Lyle D. Isaacs, Ph.D. - Publications

Affiliations: 
1998- Chemistry and Biochemistry University of Maryland, College Park, College Park, MD 
Area:
supramolecular and synthetic chemistry
Website:
http://www.chem.umd.edu/lyle-isaacs/

130 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Warmerdam Z, Kamba BE, Le MH, Schrader T, Isaacs L, Bayer P, Hof F. Binding Methylarginines and Methyllysines as Free Amino Acids: A Comparative Study of Multiple Host Classes. Chembiochem : a European Journal of Chemical Biology. 23: e202100502. PMID 34758178 DOI: 10.1002/cbic.202100502  0.605
2020 Ndendjio SZ, Liu W, Yvanez N, Meng Z, Zavalij PY, Isaacs LD. Triptycene walled glycoluril trimer: synthesis and recognition properties New Journal of Chemistry. 44: 338-345. PMID 33867799 DOI: 10.1039/C9Nj05336K  0.379
2020 Brady KG, Gilberg L, Sigwalt D, Bistany-Riebman J, Murkli S, Klemm J, Kulhánek P, Šindelář V, Isaacs L. Conformationally Mobile Acyclic Cucurbit[n]uril-Type Receptors Derived from an S-shaped Methylene Bridged Glycoluril Pentamer. Supramolecular Chemistry. 32: 479-494. PMID 33731981 DOI: 10.1080/10610278.2020.1795173  0.337
2020 Lu X, Zebaze Ndendjio SA, Zavalij PY, Isaacs L. Acyclic Cucurbit[]uril-Type Receptors: Optimization of Electrostatic Interactions for Dicationic Guests. Organic Letters. PMID 32520574 DOI: 10.1021/Acs.Orglett.0C01637  0.316
2019 Pandey S, Kankanamalage DVDW, Zhou X, Hu C, Isaacs L, Jayawickramarajah J, Mao H. Chaperone Assisted Host-Guest Interactions Revealed by Single-Molecule Force Spectroscopy. Journal of the American Chemical Society. PMID 31679339 DOI: 10.1021/Jacs.9B09019  0.355
2019 Liu W, Ai H, Meng Z, Isaacs L, Xu Z, Xue M, Yan Q. Interactions between acyclic CB[n]-type receptors and nitrated explosive materials. Chemical Communications (Cambridge, England). PMID 31429448 DOI: 10.1039/C9Cc05117A  0.325
2019 Xue W, Zavalij PY, Isaacs L. Triazole functionalized acyclic cucurbit[n]uril-type receptors: host·guest recognition properties Organic and Biomolecular Chemistry. 17: 5561-5569. PMID 31112196 DOI: 10.1039/C9Ob00906J  0.37
2019 Murkli S, McNeill JN, Isaacs L. Cucurbit[8]uril•guest complexes: blinded dataset for the SAMPL6 challenge Supramolecular Chemistry. 31: 150-158. DOI: 10.1080/10610278.2018.1516885  0.355
2018 Samanta SK, Moncelet D, Vinciguerra B, Briken V, Isaacs L. Metal Organic Polyhedra: A Click-and-Clack Approach Toward Targeted Delivery. Helvetica Chimica Acta. 101. PMID 31231137 DOI: 10.1002/Hlca.201800057  0.322
2018 Rizzi A, Murkli S, McNeill JN, Yao W, Sullivan M, Gilson MK, Chiu MW, Isaacs L, Gibb BC, Mobley DL, Chodera JD. Overview of the SAMPL6 host-guest binding affinity prediction challenge. Journal of Computer-Aided Molecular Design. PMID 30415285 DOI: 10.1007/S10822-018-0170-6  0.322
2018 Liu W, Lu X, Meng Z, Isaacs L. A glycoluril dimer-triptycene hybrid receptor: synthesis and molecular recognition properties. Organic & Biomolecular Chemistry. PMID 30155536 DOI: 10.1039/C8Ob01575A  0.366
2018 Liu W, Lu X, Xue W, Samanta SK, Zavalij PY, Meng Z, Isaacs L. Hybrid molecular container based on glycoluril and triptycene: synthesis, binding properties, and triggered release. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 30044903 DOI: 10.1002/Chem.201802981  0.389
2018 Lu X, Samanta SK, Zavalij PY, Isaacs L. Blurring the Lines Between Host and Guest: A Chimeric Receptor Derived from Cucurbituril and Triptycene. Angewandte Chemie (International Ed. in English). PMID 29749674 DOI: 10.1002/Anie.201803132  0.36
2018 Liu W, Lu X, Xue W, Samanta SK, Zavalij PY, Meng Z, Isaacs L. Front Cover: Hybrid Molecular Container Based on Glycoluril and Triptycene: Synthesis, Binding Properties, and Triggered Release (Chem. Eur. J. 53/2018) Chemistry – a European Journal. 24: 13983-13983. DOI: 10.1002/Chem.201804178  0.303
2017 Li Y, Dong Y, Miao X, Ren Y, Zhang B, Wang P, Yu Y, Li B, Isaacs L, Cao L. Shape-Controllable and Fluorescent Supramolecular Organic Frameworks Through Aqueous Host-Guest Complexation. Angewandte Chemie (International Ed. in English). PMID 29193530 DOI: 10.1002/Anie.201710553  0.309
