| Year |
Citation |
Score |
| 2023 |
Lee J, Wellenstein K, Rahnavard A, Nelson AT, Holter MM, Cummings B, Yeliseyev V, Castoldi A, Clish CB, Bry L, Siegel D, Kahn BB. Beneficial metabolic effects of PAHSAs depend on the gut microbiota in diet-induced obese mice. Biorxiv : the Preprint Server For Biology. PMID 37808673 DOI: 10.1101/2023.09.28.558803 |
0.377 |
|
| 2023 |
Santoro A, Kahn BB. Adipocyte Regulation of Insulin Sensitivity and the Risk of Type 2 Diabetes. The New England Journal of Medicine. 388: 2071-2085. PMID 37256977 DOI: 10.1056/NEJMra2216691 |
0.337 |
|
| 2022 |
Rubin de Celis MF, Garcia-Martin R, Syed I, Lee J, Aguayo-Mazzucato C, Bonner-Weir S, Kahn BB. PAHSAs reduce cellular senescence and protect pancreatic beta cells from metabolic stress through regulation of Mdm2/p53. Proceedings of the National Academy of Sciences of the United States of America. 119: e2206923119. PMID 36375063 DOI: 10.1073/pnas.2206923119 |
0.695 |
|
| 2022 |
Patel R, Santoro A, Hofer P, Tan D, Oberer M, Nelson AT, Konduri S, Siegel D, Zechner R, Saghatelian A, Kahn BB. ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids. Nature. PMID 35676490 DOI: 10.1038/s41586-022-04787-x |
0.394 |
|
| 2021 |
Aryal P, Syed I, Lee J, Patel R, Nelson AT, Siegel D, Saghatelian A, Kahn BB. Distinct Biological Activities of Isomers from Different Families of Branched Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs). Journal of Lipid Research. 100108. PMID 34418413 DOI: 10.1016/j.jlr.2021.100108 |
0.767 |
|
| 2021 |
McMillin SL, Stanley EC, Weyrauch LA, Brault JJ, Kahn BB, Witczak CA. Insulin Resistance Is Not Sustained Following Denervation in Glycolytic Skeletal Muscle. International Journal of Molecular Sciences. 22. PMID 34066429 DOI: 10.3390/ijms22094913 |
0.42 |
|
| 2021 |
Santoro A, McGraw TE, Kahn BB. Insulin action in adipocytes, adipose remodeling, and systemic effects. Cell Metabolism. 33: 748-757. PMID 33826917 DOI: 10.1016/j.cmet.2021.03.019 |
0.437 |
|
| 2021 |
Lee J, Vijayakumar A, White PJ, Xu Y, Ilkayeva O, Lynch CJ, Newgard CB, Kahn BB. BCAA Supplementation in Mice with Diet-Induced Obesity Alters the Metabolome Without Impairing Glucose Homeostasis. Endocrinology. PMID 33765118 DOI: 10.1210/endocr/bqab062 |
0.415 |
|
| 2020 |
Moraes-Vieira PM, Yore MM, Sontheimer-Phelps A, Castoldi A, Norseen J, Aryal P, Simonyté Sjödin K, Kahn BB. Retinol binding protein 4 primes the NLRP3 inflammasome by signaling through Toll-like receptors 2 and 4. Proceedings of the National Academy of Sciences of the United States of America. PMID 33214151 DOI: 10.1073/pnas.2013877117 |
0.437 |
|
| 2020 |
Hall JA, Ramachandran D, Roh HC, DiSpirito JR, Belchior T, Zushin PH, Palmer C, Hong S, Mina AI, Liu B, Deng Z, Aryal P, Jacobs C, Tenen D, Brown CW, ... ... Kahn BB, et al. Obesity-Linked PPARγ S273 Phosphorylation Promotes Insulin Resistance through Growth Differentiation Factor 3. Cell Metabolism. PMID 32941798 DOI: 10.1016/J.Cmet.2020.08.016 |
0.526 |
|
| 2020 |
Kilicarslan M, de Weijer BA, Simonyté Sjödin K, Aryal P, Ter Horst KW, Cakir H, Romijn JA, Ackermans MT, Janssen IM, Berends FJ, van de Laar AW, Houdijk AP, Kahn BB, Serlie MJ. RBP4 increases lipolysis in human adipocytes and is associated with increased lipolysis and hepatic insulin resistance in obese women. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32167208 DOI: 10.1096/Fj.201901979Rr |
0.536 |
|
| 2020 |
Lee J, Rahnavard A, Wellenstein K, Nelson AT, Clish CB, Siegel D, Kahn B. 1938-P: The Gut Microbiota Is Critical for the Beneficial Metabolic Effects of Palmitic Acid Hydroxy Stearic Acids (PAHSAs) in Diet-Induced Obese Mice Diabetes. 69. DOI: 10.2337/Db20-1938-P |
0.482 |
|
| 2020 |
Santoro A, Zhou P, Zhu Y, Peroni OD, Nelson AT, Siegel D, Kahn B. 1832-P: Palmitic Acid Esters of Hydroxy Stearic Acids Reduce Endogenous Glucose Production through GPR43 Activation Diabetes. 69. DOI: 10.2337/Db20-1832-P |
0.518 |
|
| 2019 |
Zhou P, Santoro A, Peroni OD, Nelson AT, Saghatelian A, Siegel D, Kahn BB. PAHSAs enhance hepatic and systemic insulin sensitivity through direct and indirect mechanisms. The Journal of Clinical Investigation. PMID 31449056 DOI: 10.1172/Jci127092 |
0.567 |
|
| 2019 |
Syed I, Rubinde Celis MF, Mohan JF, Moraes-Vieira PM, Vijayakumar A, Nelson AT, Siegel D, Saghatelian A, Mathis D, Kahn BB. PAHSAs attenuate immune responses and promote β cell survival in autoimmune diabetic mice. The Journal of Clinical Investigation. 129. PMID 31380811 DOI: 10.1172/Jci122445 |
0.723 |
|
| 2019 |
Tan D, Ertunc ME, Konduri S, Zhang J, Pinto AM, Chu Q, Kahn BB, Siegel D, Saghatelian A. Discovery of FAHFA-containing Triacylglycerols and Their Metabolic Regulation. Journal of the American Chemical Society. PMID 31056915 DOI: 10.1021/Jacs.9B00045 |
0.359 |
|
| 2019 |
Kahn BB. Adipose Tissue, Inter-Organ Communication, and the Path to Type 2 Diabetes: The 2016 Banting Medal for Scientific Achievement Lecture. Diabetes. 68: 3-14. PMID 30573674 DOI: 10.2337/Dbi18-0035 |
0.587 |
|
| 2019 |
SYED I, DE CELIS MFR, MOHAN JF, MORAES-VIERIA PM, VIJAYAKUMAR A, NELSON AT, SIEGEL D, SAGHATELIAN A, MATHIS D, KAHN B. 361-OR: ER Stress Attenuation Is Involved in PAHSA-Induced Reduction of T1D in Nonobese Diabetic (NOD) Mice Diabetes. 68: 361-OR. DOI: 10.2337/Db19-361-Or |
0.702 |
|
| 2019 |
ZHOU P, SANTORO A, PERONI OD, NELSON AT, SAGHATELIAN A, SIEGEL D, KAHN B. 1846-P: The Insulin-Sensitizing Effects of Palmitic Acid Esters of Hydroxy Stearic Acids Involve Intertissue Communication Diabetes. 68: 1846-P. DOI: 10.2337/Db19-1846-P |
0.553 |
|
| 2018 |
Hammarstedt A, Syed I, Vijayakumar A, Eliasson B, Gogg S, Kahn BB, Smith U. Adipose tissue dysfunction is associated with low levels of the novel Palmitic Acid Hydroxystearic Acids. Scientific Reports. 8: 15757. PMID 30361530 DOI: 10.1038/S41598-018-34113-3 |
0.747 |
|
| 2018 |
Syed I, Lee J, Peroni OD, Yore MM, Moraes-Vieira PM, Santoro A, Wellenstein K, Smith U, McGraw TE, Saghatelian A, Kahn BB. Methodological Issues in Studying PAHSA Biology: Masking PAHSA Effects. Cell Metabolism. PMID 30244974 DOI: 10.1016/J.Cmet.2018.09.007 |
0.695 |
|
| 2018 |
Yang Q, Vijayakumar A, Kahn BB. Metabolites as regulators of insulin sensitivity and metabolism. Nature Reviews. Molecular Cell Biology. PMID 30104701 DOI: 10.1038/S41580-018-0044-8 |
0.527 |
|
| 2018 |
Kong X, Yao T, Zhou P, Kazak L, Tenen D, Lyubetskaya A, Dawes BA, Tsai L, Kahn BB, Spiegelman BM, Liu T, Rosen ED. Brown Adipose Tissue Controls Skeletal Muscle Function via the Secretion of Myostatin. Cell Metabolism. PMID 30078553 DOI: 10.1016/J.Cmet.2018.07.004 |
0.311 |
|
| 2018 |
Kolar MJ, Nelson AT, Chang T, Ertunc ME, Christy MP, Ohlsson L, Härröd M, Kahn BB, Siegel D, Saghatelian A. Faster Protocol for Endogenous Fatty Acid Esters of Hydroxy Fatty Acid (FAHFA) Measurements. Analytical Chemistry. PMID 29578702 DOI: 10.1021/Acs.Analchem.8B00503 |
0.355 |
|
| 2018 |
Syed I, Lee J, Moraes-Vieira PM, Donaldson CJ, Sontheimer A, Aryal P, Wellenstein K, Kolar MJ, Nelson AT, Siegel D, Mokrosinski J, Farooqi IS, Zhao JJ, Yore MM, Peroni OD, ... ... Kahn BB, et al. Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis. Cell Metabolism. 27: 419-427.e4. PMID 29414687 DOI: 10.1016/J.Cmet.2018.01.001 |
0.796 |
|
| 2018 |
Okamoto S, Sato T, Tateyama M, Kageyama H, Maejima Y, Nakata M, Hirako S, Matsuo T, Kyaw S, Shiuchi T, Toda C, Sedbazar U, Saito K, Asgar NF, Zhang B, ... ... Kahn BB, et al. Activation of AMPK-Regulated CRH Neurons in the PVH is Sufficient and Necessary to Induce Dietary Preference for Carbohydrate over Fat. Cell Reports. 22: 706-721. PMID 29346768 DOI: 10.1016/J.Celrep.2017.11.102 |
0.31 |
|
| 2018 |
SANTORO A, ZHOU P, PERONI OD, SYED I, NELSON AT, SIEGEL D, SAGHATELIAN A, KAHN B. Palmitic Acid Esters of Hydroxy Stearic Acids Are Hepatic Insulin Sensitizers in Chow and High-Fat Diet (HFD)–Fed Mice Diabetes. 67: 1838-P. DOI: 10.2337/Db18-1838-P |
0.78 |
|
| 2017 |
Vijayakumar A, Aryal P, Wen J, Syed I, Vazirani RP, Moraes-Vieira PM, Camporez JP, Gallop MR, Perry RJ, Peroni OD, Shulman GI, Saghatelian A, McGraw TE, Kahn BB. Absence of Carbohydrate Response Element Binding Protein in Adipocytes Causes Systemic Insulin Resistance and Impairs Glucose Transport. Cell Reports. 21: 1021-1035. PMID 29069585 DOI: 10.1016/J.Celrep.2017.09.091 |
0.793 |
|
| 2017 |
