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Elizabeth E. Rhoades, Ph.D. - Publications

Affiliations: 
Molecular Biophysics and Biochemistry Yale University, New Haven, CT 
 Chemistry University of Pennsylvania, Philadelphia, PA, United States 
Area:
Biological, Chemical Physics and Physical Chemistry
Website:
http://medicine.yale.edu/mbb/faculty/elizabeth_rhoades.profile
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136 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ramirez J, Pancoe SX, Rhoades E, Petersson EJ. The Effects of Lipids on α-Synuclein Aggregation In Vitro. Biomolecules. 13. PMID 37892158 DOI: 10.3390/biom13101476  0.331
2023 Birol M, Muñoz IID, Rhoades E. The C-terminus of α-Synuclein Regulates its Dynamic Cellular Internalization by Neurexin 1β. Molecular Biology of the Cell. 34: br21. PMID 37729016 DOI: 10.1091/mbc.E22-11-0496  0.39
2023 Galesic A, Pan B, Ramirez J, Rhoades E, Pratt MR, Petersson EJ. Combining non-canonical amino acid mutagenesis and native chemical ligation for multiply modifying proteins: A case study of α-synuclein post-translational modifications. Methods (San Diego, Calif.). 218: 101-109. PMID 37549799 DOI: 10.1016/j.ymeth.2023.08.002  0.364
2023 Pan B, Gardner SM, Schultz K, Perez RM, Deng S, Shimogawa M, Sato K, Rhoades E, Marmorstein R, Petersson EJ. Semi-Synthetic CoA-α-Synuclein Constructs Trap N-Terminal Acetyltransferase NatB for Binding Mechanism Studies. Journal of the American Chemical Society. 145: 14019-14030. PMID 37319422 DOI: 10.1021/jacs.3c03887  0.391
2023 Pan B, Gardner S, Schultz K, Perez RM, Deng S, Shimogawa M, Sato K, Rhoades E, Marmorstein R, Petersson EJ. Semi-synthetic CoA-α-Synuclein Constructs Trap N-terminal Acetyltransferase NatB for Binding Mechanism Studies. Biorxiv : the Preprint Server For Biology. PMID 37066334 DOI: 10.1101/2023.04.03.535351  0.391
2022 Pan B, Shimogawa M, Zhao J, Rhoades E, Kashina A, Petersson EJ. Cysteine-Based Mimic of Arginylation Reproduces Neuroprotective Effects of the Authentic Post-Translational Modification on α-Synuclein. Journal of the American Chemical Society. PMID 35451816 DOI: 10.1021/jacs.2c02499  0.361
2020 Pan B, Kamo N, Shimogawa M, Huang Y, Kashina A, Rhoades E, Petersson EJ. Effects of Glutamate Arginylation on α-Synuclein: Studying an Unusual Post-Translational Modification through Semisynthesis. Journal of the American Chemical Society. PMID 33337869 DOI: 10.1021/jacs.0c10054  0.331
2020 Knox SL, Steinauer A, Alpha-Cobb G, Trexler A, Rhoades E, Schepartz A. Quantification of protein delivery in live cells using fluorescence correlation spectroscopy. Methods in Enzymology. 641: 477-505. PMID 32713536 DOI: 10.1016/Bs.Mie.2020.05.007  0.751
2020 Wickramasinghe SP, Rhoades E. Measuring Interactions Between Tau and Aggregation Inducers with Single-Molecule Förster Resonance Energy Transfer. Methods of Molecular Biology. 2141: 755-775. PMID 32696388 DOI: 10.1007/978-1-0716-0524-0_39  0.421
2020 Metskas LA, Rhoades E. Single-Molecule FRET of Intrinsically Disordered Proteins. Annual Review of Physical Chemistry. 71: 391-414. PMID 32097582 DOI: 10.1146/Annurev-Physchem-012420-104917  0.357
2020 Pan B, Rhoades E, Petersson EJ. Chemoenzymatic Semisynthesis of Phosphorylated α-Synuclein Enables Identification of a Bidirectional Effect on Fibril Formation. Acs Chemical Biology. PMID 32065743 DOI: 10.1021/Acschembio.9B01038  0.355
2020 Fung HYJ, McKibben KM, Ramirez J, Gupta K, Rhoades E. Structural Characterization of Tau in Fuzzy Tau:Tubulin Complexes. Structure (London, England : 1993). PMID 31995742 DOI: 10.1016/J.Str.2020.01.004  0.387
2019 McKibben KM, Rhoades E. Independent tubulin binding and polymerization by the proline-rich region of Tau is regulated by Tau's N-terminal domain Journal of Biological Chemistry. 294: 19381-19394. PMID 31699899 DOI: 10.1074/Jbc.Ra119.010172  0.425
