H. Lee Sweeney - Publications

Affiliations: 
1984 Physiology and Biophysics Harvard Medical School, Boston, MA, United States 

97 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Pospich S, Sweeney HL, Houdusse A, Raunser S. High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism. Elife. 10. PMID 34812732 DOI: 10.7554/eLife.73724  0.633
2021 Hammers DW, Hart CC, Matheny MK, Heimsath EG, Lee YI, Hammer JA, Cheney RE, Sweeney HL. Filopodia powered by class X myosin promote fusion of mammalian myoblasts. Elife. 10. PMID 34519272 DOI: 10.7554/eLife.72419  0.35
2020 Hammers DW, Hart CC, Matheny MK, Wright LA, Armellini M, Barton ER, Sweeney HL. The D2.mdx mouse as a preclinical model of the skeletal muscle pathology associated with Duchenne muscular dystrophy. Scientific Reports. 10: 14070. PMID 32826942 DOI: 10.1038/S41598-020-70987-Y  0.615
2020 Sweeney HL, Houdusse A, Robert-Paganin J. Myosin Structures. Advances in Experimental Medicine and Biology. 1239: 7-19. PMID 32451853 DOI: 10.1007/978-3-030-38062-5_2  0.65
2020 Qin X, Yoo H, Man Cheng HC, Nguyen QQ, Li J, Liu X, Prunetti L, Chen X, Liu T, Sweeney HL, Park H. Simultaneous tracking of two motor domains reveals near simultaneous steps and stutter steps of myosin 10 on actin filament bundles. Biochemical and Biophysical Research Communications. PMID 32081426 DOI: 10.1016/J.Bbrc.2020.02.039  0.308
2019 Hammers DW, Hart CC, Patsalos A, Matheny MK, Wright LA, Nagy L, Sweeney HL. Glucocorticoids counteract hypertrophic effects of myostatin inhibition in dystrophic muscle. Jci Insight. PMID 31830002 DOI: 10.1172/Jci.Insight.133276  0.303
2019 Robert-Paganin J, Pylypenko O, Kikuti C, Sweeney HL, Houdusse A. Force Generation by Myosin Motors: A Structural Perspective. Chemical Reviews. PMID 31689091 DOI: 10.1021/Acs.Chemrev.9B00264  0.615
2019 Barton ER, Pham J, Brisson BK, Park S, Smith LR, Liu M, Tian Z, Hammers DW, Vassilakos G, Sweeney HL. Functional muscle hypertrophy by increased insulin-like growth factor 1 does not require dysferlin. Muscle & Nerve. PMID 31323135 DOI: 10.1002/Mus.26641  0.605
2018 Blanc F, Isabet T, Benisty H, Sweeney HL, Cecchini M, Houdusse A. An intermediate along the recovery stroke of myosin VI revealed by X-ray crystallography and molecular dynamics. Proceedings of the National Academy of Sciences of the United States of America. PMID 29844196 DOI: 10.1073/Pnas.1711512115  0.597
2018 Sweeney HL, Hammers DW. Muscle Contraction. Cold Spring Harbor Perspectives in Biology. 10. PMID 29419405 DOI: 10.1101/cshperspect.a023200  0.347
2017 Hammers DW, Merscham-Banda M, Hsiao JY, Engst S, Hartman JJ, Sweeney HL. Supraphysiological levels of GDF11 induce striated muscle atrophy. Embo Molecular Medicine. PMID 28270449 DOI: 10.15252/emmm.201607231  0.304
2016 Liu M, Hammers DW, Barton ER, Sweeney HL. Activin Receptor Type IIB Inhibition Improves Muscle Phenotype and Function in a Mouse Model of Spinal Muscular Atrophy. Plos One. 11: e0166803. PMID 27870893 DOI: 10.1371/Journal.Pone.0166803  0.642
