M Imad Damaj - Publications

Affiliations: 
Virginia Commonwealth University, Richmond, VA, United States 
Area:
Pharmacology, Public Health

204 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Akinola LS, Gonzales J, Buzzi B, Mathews HL, Papke RL, Stitzel JA, Damaj MI. Investigating the role of nicotinic acetylcholine receptors in menthol's effects in mice. Drug and Alcohol Dependence. 257: 111262. PMID 38492255 DOI: 10.1016/j.drugalcdep.2024.111262  0.542
2024 Cheeks SN, Buzzi B, Valdez A, Mogul A, Damaj MI, Fowler CD. Cannabidiol as a potential cessation therapeutic: Effects on intravenous nicotine self-administration and withdrawal symptoms in mice. Neuropharmacology. 109833. PMID 38176534 DOI: 10.1016/j.neuropharm.2023.109833  0.555
2023 Richter K, Herz SM, Stokes C, Damaj MI, Grau V, Papke RL. Pharmacological profiles and anti-inflammatory activity of pCN-diEPP and mCN-diEPP, new alpha9alpha10 nicotinic receptor ligands. Neuropharmacology. 240: 109717. PMID 37758018 DOI: 10.1016/j.neuropharm.2023.109717  0.353
2023 Buzzi B, Koseli E, Alkhlaif Y, Parker A, Mustafa MA, Lichtman AH, Buczynski MW, Damaj MI. Differential roles of diacylglycerol lipase (DAGL) enzymes in nicotine withdrawal. Brain Research. 1817: 148483. PMID 37442250 DOI: 10.1016/j.brainres.2023.148483  0.503
2023 Buzzi B, Koseli E, Moncayo L, Shoaib M, Damaj MI. Role of neuronal nicotinic acetylcholine receptors in cannabinoid dependence. Pharmacological Research. 191: 106746. PMID 37001709 DOI: 10.1016/j.phrs.2023.106746  0.492
2023 Smith ML, Mignogna KM, Rokita JL, MacLeod L, Damaj MI, Miles MF. Identification of candidate genes for nicotine withdrawal in C57BL/6J × DBA/2J recombinant inbred mice. Genes, Brain, and Behavior. e12844. PMID 36781202 DOI: 10.1111/gbb.12844  0.417
2022 Akinola LS, Rahman Y, Ondo O, Cobb CO, Holt AK, Peace MR, Damaj MI. Impact of tobacco flavoring on oral nicotine consumption in C57BL/6J mice. Drug and Alcohol Dependence. 241: 109685. PMID 36370533 DOI: 10.1016/j.drugalcdep.2022.109685  0.515
2022 Akinola LS, Bagdas D, Alkhlaif Y, Jackson A, Gurdap CO, Rahimpour E, Carroll FI, Papke RL, Damaj MI. Pharmacological characterization of 5-iodo-A-85380, a β2-selective nicotinic receptor agonist, in mice. Journal of Psychopharmacology (Oxford, England). 36: 1280-1293. PMID 36321267 DOI: 10.1177/02698811221132214  0.549
2022 Akinola LS, Rahman Y, Ondo O, Gonzales J, Bagdas D, Jackson A, Davidson-Wert N, Damaj MI. Genotypic Differences in the Effects of Menthol on Nicotine Intake and Preference in Mice. Frontiers in Neuroscience. 16: 905330. PMID 35769694 DOI: 10.3389/fnins.2022.905330  0.609
2022 Caillaud M, Thompson D, Toma W, White A, Mann J, Roberts JL, Bigbee JW, Gewirtz DA, Damaj MI. Formulated Curcumin Prevents Paclitaxel-Induced Peripheral Neuropathy through Reduction in Neuroinflammation by Modulation of α7 Nicotinic Acetylcholine Receptors. Pharmaceutics. 14. PMID 35745868 DOI: 10.3390/pharmaceutics14061296  0.301
2021 Papke RL, De Biasi M, Damaj MI. Nicotine: understanding the big picture while also studying the details. Neuropharmacology. 108715. PMID 34271018 DOI: 10.1016/j.neuropharm.2021.108715  0.536
2021 Hamouda AK, Bautista MR, Akinola LS, Alkhlaif Y, Jackson A, Carper M, Toma WB, Garai S, Chen YC, Thakur GA, Fowler CD, Damaj MI. Potentiation of (α4)2(β2)3, but not (α4)3(β2)2, nicotinic acetylcholine receptors reduces nicotine self-administration and withdrawal symptoms. Neuropharmacology. 190: 108568. PMID 33878302 DOI: 10.1016/j.neuropharm.2021.108568  0.608
2020 Bagdas D, Jackson A, Carper M, Chen RY, Akinola LS, Damaj MI. Impact of menthol on nicotine intake and preference in mice: Concentration, sex, and age differences. Neuropharmacology. 108274. PMID 32827516 DOI: 10.1016/J.Neuropharm.2020.108274  0.633
2020 Deba F, Ramos K, Vannoy M, Munoz K, Akinola LS, Damaj MI, Hamouda AK. Examining the Effects of (α4)3(β2)2 Nicotinic Acetylcholine Receptor-Selective Positive Allosteric Modulator on Acute Thermal Nociception in Rats. Molecules (Basel, Switzerland). 25. PMID 32630476 DOI: 10.3390/Molecules25122923  0.564
2020 Bagdas D, Paris JJ, Carper M, Wodarski R, Rice ASC, Knapp PE, Hauser KF, Damaj MI. Conditional expression of HIV-1 Tat in the mouse alters the onset and progression of tonic, inflammatory, and neuropathic hypersensitivity in a sex-dependent manner. European Journal of Pain (London, England). PMID 32533878 DOI: 10.1002/Ejp.1618  0.305
2020 Muldoon PP, Akinola LS, Schlosburg JE, Lichtman AH, Sim-Selley LJ, Mahadevan A, Cravatt BF, Damaj MI. Inhibition of monoacylglycerol lipase reduces nicotine reward in the conditioned place preference test in male mice. Neuropharmacology. 108170. PMID 32479813 DOI: 10.1016/J.Neuropharm.2020.108170  0.643
2020 Toma W, Ulker E, Alqasem M, AlSharari SD, McIntosh JM, Damaj MI. Behavioral and Molecular Basis of Cholinergic Modulation of Pain: Focus on Nicotinic Acetylcholine Receptors. Current Topics in Behavioral Neurosciences. PMID 32468494 DOI: 10.1007/7854_2020_135  0.748
2020 Ulker E, Caillaud M, Patel T, White A, Rashid D, Alqasem M, Lichtman AH, Bryant CD, Damaj MI. C57BL/6 Substrain Differences in Formalin-Induced Pain-Like Behavioral Responses. Behavioural Brain Research. 112698. PMID 32428630 DOI: 10.1016/J.Bbr.2020.112698  0.321
2020 Ulker E, Toma W, White A, Uprety R, Majumdar S, Damaj MI. The antinociceptive effects of a dual kappa-delta opioid receptor agonist in the mouse formalin test. Behavioural Pharmacology. 31: 174-178. PMID 32168026 DOI: 10.1097/Fbp.0000000000000541  0.373
2019 Godin JR, Roy P, Quadri M, Bagdas D, Toma W, Narendrula-Kotha R, Kishta OA, Damaj MI, Horenstein NA, Papke RL, Simard AR. A silent agonist of α7 nicotinic acetylcholine receptors modulates inflammation ex vivo and attenuates EAE. Brain, Behavior, and Immunity. PMID 31874200 DOI: 10.1016/J.Bbi.2019.12.014  0.518
2019 Neddenriep B, Bagdas D, Contreras KM, Ditre JW, Wolstenholme JT, Miles MF, Damaj MI. Pharmacological mechanisms of alcohol analgesic-like properties in mouse models of acute and chronic pain. Neuropharmacology. 107793. PMID 31562845 DOI: 10.1016/J.Neuropharm.2019.107793  0.329
2019 Akinola LS, Mckiver B, Toma W, Zhu AZX, Tyndale RF, Kumar V, Damaj MI. C57BL/6 Substrain Differences in Pharmacological Effects after Acute and Repeated Nicotine Administration. Brain Sciences. 9. PMID 31546627 DOI: 10.3390/Brainsci9100244  0.62
2019 Xi ZX, Muldoon P, Wang XF, Bi GH, Damaj MI, Lichtman AH, Pertwee RG, Gardner EL. Δ -Tetrahydrocannabivarin has potent anti-nicotine effects in multiple rodent models of nicotine dependence. British Journal of Pharmacology. PMID 31454413 DOI: 10.1111/Bph.14844  0.519
2019 Jackson A, Alkhlaif Y, Papke RL, Brunzell DH, Damaj MI. Impact of modulation of the α7 nicotinic acetylcholine receptor on nicotine reward in the mouse conditioned place preference test. Psychopharmacology. PMID 31302720 DOI: 10.1007/s00213-019-05331-y  0.561
