Allen M. Spiegel, M.D. - Publications

Affiliations: 
NIH - NIDDK 
Area:
endocrinology, diabetis

228 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Hannan FM, Walls GV, Babinsky VN, Nesbit MA, Kallay E, Hough TA, Fraser WD, Cox RD, Hu J, Spiegel AM, Thakker RV. The calcilytic agent NPS 2143 rectifies hypocalcemia in a mouse model with an activating calcium-sensing-receptor (CaSR) mutation: relevance to autosomal dominant hypocalcemia type 1 (ADH1). Endocrinology. en20151269. PMID 26052899 DOI: 10.1210/en.2015-1269  0.68
2015 Levine AS, Alpern RJ, Andrews NC, Antman K, Balser JR, Berg JM, Davis PB, Fitz JG, Golden RN, Goldman L, Jameson JL, Lee VS, Polonsky KS, Rappley MD, Reece EA, ... ... Spiegel AM, et al. Research in academic medical centers: two threats to sustainable support. Science Translational Medicine. 7: 289fs22. PMID 26019216 DOI: 10.1126/scitranslmed.aac5200  0.68
2013 Spiegel AM. The stem cell wars: a dispatch from the front. Transactions of the American Clinical and Climatological Association. 124: 94-110. PMID 23874014  0.68
2013 Spiegel AM. G proteins--the disease spectrum expands. The New England Journal of Medicine. 368: 2515-6. PMID 23802519 DOI: 10.1056/NEJMe1304751  0.68
2013 Weinstein LS, Collins MT, Spiegel AM. Gsα, Pseudohypoparathyroidism, Fibrous Dysplasia, and McCune-Albright Syndrome Genetics of Bone Biology and Skeletal Disease. 425-440. DOI: 10.1016/B978-0-12-387829-8.00027-5  0.68
2012 Spiegel AM, Hawkins M. 'Personalized medicine' to identify genetic risks for type 2 diabetes and focus prevention: can it fulfill its promise? Health Affairs (Project Hope). 31: 43-9. PMID 22232093 DOI: 10.1377/hlthaff.2011.1054  0.68
2011 Spiegel AM, Libutti SK. Targeted therapies: Good news for advanced-stage pancreatic neuroendocrine tumors. Nature Reviews. Clinical Oncology. 8: 258-9. PMID 21448150 DOI: 10.1038/nrclinonc.2011.50  0.68
2010 Spiegel AM, Libutti SK. Future diagnostic and therapeutic trends in endocrine cancers. Seminars in Oncology. 37: 691-5. PMID 21167386 DOI: 10.1053/j.seminoncol.2010.10.020  0.68
2010 Spiegel AM. Commentary: new guidelines for NIH peer review: improving the system or undermining it? Academic Medicine : Journal of the Association of American Medical Colleges. 85: 746-8. PMID 20520019 DOI: 10.1097/ACM.0b013e3181d7e130  0.68
2009 Shen HC, He M, Powell A, Adem A, Lorang D, Heller C, Grover AC, Ylaya K, Hewitt SM, Marx SJ, Spiegel AM, Libutti SK. Recapitulation of pancreatic neuroendocrine tumors in human multiple endocrine neoplasia type I syndrome via Pdx1-directed inactivation of Men1. Cancer Research. 69: 1858-66. PMID 19208834 DOI: 10.1158/0008-5472.CAN-08-3662  0.68
2008 Spiegel A. Albert Einstein College of Medicine Academic Medicine : Journal of the Association of American Medical Colleges. 83: 524. PMID 18448914  0.68
2008 Shen HC, Rosen JE, Yang LM, Savage SA, Burns AL, Mateo CM, Agarwal SK, Chandrasekharappa SC, Spiegel AM, Collins FS, Marx SJ, Libutti SK. Parathyroid tumor development involves deregulation of homeobox genes. Endocrine-Related Cancer. 15: 267-75. PMID 18310293 DOI: 10.1677/ERC-07-0191  0.68
2007 Spiegel AM. Inherited endocrine diseases involving G proteins and G protein-coupled receptors. Endocrine Development. 11: 133-44. PMID 17986833 DOI: 10.1159/0000111069  0.68
2007 Hu J, Spiegel AM. Structure and function of the human calcium-sensing receptor: insights from natural and engineered mutations and allosteric modulators. Journal of Cellular and Molecular Medicine. 11: 908-22. PMID 17979873 DOI: 10.1111/j.1582-4934.2007.00096.x  0.68
2007 Agarwal SK, Impey S, McWeeney S, Scacheri PC, Collins FS, Goodman RH, Spiegel AM, Marx SJ. Distribution of menin-occupied regions in chromatin specifies a broad role of menin in transcriptional regulation. Neoplasia (New York, N.Y.). 9: 101-7. PMID 17356705 DOI: 10.1593/neo.06706  0.68
2007 Ozawa A, Agarwal SK, Mateo CM, Burns AL, Rice TS, Kennedy PA, Quigley CM, Simonds WF, Weinstein LS, Chandrasekharappa SC, Collins FS, Spiegel AM, Marx SJ. The parathyroid/pituitary variant of multiple endocrine neoplasia type 1 usually has causes other than p27Kip1 mutations. The Journal of Clinical Endocrinology and Metabolism. 92: 1948-51. PMID 17299066 DOI: 10.1210/jc.2006-2563  0.68
2007 Hu J, Reyes-Cruz G, Goldsmith PK, Gantt NM, Miller JL, Spiegel AM. Functional effects of monoclonal antibodies to the purified amino-terminal extracellular domain of the human Ca(2+) receptor. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 22: 601-8. PMID 17243861 DOI: 10.1359/jbmr.070111  0.68
2007 Wettschureck N, Lee E, Libutti SK, Offermanns S, Robey PG, Spiegel AM. Parathyroid-specific double knockout of Gq and G11 alpha-subunits leads to a phenotype resembling germline knockout of the extracellular Ca2+ -sensing receptor. Molecular Endocrinology (Baltimore, Md.). 21: 274-80. PMID 16988000 DOI: 10.1210/me.2006-0110  0.68
2006 Cerrato A, Parisi M, Anna SS, Missirlis F, Guru S, Agarwal S, Sturgill D, Talbot T, Spiegel A, Collins F, Chandrasekharappa S, Marx S, Oliver B. Genetic interactions between Drosophila melanogaster menin and Jun/Fos Developmental Biology. 298: 59-70. PMID 16930585 DOI: 10.1016/j.ydbio.2006.06.013  0.68
2006 Hu J, Jiang J, Costanzi S, Thomas C, Yang W, Feyen JH, Jacobson KA, Spiegel AM. A missense mutation in the seven-transmembrane domain of the human Ca2+ receptor converts a negative allosteric modulator into a positive allosteric modulator. The Journal of Biological Chemistry. 281: 21558-65. PMID 16735501 DOI: 10.1074/jbc.M603682200  0.68
2006 Scacheri PC, Davis S, Odom DT, Crawford GE, Perkins S, Halawi MJ, Agarwal SK, Marx SJ, Spiegel AM, Meltzer PS, Collins FS. Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis. Plos Genetics. 2: e51. PMID 16604156 DOI: 10.1371/journal.pgen.0020051  0.68
2006 Spiegel AM, Nabel EG. NIH research on obesity and type 2 diabetes: providing the scientific evidence base for actions to improve health. Nature Medicine. 12: 67-9. PMID 16397572 DOI: 10.1038/nm0106-67  0.68
2005 Spiegel AM, Alving BM. Executive summary of the Strategic Plan for National Institutes of Health Obesity Research. The American Journal of Clinical Nutrition. 82: 211S-214S. PMID 16002822  0.68
2005 Agarwal SK, Kennedy PA, Scacheri PC, Novotny EA, Hickman AB, Cerrato A, Rice TS, Moore JB, Rao S, Ji Y, Mateo C, Libutti SK, Oliver B, Chandrasekharappa SC, Burns AL, ... ... Spiegel AM, et al. Menin molecular interactions: insights into normal functions and tumorigenesis. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et MéTabolisme. 37: 369-74. PMID 16001329 DOI: 10.1055/s-2005-870139  0.68
2005 Rosen JE, Costouros NG, Lorang D, Burns AL, Alexander HR, Skarulis MC, Cochran C, Pingpank JF, Marx SJ, Spiegel AM, Libutti SK. Gland size is associated with changes in gene expression profiles in sporadic parathyroid adenomas. Annals of Surgical Oncology. 12: 412-6. PMID 15915376 DOI: 10.1245/ASO.2005.03.103  0.68
2005 Spiegel A, Nabel E, Volkow N, Landis S, Li TK. Obesity on the brain Nature Neuroscience. 8: 552-553. PMID 15856061 DOI: 10.1038/nn0505-552  0.68
2005 Elson CO, Ballew M, Barnard JA, Bernstein SJ, Check IJ, Cohen MB, Fazio S, Johanson JF, Lindor NM, Montgomery E, Richardson LH, Rogers D, Vijan S, Bushara KO, Case S, ... ... Spiegel AM, et al. National Institutes of Health Consensus Development Conference statement on Celiac Disease, June 28-30, 2004 Gastroenterology. 128: S1-S9. PMID 15825115 DOI: 10.1053/j.gastro.2005.02.007  0.68
2005 Hu J, McLarnon SJ, Mora S, Jiang J, Thomas C, Jacobson KA, Spiegel AM. A region in the seven-transmembrane domain of the human Ca2+ receptor critical for response to Ca2+. The Journal of Biological Chemistry. 280: 5113-20. PMID 15591042 DOI: 10.1074/jbc.M413403200  0.68
