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Spencer John Williams, Ph.D. - Publications

Affiliations: 
2002- Chemistry University of Melbourne, Parkville, Victoria, Australia 
Area:
Carbohydrates
Website:
http://www2.chemistry.unimelb.edu.au/staff/sjwill/research/

150 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Nagata M, Toyonaga K, Ishikawa E, Haji S, Okahashi N, Takahashi M, Izumi Y, Imamura A, Takato K, Ishida H, Nagai S, Illarionov P, Stocker BL, Timmer MSM, Smith DGM, ... Williams SJ, et al. Helicobacter pylori metabolites exacerbate gastritis through C-type lectin receptors. The Journal of Experimental Medicine. 218. PMID 32991669 DOI: 10.1084/jem.20200815  0.56
2020 Nguyen T, Hosono Y, Shimizu T, Yamasaki S, Williams SJ. steryl 6--acyl-α-D-mannosides agonize signalling through Mincle. Chemical Communications (Cambridge, England). PMID 33196722 DOI: 10.1039/d0cc06263d  0.56
2020 Sobala ŁF, Fernandes PZ, Hakki Z, Thompson AJ, Howe JD, Hill M, Zitzmann N, Davies S, Stamataki Z, Butters TD, Alonzi DS, Williams SJ, Davies GJ. Structure of human endo-α-1,2-mannosidase (MANEA), an antiviral host-glycosylation target. Proceedings of the National Academy of Sciences of the United States of America. PMID 33154157 DOI: 10.1073/pnas.2013620117  0.56
2020 Smith DGM, Ito E, Yamasaki S, Williams SJ. Cholesteryl 6--acyl-α-glucosides from diverse spp. signal through the C-type lectin receptor Mincle. Organic & Biomolecular Chemistry. PMID 32996960 DOI: 10.1039/d0ob01776k  0.56
2020 Williams SJ, Goddard-Borger ED. α-glucosidase inhibitors as host-directed antiviral agents with potential for the treatment of COVID-19. Biochemical Society Transactions. PMID 32510142 DOI: 10.1042/BST20200505  0.44
2020 Sobala LF, Speciale G, Zhu S, Raich L, Sannikova N, Thompson AJ, Hakki Z, Lu D, Shamsi Kazem Abadi S, Lewis AR, Rojas-Cervellera V, Bernardo-Seisdedos G, Zhang Y, Millet O, Jiménez-Barbero J, ... ... Williams SJ, et al. An Epoxide Intermediate in Glycosidase Catalysis. Acs Central Science. 6: 760-770. PMID 32490192 DOI: 10.1021/acscentsci.0c00111  0.56
2020 Li J, Epa R, Scott NE, Skoneczny D, Sharma M, Snow AJD, Lingford JP, Goddard-Borger ED, Davies GJ, McConville MJ, Williams SJ. A sulfoglycolytic Entner-Doudoroff pathway in bv. SRDI565. Applied and Environmental Microbiology. PMID 32444469 DOI: 10.1128/AEM.00750-20  0.56
2020 Smith DGM, Hosono Y, Nagata M, Yamasaki S, Williams SJ. Design of potent Mincle signalling agonists based on an alkyl β-glucoside template. Chemical Communications (Cambridge, England). PMID 32182321 DOI: 10.1039/d0cc00670j  0.56
2020 Zhang Y, Mui JW, Arumaperuma T, Lingford JP, Goddard-Borger ED, White JM, Williams SJ. Concise synthesis of sulfoquinovose and sulfoquinovosyl diacylglycerides, and development of a fluorogenic substrate for sulfoquinovosidases. Organic & Biomolecular Chemistry. PMID 31894821 DOI: 10.1039/c9ob02540e  0.56
2019 Rovira C, Males A, Davies GJ, Williams SJ. Mannosidase mechanism: at the intersection of conformation and catalysis. Current Opinion in Structural Biology. 62: 79-92. PMID 31891872 DOI: 10.1016/j.sbi.2019.11.008  0.56