2019 Toma W, Kyte SL, Bagdas D, Jackson A, Meade JA, Rahman F, Chen ZJ, Del Fabbro E, Cantwell L, Kulkarni A, Thakur GA, Papke RL, Bigbee JW, Gewirtz DA, Damaj MI. The α7 nicotinic receptor silent agonist R-47 prevents and reverses paclitaxel-induced peripheral neuropathy in mice without tolerance or altering nicotine reward and withdrawal. Experimental Neurology. 113010. PMID 31299179 DOI: 10.1016/J.Expneurol.2019.113010  0.43
2019 Chen J, Loukola A, Gillespie NA, Peterson R, Jia P, Riley B, Maes H, Dick DM, Kendler KS, Damaj MI, Miles MF, Zhao Z, Li MD, Vink JM, Minica CC, et al. Genome-Wide Meta-Analyses of FTND and TTFC Phenotypes. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. PMID 31294817 DOI: 10.1093/Ntr/Ntz099  0.719
2019 Bagdas D, Diester CM, Riley J, Carper M, Alkhlaif Y, AlOmari D, Alayoubi H, Poklis JL, Damaj MI. Assessing nicotine dependence using an oral nicotine free-choice paradigm in mice. Neuropharmacology. 157: 107669. PMID 31220484 DOI: 10.1016/J.Neuropharm.2019.107669  0.676
2019 Jackson AB, Toma W, Contreras KM, Alkhlaif Y, Damaj MI. The β3 subunit of the nicotinic acetylcholine receptor is required for nicotine withdrawal-induced affective but not physical signs or nicotine reward in mice. Pharmacology, Biochemistry, and Behavior. PMID 31145916 DOI: 10.1016/J.Pbb.2019.05.003  0.682
2019 Bagdas D, Cam B, Gul Z, Scott MM, Tyndale RF, Buyukuysal RL, Damaj MI, Gurun MS. Impact of menthol on oral nicotine consumption in female and male Sprague Dawley rats. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. PMID 30753589 DOI: 10.1093/Ntr/Ntz019  0.555
2019 Bryant CD, Bagdas D, Goldberg LR, Khalefa T, Reed ER, Kirkpatrick SL, Kelliiher JC, Chen MM, Johnson WE, Mulligan MK, Damaj MI. C57BL/6 substrain differences in inflammatory and neuropathic nociception and genetic mapping of a major quantitative trait locus underlying acute thermal nociception. Molecular Pain. 1744806918825046. PMID 30632432 DOI: 10.1177/1744806918825046  0.344
2018 Bagdas D, AlSharari S, Roni MA, Campbell VC, Muldoon PP, Carroll FI, Damaj MI. Blockade of nicotinic acetylcholine receptor enhances the responsiveness to bupropion in the mouse forced swim test. Behavioural Brain Research. PMID 30552947 DOI: 10.1016/J.Bbr.2018.12.027  0.747
2018 Garai S, Raja KS, Papke RL, Deschamps JR, Damaj MI, Thakur GA. B-973, a Novel α7 nAChR Ago-PAM: Racemic and Asymmetric Synthesis, Electrophysiological Studies, and Evaluation. Acs Medicinal Chemistry Letters. 9: 1144-1148. PMID 30429960 DOI: 10.1021/Acsmedchemlett.8B00407  0.307
2018 Donvito G, Muldoon PP, Jackson KJ, Ahmad U, Zaveri NT, McIntosh JM, Chen X, Lichtman AH, Damaj MI. Neuronal nicotinic acetylcholine receptors mediate ∆ -THC dependence: Mouse and human studies. Addiction Biology. PMID 30378732 DOI: 10.1111/Adb.12691  0.845
2018 Quadri M, Bagdas D, Toma W, Stokes C, Horenstein NA, Damaj MI, Papke RL. The antinociceptive and anti-inflammatory properties of the α7 nAChR weak partial agonist -CF-diethyl--phenylpiperazine. The Journal of Pharmacology and Experimental Therapeutics. PMID 30111636 DOI: 10.1124/Jpet.118.249904  0.337
2018 Dawson A, Wolstenholme JT, Roni MA, Campbell VC, Jackson A, Slater C, Bagdas D, Perez EE, Bettinger JC, De Biasi M, Miles MF, Damaj MI. Knockout of alpha 5 nicotinic acetylcholine receptors subunit alters ethanol-mediated behavioral effects and reward in mice. Neuropharmacology. PMID 29944862 DOI: 10.1016/J.Neuropharm.2018.06.031  0.435
2018 Bagdas D, Alkhlaif Y, Jackson A, Carroll FI, Ditre JW, Damaj MI. New insights on the effects of varenicline on nicotine reward, withdrawal and hyperalgesia in mice. Neuropharmacology. 138: 72-79. PMID 29860196 DOI: 10.1016/J.Neuropharm.2018.05.025  0.675
2018 Bagdas D, Meade JA, Alkhlaif Y, Muldoon PP, Carroll FI, Damaj MI. Effect of nicotine and alpha-7 nicotinic modulators on visceral pain-induced conditioned place aversion in mice. European Journal of Pain (London, England). PMID 29633429 DOI: 10.1002/ejp.1231  0.51
2018 Donvito G, Piscitelli F, Muldoon P, Jackson A, Vitale RM, D'Aniello E, Giordano C, Ignatowska-Jankowska BM, Mustafa MA, Guida F, Petrie GN, Parker L, Smoum R, Sim-Selley L, Maione S, ... ... Damaj MI, et al. N-Oleoyl-glycine reduces nicotine reward and withdrawal in mice. Neuropharmacology. PMID 29567093 DOI: 10.1016/J.Neuropharm.2018.03.020  0.666
2018 Jackson A, Papke RL, Damaj MI. Pharmacological modulation of the α7 nicotinic acetylcholine receptor in a mouse model of mecamylamine-precipitated nicotine withdrawal. Psychopharmacology. PMID 29549391 DOI: 10.1007/S00213-018-4879-7  0.638
2018 Qian J, Mummalaneni S, Grider JR, Damaj MI, Lyall V. Nicotinic acetylcholine receptors (nAChRs) are expressed in Trpm5 positive taste receptor cells (TRCs). Plos One. 13: e0190465. PMID 29293602 DOI: 10.1371/Journal.Pone.0190465  0.521
2017 Fowler CD, Gipson CD, Kleykamp BA, Rupprecht LE, Harrell PT, Rees VW, Gould TJ, Oliver J, Bagdas D, Damaj MI, Schmidt HD, Duncan A, De Biasi M. Basic Science and Public Policy: Informed Regulation for Nicotine and Tobacco Products. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. PMID 29065200 DOI: 10.1093/Ntr/Ntx175  0.48
2017 Hamouda AK, Jackson A, Bagdas D, Damaj MI. Reversal of Nicotine Withdrawal Signs through Positive Allosteric Modulation of α4β2 Nicotinic Acetylcholine Receptors in Male Mice. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. PMID 29059422 DOI: 10.1093/Ntr/Ntx183  0.644
2017 Kyte SL, Toma W, Bagdas D, Meade JA, Schurman LD, Lichtman AH, Chen ZJ, Del Fabbro E, Fang X, Bigbee JW, Damaj MI, Gewirtz DA. Nicotine prevents and reverses paclitaxel-induced mechanical allodynia in a mouse model of CIPN. The Journal of Pharmacology and Experimental Therapeutics. PMID 29042416 DOI: 10.1124/Jpet.117.243972  0.573
2017 Bagdas D, Gurun MS, Flood P, Papke RL, Damaj MI. New Insights on Neuronal Nicotinic Acetylcholine Receptors as Targets for Pain and Inflammation: A Focus on α7 nAChRs. Current Neuropharmacology. PMID 28820052 DOI: 10.2174/1570159X15666170818102108  0.567
2017 Bagdas D, Ergun D, Jackson A, Toma W, Schulte MK, Damaj MI. Allosteric modulation of α4β2* nicotinic acetylcholine receptors: Desformylflustrabromine potentiates antiallodynic response of nicotine in a mouse model of neuropathic pain. European Journal of Pain (London, England). PMID 28809075 DOI: 10.1002/ejp.1092  0.53
2017 Owens RA, Mustafa MA, Ignatowska-Jankowska BM, Damaj MI, Beardsley PM, Wiley JL, Niphakis MJ, Cravatt BF, Lichtman AH. Inhibition of the endocannabinoid-regulating enzyme monoacylglycerol lipase elicits a CB1 receptor-mediated discriminative stimulus in mice. Neuropharmacology. PMID 28673548 DOI: 10.1016/J.Neuropharm.2017.06.032  0.388
2017 Papke RL, Stokes C, Damaj MI, Thakur GA, Manther K, Treinin M, Bagdas D, Kulkarni AR, Horenstein NA. Persistent activation of α7 nAChRs associated with stable induction of different desensitized states. British Journal of Pharmacology. PMID 28477386 DOI: 10.1111/Bph.13851  0.432
2017 Jackson A, Bagdas D, Muldoon PP, Lichtman AH, Carroll FI, Greenwald M, Miles MF, Damaj MI. In vivo interactions between α7 nicotinic acetylcholine receptor and nuclear peroxisome proliferator-activated receptor-α: Implication for nicotine dependence. Neuropharmacology. PMID 28279662 DOI: 10.1016/J.Neuropharm.2017.03.005  0.669
