Jennifer E. Golden - Publications

University of Kansas, Lawrence, KS, United States 
 2015- Pharmaceutical Sciences Division, School of Pharmacy University of Wisconsin, Madison, Madison, WI 

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Skidmore AM, Adcock RS, Jonsson CB, Golden JE, Chung DH. Benzamidine ML336 inhibits plus and minus strand RNA synthesis of Venezuelan equine encephalitis virus without affecting host RNA production. Antiviral Research. 104674. PMID 31816348 DOI: 10.1016/j.antiviral.2019.104674  1
2019 Khalifa MM, Philkhana SC, Golden JE. Synthesis of Ring-Fused, N-Substituted 4-Quinolinones Using pKa-Guided, Base-Promoted Annulations with Isatoic Anhydrides: Total Synthesis of Penicinotam. The Journal of Organic Chemistry. PMID 31786917 DOI: 10.1021/acs.joc.9b02541  0.48
2019 Jonsson CB, Cao X, Lee J, Gabbard JD, Chu YK, Fitzpatrick EA, Julander J, Chung DH, Stabenow J, Golden JE. Efficacy of a ML336 derivative against Venezuelan and eastern equine encephalitis viruses. Antiviral Research. PMID 30970271 DOI: 10.1016/j.antiviral.2019.04.004  1
2019 Milanes JE, Suryadi J, Abendroth J, Van Voorhis WC, Barrett KF, Dranow DM, Phan IQ, Patrick SL, Rozema SD, Khalifa MM, Golden JE, Morris JC. Enzymatic and structural characterization of the glucokinase. Antimicrobial Agents and Chemotherapy. PMID 30783001 DOI: 10.1128/AAC.02410-18  1
2019 Jaffett VA, Nerurkar A, Cao X, Guzei IA, Golden JE. Telescoped synthesis of C3-functionalized (E)-arylamidines using Ugi-Mumm and regiospecific quinazolinone rearrangements. Organic & Biomolecular Chemistry. PMID 30730519 DOI: 10.1039/c9ob00073a  1
2018 Rinis N, Golden JE, Marceau CD, Carette JE, Van Zandt MC, Gilmore R, Contessa JN. Editing N-Glycan Site Occupancy with Small-Molecule Oligosaccharyltransferase Inhibitors. Cell Chemical Biology. PMID 30078634 DOI: 10.1016/j.chembiol.2018.07.005  1
2018 Yan G, Golden JE. Palladium-Catalyzed Cyclocarbonylation of Pyridinylated Vinylogous Amides and Ureas to Generate Ring-Fused Pyridopyrimidinones. Organic Letters. PMID 30009610 DOI: 10.1021/acs.orglett.8b01275  1
2017 Flaherty DP, Harris MT, Schroeder CE, Khan H, Kahney E, Hackler A, Patrick S, Weiner WS, Aube J, Sharlow ER, Morris JC, Golden JE. Optimization and Evaluation of Antiparasitic Benzamidobenzoic Acids as Inhibitors of Kinetoplastid Hexokinase 1. Chemmedchem. PMID 29105342 DOI: 10.1002/cmdc.201700592  1
2017 Gordhan HM, Milanes JE, Qiu Y, Golden JE, Christensen KA, Morris JC, Whitehead DC. A targeted delivery strategy for the development of potent trypanocides. Chemical Communications (Cambridge, England). PMID 28726862 DOI: 10.1039/c7cc03378h  1
2017 Hackler A, Patrick SL, Kahney EW, Flaherty DP, Sharlow ER, Morris JC, Golden JE. Antiparasitic lethality of sulfonamidebenzamides in kinetoplastids. Bioorganic & Medicinal Chemistry Letters. PMID 28119024 DOI: 10.1016/j.bmcl.2017.01.043  1
2016 Gordhan HM, Patrick SL, Swasy MI, Hackler AL, Anayee M, Golden JE, Morris JC, Whitehead DC. Evaluation of substituted ebselen derivatives as potential trypanocidal agents. Bioorganic & Medicinal Chemistry Letters. PMID 28043795 DOI: 10.1016/j.bmcl.2016.12.021  1