2004 Scacheri PC, Crabtree JS, Kennedy AL, Swain GP, Ward JM, Marx SJ, Spiegel AM, Collins FS. Homozygous loss of menin is well tolerated in liver, a tissue not affected in MEN1. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 15: 872-7. PMID 15672591 DOI: 10.1007/s00335-004-2395-z  0.68
2004 Spiegel AM. Focus on hereditary endocrine neoplasia. Cancer Cell. 6: 327-32. PMID 15488756 DOI: 10.1016/j.ccr.2004.09.023  0.68
2004 Scacheri PC, Kennedy AL, Chin K, Miller MT, Hodgson JG, Gray JW, Marx SJ, Spiegel AM, Collins FS. Pancreatic insulinomas in multiple endocrine neoplasia, type I knockout mice can develop in the absence of chromosome instability or microsatellite instability. Cancer Research. 64: 7039-44. PMID 15466197 DOI: 10.1158/0008-5472.CAN-04-1648  0.68
2004 Agarwal SK, Lee Burns A, Sukhodolets KE, Kennedy PA, Obungu VH, Hickman AB, Mullendore ME, Whitten I, Skarulis MC, Simonds WF, Mateo C, Crabtree JS, Scacheri PC, Ji Y, Novotny EA, ... ... Spiegel AM, et al. Molecular pathology of the MEN1 gene. Annals of the New York Academy of Sciences. 1014: 189-98. PMID 15153434 DOI: 10.1196/annals.1294.020  0.68
2004 Hu J, Mora S, Weber G, Zamproni I, Proverbio MC, Spiegel AM. Autosomal dominant hypocalcemia in monozygotic twins caused by a de novo germline mutation near the amino-terminus of the human calcium receptor. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 19: 578-86. PMID 15005845 DOI: 10.1359/JBMR.040106  0.68
2004 Spiegel AM, Weinstein LS. Inherited diseases involving g proteins and g protein-coupled receptors. Annual Review of Medicine. 55: 27-39. PMID 14746508 DOI: 10.1146/annurev.med.55.091902.103843  0.68
2003 Libutti SK, Crabtree JS, Lorang D, Burns AL, Mazzanti C, Hewitt SM, O'Connor S, Ward JM, Emmert-Buck MR, Remaley A, Miller M, Turner E, Alexander HR, Arnold A, Marx SJ, ... ... Spiegel AM, et al. Parathyroid gland-specific deletion of the mouse Men1 gene results in parathyroid neoplasia and hypercalcemic hyperparathyroidism. Cancer Research. 63: 8022-8. PMID 14633735  0.68
2003 Agarwal SK, Novotny EA, Crabtree JS, Weitzman JB, Yaniv M, Burns AL, Chandrasekharappa SC, Collins FS, Spiegel AM, Marx SJ. Transcription factor JunD, deprived of menin, switches from growth suppressor to growth promoter. Proceedings of the National Academy of Sciences of the United States of America. 100: 10770-5. PMID 12960363 DOI: 10.1073/pnas.1834524100  0.68
2003 Spiegel A. β-arrestin - Not just for G protein-coupled receptors Science. 301: 1338-1339. PMID 12958351 DOI: 10.1126/science.1089552  0.68
2003 Crabtree JS, Scacheri PC, Ward JM, McNally SR, Swain GP, Montagna C, Hager JH, Hanahan D, Edlund H, Magnuson MA, Garrett-Beal L, Burns AL, Ried T, Chandrasekharappa SC, Marx SJ, ... Spiegel AM, et al. Of mice and MEN1: Insulinomas in a conditional mouse knockout. Molecular and Cellular Biology. 23: 6075-85. PMID 12917331 DOI: 10.1128/MCB.23.17.6075-6085.2003  0.68
2003 Hu J, Spiegel AM. Naturally occurring mutations of the extracellular Ca2+-sensing receptor: implications for its structure and function. Trends in Endocrinology and Metabolism: Tem. 14: 282-8. PMID 12890593 DOI: 10.1016/S1043-2760(03)00104-8  0.68
2003 Sukhodolets KE, Hickman AB, Agarwal SK, Sukhodolets MV, Obungu VH, Novotny EA, Crabtree JS, Chandrasekharappa SC, Collins FS, Spiegel AM, Burns AL, Marx SJ. The 32-kilodalton subunit of replication protein A interacts with menin, the product of the MEN1 tumor suppressor gene. Molecular and Cellular Biology. 23: 493-509. PMID 12509449 DOI: 10.1128/MCB.23.2.493-509.2003  0.68
2003 Spiegel AM. G protein-regulated signaling dysfunction in human disease: A personal historical perspective Journal of Investigative Medicine. 51: 192-193.  0.68
2002 Marx SJ, Simonds WF, Agarwal SK, Burns AL, Weinstein LS, Cochran C, Skarulis MC, Spiegel AM, Libutti SK, Alexander HR, Chen CC, Chang R, Chandrasekharappa SC, Collins FS. Hyperparathyroidism in hereditary syndromes: special expressions and special managements. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 17: N37-43. PMID 12412776  0.68
2002 Hu J, Reyes-Cruz G, Chen W, Jacobson KA, Spiegel AM. Identification of acidic residues in the extracellular loops of the seven-transmembrane domain of the human Ca2+ receptor critical for response to Ca2+ and a positive allosteric modulator. The Journal of Biological Chemistry. 277: 46622-31. PMID 12297503 DOI: 10.1074/jbc.M207100200  0.68
2002 Hu J, Mora S, Colussi G, Proverbio MC, Jones KA, Bolzoni L, De Ferrari ME, Civati G, Spiegel AM. Autosomal dominant hypocalcemia caused by a novel mutation in the loop 2 region of the human calcium receptor extracellular domain. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 17: 1461-9. PMID 12162500 DOI: 10.1359/jbmr.2002.17.8.1461  0.68
2001 Valle MA, Kester MB, Burns AL, Marx SJ, Spiegel AM, Shiloach J. Production and purification of human menin from Drosophila melanogaster S2 cells using stirred tank reactor. Cytotechnology. 35: 127-35. PMID 19003289 DOI: 10.1023/A:1017586523710  0.68
2001 Scacheri PC, Crabtree JS, Novotny EA, Garrett-Beal L, Chen A, Edgemon KA, Marx SJ, Spiegel AM, Chandrasekharappa SC, Collins FS. Bidirectional transcriptional activity of PGK-neomycin and unexpected embryonic lethality in heterozygote chimeric knockout mice. Genesis (New York, N.Y. : 2000). 30: 259-63. PMID 11536432 DOI: 10.1002/gene.1072  0.68
2001 Heppner C, Bilimoria KY, Agarwal SK, Kester M, Whitty LJ, Guru SC, Chandrasekharappa SC, Collins FS, Spiegel AM, Marx SJ, Burns AL. The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivation. Oncogene. 20: 4917-25. PMID 11526476 DOI: 10.1038/sj.onc.1204529  0.68
2001 Reyes-Cruz G, Hu J, Goldsmith PK, Steinbach PJ, Spiegel AM. Human Ca(2+) receptor extracellular domain. Analysis of function of lobe I loop deletion mutants. The Journal of Biological Chemistry. 276: 32145-51. PMID 11399760 DOI: 10.1074/jbc.M102977200  0.68
2001 Schussheim DH, Skarulis MC, Agarwal SK, Simonds WF, Burns AL, Spiegel AM, Marx SJ. Multiple endocrine neoplasia type 1: new clinical and basic findings. Trends in Endocrinology and Metabolism: Tem. 12: 173-8. PMID 11295574  0.68
2001 Hu J, Reyes-Cruz G, Goldsmith PK, Spiegel AM. The Venus's-flytrap and cysteine-rich domains of the human Ca2+ receptor are not linked by disulfide bonds. The Journal of Biological Chemistry. 276: 6901-4. PMID 11238442 DOI: 10.1074/jbc.C000865200  0.68
2001 Guru SC, Prasad NB, Shin EJ, Hemavathy K, Lu J, Ip YT, Agarwal SK, Marx SJ, Spiegel AM, Collins FS, Oliver B, Chandrasekharappa SC. Characterization of a MEN1 ortholog from Drosophila melanogaster. Gene. 263: 31-8. PMID 11223240 DOI: 10.1016/S0378-1119(00)00562-X  0.68
2001 Crabtree JS, Scacheri PC, Ward JM, Garrett-Beal L, Emmert-Buck MR, Edgemon KA, Lorang D, Libutti SK, Chandrasekharappa SC, Marx SJ, Spiegel AM, Collins FS. A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors. Proceedings of the National Academy of Sciences of the United States of America. 98: 1118-23. PMID 11158604 DOI: 10.1073/pnas.98.3.1118  0.68
2001 Alavi A, Chamberlain J, Cherrington AD, Convit A, Craft S, Cryer PE, Davis SN, Davison S, De Leon M, DeRosa M, Drucker D, Albert M, Evans M, Feldman E, Fischbach GD, ... ... Spiegel AM, et al. Workshop on hypoglycemia and the brain Diabetes Technology and Therapeutics. 3: 469-516. DOI: 10.1089/15209150152607259  0.68
2000 Goebel SU, Peghini PL, Goldsmith PK, Spiegel AM, Gibril F, Raffeld M, Jensen RT, Serrano J. Expression of the calcium-sensing receptor in gastrinomas. The Journal of Clinical Endocrinology and Metabolism. 85: 4131-7. PMID 11095444 DOI: 10.1210/jcem.85.11.6963  0.68
2000 Hauache OM, Hu J, Ray K, Xie R, Jacobson KA, Spiegel AM. Effects of a calcimimetic compound and naturally activating mutations on the human Ca2+ receptor and on Ca2+ receptor/metabotropic glutamate chimeric receptors. Endocrinology. 141: 4156-63. PMID 11089548 DOI: 10.1210/endo.141.11.7753  0.68