2019 Lo CH, Lim CK, Ding Z, Wickramasinghe SP, Braun AR, Ashe KH, Rhoades E, Thomas DD, Sachs JN. Targeting the ensemble of heterogeneous tau oligomers in cells: A novel small molecule screening platform for tauopathies. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31653529 DOI: 10.1016/J.Jalz.2019.06.4954  0.342
2019 Wickramasinghe SP, Lempart J, Merens HE, Murphy J, Huettemann P, Jakob U, Rhoades E. Polyphosphate Initiates Tau Aggregation through Intra- and Intermolecular Scaffolding. Biophysical Journal. PMID 31400913 DOI: 10.1016/J.Bpj.2019.07.028  0.426
2019 Rhoades E. Proteins: Disorder, Folding, and Crowding. Biophysical Journal. 117: 3-4. PMID 31230706 DOI: 10.1016/J.Bpj.2019.06.014  0.318
2019 Birol M, Wojcik SP, Miranker AD, Rhoades E. Identification of N-linked glycans as specific mediators of neuronal uptake of acetylated α-Synuclein. Plos Biology. 17: e3000318. PMID 31211781 DOI: 10.1371/Journal.Pbio.3000318  0.368
2019 Daniels MJ, Nourse JB, Kim H, Sainati V, Schiavina M, Murrali MG, Pan B, Ferrie JJ, Haney CM, Moons R, Gould NS, Natalello A, Grandori R, Sobott F, Petersson EJ, ... Rhoades E, et al. Cyclized NDGA modifies dynamic α-synuclein monomers preventing aggregation and toxicity. Scientific Reports. 9: 2937. PMID 30814575 DOI: 10.1038/S41598-019-39480-Z  0.42
2019 McKibben K, Rhoades E. Tau's Proline Rich Region Dominates Tubulin Binding Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.872  0.379
2019 Birol M, Wojcik SP, Miranker AD, Rhoades E. α-Synuclein Binds Extracellular Complex N-Linked Glycans Biophysical Journal. 116: 495a. DOI: 10.1016/J.Bpj.2018.11.2670  0.374
2019 Musila JM, Rhoades E. Structural Evaluation of Aromatic Residues in α-Syn and their Role in Glycan Binding and Cellular Uptake Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.2664  0.393
2019 Fung HYJ, Rhoades E. Probing Structural Features of Tau Binding to Tubulin and Microtubules Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.1392  0.361
2018 Wójcik S, Birol M, Rhoades E, Miranker AD, Levine ZA. Targeting the Intrinsically Disordered Proteome Using Small-Molecule Ligands. Methods in Enzymology. 611: 703-734. PMID 30471705 DOI: 10.1016/Bs.Mie.2018.09.036  0.362
2018 Espinoza-Sanchez S, Metskas LA, Chou SZ, Rhoades E, Pollard TD. Conformational changes in Arp2/3 complex induced by ATP, WASp-VCA, and actin filaments. Proceedings of the National Academy of Sciences of the United States of America. PMID 30150414 DOI: 10.1073/Pnas.1717594115  0.364
2018 Braun AR, Lacy MM, Ducas VC, Chen Z, Baumgart T, Rhoades E, Sachs JN. Correction to: α-Synuclein's Uniquely Long Amphipathic Helix Enhances its Membrane Binding and Remodeling Capacity. The Journal of Membrane Biology. PMID 30054671 DOI: 10.1007/S00232-018-0042-Y  0.777
2018 Birol M, Kumar S, Rhoades E, Miranker AD. Conformational switching within dynamic oligomers underpins toxic gain-of-function by diabetes-associated amyloid. Nature Communications. 9: 1312. PMID 29615609 DOI: 10.1038/S41467-018-03651-9  0.357
2018 Ferrie JJ, Haney CM, Yoon J, Pan B, Lin YC, Fakhraai Z, Rhoades E, Nath A, Petersson EJ. Using a FRET Library with Multiple Probe Pairs To Drive Monte Carlo Simulations of α-Synuclein. Biophysical Journal. 114: 53-64. PMID 29320696 DOI: 10.1016/J.Bpj.2017.11.006  0.395
2018 Fung HYJ, Birol M, Rhoades E. IDPs in macromolecular complexes: the roles of multivalent interactions in diverse assemblies. Current Opinion in Structural Biology. 49: 36-43. PMID 29306779 DOI: 10.1016/J.Sbi.2017.12.007  0.381
2018 Acosta K, Rhoades E. Characterizing Alpha-Synuclein Binding to Glycans Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.467  0.342
2018 Ferrie JJ, Haney CM, Yoon J, Pan B, Rhoades E, Nath A, Petersson EJ. Utilzing Forster Resonance Energy Transfer (FRET) and Photocrosslinking to Visualize Conformational Changes of Alpha-Synuclein Biophysical Journal. 114: 586a-587a. DOI: 10.1016/J.Bpj.2017.11.3210  0.3
