0.392
1989 Gonzalez-Gronow M, Edelberg JM, Pizzo SV. Further characterization of the cellular plasminogen binding site: evidence that plasminogen 2 and lipoprotein a compete for the same site. Biochemistry. 28: 2374-7. PMID 2543441 DOI: 10.1021/Bi00432A005  0.646
1989 Edelberg JM, Gonzalez-Gronow M, Pizzo SV. Lipoprotein a inhibits streptokinase-mediated activation of human plasminogen. Biochemistry. 28: 2370-4. PMID 2525048 DOI: 10.1021/Bi00432A004  0.611
1989 Sane DC, Pizzo SV, Greenberg CS. Elevated urokinase-type plasminogen activator level and bleeding in amyloidosis: case report and literature review. American Journal of Hematology. 31: 53-7. PMID 2495717 DOI: 10.1002/Ajh.2830310111  0.323
1989 Enghild JJ, Thøgersen IB, Roche PA, Pizzo SV. A conserved region in alpha-macroglobulins participates in binding to the mammalian alpha-macroglobulin receptor. Biochemistry. 28: 1406-12. PMID 2469470 DOI: 10.1021/Bi00429A069  0.378
1989 Hoffman M, Pizzo SV, Weinberg JB. Alpha 2 macroglobulin-proteinase complexes stimulate prostaglandin E2 synthesis by peritoneal macrophages. Agents and Actions. 25: 360-7. PMID 2464277 DOI: 10.1007/Bf01965043  0.372
1989 Pratt CW, Swaim MW, Pizzo SV. Inflammatory cells degrade inter-alpha inhibitor to liberate urinary proteinase inhibitors. Journal of Leukocyte Biology. 45: 1-9. PMID 2463321 DOI: 10.1002/Jlb.45.1.1  0.383
1989 Roche PA, Salvesen GS, Pizzo SV. Symmetry of the inhibitory unit of human alpha 2-macroglobulin. Biochemistry. 27: 7876-81. PMID 2462911 DOI: 10.1021/Bi00420A044  0.555
1989 Roche PA, Pizzo SV. Analysis of thiolester bond cleavage-dependent conformational changes in binary alpha 2-macroglobulin-proteinase complexes. Archives of Biochemistry and Biophysics. 267: 285-93. PMID 2461679 DOI: 10.1016/0003-9861(88)90034-3  0.36
1988 Pizzo SV, Mast AE, Feldman SR, Salvesen G. In vivo catabolism of α1-antichymotrypsin is mediated by the Serpin receptor which binds α1-proteinase inhibitor, antithrombin III and heparin cofactor II Bba - General Subjects. 967: 158-162. PMID 3263884 DOI: 10.1016/0304-4165(88)90005-0  0.493
1988 Pratt CW, Church FC, Pizzo SV. In vivo catabolism of heparin cofactor II and its complex with thrombin: evidence for a common receptor-mediated clearance pathway for three serine proteinase inhibitors. Archives of Biochemistry and Biophysics. 262: 111-7. PMID 3258496 DOI: 10.1016/0003-9861(88)90173-7  0.353
1988 Swaim MW, Pizzo SV. Modification of the tandem reactive centres of human inter-alpha-trypsin inhibitor with butanedione and cis-dichlorodiammineplatinum(II). The Biochemical Journal. 254: 171-8. PMID 2460086 DOI: 10.1042/Bj2540171  0.365
1988 Pizzo SV, Swaim MW, Roche PA, Gonias SL. Selectivity and stereospecificity of the reactions of dichlorodiammineplatinum(II) with three purified plasma proteins. Journal of Inorganic Biochemistry. 33: 67-76. PMID 2454291 DOI: 10.1016/0162-0134(88)80035-7  0.34
1988 Roche PA, Jensen PE, Pizzo SV. Intersubunit cross-linking by cis-dichlorodiammineplatinum(II) stabilizes an alpha 2-macroglobulin "nascent" state: evidence that thiol ester bond cleavage correlates with receptor recognition site exposure. Biochemistry. 27: 759-64. PMID 2450578 DOI: 10.1021/Bi00402A040  0.356