Nelson AT, Kolar MJ, Chu Q, Syed I, Kahn BB, Saghatelian A, Siegel D. Stereochemistry of Endogenous Palmitic Acid Ester of 9-Hydroxystearic Acid and Relevance of Absolute Configuration to Regulation. Journal of the American Chemical Society. PMID 28350171 DOI: 10.1021/Jacs.7B01269 |
0.689 |
|
| 2017 |
McMillin SL, Schmidt DL, Kahn BB, Witczak CA. Glucose Transporter 4 (GLUT4) is Not Necessary for Overload-Induced Glucose Uptake or Hypertrophic Growth in Mouse Skeletal Muscle. Diabetes. PMID 28279980 DOI: 10.2337/Db16-1075 |
0.439 |
|
| 2017 |
Grünberg JR, Hoffmann JM, Hedjazifar S, Nerstedt A, Jenndahl L, Elvin J, Castellot J, Wei L, Movérare-Skrtic S, Ohlsson C, Holm LM, Bäckhed F, Syed I, Bosch F, Saghatelian A, ... Kahn BB, et al. Overexpressing the novel autocrine/endocrine adipokine WISP2 induces hyperplasia of the heart, white and brown adipose tissues and prevents insulin resistance. Scientific Reports. 7: 43515. PMID 28240264 DOI: 10.1038/Srep43515 |
0.771 |
|
| 2016 |
Reno CM, Puente EC, Sheng Z, Daphna-Iken D, Bree AJ, Routh VH, Kahn BB, Fisher SJ. Brain GLUT4 Knockout Mice Have Impaired Glucose Tolerance, Decreased Insulin Sensitivity, and Impaired Hypoglycemic Counterregulation. Diabetes. PMID 27797912 DOI: 10.2337/Db16-0917 |
0.511 |
|
| 2016 |
Smith U, Kahn BB. Adipose tissue regulates insulin sensitivity: role of adipogenesis, de novo lipogenesis and novel lipids. Journal of Internal Medicine. PMID 27699898 DOI: 10.1111/Joim.12540 |
0.566 |
|
| 2016 |
Lee J, Moraes-Vieira PM, Castoldi A, Aryal P, Yee EU, Vickers C, Parnas O, Donaldson CJ, Saghatelian A, Kahn BB. Branched fatty acid esters of hydroxy fatty acids (FAHFAs) protect against colitis by regulating the gut innate and adaptive immune systems. The Journal of Biological Chemistry. PMID 27573241 DOI: 10.1074/Jbc.M115.703835 |
0.325 |
|
| 2016 |
Kolar MJ, Kamat SS, Parsons WH, Homan EA, Maher T, Peroni OD, Syed I, Fjeld K, Molven A, Kahn BB, Cravatt BF, Saghatelian A. Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase. Biochemistry. PMID 27509211 DOI: 10.1021/Acs.Biochem.6B00565 |
0.692 |
|
| 2016 |
Moraes-Vieira PM, Saghatelian A, Kahn BB. GLUT4 Expression in Adipocytes Regulates De Novo Lipogenesis and Levels of a Novel Class of Lipids With Antidiabetic and Anti-inflammatory Effects. Diabetes. PMID 27288004 DOI: 10.2337/Db16-0221 |
0.56 |
|
| 2016 |
Lee SA, Yuen JJ, Jiang H, Kahn BB, Blaner WS. Adipocyte-specific over-expression of retinol-binding protein 4 (RBP4) causes hepatic steatosis in mice. Hepatology (Baltimore, Md.). PMID 27227735 DOI: 10.1002/Hep.28659 |
0.424 |
|
| 2016 |
Vazirani RP, Verma A, Sadacca LA, Buckman MS, Picatoste B, Beg M, Torsitano C, Bruno JH, Patel RT, Simonyte K, Camporez JP, Moreira G, Falcone DJ, Accili D, Elemento O, ... ... Kahn BB, et al. Disruption of Adipose Rab10-Dependent Insulin Signaling Causes Hepatic Insulin Resistance. Diabetes. PMID 27207531 DOI: 10.2337/db15-1128 |
0.468 |
|
| 2016 |
Zhang T, Chen S, Syed I, Ståhlman M, Kolar MJ, Homan EA, Chu Q, Smith U, Borén J, Kahn BB, Saghatelian A. A LC-MS-based workflow for measurement of branched fatty acid esters of hydroxy fatty acids. Nature Protocols. 11: 747-763. PMID 26985573 DOI: 10.1038/Nprot.2016.040 |
0.675 |
|
| 2016 |
Moraes-Vieira PM, Castoldi A, Aryal P, Wellenstein K, Peroni OD, Kahn BB. Antigen presentation and T cell activation are critical for RBP4-induced insulin resistance. Diabetes. PMID 26936962 DOI: 10.2337/Db15-1696 |
0.486 |
|
| 2016 |
Coughlan KA, Valentine RJ, Sudit BS, Allen K, Dagon Y, Kahn BB, Ruderman NB, Saha AK. PKD1 Inhibits AMPKα2 through Phosphorylation of Serine 491 and Impairs Insulin Signaling in Skeletal Muscle Cells. The Journal of Biological Chemistry. PMID 26797128 DOI: 10.1074/Jbc.M115.696849 |
0.414 |
|
| 2016 |
Lyons CL, Finucane OF, Murphy AM, Cooke AA, Viollet B, Vieira PM, Oldham W, Kahn BB, Roche HM. Monounsaturated Fatty Acids Impede Inflammation Partially Through Activation of AMPK The Faseb Journal. 30. DOI: 10.1096/Fasebj.30.1_Supplement.296.5 |
0.306 |
|
| 2015 |
Kraus BJ, Sartoretto JL, Polak P, Hosooka T, Shiroto T, Eskurza I, Lee SA, Jiang H, Michel T, Kahn BB. Novel role for retinol-binding protein 4 in the regulation of blood pressure. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 25911613 DOI: 10.1096/Fj.14-266064 |
0.348 |
|
| 2015 |
Dodd GT, Decherf S, Loh K, Simonds SE, Wiede F, Balland E, Merry TL, Münzberg H, Zhang ZY, Kahn BB, Neel BG, Bence KK, Andrews ZB, Cowley MA, Tiganis T. Leptin and insulin act on POMC neurons to promote the browning of white fat. Cell. 160: 88-104. PMID 25594176 DOI: 10.1016/J.Cell.2014.12.022 |
0.469 |
|
| 2015 |
Zemany L, Bhanot S, Peroni OD, Murray SF, Moraes-Vieira PM, Castoldi A, Manchem P, Guo S, Monia BP, Kahn BB. Transthyretin Antisense Oligonucleotides Lower Circulating RBP4 Levels and Improve Insulin Sensitivity in Obese Mice. Diabetes. 64: 1603-14. PMID 25524914 DOI: 10.2337/Db14-0970 |
0.558 |
|
| 2014 |
Prothiwa M, Syed I, Huising MO, van der Meulen T, Donaldson CJ, Trauger SA, Kahn BB, Saghatelian A. Data-driven synthesis of proteolysis-resistant peptide hormones. Journal of the American Chemical Society. 136: 17710-3. PMID 25496053 DOI: 10.1021/Ja5065735 |
0.723 |
|
| 2014 |
Yore MM, Syed I, Moraes-Vieira PM, Zhang T, Herman MA, Homan EA, Patel RT, Lee J, Chen S, Peroni OD, Dhaneshwar AS, Hammarstedt A, Smith U, McGraw TE, Saghatelian A, ... Kahn BB, et al. Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects. Cell. 159: 318-32. PMID 25303528 DOI: 10.1016/J.Cell.2014.09.035 |
0.798 |
|
| 2014 |
Chiappini F, Catalano KJ, Lee J, Peroni OD, Lynch J, Dhaneshwar AS, Wellenstein K, Sontheimer A, Neel BG, Kahn BB. Ventromedial hypothalamus-specific Ptpn1 deletion exacerbates diet-induced obesity in female mice. The Journal of Clinical Investigation. 124: 3781-92. PMID 25083988 DOI: 10.1172/Jci68585 |
0.481 |
|
| 2014 |
Kraus D, Yang Q, Kong D, Banks AS, Zhang L, Rodgers JT, Pirinen E, Pulinilkunnil TC, Gong F, Wang YC, Cen Y, Sauve AA, Asara JM, Peroni OD, Monia BP, ... ... Kahn BB, et al. Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity. Nature. 508: 258-62. PMID 24717514 DOI: 10.1038/Nature13198 |
0.437 |
|
| 2014 |
Moraes-Vieira PM, Yore MM, Dwyer PM, Syed I, Aryal P, Kahn BB. RBP4 activates antigen-presenting cells, leading to adipose tissue inflammation and systemic insulin resistance. Cell Metabolism. 19: 512-26. PMID 24606904 DOI: 10.1016/J.Cmet.2014.01.018 |
0.768 |
|
| 2014 |
Zemany L, Kraus BJ, Norseen J, Saito T, Peroni OD, Johnson RL, Kahn BB. Downregulation of STRA6 in adipocytes and adipose stromovascular fraction in obesity and effects of adipocyte-specific STRA6 knockdown in vivo. Molecular and Cellular Biology. 34: 1170-86. PMID 24421389 DOI: 10.1128/Mcb.01106-13 |
0.529 |
|
| 2014 |
Guzman J, Jauregui AN, Merscher-Gomez S, Maiguel D, Muresan C, Mitrofanova A, Diez-Sampedro A, Szust J, Yoo TH, Villarreal R, Pedigo C, Molano RD, Johnson K, Kahn B, Hartleben B, et al. Podocyte-specific GLUT4-deficient mice have fewer and larger podocytes and are protected from diabetic nephropathy. Diabetes. 63: 701-14. PMID 24101677 DOI: 10.2337/Db13-0752 |
0.398 |
|
| 2014 |
Kahn BB, Kraus D, Yang Q. Biguanide therapy for diabetes and cancer & a novel methyltransferase that regulates energy expenditure and adiposity and is elevated in many cancers Cancer and Metabolism. 2: 1-1. DOI: 10.1186/2049-3002-2-S1-O25 |
0.51 |
|
| 2013 |
Kahn BB, Minokoshi Y. Leptin, GABA, and glucose control Cell Metabolism. 18: 304-306. PMID 24011066 DOI: 10.1016/J.Cmet.2013.08.015 |
0.487 |
|
| 2013 |
Miraldi ER, Sharfi H, Friedline RH, Johnson H, Zhang T, Lau KS, Ko HJ, Curran TG, Haigis KM, Yaffe MB, Bonneau R, Lauffenburger DA, Kahn BB, Kim JK, Neel BG, et al. Molecular network analysis of phosphotyrosine and lipid metabolism in hepatic PTP1b deletion mice. Integrative Biology : Quantitative Biosciences From Nano to Macro. 5: 940-63. PMID 23685806 DOI: 10.1039/C3Ib40013A |
0.393 |
|
| 2013 |
Kurland IJ, Accili D, Burant C, Fischer SM, Kahn BB, Newgard CB, Ramagiri S, Ronnett GV, Ryals JA, Sanders M, Shambaugh J, Shockcor J, Gross SS. Application of combined omics platforms to accelerate biomedical discovery in diabesity. Annals of the New York Academy of Sciences. 1287: 1-16. PMID 23659636 DOI: 10.1111/Nyas.12116 |
0.309 |
|
| 2013 |
Sun Q, Kiernan UA, Shi L, Phillips DA, Kahn BB, Hu FB, Manson JE, Albert CM, Rexrode KM. Plasma retinol-binding protein 4 (RBP4) levels and risk of coronary heart disease: a prospective analysis among women in the nurses' health study. Circulation. 127: 1938-47. PMID 23584360 DOI: 10.1161/Circulationaha.113.002073 |