2016 Houdusse A, Sweeney HL. How Myosin Generates Force on Actin Filaments. Trends in Biochemical Sciences. PMID 27717739 DOI: 10.1016/J.Tibs.2016.09.006  0.616
2016 Ropars V, Yang Z, Isabet T, Blanc F, Zhou K, Lin T, Liu X, Hissier P, Samazan F, Amigues B, Yang ED, Park H, Pylypenko O, Cecchini M, Sindelar CV, ... Sweeney HL, et al. The myosin X motor is optimized for movement on actin bundles. Nature Communications. 7: 12456. PMID 27580874 DOI: 10.1038/Ncomms12456  0.623
2016 Capote J, Kramerova I, Martinez L, Vetrone S, Barton ER, Sweeney HL, Miceli MC, Spencer MJ. Osteopontin ablation ameliorates muscular dystrophy by shifting macrophages to a pro-regenerative phenotype. The Journal of Cell Biology. 213: 275-88. PMID 27091452 DOI: 10.1083/Jcb.201510086  0.632
2016 Wulf SF, Ropars V, Fujita-Becker S, Oster M, Hofhaus G, Trabuco LG, Pylypenko O, Sweeney HL, Houdusse AM, Schröder RR. Force-producing ADP state of myosin bound to actin. Proceedings of the National Academy of Sciences of the United States of America. PMID 26976594 DOI: 10.1073/Pnas.1516598113  0.628
2016 Abrams J, Einhorn Z, Seiler C, Zong AB, Sweeney HL, Pack M. Graded effects of unregulated smooth muscle myosin on intestinal architecture, intestinal motility, and vascular function in zebrafish. Disease Models & Mechanisms. PMID 26893369 DOI: 10.1242/dmm.023309  0.302
2016 Schroeder RR, Wulf SF, Ropars V, Fujita-Becker S, Oster M, Hofhaus G, Trabuco LG, Pylypenko O, Sweeney HL, Houdusse A. The Force Producing ADP State of Myosin Bound to Actin Biophysical Journal. 110: 13a. DOI: 10.1016/j.bpj.2015.11.129  0.593
2015 Smith LR, Hammers DW, Sweeney HL, Barton ER. Increased collagen cross-linking is a signature of dystrophin-deficient muscle. Muscle & Nerve. PMID 26616495 DOI: 10.1002/Mus.24998  0.605
2015 Llinas P, Isabet T, Song L, Ropars V, Zong B, Benisty H, Sirigu S, Morris C, Kikuti C, Safer D, Sweeney HL, Houdusse A. How actin initiates the motor activity of Myosin. Developmental Cell. 33: 401-12. PMID 25936506 DOI: 10.1016/J.Bpj.2014.11.160  0.652
2015 Pylypenko O, Song L, Shima A, Yang Z, Houdusse AM, Sweeney HL. Myosin VI deafness mutation prevents the initiation of processive runs on actin. Proceedings of the National Academy of Sciences of the United States of America. 112: E1201-9. PMID 25751888 DOI: 10.1073/Pnas.1420989112  0.621
2014 Mukherjea M, Ali MY, Kikuti C, Safer D, Yang Z, Sirkia H, Ropars V, Houdusse A, Warshaw DM, Sweeney HL. Myosin VI must dimerize and deploy its unusual lever arm in order to perform its cellular roles. Cell Reports. 8: 1522-32. PMID 25159143 DOI: 10.1016/J.Celrep.2014.07.041  0.628
2014 Tsai MH, Chang AN, Huang J, He W, Sweeney HL, Zhu M, Kamm KE, Stull JT. Constitutive phosphorylation of myosin phosphatase targeting subunit-1 in smooth muscle. The Journal of Physiology. 592: 3031-51. PMID 24835173 DOI: 10.1113/Jphysiol.2014.273011  0.306
2014 Forbes SC, Bish LT, Ye F, Spinazzola J, Baligand C, Plant D, Vandenborne K, Barton ER, Sweeney HL, Walter GA. Gene transfer of arginine kinase to skeletal muscle using adeno-associated virus. Gene Therapy. 21: 387-92. PMID 24572791 DOI: 10.1038/Gt.2014.9  0.573