1988 Friedberg R, Hagen P, Pizzo S. The role of endothelium in factor Xa regulation: the effect of plasma proteinase inhibitors and hirudin Blood. 71: 1321-1328. DOI: 10.1182/Blood.V71.5.1321.1321  0.354
1987 Pizzo SV, Roche PA, Feldman SR, Gonias SL. Further characterization of the platinum-reactive component of the alpha 2-macroglobulin-receptor recognition site. The Biochemical Journal. 238: 217-25. PMID 3026342 DOI: 10.1042/Bj2380217  0.382
1987 Pratt CW, Roche PA, Pizzo SV. The role of inter-alpha-trypsin inhibitor and other proteinase inhibitors in the plasma clearance of neutrophil elastase and plasmin. Archives of Biochemistry and Biophysics. 258: 591-9. PMID 2445291 DOI: 10.1016/0003-9861(87)90381-X  0.364
1987 Pratt CW, Pizzo SV. Mechanism of action of inter-alpha-trypsin inhibitor. Biochemistry. 26: 2855-63. PMID 2440471 DOI: 10.1021/Bi00384A029  0.365
1987 Roche PA, Pizzo SV. The role of histidyl residues in zinc-induced precipitation of alpha 2-macroglobulin-proteinase complexes. Archives of Biochemistry and Biophysics. 256: 265-72. PMID 2440383 DOI: 10.1016/0003-9861(87)90445-0  0.361
1987 Roche PA, Pizzo SV. Characterization of alpha 2-macroglobulin-plasmin complexes: complete subunit cleavage alters receptor recognition in vivo and in vitro. Biochemistry. 26: 486-91. PMID 2435319 DOI: 10.1021/Bi00376A021  0.4
1987 Pizzo SV, Rajagopalan S, Roche PA, Fuchs HE, Feldman SR, Gonias SL. Specificity of alpha 2-macroglobulin covalent cross-linking for the active domain of proteinases. Biological Chemistry Hoppe-Seyler. 367: 1177-82. PMID 2434119 DOI: 10.1515/Bchm3.1986.367.2.1177  0.381
1987 Turner AD, Pizzo SV, Rozakis GW, Porter NA. Photochemical activation of acylated .alpha.-thrombin Journal of the American Chemical Society. 109: 1274-1275. DOI: 10.1021/Ja00238A062  0.359
1986 Hoffman M, Fuchs HE, Pizzo SV. The macrophage-mediated regulation of hepatocyte synthesis of antithrombin III and alpha 1-proteinase inhibitor. Thrombosis Research. 41: 707-15. PMID 3485835 DOI: 10.1016/0049-3848(86)90368-3  0.362
1986 Lehrman MA, Pizzo SV, Imber MJ, Hill RL. The binding of fucose-containing glycoproteins by hepatic lectins. Re-examination of the clearance from blood and the binding to membrane receptors and pure lectins. The Journal of Biological Chemistry. 261: 7412-8. PMID 3011783  0.467
1986 Lee YS, Matthews TJ, Pizzo S, Abernethy JL, Bigner DD. Partial purification and characterization of a murine glioma-associated antigen defined by syngeneic rat monoclonal antibodies Journal of Neuroimmunology. 13: 203-216. PMID 2430998 DOI: 10.1016/0165-5728(86)90065-2  0.464
1986 Feldman SR, Pizzo SV. A three-dimensional model of a unique proteinase inhibitor: alpha 2-macroglobulin. Seminars in Thrombosis and Hemostasis. 12: 223-5. PMID 2430335 DOI: 10.1055/S-2007-1003556  0.347
1986 Gonias SL, Roche PA, Pizzo SV. Purification and characterization of human alpha 2-macroglobulin conformational variants by non-ideal high performance size-exclusion chromatography. The Biochemical Journal. 235: 559-67. PMID 2427074 DOI: 10.1042/Bj2350559  0.345
