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Eric M. Phizicky - Publications

Affiliations: 
Biochemistry and Biophysics University of Rochester Medical Center, Rochester, NY, United States 
Area:
tRNA Biogenesis, Function and Quality Control
Website:
http://www.urmc.rochester.edu/people/20653606-eric-m-phizicky
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93 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Funk HM, DiVita DJ, Sizemore HE, Wehrle K, Miller CLW, Fraley ME, Mullins AK, Guy AR, Phizicky EM, Guy MP. Identification of a Trm732 Motif Required for 2'--methylation of the tRNA Anticodon Loop by Trm7. Acs Omega. 7: 13667-13675. PMID 35559166 DOI: 10.1021/acsomega.1c07231  0.354
2021 Han L, Marcus E, Phizicky EM. A semi-quantitative pull-down assay to study tRNA substrate specificity of modification enzymes. Methods in Enzymology. 658: 359-377. PMID 34517954 DOI: 10.1016/bs.mie.2021.06.010  0.34
2020 De Zoysa T, Phizicky EM. Hypomodified tRNA in evolutionarily distant yeasts can trigger rapid tRNA decay to activate the general amino acid control response, but with different consequences. Plos Genetics. 16: e1008893. PMID 32841241 DOI: 10.1371/Journal.Pgen.1008893  0.396
2019 Payea MJ, Hauke AC, De Zoysa T, Phizicky EM. Mutations in the anticodon stem of tRNA cause accumulation and Met22-dependent decay of pre-tRNA in yeast. Rna (New York, N.Y.). PMID 31619505 DOI: 10.1261/Rna.073155.119  0.386
2019 Ramos J, Han L, Li Y, Hagelskamp F, Kellner SM, Alkuraya FS, Phizicky EM, Fu D. Formation of tRNA wobble inosine in humans is disrupted by a millennia-old mutation causing intellectual disability. Molecular and Cellular Biology. PMID 31263000 DOI: 10.1128/Mcb.00203-19  0.372
2019 Shaheen R, Tasak M, Maddirevula S, Abdel-Salam GMH, Sayed ISM, Alazami AM, Al-Sheddi T, Alobeid E, Phizicky EM, Alkuraya FS. PUS7 mutations impair pseudouridylation in humans and cause intellectual disability and microcephaly. Human Genetics. PMID 30778726 DOI: 10.1007/S00439-019-01980-3  0.349
2018 Han L, Phizicky EM. A rationale for tRNA modification circuits in the anticodon loop. Rna (New York, N.Y.). PMID 30026310 DOI: 10.1261/Rna.067736.118  0.346
2018 Zimmerman SM, Kon Y, Hauke AC, Ruiz BY, Fields S, Phizicky EM. Conditional accumulation of toxic tRNAs to cause amino acid misincorporation. Nucleic Acids Research. PMID 30007351 DOI: 10.1093/Nar/Gky623  0.394
2018 Han L, Guy MP, Kon Y, Phizicky EM. Lack of 2'-O-methylation in the tRNA anticodon loop of two phylogenetically distant yeast species activates the general amino acid control pathway. Plos Genetics. 14: e1007288. PMID 29596413 DOI: 10.1371/Journal.Pgen.1007288  0.41
2017 Payea MJ, Sloma MF, Kon Y, Young DL, Guy MP, Zhang X, De Zoysa T, Fields S, Mathews DH, Phizicky EM. Widespread temperature sensitivity and tRNA decay due to mutations in a yeast tRNA. Rna (New York, N.Y.). PMID 29259051 DOI: 10.1261/Rna.064642.117  0.342
2017 Hrabeta-Robinson E, Marcus E, Cozen AE, Phizicky EM, Lowe TM. High-Throughput Small RNA Sequencing Enhanced by AlkB-Facilitated RNA de-Methylation (ARM-Seq). Methods in Molecular Biology (Clifton, N.J.). 1562: 231-243. PMID 28349464 DOI: 10.1007/978-1-4939-6807-7_15  0.406
2016 Han L, Marcus E, D'Silva S, Phizicky EM. S. cerevisiae Trm140 has two recognition modes for 3-methylcytidine modification of the anticodon loop of tRNA substrates. Rna (New York, N.Y.). PMID 28003514 DOI: 10.1261/Rna.059667.116  0.443