2016 Adcock RS, Chu YK, Golden JE, Chung DH. Evaluation of anti-Zika virus activities of broad-spectrum antivirals and NIH clinical collection compounds using a cell-based, high-throughput screen assay. Antiviral Research. PMID 27919709 DOI: 10.1016/j.antiviral.2016.11.018  1
2016 Lopez-Sambrooks C, Shrimal S, Khodier C, Flaherty DP, Rinis N, Charest JC, Gao N, Zhao P, Wells L, Lewis TA, Lehrman MA, Gilmore R, Golden JE, Contessa JN. Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells. Nature Chemical Biology. PMID 27694802 DOI: 10.1038/nchembio.2194  1
2016 Swingle M, Volmar CH, Saldanha SA, Chase P, Eberhart C, Salter EA, D'Arcy B, Schroeder CE, Golden JE, Wierzbicki A, Hodder P, Honkanen RE. An Ultra-High-Throughput Screen for Catalytic Inhibitors of Serine/Threonine Protein Phosphatases Types 1 and 5 (PP1C and PP5C). Journal of Biomolecular Screening. PMID 27628691 DOI: 10.1177/1087057116668852  1
2016 Davis MI, Patrick S, Blanding WM, Dwivedi V, Suryadi J, Golden JE, Coussens NP, Lee OW, Shen M, Boxer MB, Hall MD, Sharlow ER, Drew ME, Morris JC. Identification of Novel Plasmodium falciparum Hexokinase Inhibitors with Anti-parasitic Activity. Antimicrobial Agents and Chemotherapy. PMID 27458230 DOI: 10.1128/AAC.00914-16  1
2016 Weisshaar M, Cox R, Morehouse Z, Kyasa S, Yan D, Oberacker P, Mao S, Golden JE, Lowen AC, Natchus MG, Plemper RK. Identification and Characterization of Influenza Virus Entry Inhibitors Through Dual-Myxovirus High-Throughput Screening. Journal of Virology. PMID 27252534 DOI: 10.1128/JVI.00898-16  1
2016 Chung DH, Golden JE, Adcock RS, Schroeder CE, Chu YK, Sotsky JB, Cramer DE, Chilton PM, Song C, Anantpadma M, Davey RA, Prodhan AI, Yin X, Zhang X. Discovery of a broad-spectrum antiviral compound that inhibits pyrimidine biosynthesis and establishes a type 1 interferon-independent antiviral state. Antimicrobial Agents and Chemotherapy. PMID 27185801 DOI: 10.1128/AAC.00282-16  1
2016 Schroeder CE, Neuenswander SA, Yao T, Aubé J, Golden JE. One-pot, regiospecific assembly of (E)-benzamidines from δ- and γ-amino acids via an intramolecular aminoquinazolinone rearrangement. Organic & Biomolecular Chemistry. PMID 27050086 DOI: 10.1039/c5ob02378e  1
2016 Chattopadhyay D, Swingle MR, Salter EA, Wood E, D'Arcy B, Zivanov C, Abney K, Musiyenko A, Rusin SF, Kettenbach A, Yet L, Schroeder CE, Golden JE, Dunham WH, Gingras AC, et al. Crystal Structures and Mutagenesis of PPP-family ser/thr Protein Phosphatases Elucidate the Selectivity of Cantharidin and Novel Norcantharidin-based Inhibitors of PP5C. Biochemical Pharmacology. PMID 27002182 DOI: 10.1016/j.bcp.2016.03.011  1
2015 Hong L, Guo Y, BasuRay S, Agola JO, Romero E, Simpson DS, Schroeder CE, Simons P, Waller A, Garcia M, Carter M, Ursu O, Gouveia K, Golden JE, Aubé J, et al. A Pan-GTPase Inhibitor as a Molecular Probe. Plos One. 10: e0134317. PMID 26247207 DOI: 10.1371/journal.pone.0134317  1
2015 Schreiber SL, Kotz JD, Li M, Aubé J, Austin CP, Reed JC, Rosen H, White EL, Sklar LA, Lindsley CW, Alexander BR, Bittker JA, Clemons PA, de Souza A, Foley MA, ... ... Golden JE, et al. Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes. Cell. 161: 1252-1265. PMID 26046436 DOI: 10.1016/j.cell.2015.05.023  1
