Carolyn Worby - Related publications

University of California, San Diego, La Jolla, CA 
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50 most relevant papers in past 60 days:
Year Citation  Score
2019 Leroux AE, Gross LZF, Sacerdoti M, Biondi RM. Allosteric Regulation of Protein Kinases Downstream of PI3-Kinase Signalling. Advances in Experimental Medicine and Biology. 1163: 279-311. PMID 31707708 DOI: 10.1007/978-981-13-8719-7_12   
2019 Sitaram P, Uyemura B, Malarkannan S, Riese MJ. Beyond the Cell Surface: Targeting Intracellular Negative Regulators to Enhance T cell Anti-Tumor Activity. International Journal of Molecular Sciences. 20. PMID 31756921 DOI: 10.3390/ijms20235821   
2019 Nabhan M, Gallais Y, Pallardy M, Turbica I. Growth Hormone Aggregates Activation of Human Dendritic Cells Is Controlled by Rac1 and PI3 Kinase Signaling Pathways. Journal of Pharmaceutical Sciences. PMID 31520643 DOI: 10.1016/j.xphs.2019.09.007   
2019 Horta MAC, Thieme N, Gao Y, Burnum-Johnson KE, Nicora CD, Gritsenko MA, Lipton MS, Mohanraj K, de Assis LJ, Lin L, Tian C, Braus GH, Borkovich KA, Schmoll M, Larrondo LF, et al. Broad Substrate-Specific Phosphorylation Events Are Associated With the Initial Stage of Plant Cell Wall Recognition in . Frontiers in Microbiology. 10: 2317. PMID 31736884 DOI: 10.3389/fmicb.2019.02317   
2019 Rathinaswamy MK, Burke JE. Class I phosphoinositide 3-kinase (PI3K) regulatory subunits and their roles in signaling and disease. Advances in Biological Regulation. 100657. PMID 31611073 DOI: 10.1016/j.jbior.2019.100657   
2019 Zamora-Olivares D, Kaoud TS, Zeng L, Pridgen JR, Zhuang DL, Ekpo YE, Nye JR, Telles M, Anslyn EV, Dalby KN. Quantification of ERK kinase activity in biological samples using differential sensing. Acs Chemical Biology. PMID 31775004 DOI: 10.1021/acschembio.9b00580   
2019 Zhou C, Qian X, Hu M, Zhang R, Liu N, Huang Y, Yang J, Zhang J, Bai H, Yang Y, Wang Y, Ali D, Michalak M, Chen XZ, Tang J. STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase complex I. Autophagy. 1-21. PMID 31696776 DOI: 10.1080/15548627.2019.1687212   
2019 Liu H, Ding J, Köhnlein K, Urban N, Ori A, Villavicencio-Lorini P, Walentek P, Klotz LO, Hollemann T, Pfirrmann T. The GID ubiquitin ligase complex is a regulator of AMPK activity and organismal lifespan. Autophagy. 1-17. PMID 31795790 DOI: 10.1080/15548627.2019.1695399   
2019 Vitrac H, Mallampalli VKPS, Dowhan W. Importance of phosphorylation/dephosphorylation cycles on lipid-dependent modulation of membrane protein topology by posttranslational phosphorylation. The Journal of Biological Chemistry. PMID 31645436 DOI: 10.1074/jbc.RA119.010785   
2019 Dustin CM, Heppner DE, Lin MJ, van der Vliet A. Redox regulation of tyrosine kinase signaling: More than meet the eye. Journal of Biochemistry. PMID 31599960 DOI: 10.1093/jb/mvz085   
2019 Sulpizio A, Minelli ME, Wan M, Burrowes PD, Wu X, Sanford EJ, Shin JH, Williams BC, Goldberg ML, Smolka MB, Mao Y. Protein polyglutamylation catalyzed by the bacterial calmodulin-dependent pseudokinase SidJ. Elife. 8. PMID 31682223 DOI: 10.7554/eLife.51162   
2019 Zhang ZY, Miao LF, Qian LL, Wang N, Qi MM, Zhang YM, Dang SP, Wu Y, Wang RX. Molecular Mechanisms of Glucose Fluctuations on Diabetic Complications. Frontiers in Endocrinology. 10: 640. PMID 31620092 DOI: 10.3389/fendo.2019.00640   