2000 Hauache OM, Hu J, Ray K, Spiegel AM. Functional interactions between the extracellular domain and the seven-transmembrane domain in Ca2+ receptor activation. Endocrine. 13: 63-70. PMID 11051048 DOI: 10.1385/ENDO:13:1:63  0.68
2000 Knapp JI, Heppner C, Hickman AB, Burns AL, Chandrasekharappa SC, Collins FS, Marx SJ, Spiegel AM, Agarwal SK. Identification and characterization of JunD missense mutants that lack menin binding. Oncogene. 19: 4706-12. PMID 11032020 DOI: 10.1038/sj.onc.1203832  0.68
2000 Spiegel AM. G protein defects in signal transduction. Hormone Research. 53: 17-22. PMID 10971097  0.68
2000 Manickam P, Vogel AM, Agarwal SK, Oda T, Spiegel AM, Marx SJ, Collins FS, Weinstein BM, Chandrasekharappa SC. Isolation, characterization, expression and functional analysis of the zebrafish ortholog of MEN1. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 11: 448-54. PMID 10818209 DOI: 10.1007/s003350010085  0.68
2000 Hu J, Hauache O, Spiegel AM. Human Ca2+ receptor cysteine-rich domain. Analysis of function of mutant and chimeric receptors. The Journal of Biological Chemistry. 275: 16382-9. PMID 10747888 DOI: 10.1074/jbc.M000277200  0.68
2000 Debelenko LV, Swalwell JI, Kelley MJ, Brambilla E, Manickam P, Baibakov G, Agarwal SK, Spiegel AM, Marx SJ, Chandrasekharappa SC, Collins FS, Travis WD, Emmert-Buck MR. MEN1 gene mutation analysis of high-grade neuroendocrine lung carcinoma. Genes, Chromosomes & Cancer. 28: 58-65. PMID 10738303 DOI: 10.1002/(SICI)1098-2264(200005)28:1<58::AID-GCC7>3.0.CO;2-2  0.68
2000 Bianco P, Riminucci M, Majolagbe A, Kuznetsov SA, Collins MT, Mankani MH, Corsi A, Bone HG, Wientroub S, Spiegel AM, Fisher LW, Robey PG. Mutations of the GNAS1 gene, stromal cell dysfunction, and osteomalacic changes in non-McCune-Albright fibrous dysplasia of bone. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 15: 120-8. PMID 10646121 DOI: 10.1359/jbmr.2000.15.1.120  0.68
2000 Goebel SU, Heppner C, Burns AL, Marx SJ, Spiegel AM, Zhuang Z, Lubensky IA, Gibril F, Jensen RT, Serrano J. Genotype/phenotype correlation of multiple endocrine neoplasia type 1 gene mutations in sporadic gastrinomas. The Journal of Clinical Endocrinology and Metabolism. 85: 116-23. PMID 10634374 DOI: 10.1210/jcem.85.1.6260  0.68
1999 Spiegel AM. Hormone resistance caused by mutations in G proteins and G protein-coupled receptors. Journal of Pediatric Endocrinology & Metabolism : Jpem. 12: 303-9. PMID 10698594  0.68
1999 Libutti SK, Alexander HR, Bartlett DL, Sampson ML, Ruddel ME, Skarulis M, Marx SJ, Spiegel AM, Simmonds W, Remaley AT. Kinetic analysis of the rapid intraoperative parathyroid hormone assay in patients during operation for hyperparathyroidism. Surgery. 126: 1145-50; discussion . PMID 10598200 DOI: 10.1067/msy.2099.101835  0.68
1999 Kim YS, Burns AL, Goldsmith PK, Heppner C, Park SY, Chandrasekharappa SC, Collins FS, Spiegel AM, Marx SJ. Stable overexpression of MEN1 suppresses tumorigenicity of RAS. Oncogene. 18: 5936-42. PMID 10557080 DOI: 10.1038/sj.onc.1203005  0.68
1999 Marx SJ, Agarwal SK, Kester MB, Heppner C, Kim YS, Skarulis MC, James LA, Goldsmith PK, Saggar SK, Park SY, Spiegel AM, Burns AL, Debelenko LV, Zhuang Z, Lubensky IA, et al. Multiple endocrine neoplasia type 1: clinical and genetic features of the hereditary endocrine neoplasias. Recent Progress in Hormone Research. 54: 397-438; discussion . PMID 10548885  0.68
1999 Vortmeyer AO, Lubensky IA, Skarulis M, Li G, Moon YW, Park WS, Weil R, Barlow C, Spiegel AM, Marx SJ, Zhuang Z. Multiple endocrine neoplasia type 1: atypical presentation, clinical course, and genetic analysis of multiple tumors. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 12: 919-24. PMID 10496602  0.68
1999 Ray K, Hauschild BC, Steinbach PJ, Goldsmith PK, Hauache O, Spiegel AM. Identification of the cysteine residues in the amino-terminal extracellular domain of the human Ca(2+) receptor critical for dimerization. Implications for function of monomeric Ca(2+) receptor. The Journal of Biological Chemistry. 274: 27642-50. PMID 10488104 DOI: 10.1074/jbc.274.39.27642  0.68
1999 Spiegel AM. Citation for the 1999 Monsanto Clinical Investigator Lecture Award of the Endocrine Society to Dr. Stephen J. Marx. Endocrine Reviews. 20: 590-1. PMID 10453362  0.68
1999 Marx SJ, Agarwal SK, Heppner C, Kim YS, Kester MB, Goldsmith PK, Skarulis MC, Spiegel AM, Burns AL, Debelenko LV, Zhuang Z, Lubensky IA, Liotta LA, Emmert-Buck MR, Guru SC, et al. The gene for multiple endocrine neoplasia type 1: recent findings. Bone. 25: 119-22. PMID 10423035 DOI: 10.1016/S8756-3282(99)00112-X  0.68
1999 Riminucci M, Liu B, Corsi A, Shenker A, Spiegel AM, Robey PG, Bianco P. The histopathology of fibrous dysplasia of bone in patients with activating mutations of the Gs alpha gene: site-specific patterns and recurrent histological hallmarks. The Journal of Pathology. 187: 249-58. PMID 10365102 DOI: 10.1002/(SICI)1096-9896(199901)187:2<249::AID-PATH222>3.0.CO;2-J  0.68
1999 Guru SC, Crabtree JS, Brown KD, Dunn KJ, Manickam P, Prasad NB, Wangsa D, Burns AL, Spiegel AM, Marx SJ, Pavan WJ, Collins FS, Chandrasekharappa SC. Isolation, genomic organization, and expression analysis of Men1, the murine homolog of the MEN1 gene. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 10: 592-6. PMID 10341092 DOI: 10.1007/s003359901051  0.68
1999 Zhao XM, Hauache O, Goldsmith PK, Collins R, Spiegel AM. A missense mutation in the seventh transmembrane domain constitutively activates the human Ca2+ receptor. Febs Letters. 448: 180-4. PMID 10217436 DOI: 10.1016/S0014-5793(99)00368-3  0.68
1999 Goldsmith PK, Fan GF, Ray K, Shiloach J, McPhie P, Rogers KV, Spiegel AM. Expression, purification, and biochemical characterization of the amino-terminal extracellular domain of the human calcium receptor. The Journal of Biological Chemistry. 274: 11303-9. PMID 10196220 DOI: 10.1074/jbc.274.16.11303  0.68
1999 Berger AC, Libutti SK, Bartlett DL, Skarulis MG, Marx SJ, Spiegel AM, Doppman JL, Alexander HR. Heterogeneous gland size in sporadic multiple gland parathyroid hyperplasia. Journal of the American College of Surgeons. 188: 382-9. PMID 10195722 DOI: 10.1016/S1072-7515(98)00317-2  0.68
1999 Agarwal SK, Guru SC, Heppner C, Erdos MR, Collins RM, Park SY, Saggar S, Chandrasekharappa SC, Collins FS, Spiegel AM, Marx SJ, Burns AL. Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription. Cell. 96: 143-52. PMID 9989505 DOI: 10.1016/S0092-8674(00)80967-8  0.68
1999 Heppner C, Reincke M, Agarwal SK, Mora P, Allolio B, Burns AL, Spiegel AM, Marx SJ. MEN1 gene analysis in sporadic adrenocortical neoplasms. The Journal of Clinical Endocrinology and Metabolism. 84: 216-9. PMID 9920087 DOI: 10.1210/jcem.84.1.5388  0.68
1998 Ray K, Clapp P, Goldsmith PK, Spiegel AM. Identification of the sites of N-linked glycosylation on the human calcium receptor and assessment of their role in cell surface expression and signal transduction. The Journal of Biological Chemistry. 273: 34558-67. PMID 9852126 DOI: 10.1074/jbc.273.51.34558  0.68
1998 Fan GF, Ray K, Zhao XM, Goldsmith PK, Spiegel AM. Mutational analysis of the cysteines in the extracellular domain of the human Ca2+ receptor: effects on cell surface expression, dimerization and signal transduction. Febs Letters. 436: 353-6. PMID 9801147 DOI: 10.1016/S0014-5793(98)01165-X  0.68
1998 Marx S, Spiegel AM, Skarulis MC, Doppman JL, Collins FS, Liotta LA. Multiple endocrine neoplasia type 1: clinical and genetic topics. Annals of Internal Medicine. 129: 484-94. PMID 9735087  0.68
1998 Marx SJ, Agarwal SK, Kester MB, Heppner C, Kim YS, Emmert-Buck MR, Debelenko LV, Lubensky IA, Zhuang Z, Guru SC, Manickam P, Olufemi SE, Skarulis MC, Doppman JL, Alexander RH, ... ... Spiegel AM, et al. Germline and somatic mutation of the gene for multiple endocrine neoplasia type 1 (MEN1). Journal of Internal Medicine. 243: 447-53. PMID 9681842 DOI: 10.1046/j.1365-2796.1998.00348.x  0.68
