Year |
Citation |
Score |
2019 |
Wang W, Rodriguez-Silva M, Acanda de la Rocha AM, Wolf AL, Lai Y, Liu Y, Reinhold WC, Pommier Y, Chambers JW, Tse-Dinh YC. Tyrosyl-DNA Phosphodiesterase 1 and Topoisomerase I Activities as Predictive Indicators for Glioblastoma Susceptibility to Genotoxic Agents. Cancers. 11. PMID 31547492 DOI: 10.3390/Cancers11101416 |
0.333 |
|
2019 |
Lucero M, Suarez AE, Chambers JW. Phosphoregulation on mitochondria: Integration of cell and organelle responses. Cns Neuroscience & Therapeutics. PMID 31025544 DOI: 10.1111/Cns.13141 |
0.33 |
|
2018 |
Paudel I, Hernandez SM, Portalatin GM, Chambers TP, Chambers JW. Sab Concentrations Indicate Chemotherapeutic Susceptibility in Ovarian Cancer Cell Lines. The Biochemical Journal. PMID 30322886 DOI: 10.1042/Bcj20180603 |
0.351 |
|
2017 |
Chambers TP, Santiesteban L, Gomez D, Chambers JW. Sab mediates mitochondrial dysfunction involved in imatinib mesylate-induced cardiotoxicity. Toxicology. PMID 28315715 DOI: 10.1016/J.Tox.2017.03.006 |
0.367 |
|
2015 |
Chambers TP, Portalatin GM, Paudel I, Robbins CJ, Chambers JW. Sub-chronic administration of LY294002 sensitizes cervical cancer cells to chemotherapy by enhancing mitochondrial JNK signaling. Biochemical and Biophysical Research Communications. 463: 538-44. PMID 26032505 DOI: 10.1016/J.Bbrc.2015.05.075 |
0.34 |
|
2015 |
Alonso N, Guillen R, Chambers JW, Leng F. A rapid and sensitive high-throughput screening method to identify compounds targeting protein-nucleic acids interactions. Nucleic Acids Research. 43: e52. PMID 25653160 DOI: 10.1093/Nar/Gkv069 |
0.318 |
|
2015 |
Prado A, Petroianu GA, Lorke DE, Chambers JW. A trivalent approach for determining in vitro toxicology: Examination of oxime K027. Journal of Applied Toxicology : Jat. 35: 219-27. PMID 24853289 DOI: 10.1002/Jat.3013 |
0.339 |
|
2015 |
Silva MR, Aberman Z, Portalatin G, Chambers T, Gonzalez-Arias S, Chambers J. CSIG-01Sab-MEDIATED SIGNALING INFLUENCES AEROBIC GLYCOLYSIS AND CHEMOSUSCEPTIBILITY IN HUMAN NEUROBLASTOMA CELLS Neuro-Oncology. 17: v66.1-v66. DOI: 10.1093/Neuonc/Nov210.01 |
0.363 |
|
2013 |
Feng Y, Chambers JW, Iqbal S, Koenig M, Park H, Cherry L, Hernandez P, Figuera-Losada M, LoGrasso PV. A small molecule bidentate-binding dual inhibitor probe of the LRRK2 and JNK kinases. Acs Chemical Biology. 8: 1747-54. PMID 23751758 DOI: 10.1021/Cb3006165 |
0.394 |
|
2013 |
Chambers JW, Pachori A, Howard S, Iqbal S, LoGrasso PV. Inhibition of JNK mitochondrial localization and signaling is protective against ischemia/reperfusion injury in rats. The Journal of Biological Chemistry. 288: 4000-11. PMID 23258542 DOI: 10.1074/Jbc.M112.406777 |
0.326 |
|
2013 |
Chambers JW, Howard S, LoGrasso PV. Blocking c-Jun N-terminal kinase (JNK) translocation to the mitochondria prevents 6-hydroxydopamine-induced toxicity in vitro and in vivo. The Journal of Biological Chemistry. 288: 1079-87. PMID 23184940 DOI: 10.1074/Jbc.M112.421354 |