2019 Mohler K, Rinehart J. Expression of authentic post-translationally modified proteins in organisms with expanded genetic codes. Methods in Enzymology. 626: 539-559. PMID 31606090 DOI: 10.1016/bs.mie.2019.07.017   
2019 Joshi MK, Burton RA, Wu H, Lipchik AM, Craddock BP, Mo H, Parker LL, Miller WT, Post CB. Substrate binding to Src: a new perspective on tyrosine kinase substrate recognition from NMR and molecular dynamics. Protein Science : a Publication of the Protein Society. PMID 31697410 DOI: 10.1002/pro.3777   
2019 Yamazaki H, Kosako H, Yoshimura SH. Quantitative proteomics indicate a strong correlation of mitotic phospho-/dephosphorylation with non-structured regions of substrates. Biochimica Et Biophysica Acta. Proteins and Proteomics. 1868: 140295. PMID 31676455 DOI: 10.1016/j.bbapap.2019.140295   
2019 Kall SL, Whitlatch K, Smithgall TE, Lavie A. Molecular basis for the interaction between human choline kinase alpha and the SH3 domain of the c-Src tyrosine kinase. Scientific Reports. 9: 17121. PMID 31745227 DOI: 10.1038/s41598-019-53447-0   
2019 Strasser SD, Ghazi PC, Starchenko A, Boukhali M, Edwards A, Suarez-Lopez L, Lyons J, Changelian PS, Monahan JB, Jacobsen J, Brubaker DK, Joughin BA, Yaffe MB, Haas W, Lauffenburger DA, et al. Substrate-based kinase activity inference identifies MK2 as driver of colitis. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 31617572 DOI: 10.1093/intbio/zyz025   
2019 Li J, Paulo JA, Nusinow DP, Huttlin EL, Gygi SP. Investigation of Proteomic and Phosphoproteomic Responses to Signaling Network Perturbations Reveals Functional Pathway Organizations in Yeast. Cell Reports. 29: 2092-2104.e4. PMID 31722220 DOI: 10.1016/j.celrep.2019.10.034   
2019 de Souza VB, Kawano DF. Structural basis for the design of allosteric inhibitors of the Aurora kinase A enzyme in the cancer chemotherapy. Biochimica Et Biophysica Acta. General Subjects. 129448. PMID 31676293 DOI: 10.1016/j.bbagen.2019.129448   
2019 Ye J, Cheung J, Gerbino V, Ahlsén G, Zimanyi C, Hirsh D, Maniatis T. Effects of ALS-associated TANK binding kinase 1 mutations on protein-protein interactions and kinase activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 31748271 DOI: 10.1073/pnas.1915732116   
2019 Jia H, Song G, Werth EG, Walley JW, Hicks LM, Jones AM. Receptor-Like Kinase Phosphorylation of Arabidopsis Heterotrimeric G-Protein Gα -Subunit AtGPA1. Proteomics. e1900265. PMID 31693794 DOI: 10.1002/pmic.201900265   
2019 Halawa AH, Eskandrani AA, Elgammal WE, Hassan SM, Hassan AH, Ebrahim HY, Mehany ABM, El-Agrody AM, Okasha RM. Rational Design and Synthesis of Diverse Pyrimidine Molecules Bearing Sulfonamide Moiety as Novel ERK Inhibitors. International Journal of Molecular Sciences. 20. PMID 31717402 DOI: 10.3390/ijms20225592   
2019 Szymczak LC, Sykora DJ, Mrksich M. Using peptide arrays to profile phosphatase activity in cell lysates. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31691395 DOI: 10.1002/chem.201904364   
2019 Verma NK, Chalasani MLS, Scott JD, Kelleher D. CG-NAP/Kinase Interactions Fine-Tune T Cell Functions. Frontiers in Immunology. 10: 2642. PMID 31781123 DOI: 10.3389/fimmu.2019.02642   
2019 Astl L, Tse A, Verkhivker GM. Interrogating Regulatory Mechanisms in Signaling Proteins by Allosteric Inhibitors and Activators: A Dynamic View Through the Lens of Residue Interaction Networks. Advances in Experimental Medicine and Biology. 1163: 187-223. PMID 31707705 DOI: 10.1007/978-981-13-8719-7_9   