0.311 |
|
| 2013 |
Wu N, Zheng B, Shaywitz A, Dagon Y, Tower C, Bellinger G, Shen CH, Wen J, Asara J, McGraw TE, Kahn BB, Cantley LC. AMPK-dependent degradation of TXNIP upon energy stress leads to enhanced glucose uptake via GLUT1. Molecular Cell. 49: 1167-75. PMID 23453806 DOI: 10.1016/J.Molcel.2013.01.035 |
0.431 |
|
| 2013 |
Lee KY, Russell SJ, Ussar S, Boucher J, Vernochet C, Mori MA, Smyth G, Rourk M, Cederquist C, Rosen ED, Kahn BB, Kahn CR. Lessons on conditional gene targeting in mouse adipose tissue. Diabetes. 62: 864-74. PMID 23321074 DOI: 10.2337/Db12-1089 |
0.305 |
|
| 2012 |
Hammarstedt A, Graham TE, Kahn BB. Adipose tissue dysregulation and reduced insulin sensitivity in non-obese individuals with enlarged abdominal adipose cells. Diabetology & Metabolic Syndrome. 4: 42. PMID 22992414 DOI: 10.1186/1758-5996-4-42 |
0.519 |
|
| 2012 |
Kawashima J, Alquier T, Tsuji Y, Peroni OD, Kahn BB. Ca2+/calmodulin-dependent protein kinase kinase is not involved in hypothalamic amp-activated protein kinase activation by neuroglucopenia Plos One. 7. PMID 22590531 DOI: 10.1371/Journal.Pone.0036335 |
0.312 |
|
| 2012 |
Herman MA, Peroni OD, Villoria J, Schön MR, Abumrad NA, Blüher M, Klein S, Kahn BB. A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism. Nature. 484: 333-8. PMID 22466288 DOI: 10.1038/Nature10986 |
0.554 |
|
| 2012 |
Norseen J, Hosooka T, Hammarstedt A, Yore MM, Kant S, Aryal P, Kiernan UA, Phillips DA, Maruyama H, Kraus BJ, Usheva A, Davis RJ, Smith U, Kahn BB. Retinol-binding protein 4 inhibits insulin signaling in adipocytes by inducing proinflammatory cytokines in macrophages through a c-Jun N-terminal kinase- and toll-like receptor 4-dependent and retinol-independent mechanism. Molecular and Cellular Biology. 32: 2010-9. PMID 22431523 DOI: 10.1128/Mcb.06193-11 |
0.5 |
|
| 2012 |
Owen C, Czopek A, Agouni A, Grant L, Judson R, Lees EK, Mcilroy GD, Göransson O, Welch A, Bence KK, Kahn BB, Neel BG, Mody N, Delibegovi? M. Adipocyte-specific protein tyrosine phosphatase 1B deletion increases lipogenesis, adipocyte cell size and is a minor regulator of glucose homeostasis. Plos One. 7: e32700. PMID 22389718 DOI: 10.1371/Journal.Pone.0032700 |
0.567 |
|
| 2012 |
Yang Q, Eskurza I, Kiernan UA, Phillips DA, Blüher M, Graham TE, Kahn BB. Quantitative measurement of full-length and C-terminal proteolyzed RBP4 in serum of normal and insulin-resistant humans using a novel mass spectrometry immunoassay. Endocrinology. 153: 1519-27. PMID 22253430 DOI: 10.1210/En.2011-1750 |
0.488 |
|
| 2012 |
Kahn B, Herman MA, Peroni OD. Novel mechanisms by which fat cells regulate systemic insulin sensitivity and diabetes risk Bmc Proceedings. 6: 1-1. DOI: 10.1186/1753-6561-6-S3-O13 |
0.572 |
|
| 2012 |
Loh K, Fukushima A, Zhang X, Galic S, Briggs D, Enriori PJ, Simonds S, Wiede F, Reichenbach A, Hauser C, Sims NA, Bence KK, Zhang S, Zhang ZY, Kahn BB, et al. Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance (Cell Metabolism (2011) 14, (684-699)) Cell Metabolism. 15: 925-926. DOI: 10.1016/J.Cmet.2012.05.005 |
0.333 |
|
| 2011 |
Loh K, Fukushima A, Zhang X, Galic S, Briggs D, Enriori PJ, Simonds S, Wiede F, Reichenbach A, Hauser C, Sims NA, Bence KK, Zhang S, Zhang ZY, Kahn BB, et al. Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance. Cell Metabolism. 14: 684-99. PMID 22000926 DOI: 10.1016/J.Cmet.2011.09.011 |
0.378 |
|
| 2011 |
Noriega LG, Feige JN, Canto C, Yamamoto H, Yu J, Herman MA, Mataki C, Kahn BB, Auwerx J. CREB and ChREBP oppositely regulate SIRT1 expression in response to energy availability. Embo Reports. 12: 1069-76. PMID 21836635 DOI: 10.1038/Embor.2011.151 |
0.307 |
|
| 2011 |
Pulinilkunnil T, He H, Kong D, Asakura K, Peroni OD, Lee A, Kahn BB. Adrenergic regulation of AMP-activated protein kinase in brown adipose tissue in vivo. The Journal of Biological Chemistry. 286: 8798-809. PMID 21209093 DOI: 10.1074/Jbc.M111.218719 |
0.328 |
|
| 2010 |
Kahn BB, McGraw TE. Rosiglitazone, PPARγ, and type 2 diabetes. The New England Journal of Medicine. 363: 2667-9. PMID 21190462 DOI: 10.1056/Nejmcibr1012075 |
0.479 |
|
| 2010 |
Matsuo K, Delibegovic M, Matsuo I, Nagata N, Liu S, Bettaieb A, Xi Y, Araki K, Yang W, Kahn BB, Neel BG, Haj FG. Altered glucose homeostasis in mice with liver-specific deletion of Src homology phosphatase 2. The Journal of Biological Chemistry. 285: 39750-8. PMID 20841350 DOI: 10.1074/Jbc.M110.153734 |
0.537 |
|
| 2010 |
Yang Z, Kahn BB, Shi H, Xue BZ. Macrophage alpha1 AMP-activated protein kinase (alpha1AMPK) antagonizes fatty acid-induced inflammation through SIRT1. The Journal of Biological Chemistry. 285: 19051-9. PMID 20421294 DOI: 10.1074/Jbc.M110.123620 |
0.426 |
|
| 2010 |
Kraus D, Herman MA, Kahn BB. Leveraging leptin for type I diabetes? Proceedings of the National Academy of Sciences of the United States of America. 107: 4793-4. PMID 20212134 DOI: 10.1073/Pnas.1000736107 |
0.507 |
|
| 2010 |
Herman MA, She P, Peroni OD, Lynch CJ, Kahn BB. Adipose tissue branched chain amino acid (BCAA) metabolism modulates circulating BCAA levels. The Journal of Biological Chemistry. 285: 11348-56. PMID 20093359 DOI: 10.1074/Jbc.M109.075184 |
0.431 |
|
| 2010 |
Bence KK, Delibegovic M, Xue B, Gorgun CZ, Hotamisligil GS, Neel BG, Kahn BB. Erratum: Corrigendum: Neuronal PTP1B regulates body weight, adiposity and leptin action Nature Medicine. 16: 237-237. DOI: 10.1038/Nm0210-237A |
0.304 |
|
| 2009 |
Jourdan M, Jaleel A, Karakelides H, Ford GC, Kahn BB, Nair KS. Impact of type 1 diabetes and insulin treatment on plasma levels and fractional synthesis rate of retinol-binding protein 4. The Journal of Clinical Endocrinology and Metabolism. 94: 5125-30. PMID 19850685 DOI: 10.1210/Jc.2009-1331 |
0.495 |
|
| 2009 |
Preitner F, Mody N, Graham TE, Peroni OD, Kahn BB. Long-term Fenretinide treatment prevents high-fat diet-induced obesity, insulin resistance, and hepatic steatosis. American Journal of Physiology. Endocrinology and Metabolism. 297: E1420-9. PMID 19826103 DOI: 10.1152/Ajpendo.00362.2009 |
0.526 |
|
| 2009 |
Hill JW, Xu Y, Preitner F, Fukuda M, Cho YR, Luo J, Balthasar N, Coppari R, Cantley LC, Kahn BB, Zhao JJ, Elmquist JK. Phosphatidyl inositol 3-kinase signaling in hypothalamic proopiomelanocortin neurons contributes to the regulation of glucose homeostasis. Endocrinology. 150: 4874-82. PMID 19819947 DOI: 10.1210/En.2009-0454 |
0.451 |
|
| 2009 |
Liu J, Divoux A, Sun J, Zhang J, Clément K, Glickman JN, Sukhova GK, Wolters PJ, Du J, Gorgun CZ, Doria A, Libby P, Blumberg RS, Kahn BB, Hotamisligil GS, et al. Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice. Nature Medicine. 15: 940-5. PMID 19633655 DOI: 10.1038/Nm.1994 |
0.419 |
|
| 2009 |
Xue B, Pulinilkunnil T, Murano I, Bence KK, He H, Minokoshi Y, Asakura K, Lee A, Haj F, Furukawa N, Catalano KJ, Delibegovic M, Balschi JA, Cinti S, Neel BG, ... Kahn BB, et al. Neuronal protein tyrosine phosphatase 1B deficiency results in inhibition of hypothalamic AMPK and isoform-specific activation of AMPK in peripheral tissues. Molecular and Cellular Biology. 29: 4563-73. PMID 19528236 DOI: 10.1128/Mcb.01914-08 |
0.393 |
|
| 2009 |
Delibegovic M, Zimmer D, Kauffman C, Rak K, Hong EG, Cho YR, Kim JK, Kahn BB, Neel BG, Bence KK. Liver-specific deletion of protein-tyrosine phosphatase 1B (PTP1B) improves metabolic syndrome and attenuates diet-induced endoplasmic reticulum stress. Diabetes. 58: 590-9. PMID 19074988 DOI: 10.2337/Db08-0913 |
0.539 |
|
| 2009 |
Goodman E, Graham TE, Dolan LM, Daniels SR, Goodman ER, Kahn BB. The relationship of retinol binding protein 4 to changes in insulin resistance and cardiometabolic risk in overweight black adolescents. The Journal of Pediatrics. 154: 67-73.e1. PMID 18783798 DOI: 10.1016/J.Jpeds.2008.07.018 |
0.371 |
|
| 2009 |
Kennedy AR, Pissios P, Otu H, Roberson R, Xue B, Asakura K, Furukawa N, Marino FE, Liu FF, Kahn BB, Libermann TA, Maratos-Flier E. A high-fat, ketogenic diet induces a unique metabolic state in mice (American Journal of Physiology - Endocrinology and Metabolism (2007) 292, 55, (E1724-E1739)) American Journal of Physiology - Endocrinology and Metabolism. 296: E1179. DOI: 10.1152/Ajpendo.Zh1-05678-Corr-2009 |
0.307 |
|
| 2009 |