2017 Toma W, Kyte SL, Bagdas D, Alkhlaif Y, Alsharari SD, Lichtman AH, Chen ZJ, Del Fabbro E, Bigbee JW, Gewirtz DA, Damaj MI. Effects of paclitaxel on the development of neuropathy and affective behaviors in the mouse. Neuropharmacology. PMID 28237807 DOI: 10.1016/J.Neuropharm.2017.02.020  0.693
2017 Elhassan S, Bagdas D, Damaj MI. Effects of Nicotine Metabolites on Nicotine Withdrawal Behaviors in Mice. Nicotine & Tobacco Research. 19: 763-766. PMID 28199726 DOI: 10.1093/Ntr/Ntx045  0.667
2017 Kyte SL, Toma W, Thakur G, Damaj MI, Gewirtz DA. Abstract 986: Targeting nicotinic acetylcholine receptors for the prevention and reversal of chemotherapy-induced peripheral neuropathy Cancer Research. 77: 986-986. DOI: 10.1158/1538-7445.Am2017-986  0.583
2016 Ondachi PW, Castro AH, Sherman B, Luetje CW, Damaj MI, Mascarella SW, Navarro HA, Carroll FI. Synthesis, Nicotinic Acetylcholine Receptor Binding, In Vitro and In Vivo Pharmacological Properties of 2'-Fluoro-(substituted thiophenyl)deschloroepibatidine Analogs. Acs Chemical Neuroscience. PMID 27726337 DOI: 10.1021/Acschemneuro.6B00252  0.414
2016 Alsharari SD, Bagdas D, Akbarali HI, Lichtman PA, Raborn ES, Cabral GA, Carroll FI, McGee EA, Damaj MI. Sex differences and drug dose influence the role of the α7 nicotinic acetylcholine receptor in the Mouse Dextran Sodium Sulfate-Induced Colitis Model. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. PMID 27639096 DOI: 10.1093/Ntr/Ntw245  0.786
2016 Donvito G, Wilkerson JL, Damaj MI, Lichtman AH. Palmitoylethanolamide reverses paclitaxel-induced allodynia in mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 27608657 DOI: 10.1124/Jpet.116.236182  0.368
2016 Enga RM, Jackson A, Damaj MI, Beardsley PM. Oxycodone physical dependence and its oral self-administration in C57BL/6J mice. European Journal of Pharmacology. PMID 27393461 DOI: 10.1016/J.Ejphar.2016.07.006  0.381
2016 Arvaniti M, Jensen MM, Soni N, Wang H, Klein AB, Thiriet N, Pinborg LH, Muldoon PP, Wienecke J, Damaj MI, Kohlmeier KA, Gondré-Lewis MC, Mikkelsen JD, Thomsen MS. Functional interaction between Lypd6 and nicotinic acetylcholine receptors. Journal of Neurochemistry. PMID 27344019 DOI: 10.1111/Jnc.13718  0.541
2016 Ondachi PW, Castro AH, Luetje CW, Wageman CR, Marks MJ, Damaj MI, Mascarella SW, Navarro HA, Carroll FI. Synthesis, Nicotinic Acetylcholine Binding, In Vitro and In Vivo Pharmacological Properties of 2'-Fluoro-(carbamoylpyridinyl)deschloroepibatidine Analogs. Acs Chemical Neuroscience. PMID 27166021 DOI: 10.1021/Acschemneuro.6B00107  0.512
2016 Gade AR, Kang M, Khan F, Grider JR, Damaj MI, Dewey WL, Akbarali HI. Enhanced sensitivity of α3β4 nicotinic receptors in enteric neurons after chronic morphine: implication for opioid-induced constipation. The Journal of Pharmacology and Experimental Therapeutics. PMID 27068812 DOI: 10.1124/Jpet.116.233304  0.533
2016 Alajaji M, Lazenka MF, Kota D, Wise LE, YOUnis RM, Carroll FI, Levine A, Selley DE, Sim-Selley LJ, Damaj MI. Early adolescent nicotine exposure affects later-life cocaine reward in mice. Neuropharmacology. PMID 26808314 DOI: 10.1016/J.Neuropharm.2016.01.032  0.842
2016 Bowers MS, Jackson A, Maldoon PP, Damaj MI. N-acetylcysteine decreased nicotine reward-like properties and withdrawal in mice. Psychopharmacology. 233: 995-1003. PMID 26676982 DOI: 10.1007/s00213-015-4179-4  0.454
2016 Bagdas D, Muldoon PP, AlSharari S, Carroll FI, Negus SS, Damaj MI. Expression and pharmacological modulation of visceral pain-induced conditioned place aversion in mice. Neuropharmacology. 102: 236-43. PMID 26639043 DOI: 10.1016/J.Neuropharm.2015.11.024  0.696
2015 Alsharari SD, King JR, Nordman JC, Muldoon PP, Jackson A, Zhu AZ, Tyndale RF, Kabbani N, Damaj MI. Effects of Menthol on Nicotine Pharmacokinetic, Pharmacology and Dependence in Mice. Plos One. 10: e0137070. PMID 26355604 DOI: 10.1371/Journal.Pone.0137070  0.839
2015 Jackson KJ, Muldoon PP, Walters C, Damaj MI. Neuronal calcium/calmodulin-dependent protein kinase II mediates nicotine reward in the conditioned place preference test in mice. Behavioural Pharmacology. PMID 26292186 DOI: 10.1097/Fbp.0000000000000189  0.821
2015 Bagdas D, Targowska-Duda KM, López JJ, Perez EG, Arias HR, Damaj MI. The Antinociceptive and Antiinflammatory Properties of 3-furan-2-yl-N-p-tolyl-acrylamide, a Positive Allosteric Modulator of α7 Nicotinic Acetylcholine Receptors in Mice. Anesthesia and Analgesia. 121: 1369-77. PMID 26280585 DOI: 10.1213/Ane.0000000000000902  0.526
2015 Ondachi PW, Ye Z, Castro AH, Luetje CW, Damaj MI, Mascarella SW, Navarro HA, Carroll FI. Synthesis, nicotinic acetylcholine receptor binding, in vitro and in vivo pharmacology properties of 3'-(substituted pyridinyl)-deschloroepibatidine analogs. Bioorganic & Medicinal Chemistry. PMID 26233800 DOI: 10.1016/J.Bmc.2015.07.021  0.529
2015 Jackson KJ, Jackson A, Ivy Carroll F, Damaj MI. Effects of orally-bioavailable short-acting kappa opioid receptor-selective antagonist LY2456302 on nicotine withdrawal in mice. Neuropharmacology. PMID 26044637 DOI: 10.1016/J.Neuropharm.2015.05.023  0.834
2015 Bagdas D, AlSharari SD, Freitas K, Tracy M, Damaj MI. The role of alpha5 nicotinic acetylcholine receptors in mouse models of chronic inflammatory and neuropathic pain. Biochemical Pharmacology. 97: 590-600. PMID 25931144 DOI: 10.1016/J.Bcp.2015.04.013  0.776
2015 Carroll FI, Navarro HA, Mascarella SW, Castro AH, Luetje CW, Wageman CR, Marks MJ, Jackson A, Damaj MI. In Vitro and in Vivo Neuronal Nicotinic Receptor Properties of (+)- and (-)-Pyrido[3,4]homotropane [(+)- and (-)-PHT]: (+)-PHT Is a Potent and Selective Full Agonist at α6β2 Containing Neuronal Nicotinic Acetylcholine Receptors. Acs Chemical Neuroscience. 6: 920-6. PMID 25891987 DOI: 10.1021/Acschemneuro.5B00077  0.635
2015 Malcolm E, Carroll FI, Blough B, Damaj MI, Shoaib M. Examination of the metabolite hydroxybupropion in the reinforcing and aversive stimulus effects of nicotine in rats. Psychopharmacology. 232: 2763-71. PMID 25761841 DOI: 10.1007/s00213-015-3908-z  0.438
2015 Papke RL, Bagdas D, Kulkarni AR, Gould T, AlSharari SD, Thakur GA, Damaj MI. The analgesic-like properties of the alpha7 nAChR silent agonist NS6740 is associated with non-conducting conformations of the receptor. Neuropharmacology. 91: 34-42. PMID 25497451 DOI: 10.1016/J.Neuropharm.2014.12.002  0.738
2015 Gamage TF, Ignatowska-Jankowska BM, Muldoon PP, Cravatt BF, Damaj MI, Lichtman AH. Differential effects of endocannabinoid catabolic inhibitors on morphine withdrawal in mice. Drug and Alcohol Dependence. 146: 7-16. PMID 25479915 DOI: 10.1016/J.Drugalcdep.2014.11.015  0.34
2015 Jackson KJ, Muldoon PP, De Biasi M, Damaj MI. New mechanisms and perspectives in nicotine withdrawal. Neuropharmacology. 96: 223-34. PMID 25433149 DOI: 10.1016/J.Neuropharm.2014.11.009  0.802