2017 Zhou X, Su X, Pathak P, Vik R, Vinciguerra B, Isaacs L, Jayawickramarajah J. Host-Guest Tethered DNA Transducer: ATP Fueled Release of a Protein Inhibitor from Cucurbit[7]uril. Journal of the American Chemical Society. PMID 28882044 DOI: 10.1021/Jacs.7B07977  0.343
2017 Samanta S, Quigley J, Vinciguerra B, Briken V, Isaacs L. Cucurbit[7]uril Enables Multistimuli Responsive Release from the Self-Assembled Hydrophobic Phase of a Metal Organic Polyhedron. Journal of the American Chemical Society. PMID 28621947 DOI: 10.1021/Jacs.7B05154  0.325
2017 Ganapati S, Grabitz SD, Murkli S, Scheffenbichler F, Rudolph MI, Zavalij PY, Eikermann M, Isaacs L. Molecular Containers Bind Drugs of Abuse in Vitro and Reverse the Hyperlocomotive Effect of Methamphetamine in Rats. Chembiochem : a European Journal of Chemical Biology. 18: 1583-1588. PMID 28586110 DOI: 10.1002/Cbic.201700289  0.322
2017 Samanta SK, Brady KG, Isaacs L. Self-assembly of cucurbit[7]uril based triangular [4]molecular necklaces and their fluorescence properties. Chemical Communications (Cambridge, England). PMID 28210729 DOI: 10.1039/C6Cc10328F  0.366
2017 Liu W, Samanta SK, Smith BD, Isaacs L. Synthetic mimics of biotin/(strept)avidin. Chemical Society Reviews. PMID 28191579 DOI: 10.1039/C7Cs00011A  0.326
2017 Sigwalt D, Šekutor M, Cao L, Zavalij PY, Hostaš J, Ajani H, Hobza P, Mlinarić-Majerski K, Glaser R, Isaacs L. Unraveling the Structure-Affinity Relationship Between Cucurbit[n]urils (n = 7, 8) and Cationic Diamondoids. Journal of the American Chemical Society. PMID 28182422 DOI: 10.1021/Jacs.7B00056  0.398
2016 Bockus AT, Smith LC, Grice AG, Ali OA, Young CC, Mobley W, Leek A, Roberts JL, Vinciguerra B, Isaacs L, Urbach AR. Cucurbit[7]uril-Tetramethylrhodamine Conjugate for Direct Sensing and Cellular Imaging. Journal of the American Chemical Society. 138: 16549-16552. PMID 27998093 DOI: 10.1021/Jacs.6B11140  0.683
2016 Webber MJ, Appel EA, Vinciguerra B, Cortinas AB, Thapa LS, Jhunjhunwala S, Isaacs L, Langer R, Anderson DG. Supramolecular PEGylation of biopharmaceuticals. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911829 DOI: 10.1073/Pnas.1616639113  0.31
2016 Gong W, Yang X, Zavalij PY, Isaacs L, Zhao Z, Liu S. From Packed "Sandwich" to "Russian Doll": Assembly by Charge-Transfer Interactions in Cucurbit[10]uril. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27862408 DOI: 10.1002/Chem.201604149  0.378
2016 Samanta SK, Moncelet D, Briken V, Isaacs L. Metal Organic Polyhedron Capped with Cucurbit[8]uril Delivers Doxorubicin to Cancer Cells. Journal of the American Chemical Society. PMID 27723965 DOI: 10.1021/Jacs.6B09504  0.363
2016 Hostaš J, Sigwalt D, Šekutor M, Ajani H, Dubecký M, Řezáč J, Zavalij PY, Cao L, Wohlschlager C, Mlinarić-Majerski K, Isaacs L, Glaser R, Hobza P. A Nexus between Theory and Experiment: Non-Empirical Quantum Mechanical Computational Methodology Applied to Cucurbit[n]uril⋅Guest Binding Interactions. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27723181 DOI: 10.1002/Chem.201601833  0.381
2016 She N, Moncelet D, Gilberg L, Lu X, Sindelar V, Briken V, Isaacs L. Glycoluril-Derived Molecular Clips are Potent and Selective Receptors for Cationic Dyes in Water. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27492252 DOI: 10.1002/Chem.201601796  0.401
2016 Li W, Bockus AT, Vinciguerra B, Isaacs L, Urbach AR. Predictive recognition of native proteins by cucurbit[7]uril in a complex mixture. Chemical Communications (Cambridge, England). PMID 27311878 DOI: 10.1039/C6Cc03193E  0.679
2016 Lu X, Isaacs L. Uptake of Hydrocarbons in Aqueous Solution by Encapsulation in Acyclic Cucurbit[n]uril-Type Molecular Containers. Angewandte Chemie (International Ed. in English). PMID 27169688 DOI: 10.1002/Anie.201602671  0.366
2016 Carroy G, Lemaur V, De Winter J, Isaacs L, De Pauw E, Cornil J, Gerbaux P. Energy-resolved collision-induced dissociation of non-covalent ions: charge- and guest-dependence of decomplexation reaction efficiencies. Physical Chemistry Chemical Physics : Pccp. PMID 27086657 DOI: 10.1039/C6Cp01026A  0.302