Gnudi L, Frevert EU, Houseknecht KL, Kahn BB. P-67: Use of recombinant adenovirus-mediated gene transfer to investigate the effects of dominant negative ras on the activation of PI3 kinase and glucose transport in 3T3L1 adipocytes Experimental and Clinical Endocrinology & Diabetes. 104: 132-133. DOI: 10.1055/S-0029-1211610 |
0.356 |
|
| 2009 |
Houseknecht KL, Flier SN, Frevert EU, Frederich RC, Flier JS, Kahn BB. O-2: Leptin secretion by the adipocyte: Regulation with genetic and dietary obesity and search for an intracellular storage pool Experimental and Clinical Endocrinology & Diabetes. 104: 8-8. DOI: 10.1055/S-0029-1211493 |
0.307 |
|
| 2008 |
Enjyoji K, Kotani K, Thukral C, Blumel B, Sun X, Wu Y, Imai M, Friedman D, Csizmadia E, Bleibel W, Kahn BB, Robson SC. Deletion of cd39/entpd1 results in hepatic insulin resistance. Diabetes. 57: 2311-20. PMID 18567823 DOI: 10.2337/Db07-1265 |
0.506 |
|
| 2008 |
Krzyzanowska K, Zemany L, Krugluger W, Schernthaner GH, Mittermayer F, Schnack C, Rahman R, Brix J, Kahn BB, Schernthaner G. Serum concentrations of retinol-binding protein 4 in women with and without gestational diabetes Diabetologia. 51: 1115-1122. PMID 18437353 DOI: 10.1007/S00125-008-1009-9 |
0.434 |
|
| 2008 |
Hammarstedt A, Pihlajamäki J, Graham TE, Kainulainen S, Kahn BB, Laakso M, Smith U. High circulating levels of RBP4 and mRNA levels of aP2, PGC-1alpha and UCP-2 predict improvement in insulin sensitivity following pioglitazone treatment of drug-naïve type 2 diabetic subjects. Journal of Internal Medicine. 263: 440-9. PMID 18324929 DOI: 10.1111/J.1365-2796.2007.01914.X |
0.403 |
|
| 2008 |
Mody N, Graham TE, Tsuji Y, Yang Q, Kahn BB. Decreased clearance of serum retinol-binding protein and elevated levels of transthyretin in insulin-resistant ob/ob mice. American Journal of Physiology. Endocrinology and Metabolism. 294: E785-93. PMID 18285525 DOI: 10.1152/Ajpendo.00521.2007 |
0.438 |
|
| 2008 |
Zabolotny JM, Kim YB, Welsh LA, Kershaw EE, Neel BG, Kahn BB. Protein-tyrosine phosphatase 1B expression is induced by inflammation in vivo. The Journal of Biological Chemistry. 283: 14230-41. PMID 18281274 DOI: 10.1074/Jbc.M800061200 |
0.475 |
|
| 2008 |
Dyck FV, Scroyen I, Declercq J, Sciot R, Kahn B, Lijnen R, Ven WVd. aP2-Cre-mediated expression activation of an oncogenic PLAG1 transgene results in cavernous angiomatosis in mice International Journal of Oncology. 32: 33-40. DOI: 10.3892/Ijo.32.1.33 |
0.34 |
|
| 2007 |
Graham TE, Kahn BB. Tissue-specific alterations of glucose transport and molecular mechanisms of intertissue communication in obesity and type 2 diabetes. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Mã©Tabolisme. 39: 717-21. PMID 17952832 DOI: 10.1055/S-2007-985879 |
0.571 |
|
| 2007 |
Kovacs P, Geyer M, Berndt J, Klöting N, Graham TE, Böttcher Y, Enigk B, Tönjes A, Schleinitz D, Schön MR, Kahn BB, Blüher M, Stumvoll M. Effects of genetic variation in the human retinol binding protein-4 gene (RBP4) on insulin resistance and fat depot-specific mRNA expression. Diabetes. 56: 3095-100. PMID 17728376 DOI: 10.2337/Db06-1647 |
0.428 |
|
| 2007 |
Delibegovic M, Bence KK, Mody N, Hong EG, Ko HJ, Kim JK, Kahn BB, Neel BG. Improved glucose homeostasis in mice with muscle-specific deletion of protein-tyrosine phosphatase 1B. Molecular and Cellular Biology. 27: 7727-34. PMID 17724080 DOI: 10.1128/Mcb.00959-07 |
0.56 |
|
| 2007 |
Yang M, Zhang Y, Pan J, Sun J, Liu J, Libby P, Sukhova GK, Doria A, Katunuma N, Peroni OD, Guerre-Millo M, Kahn BB, Clement K, Shi GP. Cathepsin L activity controls adipogenesis and glucose tolerance. Nature Cell Biology. 9: 970-7. PMID 17643114 DOI: 10.1038/Ncb1623 |
0.547 |
|
| 2007 |
Petersen KF, Dufour S, Savage DB, Bilz S, Solomon G, Yonemitsu S, Cline GW, Befroy D, Zemany L, Kahn BB, Papademetris X, Rothman DL, Shulman GI. The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome. Proceedings of the National Academy of Sciences of the United States of America. 104: 12587-94. PMID 17640906 DOI: 10.1073/Pnas.0705408104 |
0.455 |
|
| 2007 |
Yan QW, Yang Q, Mody N, Graham TE, Hsu CH, Xu Z, Houstis NE, Kahn BB, Rosen ED. The adipokine lipocalin 2 is regulated by obesity and promotes insulin resistance. Diabetes. 56: 2533-40. PMID 17639021 DOI: 10.2337/Db07-0007 |
0.406 |
|
| 2007 |
Klöting N, Graham TE, Berndt J, Kralisch S, Kovacs P, Wason CJ, Fasshauer M, Schön MR, Stumvoll M, Blüher M, Kahn BB. Serum retinol-binding protein is more highly expressed in visceral than in subcutaneous adipose tissue and is a marker of intra-abdominal fat mass. Cell Metabolism. 6: 79-87. PMID 17618858 DOI: 10.1016/J.Cmet.2007.06.002 |
0.45 |
|
| 2007 |
Xue B, Kim YB, Lee A, Toschi E, Bonner-Weir S, Kahn CR, Neel BG, Kahn BB. Protein-tyrosine phosphatase 1B deficiency reduces insulin resistance and the diabetic phenotype in mice with polygenic insulin resistance. The Journal of Biological Chemistry. 282: 23829-40. PMID 17545163 DOI: 10.1074/Jbc.M609680200 |
0.524 |
|
| 2007 |
Gray S, Wang B, Orihuela Y, Hong EG, Fisch S, Haldar S, Cline GW, Kim JK, Peroni OD, Kahn BB, Jain MK. Regulation of gluconeogenesis by Krüppel-like factor 15. Cell Metabolism. 5: 305-12. PMID 17403374 DOI: 10.1016/J.Cmet.2007.03.002 |
0.418 |
|
| 2007 |
Balagopal P, Graham TE, Kahn BB, Altomare A, Funanage V, George D. Reduction of elevated serum retinol binding protein in obese children by lifestyle intervention: association with subclinical inflammation. The Journal of Clinical Endocrinology and Metabolism. 92: 1971-4. PMID 17341558 DOI: 10.1210/Jc.2006-2712 |
0.313 |
|
| 2007 |
Kennedy AR, Pissios P, Otu H, Roberson R, Xue B, Asakura K, Furukawa N, Marino FE, Liu FF, Kahn BB, Libermann TA, Maratos-Flier E. A high-fat, ketogenic diet induces a unique metabolic state in mice. American Journal of Physiology. Endocrinology and Metabolism. 292: E1724-39. PMID 17299079 DOI: 10.1152/Ajpendo.00717.2006 |
0.36 |
|
| 2007 |
Graham TE, Wason CJ, Blüher M, Kahn BB. Shortcomings in methodology complicate measurements of serum retinol binding protein (RBP4) in insulin-resistant human subjects. Diabetologia. 50: 814-23. PMID 17294166 DOI: 10.1007/S00125-006-0557-0 |
0.474 |
|
| 2007 |
Alquier T, Kawashima J, Tsuji Y, Kahn BB. Role of hypothalamic adenosine 5'-monophosphate-activated protein kinase in the impaired counterregulatory response induced by repetitive neuroglucopenia. Endocrinology. 148: 1367-75. PMID 17185376 DOI: 10.1210/En.2006-1039 |
0.353 |
|
| 2007 |
Kennedy AR, Pissios P, Otu HH, Xue B, Asakura K, Furukawa N, Marino FE, Liu FF, Kahn BB, Libermann TA, Maratos-Flier E. Erratum: A high-fat, ketogenic diet induces a unique metabolic state in mice (American Journal of Physiology - Endocrinology and Metabolism doi 10.1152/ajpendo.00717.2006) American Journal of Physiology-Endocrinology and Metabolism. 293. DOI: 10.1152/Ajpendo.Zh1-5191-Corr.2007 |
0.322 |
|
| 2006 |
Bence KK, Delibegovic M, Xue B, Gorgun CZ, Hotamisligil GS, Neel BG, Kahn BB. Neuronal PTP1B regulates body weight, adiposity and leptin action. Nature Medicine. 12: 917-24. PMID 16845389 DOI: 10.1038/Nm1435 |
0.421 |
|
| 2006 |
Herman MA, Kahn BB. Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony. The Journal of Clinical Investigation. 116: 1767-75. PMID 16823474 DOI: 10.1172/Jci29027 |
0.471 |
|
| 2006 |
Graham TE, Yang Q, Blüher M, Hammarstedt A, Ciaraldi TP, Henry RR, Wason CJ, Oberbach A, Jansson PA, Smith U, Kahn BB. Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects. The New England Journal of Medicine. 354: 2552-63. PMID 16775236 DOI: 10.1056/Nejmoa054862 |
0.521 |
|
| 2006 |
Xue B, Kahn BB. AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues. The Journal of Physiology. 574: 73-83. PMID 16709629 DOI: 10.1113/Jphysiol.2006.113217 |
0.423 |
|
| 2006 |
Martin TL, Alquier T, Asakura K, Furukawa N, Preitner F, Kahn BB. Diet-induced obesity alters AMP kinase activity in hypothalamus and skeletal muscle. The Journal of Biological Chemistry. 281: 18933-41. PMID 16687413 DOI: 10.1074/Jbc.M512831200 |
0.394 |
|
| 2005 |
Kim YB, Peroni OD, Aschenbach WG, Minokoshi Y, Kotani K, Zisman A, Kahn CR, Goodyear LJ, Kahn BB. Muscle-specific deletion of the Glut4 glucose transporter alters multiple regulatory steps in glycogen metabolism. Molecular and Cellular Biology. 25: 9713-23. PMID 16227617 DOI: 10.1128/Mcb.25.21.9713-9723.2005 |
0.452 |
|
| 2005 |
Furukawa N, Ongusaha P, Jahng WJ, Araki K, Choi CS, Kim HJ, Lee YH, Kaibuchi K, Kahn BB, Masuzaki H, Kim JK, Lee SW, Kim YB. Role of Rho-kinase in regulation of insulin action and glucose homeostasis. Cell Metabolism. 2: 119-29. PMID 16098829 DOI: 10.1016/J.Cmet.2005.06.011 |