2015 Muldoon PP, Chen J, Harenza JL, Abdullah RA, Sim-Selley LJ, Cravatt BF, Miles MF, Chen X, Lichtman AH, Damaj MI. Inhibition of monoacylglycerol lipase reduces nicotine withdrawal. British Journal of Pharmacology. 172: 869-82. PMID 25258021 DOI: 10.1111/Bph.12948  0.752
2015 Sanjakdar SS, Maldoon PP, Marks MJ, Brunzell DH, Maskos U, McIntosh JM, Bowers MS, Damaj MI. Differential roles of α6β2* and α4β2* neuronal nicotinic receptors in nicotine- and cocaine-conditioned reward in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 350-60. PMID 25035086 DOI: 10.1038/Npp.2014.177  0.6
2015 Alsharari SD, King JR, Nordman JC, Muldoon PP, Jackson A, Zhu AZX, Tyndale RF, Kabbani N, Damaj MI. Nicotine plasma levels in adult male ICR mouse after pre-treatment with vehicle or menthol in the withdrawal testing. Plos One. DOI: 10.1371/Journal.Pone.0137070.T004  0.737
2015 Alsharari SD, King JR, Nordman JC, Muldoon PP, Jackson A, Zhu AZX, Tyndale RF, Kabbani N, Damaj MI. Blockade of menthol’s effects on nicotine acute pharmacological responses after administration in mice. Plos One. DOI: 10.1371/Journal.Pone.0137070.T002  0.809
2015 Alsharari SD, King JR, Nordman JC, Muldoon PP, Jackson A, Zhu AZX, Tyndale RF, Kabbani N, Damaj MI. Impact of menthol treatment on nicotine pharmacokinetic parameters. Plos One. DOI: 10.1371/Journal.Pone.0137070.T001  0.768
2015 Alsharari SD, King JR, Nordman JC, Muldoon PP, Jackson A, Zhu AZX, Tyndale RF, Kabbani N, Damaj MI. Effects of menthol on nicotine withdrawal signs. (A) Elevated plus-maze test, (B) Somatic signs and in (C) Hyperalgesia. Plos One. DOI: 10.1371/Journal.Pone.0137070.G005  0.767
2015 Alsharari SD, King JR, Nordman JC, Muldoon PP, Jackson A, Zhu AZX, Tyndale RF, Kabbani N, Damaj MI. Effects of menthol pretreatment on nicotine-induced antinociception and hypothermia dose-response curves in mice. Plos One. DOI: 10.1371/Journal.Pone.0137070.G004  0.791
2015 Alsharari SD, King JR, Nordman JC, Muldoon PP, Jackson A, Zhu AZX, Tyndale RF, Kabbani N, Damaj MI. Time course of nicotine plasma concentrations in mice pretreated with menthol. Plos One. DOI: 10.1371/Journal.Pone.0137070.G001  0.761
2015 Bagdas D, AlSharari SD, Freitas K, Tracy M, Damaj MI. The role of alpha5 nicotinic acetylcholine receptors in mouse models of chronic inflammatory and neuropathic pain Biochemical Pharmacology. 97: 590-600. DOI: 10.1016/j.bcp.2015.04.013  0.761
2014 Flood P, Damaj MI. Nicotine is out: nicotinic agonists may have utility as analgesics. Anesthesia and Analgesia. 119: 232-3. PMID 25046780 DOI: 10.1213/Ane.0000000000000304  0.646
2014 Bagdas D, Muldoon PP, Zhu AZ, Tyndale RF, Damaj MI. Effects of methoxsalen, a CYP2A5/6 inhibitor, on nicotine dependence behaviors in mice. Neuropharmacology. 85: 67-72. PMID 24859605 DOI: 10.1016/J.Neuropharm.2014.05.006  0.668
2014 Muldoon PP, Jackson KJ, Perez E, Harenza JL, Molas S, Rais B, Anwar H, Zaveri NT, Maldonado R, Maskos U, McIntosh JM, Dierssen M, Miles MF, Chen X, De Biasi M, ... Damaj MI, et al. The α3β4* nicotinic ACh receptor subtype mediates physical dependence to morphine: mouse and human studies. British Journal of Pharmacology. 171: 3845-57. PMID 24750073 DOI: 10.1111/Bph.12741  0.811
2014 Carroll FI, Blough BE, Mascarella SW, Navarro HA, Lukas RJ, Damaj MI. Bupropion and bupropion analogs as treatments for CNS disorders. Advances in Pharmacology (San Diego, Calif.). 69: 177-216. PMID 24484978 DOI: 10.1016/B978-0-12-420118-7.00005-6  0.447
2014 Ondachi PW, Castro AH, Bartkowiak JM, Luetje CW, Damaj MI, Mascarella SW, Navarro HA, Carroll FI. Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2'-fluoro-3'-(substituted pyridinyl)-7-deschloroepibatidine analogues. Journal of Medicinal Chemistry. 57: 836-48. PMID 24428686 DOI: 10.1021/Jm401602P  0.3
2014 Harenza JL, Muldoon PP, De Biasi M, Damaj MI, Miles MF. Genetic variation within the Chrna7 gene modulates nicotine reward-like phenotypes in mice. Genes, Brain, and Behavior. 13: 213-25. PMID 24289814 DOI: 10.1111/gbb.12113  0.58
2014 Nordman JC, Muldoon P, Clark S, Damaj MI, Kabbani N. The α4 nicotinic receptor promotes CD4+ T-cell proliferation and a helper T-cell immune response. Molecular Pharmacology. 85: 50-61. PMID 24107512 DOI: 10.1124/Mol.113.088484  0.469
2014 Alsharari SD, Siu EC, Tyndale RF, Damaj MI. Pharmacokinetic and pharmacodynamics studies of nicotine after oral administration in mice: effects of methoxsalen, a CYP2A5/6 inhibitor. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 16: 18-25. PMID 23884323 DOI: 10.1093/ntr/ntt105  0.819
2013 Jackson KJ, Damaj MI. Calcium/calmodulin-dependent protein kinase IV mediates acute nicotine-induced antinociception in acute thermal pain tests. Behavioural Pharmacology. 24: 689-92. PMID 24196027 DOI: 10.1097/Fbp.0000000000000005  0.775
2013 AlSharari SD, Freitas K, Damaj MI. Functional role of alpha7 nicotinic receptor in chronic neuropathic and inflammatory pain: Studies in transgenic mice Biochemical Pharmacology. 86: 1201-1207. PMID 23811428 DOI: 10.1016/J.Bcp.2013.06.018  0.771
2013 Jackson KJ, Wang JB, Barbier E, Damaj MI, Chen X. The histidine triad nucleotide binding 1 protein is involved in nicotine reward and physical nicotine withdrawal in mice. Neuroscience Letters. 550: 129-33. PMID 23810802 DOI: 10.1016/J.Neulet.2013.06.027  0.858
2013 Ignatowska-Jankowska BM, Muldoon PP, Lichtman AH, Damaj MI. The cannabinoid CB2 receptor is necessary for nicotine-conditioned place preference, but not other behavioral effects of nicotine in mice. Psychopharmacology. 229: 591-601. PMID 23652588 DOI: 10.1007/S00213-013-3117-6  0.661
2013 Alajaji M, Bowers MS, Knackstedt L, Damaj MI. Effects of the beta-lactam antibiotic ceftriaxone on nicotine withdrawal and nicotine-induced reinstatement of preference in mice. Psychopharmacology. 228: 419-26. PMID 23503685 DOI: 10.1007/S00213-013-3047-3  0.569
2013 Dawson A, Miles MF, Damaj MI. The β2 nicotinic acetylcholine receptor subunit differentially influences ethanol behavioral effects in the mouse. Alcohol (Fayetteville, N.Y.). 47: 85-94. PMID 23419392 DOI: 10.1016/J.Alcohol.2012.12.004  0.508
2013 Jackson KJ, Sanjakdar SS, Muldoon PP, McIntosh JM, Damaj MI. The α3β4* nicotinic acetylcholine receptor subtype mediates nicotine reward and physical nicotine withdrawal signs independently of the α5 subunit in the mouse. Neuropharmacology. 70: 228-35. PMID 23416040 DOI: 10.1016/J.Neuropharm.2013.01.017  0.848
2013 Kendler KS, Myers J, Damaj MI, Chen X. Early smoking onset and risk for subsequent nicotine dependence: a monozygotic co-twin control study. The American Journal of Psychiatry. 170: 408-13. PMID 23318372 DOI: 10.1176/Appi.Ajp.2012.12030321  0.558
2013 Freitas K, Carroll FI, Damaj MI. The antinociceptive effects of nicotinic receptors α7-positive allosteric modulators in murine acute and tonic pain models. The Journal of Pharmacology and Experimental Therapeutics. 344: 264-75. PMID 23115222 DOI: 10.1124/Jpet.112.197871  0.527