2014 Wender PA, Axtman AD, Golden JE, Kee JM, Sirois LE, Quiroz RV, Stevens MC. Function through bio-inspired, synthesis-informed design: step-economical syntheses of designed kinase inhibitors†Dedicated to Max Malacria, a friend and scholar whose science and creative contributions to step-economical synthesis have inspired us all and moved the field closer to the ideal.‡Electronic supplementary information (ESI) available: Synthetic procedures and spectral data. See DOI: 10.1039/c4qo00228hClick here for additional data file. Organic Chemistry Frontiers : An International Journal of Organic Chemistry / Royal Society of Chemistry. 1: 1166-1171. PMID 25632347 DOI: 10.1039/c4qo00228h  1
2014 Flaherty DP, Miller JR, Garshott DM, Hedrick M, Gosalia P, Li Y, Milewski M, Sugarman E, Vasile S, Salaniwal S, Su Y, Smith LH, Chung TD, Pinkerton AB, Aubé J, ... ... Golden JE, et al. Discovery of Sulfonamidebenzamides as Selective Apoptotic CHOP Pathway Activators of the Unfolded Protein Response. Acs Medicinal Chemistry Letters. 5: 1278-1283. PMID 25530830 DOI: 10.1021/ml5003234  1
2014 Matharu DS, Flaherty DP, Simpson DS, Schroeder CE, Chung D, Yan D, Noah JW, Jonsson CB, White EL, Aubé J, Plemper RK, Severson WE, Golden JE. Optimization of potent and selective quinazolinediones: inhibitors of respiratory syncytial virus that block RNA-dependent RNA-polymerase complex activity. Journal of Medicinal Chemistry. 57: 10314-28. PMID 25399509 DOI: 10.1021/jm500902x  1
2014 Schroeder CE, Yao T, Sotsky J, Smith RA, Roy S, Chu YK, Guo H, Tower NA, Noah JW, McKellip S, Sosa M, Rasmussen L, Smith LH, White EL, Aubé J, ... ... Golden JE, et al. Development of (E)-2-((1,4-dimethylpiperazin-2-ylidene)amino)-5-nitro-N-phenylbenzamide, ML336: Novel 2-amidinophenylbenzamides as potent inhibitors of venezuelan equine encephalitis virus. Journal of Medicinal Chemistry. 57: 8608-21. PMID 25244572 DOI: 10.1021/jm501203v  1
2014 Flaherty DP, Simpson DS, Miller M, Maki BE, Zou B, Shi J, Wu M, McManus OB, Aubé J, Li M, Golden JE. Potent and selective inhibitors of the TASK-1 potassium channel through chemical optimization of a bis-amide scaffold. Bioorganic & Medicinal Chemistry Letters. 24: 3968-73. PMID 25017033 DOI: 10.1016/j.bmcl.2014.06.032  1
2014 Chung DH, Jonsson CB, Tower NA, Chu YK, Sahin E, Golden JE, Noah JW, Schroeder CE, Sotsky JB, Sosa MI, Cramer DE, McKellip SN, Rasmussen L, White EL, Schmaljohn CS, et al. Discovery of a novel compound with anti-venezuelan equine encephalitis virus activity that targets the nonstructural protein 2. Plos Pathogens. 10: e1004213. PMID 24967809 DOI: 10.1371/journal.ppat.1004213  1
2013 Harris MT, Walker DM, Drew ME, Mitchell WG, Dao K, Schroeder CE, Flaherty DP, Weiner WS, Golden JE, Morris JC. Interrogating a hexokinase-selected small-molecule library for inhibitors of Plasmodium falciparum hexokinase. Antimicrobial Agents and Chemotherapy. 57: 3731-7. PMID 23716053 DOI: 10.1128/AAC.00662-13  1