1998 Guru SC, Manickam P, Crabtree JS, Olufemi SE, Agarwal SK, Debelenko LV, Zhuang Z, Lubensky IA, Kester MB, Kim YS, Heppner C, Weisemann JM, Boguski MS, Wang Y, Roe BA, ... ... Spiegel AM, et al. Identification and characterization of the multiple endocrine neoplasia type 1 (MEN1) gene Journal of Internal Medicine. 243: 433-439. PMID 9681840 DOI: 10.1046/j.1365-2796.1998.00346.x  0.68
1998 Agarwal SK, Debelenko LV, Kester MB, Guru SC, Manickam P, Olufemi SE, Skarulis MC, Heppner C, Crabtree JS, Lubensky IA, Zhuang Z, Kim YS, Chandrasekharappa SC, Collins FS, Liotta LA, ... Spiegel AM, et al. Analysis of recurrent germline mutations in the MEN1 gene encountered in apparently unrelated families. Human Mutation. 12: 75-82. PMID 9671267 DOI: 10.1002/(SICI)1098-1004(1998)12:2<75::AID-HUMU1>3.0.CO;2-T  0.68
1998 Doppman JL, Skarulis MC, Chang R, Alexander HR, Bartlett D, Libutti SK, Marx SJ, Spiegel AM. Hypocalcemic stimulation and nonselective venous sampling for localizing parathyroid adenomas: work in progress. Radiology. 208: 145-51. PMID 9646806 DOI: 10.1148/radiology.208.1.9646806  0.68
1998 Emmert-Buck MR, Debelenko LV, Agarwal S, Kester MB, Manickam P, Zhuang Z, Guru SC, Olufemi SE, Burns AL, Chandrasekharappa SC, Lubensky IA, Liotta LA, Skarulis MC, Spiegel AM, Marx SJ, et al. 11q13 allelotype analysis in 27 northern American MEN1 kindreds identifies two distinct founder chromosomes. Molecular Genetics and Metabolism. 63: 151-5. PMID 9562970 DOI: 10.1006/mgme.1997.2649  0.68
1998 Olufemi SE, Green JS, Manickam P, Guru SC, Agarwal SK, Kester MB, Dong Q, Burns AL, Spiegel AM, Marx SJ, Collins FS, Chandrasekharappa SC. Common ancestral mutation in the MEN1 gene is likely responsible for the prolactinoma variant of MEN1 (MEN1Burin) in four kindreds from Newfoundland. Human Mutation. 11: 264-9. PMID 9554741 DOI: 10.1002/(SICI)1098-1004(1998)11:4<264::AID-HUMU2>3.0.CO;2-V  0.68
1998 Collins MT, Skarulis MC, Bilezikian JP, Silverberg SJ, Spiegel AM, Marx SJ. Treatment of hypercalcemia secondary to parathyroid carcinoma with a novel calcimimetic agent. The Journal of Clinical Endocrinology and Metabolism. 83: 1083-8. PMID 9543122 DOI: 10.1210/jcem.83.4.4726  0.68
1998 Bianco P, Kuznetsov SA, Riminucci M, Fisher LW, Spiegel AM, Robey PG. Reproduction of human fibrous dysplasia of bone in immunocompromised mice by transplanted mosaics of normal and Gsalpha-mutated skeletal progenitor cells. The Journal of Clinical Investigation. 101: 1737-44. PMID 9541505 DOI: 10.1172/JCI2361  0.68
1998 Guru SC, Goldsmith PK, Burns AL, Marx SJ, Spiegel AM, Collins FS, Chandrasekharappa SC. Menin, the product of the MEN1 gene, is a nuclear protein. Proceedings of the National Academy of Sciences of the United States of America. 95: 1630-4. PMID 9465067 DOI: 10.1073/pnas.95.4.1630  0.68
1997 Rodriguez-Pena MS, Collins R, Woodard C, Spiegel AM. Decreased insulin content and secretion in RIN 1046-38 cells overexpressing alpha 2-adrenergic receptors. Endocrine. 7: 255-60. PMID 9549052  0.68
1997 Libutti SK, Bartlett DL, jaskowiak NT, Skarulis M, Marx SJ, Spiegel AM, Fraker DL, Doppman JL, Shawker TJ, Alexander HR. The role of thyroid resection during reoperation for persistent or recurrent hyperparathyroidism. Surgery. 122: 1183-7; discussion 1. PMID 9426436 DOI: 10.1016/S0039-6060(97)90225-7  0.68
1997 Zhuang Z, Ezzat SZ, Vortmeyer AO, Weil R, Oldfield EH, Park WS, Pack S, Huang S, Agarwal SK, Guru SC, Manickam P, Debelenko LV, Kester MB, Olufemi SE, Heppner C, ... ... Spiegel AM, et al. Mutations of the MEN1 tumor suppressor gene in pituitary tumors. Cancer Research. 57: 5446-51. PMID 9407947  0.68
1997 Riminucci M, Fisher LW, Shenker A, Spiegel AM, Bianco P, Gehron Robey P. Fibrous dysplasia of bone in the McCune-Albright syndrome: abnormalities in bone formation. The American Journal of Pathology. 151: 1587-600. PMID 9403710  0.68
1997 Ray K, Fan GF, Goldsmith PK, Spiegel AM. The carboxyl terminus of the human calcium receptor. Requirements for cell-surface expression and signal transduction. The Journal of Biological Chemistry. 272: 31355-61. PMID 9395465 DOI: 10.1074/jbc.272.50.31355  0.68
1997 Manickam P, Guru SC, Debelenko LV, Agarwal SK, Olufemi SE, Weisemann JM, Boguski MS, Crabtree JS, Wang Y, Roe BA, Lubensky IA, Zhuang Z, Kester MB, Burns AL, Spiegel AM, et al. Eighteen new polymorphic markers in the multiple endocrine neoplasia type 1 (MEN1) region. Human Genetics. 101: 102-8. PMID 9385379 DOI: 10.1007/s004390050595  0.68
1997 Goldsmith PK, Fan G, Miller JL, Rogers KV, Spiegel AM. Monoclonal antibodies against synthetic peptides corresponding to the extracellular domain of the human Ca2+ receptor: characterization and use in studying concanavalin A inhibition. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 12: 1780-8. PMID 9383682 DOI: 10.1359/jbmr.1997.12.11.1780  0.68
1997 Debelenko LV, Brambilla E, Agarwal SK, Swalwell JI, Kester MB, Lubensky IA, Zhuang Z, Guru SC, Manickam P, Olufemi SE, Chandrasekharappa SC, Crabtree JS, Kim YS, Heppner C, Burns AL, ... Spiegel AM, et al. Identification of MEN1 gene mutations in sporadic carcinoid tumors of the lung. Human Molecular Genetics. 6: 2285-90. PMID 9361035  0.68
1997 Zhuang Z, Vortmeyer AO, Pack S, Huang S, Pham TA, Wang C, Park WS, Agarwal SK, Debelenko LV, Kester M, Guru SC, Manickam P, Olufemi SE, Yu F, Heppner C, ... ... Spiegel AM, et al. Somatic mutations of the MEN1 tumor suppressor gene in sporadic gastrinomas and insulinomas. Cancer Research. 57: 4682-6. PMID 9354421  0.68
1997 Spiegel AM. Citation for the 1997 Gerald D. Aurbach Lecture Award of The Endocrine Society to Edward M. Brown. Endocrine Reviews. 18: 616-7. PMID 9267769  0.68
1997 Guru SC, Agarwal SK, Manickam P, Olufemi SE, Crabtree JS, Weisemann JM, Kester MB, Kim YS, Wang Y, Emmert-Buck MR, Liotta LA, Spiegel AM, Boguski MS, Roe BA, Collins FS, et al. A transcript map for the 2.8-Mb region containing the multiple endocrine neoplasia type 1 locus. Genome Research. 7: 725-35. PMID 9253601  0.68
1997 De Luca F, Ray K, Mancilla EE, Fan GF, Winer KK, Gore P, Spiegel AM, Baron J. Sporadic hypoparathyroidism caused by de Novo gain-of-function mutations of the Ca(2+)-sensing receptor. The Journal of Clinical Endocrinology and Metabolism. 82: 2710-5. PMID 9253358 DOI: 10.1210/jcem.82.8.4166  0.68
1997 Heppner C, Kester MB, Agarwal SK, Debelenko LV, Emmert-Buck MR, Guru SC, Manickam P, Olufemi SE, Skarulis MC, Doppman JL, Alexander RH, Kim YS, Saggar SK, Lubensky IA, Zhuang Z, ... ... Spiegel AM, et al. Somatic mutation of the MEN1 gene in parathyroid tumours. Nature Genetics. 16: 375-8. PMID 9241276 DOI: 10.1038/ng0897-375  0.68
1997 Darling TN, Skarulis MC, Steinberg SM, Marx SJ, Spiegel AM, Turner M. Multiple facial angiofibromas and collagenomas in patients with multiple endocrine neoplasia type 1. Archives of Dermatology. 133: 853-7. PMID 9236523  0.68
1997 Agarwal SK, Kester MB, Debelenko LV, Heppner C, Emmert-Buck MR, Skarulis MC, Doppman JL, Kim YS, Lubensky IA, Zhuang Z, Green JS, Guru SC, Manickam P, Olufemi SE, Liotta LA, ... ... Spiegel AM, et al. Germline mutations of the MEN1 gene in familial multiple endocrine neoplasia type 1 and related states. Human Molecular Genetics. 6: 1169-75. PMID 9215689 DOI: 10.1093/hmg/6.7.1169  0.68
1997 Spiegel AM. Inborn errors of signal transduction: mutations in G proteins and G protein-coupled receptors as a cause of disease. Journal of Inherited Metabolic Disease. 20: 113-21. PMID 9211183 DOI: 10.1023/A:1005393501786  0.68
1997 Guru SC, Olufemi SE, Manickam P, Cummings C, Gieser LM, Pike BL, Bittner ML, Jiang Y, Chinault AC, Nowak NJ, Brzozowska A, Crabtree JS, Wang Y, Roe BA, Weisemann JM, ... ... Spiegel AM, et al. A 2.8-Mb clone contig of the multiple endocrine neoplasia type 1 (MEN1) region at 11q13. Genomics. 42: 436-45. PMID 9205115 DOI: 10.1006/geno.1997.4783  0.6