2019 Lopez ED, Burastero O, Arcon JP, Defelipe LA, Ahn NG, Marti MA, Turjanski AG. Kinase activation by small conformational changes. Journal of Chemical Information and Modeling. PMID 31714778 DOI: 10.1021/acs.jcim.9b00782   
2019 Zecchini S, Giovarelli M, Perrotta C, Morisi F, Touvier T, Di Renzo I, Moscheni C, Bassi MT, Cervia D, Sandri M, Clementi E, De Palma C. Autophagy controls neonatal myogenesis by regulating the GH-IGF1 system through a NFE2L2- and DDIT3-mediated mechanism. Autophagy. 15: 58-77. PMID 30081710 DOI: 10.1080/15548627.2018.1507439   
2019 Stein BD, Calzolari D, Hellberg K, Hu YS, He L, Hung CM, Toyama EQ, Ross DS, Lillemeier BF, Cantley LC, Yates JR, Shaw RJ. Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks. Cell Reports. 29: 3331-3348.e7. PMID 31801093 DOI: 10.1016/j.celrep.2019.10.117   
2019 Garg M, Wahid M, Khan F. Regulation of peripheral and central immunity: Understanding the role of Src homology 2 domain-containing tyrosine phosphatases, SHP-1 & SHP-2. Immunobiology. PMID 31561841 DOI: 10.1016/j.imbio.2019.09.006   
2019 Min X, Zhang X, Sun N, Acharya S, Kim KM. Mdm2-mediated ubiquitination of PKCβII in the nucleus mediates clathrin-mediated endocytic activity. Biochemical Pharmacology. 113675. PMID 31634457 DOI: 10.1016/j.bcp.2019.113675   
2019 Shi T, Yao L, Han Y, Hao P, Lu P. Quantitative Phosphoproteomics Reveals System-Wide Phosphorylation Network Altered by Spry in Mouse Mammary Stromal Fibroblasts. International Journal of Molecular Sciences. 20. PMID 31671542 DOI: 10.3390/ijms20215400   
2019 Sonntag T, Moresco JJ, Yates JR, Montminy M. The KLDpT activation loop motif is critical for MARK kinase activity. Plos One. 14: e0225727. PMID 31794565 DOI: 10.1371/journal.pone.0225727   
2019 Patel AL, Yeung E, McGuire SE, Wu AY, Toettcher JE, Burdine RD, Shvartsman SY. Optimizing photoswitchable MEK. Proceedings of the National Academy of Sciences of the United States of America. PMID 31796593 DOI: 10.1073/pnas.1912320116   
2019 Kritmetapak K, Kumar R. Phosphate as a Signaling Molecule. Calcified Tissue International. PMID 31768576 DOI: 10.1007/s00223-019-00636-8   
2019 Kanev GK, de Graaf C, de Esch IJP, Leurs R, Würdinger T, Westerman BA, Kooistra AJ. The Landscape of Atypical and Eukaryotic Protein Kinases. Trends in Pharmacological Sciences. 40: 818-832. PMID 31677919 DOI: 10.1016/   
2019 Von Achenbach C, Weller M, Kaulich K, Gramatzki D, Zacher A, Fabbro D, Reifenberger G, Szabó E. Synergistic growth inhibition mediated by dual PI3K/mTOR pathway targeting and genetic or direct pharmacological AKT inhibition in human glioblastoma models. Journal of Neurochemistry. PMID 31618458 DOI: 10.1111/jnc.14899   
2019 Wu Z, Jin Y, Chen B, Gugger MK, Wilkinson-Johnson CL, Tiambeng TN, Jin S, Ge Y. Comprehensive Characterization of the Recombinant Catalytic Subunit of cAMP-Dependent Protein Kinase by Top-Down Mass Spectrometry. Journal of the American Society For Mass Spectrometry. PMID 31792770 DOI: 10.1007/s13361-019-02341-0   
2019 Abbas MN, Kausar S, Zhao E, Cui H. Suppressors of cytokine signaling proteins as modulators of development and innate immunity of insects. Developmental and Comparative Immunology. 103561. PMID 31785267 DOI: 10.1016/j.dci.2019.103561   
2019 Oh JH, Karadeniz F, Lee JI, Seo Y, Kong CS. Inhibits Adipogenic Differentiation of 3T3-L1 Pre-Adipocytes via Downregulation of PPARγ and MAPK Pathways. Preventive Nutrition and Food Science. 24: 299-307. PMID 31608255 DOI: 10.3746/pnf.2019.24.3.299   