2018 McKibben K, Rhoades E. N-terminal Inserts Impact the Global Conformation of Tau and the Tau-Tubulin Complex Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.2777  0.331
2018 Merens HE, Wickramasinghe S, Lempart J, Jakob U, Rhoades E. Polyphosphate-Induced Aggregation-Prone Conformations of Tau Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.2377  0.356
2018 Wickramasinghe S, Merens H, Lempart J, Jakob U, Rhoades E. Characterization of the Aggregation-Prone Ensemble of Tau in the Presence of Polyphosphates Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.2041  0.336
2017 Quach K, LaRochelle J, Li XH, Rhoades E, Schepartz A. Unique arginine array improves cytosolic localization of hydrocarbon-stapled peptides. Bioorganic & Medicinal Chemistry. PMID 29150077 DOI: 10.1016/J.Bmc.2017.11.008  0.339
2017 Melo AM, Elbaum-Garfinkle S, Rhoades E. Insights into tau function and dysfunction through single-molecule fluorescence Methods in Cell Biology. 141: 27-44. PMID 28882307 DOI: 10.1016/Bs.Mcb.2017.06.010  0.437
2017 Li XH, Rhoades E. Heterogeneous Tau-Tubulin Complexes Accelerate Microtubule Polymerization. Biophysical Journal. 112: 2567-2574. PMID 28636913 DOI: 10.1016/J.Bpj.2017.05.006  0.376
2017 Braun AR, Lacy MM, Ducas VC, Rhoades E, Sachs JN. α-Synuclein's Uniquely Long Amphipathic Helix Enhances its Membrane Binding and Remodeling Capacity. The Journal of Membrane Biology. PMID 28239748 DOI: 10.1007/S00232-017-9946-1  0.831
2017 Toal S, Rhoades E. α-Synuclein: A Functional Role as a Regulator of SNARE-Mediated Fusion Biophysical Journal. 112: 78a. DOI: 10.1016/J.Bpj.2016.11.466  0.455
2017 Birol M, Kumar S, Rhoades E, Miranker A. Toxic and Non-Toxic Forms of Membrane Poration are Mediated by Structurally Distinct States of Islet Amyloid Polypeptide Biophysical Journal. 112: 503a. DOI: 10.1016/J.Bpj.2016.11.2724  0.379
2017 Toal S, Trexler A, DeWitt D, Brown M, Rhoades E. Determining the Role of N-Terminal Acetylation on α-Synuclein Function Biophysical Journal. 112: 366a. DOI: 10.1016/J.Bpj.2016.11.1982  0.766
2017 Melo AM, Rhoades E. Exploring the Functional and Structural Impact of Disease-Associated Mutants of Tau Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.1715  0.438
2016 Melo AM, Coraor J, Alpha-Cobb G, Elbaum-Garfinkle S, Nath A, Rhoades E. A functional role for intrinsic disorder in the tau-tubulin complex. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911791 DOI: 10.1073/Pnas.1610137113  0.453
2016 Metskas LA, Rhoades E. Order-Disorder Transitions in the Cardiac Troponin Complex. Journal of Molecular Biology. 428: 2965-2977. PMID 27395017 DOI: 10.1016/J.Jmb.2016.06.022  0.318
2016 Kumar S, Birol M, Schlamadinger DE, Wojcik SP, Rhoades E, Miranker AD. Foldamer-mediated manipulation of a pre-amyloid toxin. Nature Communications. 7: 11412. PMID 27108700 DOI: 10.1038/Ncomms11412  0.428
2016 West A, Brummel BE, Braun AR, Rhoades E, Sachs JN. Membrane remodeling and mechanics: Experiments and simulations of α-Synuclein. Biochimica Et Biophysica Acta. PMID 26972046 DOI: 10.1016/J.Bbamem.2016.03.012  0.492
2016 Toal S, DeWitt D, Trexler A, Brown M, Rhoades E. Assessing N-Terminal Modifications on Alpha-Synuclein Structure and Function Biophysical Journal. 110: 552a. DOI: 10.1016/J.Bpj.2015.11.2954  0.783
2016 Melo AM, Cobb G, Coraor J, Elbaum-Garfinkle S, Rhoades E. Determining a Topological Model for TAU Bound to Tubulin Heterodimers Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.265  0.457
2015 Tavoulari S, Margheritis E, Nagarajan A, DeWitt DC, Zhang YW, Rosado E, Ravera S, Rhoades E, Forrest LR, Rudnick G. Two Na+ Sites Control Conformational Change in a Neurotransmitter Transporter Homolog. The Journal of Biological Chemistry. PMID 26582198 DOI: 10.1074/Jbc.M115.692012  0.311