1997 Debelenko LV, Zhuang Z, Emmert-Buck MR, Chandrasekharappa SC, Manickam P, Guru SC, Marx SJ, Skarulis MC, Spiegel AM, Collins FS, Jensen RT, Liotta LA, Lubensky IA. Allelic deletions on chromosome 11q13 in multiple endocrine neoplasia type 1-associated and sporadic gastrinomas and pancreatic endocrine tumors. Cancer Research. 57: 2238-43. PMID 9187127  0.68
1997 Emmert-Buck MR, Lubensky IA, Dong Q, Manickam P, Guru SC, Kester MB, Olufemi SE, Agarwal S, Burns AL, Spiegel AM, Collins FS, Marx SJ, Zhuang Z, Liotta LA, Chandrasekharappa SC, et al. Localization of the multiple endocrine neoplasia type I (MEN1) gene based on tumor loss of heterozygosity analysis. Cancer Research. 57: 1855-8. PMID 9157974  0.68
1997 Dong Q, Debelenko LV, Chandrasekharappa SC, Emmert-Buck MR, Zhuang Z, Guru SC, Manickam P, Skarulis M, Lubensky IA, Liotta LA, Collins FS, Marx SJ, Spiegel AM. Loss of heterozygosity at 11q13: analysis of pituitary tumors, lung carcinoids, lipomas, and other uncommon tumors in subjects with familial multiple endocrine neoplasia type 1. The Journal of Clinical Endocrinology and Metabolism. 82: 1416-20. PMID 9141526 DOI: 10.1210/jcem.82.5.3944  0.68
1997 Fan G, Goldsmith PK, Collins R, Dunn CK, Krapcho KJ, Rogers KV, Spiegel AM. N-linked glycosylation of the human Ca2+ receptor is essential for its expression at the cell surface. Endocrinology. 138: 1916-22. PMID 9112387 DOI: 10.1210/endo.138.5.5131  0.68
1997 Chandrasekharappa SC, Guru SC, Manickam P, Olufemi SE, Collins FS, Emmert-Buck MR, Debelenko LV, Zhuang Z, Lubensky IA, Liotta LA, Crabtree JS, Wang Y, Roe BA, Weisemann J, Boguski MS, ... ... Spiegel AM, et al. Positional cloning of the gene for multiple endocrine neoplasia-type 1. Science (New York, N.Y.). 276: 404-7. PMID 9103196 DOI: 10.1126/science.276.5311.404  0.68
1997 Debelenko LV, Emmert-Buck MR, Manickam P, Kester M, Guru SC, DiFranco EM, Olufemi SE, Agarwal S, Lubensky IA, Zhuang Z, Burns AL, Spiegel AM, Liotta LA, Collins FS, Marx SJ, et al. Haplotype analysis defines a minimal interval for the multiple endocrine neoplasia type 1 (MEN1) gene. Cancer Research. 57: 1039-42. PMID 9067266  0.68
1997 Spiegel AM. The molecular basis of disorders caused by defects in G proteins. Hormone Research. 47: 89-96. PMID 9050946  0.68
1997 Ray K, Fan GF, Goldsmith PK, Spiegel AM. Mutational analysis of the carboxyl-terminal region of the human calcium-sensing receptor Faseb Journal. 11: A1168.  0.68
1997 Rodriguez Penn MS, Woodard C, Collins R, Spiegel A. Decreased insulin content and secretion in rin 1046-38 cells overexpressing α a2-adrenergic receptors Faseb Journal. 11: A1161.  0.68
1996 Wenkert D, Schoneberg T, Merendino JJ, Rodriguez Pena MS, Vinitsky R, Goldsmith PK, Wess J, Spiegel AM. Functional characterization of five V2 vasopressin receptor gene mutations. Molecular and Cellular Endocrinology. 124: 43-50. PMID 9027323 DOI: 10.1016/S0303-7207(96)03926-3  0.68
1996 Lubensky IA, Debelenko LV, Zhuang Z, Emmert-Buck MR, Dong Q, Chandrasekharappa S, Guru SC, Manickam P, Olufemi SE, Marx SJ, Spiegel AM, Collins FS, Liotta LA. Allelic deletions on chromosome 11q13 in multiple tumors from individual MEN1 patients. Cancer Research. 56: 5272-8. PMID 8912868  0.68
1996 Doppman JL, Skarulis MC, Chen CC, Chang R, Pass HI, Fraker DL, Alexander HR, Niederle B, Marx SJ, Norton JA, Wells SA, Spiegel AM. Parathyroid adenomas in the aortopulmonary window. Radiology. 201: 456-62. PMID 8888240 DOI: 10.1148/radiology.201.2.8888240  0.68
1996 Spiegel AM. Defects in G protein-coupled signal transduction in human disease. Annual Review of Physiology. 58: 143-70. PMID 8815789 DOI: 10.1146/annurev.ph.58.030196.001043  0.68
1996 Dong Q, Brucker-Davis F, Weintraub BD, Smallridge RC, Carr FE, Battey J, Spiegel AM, Shenker A. Screening of candidate oncogenes in human thyrotroph tumors: absence of activating mutations of the G alpha q, G alpha 11, G alpha s, or thyrotropin-releasing hormone receptor genes. The Journal of Clinical Endocrinology and Metabolism. 81: 1134-40. PMID 8772588 DOI: 10.1210/jcem.81.3.8772588  0.68
1996 Hermouet S, Aznavoorian S, Spiegel AM. In vitro and in vivo growth inhibition of murine melanoma K-1735 cell by a dominant negative mutant alpha subunit of the Gi2 protein. Cellular Signalling. 8: 159-66. PMID 8736698 DOI: 10.1016/0898-6568(95)02049-7  0.68
1996 Spiegel AM. Mutations in G proteins and G protein-coupled receptors in endocrine disease. The Journal of Clinical Endocrinology and Metabolism. 81: 2434-42. PMID 8675557 DOI: 10.1210/jcem.81.7.8675557  0.68
1996 Wenkert D, Schoneberg T, Merendino JJ, Pena M, Vinitsky R, Goldsmith PK, Wess J, Spiegel AM. Expression and functional characterization of five v2 vasopressin receptor gene mutations identified in families with x-linked nephrogenic diabetes insipidus Journal of Investigative Medicine. 44: 225a.  0.68
1995 Dong Q, Shenker A, Way J, Haddad BR, Lin K, Hughes MR, McBride OW, Spiegel AM, Battey J. Molecular cloning of human G alpha q cDNA and chromosomal localization of the G alpha q gene (GNAQ) and a processed pseudogene. Genomics. 30: 470-75. PMID 8825633 DOI: 10.1006/geno.1995.1267  0.68
1995 Shenker A, Chanson P, Weinstein LS, Chi P, Spiegel AM, Lomri A, Marie PJ. Osteoblastic cells derived from isolated lesions of fibrous dysplasia contain activating somatic mutations of the Gs alpha gene. Human Molecular Genetics. 4: 1675-6. PMID 8541861  0.68
1995 Chen CC, Skarulis MC, Fraker DL, Alexander R, Marx SJ, Spiegel AM. Technetium-99m-sestamibi imaging before reoperation for primary hyperparathyroidism. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 36: 2186-91. PMID 8523102  0.68
1995 Chen CC, Premkumar A, Hill SC, Skarulis MC, Spiegel AM. Tc-99m sestamibi imaging of a hyperfunctioning parathyroid autograft with Doppler ultrasound and MRI correlation. Clinical Nuclear Medicine. 20: 222-5. PMID 7750215 DOI: 10.1097/00003072-199503000-00007  0.68
1995 Varrault A, Pena MS, Goldsmith PK, Mithal A, Brown EM, Spiegel AM. Expression of G protein alpha-subunits in bovine parathyroid. Endocrinology. 136: 4390-6. PMID 7664659 DOI: 10.1210/endo.136.10.7664659  0.68
1995 Spiegel AM. G protein gene knockout hits the gut. Nature Medicine. 1: 522-4. PMID 7585115 DOI: 10.1038/nm0695-522  0.68
1995 Buell JF, Fraker DL, Doppman JL, Shawker TH, Skarulis MC, Spiegel AM, Marx SJ, Alexander HR. High cervical intravagal hypercellular parathyroid gland as the etiology of severe persistent primary hyperparathyroidism. The American Surgeon. 61: 943-6. PMID 7486421  0.68
1994 Doppman JL, Shawker TH, Fraker DL, Alexander HR, Skarulis MC, Lack EE, Spiegel AM. Parathyroid adenoma within the vagus nerve. Ajr. American Journal of Roentgenology. 163: 943-5. PMID 8092040 DOI: 10.2214/ajr.163.4.8092040  0.68
1994 Shenker A, Weinstein LS, Sweet DE, Spiegel AM. An activating Gs alpha mutation is present in fibrous dysplasia of bone in the McCune-Albright syndrome. The Journal of Clinical Endocrinology and Metabolism. 79: 750-5. PMID 8077356 DOI: 10.1210/jcem.79.3.8077356  0.68
1994 Degtyarev MY, Spiegel AM, Jones TL. The membrane localization of the G protein alpha s subunit is not dependent on its TENIR sequence or effector domain. Cellular Signalling. 6: 25-33. PMID 8011426 DOI: 10.1016/0898-6568(94)90058-2  0.68
1994 Abou-Samra AB, Goldsmith PK, Xie LY, Jüppner H, Spiegel AM, Segre GV. Down-regulation of parathyroid (PTH)/PTH-related peptide receptor immunoreactivity and PTH binding in opossum kidney cells by PTH and dexamethasone. Endocrinology. 135: 2588-94. PMID 7988447 DOI: 10.1210/endo.135.6.7988447  0.68
1994 Wenkert D, Merendino JJ, Shenker A, Thambi N, Robertson GL, Moses AM, Spiegel AM. Novel mutations in the V2 vasopressin receptor gene of patients with X-linked nephrogenic diabetes insipidus. Human Molecular Genetics. 3: 1429-30. PMID 7987330  0.68
1994 Billingsley KG, Fraker DL, Doppman JL, Norton JA, Shawker TH, Skarulis MC, Marx SJ, Spiegel AM, Alexander HR. Localization and operative management of undescended parathyroid adenomas in patients with persistent primary hyperparathyroidism. Surgery. 116: 982-9; discussion 98. PMID 7985106  0.68