2016 Patra B, Kon Y, Yadav G, Sevold AW, Frumkin JP, Vallabhajosyula RR, Hintze A, Østman B, Schossau J, Bhan A, Marzolf B, Tamashiro JK, Kaur A, Baliga NS, Grayhack EJ, ... ... Phizicky EM, et al. A genome wide dosage suppressor network reveals genomic robustness. Nucleic Acids Research. PMID 27899637 DOI: 10.1093/Nar/Gkw1148  0.386
2016 Shaheen R, Han L, Faqeih E, Ewida N, Alobeid E, Phizicky EM, Alkuraya FS. A homozygous truncating mutation in PUS3 expands the role of tRNA modification in normal cognition. Human Genetics. PMID 27055666 DOI: 10.1007/S00439-016-1665-7  0.342
2015 Shaheen R, Abdel-Salam GM, Guy MP, Alomar R, Abdel-Hamid MS, Afifi HH, Ismail SI, Emam BA, Phizicky EM, Alkuraya FS. Mutation in WDR4 impairs tRNA m(7)G46 methylation and causes a distinct form of microcephalic primordial dwarfism. Genome Biology. 16: 210. PMID 26416026 DOI: 10.1186/S13059-015-0779-X  0.365
2015 Guy MP, Shaw M, Weiner CL, Hobson L, Stark Z, Rose K, Kalscheuer VM, Gecz J, Phizicky EM. Defects in tRNA Anticodon Loop 2'-O-Methylation Are Implicated in Nonsyndromic X-Linked Intellectual Disability due to Mutations in FTSJ1. Human Mutation. 36: 1176-87. PMID 26310293 DOI: 10.1002/Humu.22897  0.413
2015 Payea MJ, Guy MP, Phizicky EM. Methodology for the High-Throughput Identification and Characterization of tRNA Variants That Are Substrates for a tRNA Decay Pathway. Methods in Enzymology. 560: 1-17. PMID 26253963 DOI: 10.1016/Bs.Mie.2015.03.003  0.433
2015 Cozen AE, Quartley E, Holmes AD, Hrabeta-Robinson E, Phizicky EM, Lowe TM. ARM-seq: AlkB-facilitated RNA methylation sequencing reveals a complex landscape of modified tRNA fragments. Nature Methods. 12: 879-84. PMID 26237225 DOI: 10.1038/Nmeth.3508  0.428
2015 Phizicky EM, Hopper AK. tRNA processing, modification, and subcellular dynamics: past, present, and future. Rna (New York, N.Y.). 21: 483-5. PMID 25780105 DOI: 10.1261/Rna.049932.115  0.408
2015 Han L, Kon Y, Phizicky EM. Functional importance of Ψ38 and Ψ39 in distinct tRNAs, amplified for tRNAGln(UUG) by unexpected temperature sensitivity of the s2U modification in yeast. Rna (New York, N.Y.). 21: 188-201. PMID 25505024 DOI: 10.1261/Rna.048173.114  0.387
2015 Guy MP, Phizicky EM. Conservation of an intricate circuit for crucial modifications of the tRNAPhe anticodon loop in eukaryotes. Rna (New York, N.Y.). 21: 61-74. PMID 25404562 DOI: 10.1261/Rna.047639.114  0.456
2014 Guy MP, Phizicky EM. Two-subunit enzymes involved in eukaryotic post-transcriptional tRNA modification. Rna Biology. 11: 1608-18. PMID 25625329 DOI: 10.1080/15476286.2015.1008360  0.461
2014 Pop C, Rouskin S, Ingolia NT, Han L, Phizicky EM, Weissman JS, Koller D. Causal signals between codon bias, mRNA structure, and the efficiency of translation and elongation. Molecular Systems Biology. 10: 770. PMID 25538139 DOI: 10.15252/Msb.20145524  0.375
2014 Zhang X, Walker RC, Phizicky EM, Mathews DH. Influence of Sequence and Covalent Modifications on Yeast tRNA Dynamics. Journal of Chemical Theory and Computation. 10: 3473-3483. PMID 25136272 DOI: 10.1021/Ct500107Y  0.389
2014 Guy MP, Young DL, Payea MJ, Zhang X, Kon Y, Dean KM, Grayhack EJ, Mathews DH, Fields S, Phizicky EM. Identification of the determinants of tRNA function and susceptibility to rapid tRNA decay by high-throughput in vivo analysis. Genes & Development. 28: 1721-32. PMID 25085423 DOI: 10.1101/Gad.245936.114  0.434
