Michael G. Roper, PhD - Publications

2006- Department of Chemistry & Biochemistry Florida State University, Tallahassee, FL, United States 
Analytical chemistry, microfluidics, islet biology

68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Donohue MJ, Filla RT, Steyer DJ, Eaton WJ, Roper MG. Rapid liquid chromatography-mass spectrometry quantitation of glucose-regulating hormones from human islets of Langerhans. Journal of Chromatography. A. 1637: 461805. PMID 33360778 DOI: 10.1016/j.chroma.2020.461805  1
2020 Wang Y, Adeoye DI, Ogunkunle EO, Wei IA, Filla RT, Roper MG. Affinity Capillary Electrophoresis: A Critical Review of the Literature from 2018 to 2020. Analytical Chemistry. PMID 33185441 DOI: 10.1021/acs.analchem.0c04526  1
2020 Beesley S, Sullenberger T, Crotty K, Ailani R, D'Orio C, Evans K, Ogunkunle EO, Roper MG, Kumar SS. D-serine mitigates cell loss associated with temporal lobe epilepsy. Nature Communications. 11: 4966. PMID 33009404 DOI: 10.1038/s41467-020-18757-2  1
2020 Adablah JE, Wang Y, Donohue M, Roper MG. Profiling Glucose-Stimulated and M3 Receptor-Activated Insulin Secretion Dynamics from Islets of Langerhans Using an Extended-Lifetime Fluorescence Dye. Analytical Chemistry. PMID 32429660 DOI: 10.1021/Acs.Analchem.0C01226  1
2019 Leng W, Evans K, Roper MG. A microfluidic platform integrating pressure-driven and electroosmotic-driven flow with inline filters for affinity separations. Analytical Methods : Advancing Methods and Applications. 11: 5768-5775. PMID 31983930 DOI: 10.1039/C9Ay01758E  1
2019 Glieberman AL, Pope BD, Zimmerman JF, Liu Q, Ferrier JP, Kenty JHR, Schrell AM, Mukhitov N, Shores KL, Tepole AB, Melton DA, Roper MG, Parker KK. Synchronized stimulation and continuous insulin sensing in a microfluidic human Islet on a Chip designed for scalable manufacturing. Lab On a Chip. PMID 31464325 DOI: 10.1039/C9Lc00253G  1
2019 Evans K, Wang X, Roper MG. Chiral micellar electrokinetic chromatographic separation for determination of L- and D-primary amines released from murine islets of Langerhans. Analytical Methods : Advancing Methods and Applications. 11: 1276-1283. PMID 31073338 DOI: 10.1039/C8Ay02471E  1
2019 Mukhitov N, Adablah JE, Roper MG. Gene expression patterns in synchronized islet populations. Islets. 1-12. PMID 31050588 DOI: 10.1080/19382014.2019.1581544  1
2019 Adams AG, Bulusu RKM, Mukhitov N, Mendoza-Cortes JL, Roper MG. Online Measurement of Glucose Consumption from HepG2 Cells Using an Integrated Bioreactor and Enzymatic Assay. Analytical Chemistry. PMID 30884946 DOI: 10.1021/Acs.Analchem.8B05798  1
2019 Adablah JE, Vinson R, Roper MG, Bertram R. Synchronization of pancreatic islets by periodic or non-periodic muscarinic agonist pulse trains. Plos One. 14: e0211832. PMID 30726280 DOI: 10.1371/Journal.Pone.0211832  1
2018 Bandak B, Yi L, Roper MG. Microfluidic-enabled quantitative measurements of insulin release dynamics from single islets of Langerhans in response to 5-palmitic acid hydroxy stearic acid. Lab On a Chip. PMID 30109329 DOI: 10.1039/C8Lc00624E  1
2018 Filla RT, Schrell AM, Coulton JB, Edwards JL, Roper MG. Frequency-Modulated Continuous Flow Analysis Electrospray Ionization Mass Spectrometry (FM-CFA-ESI-MS) for Sample Multiplexing. Analytical Chemistry. PMID 29356503 DOI: 10.1021/Acs.Analchem.7B04669  1