2013 Selsby JT, Acosta P, Sleeper MM, Barton ER, Sweeney HL. Long-term wheel running compromises diaphragm function but improves cardiac and plantarflexor function in the mdx mouse. Journal of Applied Physiology (Bethesda, Md. : 1985). 115: 660-6. PMID 23823150 DOI: 10.1152/Japplphysiol.00252.2013  0.614
2013 Ye F, Mathur S, Liu M, Borst SE, Walter GA, Sweeney HL, Vandenborne K. Overexpression of insulin-like growth factor-1 attenuates skeletal muscle damage and accelerates muscle regeneration and functional recovery after disuse. Experimental Physiology. 98: 1038-52. PMID 23291913 DOI: 10.1113/Expphysiol.2012.070722  0.305
2013 Ali MY, Previs SB, Trybus KM, Sweeney HL, Warshaw DM. Myosin VI has a one track mind versus myosin Va when moving on actin bundles or at an intersection. Traffic (Copenhagen, Denmark). 14: 70-81. PMID 23046080 DOI: 10.1111/tra.12017  0.32
2012 Ménétrey J, Isabet T, Ropars V, Mukherjea M, Pylypenko O, Liu X, Perez J, Vachette P, Sweeney HL, Houdusse AM. Processive steps in the reverse direction require uncoupling of the lead head lever arm of myosin VI. Molecular Cell. 48: 75-86. PMID 22940248 DOI: 10.1016/J.Molcel.2012.07.034  0.641
2012 Selsby JT, Morine KJ, Pendrak K, Barton ER, Sweeney HL. Rescue of dystrophic skeletal muscle by PGC-1α involves a fast to slow fiber type shift in the mdx mouse. Plos One. 7: e30063. PMID 22253880 DOI: 10.1371/Journal.Pone.0030063  0.612
2012 Llinas P, Pylypenko O, Isabet T, Mukherjea M, Sweeney HL, Houdusse AM. How myosin motors power cellular functions: an exciting journey from structure to function: based on a lecture delivered at the 34th FEBS Congress in Prague, Czech Republic, July 2009. The Febs Journal. 279: 551-62. PMID 22171985 DOI: 10.1111/J.1742-4658.2011.08449.X  0.636
2012 Qaisar R, Renaud G, Morine K, Barton ER, Sweeney HL, Larsson L. Is functional hypertrophy and specific force coupled with the addition of myonuclei at the single muscle fiber level? Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 1077-85. PMID 22125316 DOI: 10.1096/Fj.11-192195  0.662
2011 Bish LT, Yarchoan M, Sleeper MM, Gazzara JA, Morine KJ, Acosta P, Barton ER, Sweeney HL. Chronic losartan administration reduces mortality and preserves cardiac but not skeletal muscle function in dystrophic mice. Plos One. 6: e20856. PMID 21731628 DOI: 10.1371/Journal.Pone.0020856  0.623
2011 Pylypenko O, Song L, Squires G, Liu X, Zong AB, Houdusse A, Sweeney HL. Role of insert-1 of myosin VI in modulating nucleotide affinity. The Journal of Biological Chemistry. 286: 11716-23. PMID 21278381 DOI: 10.1074/Jbc.M110.200626  0.59
2011 Shima A, Pham J, Blanco E, Barton ER, Sweeney HL, Matsuda R. IGF-I and vitamin C promote myogenic differentiation of mouse and human skeletal muscle cells at low temperatures. Experimental Cell Research. 317: 356-66. PMID 21070767 DOI: 10.1016/J.Yexcr.2010.11.001  0.584
2011 Sen S, Tewari M, Zajac A, Barton E, Sweeney HL, Discher DE. Upregulation of paxillin and focal adhesion signaling follows Dystroglycan Complex deletions and promotes a hypertensive state of differentiation. European Journal of Cell Biology. 90: 249-60. PMID 20663583 DOI: 10.1016/J.Ejcb.2010.06.005  0.603