2019 Dumont L, Richardson MB, van der Peet P, Marapana DS, Triglia T, Dixon MWA, Cowman AF, Williams SJ, Tilley L, McConville MJ, Cobbold SA. The Metabolite Repair Enzyme Phosphoglycolate Phosphatase Regulates Central Carbon Metabolism and Fosmidomycin Sensitivity in Plasmodium falciparum. Mbio. 10. PMID 31822583 DOI: 10.1128/mBio.02060-19  0.88
2019 Almeida CF, Sundararaj S, Le Nours J, Praveena T, Cao B, Burugupalli S, Smith DGM, Patel O, Brigl M, Pellicci DG, Williams SJ, Uldrich AP, Godfrey DI, Rossjohn J. Distinct CD1d docking strategies exhibited by diverse Type II NKT cell receptors. Nature Communications. 10: 5242. PMID 31748533 DOI: 10.1038/s41467-019-12941-9  0.84
2019 Cartmell A, Muñoz-Muñoz J, Briggs JA, Ndeh DA, Lowe EC, Baslé A, Terrapon N, Stott K, Heunis T, Gray J, Yu L, Dupree P, Fernandes PZ, Shah S, Williams SJ, et al. Author Correction: A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation. Nature Microbiology. PMID 31541200 DOI: 10.1038/s41564-019-0584-5  0.56
2019 Sernee MF, Ralton JE, Nero TL, Sobala LF, Kloehn J, Vieira-Lara MA, Cobbold SA, Stanton L, Pires DEV, Hanssen E, Males A, Ward T, Bastidas LM, van der Peet PL, Parker MW, ... ... Williams SJ, et al. A Family of Dual-Activity Glycosyltransferase-Phosphorylases Mediates Mannogen Turnover and Virulence in Leishmania Parasites. Cell Host & Microbe. 26: 385-399.e9. PMID 31513773 DOI: 10.1016/j.chom.2019.08.009  0.56
2019 Males A, Speciale G, Williams SJ, Davies GJ. Distortion of mannoimidazole supports a B boat transition state for the family GH125 α-1,6-mannosidase from Clostridium perfringens. Organic & Biomolecular Chemistry. PMID 31407758 DOI: 10.1039/c9ob01161g  0.56
2019 van der Peet PL, Gunawan C, Watanabe M, Yamasaki S, Williams SJ. Correction to "Synthetic β-1,2-Mannosyloxymannitol Glycolipid from the Fungus Malassezia pachydermatis Signals through Human Mincle". The Journal of Organic Chemistry. PMID 31244087 DOI: 10.1021/acs.joc.9b01609  0.56
2019 van der Peet PL, Gunawan C, Watanabe M, Yamasaki S, Williams SJ. A synthetic β-1,2-mannosyloxymannitol glycolipid from the fungus Malassezia pachydermatis signals through human Mincle. The Journal of Organic Chemistry. PMID 31046282 DOI: 10.1021/acs.joc.9b00544  0.56
2019 Abayakoon P, Epa R, Petricevic M, Bengt C, Mui JW, van der Peet PL, Zhang Y, Lingford JP, White JM, Goddard-Borger ED, Williams SJ. Comprehensive synthesis of substrates, intermediates and products of the sulfoglycolytic Embden-Meyerhoff-Parnas pathway. The Journal of Organic Chemistry. PMID 30742766 DOI: 10.1021/acs.joc.9b00055  0.56
2019 van der Peet PL, Sandanayake S, Jarrott B, Williams SJ. Discovery of N-Aryloxypropylbenzylamines as Voltage-gated Sodium Channel NaV1.2 subtype Selective Inhibitors. Chemmedchem. PMID 30676691 DOI: 10.1002/cmdc.201800781  0.56
2018 Cartmell A, Muñoz-Muñoz J, Briggs JA, Ndeh DA, Lowe EC, Baslé A, Terrapon N, Stott K, Heunis T, Gray J, Yu L, Dupree P, Fernandes PZ, Shah S, Williams SJ, et al. A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation. Nature Microbiology. PMID 30349080 DOI: 10.1038/s41564-018-0258-8  0.56
2018 Abayakoon P, Jin Y, Lingford JP, Petricevic M, John A, Ryan E, Wai-Ying Mui J, Pires DEV, Ascher DB, Davies GJ, Goddard-Borger ED, Williams SJ. Structural and Biochemical Insights into the Function and Evolution of Sulfoquinovosidases. Acs Central Science. 4: 1266-1273. PMID 30276262 DOI: 10.1021/acscentsci.8b00453  0.56