1986 Pratt CW, Pizzo SV. In vivo metabolism of inter-alpha-trypsin inhibitor and its proteinase complexes: evidence for proteinase transfer to alpha 2-macroglobulin and alpha 1-proteinase inhibitor. Archives of Biochemistry and Biophysics. 248: 587-96. PMID 2427028 DOI: 10.1016/0003-9861(86)90512-6  0.364
1986 Feldman SR, Pizzo SV. Purification and characterization of a "half-molecule" alpha 2-macroglobulin from the southern grass frog: absence of binding to the mammalian alpha 2-macroglobulin receptor. Biochemistry. 25: 721-7. PMID 2420357 DOI: 10.1021/Bi00351A032  0.378
1986 Ney KA, Gidwitz S, Pizzo SV. Binding and endocytosis of alpha 2-macroglobulin-plasmin complexes. Biochemistry. 24: 4586-92. PMID 2415157 DOI: 10.1021/Bi00338A016  0.366
1985 Pratt CW, Pizzo SV. The effect of zinc and other divalent cations on the structure and function of human alpha 2-macroglobulin. Biochimica Et Biophysica Acta. 791: 123-30. PMID 6210110 DOI: 10.1016/0167-4838(84)90002-5  0.389
1985 Strickland DK, Steiner JP, Feldman SR, Pizzo SV. Fluorescent probes as a measure of conformational alterations induced by nucleophilic modification and proteolysis of bovine alpha 2-macroglobulin. Biochemistry. 23: 6679-85. PMID 6085010 DOI: 10.1021/Bi00321A061  0.303
1985 Bourdon MA, Matthews TJ, Pizzo SV, Bigner DD. Immunochemical and biochemical characterization of a glioma-associated extracellular matrix glycoprotein Journal of Cellular Biochemistry. 28: 183-195. PMID 4066774 DOI: 10.1002/Jcb.240280302  0.48
1985 Rajagopalan S, Gonias SL, Pizzo SV. A nonantigenic covalent streptokinase-polyethylene glycol complex with plasminogen activator function. The Journal of Clinical Investigation. 75: 413-9. PMID 3156148 DOI: 10.1172/Jci111715  0.336
1985 Feldman SR, Rosenberg MR, Ney KA, Michalopoulos G, Pizzo SV. Binding of alpha 2-macroglobulin to hepatocytes: mechanism of in vivo clearance. Biochemical and Biophysical Research Communications. 128: 795-802. PMID 2581569 DOI: 10.1016/0006-291X(85)90117-2  0.358
1985 Ney KA, Pasqua JJ, Colley KJ, Guthrow CE, Pizzo SV. In vitro preparation of nonenzymatically glucosylated human transferrin,α2-macroglobulin, and fibrinogen with preservation of function Diabetes. 34: 462-470. PMID 2580749 DOI: 10.2337/Diab.34.5.462  0.31
1985 Feldman SR, Gonias SL, Pizzo SV. Model of alpha 2-macroglobulin structure and function. Proceedings of the National Academy of Sciences of the United States of America. 82: 5700-4. PMID 2412223 DOI: 10.1073/Pnas.82.17.5700  0.326
1985 Feldman SR, Pizzo SV. Purification and characterization of frog alpha-macroglobulin: receptor recognition of an amphibian glycoprotein. Biochemistry. 24: 2569-75. PMID 2410015 DOI: 10.1021/Bi00331A026  0.386
1984 Weinberg JB, Hobbs MM, Pizzo SV. Microassay for the photometric quantitation of cell-associated plasminogen activator using a chromogenic tripeptide substrate. Journal of Immunological Methods. 75: 289-94. PMID 6596319 DOI: 10.1016/0022-1759(84)90112-1  0.333