2010 Selsby J, Pendrak K, Zadel M, Tian Z, Pham J, Carver T, Acosta P, Barton E, Sweeney HL. Leupeptin-based inhibitors do not improve the mdx phenotype. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 299: R1192-201. PMID 20844259 DOI: 10.1152/Ajpregu.00586.2009  0.618
2010 Stevens-Lapsley JE, Ye F, Liu M, Borst SE, Conover C, Yarasheski KE, Walter GA, Sweeney HL, Vandenborne K. Impact of viral-mediated IGF-I gene transfer on skeletal muscle following cast immobilization. American Journal of Physiology. Endocrinology and Metabolism. 299: E730-40. PMID 20739512 DOI: 10.1152/Ajpendo.00230.2010  0.326
2010 Morine KJ, Bish LT, Selsby JT, Gazzara JA, Pendrak K, Sleeper MM, Barton ER, Lee SJ, Sweeney HL. Activin IIB receptor blockade attenuates dystrophic pathology in a mouse model of Duchenne muscular dystrophy. Muscle & Nerve. 42: 722-30. PMID 20730876 DOI: 10.1002/Mus.21743  0.61
2010 Wang B, Yang Z, Brisson BK, Feng H, Zhang Z, Welch EM, Peltz SW, Barton ER, Brown RH, Sweeney HL. Membrane blebbing as an assessment of functional rescue of dysferlin-deficient human myotubes via nonsense suppression. Journal of Applied Physiology (Bethesda, Md. : 1985). 109: 901-5. PMID 20558759 DOI: 10.1152/Japplphysiol.01366.2009  0.588
2010 Barton ER, Wang BJ, Brisson BK, Sweeney HL. Diaphragm displays early and progressive functional deficits in dysferlin-deficient mice. Muscle & Nerve. 42: 22-9. PMID 20544921 DOI: 10.1002/Mus.21645  0.646
2010 Morine KJ, Sleeper MM, Barton ER, Sweeney HL. Overexpression of SERCA1a in the mdx diaphragm reduces susceptibility to contraction-induced damage. Human Gene Therapy. 21: 1735-9. PMID 20540606 DOI: 10.1089/Hum.2010.077  0.614
2010 Sweeney HL, Houdusse A. Myosin VI Rewrites the Rules for Myosin Motors Cell. 141: 573-582. PMID 20478251 DOI: 10.1016/J.Cell.2010.04.028  0.646
2010 Sweeney HL, Houdusse A. Structural and functional insights into the myosin motor mechanism Annual Review of Biophysics. 39: 539-557. PMID 20192767 DOI: 10.1146/Annurev.Biophys.050708.133751  0.672
2010 Morine KJ, Bish LT, Pendrak K, Sleeper MM, Barton ER, Sweeney HL. Systemic myostatin inhibition via liver-targeted gene transfer in normal and dystrophic mice. Plos One. 5: e9176. PMID 20161803 DOI: 10.1371/Journal.Pone.0009176  0.582
2010 Shima A, Barton E, Sweeney H, Matsuda R. P3.20 Mouse and human skeletal muscle cells differentiate in a temperature-dependent manner Neuromuscular Disorders. 20: 647. DOI: 10.1016/J.Nmd.2010.07.162  0.599
2010 Kim H, Hsin J, Liu Y, Mukherjea M, Safer D, Houdusse A, Sweeney HL, Schulten K, Selvin PR. Single-Molecule and Molecular Dynamics Study of the Dimerization of Myosin VI Medial Tail Domain Biophysical Journal. 98: 724a. DOI: 10.1016/J.Bpj.2009.12.3969  0.58
2010 Mukherjea M, Llinas P, Safer D, Houdusse A, Sweeney HL. Dimerization is Essential for the Large Step Size of Myosin VI Biophysical Journal. 98: 724a. DOI: 10.1016/J.Bpj.2009.12.3967  0.648