0.545 |
|
| 2005 |
Maeda K, Cao H, Kono K, Gorgun CZ, Furuhashi M, Uysal KT, Cao Q, Atsumi G, Malone H, Krishnan B, Minokoshi Y, Kahn BB, Parker RA, Hotamisligil GS. Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes. Cell Metabolism. 1: 107-19. PMID 16054052 DOI: 10.1016/J.Cmet.2004.12.008 |
0.506 |
|
| 2005 |
Kahn BB, Alquier T, Carling D, Hardie DG. AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. Cell Metabolism. 1: 15-25. PMID 16054041 DOI: 10.1016/J.Cmet.2004.12.003 |
0.489 |
|
| 2005 |
Yang Q, Graham TE, Mody N, Preitner F, Peroni OD, Zabolotny JM, Kotani K, Quadro L, Kahn BB. Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. Nature. 436: 356-62. PMID 16034410 DOI: 10.1038/Nature03711 |
0.563 |
|
| 2005 |
Carvalho E, Kotani K, Peroni OD, Kahn BB. Adipose-specific overexpression of GLUT4 reverses insulin resistance and diabetes in mice lacking GLUT4 selectively in muscle. American Journal of Physiology. Endocrinology and Metabolism. 289: E551-61. PMID 15928024 DOI: 10.1152/Ajpendo.00116.2005 |
0.558 |
|
| 2005 |
Jones JR, Barrick C, Kim KA, Lindner J, Blondeau B, Fujimoto Y, Shiota M, Kesterson RA, Kahn BB, Magnuson MA. Deletion of PPARgamma in adipose tissues of mice protects against high fat diet-induced obesity and insulin resistance. Proceedings of the National Academy of Sciences of the United States of America. 102: 6207-12. PMID 15833818 DOI: 10.1073/Pnas.0306743102 |
0.546 |
|
| 2005 |
Kurlawalla-Martinez C, Stiles B, Wang Y, Devaskar SU, Kahn BB, Wu H. Insulin hypersensitivity and resistance to streptozotocin-induced diabetes in mice lacking PTEN in adipose tissue. Molecular and Cellular Biology. 25: 2498-510. PMID 15743841 DOI: 10.1128/Mcb.25.6.2498-2510.2005 |
0.579 |
|
| 2005 |
Haj FG, Zabolotny JM, Kim YB, Kahn BB, Neel BG. Liver-specific protein-tyrosine phosphatase 1B (PTP1B) re-expression alters glucose homeostasis of PTP1B-/- mice Journal of Biological Chemistry. 280: 15038-15046. PMID 15699041 DOI: 10.1074/Jbc.M413240200 |
0.548 |
|
| 2005 |
Galic S, Hauser C, Kahn BB, Haj FG, Neel BG, Tonks NK, Tiganis T. Coordinated regulation of insulin signaling by the protein tyrosine phosphatases PTP1B and TCPTP Molecular and Cellular Biology. 25: 819-829. PMID 15632081 DOI: 10.1128/Mcb.25.2.819-829.2005 |
0.417 |
|
| 2005 |
Corbould A, Kim YB, Youngren JF, Pender C, Kahn BB, Lee A, Dunaif A. Insulin resistance in the skeletal muscle of women with PCOS involves intrinsic and acquired defects in insulin signaling. American Journal of Physiology. Endocrinology and Metabolism. 288: E1047-54. PMID 15613682 DOI: 10.1152/Ajpendo.00361.2004 |
0.514 |
|
| 2005 |
Chan JL, Moschos SJ, Bullen J, Heist K, Li X, Kim YB, Kahn BB, Mantzoros CS. Recombinant methionyl human leptin administration activates signal transducer and activator of transcription 3 signaling in peripheral blood mononuclear cells in vivo and regulates soluble tumor necrosis factor-alpha receptor levels in humans with relative leptin deficiency. The Journal of Clinical Endocrinology and Metabolism. 90: 1625-31. PMID 15613409 DOI: 10.1210/Jc.2004-1823 |
0.328 |
|
| 2004 |
Kotani K, Peroni OD, Minokoshi Y, Boss O, Kahn BB. GLUT4 glucose transporter deficiency increases hepatic lipid production and peripheral lipid utilization. The Journal of Clinical Investigation. 114: 1666-75. PMID 15578099 DOI: 10.1172/Jci21341 |
0.542 |
|
| 2004 |
Morroni M, Giordano A, Zingaretti MC, Boiani R, De Matteis R, Kahn BB, Nisoli E, Tonello C, Pisoschi C, Luchetti MM, Marelli M, Cinti S. Reversible transdifferentiation of secretory epithelial cells into adipocytes in the mammary gland. Proceedings of the National Academy of Sciences of the United States of America. 101: 16801-6. PMID 15556998 DOI: 10.1073/Pnas.0407647101 |
0.327 |
|
| 2004 |
Patti ME, Kahn BB. Nutrient sensor links obesity with diabetes risk. Nature Medicine. 10: 1049-50. PMID 15459705 DOI: 10.1038/Nm1004-1049 |
0.442 |
|
| 2004 |
Lamia KA, Peroni OD, Kim YB, Rameh LE, Kahn BB, Cantley LC. Increased insulin sensitivity and reduced adiposity in phosphatidylinositol 5-phosphate 4-kinase beta-/- mice. Molecular and Cellular Biology. 24: 5080-7. PMID 15143198 DOI: 10.1128/Mcb.24.11.5080-5087.2004 |
0.452 |
|
| 2004 |
Blüher M, Patti ME, Gesta S, Kahn BB, Kahn CR. Intrinsic heterogeneity in adipose tissue of fat-specific insulin receptor knock-out mice is associated with differences in patterns of gene expression. The Journal of Biological Chemistry. 279: 31891-901. PMID 15131119 DOI: 10.1074/Jbc.M404569200 |
0.463 |
|
| 2004 |
Minokoshi Y, Alquier T, Furukawa H, Kim YB, Lee A, Xue B, Mu J, Foufelle F, Ferré P, Birnbaum MJ, Stuck BJ, Kahn BB. AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus Nature. 428: 569-574. PMID 15058305 DOI: 10.1038/Nature02440 |
0.382 |
|
| 2004 |
Zabolotny JM, Haj FG, Kim YB, Kim HJ, Shulman GI, Kim JK, Neel BG, Kahn BB. Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not additively impair insulin action Journal of Biological Chemistry. 279: 24844-24851. PMID 15031294 DOI: 10.1074/Jbc.M310688200 |
0.541 |
|
| 2004 |
Carvalho E, Schellhorn SE, Zabolotny JM, Martin S, Tozzo E, Peroni OD, Houseknecht KL, Mundt A, James DE, Kahn BB. GLUT4 overexpression or deficiency in adipocytes of transgenic mice alters the composition of GLUT4 vesicles and the subcellular localization of GLUT4 and insulin-responsive aminopeptidase. The Journal of Biological Chemistry. 279: 21598-605. PMID 14985357 DOI: 10.1074/Jbc.M312269200 |
0.463 |
|
| 2004 |
Bjørbaek C, Kahn BB. Leptin signaling in the central nervous system and the periphery. Recent Progress in Hormone Research. 59: 305-31. PMID 14749508 DOI: 10.1210/Rp.59.1.305 |
0.396 |
|
| 2004 |
Kushner JA, Haj FG, Klaman LD, Dow MA, Kahn BB, Neel BG, White MF. Islet-sparing effects of protein tyrosine phosphatase-1b deficiency delays onset of diabetes in IRS2 knockout mice. Diabetes. 53: 61-6. PMID 14693698 DOI: 10.2337/Diabetes.53.1.61 |
0.523 |
|
| 2003 |
Kim YB, Kotani K, Ciaraldi TP, Henry RR, Kahn BB. Insulin-stimulated protein kinase C lambda/zeta activity is reduced in skeletal muscle of humans with obesity and type 2 diabetes: reversal with weight reduction. Diabetes. 52: 1935-42. PMID 12882908 DOI: 10.2337/Diabetes.52.8.1935 |
0.488 |
|
| 2003 |
Minokoshi Y, Kahn CR, Kahn BB. Tissue-specific ablation of the GLUT4 glucose transporter or the insulin receptor challenges assumptions about insulin action and glucose homeostasis. The Journal of Biological Chemistry. 278: 33609-12. PMID 12788932 DOI: 10.1074/Jbc.R300019200 |
0.518 |
|
| 2003 |
Burcelin R, Crivelli V, Perrin C, Da Costa A, Mu J, Kahn BB, Birnbaum MJ, Kahn CR, Vollenweider P, Thorens B. GLUT4, AMP kinase, but not the insulin receptor, are required for hepatoportal glucose sensor-stimulated muscle glucose utilization Journal of Clinical Investigation. 111: 1555-1562. PMID 12750405 DOI: 10.1172/Jci16888 |
0.495 |
|
| 2003 |
Blüher M, Kahn BB, Kahn CR. Extended longevity in mice lacking the insulin receptor in adipose tissue. Science (New York, N.Y.). 299: 572-4. PMID 12543978 DOI: 10.1126/Science.1078223 |
0.508 |
|
| 2002 |
Yamauchi T, Kamon J, Minokoshi Y, Ito Y, Waki H, Uchida S, Yamashita S, Noda M, Kita S, Ueki K, Eto K, Akanuma Y, Froguel P, Foufelle F, Ferre P, ... ... Kahn BB, et al. Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nature Medicine. 8: 1288-95. PMID 12368907 DOI: 10.1038/Nm788 |
0.447 |
|
| 2002 |
Choi CS, Kim YB, Lee FN, Zabolotny JM, Kahn BB, Youn JH. Lactate induces insulin resistance in skeletal muscle by suppressing glycolysis and impairing insulin signaling American Journal of Physiology - Endocrinology and Metabolism. 283. PMID 12110527 DOI: 10.1152/Ajpendo.00557.2001 |
0.539 |
|
| 2002 |
Blüher M, Michael MD, Peroni OD, Ueki K, Carter N, Kahn BB, Kahn CR. Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance. Developmental Cell. 3: 25-38. PMID 12110165 DOI: 10.1016/S1534-5807(02)00199-5 |
0.533 |
|
| 2002 |
Kim YB, Shulman GI, Kahn BB. Fatty acid infusion selectively impairs insulin action on Akt1 and protein kinase C Νζ but not on glycogen synthase kinase-3 Journal of Biological Chemistry. 277: 32915-32922. PMID 12095990 DOI: 10.1074/Jbc.M204710200 |
0.477 |
|
| 2002 |