1984 Key KA, Oakley AC, Pizzo SV. Effects of pimozide and penfluridol on the binding and endocytosis of alpha 2-macroglobulin-CH3NH2 by mouse peritoneal macrophages. Biochemical Pharmacology. 33: 3712-4. PMID 6210087 DOI: 10.1016/0006-2952(84)90162-X  0.377
1984 Feldman SR, Pizzo SV. Comparison of the binding of chicken alpha-macroglobulin and ovomacroglobulin to the mammalian alpha 2-macroglobulin receptor. Archives of Biochemistry and Biophysics. 235: 267-75. PMID 6208849 DOI: 10.1016/0003-9861(84)90275-3  0.392
1984 Feldman SR, Pizzo SV. Circular dichroic spectroscopy of non-human alpha-macroglobulins. Biochemical and Biophysical Research Communications. 123: 771-7. PMID 6207818 DOI: 10.1016/0006-291X(84)90296-1  0.346
1984 Gonias SL, Feldman SR, Pratt CW, Pizzo SV. Conformation-specific precipitation of human alpha 2-macroglobulin by divalent zinc or calf thymus histone H3. Archives of Biochemistry and Biophysics. 233: 462-8. PMID 6207774 DOI: 10.1016/0003-9861(84)90468-5  0.339
1984 Ney KA, Gidwitz S, Pizzo SV. Changes in the binding of "fast"-form alpha 2-macroglobulin to 3T3-L1 cells after differentiation to adipocytes. Biochemistry. 23: 3395-403. PMID 6205689 DOI: 10.1021/Bi00310A003  0.405
1984 Cummings HS, Pizzo SV, Strickland DK, Castellino FJ. Effect of methylamine and plasmin on the conformation of human alpha 2-macroglobulin as revealed by differential scanning calorimetric analysis. Biophysical Journal. 45: 721-4. PMID 6202335 DOI: 10.1016/S0006-3495(84)84214-9  0.509
1984 Gonias SL, Pizzo SV. Chemical and structural modifications of alpha 2-macroglobulin: effects on receptor binding and endocytosis studied in an in vivo model. Annals of the New York Academy of Sciences. 421: 457-71. PMID 6202219 DOI: 10.1111/J.1749-6632.1983.Tb18139.X  0.365
1984 Gonias SL, Pizzo SV. Reaction of human alpha 2-macroglobulin half-molecules with plasmin as a probe of protease binding site structure. Biochemistry. 22: 4933-40. PMID 6196052 DOI: 10.1021/Bi00290A009  0.369
1984 Bourdon MA, Matthews TJ, Pizzo SV, Bigner DD. 24 IMMUNOCHEMICAL AND BIOCHEMICAL ANALYSIS OF THE HUMAN GLIOMA EXTRACELLULAR MATRIX GLYCOPROTEIN (GMEM) Journal of Neuropathology and Experimental Neurology. 43: 301. DOI: 10.1097/00005072-198405000-00033  0.427
1983 Imber MJ, Pizzo SV. Clearance and binding of native and defucosylated lactoferrin Biochemical Journal. 212: 249-257. PMID 6882370 DOI: 10.1042/Bj2120249  0.348
1983 Pasqua JJ, Pizzo SV. The role of ligand-ligand interactions in competition by fibrinogen and fibrin degradation products for fibrinogen binding to human platelets. Biochimica Et Biophysica Acta. 757: 282-7. PMID 6849976 DOI: 10.1016/0304-4165(83)90052-1  0.321
1983 Kao KJ, Tsai BS, McKee PA, Lefkowitz RJ, Pizzo SV. Inhibitory effect of ristocetin and factor VIII/von Willebrand factor protein on human platelet adenylate cyclase activity. Thrombosis Research. 30: 301-8. PMID 6408756 DOI: 10.1016/0049-3848(83)90084-1  0.587
1983 Ney KA, Pizzo SV. Fibrinolysis and fibrinogenolysis by Val442-plasmin. Biochimica Et Biophysica Acta. 708: 218-24. PMID 6216916 DOI: 10.1016/0167-4838(82)90223-0  0.305