2013 Grant TD, Luft JR, Wolfley JR, Snell ME, Tsuruta H, Corretore S, Quartley E, Phizicky EM, Grayhack EJ, Snell EH. The structure of yeast glutaminyl-tRNA synthetase and modeling of its interaction with tRNA. Journal of Molecular Biology. 425: 2480-93. PMID 23583912 DOI: 10.1016/J.Jmb.2013.03.043  0.374
2013 Preston MA, D'Silva S, Kon Y, Phizicky EM. tRNAHis 5-methylcytidine levels increase in response to several growth arrest conditions in Saccharomyces cerevisiae. Rna (New York, N.Y.). 19: 243-56. PMID 23249748 DOI: 10.1261/Rna.035808.112  0.344
2012 Guy MP, Podyma BM, Preston MA, Shaheen HH, Krivos KL, Limbach PA, Hopper AK, Phizicky EM. Yeast Trm7 interacts with distinct proteins for critical modifications of the tRNAPhe anticodon loop. Rna (New York, N.Y.). 18: 1921-33. PMID 22912484 DOI: 10.1261/Rna.035287.112  0.443
2012 Dewe JM, Whipple JM, Chernyakov I, Jaramillo LN, Phizicky EM. The yeast rapid tRNA decay pathway competes with elongation factor 1A for substrate tRNAs and acts on tRNAs lacking one or more of several modifications. Rna (New York, N.Y.). 18: 1886-96. PMID 22895820 DOI: 10.1261/Rna.033654.112  0.435
2012 Grant TD, Snell EH, Luft JR, Quartley E, Corretore S, Wolfley JR, Snell ME, Hadd A, Perona JJ, Phizicky EM, Grayhack EJ. Structural conservation of an ancient tRNA sensor in eukaryotic glutaminyl-tRNA synthetase. Nucleic Acids Research. 40: 3723-31. PMID 22180531 DOI: 10.1093/Nar/Gkr1223  0.432
2011 Wilusz JE, Whipple JM, Phizicky EM, Sharp PA. tRNAs marked with CCACCA are targeted for degradation. Science (New York, N.Y.). 334: 817-21. PMID 22076379 DOI: 10.1126/Science.1213671  0.429
2011 Whipple JM, Lane EA, Chernyakov I, D'Silva S, Phizicky EM. The yeast rapid tRNA decay pathway primarily monitors the structural integrity of the acceptor and T-stems of mature tRNA. Genes & Development. 25: 1173-84. PMID 21632824 DOI: 10.1101/Gad.2050711  0.445
2011 D'Silva S, Haider SJ, Phizicky EM. A domain of the actin binding protein Abp140 is the yeast methyltransferase responsible for 3-methylcytidine modification in the tRNA anti-codon loop. Rna (New York, N.Y.). 17: 1100-10. PMID 21518804 DOI: 10.1261/Rna.2652611  0.474
2010 Phizicky EM, Hopper AK. tRNA biology charges to the front. Genes & Development. 24: 1832-60. PMID 20810645 DOI: 10.1101/Gad.1956510  0.392
2010 Preston MA, Phizicky EM. The requirement for the highly conserved G-1 residue of Saccharomyces cerevisiae tRNAHis can be circumvented by overexpression of tRNAHis and its synthetase. Rna (New York, N.Y.). 16: 1068-77. PMID 20360392 DOI: 10.1261/Rna.2087510  0.458
2010 Murthi A, Shaheen HH, Huang HY, Preston MA, Lai TP, Phizicky EM, Hopper AK. Regulation of tRNA bidirectional nuclear-cytoplasmic trafficking in Saccharomyces cerevisiae. Molecular Biology of the Cell. 21: 639-49. PMID 20032305 DOI: 10.1091/Mbc.E09-07-0551  0.375
2010 Phizicky EM, Alfonzo JD. Do all modifications benefit all tRNAs? Febs Letters. 584: 265-71. PMID 19931536 DOI: 10.1016/J.Febslet.2009.11.049  0.401
2009 Quartley E, Alexandrov A, Mikucki M, Buckner FS, Hol WG, DeTitta GT, Phizicky EM, Grayhack EJ. Heterologous expression of L. major proteins in S. cerevisiae: a test of solubility, purity, and gene recoding. Journal of Structural and Functional Genomics. 10: 233-47. PMID 19701618 DOI: 10.1007/S10969-009-9068-9  0.357