Zabolotny JM, Bence-Hanulec KK, Stricker-Krongrad A, Haj F, Wang Y, Minokoshi Y, Kim YB, Elmquist JK, Tartaglia LA, Kahn BB, Neel BG. PTP1B regulates leptin signal transduction in vivo. Developmental Cell. 2: 489-95. PMID 11970898 DOI: 10.1016/S1534-5807(02)00148-X |
0.413 |
|
| 2002 |
Kim YB, Ciaraldi TP, Kong A, Kim D, Chu N, Mohideen P, Mudaliar S, Henry RR, Kahn BB. Troglitazone but not metformin restores insulin-stimulated phosphoinositide 3-kinase activity and increases p110beta protein levels in skeletal muscle of type 2 diabetic subjects. Diabetes. 51: 443-8. PMID 11812753 DOI: 10.2337/Diabetes.51.2.443 |
0.478 |
|
| 2002 |
Minokoshi Y, Kim YB, Peroni OD, Fryer LG, Müller C, Carling D, Kahn BB. Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase. Nature. 415: 339-43. PMID 11797013 DOI: 10.1038/415339A |
0.402 |
|
| 2002 |
Tanner CJ, Koves TR, Cortright RL, Pories WJ, Kim YB, Kahn BB, Dohm GL, Houmard JA. Effect of short-term exercise training on insulin-stimulated PI 3-kinase activity in middle-aged men. American Journal of Physiology. Endocrinology and Metabolism. 282: E147-53. PMID 11739095 DOI: 10.1152/Ajpendo.2002.282.1.E147 |
0.457 |
|
| 2001 |
Minokoshi Y, Kahn BB. Role of AMP-activated protein kinase in leptin-induced fatty acid oxidation in muscle Biochemical Society Transactions. 31: 196-201. PMID 12546684 DOI: 10.1042/Bst0310196 |
0.353 |
|
| 2001 |
Larkin LM, Reynolds TH, Supiano MA, Kahn BB, Halter JB. Effect of aging and obesity on insulin responsiveness and glut-4 glucose transporter content in skeletal muscle of Fischer 344 x Brown Norway rats. Journals of Gerontology Series a-Biological Sciences and Medical Sciences. 56. PMID 11682570 DOI: 10.1093/Gerona/56.11.B486 |
0.486 |
|
| 2001 |
Kim JK, Zisman A, Fillmore JJ, Peroni OD, Kotani K, Perret P, Zong H, Dong J, Kahn CR, Kahn BB, Shulman GI. Glucose toxicity and the development of diabetes in mice with muscle-specific inactivation of GLUT4. The Journal of Clinical Investigation. 108: 153-60. PMID 11435467 DOI: 10.1172/Jci10294 |
0.536 |
|
| 2001 |
Zabolotny JM, Kim YB, Peroni OD, Kim JK, Pani MA, Boss O, Klaman LD, Kamatkar S, Shulman GI, Kahn BB, Neel BG. Overexpression of the LAR (leukocyte antigen-related) protein-tyrosine phosphatase in muscle causes insulin resistance Proceedings of the National Academy of Sciences of the United States of America. 98: 5187-5192. PMID 11309481 DOI: 10.1073/Pnas.071050398 |
0.551 |
|
| 2001 |
Huppertz C, Fischer BM, Kim YB, Kotani K, Vidal-Puig A, Slieker LJ, Sloop KW, Lowell BB, Kahn BB. Uncoupling Protein 3 (UCP3) Stimulates Glucose Uptake in Muscle Cells through a Phosphoinositide 3-Kinase-dependent Mechanism Journal of Biological Chemistry. 276: 12520-12529. PMID 11278970 DOI: 10.1074/Jbc.M011708200 |
0.463 |
|
| 2001 |
Dickson LM, Lingohr MK, McCuaig J, Hügl SR, Snow L, Kahn BB, Myers MG, Rhodes CJ. Differential Activation of Protein Kinase B and p70S6K by Glucose and Insulin-like Growth Factor 1 in Pancreatic β-Cells (INS-1) Journal of Biological Chemistry. 276: 21110-21120. PMID 11274216 DOI: 10.1074/Jbc.M101257200 |
0.396 |
|
| 2001 |
Abel ED, Peroni O, Kim JK, Kim YB, Boss O, Hadro E, Minnemann T, Shulman GI, Kahn BB. Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver. Nature. 409: 729-33. PMID 11217863 DOI: 10.1038/35055575 |
0.568 |
|
| 2000 |
Kahn BB, Flier JS. Obesity and insulin resistance Journal of Clinical Investigation. 106: 473-481. PMID 10953022 DOI: 10.1172/Jci10842 |
0.464 |
|
| 2000 |
Zisman A, Peroni OD, Abel ED, Michael MD, Mauvais-Jarvis F, Lowell BB, Wojtaszewski JFP, Hirshman MF, Virkamaki A, Goodyear LJ, Kahn CR, Kahn BB. Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance Nature Medicine. 6: 924-928. PMID 10932232 DOI: 10.1038/78693 |
0.506 |
|
| 2000 |
Rasmussen SK, Hansen L, Frevert EU, Cohen PTW, Kahn BB, Pedersen O. Adenovirus-mediated expression of a naturally occurring Asp905Tyr variant of the glycogen-associated regulatory subunit of protein phosphatase- 1 in L6 myotubes Diabetologia. 43: 718-722. PMID 10907117 DOI: 10.1007/S001250051369 |
0.501 |
|
| 2000 |
Kim YB, Peroni OD, Franke TF, Kahn BB. Divergent regulation of Akt1 and Akt2 isoforms in insulin target tissues of obese Zucker rats. Diabetes. 49: 847-856. PMID 10905496 DOI: 10.2337/Diabetes.49.5.847 |
0.522 |
|
| 2000 |
Klaman LD, Boss O, Peroni OD, Kim JK, Martino JL, Zabolotny JM, Moghal N, Lubkin M, Kim YB, Sharpe AH, Stricker-Krongrad A, Shulman GI, Neel BG, Kahn BB. Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice Molecular and Cellular Biology. 20: 5479-5489. PMID 10891488 DOI: 10.1128/Mcb.20.15.5479-5489.2000 |
0.521 |
|
| 2000 |
Kim Y, Uotani S, Pierroz DD, Flier JS, Kahn BB. In vivo administration of leptin activates signal transduction directly in insulin-sensitive tissues: overlapping but distinct pathways from insulin. Endocrinology. 141: 2328-2339. PMID 10875232 DOI: 10.1210/Endo.141.7.7536 |
0.494 |
|
| 2000 |
Permana PA, Kahn BB, Huppertz C, Mott DM. Functional analyses of amino acid substitutions Arg883Ser and Asp905Tyr of protein phosphatase-1 G-subunit. Molecular Genetics and Metabolism. 70: 151-8. PMID 10873397 DOI: 10.1006/Mgme.2000.3011 |
0.461 |
|
| 2000 |
Kim JK, Michael MD, Previs SF, Peroni OD, Mauvais-Jarvis F, Neschen S, Kahn BB, Kahn CR, Shulman GI. Redistribution of substrates to adipose tissue promotes obesity in mice with selective insulin resistance in muscle Journal of Clinical Investigation. 105: 1791-1797. PMID 10862794 DOI: 10.1172/Jci8305 |
0.557 |
|
| 2000 |
Venable CL, Frevert EU, Kim YB, Fischer BM, Kamatkar S, Neel BG, Kahn BB. Overexpression of protein-tyrosine phosphatase-1B in adipocytes inhibits insulin-stimulated phosphoinositide 3-kinase activity without altering glucose transport or Akt/protein kinase B activation Journal of Biological Chemistry. 275: 18318-18326. PMID 10751417 DOI: 10.1074/Jbc.M908392199 |
0.54 |
|
| 2000 |
Xie Z, Li H, Liu L, Kahn BB, Najjar SM, Shah W. Metabolic regulation of Na(+)/P(i)-cotransporter-1 gene expression in H4IIE cells. American Journal of Physiology. Endocrinology and Metabolism. 278: E648-55. PMID 10751198 DOI: 10.1152/Ajpendo.2000.278.4.E648 |
0.489 |
|
| 1999 |
Abel ED, Kaulbach HC, Tian R, Hopkins JC, Duffy J, Doetschman T, Minnemann T, Boers ME, Hadro E, Oberste-Berghaus C, Quist W, Lowell BB, Ingwall JS, Kahn BB. Cardiac hypertrophy with preserved contractile function after selective deletion of GLUT4 from the heart. The Journal of Clinical Investigation. 104: 1703-14. PMID 10606624 DOI: 10.1172/Jci7605 |
0.45 |
|
| 1999 |
Kim Y, Nikoulina SE, Ciaraldi TP, Henry RR, Kahn BB. Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes Journal of Clinical Investigation. 104: 733-741. PMID 10491408 DOI: 10.1172/Jci6928 |
0.485 |
|
| 1999 |
Shepherd PR, Kahn BB. Glucose transporters and insulin action--implications for insulin resistance and diabetes mellitus. The New England Journal of Medicine. 341: 248-257. PMID 10413738 DOI: 10.1056/Nejm199907223410406 |
0.525 |
|
| 1999 |
Kim YB, Zhu JS, Zierath JR, Shen HQ, Baron AD, Kahn BB. Glucosamine infusion in rats rapidly impairs insulin stimulation of phosphoinositide 3-kinase but does not alter activation of Akt/protein kinase B in skeletal muscle. Diabetes. 48: 310-20. PMID 10334307 DOI: 10.2337/Diabetes.48.2.310 |
0.494 |
|
| 1998 |
Kahn BB, Rossetti L. Type 2 diabetes--who is conducting the orchestra? Nature Genetics. 20: 223-5. PMID 9806535 DOI: 10.1038/3018 |
0.532 |
|
| 1998 |
Frevert EU, Bjørbaek C, Venable CL, Keller SR, Kahn BB. Targeting of constitutively active phosphoinositide 3-kinase to GLUT4-containing vesicles in 3T3-L1 adipocytes. The Journal of Biological Chemistry. 273: 25480-7. PMID 9738018 DOI: 10.1074/Jbc.273.39.25480 |
0.448 |
|
| 1998 |
Goodyear LJ, Kahn BB. Exercise, glucose transport, and insulin sensitivity. Annual Review of Medicine. 49: 235-261. PMID 9509261 DOI: 10.1146/Annurev.Med.49.1.235 |
0.453 |
|
| 1998 |
Kahn BB. Type 2 diabetes: when insulin secretion fails to compensate for insulin resistance. Cell. 92: 593-596. PMID 9506512 DOI: 10.1016/S0092-8674(00)81125-3 |
0.472 |
|
| 1998 |
Sutherland C, Waltner-Law M, Gnudi L, Kahn BB, Granner DK. Activation of the Ras mitogen-activated protein kinase-ribosomal protein kinase pathway is not required for the repression of phosphoenolpyruvate carboxykinase gene transcription by insulin Journal of Biological Chemistry. 273: 3198-3204. PMID 9452431 DOI: 10.1074/Jbc.273.6.3198 |
0.395 |
|
| 1998 |