2016 Sigwalt D, Moncelet D, Falcinelli S, Mandadapu V, Zavalij PY, Day A, Briken V, Isaacs L. Acyclic Cucurbit[n]uril-Type Molecular Containers: Influence of Linker Length on Their Function as Solubilizing Agents. Chemmedchem. PMID 26990780 DOI: 10.1002/Cmdc.201600090  0.308
2016 Škalamera D, Cao L, Isaacs L, Glaser R, Mlinarić-Majerski K. Steric hindrance to the syntheses and stabilities of 1,5- and 2,6-naphthalene N-permethylated diammonium salts Tetrahedron. 72: 1541-1546. DOI: 10.1016/J.Tet.2016.02.002  0.35
2015 Zhang M, Sigwalt D, Isaacs L. Differentially functionalized acyclic cucurbiturils: synthesis, self-assembly and CB[6]-induced allosteric guest binding. Chemical Communications (Cambridge, England). 51: 14620-3. PMID 26288859 DOI: 10.1039/C5Cc05803A  0.394
2015 Lu X, Isaacs L. Synthesis and Recognition Properties of Enantiomerically Pure Acyclic Cucurbit[n]uril-Type Molecular Containers. Organic Letters. 17: 4038-41. PMID 26251172 DOI: 10.1021/Acs.Orglett.5B01948  0.404
2015 Cao L, Škalamera Đ, Zavalij PY, Hostaš J, Hobza P, Mlinarić-Majerski K, Glaser R, Isaacs L. Influence of hydrophobic residues on the binding of CB[7] toward diammonium ions of common ammonium···ammonium distance. Organic & Biomolecular Chemistry. 13: 6249-54. PMID 25962667 DOI: 10.1039/C5Ob00784D  0.334
2015 Robinson EL, Zavalij PY, Isaacs L. Synthesis of a Disulfonated Derivative of Cucurbit[7]uril and Investigations of its Ability to Solubilize Insoluble Drugs. Supramolecular Chemistry. 27: 288-297. PMID 25937787 DOI: 10.1080/10610278.2014.940952  0.344
2015 Gilberg L, Zhang B, Zavalij PY, Sindelar V, Isaacs L. Acyclic cucurbit[n]uril-type molecular containers: influence of glycoluril oligomer length on their function as solubilizing agents. Organic & Biomolecular Chemistry. 13: 4041-50. PMID 25731639 DOI: 10.1039/C5Ob00184F  0.392
2015 Yu Y, Li J, Zhang M, Cao L, Isaacs L. Hydrophobic monofunctionalized cucurbit[7]uril undergoes self-inclusion complexation and forms vesicle-type assemblies. Chemical Communications (Cambridge, England). 51: 3762-5. PMID 25647163 DOI: 10.1039/C5Cc00236B  0.353
2014 Zhang M, Cao L, Isaacs L. Cucurbit[6]uril-cucurbit[7]uril heterodimer promotes controlled self-assembly of supramolecular networks and supramolecular micelles by self-sorting of amphiphilic guests. Chemical Communications (Cambridge, England). 50: 14756-9. PMID 25318021 DOI: 10.1039/C4Cc07268E  0.335
2014 Zhang B, Zavalij PY, Isaacs L. Acyclic CB[n]-type molecular containers: effect of solubilizing group on their function as solubilizing excipients Organic and Biomolecular Chemistry. 12: 2413-2422. PMID 24595500 DOI: 10.1039/C3Ob42603C  0.372
2014 Cao L, Śekutor M, Zavalij PY, Mlinarić-Majerski K, Glaser R, Isaacs L. Cucurbit[7]uril⋅guest pair with an attomolar dissociation constant. Angewandte Chemie (International Ed. in English). 53: 988-93. PMID 24382654 DOI: 10.1002/Anie.201309635  0.358
2014 Hoffman U, Grosse-Sundrup M, Eikermann-Haerter K, Zaremba S, Ayata C, Zhang B, Ma D, Isaacs L, Eikermann M. Calabadion: A New Agent to Reverse the Effects of Benzylisoquinoline and Steroidal Neuromuscular-Blocking Agents Survey of Anesthesiology. 58: 47. DOI: 10.1097/Sa.0000000000000028  0.406
2014 Cao L, Isaacs L. Absolute and relative binding affinity of cucurbit[7]uril towards a series of cationic guests Supramolecular Chemistry. 26: 251-258. DOI: 10.1080/10610278.2013.852674  0.349
2014 Wittenberg JB, Isaacs L. Cucurbit[6]uril dimer induces supramolecular polymerisation of a cationic polyethylene glycol derivative Supramolecular Chemistry. 26: 157-167. DOI: 10.1080/10610278.2013.842642  0.634
2014 Šekutor M, Molčanov K, Cao L, Isaacs L, Glaser R, Mlinaric̈-Majerski K. Design, synthesis, and X-ray structural analyses of diamantane diammonium salts: Guests for cucurbit[n]uril (CB[n]) hosts European Journal of Organic Chemistry. 2014: 2533-2542. DOI: 10.1002/Ejoc.201301844  0.392