2018 van der Peet PL, Gunawan C, Abdul-Ridha A, Ma S, Scott DJ, Gundlach AL, Bathgate RAD, White JM, Williams SJ. Gram scale preparation of clozapine -oxide (CNO), a synthetic small molecule actuator for muscarinic acetylcholine DREADDs. Methodsx. 5: 257-267. PMID 30038895 DOI: 10.1016/j.mex.2018.03.003  0.56
2018 Schröder SP, Kallemeijn WW, Debets MF, Sobala LF, Hakki Z, Williams SJ, Beenakker TJM, Aerts JMFG, van der Marel GA, Codée JDC, Davies GJ, Overkleeft HS. Spiro-epoxyglycosides as activity-based probes for glycoside hydrolase family 99 endomannosidase/endomannanase. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29797675 DOI: 10.1002/chem.201801902  0.56
2018 Thompson AJ, Spears RJ, Zhu Y, Suits MDL, Williams SJ, Gilbert HJ, Davies GJ. Bacteroides thetaiotaomicron generates diverse α-mannosidase activities through subtle evolution of a distal substrate-binding motif. Acta Crystallographica. Section D, Structural Biology. 74: 394-404. PMID 29717710 DOI: 10.1107/S2059798318002942  0.56
2018 Abayakoon P, Lingford JP, Jin Y, Bengt C, Davies GJ, Yao S, Goddard-Borger ED, Williams SJ. Discovery and characterization of a sulfoquinovose mutarotase using kinetic analysis at equilibrium by exchange spectroscopy. The Biochemical Journal. PMID 29535276 DOI: 10.1042/BCJ20170947  0.56
2018 Fernandes PZ, Petricevic M, Sobala L, Davies GJ, Williams SJ. Exploration of strategies for mechanism-based inhibitor design for family GH99 endo-α-1,2-mannanases. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29508463 DOI: 10.1002/chem.201800435  0.56
2017 Alhifthi A, Harris BL, Goerigk L, White JM, Williams SJ. Structure-reactivity correlations of the abnormal Beckmann reaction of dihydrolevoglucosenone oxime. Organic & Biomolecular Chemistry. PMID 29170781 DOI: 10.1039/c7ob02499a  0.56
2017 Bellmaine SF, Ovchinnikov DA, Manallack DT, Cuddy CE, Elefanty AG, Stanley EG, Wolvetang EJ, Williams SJ, Pera M. Inhibition of DYRK1A disrupts neural lineage specification in human pluripotent stem cells. Elife. 6. PMID 28884684 DOI: 10.7554/eLife.24502  0.36
2017 Burugupalli S, Richardson MB, Williams SJ. Total synthesis and mass spectrometric analysis of a Mycobacterium tuberculosis phosphatidylglycerol featuring a two-step synthesis of (R)-tuberculostearic acid. Organic & Biomolecular Chemistry. PMID 28831486 DOI: 10.1039/c7ob01786c  0.88
2017 Belz T, Jin Y, Coines J, Rovira C, Davies GJ, Williams SJ. An atypical interaction explains the high-affinity of a non-hydrolyzable S-linked 1,6-α-mannanase inhibitor. Chemical Communications (Cambridge, England). PMID 28766587 DOI: 10.1039/c7cc04977c  0.56
2017 Males A, Raich L, Williams SJ, Rovira C, Davies GJ. Conformational analysis of the mannosidase inhibitor kifunensine: a quantum mechanical and structural approach. Chembiochem : a European Journal of Chemical Biology. PMID 28493500 DOI: 10.1002/cbic.201700166  0.56
2017 Osburn S, Speciale G, Williams SJ, O'Hair RAJ. Gas-Phase Intercluster Thiyl-Radical Induced C-H Bond Homolysis Selectively Forms Sugar C2-Radical Cations of Methyl D-Glucopyranoside: Isotopic Labeling Studies and Cleavage Reactions. Journal of the American Society For Mass Spectrometry. PMID 28474266 DOI: 10.1007/s13361-017-1667-2  0.56