2008 Chernyakov I, Baker MA, Grayhack EJ, Phizicky EM. Chapter 11. Identification and analysis of tRNAs that are degraded in Saccharomyces cerevisiae due to lack of modifications. Methods in Enzymology. 449: 221-37. PMID 19215761 DOI: 10.1016/S0076-6879(08)02411-7  0.412
2008 Jackman JE, Grayhack EJ, Phizicky EM. The use of Saccharomyces cerevisiae proteomic libraries to identify RNA-modifying proteins. Methods in Molecular Biology (Clifton, N.J.). 488: 383-93. PMID 18982304 DOI: 10.1007/978-1-60327-475-3_25  0.69
2008 Phizicky EM. Waste not, want not: a case for tRNA repair. Nature Structural & Molecular Biology. 15: 783-4. PMID 18679433 DOI: 10.1038/Nsmb0808-783  0.407
2008 Merritt EA, Holmes M, Buckner FS, Van Voorhis WC, Quartly E, Phizicky EM, Lauricella A, Luft J, DeTitta G, Neely H, Zucker F, Hol WG. Structure of a Trypanosoma brucei alpha/beta-hydrolase fold protein with unknown function. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 64: 474-8. PMID 18540054 DOI: 10.1107/S174430910801141X  0.323
2008 Chernyakov I, Whipple JM, Kotelawala L, Grayhack EJ, Phizicky EM. Degradation of several hypomodified mature tRNA species in Saccharomyces cerevisiae is mediated by Met22 and the 5'-3' exonucleases Rat1 and Xrn1. Genes & Development. 22: 1369-80. PMID 18443146 DOI: 10.1101/Gad.1654308  0.416
2008 Jackman JE, Phizicky EM. Identification of critical residues for G-1 addition and substrate recognition by tRNA(His) guanylyltransferase. Biochemistry. 47: 4817-25. PMID 18366186 DOI: 10.1021/Bi702517Q  0.715
2008 Kotelawala L, Grayhack EJ, Phizicky EM. Identification of yeast tRNA Um(44) 2'-O-methyltransferase (Trm44) and demonstration of a Trm44 role in sustaining levels of specific tRNA(Ser) species. Rna (New York, N.Y.). 14: 158-69. PMID 18025252 DOI: 10.1261/Rna.811008  0.475
2007 Jackman JE, Kotelawala L, Grayhack EJ, Phizicky EM. Identification and characterization of modification enzymes by biochemical analysis of the proteome. Methods in Enzymology. 425: 139-52. PMID 17673082 DOI: 10.1016/S0076-6879(07)25006-2  0.682
2007 Malkowski MG, Quartley E, Friedman AE, Babulski J, Kon Y, Wolfley J, Said M, Luft JR, Phizicky EM, DeTitta GT, Grayhack EJ. Blocking S-adenosylmethionine synthesis in yeast allows selenomethionine incorporation and multiwavelength anomalous dispersion phasing. Proceedings of the National Academy of Sciences of the United States of America. 104: 6678-83. PMID 17426150 DOI: 10.1073/Pnas.0610337104  0.38
2007 Wilkinson ML, Crary SM, Jackman JE, Grayhack EJ, Phizicky EM. The 2'-O-methyltransferase responsible for modification of yeast tRNA at position 4. Rna (New York, N.Y.). 13: 404-13. PMID 17242307 DOI: 10.1261/Rna.399607  0.679
2006 Phizicky EM, Grayhack EJ. Proteome-scale analysis of biochemical activity. Critical Reviews in Biochemistry and Molecular Biology. 41: 315-27. PMID 16911958 DOI: 10.1080/10409230600872872  0.34
2006 Jackman JE, Phizicky EM. tRNAHis guanylyltransferase catalyzes a 3'-5' polymerization reaction that is distinct from G-1 addition. Proceedings of the National Academy of Sciences of the United States of America. 103: 8640-5. PMID 16731615 DOI: 10.1073/Pnas.0603068103  0.705