2013 Lemaur V, Carroy G, Poussigue F, Chirot F, De Winter J, Isaacs L, Dugourd P, Cornil J, Gerbaux P. Homotropic Allosterism: In-Depth Structural Analysis of the Gas-Phase Noncovalent Complexes Associating a Double-Cavity Cucurbit[n]uril-Type Host and Size-Selected Protonated Amino Compounds. Chempluschem. 78: 959-969. PMID 31986725 DOI: 10.1002/Cplu.201300208  0.335
2013 Hoffmann U, Grosse-Sundrup M, Eikermann-Haerter K, Zaremba S, Ayata C, Zhang B, Ma D, Isaacs L, Eikermann M. Calabadion: A new agent to reverse the effects of benzylisoquinoline and steroidal neuromuscular-blocking agents. Anesthesiology. 119: 317-25. PMID 23549405 DOI: 10.1097/Aln.0B013E3182910213  0.419
2013 Wittenberg JB, Zavalij PY, Isaacs L. Supramolecular ladders from dimeric cucurbit[6]uril. Angewandte Chemie (International Ed. in English). 52: 3690-4. PMID 23417996 DOI: 10.1002/Anie.201300404  0.611
2013 Ghosh S, Mukhopadhyay P, Isaacs L. Deconvolution of a multi-component interaction network using systems chemistry Journal of Systems Chemistry. 1. DOI: 10.1186/1759-2208-1-6  0.704
2013 Hettiarachchi G, Ma D, Nguyen D, Isaacs L, Briken V. Abstract 4347: Toxicology and drug delivery by novel Cucurbit[n]uril-type molecular containers. Cancer Research. 73: 4347-4347. DOI: 10.1158/1538-7445.Am2013-4347  0.5
2013 Lemaur V, Carroy G, Poussigue F, Chirot F, De Winter J, Isaacs L, Dugourd P, Cornil J, Gerbaux P. Back Cover: Homotropic Allosterism: In-Depth Structural Analysis of the Gas-Phase Noncovalent Complexes Associating a Double-Cavity Cucurbit[n ]uril-Type Host and Size-Selected Protonated Amino Compounds (ChemPlusChem 9/2013) Chempluschem. 78: 1208-1208. DOI: 10.1002/Cplu.201300279  0.322
2012 Ma D, Zhang B, Hoffmann U, Sundrup MG, Eikermann M, Isaacs L. Acyclic cucurbit[n]uril-type molecular containers bind neuromuscular blocking agents in vitro and reverse neuromuscular block in vivo. Angewandte Chemie (International Ed. in English). 51: 11358-62. PMID 23047893 DOI: 10.1002/Anie.201206031  0.505
2012 Vinciguerra B, Cao L, Cannon JR, Zavalij PY, Fenselau C, Isaacs L. Synthesis and self-assembly processes of monofunctionalized cucurbit[7]uril. Journal of the American Chemical Society. 134: 13133-40. PMID 22799491 DOI: 10.1021/Ja3058502  0.396
2012 Chernikova E, Berdnikova D, Fedorov Y, Fedorova O, Peregudov A, Isaacs L. Self-assembly of a ternary architecture driven by cooperative Hg2+ ion binding between cucurbit[7]uril and crown ether macrocyclic hosts Chemical Communications. 48: 7256-7258. PMID 22710743 DOI: 10.1039/C2Cc33243D  0.363
2012 Cao L, Isaacs L. Daisy chain assembly formed from a cucurbit[6]uril derivative. Organic Letters. 14: 3072-5. PMID 22650758 DOI: 10.1021/Ol3011425  0.382
2012 Ma D, Hettiarachchi G, Nguyen D, Zhang B, Wittenberg JB, Zavalij PY, Briken V, Isaacs L. Acyclic cucurbit[n]uril molecular containers enhance the solubility and bioactivity of poorly soluble pharmaceuticals. Nature Chemistry. 4: 503-10. PMID 22614387 DOI: 10.1038/Nchem.1326  0.65
2012 Shen C, Ma D, Meany B, Isaacs L, Wang Y. Acyclic cucurbit[n]uril molecular containers selectively solubilize single-walled carbon nanotubes in water. Journal of the American Chemical Society. 134: 7254-7. PMID 22512431 DOI: 10.1021/Ja301462E  0.488
2012 Muddana HS, Varnado CD, Bielawski CW, Urbach AR, Isaacs L, Geballe MT, Gilson MK. Blind prediction of host-guest binding affinities: a new SAMPL3 challenge. Journal of Computer-Aided Molecular Design. 26: 475-87. PMID 22366955 DOI: 10.1007/S10822-012-9554-1  0.671
2012 Ma D, Glassenberg R, Ghosh S, Zavalij PY, Isaacs L. Acyclic cucurbituril congener binds to local anaesthetics Supramolecular Chemistry. 24: 325-332. DOI: 10.1080/10610278.2012.658394  0.647
2011 Lucas D, Minami T, Iannuzzi G, Cao L, Wittenberg JB, Anzenbacher P, Isaacs L. Templated synthesis of glycoluril hexamer and monofunctionalized cucurbit[6]uril derivatives. Journal of the American Chemical Society. 133: 17966-76. PMID 21970313 DOI: 10.1021/Ja208229D  0.707