2017 Schrell AM, Mukhitov N, Yi L, Adablah JE, Menezes J, Roper MG. Online fluorescence anisotropy immunoassay for monitoring insulin secretion from islets of Langerhans. Analytical Methods : Advancing Methods and Applications. 9: 38-45. PMID 28458724 DOI: 10.1039/C6Ay02899C  1
2016 McKenna JP, Dhumpa R, Mukhitov N, Roper MG, Bertram R. Glucose Oscillations Can Activate an Endogenous Oscillator in Pancreatic Islets. Plos Computational Biology. 12: e1005143. PMID 27788129 DOI: 10.1371/Journal.Pcbi.1005143  1
2016 Yi L, Bandak B, Wang X, Bertram R, Roper MG. A dual detection system for simultaneous measurement of intracellular fluorescent markers and cellular secretion. Analytical Chemistry. PMID 27712062 DOI: 10.1021/Acs.Analchem.6B02404  1
2016 Schrell AM, Mukhitov N, Roper MG. Multiplexing fluorescence anisotropy using frequency encoding. Analytical Chemistry. PMID 27440478 DOI: 10.1021/Acs.Analchem.6B02131  1
2016 Schrell AM, Mukhitov N, Yi L, Wang X, Roper MG. Microfluidic Devices for the Measurement of Cellular Secretion. Annual Review of Analytical Chemistry (Palo Alto, Calif.). 9: 249-69. PMID 27306310 DOI: 10.1146/Annurev-Anchem-071114-040409  1
2016 Wang X, Yi L, Roper MG. Microfluidic device for the measurement of amino acid secretion dynamics from murine and human islets of Langerhans. Analytical Chemistry. PMID 26891222 DOI: 10.1021/Acs.Analchem.6B00071  1
2016 Yi L, Wang X, Bethge L, Klussmann S, Roper MG. Noncompetitive affinity assays of glucagon and amylin using mirror-image aptamers as affinity probes. The Analyst. PMID 26881276 DOI: 10.1039/C5An02468D  1
2015 Mukhitov N, Spear JM, Stagg S, Roper MG. Interfacing Microfluidics with Negative Stain Transmission Electron Microscopy. Analytical Chemistry. PMID 26642355 DOI: 10.1021/Acs.Analchem.5B03884  1
2015 Roper MG. Cellular Analysis using Microfluidics. Analytical Chemistry. PMID 26620153 DOI: 10.1021/Acs.Analchem.5B04532  1
2015 Dhumpa R, Truong TM, Wang X, Roper MG. Measurement of the entrainment window of islets of Langerhans by microfluidic delivery of a chirped glucose waveform. Integrative Biology : Quantitative Biosciences From Nano to Macro. 7: 1061-7. PMID 26211670 DOI: 10.1039/C5Ib00156K  1
2015 Wang X, Yi L, Guillo C, Roper MG. Micellar electrokinetic chromatography method for measuring amino acid secretions from islets of Langerhans. Electrophoresis. 36: NA. PMID 25974017 DOI: 10.1002/elps.201570081  1
2015 Wang X, Yi L, Guillo C, Roper MG. Micellar electrokinetic chromatography method for measuring amino acid secretions from islets of Langerhans. Electrophoresis. 36: 1172-8. PMID 25780900 DOI: 10.1002/Elps.201400569  1
2015 Yi L, Wang X, Dhumpa R, Schrell AM, Mukhitov N, Roper MG. Integrated perfusion and separation systems for entrainment of insulin secretion from islets of Langerhans. Lab On a Chip. 15: 823-32. PMID 25474044 DOI: 10.1039/C4Lc01360C  1
2015 Wang X, Yi L, Mukhitov N, Schrell AM, Dhumpa R, Roper MG. Microfluidics-to-mass spectrometry: a review of coupling methods and applications. Journal of Chromatography. A. 1382: 98-116. PMID 25458901 DOI: 10.1016/J.Chroma.2014.10.039  1
2014 Mukhitov N, Yi L, Schrell AM, Roper MG. Optimization of a microfluidic electrophoretic immunoassay using a Peltier cooler. Journal of Chromatography. A. 1367: 154-60. PMID 25263064 DOI: 10.1016/J.Chroma.2014.09.040  1