2010 Liu Y, Hsin J, Kim H, Houdusse A, Sweeney HL, Selvin PR, Schulten K. Steered Molecular Dynamics Simulation of Unfolding of Myosin VI Proximal Tail Domain Biophysical Journal. 98: 724a. DOI: 10.1016/J.Bpj.2009.12.3966  0.596
2009 Mukherjea M, Llinas P, Kim H, Travaglia M, Safer D, Ménétrey J, Franzini-Armstrong C, Selvin PR, Houdusse A, Sweeney HL. Myosin VI dimerization triggers an unfolding of a three-helix bundle in order to extend its reach. Molecular Cell. 35: 305-15. PMID 19664948 DOI: 10.1016/J.Molcel.2009.07.010  0.646
2009 Qaiasr R, Morine K, Barton E, Sweeney H, Larsson L. EM.P.1.07 Effects of muscle hypertrophy on individual myonuclear domain sizes in single muscle fibers from myostatin deficient or IGF-1 over-expressing mice Neuromuscular Disorders. 19: 551. DOI: 10.1016/J.Nmd.2009.06.028  0.632
2009 Mukherjea M, Safer D, Ménétrey J, Llinas P, Houdusse A, Sweeney HL. Myosin VI Dimerizes And Walks Processively Along Actin Biophysical Journal. 96: 142a. DOI: 10.1016/J.Bpj.2008.12.3884  0.641
2009 Phichith D, Travaglia M, Yang Z, Zong AB, Safer D, Franzini-Armstrong C, Sweeney HL. Cargo-mediated dimerization of Myosin VI Biophysical Journal. 96: 141a. DOI: 10.1016/J.Bpj.2008.12.3877  0.36
2008 Millay DP, Sargent MA, Osinska H, Baines CP, Barton ER, Vuagniaux G, Sweeney HL, Robbins J, Molkentin JD. Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy. Nature Medicine. 14: 442-7. PMID 18345011 DOI: 10.1038/Nm1736  0.604
2008 Ménétrey J, Llinas P, Cicolari J, Squires G, Liu X, Li A, Sweeney HL, Houdusse A. The post-rigor structure of myosin VI and implications for the recovery stroke. The Embo Journal. 27: 244-52. PMID 18046460 DOI: 10.1038/Sj.Emboj.7601937  0.635
2008 Houdusse A, Llinas P, Menetrey J, Cicolari J, Sweeney H. Structural description of the ATPase cycle of a myosin that moves backward Acta Crystallographica Section a Foundations of Crystallography. 64: C78-C79. DOI: 10.1107/S0108767308097481  0.572
2007 Ménétrey J, Llinas P, Mukherjea M, Sweeney HL, Houdusse A. The structural basis for the large powerstroke of myosin VI. Cell. 131: 300-8. PMID 17956731 DOI: 10.1016/J.Cell.2007.08.027  0.643
2007 Sweeney HL, Park H, Zong AB, Yang Z, Selvin PR, Rosenfeld SS. How myosin VI coordinates its heads during processive movement. The Embo Journal. 26: 2682-92. PMID 17510632 DOI: 10.1038/Sj.Emboj.7601720  0.331
2007 Welch EM, Barton ER, Zhuo J, Tomizawa Y, Friesen WJ, Trifillis P, Paushkin S, Patel M, Trotta CR, Hwang S, Wilde RG, Karp G, Takasugi J, Chen G, Jones S, ... ... Sweeney HL, et al. PTC124 targets genetic disorders caused by nonsense mutations. Nature. 447: 87-91. PMID 17450125 DOI: 10.1038/Nature05756  0.583
2007 Parsons SA, Millay DP, Sargent MA, Naya FJ, McNally EM, Sweeney HL, Molkentin JD. Genetic disruption of calcineurin improves skeletal muscle pathology and cardiac disease in a mouse model of limb-girdle muscular dystrophy. The Journal of Biological Chemistry. 282: 10068-78. PMID 17289669 DOI: 10.1074/Jbc.M609368200  0.332
2007 Park H, Li A, Chen LQ, Houdusse A, Selvin PR, Sweeney HL. The unique insert at the end of the myosin VI motor is the sole determinant of directionality. Proceedings of the National Academy of Sciences of the United States of America. 104: 778-83. PMID 17213313 DOI: 10.1073/Pnas.0610066104  0.631