2011 Wittenberg JB, Costales MG, Zavalij PY, Isaacs L. A clipped [3]rotaxane derived from bis-nor-seco-cucurbit[10]uril. Chemical Communications (Cambridge, England). 47: 9420-2. PMID 21776502 DOI: 10.1039/C1Cc13358F  0.62
2011 Lucas D, Isaacs L. Recognition properties of acyclic glycoluril oligomers. Organic Letters. 13: 4112-5. PMID 21739945 DOI: 10.1021/Ol201636Q  0.612
2011 Hettiarachchi G, Ma D, Nguyen D, Isaacs L, Briken V. Abstract 4429: Toxicology and drug delivery by novel cucurbit[n]uril-type nanocontainers Cancer Research. 71: 4429-4429. DOI: 10.1158/1538-7445.Am2011-4429  0.484
2010 Ma D, Zavalij PY, Isaacs L. Acyclic cucurbit[n]uril congeners are high affinity hosts. The Journal of Organic Chemistry. 75: 4786-95. PMID 20540586 DOI: 10.1021/Jo100760G  0.559
2010 Cao LP, Meng XG, Ding JY, Chen YF, Gao M, Wu YD, Li YT, Wu AX, Isaacs L. Nanotubular non-covalent macrocycle within non-covalent macrocycle assembly: (MeOH)(12) encapsulated in a molecular clip cyclododecamer. Chemical Communications (Cambridge, England). 46: 4508-10. PMID 20485785 DOI: 10.1039/C0Cc00677G  0.322
2010 Hettiarachchi G, Nguyen D, Wu J, Lucas D, Ma D, Isaacs L, Briken V. Toxicology and drug delivery by cucurbit[n]uril type molecular containers. Plos One. 5: e10514. PMID 20463906 DOI: 10.1371/Journal.Pone.0010514  0.645
2010 Ma D, Gargulakova Z, Zavalij PY, Sindelar V, Isaacs L. Reasons why aldehydes do not generally participate in cucurbit[n]uril forming reactions. The Journal of Organic Chemistry. 75: 2934-41. PMID 20345157 DOI: 10.1021/Jo100186Q  0.499
2010 Ghosh S, Isaacs L. Biological catalysis regulated by cucurbit[7]uril molecular containers. Journal of the American Chemical Society. 132: 4445-54. PMID 20210325 DOI: 10.1021/Ja910915K  0.526
2010 Wu J, Isaacs L. Cucurbit[7]uril complexation drives thermal trans-cis-azobenzene isomerization and enables colorimetric amine detection. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 11675-80. PMID 19774569 DOI: 10.1002/Chem.200901522  0.335
2010 Hettiarachchi G, Nguyen D, Wu J, Lucas D, Ma D, Isaacs L, Briken V. Abstract 5528: Toxicology and drug delivery by Cucurbit[n]urils and derivatives Cancer Research. 70: 5528-5528. DOI: 10.1158/1538-7445.Am10-5528  0.626
2010 Nally R, Scherman OA, Isaacs L. Polymer deaggregation and assembly controlled by a double cavity cucurbituril Supramolecular Chemistry. 22: 683-690. DOI: 10.1080/10610278.2010.497213  0.763
2009 Fedorova OA, Chernikova EY, Fedorov YV, Gulakova EN, Peregudov AS, Lyssenko KA, Jonusauskas G, Isaacs L. Cucurbit[7]uril complexes of crown-ether derived styryl and (bis)styryl dyes. The Journal of Physical Chemistry. B. 113: 10149-58. PMID 19719283 DOI: 10.1021/Jp903289Q  0.36
2009 Huang WH, Zavalij PY, Isaacs L. Metal-ion-induced folding and dimerization of a glycoluril decamer in water. Organic Letters. 11: 3918-21. PMID 19655803 DOI: 10.1021/Ol901539Q  0.481
2009 She N, Gao M, Cao L, Wu A, Isaacs L. Sensor for nitrophenol based on a fluorescent molecular clip. Organic Letters. 11: 2603-6. PMID 19449886 DOI: 10.1021/Ol900858D  0.313
2009 Nally R, Isaacs L. Toward supramolecular polymers incorporating double cavity cucurbituril hosts Tetrahedron. 65: 7249-7258. DOI: 10.1016/J.Tet.2009.02.055  0.787
2008 Huang WH, Zavalij PY, Isaacs L. Cucurbit[6]uril p-xylylenediammonium diiodide deca-hydrate inclusion complex. Acta Crystallographica. Section E, Structure Reports Online. 64: o1321-2. PMID 21202946 DOI: 10.1107/S1600536808018412  0.526
2008 She N, Meng X, Gao M, Wu A, Isaacs L. Tetrameric molecular bowl assembled from glycoluril building blocks Chemical Communications. 3133-3135. PMID 18594719 DOI: 10.1039/B800785C  0.312
2008 Ghosh S, Wu A, Fettinger JC, Zavalij PY, Isaacs L. Self-sorting molecular clips. The Journal of Organic Chemistry. 73: 5915-25. PMID 18588344 DOI: 10.1021/Jo8009424  0.537
2008 Huang WH, Zavalij PY, Isaacs L. Cucurbit[n]uril formation proceeds by step-growth cyclo-oligomerization. Journal of the American Chemical Society. 130: 8446-54. PMID 18529059 DOI: 10.1021/Ja8013693  0.578