2013 AlSharari SD, Akbarali HI, Abdullah RA, Shahab O, Auttachoat W, Ferreira GA, White KL, Lichtman AH, Cabral GA, Damaj MI. Novel insights on the effect of nicotine in a murine colitis model. The Journal of Pharmacology and Experimental Therapeutics. 344: 207-17. PMID 23115221 DOI: 10.1124/Jpet.112.198796  0.811
2013 Freitas K, Negus S, Carroll FI, Damaj MI. In vivo pharmacological interactions between a type II positive allosteric modulator of α7 nicotinic ACh receptors and nicotinic agonists in a murine tonic pain model British Journal of Pharmacology. 169: 567-579. PMID 23004024 DOI: 10.1111/j.1476-5381.2012.02226.x  0.514
2013 Muldoon PP, Lichtman AH, Parsons LH, Damaj MI. The role of fatty acid amide hydrolase inhibition in nicotine reward and dependence. Life Sciences. 92: 458-62. PMID 22705310 DOI: 10.1016/J.Lfs.2012.05.015  0.618
2013 Jackson KJ, McLaughlin JP, Carroll FI, Damaj MI. Effects of the kappa opioid receptor antagonist, norbinaltorphimine, on stress and drug-induced reinstatement of nicotine-conditioned place preference in mice. Psychopharmacology. 226: 763-8. PMID 22526543 DOI: 10.1007/S00213-012-2716-Y  0.702
2012 Jackson KJ, Sanjakdar SS, Chen X, Damaj MI. Nicotine reward and affective nicotine withdrawal signs are attenuated in calcium/calmodulin-dependent protein kinase IV knockout mice. Plos One. 7: e51154. PMID 23226481 DOI: 10.1371/Journal.Pone.0051154  0.861
2012 Jackson KJ, Wang JB, Barbier E, Chen X, Damaj MI. Acute behavioral effects of nicotine in male and female HINT1 knockout mice. Genes, Brain, and Behavior. 11: 993-1000. PMID 22827509 DOI: 10.1111/J.1601-183X.2012.00827.X  0.812
2012 Ondachi P, Castro A, Luetje CW, Damaj MI, Mascarella SW, Navarro HA, Carroll FI. Synthesis and nicotinic acetylcholine receptor in vitro and in vivo pharmacological properties of 2'-fluoro-3'-(substituted phenyl)deschloroepibatidine analogues of 2'-fluoro-3'-(4-nitrophenyl)deschloroepibatidine. Journal of Medicinal Chemistry. 55: 6512-22. PMID 22742586 DOI: 10.1021/Jm300575Y  0.499
2012 AlSharari SD, Carroll FI, McIntosh JM, Damaj MI. The antinociceptive effects of nicotinic partial agonists varenicline and sazetidine-A in murine acute and tonic pain models. The Journal of Pharmacology and Experimental Therapeutics. 342: 742-9. PMID 22678099 DOI: 10.1124/Jpet.112.194506  0.8
2012 George AA, Lucero LM, Damaj MI, Lukas RJ, Chen X, Whiteaker P. Function of human α3β4α5 nicotinic acetylcholine receptors is reduced by the α5(D398N) variant. The Journal of Biological Chemistry. 287: 25151-62. PMID 22665477 DOI: 10.1074/Jbc.M112.379339  0.699
2012 Grabus SD, Carroll FI, Damaj MI. Bupropion and its main metabolite reverse nicotine chronic tolerance in the mouse. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 14: 1356-61. PMID 22589419 DOI: 10.1093/ntr/nts088  0.493
2012 Tobey KM, Walentiny DM, Wiley JL, Carroll FI, Damaj MI, Azar MR, Koob GF, George O, Harris LS, Vann RE. Effects of the specific α4β2 nAChR antagonist, 2-fluoro-3-(4-nitrophenyl) deschloroepibatidine, on nicotine reward-related behaviors in rats and mice. Psychopharmacology. 223: 159-68. PMID 22526534 DOI: 10.1007/S00213-012-2703-3  0.527
2011 Jackson KJ, Chen X, Miles MF, Harenza J, Damaj MI. The neuropeptide galanin and variants in the GalR1 gene are associated with nicotine dependence. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 2339-48. PMID 21796100 DOI: 10.1038/Npp.2011.123  0.855
2011 Kota D, Sanjakdar S, Marks MJ, Khabour O, Alzoubi K, Damaj MI. Exploring behavioral and molecular mechanisms of nicotine reward in adolescent mice Biochemical Pharmacology. 82: 1008-1014. PMID 21708139 DOI: 10.1016/J.Bcp.2011.06.019  0.851
2011 Carroll FI, Muresan AZ, Blough BE, Navarro HA, Mascarella SW, Eaton JB, Huang X, Damaj MI, Lukas RJ. Synthesis of 2-(substituted phenyl)-3,5,5-trimethylmorpholine analogues and their effects on monoamine uptake, nicotinic acetylcholine receptor function, and behavioral effects of nicotine. Journal of Medicinal Chemistry. 54: 1441-8. PMID 21319801 DOI: 10.1021/Jm1014555  0.53
2011 George O, Lloyd A, Carroll FI, Damaj MI, Koob GF. Varenicline blocks nicotine intake in rats with extended access to nicotine self-administration. Psychopharmacology. 213: 715-22. PMID 20924754 DOI: 10.1007/S00213-010-2024-3  0.641
2010 Carroll FI, Blough BE, Mascarella SW, Navarro HA, Eaton JB, Lukas RJ, Damaj MI. Nicotinic acetylcholine receptor efficacy and pharmacological properties of 3-(substituted phenyl)-2β-substituted tropanes. Journal of Medicinal Chemistry. 53: 8345-53. PMID 21058665 DOI: 10.1021/jm100994w  0.506
2010 Zhang Y, Gilliam A, Maitra R, Damaj MI, Tajuba JM, Seltzman HH, Thomas BF. Synthesis and biological evaluation of bivalent ligands for the cannabinoid 1 receptor. Journal of Medicinal Chemistry. 53: 7048-60. PMID 20845959 DOI: 10.1021/Jm1006676  0.302
2010 Abdrakhmanova GR, Blough BE, Nesloney C, Navarro HA, Damaj MI, Carroll FI. In vitro and in vivo characterization of a novel negative allosteric modulator of neuronal nAChRs. Neuropharmacology. 59: 511-7. PMID 20633568 DOI: 10.1016/J.Neuropharm.2010.07.006  0.51
2010 Abdrakhmanova GR, AlSharari S, Kang M, Damaj MI, Akbarali HI. {alpha}7-nAChR-mediated suppression of hyperexcitability of colonic dorsal root ganglia neurons in experimental colitis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 299: G761-8. PMID 20595621 DOI: 10.1152/Ajpgi.00175.2010  0.78
2010 Damaj MI, Grabus SD, Navarro HA, Vann RE, Warner JA, King LS, Wiley JL, Blough BE, Lukas RJ, Carroll FI. Effects of hydroxymetabolites of bupropion on nicotine dependence behavior in mice. The Journal of Pharmacology and Experimental Therapeutics. 334: 1087-95. PMID 20576796 DOI: 10.1124/Jpet.110.166850  0.569
2010 Lukas RJ, Muresan AZ, Damaj MI, Blough BE, Huang X, Navarro HA, Mascarella SW, Eaton JB, Marxer-Miller SK, Carroll FI. Synthesis and characterization of in vitro and in vivo profiles of hydroxybupropion analogues: aids to smoking cessation. Journal of Medicinal Chemistry. 53: 4731-48. PMID 20509659 DOI: 10.1021/Jm1003232  0.43
2010 Jackson KJ, Marks MJ, Vann RE, Chen X, Gamage TF, Warner JA, Damaj MI. Role of alpha5 nicotinic acetylcholine receptors in pharmacological and behavioral effects of nicotine in mice. The Journal of Pharmacology and Experimental Therapeutics. 334: 137-46. PMID 20400469 DOI: 10.1124/Jpet.110.165738  0.798
2010 Jackson KJ, Carroll FI, Negus SS, Damaj MI. Effect of the selective kappa-opioid receptor antagonist JDTic on nicotine antinociception, reward, and withdrawal in the mouse. Psychopharmacology. 210: 285-94. PMID 20232057 DOI: 10.1007/S00213-010-1803-1  0.755
2010 Carroll FI, Blough BE, Mascarella SW, Navarro HA, Eaton JB, Lukas RJ, Damaj MI. Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for smoking cessation. Journal of Medicinal Chemistry. 53: 2204-14. PMID 20158204 DOI: 10.1021/Jm9017465  0.359
2010 Carroll FI, Ma W, Deng L, Navarro HA, Damaj MI, Martin BR. Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 3'-(substituted phenyl)epibatidine analogues. Nicotinic partial agonists. Journal of Natural Products. 73: 306-12. PMID 20038125 DOI: 10.1021/Np9006124  0.611