2007 Sweeney HL, Houdusse A. What can myosin VI do in cells? Current Opinion in Cell Biology. 19: 57-66. PMID 17175153 DOI: 10.1016/J.Ceb.2006.12.005  0.63
2005 Purcell TJ, Sweeney HL, Spudich JA. A force-dependent state controls the coordination of processive myosin V. Proceedings of the National Academy of Sciences of the United States of America. 102: 13873-8. PMID 16150709 DOI: 10.1073/Pnas.0506441102  0.303
2005 Chevreux G, Potier N, Van Dorsselaer A, Bahloul A, Houdusse A, Wells A, Sweeney HL. Electrospray ionization mass spectrometry studies of noncovalent myosin VI complexes reveal a new specific calmodulin binding site. Journal of the American Society For Mass Spectrometry. 16: 1367-76. PMID 15979337 DOI: 10.1016/J.Jasms.2005.03.023  0.587
2005 Morris CA, Morris LD, Kennedy AR, Sweeney HL. Attenuation of skeletal muscle atrophy via protease inhibition. Journal of Applied Physiology (Bethesda, Md. : 1985). 99: 1719-27. PMID 15976355 DOI: 10.1152/japplphysiol.01419.2004  0.307
2005 Ménétrey J, Bahloul A, Wells AL, Yengo CM, Morris CA, Sweeney HL, Houdusse A. The structure of the myosin VI motor reveals the mechanism of directionality reversal. Nature. 435: 779-85. PMID 15944696 DOI: 10.1038/Nature03592  0.649
2005 Rosenfeld SS, Houdusse A, Sweeney HL. Magnesium regulates ADP dissociation from myosin V Journal of Biological Chemistry. 280: 6072-6079. PMID 15579901 DOI: 10.1074/Jbc.M412717200  0.591
2004 Sweeney HL, Houdusse A. The motor mechanism of myosin V: insights for muscle contraction. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 359: 1829-41. PMID 15647159 DOI: 10.1098/Rstb.2004.1576  0.675
2004 Coureux PD, Sweeney HL, Houdusse A. Three myosin V structures delineate essential features of chemo-mechanical transduction Embo Journal. 23: 4527-4537. PMID 15510214 DOI: 10.1038/Sj.Emboj.7600458  0.633
2004 Yildiz A, Park H, Safer D, Yang Z, Chen LQ, Selvin PR, Sweeney HL. Myosin VI steps via a hand-over-hand mechanism with its lever arm undergoing fluctuations when attached to actin. The Journal of Biological Chemistry. 279: 37223-6. PMID 15254036 DOI: 10.1074/Jbc.C400252200  0.309
2004 Bahloul A, Chevreux G, Wells AL, Martin D, Nolt J, Yang Z, Chen LQ, Potier N, Van Dorsselaer A, Rosenfeld S, Houdusse A, Sweeney HL. The unique insert in myosin VI is a structural calcium-calmodulin binding site. Proceedings of the National Academy of Sciences of the United States of America. 101: 4787-92. PMID 15037754 DOI: 10.1073/Pnas.0306892101  0.591
2004 Lee S, Barton ER, Sweeney HL, Farrar RP. Viral expression of insulin-like growth factor-I enhances muscle hypertrophy in resistance-trained rats. Journal of Applied Physiology (Bethesda, Md. : 1985). 96: 1097-104. PMID 14766764 DOI: 10.1152/Japplphysiol.00479.2003  0.592
2003 Kobinger GP, Louboutin JP, Barton ER, Sweeney HL, Wilson JM. Correction of the dystrophic phenotype by in vivo targeting of muscle progenitor cells. Human Gene Therapy. 14: 1441-9. PMID 14577924 DOI: 10.1089/104303403769211655  0.612