0.349 |
|
2011 |
Chambers JW, Pachori A, Howard S, Ganno M, Hansen D, Kamenecka T, Song X, Duckett D, Chen W, Ling YY, Cherry L, Cameron MD, Lin L, Ruiz CH, Lograsso P. Small Molecule c-jun-N-terminal Kinase (JNK) Inhibitors Protect Dopaminergic Neurons in a Model of Parkinson's Disease. Acs Chemical Neuroscience. 2: 198-206. PMID 21666839 DOI: 10.1021/Cn100109K |
0.323 |
|
2011 |
Chambers JW, Cherry L, Laughlin JD, Figuera-Losada M, Lograsso PV. Selective inhibition of mitochondrial JNK signaling achieved using peptide mimicry of the Sab kinase interacting motif-1 (KIM1). Acs Chemical Biology. 6: 808-18. PMID 21563797 DOI: 10.1021/Cb200062A |
0.346 |
|
2011 |
Chambers JW, LoGrasso PV. Mitochondrial c-Jun N-terminal kinase (JNK) signaling initiates physiological changes resulting in amplification of reactive oxygen species generation. The Journal of Biological Chemistry. 286: 16052-62. PMID 21454558 DOI: 10.1074/Jbc.M111.223602 |
0.346 |
|
2011 |
Dodson HC, Lyda TA, Chambers JW, Morris MT, Christensen KA, Morris JC. Quercetin, a fluorescent bioflavanoid, inhibits Trypanosoma brucei hexokinase 1. Experimental Parasitology. 127: 423-8. PMID 20971104 DOI: 10.1016/J.Exppara.2010.10.011 |
0.512 |
|
2010 |
Kamenecka T, Jiang R, Song X, Duckett D, Chen W, Ling YY, Habel J, Laughlin JD, Chambers J, Figuera-Losada M, Cameron MD, Lin L, Ruiz CH, LoGrasso PV. Synthesis, biological evaluation, X-ray structure, and pharmacokinetics of aminopyrimidine c-jun-N-terminal kinase (JNK) inhibitors. Journal of Medicinal Chemistry. 53: 419-31. PMID 19947601 DOI: 10.1021/Jm901351F |
0.376 |
|
2010 |
Chambers JW, Maguire TG, Alwine JC. Glutamine metabolism is essential for human cytomegalovirus infection. Journal of Virology. 84: 1867-73. PMID 19939921 DOI: 10.1128/Jvi.02123-09 |
0.325 |
|
2008 |
Chambers JW, Kearns MT, Morris MT, Morris JC. Assembly of heterohexameric trypanosome hexokinases reveals that hexokinase 2 is a regulable enzyme. The Journal of Biological Chemistry. 283: 14963-70. PMID 18387941 DOI: 10.1074/Jbc.M802124200 |
0.578 |
|
2008 |
Chambers JW, Fowler ML, Morris MT, Morris JC. The anti-trypanosomal agent lonidamine inhibits Trypanosoma brucei hexokinase 1. Molecular and Biochemical Parasitology. 158: 202-7. PMID 18262292 DOI: 10.1016/J.Molbiopara.2007.12.013 |
0.614 |
|
2008 |
Chambers JW, Morris MT, Smith KS, Morris JC. Residues in an ATP binding domain influence sugar binding in a trypanosome hexokinase. Biochemical and Biophysical Research Communications. 365: 420-5. PMID 17996732 DOI: 10.1016/J.Bbrc.2007.10.192 |
0.535 |
|
2006 |
Morris MT, DeBruin C, Yang Z, Chambers JW, Smith KS, Morris JC. Activity of a second Trypanosoma brucei hexokinase is controlled by an 18-amino-acid C-terminal tail. Eukaryotic Cell. 5: 2014-23. PMID 17028241 DOI: 10.1128/Ec.00146-06 |
0.577 |
|
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