Zierath JR, Frevert EU, Ryder JW, Berggren PO, Kahn BB. Evidence against a direct effect of leptin on glucose transport in skeletal muscle and adipocytes Diabetes. 47: 1-4. PMID 9421367 DOI: 10.2337/Diab.47.1.1 |
0.487 |
|
| 1997 |
Tozzo E, Gnudi L, Kahn BB. Amelioration Of Insulin Resistance In Streptozotocin Diabetic Mice By Transgenic Overexpression Of Glut4 Driven By An Adipose-Specific Promoter Endocrinology. 138: 1604-1611. PMID 9075721 DOI: 10.1210/Endo.138.4.5043 |
0.53 |
|
| 1997 |
Zierath JR, Houseknecht KL, Gnudi L, Kahn BB. High-Fat Feeding Impairs Insulin-Stimulated GLUT4 Recruitment via an Early Insulin-Signaling Defect Diabetes. 46: 215-223. PMID 9000697 DOI: 10.2337/Diab.46.2.215 |
0.526 |
|
| 1997 |
Gnudi L, Frevert EU, Houseknecht KL, Erhardt P, Kahn BB. Adenovirus-mediated gene transfer of dominant negative Ras(asn17) in 3T3L1 adipocytes does not alter insulin-stimulated PI3-kinase activity or glucose transport Molecular Endocrinology. 11: 67-76. PMID 8994189 DOI: 10.1210/Mend.11.1.9866 |
0.437 |
|
| 1997 |
Frevert EU, Kahn BB. Differential Effects of Constitutively Active Phosphatidylinositol 3-Kinase on Glucose Transport, Glycogen Synthase Activity, and DNA Synthesis in 3T3-L1 Adipocytes Molecular and Cellular Biology. 17: 190-198. PMID 8972199 DOI: 10.1128/Mcb.17.1.190 |
0.497 |
|
| 1997 |
Houseknecht KL, Kahn BB. Molecular Mechanisms for Insulin-Stimulated Glucose Transport: Regulation of Glut4 Translocation Journal of Animal Science. 75: 32-45. DOI: 10.2527/Animalsci1997.75Supplement_232X |
0.477 |
|
| 1996 |
Gnudi L, Jensen DR, Tozzo E, Eckel RH, Kahn BB. Adipose-specific overexpression of GLUT-4 in transgenic mice alters lipoprotein lipase activity American Journal of Physiology-Regulatory Integrative and Comparative Physiology. 270: 785. PMID 8967408 DOI: 10.1152/Ajpregu.1996.270.4.R785 |
0.531 |
|
| 1996 |
Magnan C, Gilbert M, Kahn BB. Chronic free fatty acid infusion in rats results in insulin resistance but no alteration in insulin-responsive glucose transporter levels in skeletal muscle. Lipids. 31: 1141-1149. PMID 8934446 DOI: 10.1007/Bf02524288 |
0.502 |
|
| 1996 |
Kahn BB. Lilly lecture 1995. Glucose transport: pivotal step in insulin action. Diabetes. 45: 1644-1654. PMID 8866574 DOI: 10.2337/Diab.45.11.1644 |
0.557 |
|
| 1996 |
Houseknecht KL, Mantzoros CS, Kuliawat R, Hadro E, Flier JS, Kahn BB. Evidence for Leptin Binding to Proteins in Serum of Rodents and Humans: Modulation With Obesity Diabetes. 45: 1638-1643. PMID 8866573 DOI: 10.2337/Diab.45.11.1638 |
0.337 |
|
| 1996 |
Gnudi L, Shepherd PR, Kahn BB. Over-expression of GLUT4 selectively in adipose tissue in transgenic mice: implications for nutrient partitioning. The Proceedings of the Nutrition Society. 55: 191-9. PMID 8832791 DOI: 10.1079/PNS19960020 |
0.439 |
|
| 1996 |
Frevert EU, Kahn BB. Protein kinase C isoforms epsilon, eta, delta and zeta in murine adipocytes: expression, subcellular localization and tissue-specific regulation in insulin-resistant states. Biochemical Journal. 316: 865-871. PMID 8670164 DOI: 10.1042/Bj3160865 |
0.504 |
|
| 1996 |
Tozzo E, Kahn BB, Pilch PF, Kandror KV. Glut4 is targeted to specific vesicles in adipocytes of transgenic mice overexpressing Glut4 selectively in adipose tissue Journal of Biological Chemistry. 271: 10490-10494. PMID 8631845 DOI: 10.1074/Jbc.271.18.10490 |
0.422 |
|
| 1996 |
Houseknecht KL, Zhu AX, Gnudi L, Hamann A, Zierath JR, Tozzo E, Flier JS, Kahn BB. Overexpression of Ha-ras Selectively in Adipose Tissue of Transgenic Mice EVIDENCE FOR ENHANCED SENSITIVITY TO INSULIN Journal of Biological Chemistry. 271: 11347-11355. PMID 8626688 DOI: 10.1074/Jbc.271.19.11347 |
0.518 |
|
| 1996 |
Gabbay RA, Sutherland C, Gnudi L, Kahn BB, O'Brien RM, Granner DK, Flier JS. Insulin Regulation of Phosphoenolpyruvate Carboxykinase Gene Expression Does Not Require Activation of the Ras/Mitogen-activated Protein Kinase Signaling Pathway Journal of Biological Chemistry. 271: 1890-1897. PMID 8567635 DOI: 10.1074/Jbc.271.4.1890 |
0.442 |
|
| 1996 |
Kahn BB. Lilly lecture 1995. Glucose transport: pivotal step in insulin action Diabetes. 45: 1644-1654. DOI: 10.2337/diabetes.45.11.1644 |
0.392 |
|
| 1996 |
Zierath JR, Houseknecht KL, Kahn BB. Glucose transporters and diabetes Seminars in Cell & Developmental Biology. 7: 295-307. DOI: 10.1006/Scdb.1996.0038 |
0.543 |
|
| 1995 |
Gnudi L, Tozzo E, Shepherd PR, Bliss JL, Kahn BB. High level overexpression of glucose transporter-4 driven by an adipose-specific promoter is maintained in transgenic mice on a high fat diet, but does not prevent impaired glucose tolerance. Endocrinology. 136: 995-1002. PMID 7867610 DOI: 10.1210/Endo.136.3.7867610 |
0.532 |
|
| 1995 |
Vestergaard H, Weinreb JE, Rosen AS, Bjørbaek C, Hansen L, Pedersen O, Kahn BB. Sulfonylurea therapy improves glucose disposal without changing skeletal muscle GLUT4 levels in noninsulin-dependent diabetes mellitus subjects: a longitudinal study. The Journal of Clinical Endocrinology and Metabolism. 80: 270-275. PMID 7829624 DOI: 10.1210/Jcem.80.1.7829624 |
0.498 |
|
| 1995 |
Tozzo E, Shepherd PR, Gnudi L, Kahn BB. Transgenic GLUT-4 overexpression in fat enhances glucose metabolism: preferential effect on fatty acid synthesis American Journal of Physiology-Endocrinology and Metabolism. 268. PMID 7762651 DOI: 10.1152/Ajpendo.1995.268.5.E956 |
0.461 |
|
| 1995 |
Frederich RC, Löllmann B, Hamann A, Napolitano-Rosen A, Kahn BB, Lowell BB, Flier JS. Expression of ob mRNA and its encoded protein in rodents. Impact of nutrition and obesity. The Journal of Clinical Investigation. 96: 1658-63. PMID 7657836 DOI: 10.1172/Jci118206 |
0.361 |
|
| 1995 |
Zierath JR, Nolte LA, Wahlström E, Galuska D, Shepherd PR, Kahn BB, Wallberg-Henriksson H. Carrier-mediated fructose uptake significantly contributes to carbohydrate metabolism in human skeletal muscle. Biochemical Journal. 311: 517-521. PMID 7487889 DOI: 10.1042/Bj3110517 |
0.458 |
|
| 1995 |
Abel ED, Houseknecht KL, Kahn BB. Recent advances in understanding the molecular basis for insulin-stimulated glucose transport Current Opinion in Endocrinology & Diabetes. 2: 313-324. DOI: 10.1097/00060793-199508000-00006 |
0.47 |
|
| 1994 |
Rajan AS, Luo ZT, Kahn BB, Comstock JP, Cushman SW, Boyd AE. Do adipocytes contain high affinity sulfonylurea receptors. Endocrinology. 134: 1581-8. PMID 8119201 DOI: 10.1210/Endo.134.3.8119201 |
0.4 |
|
| 1994 |
Kahn BB. Dietary regulation of glucose transporter gene expression: tissue specific effects in adipose cells and muscle. Journal of Nutrition. 124. PMID 8064377 DOI: 10.1093/Jn/124.Suppl_8.1289S |
0.453 |
|
| 1994 |
Moran A, Pyzdrowski KL, Weinreb J, Kahn BB, Smith SA, Adams KS, Seaquist ER. Insulin sensitivity in cystic fibrosis Diabetes. 43: 1020-1026. PMID 8039595 DOI: 10.2337/Diab.43.8.1020 |
0.536 |
|
| 1993 |
Kahn BB, Pedersen O. Suppression of GLUT4 expression in skeletal muscle of rats that are obese from high fat feeding but not from high carbohydrate feeding or genetic obesity Endocrinology. 132: 13-22. PMID 8419118 DOI: 10.1210/Endo.132.1.8419118 |
0.425 |
|
| 1993 |
Elahi D, McAloon-Dyke M, Clark BA, Kahn BB, Weinreb JE, Minaker KL, Wong GA, Morse LA, Brown RS, Shapiro ME. Sequential evaluation of islet cell responses to glucose in the transplanted pancreas in humans. American Journal of Surgery. 165: 15-22. PMID 8418690 DOI: 10.1016/S0002-9610(05)80398-8 |
0.453 |
|
| 1993 |
Flier JS, Moller DE, Moses AC, O'Rahilly S, Chaiken RL, Grigorescu F, Elahi D, Kahn BB, Weinreb JE, Eastman R. Insulin-mediated pseudoacromegaly: clinical and biochemical characterization of a syndrome of selective insulin resistance. The Journal of Clinical Endocrinology and Metabolism. 76: 1533-41. PMID 8388881 DOI: 10.1210/Jcem.76.6.8388881 |
0.491 |
|
| 1993 |
Hughes VA, Fiatarone MA, Fielding RA, Kahn BB, Ferrara CM, Shepherd P, Fisher EC, Wolfe RR, Elahi D, Evans WJ. Exercise increases muscle GLUT-4 levels and insulin action in subjects with impaired glucose tolerance. The American Journal of Physiology. 264: E855-62. PMID 8333511 DOI: 10.1152/Ajpendo.1993.264.6.E855 |
0.483 |
|
| 1993 |
Andersen PH, Lund S, Vestergaard H, Junker S, Kahn BB, Pedersen O. Expression of the major insulin regulatable glucose transporter (GLUT4) in skeletal muscle of noninsulin-dependent diabetic patients and healthy subjects before and after insulin infusion. The Journal of Clinical Endocrinology and Metabolism. 77: 27-32. PMID 8325952 DOI: 10.1210/Jcem.77.1.8325952 |
0.494 |
|
| 1993 |