2015 Li XH, Culver JA, Rhoades E. Tau Binds to Multiple Tubulin Dimers with Helical Structure. Journal of the American Chemical Society. 137: 9218-21. PMID 26165802 DOI: 10.1021/Jacs.5B04561  0.441
2015 Jülich D, Cobb G, Melo AM, McMillen P, Lawton AK, Mochrie SG, Rhoades E, Holley SA. Cross-Scale Integrin Regulation Organizes ECM and Tissue Topology. Developmental Cell. PMID 26096733 DOI: 10.1016/J.Devcel.2015.05.005  0.34
2015 Nath A, Schlamadinger DE, Rhoades E, Miranker AD. Structure-Based Small Molecule Modulation of a Pre-Amyloid State: Pharmacological Enhancement of IAPP Membrane-Binding and Toxicity. Biochemistry. 54: 3555-64. PMID 25966003 DOI: 10.1021/Acs.Biochem.5B00052  0.432
2015 Metskas LA, Rhoades E. Folding upon phosphorylation: translational regulation by a disorder-to-order transition. Trends in Biochemical Sciences. 40: 243-4. PMID 25769422 DOI: 10.1016/J.Tibs.2015.02.007  0.355
2015 Kumar S, Schlamadinger DE, Brown MA, Dunn JM, Mercado B, Hebda JA, Saraogi I, Rhoades E, Hamilton AD, Miranker AD. Islet amyloid-induced cell death and bilayer integrity loss share a molecular origin targetable with oligopyridylamide-based α-helical mimetics. Chemistry & Biology. 22: 369-78. PMID 25754474 DOI: 10.1016/J.Chembiol.2015.01.006  0.415
2015 Esposito DL, Nguyen JB, DeWitt DC, Rhoades E, Modis Y. Physicochemical requirements and kinetics of membrane fusion of flavivirus-like particles. The Journal of General Virology. PMID 25740960 DOI: 10.1099/Vir.0.000113  0.382
2015 Shi Z, Sachs JN, Rhoades E, Baumgart T. Biophysics of α-synuclein induced membrane remodelling. Physical Chemistry Chemical Physics : Pccp. 17: 15561-8. PMID 25665896 DOI: 10.1039/C4Cp05883F  0.694
2015 Ciubotaru M, Surleac MD, Metskas LA, Koo P, Rhoades E, Petrescu AJ, Schatz DG. The architecture of the 12RSS in V(D)J recombination signal and synaptic complexes. Nucleic Acids Research. 43: 917-31. PMID 25550426 DOI: 10.1093/Nar/Gku1348  0.327
2015 Metskas LA, Rhoades E. Conformation and Dynamics of the Troponin i C-Terminal Domain: Combining Single-Molecule and Computational Approaches for a Disordered Protein Region Journal of the American Chemical Society. 137: 11962-11969. DOI: 10.1021/Jacs.5B04471  0.352
2015 Li X, Culver J, Rhoades E. Towards a Model of the Tau-Tubulin Complex Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.2785  0.382
2015 Brown MA, Rhoades E, Miranker AD. A Role for Unstructured Residues in the Induction of Membrane Poration by Pre-Amyloid Assemblies of Islet Amyloid Polypeptide Biophysical Journal. 108: 496a. DOI: 10.1016/J.Bpj.2014.11.2712  0.448
2015 Coraor J, Melo AM, Cobb G, Rhoades E. A Comparison of the Conformational Changes of Tau Isoforms in the Tau-Tubulin Complex Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.2460  0.436
2015 Melo AM, Cobb G, Coraor J, Elbaum-Garfinkle S, Rhoades E. Single-Molecule FRET Reveals an Extended Structure of Tau Bound to Tubulin Heterodimers Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.2444  0.447
2015 Metskas LA, Rhoades E. Conformation of the Troponin I C-Terminal Domain in Silico and in vitro: A Consideration of Dynamics in Comparing Simulation and Experiment Biophysical Journal. 108: 344a. DOI: 10.1016/J.Bpj.2014.11.1885  0.368
2014 Braun AR, Lacy MM, Ducas VC, Rhoades E, Sachs JN. α-Synuclein-induced membrane remodeling is driven by binding affinity, partition depth, and interleaflet order asymmetry. Journal of the American Chemical Society. 136: 9962-72. PMID 24960410 DOI: 10.1021/Ja5016958  0.833
2014 Elbaum-Garfinkle S, Cobb G, Compton JT, Li XH, Rhoades E. Tau mutants bind tubulin heterodimers with enhanced affinity. Proceedings of the National Academy of Sciences of the United States of America. 111: 6311-6. PMID 24733915 DOI: 10.1073/Pnas.1315983111  0.427