1994 MacFarlane MP, Fraker DL, Shawker TH, Norton JA, Doppman JL, Chang RA, Skarulis MC, Marx SJ, Spiegel AM, Alexander HR. Use of preoperative fine-needle aspiration in patients undergoing reoperation for primary hyperparathyroidism. Surgery. 116: 959-64; discussion 9. PMID 7985103  0.68
1994 Degtyarev MY, Spiegel AM, Jones TL. Palmitoylation of a G protein alpha i subunit requires membrane localization not myristoylation. The Journal of Biological Chemistry. 269: 30898-903. PMID 7983022  0.68
1993 Merendino JJ, Speigel AM, Crawford JD, O'Carroll AM, Brownstein MJ, Lolait SJ. Brief report: a mutation in the vasopressin V2-receptor gene in a kindred with X-linked nephrogenic diabetes insipidus. The New England Journal of Medicine. 328: 1538-41. PMID 8479491 DOI: 10.1056/NEJM199305273282106  0.68
1993 Pamukcu R, Spiegel AM, Chang EB. Biochemical and immunochemical localization of GTP-binding proteins in the rat ileal enterocyte. The Journal of Laboratory and Clinical Medicine. 121: 689-96. PMID 8478596  0.68
1993 LaMorte VJ, Harootunian AT, Spiegel AM, Tsien RY, Feramisco JR. Mediation of growth factor induced DNA synthesis and calcium mobilization by Gq and Gi2. The Journal of Cell Biology. 121: 91-9. PMID 8458876  0.68
1993 Jones TL, Woodard C, Spiegel AM. Baculovirus expression and purification of a soluble, mutant G-protein alpha subunit. Protein Expression and Purification. 4: 64-71. PMID 8425110 DOI: 10.1006/prep.1993.1010  0.68
1993 Dohlman HG, Goldsmith P, Spiegel AM, Thorner J. Pheromone action regulates G-protein alpha-subunit myristoylation in the yeast Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 90: 9688-92. PMID 8415763  0.68
1993 Shenker A, Weinstein LS, Moran A, Pescovitz OH, Charest NJ, Boney CM, Van Wyk JJ, Merino MJ, Feuillan PP, Spiegel AM. Severe endocrine and nonendocrine manifestations of the McCune-Albright syndrome associated with activating mutations of stimulatory G protein GS. The Journal of Pediatrics. 123: 509-18. PMID 8410501 DOI: 10.1016/S0022-3476(05)80943-6  0.68
1993 Spiegel AM, Weinstein LS, Shenker A, Hermouet S, Merendino JJ. G proteins: from basic to clinical studies. Advances in Second Messenger and Phosphoprotein Research. 28: 37-46. PMID 8398416  0.68
1993 Spiegel AM, Weinstein LS, Shenker A. Abnormalities in G protein-coupled signal transduction pathways in human disease. The Journal of Clinical Investigation. 92: 1119-25. PMID 8397218 DOI: 10.1172/JCI116680  0.68
1993 Hermouet S, de Mazancourt P, Spiegel AM. Mitogenic effects of pertussis toxin-sensitive G-protein alpha subunits: the mitogenic action of alpha i2 in NIH 3T3 cells is mimicked by alpha i1, but not alpha i3. Cellular Signalling. 5: 215-25. PMID 8388703 DOI: 10.1016/0898-6568(93)90072-T  0.68
1993 Hermouet S, Murakami T, Spiegel AM. Stable changes in expression or activation of G protein alpha i or alpha q subunits affect the expression of both beta 1 and beta 2 subunits. Febs Letters. 327: 183-8. PMID 8335108 DOI: 10.1016/0014-5793(93)80166-R  0.68
1993 Sugg SL, Fraker DL, Alexander R, Doppman JL, Miller DL, Chang R, Skarulis MC, Marx SJ, Spiegel AM, Norton JA. Prospective evaluation of selective venous sampling for parathyroid hormone concentration in patients undergoing reoperations for primary hyperparathyroidism. Surgery. 114: 1004-9; discussion 1. PMID 8256203  0.68
1993 Degtyarev MY, Spiegel AM, Jones TL. Increased palmitoylation of the Gs protein alpha subunit after activation by the beta-adrenergic receptor or cholera toxin. The Journal of Biological Chemistry. 268: 23769-72. PMID 8226908  0.68
1993 Spiegel AM. Gerald D. Aurbach, 1927-1991 Vitamins and Hormones. 47: xi-xii. DOI: 10.1016/S0083-6729(08)60443-4  0.68
1992 Spiegel AM. Heterotrimeric GTP-binding proteins: an expanding family of signal transducers. Medicinal Research Reviews. 12: 55-71. PMID 1738245  0.68
1992 LaMorte VJ, Goldsmith PK, Spiegel AM, Meinkoth JL, Feramisco JR. Inhibition of DNA synthesis in living cells by microinjection of Gi2 antibodies. The Journal of Biological Chemistry. 267: 691-4. PMID 1730660  0.68
1992 Streeten EA, Weinstein LS, Norton JA, Mulvihill JJ, White BJ, Friedman E, Jaffe G, Brandi ML, Stewart K, Zimering MB. Studies in a kindred with parathyroid carcinoma. The Journal of Clinical Endocrinology and Metabolism. 75: 362-6. PMID 1639936 DOI: 10.1210/jcem.75.2.1639936  0.68
1992 Murakami T, Simonds WF, Spiegel AM. Site-specific antibodies directed against G protein beta and gamma subunits: effects on alpha and beta gamma subunit interaction. Biochemistry. 31: 2905-11. PMID 1550816  0.68
1992 Doherty GM, Doppman JL, Miller DL, Gee MS, Marx SJ, Spiegel AM, Aurbach GD, Pass HI, Brennan MF, Norton JA. Results of a multidisciplinary strategy for management of mediastinal parathyroid adenoma as a cause of persistent primary hyperparathyroidism. Annals of Surgery. 215: 101-6. PMID 1546895  0.68
1992 Butrynski JE, Jones TL, Backlund PS, Spiegel AM. Differential isoprenylation of carboxy-terminal mutants of an inhibitory G-protein alpha-subunit: neither farnesylation nor geranylgeranylation is sufficient for membrane attachment. Biochemistry. 31: 8030-5. PMID 1510988  0.68
1992 Weinstein LS, Gejman PV, de Mazancourt P, American N, Spiegel AM. A heterozygous 4-bp deletion mutation in the Gs alpha gene (GNAS1) in a patient with Albright hereditary osteodystrophy. Genomics. 13: 1319-21. PMID 1505964 DOI: 10.1016/0888-7543(92)90056-X  0.68
1992 Spiegel AM. Role of G proteins in signal transduction. Clinical Neuropharmacology. 15: 200A-201A. PMID 1498810  0.68
1992 Potts JT, Spiegel AM. In memoriam Gerald D. Aurbach. Molecular Endocrinology (Baltimore, Md.). 6: 1982-4. PMID 1480184 DOI: 10.1210/mend.6.11.1480184  0.68
1992 Potts JT, Spiegel AM. In memoriam Gerald D. Aurbach. The Journal of Clinical Endocrinology and Metabolism. 75: 1386-8. PMID 1430101 DOI: 10.1210/jcem.75.5.1430101  0.68
1992 Spiegel AM, Shenker A, Weinstein LS. Receptor-effector coupling by G proteins: implications for normal and abnormal signal transduction. Endocrine Reviews. 13: 536-65. PMID 1425488 DOI: 10.1210/edrv-13-3-536  0.68
1992 Juhnn YS, Jones TL, Spiegel AM. Amino- and carboxy-terminal deletion mutants of Gs alpha are localized to the particulate fraction of transfected COS cells. The Journal of Cell Biology. 119: 523-30. PMID 1400589  0.68
1992 Meinkoth JL, Goldsmith PK, Spiegel AM, Feramisco JR, Burrow GN. Inhibition of thyrotropin-induced DNA synthesis in thyroid follicular cells by microinjection of an antibody to the stimulatory G protein of adenylate cyclase, Gs. The Journal of Biological Chemistry. 267: 13239-45. PMID 1377681  0.68
1992 Friedman E, De Marco L, Gejman PV, Norton JA, Bale AE, Aurbach GD, Spiegel AM, Marx SJ. Allelic loss from chromosome 11 in parathyroid tumors. Cancer Research. 52: 6804-9. PMID 1360870  0.68
1992 Hermouet S, de Mazancourt P, Spiegel AM, Farquhar MG, Wilson BS. High level expression of transfected G protein alpha i3 subunit is required for plasma membrane targeting and adenylyl cyclase inhibition in NIH 3T3 fibroblasts. Febs Letters. 312: 223-8. PMID 1330693 DOI: 10.1016/0014-5793(92)80940-I  0.68
1992 Spiegel AM. G proteins in cellular control. Current Opinion in Cell Biology. 4: 203-11. PMID 1318059  0.68
1992 Chiavaroli C, Cooper DMF, Boyajian CL, Murray-Whelan R, Demaurex N, Spiegel AM, Schlegel W. Spontaneous intracellular calcium oscillations and G(s)α subunit expression are inversely correlated with secretory granule content in pituitary cells Journal of Neuroendocrinology. 4: 473-481.  0.68
1991 Fraker DL, Travis WD, Merendino JJ, Zimering MB, Streeten EA, Weinstein LS, Marx SJ, Spiegel AM, Aurbach GD, Doppman JL. Locally recurrent parathyroid neoplasms as a cause for recurrent and persistent primary hyperparathyroidism. Annals of Surgery. 213: 58-65. PMID 1985539  0.68