2010 Cheng Y, Dukat M, Dowd M, Fiedler W, Martin B, Damaj MI, Glennon RA. ChemInform Abstract: Synthesis and Binding of 6,7,8,9-Tetrahydro-5H-pyrido[3,4-d]azepine and Related Ring-Opened Analogues at Central Nicotinic Receptors. Cheminform. 30: no-no. DOI: 10.1002/CHIN.199930171  0.34
2009 Jackson KJ, McIntosh JM, Brunzell DH, Sanjakdar SS, Damaj MI. The role of alpha6-containing nicotinic acetylcholine receptors in nicotine reward and withdrawal. The Journal of Pharmacology and Experimental Therapeutics. 331: 547-54. PMID 19644040 DOI: 10.1124/Jpet.109.155457  0.816
2009 Jackson KJ, Walters CL, Miles MF, Martin BR, Damaj MI. Characterization of pharmacological and behavioral differences to nicotine in C57Bl/6 and DBA/2 mice. Neuropharmacology. 57: 347-55. PMID 19619563 DOI: 10.1016/J.Neuropharm.2009.07.020  0.82
2009 Jackson KJ, Walters CL, Damaj MI. Beta 2 subunit-containing nicotinic receptors mediate acute nicotine-induced activation of calcium/calmodulin-dependent protein kinase II-dependent pathways in vivo. The Journal of Pharmacology and Experimental Therapeutics. 330: 541-9. PMID 19435931 DOI: 10.1124/Jpet.109.153171  0.816
2009 Jackson KJ, Kota DH, Martin BR, Damaj MI. The role of various nicotinic receptor subunits and factors influencing nicotine conditioned place aversion. Neuropharmacology. 56: 970-4. PMID 19371584 DOI: 10.1016/J.Neuropharm.2009.01.023  0.854
2009 Jackson KJ, Damaj MI. L-type calcium channels and calcium/calmodulin-dependent kinase II differentially mediate behaviors associated with nicotine withdrawal in mice. The Journal of Pharmacology and Experimental Therapeutics. 330: 152-61. PMID 19336664 DOI: 10.1124/Jpet.109.151530  0.783
2008 Abdrakhmanova GR, Carroll FI, Damaj MI, Martin BR. 3'-Fluoro substitution in the pyridine ring of epibatidine improves selectivity and efficacy for alpha4beta2 versus alpha3beta4 nAChRs. Neuropharmacology. 55: 1287-92. PMID 18775444 DOI: 10.1016/j.neuropharm.2008.08.007  0.364
2008 Merritt LL, Martin BR, Walters C, Lichtman AH, Damaj MI. The endogenous cannabinoid system modulates nicotine reward and dependence. The Journal of Pharmacology and Experimental Therapeutics. 326: 483-92. PMID 18451315 DOI: 10.1124/Jpet.108.138321  0.687
2008 Kota D, Martin BR, Damaj MI. Age-dependent differences in nicotine reward and withdrawal in female mice. Psychopharmacology. 198: 201-10. PMID 18338157 DOI: 10.1007/S00213-008-1117-8  0.855
2008 Jackson KJ, Martin BR, Changeux JP, Damaj MI. Differential role of nicotinic acetylcholine receptor subunits in physical and affective nicotine withdrawal signs. The Journal of Pharmacology and Experimental Therapeutics. 325: 302-12. PMID 18184829 DOI: 10.1124/Jpet.107.132977  0.832
2008 Ivy Carroll F, Yokota Y, Ma W, Lee JR, Brieaddy LE, Burgess JP, Navarro HA, Damaj MI, Martin BR. Synthesis, nicotinic acetylcholine receptor binding, and pharmacological properties of 3'-(substituted phenyl)deschloroepibatidine analogs. Bioorganic & Medicinal Chemistry. 16: 746-54. PMID 17964169 DOI: 10.1016/J.Bmc.2007.10.027  0.436
2007 Carroll FI, Robinson TP, Brieaddy LE, Atkinson RN, Mascarella SW, Damaj MI, Martin BR, Navarro HA. Synthesis and nicotinic acetylcholine receptor binding properties of bridged and fused ring analogues of epibatidine. Journal of Medicinal Chemistry. 50: 6383-91. PMID 17994682 DOI: 10.1021/Jm0704696  0.369
2007 Damaj MI. Behavioral modulation of neuronal calcium/calmodulin-dependent protein kinase II activity: differential effects on nicotine-induced spinal and supraspinal antinociception in mice. Biochemical Pharmacology. 74: 1247-52. PMID 17850767 DOI: 10.1016/J.Bcp.2007.07.008  0.498
2007 Hansen HH, Timmermann DB, Peters D, Walters C, Damaj MI, Mikkelsen JD. Alpha-7 nicotinic acetylcholine receptor agonists selectively activate limbic regions of the rat forebrain: An effect similar to antipsychotics Journal of Neuroscience Research. 85: 1810-1818. PMID 17455307 DOI: 10.1002/Jnr.21293  0.482
2007 Kota D, Martin BR, Robinson SE, Damaj MI. Nicotine dependence and reward differ between adolescent and adult male mice. The Journal of Pharmacology and Experimental Therapeutics. 322: 399-407. PMID 17446302 DOI: 10.1124/Jpet.107.121616  0.854
2007 Damaj MI, Fonck C, Marks MJ, Deshpande P, Labarca C, Lester HA, Collins AC, Martin BR. Genetic approaches identify differential roles for alpha4beta2* nicotinic receptors in acute models of antinociception in mice. The Journal of Pharmacology and Experimental Therapeutics. 321: 1161-9. PMID 17371806 DOI: 10.1124/jpet.106.112649  0.533
2007 Ivy Carroll F, Ma W, Navarro HA, Abraham P, Wolckenhauer SA, Damaj MI, Martin BR. Synthesis, nicotinic acetylcholine receptor binding, antinociceptive and seizure properties of methyllycaconitine analogs. Bioorganic & Medicinal Chemistry. 15: 678-85. PMID 17098430 DOI: 10.1016/J.Bmc.2006.10.061  0.346
2007 Damaj MI. Nicotinic regulation of calcium/calmodulin-dependent protein kinase II activation in the spinal cord. The Journal of Pharmacology and Experimental Therapeutics. 320: 244-9. PMID 17041007 DOI: 10.1124/jpet.106.111336  0.38
2007 Damaj MI, Siu EC, Sellers EM, Tyndale RF, Martin BR. Inhibition of nicotine metabolism by methoxysalen: Pharmacokinetic and pharmacological studies in mice. The Journal of Pharmacology and Experimental Therapeutics. 320: 250-7. PMID 17021260 DOI: 10.1124/Jpet.106.111237  0.577
2007 Matta SG, Balfour DJ, Benowitz NL, Boyd RT, Buccafusco JJ, Caggiula AR, Craig CR, Collins AC, Damaj MI, Donny EC, Gardiner PS, Grady SR, Heberlein U, Leonard SS, Levin ED, et al. Guidelines on nicotine dose selection for in vivo research. Psychopharmacology. 190: 269-319. PMID 16896961 DOI: 10.1007/S00213-006-0441-0  0.584
2006 Wright MJ, Vann RE, Gamage TF, Damaj MI, Wiley JL. Comparative effects of dextromethorphan and dextrorphan on nicotine discrimination in rats. Pharmacology, Biochemistry, and Behavior. 85: 507-13. PMID 17112574 DOI: 10.1016/J.Pbb.2006.09.020  0.61
2006 Damaj MI, Zheng J, Martin BR, Kuhar MJ. Intrathecal CART (55-102) attenuates hyperlagesia and allodynia in a mouse model of neuropathic but not inflammatory pain. Peptides. 27: 2019-23. PMID 16814901 DOI: 10.1016/J.Peptides.2005.09.019  0.311
2006 Carroll FI, Hu X, Navarro HA, Deschamps J, Abdrakhmanova GR, Damaj MI, Martin BR. Synthesis and pharmacological characterization of nicotinic acetylcholine receptor properties of (+)- and (-)-pyrido-[3,4-b]homotropanes. Journal of Medicinal Chemistry. 49: 3244-50. PMID 16722642 DOI: 10.1021/Jm060122N  0.542
2006 Abdrakhmanova GR, Damaj MI, Carroll FI, Martin BR. 2-Fluoro-3-(4-nitro-phenyl)deschloroepibatidine is a novel potent competitive antagonist of human neuronal alpha4beta2 nAChRs. Molecular Pharmacology. 69: 1945-52. PMID 16505153 DOI: 10.1124/Mol.105.021782  0.511
2006 Grabus SD, Martin BR, Brown SE, Damaj MI. Nicotine place preference in the mouse: influences of prior handling, dose and strain and attenuation by nicotinic receptor antagonists. Psychopharmacology. 184: 456-63. PMID 16463055 DOI: 10.1007/S00213-006-0305-7  0.675