2017 Temple MJ, Cuskin F, Baslé A, Hickey N, Speciale G, Williams SJ, Gilbert HJ, Lowe EC. A Bacteroidetes locus dedicated to fungal 1,6-β-glucan degradation: unique substrate conformation drives specificity of the key endo-1,6-β-glucanase. The Journal of Biological Chemistry. PMID 28461332 DOI: 10.1074/jbc.M117.787606  0.56
2017 Kuribara T, Hirano M, Speciale G, Williams SJ, Ito Y, Totani K. Selective Manipulation of Discrete Mannosidase Activities in the Endoplasmic Reticulum by Using Reciprocally Selective Inhibitors. Chembiochem : a European Journal of Chemical Biology. PMID 28371030 DOI: 10.1002/cbic.201700081  0.56
2017 Goddard-Borger ED, Williams SJ. Sulfoquinovose in the biosphere: occurrence, metabolism and functions. The Biochemical Journal. 474: 827-849. PMID 28219973 DOI: 10.1042/BCJ20160508  0.44
2017 Richardson MB, Smith DG, Williams SJ. Quantitation in the regioselectivity of acylation of glycosyl diglycerides: total synthesis of a Streptococcus pneumoniae α-glucosyl diglyceride. Chemical Communications (Cambridge, England). PMID 28054047 DOI: 10.1039/c6cc09584d  0.88
2016 Jin Y, Petricevic M, John A, Raich L, Jenkins H, Portela De Souza L, Cuskin F, Gilbert HJ, Rovira C, Goddard-Borger ED, Williams SJ, Davies GJ. A β-Mannanase with a Lysozyme-like Fold and a Novel Molecular Catalytic Mechanism. Acs Central Science. 2: 896-903. PMID 28058278 DOI: 10.1021/acscentsci.6b00232  0.56
2016 Alonso-Gil S, Males A, Fernandes P, Williams SJ, Davies GJ, Rovira C. Computational design-of-experiment unveils the conformational reaction coordinate of GH125 α-mannosidases. Journal of the American Chemical Society. PMID 28026180 DOI: 10.1021/jacs.6b11247  0.56
2016 Petricevic M, Sobala LF, Fernandes P, Raich L, Thompson AJ, Bernardo-Seisdedos G, Millet O, Zhu S, Sollogoub M, Jimenez-Barbero J, Rovira C, Davies GJ, Williams SJ. Contribution of shape and charge to the inhibition of a family GH99 endo-α-1,2-mannanase. Journal of the American Chemical Society. PMID 27992199 DOI: 10.1021/jacs.6b10075  0.56
2016 Speciale G, Farren-Dai M, Shidmoossavee FS, Williams SJ, Bennet AJ. C2-Oxyanion neighboring group participation: Transition state structure for the hydroxide-promoted hydrolysis of 4-nitrophenyl α-D-mannopyranoside. Journal of the American Chemical Society. PMID 27723312 DOI: 10.1021/jacs.6b07935  0.56
2016 van der Peet PL, Nagata M, Shah S, White JM, Yamasaki S, Williams SJ. Lipid structure influences the ability of glucose monocorynomycolate to signal through Mincle. Organic & Biomolecular Chemistry. 14: 9267-9277. PMID 27714279 DOI: 10.1039/c6ob01781a  0.56
2016 Roth C, Petricevic M, John A, Goddard-Borger ED, Davies GJ, Williams SJ. Structural and mechanistic insights into a Bacteroides vulgatus retaining N-acetyl-β-galactosaminidase that uses neighbouring group participation. Chemical Communications (Cambridge, England). PMID 27546776 DOI: 10.1039/c6cc04649e  1
2016 Shah S, Nagata M, Yamasaki S, Williams SJ. Total synthesis of a cyclopropane-fatty acid α-glucosyl diglyceride from Lactobacillus plantarum and identification of its ability to signal through Mincle. Chemical Communications (Cambridge, England). PMID 27533919 DOI: 10.1039/c6cc05631h  0.56
2016 Sedger LM, Tull DL, McConville MJ, De Souza DP, Rupasinghe TW, Williams SJ, Dayalan S, Lanzer D, Mackie H, Lam TC, Boyages J. Lipidomic Profiling of Adipose Tissue Reveals an Inflammatory Signature in Cancer-Related and Primary Lymphedema. Plos One. 11: e0154650. PMID 27182733 DOI: 10.1371/journal.pone.0154650  1