2008 Huang WH, Zavalij PY, Isaacs L. Folding of long-chain alkanediammonium ions promoted by a cucurbituril derivative. Organic Letters. 10: 2577-80. PMID 18503277 DOI: 10.1021/Ol800893N  0.513
2008 Nichols JM, Liu Y, Zavalij P, Isaacs L, Doyle MP. Diphenylglycoluril as a novel ligand architecture for dirhodium(II) carboxamidates Inorganica Chimica Acta. 361: 3309-3314. DOI: 10.1016/J.Ica.2007.12.001  0.307
2007 Rekharsky MV, Mori T, Yang C, Ko YH, Selvapalam N, Kim H, Sobransingh D, Kaifer AE, Liu S, Isaacs L, Chen W, Moghaddam S, Gilson MK, Kim K, Inoue Y. A synthetic host-guest system achieves avidin-biotin affinity by overcoming enthalpy-entropy compensation. Proceedings of the National Academy of Sciences of the United States of America. 104: 20737-42. PMID 18093926 DOI: 10.1073/Pnas.0706407105  0.35
2007 Huang WH, Zavalij PY, Isaacs L. Chiral recognition inside a chiral cucurbituril. Angewandte Chemie (International Ed. in English). 46: 7425-7. PMID 17694587 DOI: 10.1002/Anie.200702189  0.464
2007 Liu S, Kim K, Isaacs L. Mechanism of the conversion of inverted CB[6] to CB[6]. The Journal of Organic Chemistry. 72: 6840-7. PMID 17676913 DOI: 10.1021/Jo071034T  0.367
2007 Chakrabarti S, Mukhopadhyay P, Lin S, Isaacs L. Reconfigurable four-component molecular switch based on pH-controlled guest swapping. Organic Letters. 9: 2349-52. PMID 17500562 DOI: 10.1021/Ol070730C  0.631
2007 Huang W, Zavalij PY, Isaacs L. Cucurbit[6]uril p-phenyl­enediammonium diiodide deca­hydrate inclusion complex Acta Crystallographica Section E: Crystallographic Communications. 63. DOI: 10.1107/S160053680700387X  0.493
2007 Isaacs L, Chin DN, Bowden N, Xia Y, Whitesides GM. Self-Assembling Systems on Scales from Nanometers to Millimeters: Design and Discovery Supramolecular Materials and Technologies. 4: 1-46. DOI: 10.1002/9780470511497.ch1  0.608
2006 Huang WH, Liu S, Zavalij PY, Isaacs L. Nor-seco-cucurbit[10]uril exhibits homotropic allosterism. Journal of the American Chemical Society. 128: 14744-5. PMID 17105250 DOI: 10.1021/Ja064776X  0.537
2006 Mukhopadhyay P, Zavalij PY, Isaacs L. High fidelity kinetic self-sorting in multi-component systems based on guests with multiple binding epitopes. Journal of the American Chemical Society. 128: 14093-102. PMID 17061892 DOI: 10.1021/Ja063390J  0.673
2006 Wang ZG, Zhou BH, Chen YF, Yin GD, Li YT, Wu AX, Isaacs L. Substituent effects control the self-association of molecular clips in the crystalline state. The Journal of Organic Chemistry. 71: 4502-8. PMID 16749780 DOI: 10.1021/Jo0603375  0.311
2006 Lagona J, Wagner BD, Isaacs L. Molecular-recognition properties of a water-soluble cucurbit[6]uril analogue Journal of Organic Chemistry. 71: 1181-1190. PMID 16438536 DOI: 10.1021/Jo052294I  0.793
2006 Lagona J, Fettinger JC, Isaacs L. Cucurbit[n]uril analogues: synthetic and mechanistic studies. The Journal of Organic Chemistry. 70: 10381-92. PMID 16323848 DOI: 10.1021/Jo051655R  0.793
2005 Wagner BD, Roland PG, Lagona J, Isaacs L. A Cucurbit[6]uril analogue: Host properties monitored by fluorescence spectroscopy Journal of Physical Chemistry B. 109: 7686-7691. PMID 16851892 DOI: 10.1021/Jp044369C  0.782
2005 Isaacs L, Park SK, Liu S, Ko YH, Selvapalam N, Kim Y, Kim H, Zavalij PY, Kim GH, Lee HS, Kim K. The inverted cucurbit[n]uril family. Journal of the American Chemical Society. 127: 18000-1. PMID 16366540 DOI: 10.1021/Ja056988K  0.355
2005 Liu S, Ruspic C, Mukhopadhyay P, Chakrabarti S, Zavalij PY, Isaacs L. The cucurbit[n]uril family: prime components for self-sorting systems. Journal of the American Chemical Society. 127: 15959-67. PMID 16277540 DOI: 10.1021/Ja055013X  0.698
2005 Lagona J, Mukhopadhyay P, Chakrabarti S, Isaacs L. The cucurbit[n]uril family. Angewandte Chemie (International Ed. in English). 44: 4844-70. PMID 16052668 DOI: 10.1002/Anie.200460675  0.782
2005 Isaacs L, Lagona J. Chapter 3 From methylene bridged glycoluril dimers to cucurbit[n]uril analogs with some detours along the way Strategies and Tactics in Organic Synthesis. 6: 71-99. DOI: 10.1016/S1874-6004(05)80026-7  0.796