2006 Walters CL, Brown S, Changeux JP, Martin B, Damaj MI. The beta2 but not alpha7 subunit of the nicotinic acetylcholine receptor is required for nicotine-conditioned place preference in mice. Psychopharmacology. 184: 339-44. PMID 16416156 DOI: 10.1007/S00213-005-0295-X  0.655
2005 Carroll FI, Brieaddy LE, Navarro HA, Damaj MI, Martin BR. Synthesis and pharmacological characterization of exo-2-(2'-chloro-5-pyridinyl)-7-(endo and exo)-aminobicyclo[2.2.1]heptanes as novel epibatidine analogues. Journal of Medicinal Chemistry. 48: 7491-5. PMID 16279810 DOI: 10.1021/Jm058243V  0.401
2005 Damaj MI, Wiley JL, Martin BR, Papke RL. In vivo characterization of a novel inhibitor of CNS nicotinic receptors. European Journal of Pharmacology. 521: 43-8. PMID 16181622 DOI: 10.1016/J.Ejphar.2005.06.056  0.584
2005 Damaj MI. Calcium-acting drugs modulate expression and development of chronic tolerance to nicotine-induced antinociception in mice. The Journal of Pharmacology and Experimental Therapeutics. 315: 959-64. PMID 16099928 DOI: 10.1124/jpet.105.092460  0.364
2005 Dukat M, Ramunno A, Banzi R, Damaj MI, Martin B, Glennon RA. 3-(2-Aminoethyl)pyridine analogs as α4β2 nicotinic cholinergic receptor ligands Bioorganic and Medicinal Chemistry Letters. 15: 4308-4312. PMID 16039854 DOI: 10.1016/J.Bmcl.2005.06.053  0.606
2005 Ramunno A, Dukat M, Lee M, Young R, El-Zahabi M, Damaj MI, Martin B, Glennon RA. 6-(2-Phenylethyl)nicotine: A novel nicotinic cholinergic receptor ligand Bioorganic and Medicinal Chemistry Letters. 15: 3237-3240. PMID 15925512 DOI: 10.1016/J.Bmcl.2005.04.072  0.628
2005 Carroll FI, Ma W, Yokota Y, Lee JR, Brieaddy LE, Navarro HA, Damaj MI, Martin BR. Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 3'-substituted deschloroepibatidine analogues. Novel nicotinic antagonists. Journal of Medicinal Chemistry. 48: 1221-8. PMID 15715488 DOI: 10.1021/jm040160b  0.35
2005 Grabus SD, Martin BR, Batman AM, Tyndale RF, Sellers E, Damaj MI. Nicotine physical dependence and tolerance in the mouse following chronic oral administration. Psychopharmacology. 178: 183-92. PMID 15365686 DOI: 10.1007/S00213-004-2007-3  0.664
2005 Damaj MI, Flood P, Ho KK, May EL, Martin BR. Effect of dextrometorphan and dextrorphan on nicotine and neuronal nicotinic receptors: in vitro and in vivo selectivity. The Journal of Pharmacology and Experimental Therapeutics. 312: 780-5. PMID 15356218 DOI: 10.1124/Jpet.104.075093  0.519
2004 Damaj MI, Hunter RG, Martin BR, Kuhar MJ. Intrathecal CART (55-102) enhances the spinal analgesic actions of morphine in mice. Brain Research. 1024: 146-9. PMID 15451376 DOI: 10.1016/J.Brainres.2004.07.058  0.347
2004 Damaj MI, Carroll FI, Eaton JB, Navarro HA, Blough BE, Mirza S, Lukas RJ, Martin BR. Enantioselective effects of hydroxy metabolites of bupropion on behavior and on function of monoamine transporters and nicotinic receptors. Molecular Pharmacology. 66: 675-82. PMID 15322260 DOI: 10.1124/Mol.104.001313  0.476
2004 Carroll FI, Ware R, Brieaddy LE, Navarro HA, Damaj MI, Martin BR. Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2'-fluoro-3'-(substituted phenyl)deschloroepibatidine analogues. Novel nicotinic antagonist. Journal of Medicinal Chemistry. 47: 4588-94. PMID 15317468 DOI: 10.1021/Jm040078G  0.443
2004 Dukat M, Taroua M, Dahdouh A, Siripurapu U, Damaj MI, Martin BR, Glennon RA. (+/-)8-Amino-5,6,7,8-tetrahydroisoquinolines as novel antinociceptive agents. Bioorganic & Medicinal Chemistry Letters. 14: 3651-4. PMID 15203136 DOI: 10.1016/J.Bmcl.2004.05.020  0.471
2004 Dogruer D, Lee M, Dukat M, Damaj MI, Martin BR, Glennon RA. 3-(4-Aminobutyn-1-yl)pyridines: binding at alpha 4 beta 2 nicotinic cholinergic receptors. Bioorganic & Medicinal Chemistry Letters. 14: 523-6. PMID 14698195 DOI: 10.1016/J.Bmcl.2003.10.033  0.398
2003 Lester HA, Fonck C, Tapper AR, McKinney S, Damaj MI, Balogh S, Owens J, Wehner JM, Collins AC, Labarca C. Hypersensitive knockin mouse strains identify receptors and pathways for nicotine action. Current Opinion in Drug Discovery & Development. 6: 633-9. PMID 14579512  0.517
2003 Damaj MI, Kao W, Martin BR. Characterization of spontaneous and precipitated nicotine withdrawal in the mouse. The Journal of Pharmacology and Experimental Therapeutics. 307: 526-34. PMID 12970387 DOI: 10.1124/jpet.103.054908  0.596
2003 Damaj MI. In vivo enantioselectivity of epibatidine interaction with calcium-modulating drugs. Brain Research. 982: 293-296. PMID 12915265 DOI: 10.1016/S0006-8993(03)03089-0  0.324
2003 Damaj MI, Martin BR, Kuhar MJ. Antinociceptive effects of supraspinal rat cart (55-102) peptide in mice. Brain Research. 983: 233-6. PMID 12914986 DOI: 10.1016/S0006-8993(03)03094-4  0.337
2003 Fonck C, Nashmi R, Deshpande P, Damaj MI, Marks MJ, Riedel A, Schwarz J, Collins AC, Labarca C, Lester HA. Increased sensitivity to agonist-induced seizures, straub tail, and hippocampal theta rhythm in knock-in mice carrying hypersensitive alpha 4 nicotinic receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 2582-90. PMID 12684443  0.377
2003 Ferretti G, Dukat M, Giannella M, Piergentili A, Pigini M, Quaglia W, Damaj MI, Martin BR, Glennon RA. Binding of nicotine and homoazanicotine analogues at neuronal nicotinic acetylcholinergic (nACh) receptors. Bioorganic & Medicinal Chemistry Letters. 13: 733-5. PMID 12639569 DOI: 10.1016/S0960-894X(02)01031-4  0.437
2003 Fonck C, Nashmi R, Deshpande P, Damaj MI, Marks MJ, Riedel A, Schwarz J, Collins AC, Labarca C, Lester HA. Increased Sensitivity to Agonist-Induced Seizures, Straub Tail, and Hippocampal Theta Rhythm in Knock-In Mice Carrying Hypersensitive α4 Nicotinic Receptors The Journal of Neuroscience. 23: 2582-2590. DOI: 10.1523/Jneurosci.23-07-02582.2003  0.536
2003 Dukat M, El-Zahabi M, Ferretti G, Damaj MI, Martin BR, Young R, Glennon RA. (-)6-n-Propylnicotine Antagonizes the Antinociceptive Effects of (-)Nicotine. Cheminform. 34. DOI: 10.1002/CHIN.200307159  0.465
2002 Carroll FI, Lee JR, Navarro HA, Ma W, Brieaddy LE, Abraham P, Damaj MI, Martin BR. Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2',3'-disubstituted 5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes: epibatidine analogues. Journal of Medicinal Chemistry. 45: 4755-61. PMID 12361403 DOI: 10.1021/Jm0202268  0.412
2002 Ferretti G, Dukat M, Giannella M, Piergentili A, Pigini M, Quaglia W, Damaj MI, Martin BR, Glennon RA. Homoazanicotine: a structure-affinity study for nicotinic acetylcholine (nACh) receptor binding. Journal of Medicinal Chemistry. 45: 4724-31. PMID 12361399 DOI: 10.1021/Jm020188S  0.358
2002 Dukat M, El-Zahabi M, Ferretti G, Damaj MI, Martin BR, Young R, Glennon RA. (-)6-n-Propylnicotine antagonizes the antinociceptive effects of (-)nicotine. Bioorganic & Medicinal Chemistry Letters. 12: 3005-7. PMID 12270194 DOI: 10.1016/S0960-894X(02)00614-5  0.616
2002 Lee M, Dukat M, Liao L, Flammia D, Damaj MI, Martin B, Glennon RA. A comparison of the binding of three series of nicotinic ligands. Bioorganic & Medicinal Chemistry Letters. 12: 1989-92. PMID 12113825 DOI: 10.1016/S0960-894X(02)00298-6  0.433