1991 Weinstein LS, Shenker A, Gejman PV, Merino MJ, Friedman E, Spiegel AM. Activating mutations of the stimulatory G protein in the McCune-Albright syndrome. The New England Journal of Medicine. 325: 1688-95. PMID 1944469 DOI: 10.1056/NEJM199112123252403  0.68
1991 Shenker A, Goldsmith P, Unson CG, Spiegel AM. The G protein coupled to the thromboxane A2 receptor in human platelets is a member of the novel Gq family. The Journal of Biological Chemistry. 266: 9309-13. PMID 1851174  0.68
1991 Shenker A, Goldsmith P, Unson CG, Spiegel AM. The G protein coupled to the thromboxane A2 receptor in human platelets is a member of the novel Gq family. Transactions of the Association of American Physicians. 104: 11-20. PMID 1845138  0.68
1991 Fargin A, Yamamoto K, Cotecchia S, Goldsmith PK, Spiegel AM, Lapetina EG, Caron MG, Lefkowitz RJ. Dual coupling of the cloned 5-HT1A receptor to both adenylyl cyclase and phospholipase C is mediated via the same Gi protein. Cellular Signalling. 3: 547-57. PMID 1786205 DOI: 10.1016/0898-6568(91)90031-O  0.68
1991 Spiegel AM. Pathophysiology of primary hyperparathyroidism. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 6: S15-7; discussion S3. PMID 1763667 DOI: 10.1002/jbmr.5650061407  0.68
1991 Cormont M, Le Marchand-Brustel Y, Van Obberghen E, Spiegel AM, Sharp GW. Identification of G protein alpha-subunits in RINm5F cells and their selective interaction with galanin receptor. Diabetes. 40: 1170-6. PMID 1718802  0.68
1991 Simonds WF, Butrynski JE, Gautam N, Unson CG, Spiegel AM. G-protein beta gamma dimers. Membrane targeting requires subunit coexpression and intact gamma C-A-A-X domain. The Journal of Biological Chemistry. 266: 5363-6. PMID 1706334  0.68
1991 Marx SJ, Menczel J, Campbell G, Aurbach GD, Spiegel AM, Norton JA. Heterogeneous size of the parathyroid glands in familial multiple endocrine neoplasia type 1. Clinical Endocrinology. 35: 521-6. PMID 1685109  0.68
1991 Bale AE, Norton JA, Wong EL, Fryburg JS, Maton PN, Oldfield EH, Streeten E, Aurbach GD, Brandi ML, Friedman E. Allelic loss on chromosome 11 in hereditary and sporadic tumors related to familial multiple endocrine neoplasia type 1. Cancer Research. 51: 1154-7. PMID 1671755  0.68
1991 Hermouet S, Merendino JJ, Gutkind JS, Spiegel AM. Activating and inactivating mutations of the alpha subunit of Gi2 protein have opposite effects on proliferation of NIH 3T3 cells. Proceedings of the National Academy of Sciences of the United States of America. 88: 10455-9. PMID 1660138  0.68
1991 Hamilton SL, Codina J, Hawkes MJ, Yatani A, Sawada T, Strickland FM, Froehner SC, Spiegel AM, Toro L, Stefani E. Evidence for direct interaction of Gs alpha with the Ca2+ channel of skeletal muscle. The Journal of Biological Chemistry. 266: 19528-35. PMID 1655789  0.68
1991 Bégeot M, Langlois D, Spiegel AM, Saez JM. Regulation of guanine nucleotide binding regulatory proteins in cultured adrenal cells by adrenocorticotropin and angiotensin-II. Endocrinology. 128: 3162-8. PMID 1645263 DOI: 10.1210/endo-128-6-3162  0.68
1990 Friedman E, Bale AE, Marx SJ, Norton JA, Arnold A, Tu T, Aurbach GD, Spiegel AM. Genetic abnormalities in sporadic parathyroid adenomas. The Journal of Clinical Endocrinology and Metabolism. 71: 293-7. PMID 2199477 DOI: 10.1210/jcem-71-2-293  0.68
1988 Darling GE, Marx SJ, Spiegel AM, Aurbach GD, Norton JA. Prospective analysis of intraoperative and postoperative urinary cyclic adenosine 3',5'-monophosphate levels to predict outcome of patients undergoing reoperations for primary hyperparathyroidism. Surgery. 104: 1128-36. PMID 2848325  0.68
1987 Miller DL, Doppman JL, Chang R, Simmons JT, O'Leary TJ, Norton JA, Spiegel AM, Marx SJ, Aurbach GD. Angiographic ablation of parathyroid adenomas: lessons from a 10-year experience. Radiology. 165: 601-7. PMID 3685340 DOI: 10.1148/radiology.165.3.3685340  0.68
1987 Miller DL, Doppman JL, Krudy AG, Shawker TH, Norton JA, Vucich JJ, Morrish KA, Marx SJ, Spiegel AM, Aurbach GD. Localization of parathyroid adenomas in patients who have undergone surgery. Part II. Invasive procedures. Radiology. 162: 138-41. PMID 3538146 DOI: 10.1148/radiology.162.1.3538146  0.68
1987 Miller DL, Doppman JL, Shawker TH, Krudy AG, Norton JA, Vucich JJ, Morrish KA, Marx SJ, Spiegel AM, Aurbach GD. Localization of parathyroid adenomas in patients who have undergone surgery. Part I. Noninvasive imaging methods. Radiology. 162: 133-7. PMID 3538145 DOI: 10.1148/radiology.162.1.3538145  0.68
1987 Kern KA, Shawker TH, Doppman JL, Miller DL, Marx SJ, Spiegel AM, Aurbach GD, Norton JA. The use of high-resolution ultrasound to locate parathyroid tumors during reoperations for primary hyperparathyroidism. World Journal of Surgery. 11: 579-85. PMID 3314177 DOI: 10.1007/BF01655831  0.68
1986 Norton JA, Shawker TH, Jones BL, Spiegel AM, Marx SJ, Fitzpatrick L, Aurbach GD, Doppman JL. Intraoperative ultrasound and reoperative parathyroid surgery: an initial evaluation. World Journal of Surgery. 10: 631-9. PMID 3529650 DOI: 10.1007/BF01655542  0.68
1986 Brandi ML, Aurbach GD, Fitzpatrick LA, Quarto R, Spiegel AM, Bliziotes MM, Norton JA, Doppman JL, Marx SJ. Parathyroid mitogenic activity in plasma from patients with familial multiple endocrine neoplasia type 1. The New England Journal of Medicine. 314: 1287-93. PMID 2871488 DOI: 10.1056/NEJM198605153142004  0.68
1985 Skibber JM, Reynolds JC, Spiegel AM, Marx SJ, Fitzpatrick LA, Aurbach GD, Wesley RA, Norton JA. Computerized technetium/thallium scans and parathyroid reoperation. Surgery. 98: 1077-82. PMID 3906975  0.68
1985 Doppman JL, Shawker TH, Krudy AG, Miller DL, Marx SJ, Spiegel AM, Norton JA, Brennan MF, Schaaf M, Aurbach GD. Parathymic parathyroid: CT, US, and angiographic findings. Radiology. 157: 419-23. PMID 3901107 DOI: 10.1148/radiology.157.2.3901107  0.68
1984 Krudy AG, Doppman JL, Marx SJ, Norton JA, Spiegel AM, Santora AC, Aurbach GD. Parathyroid aspiration directed by angiography: an alternative to venous sampling. Radiology. 152: 207-8. PMID 6729114 DOI: 10.1148/radiology.152.1.6729114  0.68
1984 Krudy AG, Doppman JL, Miller DL, Norton JA, Marx SJ, Spiegel AM, Santora AC, Aurbach GD, Schaaf M. Detection of mediastinal parathyroid glands by nonselective digital arteriography. Ajr. American Journal of Roentgenology. 142: 693-5. PMID 6608224 DOI: 10.2214/ajr.142.4.693  0.68
1983 Doppman JL, Krudy AG, Marx SJ, Saxe A, Schneider P, Norton JA, Spiegel AM, Downs RW, Schaaf M, Brennan ME, Schneider AB, Aurbach GD. Aspiration of enlarged parathyroid glands for parathyroid hormone assay. Radiology. 148: 31-5. PMID 6856859 DOI: 10.1148/radiology.148.1.6856859  0.68
1983 Levine MA, Downs RW, Moses AM, Breslau NA, Marx SJ, Lasker RD, Rizzoli RE, Aurbach GD, Spiegel AM. Resistance to multiple hormones in patients with pseudohypoparathyroidism. Association with deficient activity of guanine nucleotide regulatory protein. The American Journal of Medicine. 74: 545-56. PMID 6301273 DOI: 10.1016/0002-9343(83)91008-2  0.68
1983 Krudy AG, Doppman JL, Miller DL, Marx SJ, Norton JA, Santora AC, Lasker RD, Downs RW, Spiegel AM, Aurbach GD. Work in progress: abnormal parathyroid glands. Comparison of nonselective arterial digital arteriography, selective parathyroid arteriography, and venous digital arteriography as methods of detection. Radiology. 148: 23-9. PMID 6134300 DOI: 10.1148/radiology.148.1.6134300  0.68
1982 Brennan MF, Doppman JL, Kurdy AG, Marx SJ, Spiegel AM, Aurbach GD. Assessment of techniques for preoperative parathyroid gland localization in patients undergoing reoperation for hyperparathyroidism. Surgery. 91: 6-11. PMID 7054909  0.68
1982 Marx SJ, Spiegel AM, Levine MA, Rizzoli RE, Lasker RD, Santora AC, Downs RW, Aurbach GD. Familial hypocalciuric hypercalcemia: the relation to primary parathyroid hyperplasia. The New England Journal of Medicine. 307: 416-26. PMID 7045673 DOI: 10.1056/NEJM198208123070707  0.68