2014 Ducas VC, Rhoades E. Investigation of intramolecular dynamics and conformations of α-, β- and γ-synuclein. Plos One. 9: e86983. PMID 24489820 DOI: 10.1371/Journal.Pone.0086983  0.806
2014 Munro JB, Nath A, Färber M, Datta SA, Rein A, Rhoades E, Mothes W. A conformational transition observed in single HIV-1 Gag molecules during in vitro assembly of virus-like particles. Journal of Virology. 88: 3577-85. PMID 24403576 DOI: 10.1128/Jvi.03353-13  0.349
2014 Fribourgh JL, Nguyen HC, Wolfe LS, Dewitt DC, Zhang W, Yu XF, Rhoades E, Xiong Y. Core binding factor beta plays a critical role by facilitating the assembly of the Vif-cullin 5 E3 ubiquitin ligase. Journal of Virology. 88: 3309-19. PMID 24390320 DOI: 10.1128/Jvi.03824-13  0.342
2014 Smith WW, Ho P, Rhoades E, O'Hern C. Molecular Simulations of the Dynamics of Disordered Proteins Biophysical Journal. 106: 426a. DOI: 10.1016/J.Bpj.2013.11.2402  0.434
2014 Rhoades E, Elbaum-Garfinkle S, Cobb G, Compton JT, Li X. Increased Affinity for Tubulin Impairs Tau Function Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.1585  0.439
2014 Li X, Rhoades E. Mapping the Structure of Tau Using Single Molecule FRET Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.1583  0.384
2014 Lacy MM, Ducas VC, Braun AR, Sachs JN, Rhoades E. Assessing the Structural Dynamics and Membrane Interactions of the Disordered Protein Alpha-Synuclein Biophysical Journal. 106: 267a-268a. DOI: 10.1016/J.Bpj.2013.11.1568  0.833
2014 Rudnick G, Tavoulari S, Zhang Y, DeWitt D, Nagarajan A, Rosado E, Ravera S, Kreuder A, Forrest LR, Rhoades E. The Role of Sodium Sites in LeuT Conformational Changes Biophysical Journal. 106: 228a-229a. DOI: 10.1016/J.Bpj.2013.11.1337  0.337
2013 DeWitt DC, Rhoades E. α-Synuclein can inhibit SNARE-mediated vesicle fusion through direct interactions with lipid bilayers. Biochemistry. 52: 2385-7. PMID 23528131 DOI: 10.1021/Bi4002369  0.446
2013 Capraro BR, Shi Z, Wu T, Chen Z, Dunn JM, Rhoades E, Baumgart T. Kinetics of endophilin N-BAR domain dimerization and membrane interactions. The Journal of Biological Chemistry. 288: 12533-43. PMID 23482561 DOI: 10.1074/Jbc.M112.435511  0.679
2013 Nath A, Rhoades E. A flash in the pan: dissecting dynamic amyloid intermediates using fluorescence. Febs Letters. 587: 1096-105. PMID 23458258 DOI: 10.1016/J.Febslet.2013.02.044  0.416
2013 Ciubotaru M, Trexler AJ, Spiridon LN, Surleac MD, Rhoades E, Petrescu AJ, Schatz DG. RAG and HMGB1 create a large bend in the 23RSS in the V(D)J recombination synaptic complexes. Nucleic Acids Research. 41: 2437-54. PMID 23293004 DOI: 10.1093/Nar/Gks1294  0.731
2013 Trexler AJ, Rhoades E. Function and dysfunction of α-synuclein: probing conformational changes and aggregation by single molecule fluorescence. Molecular Neurobiology. 47: 622-31. PMID 22983916 DOI: 10.1007/S12035-012-8338-X  0.776
2013 Elbaum-Garfinkle S, Cobb G, Nath A, Rhoades E. 152 Order from disorder: defining structure in disordered proteins Journal of Biomolecular Structure & Dynamics. 31: 98-98. DOI: 10.1080/07391102.2013.786394  0.382
2013 Nath A, Schlamadinger DE, Dodhia S, Rhoades E, Miranker AD. Screening and Design of New Modulators of IAPP Membrane-Binding and Toxicity Biophysical Journal. 104: 56a-57a. DOI: 10.1016/J.Bpj.2012.11.351  0.471
2013 Dunn JM, Miranker AD, Rhoades E. Membrane Geometry Alters the Interaction between Islet Amyloid Polypeptide and Lipid Bilayers Biophysical Journal. 104: 592a. DOI: 10.1016/J.Bpj.2012.11.3287  0.448
2013 Ducas VC, Rhoades E. Understanding the Role of Intrachain Diffusion in Protein Self-Association Biophysical Journal. 104: 52a. DOI: 10.1016/J.Bpj.2012.11.328  0.814
2013 Smith WW, Schreck CF, Nath A, Rhoades E, O'Hern CS. Molecular Simulations of the Fluctuating Conformational Dynamics of α-Synuclein Biophysical Journal. 104: 52a. DOI: 10.1016/J.Bpj.2012.11.327  0.41