2002 Wiley JL, Lavecchia KL, Martin BR, Damaj MI. Nicotine-like discriminative stimulus effects of bupropion in rats. Experimental and Clinical Psychopharmacology. 10: 129-35. PMID 12022798 DOI: 10.1037//1064-1297.10.2.129  0.525
2002 Wiley JL, LaVecchia KL, Martin BR, Damaj MI. Nicotine-like discriminative stimulus effects of bupropion in rats. Experimental and Clinical Psychopharmacology. 10: 129-135. DOI: 10.1037/1064-1297.10.2.129  0.38
2001 Carroll FI, Lee JR, Navarro HA, Brieaddy LE, Abraham P, Damaj MI, Martin BR. Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2'-substituted-3'-phenyl-5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes. Novel nicotinic antagonist. Journal of Medicinal Chemistry. 44: 4039-41. PMID 11708907 DOI: 10.1021/Jm015561V  0.447
2001 Salmon AM, Damaj MI, Marubio LM, Epping-Jordan MP, Merlo-Pich E, Changeux JP. Altered neuroadaptation in opiate dependence and neurogenic inflammatory nociception in alpha CGRP-deficient mice. Nature Neuroscience. 4: 357-8. PMID 11276224 DOI: 10.1038/86001  0.353
2001 Damaj MI. Influence of gender and sex hormones on nicotine acute pharmacological effects in mice. The Journal of Pharmacology and Experimental Therapeutics. 296: 132-40. PMID 11123373  0.587
2001 Damaj MI. The involvement of spinal Ca(2+)/calmodulin-protein kinase II in nicotine-induced antinociception in mice. European Journal of Pharmacology. 404: 103-10. PMID 10980268 DOI: 10.1016/S0014-2999(00)00579-3  0.505
2001 Ferretti G, Dukat M, Giannella M, Piergentili A, Pigini M, Quaglia W, Damaj MI, Martin BR, Glennon RA. ChemInform Abstract: Chain-Lengthened and Imidazoline Analogues of Nicotine. Cheminform. 32: no-no. DOI: 10.1002/CHIN.200114217  0.443
2000 Ferretti G, Dukat M, Giannella M, Piergentili A, Pigini M, Quaglia W, Damaj MI, Martin BR, Glennon RA. Chain-lengthened and imidazoline analogues of nicotine. Bioorganic & Medicinal Chemistry Letters. 10: 2665-8. PMID 11128647 DOI: 10.1016/S0960-894X(00)00541-2  0.547
2000 Damaj MI, Meyer EM, Martin BR. The antinociceptive effects of alpha7 nicotinic agonists in an acute pain model. Neuropharmacology. 39: 2785-91. PMID 11044748 DOI: 10.1016/S0028-3908(00)00139-8  0.532
2000 Slemmer JE, Martin BR, Damaj MI. Bupropion is a nicotinic antagonist. The Journal of Pharmacology and Experimental Therapeutics. 295: 321-7. PMID 10991997  0.466
1999 Damaj MI, Glassco W, Dukat M, Martin BR. Pharmacological characterization of nicotine-induced seizures in mice. The Journal of Pharmacology and Experimental Therapeutics. 291: 1284-91. PMID 10565853  0.488
1999 Damaj MI, Glassco W, Aceto MD, Martin BR. Antinociceptive and pharmacological effects of metanicotine, a selective nicotinic agonist. The Journal of Pharmacology and Experimental Therapeutics. 291: 390-8. PMID 10490929  0.589
1999 Flammia D, Dukat M, Damaj MI, Martin B, Glennon RA. Lobeline: Structure-affinity investigation of nicotinic acetylcholinergic receptor binding Journal of Medicinal Chemistry. 42: 3726-3731. PMID 10479304 DOI: 10.1021/Jm990286M  0.474
1999 Damaj MI, Slemmer JE, Carroll FI, Martin BR. Pharmacological characterization of nicotine's interaction with cocaine and cocaine analogs. The Journal of Pharmacology and Experimental Therapeutics. 289: 1229-36. PMID 10336510  0.45
1999 Marubio LM, del Mar Arroyo-Jimenez M, Cordero-Erausquin M, Léna C, Le Novère N, de Kerchove d'Exaerde A, Huchet M, Damaj MI, Changeux JP. Reduced antinociception in mice lacking neuronal nicotinic receptor subunits. Nature. 398: 805-10. PMID 10235262 DOI: 10.1038/19756  0.547
1999 Dukat M, Dowd M, Damaj MI, Martin B, El-Zahabi MA, Glennon RA. Synthesis, receptor binding and QSAR studies on 6-substituted nicotine derivatives as cholinergic ligands European Journal of Medicinal Chemistry. 34: 31-40. DOI: 10.1016/S0223-5234(99)80038-5  0.522
1998 Damaj MI, Fei-Yin M, Dukat M, Glassco W, Glennon RA, Martin BR. Antinociceptive responses to nicotinic acetylcholine receptor ligands after systemic and intrathecal administration in mice. The Journal of Pharmacology and Experimental Therapeutics. 284: 1058-65. PMID 9495867  0.522
1997 Damaj MI, Glassco W, Marks MJ, Slobe B, James JR, May EL, Rosecrans JA, Collins AC, Martin BR. Pharmacological investigation of (+)- and (-)-cis-2,3,3a,4,5,9b-hexahydro-1-methyl-1H-pyrrolo-[3,2-h]isoq uinoline, a bridged-nicotine analog. The Journal of Pharmacology and Experimental Therapeutics. 282: 1425-34. PMID 9316856  0.579
1997 Damaj MI, Patrick GS, Creasy KR, Martin BR. Pharmacology of lobeline, a nicotinic receptor ligand. The Journal of Pharmacology and Experimental Therapeutics. 282: 410-9. PMID 9223582  0.496
1997 Damaj MI. Altered behavioral sensitivity of Ca(2+)-modulating drugs after chronic nicotine administration in mice. European Journal of Pharmacology. 322: 129-35. PMID 9098679 DOI: 10.1016/S0014-2999(97)00007-1  0.572
1996 Damaj MI, Martin BR. Tolerance to the antinociceptive effect of epibatidine after acute and chronic administration in mice. European Journal of Pharmacology. 300: 51-7. PMID 8741164 DOI: 10.1016/0014-2999(95)00834-9  0.575
1996 Damaj MI, Welch SP, Martin BR. Characterization and modulation of acute tolerance to nicotine in mice. The Journal of Pharmacology and Experimental Therapeutics. 277: 454-61. PMID 8613954  0.505
1995 Damaj MI, Creasy KR, Welch SP, Rosecrans JA, Aceto MD, Martin BR. Comparative pharmacology of nicotine and ABT-418, a new nicotinic agonist. Psychopharmacology. 120: 483-90. PMID 8539331 DOI: 10.1007/Bf02245822  0.493
1995 Damaj MI, Welch SP, Martin BR. In vivo pharmacological effects of dihydro-β-erythroidine, a nicotinic antagonist, in mice Psychopharmacology. 117: 67-73. PMID 7724704 DOI: 10.1007/Bf02245100  0.508
1994 Damaj MI, Glennon RA, Martin BR. Involvement of the serotonergic system in the hypoactive and antinociceptive effects of nicotine in mice. Brain Research Bulletin. 33: 199-203. PMID 8275340 DOI: 10.1016/0361-9230(94)90252-6  0.548
1994 Damaj MI, Welch SP, Martin BR. Nicotine-induced antinociception in mice: Role of G-proteins and adenylate cyclase Pharmacology, Biochemistry and Behavior. 48: 37-42. PMID 8029303 DOI: 10.1016/0091-3057(94)90494-4  0.503
1994 Damaj MI, Creasy KR, Grove AD, Rosecrans JA, Martin BR. Pharmacological effects of epibatidine optical enantiomers. Brain Research. 664: 34-40. PMID 7895043 DOI: 10.1016/0006-8993(94)91950-X  0.385
1993 Damaj MI, Martin BR. Is the dopaminergic system involved in the central effects of nicotine in mice Psychopharmacology. 111: 106-108. PMID 7870924 DOI: 10.1007/Bf02257415  0.51
1993 Damaj MI, Welch SP, Martin BR. Involvement of calcium and L-type channels in nicotine-induced antinociception. The Journal of Pharmacology and Experimental Therapeutics. 266: 1330-8. PMID 7690401  0.414
1993 Damaj MI, Martin BR. Calcium agonists and antagonists of the dihydropyridine type: effect on nicotine-induced antinociception and hypomotility. Drug and Alcohol Dependence. 32: 73-9. PMID 7683598 DOI: 10.1016/0376-8716(93)90024-K  0.428
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