2014 Wang X, Roper MG. Measurement of DCF fluorescence as a measure of reactive oxygen species in murine islets of Langerhans. Analytical Methods : Advancing Methods and Applications. 6: 3019-3024. PMID 24955137 DOI: 10.1039/C4Ay00288A  1
2014 Dhumpa R, Truong TM, Wang X, Bertram R, Roper MG. Negative feedback synchronizes islets of Langerhans. Biophysical Journal. 106: 2275-82. PMID 24853756 DOI: 10.1016/J.Bpj.2014.04.015  1
2014 Schrell AM, Roper MG. Frequency-encoded laser-induced fluorescence for multiplexed detection in infrared-mediated quantitative PCR. The Analyst. 139: 2695-701. PMID 24448431 DOI: 10.1039/C3An02334F  1
2014 Mukhitov N, Yi L, Schrell AM, Wang X, Dhumpa R, Roper MG. Temperature-controlled separations for improving the sensitivity of multi-color microfluidic immunoassays 18th International Conference On Miniaturized Systems For Chemistry and Life Sciences, Microtas 2014. 2429-2431.  1
2013 Zhang X, Dhumpa R, Roper MG. Maintaining Stimulant Waveforms in Large Volume Microfluidic Cell Chambers. Microfluidics and Nanofluidics. 15. PMID 24244207 DOI: 10.1007/S10404-012-1129-X  1
2013 Lomasney AR, Yi L, Roper MG. Simultaneous monitoring of insulin and islet amyloid polypeptide secretion from islets of Langerhans on a microfluidic device. Analytical Chemistry. 85: 7919-25. PMID 23848226 DOI: 10.1021/Ac401625G  1
2013 Dhumpa R, Truong TM, Wang X, Roper MG. Microfluidic system for mimicking interactions between pancreas and peripheral tissues 17th International Conference On Miniaturized Systems For Chemistry and Life Sciences, Microtas 2013. 2: 1096-1098.  1
2013 Yi L, Lomasney AR, Roper MG. Dual-color microfluidic immunoassays for monitoring release of multiple peptides from islets of langerhans 17th International Conference On Miniaturized Systems For Chemistry and Life Sciences, Microtas 2013. 1: 554-556.  1
2012 Dhumpa R, Roper MG. Temporal gradients in microfluidic systems to probe cellular dynamics: a review. Analytica Chimica Acta. 743: 9-18. PMID 22882819 DOI: 10.1016/J.Aca.2012.07.006  1
2012 Yu Y, Li B, Baker CA, Zhang X, Roper MG. Quantitative polymerase chain reaction using infrared heating on a microfluidic chip. Analytical Chemistry. 84: 2825-9. PMID 22385579 DOI: 10.1021/Ac203307H  1
2012 Baker CA, Roper MG. Online coupling of digital microfluidic devices with mass spectrometry detection using an eductor with electrospray ionization. Analytical Chemistry. 84: 2955-60. PMID 22384846 DOI: 10.1021/Ac300100B  1
2012 Duong CT, Roper MG. A microfluidic device for the automated derivatization of free fatty acids to fatty acid methyl esters. The Analyst. 137: 840-6. PMID 22166918 DOI: 10.1039/C2An15911B  1
2011 Zhang X, Daou A, Truong TM, Bertram R, Roper MG. Synchronization of mouse islets of Langerhans by glucose waveforms. American Journal of Physiology. Endocrinology and Metabolism. 301: E742-7. PMID 21771970 DOI: 10.1152/Ajpendo.00248.2011  1
2011 Guillo C, Truong TM, Roper MG. Simultaneous capillary electrophoresis competitive immunoassay for insulin, glucagon, and islet amyloid polypeptide secretion from mouse islets of Langerhans. Journal of Chromatography. A. 1218: 4059-64. PMID 21620410 DOI: 10.1016/J.Chroma.2011.05.006  1
2011 Baker CA, Bulloch R, Roper MG. Comparison of separation performance of laser-ablated and wet-etched microfluidic devices. Analytical and Bioanalytical Chemistry. 399: 1473-9. PMID 20827468 DOI: 10.1007/S00216-010-4144-3  1