2013 DeWitt DC, Rhoades E. Alpha Synuclein Inhibits Snare Mediated Vesicle Fusion Biophysical Journal. 104: 51. DOI: 10.1016/J.Bpj.2012.11.326  0.453
2013 Metskas LA, Rhoades E. Conformation and Dynamics of the Troponin I C-Terminal Domain Biophysical Journal. 104: 482. DOI: 10.1016/J.Bpj.2012.11.2662  0.373
2012 Smith WW, Schreck CF, Hashem N, Soltani S, Nath A, Rhoades E, O'Hern CS. Molecular simulations of the fluctuating conformational dynamics of intrinsically disordered proteins. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 86: 041910. PMID 23214618 DOI: 10.1103/Physreve.86.041910  0.403
2012 Nath A, Sammalkorpi M, DeWitt DC, Trexler AJ, Elbaum-Garfinkle S, O'Hern CS, Rhoades E. The conformational ensembles of α-synuclein and tau: combining single-molecule FRET and simulations. Biophysical Journal. 103: 1940-9. PMID 23199922 DOI: 10.1016/J.Bpj.2012.09.032  0.763
2012 Elbaum-Garfinkle S, Rhoades E. Identification of an aggregation-prone structure of tau. Journal of the American Chemical Society. 134: 16607-13. PMID 22998648 DOI: 10.1021/Ja305206M  0.476
2012 Ducas VC, Rhoades E. Quantifying interactions of β-synuclein and γ-synuclein with model membranes. Journal of Molecular Biology. 423: 528-39. PMID 22922472 DOI: 10.1016/J.Jmb.2012.08.008  0.827
2012 Trexler AJ, Rhoades E. N-Terminal acetylation is critical for forming α-helical oligomer of α-synuclein. Protein Science : a Publication of the Protein Society. 21: 601-5. PMID 22407793 DOI: 10.1002/Pro.2056  0.769
2012 Braun AR, Sevcsik E, Chin P, Rhoades E, Tristram-Nagle S, Sachs JN. α-Synuclein induces both positive mean curvature and negative Gaussian curvature in membranes. Journal of the American Chemical Society. 134: 2613-20. PMID 22211521 DOI: 10.1021/Ja208316H  0.48
2012 Braun AR, Sevcsik E, Rhoades E, Tristram-Nagle S, Sachs JN. The Nature of Membrane Curvature-Induction by Amphipathic α-Helices Relies upon Protein Length: Simulations of α-Synuclein and H0 Biophysical Journal. 102: 237a. DOI: 10.1016/J.Bpj.2011.11.1301  0.459
2012 Rhoades E. Using FCS to Study Protein Disorder and Aggregation Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.130  0.562
2011 Nath A, Miranker AD, Rhoades E. A membrane-bound antiparallel dimer of rat islet amyloid polypeptide. Angewandte Chemie (International Ed. in English). 50: 10859-62. PMID 21948544 DOI: 10.1002/Anie.201102887  0.39
2011 Last NB, Rhoades E, Miranker AD. Islet amyloid polypeptide demonstrates a persistent capacity to disrupt membrane integrity. Proceedings of the National Academy of Sciences of the United States of America. 108: 9460-5. PMID 21606325 DOI: 10.1073/Pnas.1102356108  0.426
2011 Cao W, Coman MM, Ding S, Henn A, Middleton ER, Bradley MJ, Rhoades E, Hackney DD, Pyle AM, De La Cruz EM. Mechanism of Mss116 ATPase reveals functional diversity of DEAD-Box proteins. Journal of Molecular Biology. 409: 399-414. PMID 21501623 DOI: 10.1016/J.Jmb.2011.04.004  0.707
2011 Sevcsik E, Trexler AJ, Dunn JM, Rhoades E. Allostery in a disordered protein: oxidative modifications to α-synuclein act distally to regulate membrane binding. Journal of the American Chemical Society. 133: 7152-8. PMID 21491910 DOI: 10.1021/Ja2009554  0.799
2011 Nath A, O'Hern C, Miranker AD, Rhoades E. Single molecule studies of unstructured protein function and dynamics Optics Infobase Conference Papers. DOI: 10.1364/Fio.2011.Ftuh1  0.425
2011 Sevcsik E, DeWitt DC, Trexler A, Rhoades E. Nitration of Tyrosine Residues in Alpha-Synuclein Reduces Vesicle Binding Through Electrostatic and Allosteric Effects Biophysical Journal. 100: 63a. DOI: 10.1016/J.Bpj.2010.12.542  0.793
2011 Trexler A, Rhoades E. Characterization and Single Molecule Conformational Studies of Soluble Alpha-Synuclein Oligomers Biophysical Journal. 100: 532a. DOI: 10.1016/J.Bpj.2010.12.3107  0.776