1982 Spiegel AM, Levine MA, Marx SJ, Aurbach GD. Pseudohypoparathyroidism: the molecular basis for hormone resistance--a retrospective. The New England Journal of Medicine. 307: 679-81. PMID 6287258 DOI: 10.1056/NEJM198209093071111  0.68
1982 Spiegel AM, Levine MA, Aurbach GD, Downs RW, Marx SJ, Lasker RD, Moses AM, Breslau NA. Deficiency of hormone receptor-adenylate cyclase coupling protein: basis for hormone resistance in pseudohypoparathyroidism. The American Journal of Physiology. 243: E37-42. PMID 6283911  0.68
1982 Krawietz W, Downs RW, Spiegel AM, Aurbach GD. Vanadate stimulates adenylate cyclase via the guanine nucleotide regulatory protein by a mechanism differing from that of fluoride. Biochemical Pharmacology. 31: 843-8. PMID 6282277 DOI: 10.1016/0006-2952(82)90472-5  0.68
1982 Stock JL, Weintraub BD, Rosen SW, Aurbach GD, Spiegel AM, Marx SJ. Human chorionic gonadotropin subunit measurement in primary hyperparathyroidism. The Journal of Clinical Endocrinology and Metabolism. 54: 57-63. PMID 6274898 DOI: 10.1210/jcem-54-1-57  0.68
1981 Spiegel AM, Downs RW, Levine MA, Singer MJ, Krawietz W, Marx SJ, Woodard CJ, Reen SA, Aurbach GD. The role of guanine nucleotides in regulation of adenylate cyclase activity. Recent Progress in Hormone Research. 37: 635-65. PMID 7280358  0.68
1981 Krudy AG, Doppman JL, Brennan MF, Marx SJ, Spiegel AM, Stock JL, Aurbach GD. The detection of mediastinal parathyroid glands by computed tomography, selective arteriography, and venous sampling: an analysis of 17 cases. Radiology. 140: 739-44. PMID 7280244 DOI: 10.1148/radiology.140.3.7280244  0.68
1981 Stock JL, Krudy AG, Doppman JL, Jones AE, Brennan MF, Attie MF, Downs RW, Levine MA, Marx SJ, Spiegel AM, Aurbach GD. Parathyroid imaging after intraarterial injections of [75Se]selenomethionine. The Journal of Clinical Endocrinology and Metabolism. 52: 835-9. PMID 7228990 DOI: 10.1210/jcem-52-5-835  0.68
1981 Spiegel AM, Marx SJ, Brennan MF, Brown EM, Downs RW, Gardner DG, Attie MF, Aurbach GD. Parathyroid function after parathyroidectomy: evaluation by measurement of urinary cAMP. Clinical Endocrinology. 15: 65-73. PMID 6273023  0.68
1981 Downs RW, Reen SA, Levine MA, Aurbach GD, Spiegel AM. Cholera-toxin-dependent ADP-ribosylation of the adenylate cyclase regulatory protein in turkey erythrocyte membranes. Archives of Biochemistry and Biophysics. 209: 284-90. PMID 6269497 DOI: 10.1016/0003-9861(81)90282-4  0.68
1980 Attie MF, Brown EM, Gardner DG, Spiegel AM, Aurbach GD. Characterization of the dopamine-responsive adenylate cyclase of bovine parathyroid cells and its relationship to parathyroid hormone secretion. Endocrinology. 107: 1776-81. PMID 7428692 DOI: 10.1210/endo-107-6-1776  0.68
1980 Marx SJ, Aurbach GD, Spiegel AM. Incidence of primary hyperparathyroidism. The New England Journal of Medicine. 302: 1313. PMID 7366701  0.68
1980 Marx SJ, Spiegel AM, Brown EM, Downs RW, Attie MF, Stock JL, Levine MA, Aurbach GD. Urinary cyclic 3',5'-adenosine monophosphate (cAMP): an index of the action of parathyroid hormone on the kidney. Progress in Biochemical Pharmacology. 17: 182-9. PMID 6259655  0.68
1980 Spiegel AM, Eastman ST, Attie MF, Downs RW, Levine MA, Marx SJ, Stock JL, Saxe AW, Brennan MF, Aurbach GD. Intraoperative measurements of urinary cyclic AMP to guide surgery for primary hyperparathyroidism. The New England Journal of Medicine. 303: 1457-60. PMID 6253789 DOI: 10.1056/NEJM198012183032505  0.68
1980 Levine MA, Downs RW, Singer M, Marx SJ, Aurbach GD, Spiegel AM. Deficient activity of guanine nucleotide regulatory protein in erythrocytes from patients with pseudohypoparathyroidism. Biochemical and Biophysical Research Communications. 94: 1319-24. PMID 6249307 DOI: 10.1016/0006-291X(80)90563-X  0.68
1980 Downs RW, Spiegel AM, Singer M, Reen S, Aurbach GD. Fluoride stimulation of adenylate cyclase is dependent on the guanine nucleotide regulatory protein. The Journal of Biological Chemistry. 255: 949-54. PMID 6243302  0.68
1979 Spiegel AM, Downs RW, Aurbach GD. Separation of a guanine nucleotide regulatory unit from the adenylate cyclase complex with GTP affinity chromatography. Journal of Cyclic Nucleotide Research. 5: 3-17. PMID 438399  0.68
1979 Brown EM, Broadus AE, Brennan MF, Gardner DG, Marx SJ, Spiegel AM, Downs RW, Attie M, Aurbach GD. Direct comparison in vivo and in vitro of suppressibility of parathyroid function by calcium in primary hyperparathyroidism. The Journal of Clinical Endocrinology and Metabolism. 48: 604-10. PMID 429506 DOI: 10.1210/jcem-48-4-604  0.68
1979 Brennan MF, Brown EM, Spiegel AM, Marx SJ, Doppman JL, Jones DC, Aurbach GD. Autotransplantation of cryopreserved parathyroid tissue in man. Annals of Surgery. 189: 139-42. PMID 426546  0.68
1979 Brown EM, Brennan MF, Broadus AE, Marx SJ, Gardner DG, Spiegel AM, Downs RW, Attie MF, Aurbach GD. Human parathyroid autografts: comparison of function in vivo and in vitro. The Journal of Clinical Endocrinology and Metabolism. 48: 648-54. PMID 219003 DOI: 10.1210/jcem-48-4-648  0.68
1978 Brown EM, Brennan MF, Hurwitz S, Windeck R, Marx SJ, Spiegel AM, Koehler JO, Gardner DG, Aurbach GD. Dispersed cells prepared from human parathyroid glands: distinct calcium sensitivity of adenomas vs. primary hyperplasia. The Journal of Clinical Endocrinology and Metabolism. 46: 267-75. PMID 750604 DOI: 10.1210/jcem-46-2-267  0.68
1978 Brennan MF, Brown EM, Marx SJ, Spiegel AM, Broadus AE, Doppman JL, Webber B, Aurbach GD. Recurrent hyperparathyroidism from an autotransplanted parathyroid adenoma. The New England Journal of Medicine. 299: 1057-9. PMID 703772 DOI: 10.1056/NEJM197811092991909  0.68
1978 Marx SJ, Spiegel AM, Brown EM, Koehler JO, Gardner DG, Brennan MF, Aurbach GD. Divalent cation metabolism. Familial hypocalciuric hypercalcemia versus typical primary hyperparathyroidism. The American Journal of Medicine. 65: 235-42. PMID 686009 DOI: 10.1016/0002-9343(78)90814-8  0.68
1978 Brennan MF, Doppman JL, Marx SJ, Spiegel AM, Brown EM, Aurbach GD. Reoperative parathyroid surgery for persistent hyperparathyroidism. Surgery. 83: 669-76. PMID 644460  0.68
1978 Marx SJ, Spiegel AM, Brown EM, Windeck R, Gardner DG, Downs RW, Attie M, Aurbach GD. Circulating parathyroid hormone activity: familial hypocalciuric hypercalcemia versus typical primary hyperparathyroidism. The Journal of Clinical Endocrinology and Metabolism. 47: 1190-7. PMID 233692 DOI: 10.1210/jcem-47-6-1190  0.68
1978 Spiegel AM, Marx SJ, Brennan MF, Brown EM, Koehler JO, Aurbach GD. Urinary cAMP excretion during surgery: an index of successful parathyroidectomy in patients with primary hyperparathyroidism. The Journal of Clinical Endocrinology and Metabolism. 47: 537-42. PMID 233674 DOI: 10.1210/jcem-47-3-537  0.68
1978 Spiegel AM, Doppman JL, Marx SJ, Brennan MF, Brown EM, Downs RW, Gardner DG, Attie M, Aurbach GD. Preoperative localization of abnormal parathyroid: neck massage versus arteriography and selective venous sampling. Annals of Internal Medicine. 89: 935-6. PMID 214001  0.68
1977 Spiegel AM, Downs RW, Aurbach GD. Guanosine 5', alpha-beta-methylene, triphosphate, a novel GTP analog, causes persistent activation of adenylate cyclase: evidence against pyrophosphorylation mechanism. Biochemical and Biophysical Research Communications. 76: 758-64. PMID 197925 DOI: 10.1016/0006-291X(77)91565-0  0.68
1977 Bilezikian JP, Spiegel AM, Gammon DE, Aurbach GD. The role of guanyl nucleotides in the expression on of catecholamine-responsive adenylate cyclase during maturation of the rat reticulocyte. Molecular Pharmacology. 13: 786-95. PMID 197394  0.68
1977 Bilezikian JP, Spiegel AM, Brown EM, Aurbach GD. Identification and persistence of beta adrenergic receptors during maturation of the rat reticulocyte. Molecular Pharmacology. 13: 775-85. PMID 197393  0.68
Show low-probability matches.