2011 Roper MG, Zhang X, Dhumpa R, Truong TM. Modeling and experimental verification of channel geometry for delivery of stimulant waveforms to large volume chambers for cellular synchronization 15th International Conference On Miniaturized Systems For Chemistry and Life Sciences 2011, Microtas 2011. 2: 909-911.  1
2010 Cao L, Zhang X, Grimley A, Lomasney AR, Roper MG. Microfluidic multi-analyte gradient generator. Analytical and Bioanalytical Chemistry. 398: 1985-91. PMID 20835814 DOI: 10.1007/S00216-010-4168-8  1
2010 Baker CA, Roper MG. A continuous-flow, microfluidic fraction collection device. Journal of Chromatography. A. 1217: 4743-8. PMID 20730040 DOI: 10.1016/J.Chroma.2010.05.023  1
2010 Zhang X, Grimley A, Bertram R, Roper MG. Microfluidic system for generation of sinusoidal glucose waveforms for entrainment of islets of Langerhans. Analytical Chemistry. 82: 6704-11. PMID 20617825 DOI: 10.1021/Ac101461X  1
2009 Baker CA, Duong CT, Grimley A, Roper MG. Recent advances in microfluidic detection systems. Bioanalysis. 1: 967-75. PMID 20414455 DOI: 10.4155/Bio.09.86  1
2009 Lomasney AR, Guillo C, Sidebottom AM, Roper MG. Optimization of capillary electrophoresis conditions for a glucagon competitive immunoassay using response surface methodology. Analytical and Bioanalytical Chemistry. 394: 313-9. PMID 19189083 DOI: 10.1007/S00216-009-2622-2  1
2009 Zhang X, Roper MG. Microfluidic perfusion system for automated delivery of temporal gradients to islets of Langerhans. Analytical Chemistry. 81: 1162-8. PMID 19178342 DOI: 10.1021/Ac802579Z  1
2009 Roper MG, Guillo C. New technologies in affinity assays to explore biological communication. Analytical and Bioanalytical Chemistry. 393: 459-65. PMID 18759100 DOI: 10.1007/S00216-008-2347-7  1
2008 Guillo C, Roper MG. Affinity assays for detection of cellular communication and biomarkers. The Analyst. 133: 1481-5. PMID 18936823 DOI: 10.1039/B808735K  1
2008 Sloat AL, Roper MG, Lin X, Ferrance JP, Landers JP, Colyer CL. Protein determination by microchip capillary electrophoresis using an asymmetric squarylium dye: noncovalent labeling and nonequilibrium measurement of association constants. Electrophoresis. 29: 3446-55. PMID 18702052 DOI: 10.1002/Elps.200700808  1
2008 Tierno P, Reddy SV, Roper MG, Johansen TH, Fischer TM. Transport and separation of biomolecular cargo on paramagnetic colloidal particles in a magnetic ratchet. The Journal of Physical Chemistry. B. 112: 3833-7. PMID 18318526 DOI: 10.1021/Jp710596R  1
2008 Guillo C, Roper MG. Two-color electrophoretic immunoassay for simultaneous measurement of insulin and glucagon content in islets of Langerhans. Electrophoresis. 29: 410-6. PMID 18080249 DOI: 10.1002/Elps.200700399  1
2007 Roper MG, Easley CJ, Legendre LA, Humphrey JA, Landers JP. Infrared temperature control system for a completely noncontact polymerase chain reaction in microfluidic chips. Analytical Chemistry. 79: 1294-300. PMID 17297927 DOI: 10.1021/Ac0613277  1
2006 Yue GE, Roper MG, Balchunas C, Pulsipher A, Coon JJ, Shabanowitz J, Hunt DF, Landers JP, Ferrance JP. Protein digestion and phosphopeptide enrichment on a glass microchip. Analytica Chimica Acta. 564: 116-22. PMID 17723369 DOI: 10.1016/J.Aca.2005.11.003  1