2011 Elbaum-Garfinkle S, Rhoades E. Investigating Tau Conformations Using Single Molecule Fluorescence Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.281  0.459
2011 Last NB, Rhoades E, Miranker AD. Evolution of Membrane Leakage by Pre-Amyloidogenic Oligomers of Islet Amyloid Polypeptide Biophysical Journal. 100: 350a. DOI: 10.1016/J.Bpj.2010.12.2110  0.37
2011 Middleton E, Rhoades E. αα-Synuclein Interactions with Hsp70 Biophysical Journal. 100: 228a. DOI: 10.1016/J.Bpj.2010.12.1460  0.769
2011 Nath A, Atkins WM, Miranker AD, Rhoades E. Single-Molecule Enzymology: Studies on Glutathione-S-Transferases Biophysical Journal. 100: 193a. DOI: 10.1016/J.Bpj.2010.12.1272  0.317
2010 Trexler AJ, Rhoades E. Single molecule characterization of α-synuclein in aggregation-prone states. Biophysical Journal. 99: 3048-55. PMID 21044603 DOI: 10.1016/J.Bpj.2010.08.056  0.776
2010 Middleton ER, Rhoades E. Effects of curvature and composition on α-synuclein binding to lipid vesicles. Biophysical Journal. 99: 2279-88. PMID 20923663 DOI: 10.1016/J.Bpj.2010.07.056  0.795
2010 Nath A, Trexler AJ, Koo P, Miranker AD, Atkins WM, Rhoades E. Single-molecule fluorescence spectroscopy using phospholipid bilayer nanodiscs. Methods in Enzymology. 472: 89-117. PMID 20580961 DOI: 10.1016/S0076-6879(10)72014-0  0.788
2010 Elbaum-Garfinkle S, Ramlall T, Rhoades E. The role of the lipid bilayer in tau aggregation. Biophysical Journal. 98: 2722-30. PMID 20513417 DOI: 10.1016/J.Bpj.2010.03.013  0.499
2010 Hsiao HH, Nath A, Lin CY, Folta-Stogniew EJ, Rhoades E, Braddock DT. Quantitative characterization of the interactions among c-myc transcriptional regulators FUSE, FBP, and FIR. Biochemistry. 49: 4620-34. PMID 20420426 DOI: 10.1021/Bi9021445  0.345
2010 Ilagan RP, Rhoades E, Gruber DF, Kao HT, Pieribone VA, Regan L. A new bright green-emitting fluorescent protein--engineered monomeric and dimeric forms. The Febs Journal. 277: 1967-78. PMID 20345907 DOI: 10.1111/J.1742-4658.2010.07618.X  0.394
2010 Nath A, Miranker AD, Rhoades E. Pre-Amyloid States of Islet Amyloid Polypeptide Examined by Single-Particle Fluorescence Biophysical Journal. 98: 650a-651a. DOI: 10.1016/J.Bpj.2009.12.3566  0.468
2010 Ilagan R, Kao H, Gruber D, Rhoades E, Regan L. Characterization of New and Improved Fluorescent Proteins and their Applications Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.3284  0.347
2010 Sachs JN, Perlmutter JD, Braun AR, Sevcsik E, Tristram-Nagle S, Rhoades E. Probing the Membrane Deformations Induced by Binding of Membrane Proteins: Alpha-Synuclein and CRAC Biophysical Journal. 98: 487a-488a. DOI: 10.1016/J.Bpj.2009.12.2655  0.455
2010 Traina JM, Elbaum S, Rhoades E. Characterization of Tau Interactions with Lipid Vesicles Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.1961  0.721
2010 Ducas VC, Rhoades E. Monitoring the Lipid- Binding Properties of Beta- and Gamma- Synuclein using Fluorescence Correlation Spectroscopy (FCS) Biophysical Journal. 98: 259a. DOI: 10.1016/J.Bpj.2009.12.1408  0.822
2010 Trexler A, Rhoades E. Nature of the Low pH Alpha Synuclein Conformational State Revealed with Single Molecule Fluorescence Biophysical Journal. 98: 259a. DOI: 10.1016/J.Bpj.2009.12.1407  0.761
2010 Sevcsik E, Rhoades E. A Single Molecule Fluorescence Study on the Consequences of Alpha-Synuclein Oxidation Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.1406  0.534
2010 Middleton E, Rhoades E. Effects of Vesicle Diameter and Lipid Composition on α-Synuclein Binding Biophysical Journal. 98: 258a. DOI: 10.1016/J.Bpj.2009.12.1404  0.787
2009 Trexler AJ, Rhoades E. Alpha-synuclein binds large unilamellar vesicles as an extended helix. Biochemistry. 48: 2304-6. PMID 19220042 DOI: 10.1021/Bi900114Z  0.793
2009 Last NB, Rhoades E, Miranker AD. Single Particle Analysis of Liposome Leakage Induced by Islet Amyloid Polypeptide Biophysical Journal. 96: 158a. DOI: 10.1016/J.Bpj.2008.12.718  0.376