Andersen PH, Lund S, Schmitz O, Junker S, Kahn BB, Pedersen O. Increased insulin-stimulated glucose uptake in athletes : the importance of GLUT4 mRNA, GLUT4 protein and fibre type composition of skeletal muscle Acta Physiologica Scandinavica. 149: 393-404. PMID 8128887 DOI: 10.1111/J.1748-1716.1993.Tb09635.X |
0.446 |
|
| 1993 |
Andersen PH, Vestergaard H, Lund S, Vedel P, Junker S, Kahn BB, Pedersen O. The Effect of Intensive Insulin Therapy on the Insulin-regulatable Glucose Transporter (GLUT4) Expression in Skeletal Muscle in Type 1 Diabetes. Diabetic Medicine. 10: 699-706. PMID 7505214 DOI: 10.1111/J.1464-5491.1993.Tb00151.X |
0.524 |
|
| 1993 |
Shepherd P, Gnudi L, Tozzo E, Yang H, Leach F, Kahn B. Adipose cell hyperplasia and enhanced glucose disposal in transgenic mice overexpressing GLUT4 selectively in adipose tissue. Journal of Biological Chemistry. 268: 22243-22246. DOI: 10.1016/s0021-9258(18)41516-5 |
0.367 |
|
| 1992 |
Alexander-Bridges M, Buggs C, Giere L, Denaro M, Kahn B, White M, Sukhatme V, Nasrin N. Models of insulin action on metabolic and growth response genes. Molecular and Cellular Biochemistry. 109: 99-105. PMID 1625685 DOI: 10.1007/Bf00229762 |
0.497 |
|
| 1992 |
Kahn BB. Alterations in glucose transporter expression and function in diabetes: mechanisms for insulin resistance. Journal of Cellular Biochemistry. 48: 122-128. PMID 1618926 DOI: 10.1002/Jcb.240480203 |
0.53 |
|
| 1992 |
Kahn BB, Pedersen O. Tissue-specific regulation of glucose transporters in different forms of obesity. Experimental Biology and Medicine. 200: 214-217. PMID 1579586 DOI: 10.3181/00379727-200-43421 |
0.543 |
|
| 1992 |
Kahn BB. Facilitative glucose transporters: regulatory mechanisms and dysregulation in diabetes. Journal of Clinical Investigation. 89: 1367-1374. PMID 1569179 DOI: 10.1172/Jci115724 |
0.389 |
|
| 1992 |
Kahn BB, Rosen AS, Bak JF, Andersen PH, Damsbo P, Lund S, Pedersen O. Expression of GLUT1 and GLUT4 glucose transporters in skeletal muscle of humans with insulin-dependent diabetes mellitus: regulatory effects of metabolic factors. The Journal of Clinical Endocrinology and Metabolism. 74: 1101-1109. PMID 1569156 DOI: 10.1210/Jcem.74.5.1569156 |
0.539 |
|
| 1992 |
Frederich RC, Kahn BB, Peach MJ, Flier JS. Tissue-specific nutritional regulation of angiotensinogen in adipose tissue. Hypertension. 19: 339-344. PMID 1555865 DOI: 10.1161/01.Hyp.19.4.339 |
0.314 |
|
| 1992 |
Pedersen O, Kahn CR, Kahn BB. Divergent regulation of the Glut 1 and Glut 4 glucose transporters in isolated adipocytes from Zucker rats. Journal of Clinical Investigation. 89: 1964-1973. PMID 1534819 DOI: 10.1172/Jci115804 |
0.446 |
|
| 1992 |
Gould GW, Brant AM, Kahn BB, Shepherd PR, McCoid SC, Gibbs EM. Expression of the brain-type glucose transporter is restricted to brain and neuronal cells in mice. Diabetologia. 35: 304-9. PMID 1516757 DOI: 10.1007/Bf00401196 |
0.442 |
|
| 1992 |
Shepherd PR, Gould GW, Colville CA, McCoid SC, Gibbs EM, Kahn BB. Distribution of GLUT3 glucose transporter protein in human tissues. Biochemical and Biophysical Research Communications. 188: 149-54. PMID 1417839 DOI: 10.1016/0006-291X(92)92362-2 |
0.376 |
|
| 1992 |
Shepherd PR, Gibbs EM, Wesslau C, Gould GW, Kahn BB. Human small intestine facilitative fructose/glucose transporter (GLUT5) is also present in insulin-responsive tissues and brain. Investigation of biochemical characteristics and translocation. Diabetes. 41: 1360-5. PMID 1397712 DOI: 10.2337/Diab.41.10.1360 |
0.491 |
|
| 1992 |
Hanks J, McAloon-Dyke M, Clark B, Kahn B, Weinreb J, Minaker K, Wong G, Morse L, Brown R, Shapiro M, Gingerich R, Rosenlof L, Pruett T, Andersen D, Elahi D. Insulin response, glucose homeostasis and glut4 levels in muscle after pancreas transplant: Comparison of initial study with one year follow-up Regulatory Peptides. 40: 166. DOI: 10.1016/0167-0115(92)90250-X |
0.453 |
|
| 1991 |
Kahn BB, Rossetti L, Lodish HF, Charron MJ. Decreased in vivo glucose uptake but normal expression of GLUT1 and GLUT4 in skeletal muscle of diabetic rats Journal of Clinical Investigation. 87: 2197-2206. PMID 2040701 DOI: 10.1172/Jci115254 |
0.479 |
|
| 1991 |
Kahn BB, Shulman GI, DeFronzo RA, Cushman SW, Rossetti L. Normalization of blood glucose in diabetic rats with phlorizin treatment reverses insulin-resistant glucose transport in adipose cells without restoring glucose transporter gene expression. The Journal of Clinical Investigation. 87: 561-70. PMID 1991839 DOI: 10.1172/Jci115031 |
0.538 |
|
| 1991 |
Tal M, Kahn BB, Lodish HF. Expression of the low Km GLUT-1 glucose transporter is turned on in perivenous hepatocytes of insulin-deficient diabetic rats. Endocrinology. 129: 1933-41. PMID 1915077 DOI: 10.1210/Endo-129-4-1933 |
0.484 |
|
| 1991 |
Pedersen O, Kahn CR, Flier JS, Kahn BB. High fat feeding causes insulin resistance and a marked decrease in the expression of glucose transporters (Glut 4) in fat cells of rats. Endocrinology. 129: 771-777. PMID 1855475 DOI: 10.1210/Endo-129-2-771 |
0.469 |
|
| 1990 |
Pedersen O, Bak JF, Andersen PH, Lund S, Moller DE, Flier JS, Kahn BB. Evidence Against Altered Expression of GLUT1 or GLUT4 in Skeletal Muscle of Patients With Obesity or NIDDM Diabetes. 39: 865-870. PMID 2354749 DOI: 10.2337/Diab.39.7.865 |
0.519 |
|
| 1990 |
Kahn BB, Flier JS. Regulation of Glucose-Transporter Gene Expression In Vitro and In Vivo Diabetes Care. 13: 548-564. PMID 2192844 DOI: 10.2337/Diacare.13.6.548 |
0.464 |
|
| 1990 |
Ploug T, Stallknecht BM, Pedersen O, Kahn BB, Ohkuwa T, Vinten J, Galbo H. Effect of endurance training on glucose transport capacity and glucose transporter expression in rat skeletal muscle American Journal of Physiology-Endocrinology and Metabolism. 259. PMID 2175551 DOI: 10.1152/Ajpendo.1990.259.6.E778 |
0.374 |
|
| 1990 |
Thorens B, Flier JS, Lodish HF, Kahn BB. Differential regulation of two glucose transporters in rat liver by fasting and refeeding and by diabetes and insulin treatment. Diabetes. 39: 712-9. PMID 2140804 DOI: 10.2337/Diab.39.6.712 |
0.41 |
|
| 1990 |
Charron MJ, Kahn BB. Divergent molecular mechanisms for insulin-resistant glucose transport in muscle and adipose cells in vivo. Journal of Biological Chemistry. 265: 7994-8000. DOI: 10.1016/s0021-9258(19)39029-5 |
0.401 |
|
| 1989 |
Kahn BB, Cushman SW, Flier JS. Regulation of glucose transporter-specific mRNA levels in rat adipose cells with fasting and refeeding. Implications for in vivo control of glucose transporter number. The Journal of Clinical Investigation. 83: 199-204. PMID 2910908 DOI: 10.1172/Jci113859 |
0.443 |
|
| 1989 |
Kahn BB, Charron MJ, Lodish HF, Cushman SW, Flier JS. Differential regulation of two glucose transporters in adipose cells from diabetic and insulin-treated diabetic rats. The Journal of Clinical Investigation. 84: 404-11. PMID 2668332 DOI: 10.1172/Jci114180 |
0.503 |
|
| 1988 |
Kahn BB, Simpson IA, Cushman SW. Divergent mechanisms for the insulin resistant and hyperresponsive glucose transport in adipose cells from fasted and refed rats. Alterations in both glucose transporter number and intrinsic activity Journal of Clinical Investigation. 82: 691-699. PMID 3403723 DOI: 10.1172/Jci113649 |
0.454 |
|
| 1987 |
Kahn BB, Horton ES, Cushman SW. Mechanism for enhanced glucose transport response to insulin in adipose cells from chronically hyperinsulinemic rats. Increased translocation of glucose transporters from an enlarged intracellular pool Journal of Clinical Investigation. 79: 853-858. PMID 3029179 DOI: 10.1172/Jci112894 |
0.494 |
|
| 1987 |
Kahn B, Cushman S. Mechanism for markedly hyperresponsive insulin-stimulated glucose transport activity in adipose cells from insulin-treated streptozotocin diabetic rats. Evidence for increased glucose transporter intrinsic activity. Journal of Biological Chemistry. 262: 5118-5124. DOI: 10.1016/s0021-9258(18)61162-7 |
0.426 |
|
| 1986 |
Kahn BB, Cushman SW. Cell Biology of Insulin's Stimulatory Action on Glucose Transport and Its Perturbation in Altered Metabolic States Annals of the New York Academy of Sciences. 488: 356-369. DOI: 10.1111/J.1749-6632.1986.Tb54417.X |
0.48 |
|
| 1985 |
Kahn BB, Cushman SW. Subcellular translocation of glucose transporters: Role in insulin action and its perturbation in altered metabolic states Diabetes/Metabolism Reviews. 1: 203-227. PMID 3915254 DOI: 10.1002/Dmr.5610010301 |
0.5 |
|
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