2006 Jackman JE, Phizicky EM. tRNAHis guanylyltransferase adds G-1 to the 5' end of tRNAHis by recognition of the anticodon, one of several features unexpectedly shared with tRNA synthetases. Rna (New York, N.Y.). 12: 1007-14. PMID 16625026 DOI: 10.1261/Rna.54706  0.72
2006 Arakaki T, Le Trong I, Phizicky E, Quartley E, DeTitta G, Luft J, Lauricella A, Anderson L, Kalyuzhniy O, Worthey E, Myler PJ, Kim D, Baker D, Hol WG, Merritt EA. Structure of Lmaj006129AAA, a hypothetical protein from Leishmania major. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 175-9. PMID 16511295 DOI: 10.1107/S1744309106005902  0.332
2006 Alexandrov A, Chernyakov I, Gu W, Hiley SL, Hughes TR, Grayhack EJ, Phizicky EM. Rapid tRNA decay can result from lack of nonessential modifications. Molecular Cell. 21: 87-96. PMID 16387656 DOI: 10.1016/J.Molcel.2005.10.036  0.459
2005 Gelperin DM, White MA, Wilkinson ML, Kon Y, Kung LA, Wise KJ, Lopez-Hoyo N, Jiang L, Piccirillo S, Yu H, Gerstein M, Dumont ME, Phizicky EM, Snyder M, Grayhack EJ. Biochemical and genetic analysis of the yeast proteome with a movable ORF collection. Genes & Development. 19: 2816-26. PMID 16322557 DOI: 10.1101/Gad.1362105  0.367
2005 Gu W, Hurto RL, Hopper AK, Grayhack EJ, Phizicky EM. Depletion of Saccharomyces cerevisiae tRNA(His) guanylyltransferase Thg1p leads to uncharged tRNAHis with additional m(5)C. Molecular and Cellular Biology. 25: 8191-201. PMID 16135808 DOI: 10.1128/Mcb.25.18.8191-8201.2005  0.438
2005 Phizicky EM. Have tRNA, will travel. Proceedings of the National Academy of Sciences of the United States of America. 102: 11127-8. PMID 16061803 DOI: 10.1073/Pnas.0504843102  0.403
2005 Cartlidge RA, Knebel A, Peggie M, Alexandrov A, Phizicky EM, Cohen P. The tRNA methylase METTL1 is phosphorylated and inactivated by PKB and RSK in vitro and in cells. The Embo Journal. 24: 1696-705. PMID 15861136 DOI: 10.1038/Sj.Emboj.7600648  0.301
2005 Alexandrov A, Grayhack EJ, Phizicky EM. tRNA m7G methyltransferase Trm8p/Trm82p: evidence linking activity to a growth phenotype and implicating Trm82p in maintaining levels of active Trm8p. Rna (New York, N.Y.). 11: 821-30. PMID 15811913 DOI: 10.1261/Rna.2030705  0.419
2005 Shull NP, Spinelli SL, Phizicky EM. A highly specific phosphatase that acts on ADP-ribose 1''-phosphate, a metabolite of tRNA splicing in Saccharomyces cerevisiae. Nucleic Acids Research. 33: 650-60. PMID 15684411 DOI: 10.1093/Nar/Gki211  0.404
2005 Hiley SL, Jackman J, Babak T, Trochesset M, Morris QD, Phizicky E, Hughes TR. Detection and discovery of RNA modifications using microarrays. Nucleic Acids Research. 33: e2. PMID 15640439 DOI: 10.1093/Nar/Gni002  0.684
2005 Steiger MA, Jackman JE, Phizicky EM. Analysis of 2'-phosphotransferase (Tpt1p) from Saccharomyces cerevisiae: evidence for a conserved two-step reaction mechanism. Rna (New York, N.Y.). 11: 99-106. PMID 15611300 DOI: 10.1261/Rna.7194605  0.713
2004 Alexandrov A, Vignali M, LaCount DJ, Quartley E, de Vries C, De Rosa D, Babulski J, Mitchell SF, Schoenfeld LW, Fields S, Hol WG, Dumont ME, Phizicky EM, Grayhack EJ. A facile method for high-throughput co-expression of protein pairs. Molecular & Cellular Proteomics : McP. 3: 934-8. PMID 15240823 DOI: 10.1074/Mcp.T400008-Mcp200  0.348
2004 Xing F, Hiley SL, Hughes TR, Phizicky EM. The specificities of four yeast dihydrouridine synthases for cytoplasmic tRNAs. The Journal of Biological Chemistry. 279: 17850-60. PMID 14970222 DOI: 10.1074/Jbc.M401221200  0.42