2009 Elbaum S, Traina J, Eliezer D, Rhoades E. Probing Tau-Vesicle Interactions Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.390  0.71
2009 Crevecoeur V, Rhoades E. Probing the Dynamics and Conformations of Free and Ligand-bound Gamma-synuclein Biophysical Journal. 96: 584a. DOI: 10.1016/J.Bpj.2008.12.3057  0.434
2009 Sevcsik E, Rhoades E. Effects of Oxidative Stress on Aggregation and Membrane Interaction of alpha-Synuclein Characterized by Single Molecule Fluorescence Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.2907  0.509
2009 Trexler A, Rhoades E. Single Molecule FRET On Alpha Synuclein Membrane-bound Conformational States Biophysical Journal. 96: 388a. DOI: 10.1016/J.Bpj.2008.12.2901  0.796
2009 Middleton E, Rhoades E. Effect of Vesicle Diameter on α-Synuclein Binding Biophysical Journal. 96: 319a. DOI: 10.1016/J.Bpj.2008.12.1598  0.805
2008 Nath A, Koo PK, Rhoades E, Atkins WM. Allosteric effects on substrate dissociation from cytochrome P450 3A4 in nanodiscs observed by ensemble and single-molecule fluorescence spectroscopy. Journal of the American Chemical Society. 130: 15746-7. PMID 18980315 DOI: 10.1021/Ja805772R  0.334
2008 Chen H, Rhoades E. Fluorescence characterization of denatured proteins. Current Opinion in Structural Biology. 18: 516-24. PMID 18675353 DOI: 10.1016/J.Sbi.2008.06.008  0.407
2008 Sherman E, Itkin A, Kuttner YY, Rhoades E, Amir D, Haas E, Haran G. Using fluorescence correlation spectroscopy to study conformational changes in denatured proteins. Biophysical Journal. 94: 4819-27. PMID 18326651 DOI: 10.1529/Biophysj.107.120220  0.769
2008 Park HY, Kim SA, Korlach J, Rhoades E, Kwok LW, Zipfel WR, Waxham MN, Webb WW, Pollack L. Conformational changes of calmodulin upon Ca2+ binding studied with a microfluidic mixer. Proceedings of the National Academy of Sciences of the United States of America. 105: 542-7. PMID 18178620 DOI: 10.1073/Pnas.0710810105  0.769
2007 Chen H, Rhoades E, Butler JS, Loh SN, Webb WW. Dynamics of equilibrium structural fluctuations of apomyoglobin measured by fluorescence correlation spectroscopy. Proceedings of the National Academy of Sciences of the United States of America. 104: 10459-64. PMID 17556539 DOI: 10.1073/Pnas.0704073104  0.534
2006 Park HY, Qiu X, Rhoades E, Korlach J, Kwok LW, Zipfel WR, Webb WW, Pollack L. Achieving uniform mixing in a microfluidic device: hydrodynamic focusing prior to mixing. Analytical Chemistry. 78: 4465-73. PMID 16808455 DOI: 10.1021/Ac060572N  0.748
2006 Rhoades E, Ramlall TF, Webb WW, Eliezer D. Quantification of alpha-synuclein binding to lipid vesicles using fluorescence correlation spectroscopy. Biophysical Journal. 90: 4692-700. PMID 16581836 DOI: 10.1529/Biophysj.105.079251  0.61
2005 Yuan C, Rhoades E, Heuer DM, Archer LA. Mismatch-induced DNA unbending upon duplex opening. Biophysical Journal. 89: 2564-73. PMID 16085769 DOI: 10.1529/Biophysj.105.065722  0.341
2004 Rhoades E, Cohen M, Schuler B, Haran G. Two-state folding observed in individual protein molecules. Journal of the American Chemical Society. 126: 14686-7. PMID 15535670 DOI: 10.1021/Ja046209K  0.635
2003 Rhoades E, Gafni A. Micelle formation by a fragment of human islet amyloid polypeptide. Biophysical Journal. 84: 3480-7. PMID 12719273 DOI: 10.1016/S0006-3495(03)70068-X  0.564
2003 Rhoades E, Gussakovsky E, Haran G. Watching proteins fold one molecule at a time. Proceedings of the National Academy of Sciences of the United States of America. 100: 3197-202. PMID 12612345 DOI: 10.1073/Pnas.2628068100  0.636
2000 Rhoades E, Agarwal J, Gafni A. Aggregation of an amyloidogenic fragment of human islet amyloid polypeptide. Biochimica Et Biophysica Acta. 1476: 230-8. PMID 10669788 DOI: 10.1016/S0167-4838(99)00248-4  0.532
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