2005 Lagona J, Mukhopadhyay P, Chakrabarti S, Isaacs L. Die Cucurbit[n]uril‐Familie Angewandte Chemie. 117: 4922-4949. DOI: 10.1002/Ange.200460675  0.757
2004 Mukhopadhyay P, Wu A, Isaacs L. Social self-sorting in aqueous solution. The Journal of Organic Chemistry. 69: 6157-64. PMID 15357573 DOI: 10.1021/Jo049976A  0.665
2004 Wu A, Mukhopadhyay P, Chakraborty A, Fettinger JC, Isaacs L. Molecular clips form isostructural dimeric aggregates from benzene to water. Journal of the American Chemical Society. 126: 10035-43. PMID 15303878 DOI: 10.1021/Ja0486972  0.674
2004 Lagona J, Fettinger JC, Isaacs L. Cucurbit[n]uril analogues. Organic Letters. 5: 3745-7. PMID 14507220 DOI: 10.1021/Ol035468W  0.78
2003 Burnett CA, Witt D, Fettinger JC, Isaacs L. Acyclic congener of cucurbituril: synthesis and recognition properties. The Journal of Organic Chemistry. 68: 6184-91. PMID 12895048 DOI: 10.1021/Jo034399W  0.408
2003 Burnett CA, Lagona J, Wu A, Shaw JA, Coady D, Fettinger JC, Day AI, Isaacs L. Preparation of glycoluril monomers for expanded cucurbit[n]uril synthesis Tetrahedron. 59: 1961-1970. DOI: 10.1016/S0040-4020(03)00150-9  0.776
2002 Wu A, Chakraborty A, Witt D, Lagona J, Damkaci F, Ofori MA, Chiles JK, Fettinger JC, Isaacs L. Methylene-bridged glycoluril dimers: synthetic methods. The Journal of Organic Chemistry. 67: 5817-30. PMID 12153286 DOI: 10.1021/Jo0258958  0.784
2002 Chakraborty A, Wu A, Witt D, Lagona J, Fettinger JC, Isaacs L. Diastereoselective formation of glycoluril dimers: isomerization mechanism and implications for cucurbit[n]uril synthesis. Journal of the American Chemical Society. 124: 8297-306. PMID 12105910 DOI: 10.1021/Ja025876F  0.799
2002 Wu A, Fettinger JC, Isaacs L. Glycoluril derivatives form hydrogen bonded tapes rather than cucurbit[ n ]uril congeners Tetrahedron. 58: 9769-9777. DOI: 10.1016/S0040-4020(02)01307-8  0.324
2001 Isaacs L, Witt D, Lagona J. Self-association of facially amphiphilic methylene bridged glycoluril dimers. Organic Letters. 3: 3221-4. PMID 11574036 DOI: 10.1021/Ol016561S  0.771
2000 Witt D, Lagona J, Damkaci F, Fettinger JC, Isaacs L. Diastereoselective Formation of Methylene-Bridged Glycoluril Dimers. Organic Letters. 2: 755-758. PMID 10814425 DOI: 10.1021/Ol991382K  0.788
1999 Lahiri J, Isaacs L, Tien J, Whitesides GM. A strategy for the generation of surfaces presenting ligands for studies of binding based on an active ester as a common reactive intermediate: a surface plasmon resonance study. Analytical Chemistry. 71: 777-90. PMID 10051846 DOI: 10.1021/Ac980959T  0.686
1999 Lahiri J, Isaacs L, Grzybowski B, Carbeck JD, Whitesides GM. Biospecific Binding of Carbonic Anhydrase to Mixed SAMs Presenting Benzenesulfonamide Ligands:  A Model System for Studying Lateral Steric Effects Langmuir. 15: 7186-7198. DOI: 10.1021/La9815650  0.74
1998 Rao J, Lahiri J, Isaacs L, Weis RM, Whitesides GM. A trivalent system from vancomycin.D-ala-D-Ala with higher affinity than avidin.biotin. Science (New York, N.Y.). 280: 708-11. PMID 9563940 DOI: 10.1126/Science.280.5364.708  0.577
1998 Boudon C, Gisselbrecht J, Gross M, Thiel W, Cardullo F, Seiler P, Isaacs L, Nierengarten J, Haldimann RF, Diederich F, Mordasini-Denti T. Propriétés rédox de fullerènes fonctionnalisés The Canadian Journal of Chemical Engineering. 76: 1008-1012. DOI: 10.1002/Cjce.5450760606  0.378
1997 Simanek EE, Isaacs L, Li X, Wang CCC, Whitesides GM. Self-Assembly of Zinc Porphyrins around the Periphery of Hydrogen-Bonded Aggregates That Bear Imidazole Groups The Journal of Organic Chemistry. 62: 8994-9000. DOI: 10.1021/Jo9615458  0.636
1997 Colton IJ, Anderson JR, Gao J, Chapman RG, Isaacs L, Whitesides GM. Formation of Protein Charge Ladders by Acylation of Amino Groups on Proteins Journal of the American Chemical Society. 119: 12701-12709. DOI: 10.1021/Ja9723491  0.551