1983 Hoffman M, Feldman SR, Pizzo SV. Alpha 2-macroglobulin 'fast' forms inhibit superoxide production by activated macrophages. Biochimica Et Biophysica Acta. 760: 421-3. PMID 6194826 DOI: 10.1016/0304-4165(83)90384-7  0.369
1983 Beauchamp CO, Gonias SL, Menapace DP, Pizzo SV. A new procedure for the synthesis of polyethylene glycol-protein adducts; effects on function, receptor recognition, and clearance of superoxide dismutase, lactoferrin, and alpha 2-macroglobulin. Analytical Biochemistry. 131: 25-33. PMID 6193731 DOI: 10.1016/0003-2697(83)90131-8  0.387
1983 Feldman SR, Ney KA, Gonias SL, Pizzo SV. In vitro binding and in vivo clearance of human alpha 2-macroglobulin after reaction with endoproteases from four different classes. Biochemical and Biophysical Research Communications. 114: 757-62. PMID 6192823 DOI: 10.1016/0006-291X(83)90845-8  0.366
1983 Gonias SL, Balber AE, Hubbard WJ, Pizzo SV. Ligand binding, conformational change and plasma elimination of human, mouse and rat alpha-macroglobulin proteinase inhibitors. The Biochemical Journal. 209: 99-105. PMID 6189480 DOI: 10.1042/Bj2090099  0.356
1983 Gonias SL, Pizzo SV. Characterization of functional human alpha 2-macroglobulin half-molecules isolated by limited reduction with dithiothreitol. Biochemistry. 22: 536-46. PMID 6188480 DOI: 10.1021/Bi00272A003  0.328
1982 McComb RD, Jones TR, Pizzo SV, Bigner DD. Localization of factor VIII/von Willebrand factor and glial fibrillary acidic protein in the hemangioblastoma: implications for stromal cell histogenesis. Acta Neuropathologica. 56: 207-13. PMID 6803512 DOI: 10.1007/Bf00690637  0.466
1982 McComb RD, Jones TR, Pizzo SV, Bigner DD. Specificity and sensitivity of immunohistochemical detection of factor VIII/von Willebrand factor antigen in formalin-fixed paraffin-embedded tissue. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 30: 371-7. PMID 6801111 DOI: 10.1177/30.4.6801111  0.456
1982 Johnson WJ, Pizzo SV, Imber MJ, Adams DO. Receptors for maleylated proteins regulate secretion of neutral proteases by murine macrophages Science. 218: 574-576. PMID 6289443 DOI: 10.1126/Science.6289443  0.341
1982 Gonias SL, Reynolds JA, Pizzo SV. Physical properties of human alpha 2-macroglobulin following reaction with methylamine and trypsin. Biochimica Et Biophysica Acta. 705: 306-14. PMID 6181812 DOI: 10.1016/0167-4838(82)90252-7  0.35
1982 Gonias SL, Einarsson M, Pizzo SV. Catabolic pathways for streptokinase, plasmin, and streptokinase activator complex in mice. In vivo reaction of plasminogen activator with alpha 2-macroglobulin. The Journal of Clinical Investigation. 70: 412-23. PMID 6178757 DOI: 10.1172/Jci110631  0.382
1982 Fuchs HE, Shifman MA, Pizzo SV. In vivo catabolism of alpha 1-proteinase inhibitor-trypsin, antithrombin III-thrombin and alpha 2-macroglobulin-methylamine. Biochimica Et Biophysica Acta. 716: 151-7. PMID 6178438 DOI: 10.1016/0304-4165(82)90263-X  0.359
1982 Gonias SL, Pizzo SV. Altered clearance of human alpha 2-macroglobulin complexes following reaction with cis-dichlorodiamineplatinum(II). Biochimica Et Biophysica Acta. 678: 268-74. PMID 6172155 DOI: 10.1016/0304-4165(81)90216-6  0.341