2003 Gu W, Jackman JE, Lohan AJ, Gray MW, Phizicky EM. tRNAHis maturation: an essential yeast protein catalyzes addition of a guanine nucleotide to the 5' end of tRNAHis. Genes & Development. 17: 2889-901. PMID 14633974 DOI: 10.1101/Gad.1148603  0.711
2003 Jackman JE, Montange RK, Malik HS, Phizicky EM. Identification of the yeast gene encoding the tRNA m1G methyltransferase responsible for modification at position 9. Rna (New York, N.Y.). 9: 574-85. PMID 12702816 DOI: 10.1261/Rna.5070303  0.681
2003 Phizicky E, Bastiaens PIH, Zhu H, Snyder M, Fields S. Protein analysis on a proteomic scale Nature. 422: 208-215. PMID 12634794 DOI: 10.1038/Nature01512  0.347
2003 Hopper AK, Phizicky EM. tRNA transfers to the limelight. Genes & Development. 17: 162-80. PMID 12533506 DOI: 10.1101/Gad.1049103  0.408
2002 Alexandrov A, Martzen MR, Phizicky EM. Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA. Rna (New York, N.Y.). 8: 1253-66. PMID 12403464 DOI: 10.1017/S1355838202024019  0.451
2002 Phizicky EM, Martzen MR, McCraith SM, Spinelli SL, Xing F, Shull NP, Van Slyke C, Montagne RK, Torres FM, Fields S, Grayhack EJ. Biochemical genomics approach to map activities to genes. Methods in Enzymology. 350: 546-59. PMID 12073335 DOI: 10.1016/S0076-6879(02)50984-8  0.365
2002 Xing F, Martzen MR, Phizicky EM. A conserved family of Saccharomyces cerevisiae synthases effects dihydrouridine modification of tRNA. Rna (New York, N.Y.). 8: 370-81. PMID 12003496 DOI: 10.1017/S1355838202029825  0.526
2001 Steiger MA, Kierzek R, Turner DH, Phizicky EM. Substrate recognition by a yeast 2'-phosphotransferase involved in tRNA splicing and by its Escherichia coli homolog. Biochemistry. 40: 14098-105. PMID 11705403 DOI: 10.1021/Bi011388T  0.448
2001 Grayhack EJ, Phizicky EM. Genomic analysis of biochemical function. Current Opinion in Chemical Biology. 5: 34-9. PMID 11166645 DOI: 10.1016/S1367-5931(00)00169-1  0.392
2000 Polevoda B, Martzen MR, Das B, Phizicky EM, Sherman F. Cytochrome c methyltransferase, Ctm1p, of yeast. The Journal of Biological Chemistry. 275: 20508-13. PMID 10791961 DOI: 10.1074/Jbc.M001891200  0.318
1999 Martzen MR, McCraith SM, Spinelli SL, Torres FM, Fields S, Grayhack EJ, Phizicky EM. A biochemical genomics approach for identifying genes by the activity of their products. Science (New York, N.Y.). 286: 1153-5. PMID 10550052 DOI: 10.1126/Science.286.5442.1153  0.371
1999 Spinelli SL, Kierzek R, Turner DH, Phizicky EM. Transient ADP-ribosylation of a 2'-phosphate implicated in its removal from ligated tRNA during splicing in yeast. The Journal of Biological Chemistry. 274: 2637-44. PMID 9915792 DOI: 10.1074/Jbc.274.5.2637  0.498
1998 Spinelli SL, Malik HS, Consaul SA, Phizicky EM. A functional homolog of a yeast tRNA splicing enzyme is conserved in higher eukaryotes and in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 95: 14136-41. PMID 9826666 DOI: 10.1073/Pnas.95.24.14136  0.503
1998 Robinson MK, Phizicky EM. Purification and assay of the Ptc1/Tpd1 protein phosphatase 2C from the yeast Saccharomyces cerevisiae. Methods in Molecular Biology (Clifton, N.J.). 93: 235-42. PMID 9664541 DOI: 10.1385/0-89603-468-2:235  0.358
1997 Spinelli SL, Consaul SA, Phizicky EM. A conditional lethal yeast phosphotransferase (tpt1) mutant accumulates tRNAs with a 2'-phosphate and an undermodified base at the splice junction. Rna (New York, N.Y.). 3: 1388-400. PMID 9404890  0.426