2003 Coureux PD, Wells AL, Ménétrey J, Yengo CM, Morris CA, Sweeney HL, Houdusse A. A structural state of the myosin V motor without bound nucleotide. Nature. 425: 419-23. PMID 14508494 DOI: 10.1038/Nature01927  0.651
2003 Joel PB, Sweeney HL, Trybus KM. Addition of lysines to the 50/20 kDa junction of myosin strengthens weak binding to actin without affecting the maximum ATPase activity Biochemistry. 42: 9160-9166. PMID 12885250 DOI: 10.1021/bi034415j  0.328
2003 Chatterjee S, Bish LT, Jayasankar V, Stewart AS, Woo YJ, Crow MT, Gardner TJ, Sweeney HL. Blocking the development of postischemic cardiomyopathy with viral gene transfer of the apoptosis repressor with caspase recruitment domain. The Journal of Thoracic and Cardiovascular Surgery. 125: 1461-9. PMID 12830068 DOI: 10.1016/S0022-5223(02)73229-7  0.526
2003 Xiao M, Reifenberger JG, Wells AL, Baldacchino C, Chen LQ, Ge P, Sweeney HL, Selvin PR. An actin-dependent conformational change in myosin. Nature Structural Biology. 10: 402-8. PMID 12679807 DOI: 10.1038/Nsb916  0.326
2002 Barton ER, Morris L, Musaro A, Rosenthal N, Sweeney HL. Muscle-specific expression of insulin-like growth factor I counters muscle decline in mdx mice. The Journal of Cell Biology. 157: 137-48. PMID 11927606 DOI: 10.1083/Jcb.200108071  0.644
2002 Chatterjee S, Jayasankar V, Bish LT, Stewart AS, Woo Y, Crow MT, Gardner TJ, Sweeney H. 05 Viral gene transfer of ARC and BCL-2 confers similar protection against cardiomyopathy after myocardial ischemia Journal of Molecular and Cellular Cardiology. 34: A32. DOI: 10.1016/S0022-2828(02)90181-1  0.512
2001 Rock RS, Rice SE, Wells AL, Purcell TJ, Spudich JA, Sweeney HL. Myosin VI is a processive motor with a large step size. Proceedings of the National Academy of Sciences of the United States of America. 98: 13655-9. PMID 11707568 DOI: 10.1073/Pnas.191512398  0.345
2001 De La Cruz EM, Ostap EM, Sweeney HL. Kinetic mechanism and regulation of myosin VI. The Journal of Biological Chemistry. 276: 32373-81. PMID 11423557 DOI: 10.1074/Jbc.M104136200  0.31
2001 Houdusse A, Sweeney HL. Myosin motors: Missing structures and hidden springs Current Opinion in Structural Biology. 11: 182-194. PMID 11297926 DOI: 10.1016/S0959-440X(00)00188-3  0.661
2001 Musarò A, McCullagh K, Paul A, Houghton L, Dobrowolny G, Molinaro M, Barton ER, Sweeney HL, Rosenthal N. Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle. Nature Genetics. 27: 195-200. PMID 11175789 DOI: 10.1038/84839  0.637
2000 Rosenfeld SS, Xing J, Whitaker M, Cheung HC, Brown F, Wells A, Milligan RA, Sweeney HL. Kinetic and spectroscopic evidence for three actomyosin:ADP states in smooth muscle. The Journal of Biological Chemistry. 275: 25418-26. PMID 10827085 DOI: 10.1074/Jbc.M002685200  0.38
1999 De La Cruz EM, Wells AL, Rosenfeld SS, Ostap EM, Sweeney HL. The kinetic mechanism of myosin V. Proceedings of the National Academy of Sciences of the United States of America. 96: 13726-31. PMID 10570140 DOI: 10.1073/Pnas.96.24.13726  0.316