2006 Easley CJ, Karlinsey JM, Bienvenue JM, Legendre LA, Roper MG, Feldman SH, Hughes MA, Hewlett EL, Merkel TJ, Ferrance JP, Landers JP. A fully integrated microfluidic genetic analysis system with sample-in-answer-out capability. Proceedings of the National Academy of Sciences of the United States of America. 103: 19272-7. PMID 17159153 DOI: 10.1073/Pnas.0604663103  1
2006 Legendre LA, Bienvenue JM, Roper MG, Ferrance JP, Landers JP. A simple, valveless microfluidic sample preparation device for extraction and amplification of DNA from nanoliter-volume samples. Analytical Chemistry. 78: 1444-51. PMID 16503592 DOI: 10.1021/Ac0516988  1
2006 Roper MG, Frisk ML, Oberlander JP, Ferrance JP, McGrory BJ, Landers JP. Extraction of C-reactive protein from serum on a microfluidic chip Analytica Chimica Acta. 569: 195-202. DOI: 10.1016/J.Aca.2006.03.096  1
2005 Roper MG, Easley CJ, Landers JP. Advances in polymerase chain reaction on microfluidic chips. Analytical Chemistry. 77: 3887-93. PMID 15952761 DOI: 10.1021/Ac050756M  1
2005 Yue GE, Roper MG, Jeffery ED, Easley CJ, Balchunas C, Landers JP, Ferrance JP. Glass microfluidic devices with thin membrane voltage junctions for electrospray mass spectrometry. Lab On a Chip. 5: 619-27. PMID 15915254 DOI: 10.1039/B502446C  1
2005 Easley CJ, Legendre LA, Roper MG, Wavering TA, Ferrance JP, Landers JP. Extrinsic Fabry-Perot interferometry for noncontact temperature control of nanoliter-volume enzymatic reactions in glass microchips. Analytical Chemistry. 77: 1038-45. PMID 15858983 DOI: 10.1021/Ac048693F  1
2005 Ferrance JP, Bienvenue J, Legendre L, Easley C, Karlinsey J, Roper MG, Landers JP. A fully integrated microdevice for clinical analysis Micro Total Analysis Systems - Proceedings of Microtas 2005 Conference: 9th International Conference On Miniaturized Systems For Chemistry and Life Sciences. 1: 794-795.  1
2004 Kulkarni RN, Roper MG, Dahlgren G, Shih DQ, Kauri LM, Peters JL, Stoffel M, Kennedy RT. Islet secretory defect in insulin receptor substrate 1 null mice is linked with reduced calcium signaling and expression of sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA)-2b and -3. Diabetes. 53: 1517-25. PMID 15161756 DOI: 10.2337/Diabetes.53.6.1517  1
2003 Roper MG, Shackman JG, Dahlgren GM, Kennedy RT. Microfluidic chip for continuous monitoring of hormone secretion from live cells using an electrophoresis-based immunoassay. Analytical Chemistry. 75: 4711-7. PMID 14674445 DOI: 10.1021/Ac0346813  1
2002 Roper MG, Qian WJ, Zhang BB, Kulkarni RN, Kahn CR, Kennedy RT. Effect of the insulin mimetic L-783,281 on intracellular Ca2+ and insulin secretion from pancreatic beta-cells. Diabetes. 51: S43-9. PMID 11815457 DOI: 10.2337/Diabetes.51.2007.S43  1
2001 German I, Roper MG, Kalra SP, Rhinehart E, Kennedy RT. Capillary liquid chromatography of multiple peptides with on-line capillary electrophoresis immunoassay detection. Electrophoresis. 22: 3659-67. PMID 11699903 DOI: 10.1002/1522-2683(200109)22:17<3659::Aid-Elps3659>3.0.Co;2-I  1
2000 Aspinwall CA, Qian WJ, Roper MG, Kulkarni RN, Kahn CR, Kennedy RT. Roles of insulin receptor substrate-1, phosphatidylinositol 3-kinase, and release of intracellular Ca2+ stores in insulin-stimulated insulin secretion in beta -cells. The Journal of Biological Chemistry. 275: 22331-8. PMID 10764813 DOI: 10.1074/Jbc.M909647199  1
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