2019 Kruk M, Widstrom N, Jena S, Wolter NL, Blankenhorn JF, Abdalla I, Yang TY, Parker LL. Assays for tyrosine phosphorylation in human cells. Methods in Enzymology. 626: 375-406. PMID 31606083 DOI: 10.1016/bs.mie.2019.06.026   
2019 Huang S, Benben A, Green R, Cheranda N, Lee G, Joseph B, Keaveney S, Wang Y. Phosphorylation of the Gα protein Gpa2 promotes protein kinase A signaling in yeast. The Journal of Biological Chemistry. PMID 31690628 DOI: 10.1074/jbc.RA119.009609   
2019 Bui HTN, Niederwieser I, Bird MJ, Dai W, Brancucci NMB, Moes S, Jenoe P, Lucet IS, Doerig C, Voss TS. Mapping and functional analysis of heterochromatin protein 1 phosphorylation in the malaria parasite Plasmodium falciparum. Scientific Reports. 9: 16720. PMID 31723180 DOI: 10.1038/s41598-019-53325-9   
2019 Jin K, Wang B, Ruan ZB, Chen GC, Ren Y. Effect of miR-497 on myocardial cell apoptosis in rats with myocardial ischemia/reperfusion through the MAPK/ERK signaling pathway. European Review For Medical and Pharmacological Sciences. 23: 8580-8587. PMID 31646591 DOI: 10.26355/eurrev_201910_19174   
2019 Anaruma CP, Pereira RM, Cristina da Cruz Rodrigues K, Ramos da Silva AS, Cintra DE, Ropelle ER, Pauli JR, Pereira de Moura L. Rock protein as cardiac hypertrophy modulator in obesity and physical exercise. Life Sciences. 116955. PMID 31626788 DOI: 10.1016/j.lfs.2019.116955   
2019 Kruglova NA, Kopylov AT, Filatov AV. [Identification of the Molecular Partners of Lymphocyte Phosphatase-Associated Phosphoprotein (LPAP) That Are Involved in Human Lymphocyte Activation]. Molekuliarnaia Biologiia. 53: 838-848. PMID 31661482 DOI: 10.1134/S0026898419050112   
2019 Tan L, Bogush N, Naib H, Perry J, Calvert JW, Martin DIK, Graham RM, Naqvi N, Husain A. Redox activation of JNK2α2 mediates thyroid hormone-stimulated proliferation of neonatal murine cardiomyocytes. Scientific Reports. 9: 17731. PMID 31776360 DOI: 10.1038/s41598-019-53705-1   
2019 Majdi A, Aoudjehane L, Ratziu V, Islam T, Afonso MB, Conti F, Mestiri T, Lagouge M, Foufelle F, Ballenghien F, Ledent T, Moldes M, Cadoret A, Fouassier L, Delaunay JL, et al. Inhibition of receptor-interacting protein kinase 1 improves experimental non-alcoholic fatty liver disease. Journal of Hepatology. PMID 31760070 DOI: 10.1016/j.jhep.2019.11.008   
2019 Meant A, Gao B, Lavoie G, Nourreddine S, Jung F, Aubert L, Tcherkezian J, Gingras AC, Roux PP. Proteomic analysis reveals a role for RSK in p120-catenin phosphorylation and melanoma cell-cell adhesion. Molecular & Cellular Proteomics : McP. PMID 31678930 DOI: 10.1074/mcp.RA119.001811   
2019 Kim H, Jang JH, Song YE, Seo T. Kaposi's sarcoma-associated herpesvirus viral protein kinase phosphorylates extracellular signal-regulated kinase and activates MAPK/ERK signaling pathway. Biochemical and Biophysical Research Communications. PMID 31733836 DOI: 10.1016/j.bbrc.2019.11.038   
2019 Profeta GS, Dos Reis CV, Santiago ADS, Godoi PHC, Fala AM, Wells CI, Sartori R, Salmazo APT, Ramos PZ, Massirer KB, Elkins JM, Drewry DH, Gileadi O, Couñago RM. Binding and structural analyses of potent inhibitors of the human Ca/calmodulin dependent protein kinase kinase 2 (CAMKK2) identified from a collection of commercially-available kinase inhibitors. Scientific Reports. 9: 16452. PMID 31712618 DOI: 10.1038/s41598-019-52795-1