1999 Wells AL, Lin AW, Chen LQ, Safer D, Cain SM, Hasson T, Carragher BO, Milligan RA, Sweeney HL. Myosin VI is an actin-based motor that moves backwards. Nature. 401: 505-8. PMID 10519557 DOI: 10.1038/46835  0.343
1999 Dantzig JA, Barsotti RJ, Manz S, Sweeney HL, Goldman YE. The ADP release step of the smooth muscle cross-bridge cycle is not directly associated with force generation. Biophysical Journal. 77: 386-97. PMID 10388765 DOI: 10.1016/S0006-3495(99)76897-9  0.366
1999 Barton-Davis ER, Shoturma DI, Musaro A, Rosenthal N, Sweeney HL. Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function. Proceedings of the National Academy of Sciences of the United States of America. 95: 15603-7. PMID 9861016 DOI: 10.1073/Pnas.95.26.15603  0.319
1998 Trybus KM, Naroditskaya V, Sweeney HL. The light chain-binding domain of the smooth muscle myosin heavy chain is not the only determinant of regulation Journal of Biological Chemistry. 273: 18423-18428. PMID 9660810 DOI: 10.1074/jbc.273.29.18423  0.376
1995 Yang Z, Sweeney HL. Restoration of phosphorylation-dependent regulation to the skeletal muscle myosin regulatory light chain Journal of Biological Chemistry. 270: 24646-24649. PMID 7559573 DOI: 10.1074/Jbc.270.42.24646  0.307
1995 Whittaker M, Wilson-Kubalek EM, Smith JE, Faust L, Milligan RA, Sweeney HL. A 35-A movement of smooth muscle myosin on ADP release. Nature. 378: 748-51. PMID 7501026 DOI: 10.1038/378748A0  0.326
1993 Petrof BJ, Shrager JB, Stedman HH, Kelly AM, Sweeney HL. Dystrophin protects the sarcolemma from stresses developed during muscle contraction Proceedings of the National Academy of Sciences of the United States of America. 90: 3710-3714. PMID 8475120 DOI: 10.1073/Pnas.90.8.3710  0.315
1991 Stedman HH, Sweeney HL, Shrager JB, Maguire HC, Panettieri RA, Petrof B, Narusawa M, Leferovich JM, Sladky JT, Kelly AM. The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy. Nature. 352: 536-9. PMID 1865908 DOI: 10.1038/352536A0  0.308
1987 Sweeney HL, Corteselli SA, Kushmerick MJ. Measurements on permeabilized skeletal muscle fibers during continuous activation. The American Journal of Physiology. 252: C575-80. PMID 3578507 DOI: 10.1152/ajpcell.1987.252.5.C575  0.569
1986 Sweeney HL, Kushmerick MJ, Mabuchi K, Gergely J, Sréter FA. Velocity of shortening and myosin isozymes in two types of rabbit fast-twitch muscle fibers. The American Journal of Physiology. 251: C431-4. PMID 3019147 DOI: 10.1152/Ajpcell.1986.251.3.C431  0.562
1985 Sweeney HL, Kushmerick MJ. Myosin phosphorylation in permeabilized rabbit psoas fibers. The American Journal of Physiology. 249: C362-5. PMID 4037077 DOI: 10.1152/ajpcell.1985.249.3.C362  0.549
1985 Sweeney HL, Kushmerick MJ, Mabuchi K, Gergely J, Sreter F. DIFFERENTIAL MYOSIN ISOZYME DISTRIBUTIONS AND SHORTENING VELOCITIES OF RABBIT SKINED SKELETAL MUSCLE FIBERS Medicine & Science in Sports & Exercise. 17: 244. DOI: 10.1249/00005768-198504000-00279  0.587
1984 Meyer RA, Sweeney HL, Kushmerick MJ. A simple analysis of the "phosphocreatine shuttle". The American Journal of Physiology. 246: C365-77. PMID 6372517 DOI: 10.1152/ajpcell.1984.246.5.C365  0.502
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