1982 MCCOMB RD, JONES TR, PIZZO SV, BIGNER DD. Immunohistochemical Detection of Factor VIII/von Willebrand Factor in Hyperplastic Endothelial Cells in Glioblastoma Multiforme and Mixed Glioma-Sarcoma Journal of Neuropathology and Experimental Neurology. 41: 497. DOI: 10.1097/00005072-198209000-00001  0.455
1981 Kao KJ, Pizzo SV, McKee PA. A radioreceptor assay for quantitating plasma factor VIII/von Willebrand's protein. Blood. 57: 579-85. PMID 6970055 DOI: 10.1182/Blood.V57.3.579.Bloodjournal573579  0.573
1981 Kao KJ, Sommer JR, Pizzo SV. Modulation of platelet shape and membrane receptor binding by Ca2+-calmodulin complex. Nature. 292: 82-4. PMID 6268985 DOI: 10.1038/292082A0  0.314
1981 McComb RD, Jones TR, Pizzo SV, Bigner DD. 113 IMMUNOPEROXIDASE DETECTION OF FACTOR VIII/VON WILLEBRAND FACTOR (FVIII/vWF) IN GLIOBLASTOMA MULTIFORME (GBM), MIXED GLIOMA-SARCOMA (GS), HEMAN-GIOBLASTOMA (HBL), AND MENINGEAL HEMANGIOPERICYTOMA (HP) Journal of Neuropathology and Experimental Neurology. 40: 336. DOI: 10.1097/00005072-198105000-00120  0.412
1980 Kao KJ, Pizzo SV, McKee PA. Factor VIII/von Willebrand protein. Modification of its carbohydrate causes reduced binding to platelets. The Journal of Biological Chemistry. 255: 10134-9. PMID 6776109  0.544
1980 Hill RL, Pizzo SV, Imber M, Lehrman M, Prieels JP, Glasgow LR, Guthrow CE, Paulson JC. Receptors on hepatocytes that bind ligands containing fucosyl alpha 1,3 N-acetylglucosamine linkages. Birth Defects Original Article Series. 16: 85-91. PMID 6256021  0.47
1979 Kao KJ, Pizzo SV, McKee PA. Platelet receptors for human Factor VIII/von Willebrand protein: functional correlation of receptor occupancy and ristocetin-induced platelet aggregation. Proceedings of the National Academy of Sciences of the United States of America. 76: 5317-20. PMID 315561 DOI: 10.1073/Pnas.76.10.5317  0.575
1979 Switzer ME, Pizzo SV, McKee PA. Is there a precursive, relatively procoagulant-inactive form of normal antihemophilic factor (factor VIII)? Blood. 54: 916-27. PMID 314313 DOI: 10.1182/Blood.V54.4.916.916  0.546
1979 Kao KJ, Pizzo SV, McKee PA. Demonstration and characterization of specific binding sites for factor VIII/von Willebrand factor on human platelets. The Journal of Clinical Investigation. 63: 656-64. PMID 108291 DOI: 10.1172/Jci109348  0.607
1979 Jones TR, Kao KJ, Pizzo SV, Bigner DD. FACTOR VIII-A MARKER OF ENDOTHELIAL CELLS IN NORMAL BRAIN AND GLIOMAS Journal of Neuropathology and Experimental Neurology. 38: 324. DOI: 10.1097/00005072-197905000-00080  0.429
1978 Prieels JP, Pizzo SV, Glasgow LR, Paulson JC, Hill RL. Hepatic receptor that specifically binds oligosaccharides containing fucosyl alpha1 leads to 3 N-acetylglucosamine linkages. Proceedings of the National Academy of Sciences of the United States of America. 75: 2215-9. PMID 276862 DOI: 10.1073/Pnas.75.5.2215  0.658
1978 Sodetz JM, Paulson JC, Pizzo SV, McKee PA. Carbohydrate on human factor VIII/von Willebrand factor. Impairment of function by removal of specific galactose residues. The Journal of Biological Chemistry. 253: 7202-6. PMID 100492  0.573