1997 Cardullo F, Seiler P, Isaacs L, Nierengarten J, Haldimann RF, Diederich F, Mordasini-Denti T, Thiel W, Boudon C, Gisselhrccht J, Gross M. Bis- through Tetrakis-Adducts of C60 by Reversible Tether-Directed Remote Functionalization and systematic investigation of the changes in fullerene properties as a function of degree, pattern, and nature of functionalization Helvetica Chimica Acta. 80: 343-371. DOI: 10.1002/Hlca.19970800203  0.505
1997 Isaacs L, Diederich F, Haldimann RF. Multiple Adducts of C60 by Tether-Directed Remote Functionalization and synthesis of soluble derivatives of new carbon allotropes Cn(60+5) Helvetica Chimica Acta. 80: 317-342. DOI: 10.1002/Hlca.19970800202  0.469
1997 Rüttimann M, Haldimann RF, Isaacs L, Diederich F, Khong A, Jiménez-Vázquez H, Cross RJ, Saunders M. π-Electron Ring-Current Effects in Multiple Adducts of3He@C60 and3He@C70: A3He NMR Study Chemistry - a European Journal. 3: 1071-1076. DOI: 10.1002/Chem.19970030714  0.448
1996 Cardullo F, Isaacs L, Diederich F, Gisselbrecht J, Boudon C, Gross M. Regiospecific templated synthesis of D2h-symmetrical tetrakis-adduct C64(COOEt)8 by reversible tether-directed remote functionalization of C60 Chemical Communications. 797-799. DOI: 10.1039/Cc9960000797  0.469
1996 Seiler P, Isaacs L, Diederich F. The X-Ray Crystal Structure and Packing of a Hexakis-adduct of C60: Temperature dependence of weak C?H?O interactions Helvetica Chimica Acta. 79: 1047-1058. DOI: 10.1002/Hlca.19960790413  0.427
1995 Boudon C, Gisselbrecht J, Gross M, Isaacs L, Anderson HL, Faust R, Diederich F. Electrochemistry of Mono- through Hexakis-adducts of C60 Helvetica Chimica Acta. 78: 1334-1344. DOI: 10.1002/Hlca.19950780523  0.73
1995 Jonas U, Cardullo F, Belik P, Diederich F, Gügel A, Harth E, Herrmann A, Isaacs L, Müllen K, Ringsdorf H, Thilgen C, Uhlmann P, Vasella A, Waldraff CAA, Walter M. Synthesis of a Fullerene[60] Cryptate and Systematic Langmuir-Blodgett and Thin-Film Investigations of Amphiphilic Fullerene Derivatives Chemistry - a European Journal. 1: 243-251. DOI: 10.1002/Chem.19950010408  0.676
1995 Isaacs L, Seiler P, Diederich F. Solubilized Derivatives of C195 and C260: The First Members of a New Class of Carbon Allotropes Cn(60+ 5) Angewandte Chemie International Edition in English. 34: 1466-1469. DOI: 10.1002/Anie.199514661  0.415
1995 Isaacs L, Seiler P, Diederich F. Lösliche Derivate von C195 und C260: die ersten Verbindungen einer neuen Klasse von Kohlenstoffallotropen Cn(60 + 5) Angewandte Chemie. 107: 1636-1639. DOI: 10.1002/Ange.19951071336  0.408
1994 Diederich F, Isaacs L, Philp D. Valence isomerism and rearrangements in methanofullerenes Journal of the Chemical Society-Perkin Transactions 1. 391-394. DOI: 10.1039/P29940000391  0.421
1994 Diederich F, Isaacs L, Philp D. Syntheses, structures, and properties of methanofullerenes Chemical Society Reviews. 23: 243. DOI: 10.1039/Cs9942300243  0.421
1994 Isaacs L, Haldimann RF, Diederich F. Tether-Directed Remote Functionalization of Buckminsterfullerene: Regiospecific Hexaadduct Formation Angewandte Chemie International Edition in English. 33: 2339-2342. DOI: 10.1002/Anie.199423391  0.403
1994 Isaacs L, Haldimann RF, Diederich F. Spacer-kontrollierte Fernfunktionalisierung von Buckminsterfulleren: regiospezifische Bildung eines Hexaadduktes Angewandte Chemie. 106: 2434-2437. DOI: 10.1002/Ange.19941062237  0.395
1993 Isaacs L, Diederich F. Structures and Chemistry of Methanofullerenes: A Versatile Route intoN-[(Methanofullerene)carbonyl]-Substituted Amino Acids Helvetica Chimica Acta. 76: 2454-2464. DOI: 10.1002/Hlca.19930760705  0.448
1993 Isaacs L, Wehrsig A, Diederich F. Improved Purification of C60 and Formation of ?- and ?-Homoaromatic methano-bridged fullerenes by reaction with alkyl diazoacetates Helvetica Chimica Acta. 76: 1231-1250. DOI: 10.1002/Hlca.19930760310  0.429
1992 Bunshah RF, Jou S, Prakash S, Doerr HJ, Isaacs L, Wehrsig A, Yeretzian C, Cynn H, Diederich F. Fullerene formation in sputtering and electron beam evaporation processes The Journal of Physical Chemistry. 96: 6866-6869. DOI: 10.1021/J100196A005  0.426
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