2013 Hong L, Kenney SR, Phillips GK, Simpson D, Schroeder CE, Nöth J, Romero E, Swanson S, Waller A, Strouse JJ, Carter M, Chigaev A, Ursu O, Oprea T, Hjelle B, ... Golden JE, et al. Characterization of a Cdc42 protein inhibitor and its use as a molecular probe. The Journal of Biological Chemistry. 288: 8531-43. PMID 23382385 DOI: 10.1074/jbc.M112.435941  1
2013 Chung DH, Moore BP, Matharu DS, Golden JE, Maddox C, Rasmussen L, Sosa MI, Ananthan S, White EL, Jia F, Jonsson CB, Severson WE. A cell based high-throughput screening approach for the discovery of new inhibitors of respiratory syncytial virus. Virology Journal. 10: 19. PMID 23302182 DOI: 10.1186/1743-422X-10-19  1
2013 Strouse JJ, Ivnitski-Steele I, Khawaja HM, Perez D, Ricci J, Yao T, Weiner WS, Schroeder CE, Simpson DS, Maki BE, Li K, Golden JE, Foutz TD, Waller A, Evangelisti AM, et al. A selective ATP-binding cassette subfamily G member 2 efflux inhibitor revealed via high-throughput flow cytometry. Journal of Biomolecular Screening. 18: 26-38. PMID 22923785 DOI: 10.1177/1087057112456875  1
2012 Moore BP, Chung DH, Matharu DS, Golden JE, Maddox C, Rasmussen L, Noah JW, Sosa MI, Ananthan S, Tower NA, White EL, Jia F, Prisinzano TE, Aubé J, Jonsson CB, et al. (S)-N-(2,5-Dimethylphenyl)-1-(quinoline-8-ylsulfonyl)pyrrolidine-2-carboxamide as a small molecule inhibitor probe for the study of respiratory syncytial virus infection. Journal of Medicinal Chemistry. 55: 8582-7. PMID 23043370 DOI: 10.1021/jm300612z  1
2012 Agola JO, Hong L, Surviladze Z, Ursu O, Waller A, Strouse JJ, Simpson DS, Schroeder CE, Oprea TI, Golden JE, Aubé J, Buranda T, Sklar LA, Wandinger-Ness A. A competitive nucleotide binding inhibitor: in vitro characterization of Rab7 GTPase inhibition. Acs Chemical Biology. 7: 1095-108. PMID 22486388 DOI: 10.1021/cb3001099  1
2012 Chen J, Young SM, Allen C, Seeber A, Péli-Gulli MP, Panchaud N, Waller A, Ursu O, Yao T, Golden JE, Strouse JJ, Carter MB, Kang H, Bologa CG, Foutz TD, et al. Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry. Acs Chemical Biology. 7: 715-22. PMID 22260433 DOI: 10.1021/cb200452r  1
2012 Seguin SP, Evans CW, Nebane-Akah M, McKellip S, Ananthan S, Tower NA, Sosa M, Rasmussen L, White EL, Maki BE, Matharu DS, Golden JE, Aubé J, Brodsky JL, Noah JW. High-throughput screening identifies a bisphenol inhibitor of SV40 large T antigen ATPase activity. Journal of Biomolecular Screening. 17: 194-203. PMID 21948801 DOI: 10.1177/1087057111421630  1
2008 Frankowski KJ, Golden JE, Zeng Y, Lei Y, Aubé J. Syntheses of the Stemona alkaloids (+/-)-stenine, (+/-)-neostenine, and (+/-)-13-epineostenine using a stereodivergent Diels-Alder/azido-Schmidt reaction. Journal of the American Chemical Society. 130: 6018-24. PMID 18396881 DOI: 10.1021/ja800574m  1
2005 Lei Y, Wrobleski AD, Golden JE, Powell DR, Aubé J. Facile C-N cleavage in a series of bridged lactams. Journal of the American Chemical Society. 127: 4552-3. PMID 15796502 DOI: 10.1021/ja050214m  1
2002 Golden JE, Aubé J. A combined intramolecular Diels-Alder/intramolecular schmidt reaction: formal synthesis of (+/-)-stenine. Angewandte Chemie (International Ed. in English). 41: 4316-8. PMID 12434374 DOI: 10.1002/1521-3773(20021115)41:22<4316::AID-ANIE4316>3.0.CO;2-U  1
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