1977 Sodetz JM, Pizzo SV, McKee PA. Relationship of sialic acid to function and in vivo survival of human factor VIII/von Willebrand factor protein. The Journal of Biological Chemistry. 252: 5538-46. PMID 301877  0.519
1976 Daniel TM, Pizzo SV, Mckee PA. Comparison of ancrod and heparin as anticoagulants following endarterectomy in the dog. Annals of Surgery. 184: 223-8. PMID 952568 DOI: 10.1097/00000658-197608000-00015  0.537
1976 Slade CL, Pizzo SV, Taylor LM, Steinman HM, McKee PA. Characterization of fragment E from fibrinogen and cross-linked fibrin. The Journal of Biological Chemistry. 251: 1591-6. PMID 815259  0.521
1973 Schwartz ML, Pizzo SV, Sullivan JB, Hill RL, McKee PA. A comparative study of crosslinked and noncrosslinked fibrin from the major classes of vertebrates. Thrombosis Et Diathesis Haemorrhagica. 29: 313-38. PMID 4762256  0.587
1973 Schwartz ML, Pizzo SV, Hill RL, McKee PA. Human Factor XIII from plasma and platelets. Molecular weights, subunit structures, proteolytic activation, and cross-linking of fibrinogen and fibrin. The Journal of Biological Chemistry. 248: 1395-407. PMID 4405643  0.632
1973 Pizzo SV, Schwartz ML, Hill RL, McKee PA. The effect of plasmin on the subunit structure of human fibrin. The Journal of Biological Chemistry. 248: 4574-83. PMID 4268861  0.619
1973 Shapiro GA, Andersen JC, Pizzo SV, McKee PA. The subunit structure of normal and hemophilic factor VIII. The Journal of Clinical Investigation. 52: 2198-210. PMID 4199414 DOI: 10.1172/Jci107405  0.587
1973 Pizzo SV, Taylor LM, Schwartz ML, Hill RL, McKee PA. Subunit structure of fragment D from fibrinogen and cross-linked fibrin. The Journal of Biological Chemistry. 248: 4584-90. PMID 4198060  0.6
1972 McKee PA, Schwartz ML, Pizzo SV, Hill RL. Cross-linking of fibrin by fibrin=stabilizing factor. Annals of the New York Academy of Sciences. 202: 127-48. PMID 4565368 DOI: 10.1111/J.1749-6632.1972.Tb16326.X  0.626
1972 Pizzo SV, Schwartz ML, Hill RL, McKee PA. Mechanism of ancrod anticoagulation. A direct proteolytic effect on fibrin. The Journal of Clinical Investigation. 51: 2841-50. PMID 4263497 DOI: 10.1172/Jci107107  0.697
1972 Pizzo SV, Schwartz ML, Hill RL, McKee PA. The effect of plasmin on the subunit structure of human fibrinogen. The Journal of Biological Chemistry. 247: 636-45. PMID 4258027  0.62
1971 Schwartz ML, Pizzo SV, Hill RL, McKee PA, Bird RM. Purification and subunit structure of human plasma and platelet fibrin-stabilizing factor. The Journal of Laboratory and Clinical Medicine. 78: 848. PMID 5128900  0.623
1971 Schwartz ML, Pizzo SV, Hill RL, McKee PA. The subunit structures of human plasma and platelet factor XIII (fibrin-stabilizing factor). The Journal of Biological Chemistry. 246: 5851-4. PMID 5096097  0.621
1971 Schwartz ML, Pizzo SV, McKee PA. Minimal brain dysfunction and methylphenidate. The New England Journal of Medicine. 285: 293. PMID 5090403  0.461
1971 Schwartz ML, Pizzo SV, Hill RL, McKee PA. The effect of fibrin-stabilizing factor on the subunit structure of human fibrin. The Journal of Clinical Investigation. 50: 1506-13. PMID 5090065 DOI: 10.1172/Jci106636  0.671
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