1997 Culver GM, McCraith SM, Consaul SA, Stanford DR, Phizicky EM. A 2'-phosphotransferase implicated in tRNA splicing is essential in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 272: 13203-10. PMID 9148937 DOI: 10.1074/Jbc.272.20.13203  0.46
1995 Phizicky EM, Fields S. Protein-protein interactions: methods for detection and analysis. Microbiological Reviews. 59: 94-123. PMID 7708014 DOI: 10.1128/Mmbr.59.1.94-123.1995  0.334
1994 Robinson MK, van Zyl WH, Phizicky EM, Broach JR. TPD1 of Saccharomyces cerevisiae encodes a protein phosphatase 2C-like activity implicated in tRNA splicing and cell separation. Molecular and Cellular Biology. 14: 3634-45. PMID 8196609 DOI: 10.1128/Mcb.14.6.3634  0.44
1993 Phizicky EM, Greer CL. Pre-tRNA splicing: variation on a theme or exception to the rule? Trends in Biochemical Sciences. 18: 31-4. PMID 8438235 DOI: 10.1016/0968-0004(93)90085-2  0.383
1993 Culver GM, McCraith SM, Zillmann M, Kierzek R, Michaud N, LaReau RD, Turner DH, Phizicky EM. An NAD derivative produced during transfer RNA splicing: ADP-ribose 1"-2" cyclic phosphate. Science (New York, N.Y.). 261: 206-8. PMID 8392224 DOI: 10.1126/Science.8392224  0.415
1992 Zillmann M, Gorovsky MA, Phizicky EM. HeLa cells contain a 2'-phosphate-specific phosphotransferase similar to a yeast enzyme implicated in tRNA splicing. The Journal of Biological Chemistry. 267: 10289-94. PMID 1316896  0.331
1991 Zillmann M, Gorovsky MA, Phizicky EM. Conserved mechanism of tRNA splicing in eukaryotes. Molecular and Cellular Biology. 11: 5410-6. PMID 1922054 DOI: 10.1128/Mcb.11.11.5410  0.454
1990 Xu Q, Phizicky EM, Greer CL, Abelson JN. Purification of yeast transfer RNA ligase. Methods in Enzymology. 181: 463-71. PMID 2166217 DOI: 10.1016/0076-6879(90)81144-J  0.481
1990 McCraith SM, Phizicky EM. A highly specific phosphatase from Saccharomyces cerevisiae implicated in tRNA splicing. Molecular and Cellular Biology. 10: 1049-55. PMID 2154680 DOI: 10.1128/Mcb.10.3.1049  0.468
1988 Westaway SK, Phizicky EM, Abelson J. Structure and function of the yeast tRNA ligase gene. The Journal of Biological Chemistry. 263: 3171-6. PMID 3277966  0.368
1986 Phizicky EM, Schwartz RC, Abelson J. Saccharomyces cerevisiae tRNA ligase. Purification of the protein and isolation of the structural gene. The Journal of Biological Chemistry. 261: 2978-86. PMID 3512545  0.361
1982 Roberts JW, Phizicky EM, Burbee DG, Roberts CW, Moreau PL. A brief consideration of the SOS inducing signal. Biochimie. 64: 805-7. PMID 6814531 DOI: 10.1016/S0300-9084(82)80133-8  0.521
1981 Phizicky EM, Roberts JW. Induction of SOS functions: regulation of proteolytic activity of E. coli RecA protein by interaction with DNA and nucleoside triphosphate. Cell. 25: 259-67. PMID 7023697 DOI: 10.1016/0092-8674(81)90251-8  0.555
1980 Phizicky EM, Roberts JW. Kinetics of RecA protein-directed inactivation of repressors of phage lambda and phage P22. Journal of Molecular Biology. 139: 319-28. PMID 6449596 DOI: 10.1016/0022-2836(80)90133-3  0.537
1979 Roberts JW, Roberts CW, Craig NL, Phizicky EM. Activity of the Escherichia coli recA-gene product. Cold Spring Harbor Symposia On Quantitative Biology. 43: 917-20. PMID 158477 DOI: 10.1101/Sqb.1979.043.01.100  0.647
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