2016 Belz T, Williams SJ. A building block approach to the synthesis of a family of S-linked α-1,6-oligomannosides. Carbohydrate Research. PMID 27129668 DOI: 10.1016/j.carres.2016.04.015  1
2016 Charoenwattanasatien R, Pengthaisong S, Breen I, Mutoh R, Sansenya S, Hua Y, Tankrathok A, Wu L, Songsiriritthigul C, Tanaka H, Williams SJ, Davies GJ, Kurisu G, Ketudat Cairns JR. Bacterial β-glucosidase reveals the structural and functional basis of genetic defects in human glucocerebrosidase 2 (GBA2). Acs Chemical Biology. PMID 27115290 DOI: 10.1021/acschembio.6b00192  1
2016 Speciale G, Jin Y, Davies GJ, Williams SJ, Goddard-Borger ED. YihQ is a sulfoquinovosidase that cleaves sulfoquinovosyl diacylglyceride sulfolipids. Nature Chemical Biology. PMID 26878550 DOI: 10.1038/nchembio.2023  1
2016 Davies GJ, Williams SJ. Carbohydrate-active enzymes: sequences, shapes, contortions and cells. Biochemical Society Transactions. 44: 79-87. PMID 26862192 DOI: 10.1042/BST20150186  1
2016 Thompson AJ, Speciale G, Iglesias-Fernández J, Hakki Z, Belz T, Cartmell A, Spears RJ, Chandler E, Temple MJ, Stepper J, Gilbert HJ, Rovira C, Williams SJ, Davies GJ. Corrigendum: Evidence for a Boat Conformation at the Transition State of GH76 α-1,6-Mannanases-Key Enzymes in Bacterial and Fungal Mannoprotein Metabolism. Angewandte Chemie (International Ed. in English). 55: 1949. PMID 26836331 DOI: 10.1002/anie.201511540  0.56
2015 Smith DG, Williams SJ. Immune sensing of microbial glycolipids and related conjugates by T cells and the pattern recognition receptors MCL and Mincle. Carbohydrate Research. 420: 32-45. PMID 26717547 DOI: 10.1016/j.carres.2015.11.009  1
2015 Burugupalli S, Shah S, van der Peet PL, Arora S, White JM, Williams SJ. Investigation of benzoyloximes as benzoylating reagents: benzoyl-Oxyma as a selective benzoylating reagent. Organic & Biomolecular Chemistry. PMID 26531176 DOI: 10.1039/c5ob02092a  1
2015 Cameron G, Pellicci DG, Uldrich AP, Besra GS, Illarionov P, Williams SJ, La Gruta NL, Rossjohn J, Godfrey DI. Antigen Specificity of Type I NKT Cells Is Governed by TCR β-Chain Diversity. Journal of Immunology (Baltimore, Md. : 1950). PMID 26423148 DOI: 10.4049/jimmunol.1501222  1
2015 Richardson MB, Torigoe S, Yamasaki S, Williams SJ. Mycobacterium tuberculosis β-gentiobiosyl diacylglycerides signal through the pattern recognition receptor Mincle: total synthesis and structure activity relationships. Chemical Communications (Cambridge, England). PMID 26310657 DOI: 10.1039/c5cc04773k  1
2015 Jarrott B, Williams SJ. Chronic Brain Inflammation: The Neurochemical Basis for Drugs to Reduce Inflammation. Neurochemical Research. PMID 26177578 DOI: 10.1007/s11064-015-1661-7  1
2015 Thompson AJ, Speciale G, Iglesias-Fernández J, Hakki Z, Belz T, Cartmell A, Spears RJ, Chandler E, Temple MJ, Stepper J, Gilbert HJ, Rovira C, Williams SJ, Davies GJ. Evidence for a boat conformation at the transition state of GH76 α-1,6-mannanases--key enzymes in bacterial and fungal mannoprotein metabolism. Angewandte Chemie (International Ed. in English). 54: 5378-82. PMID 25772148 DOI: 10.1002/anie.201410502  1
2015 Cuskin F, Lowe EC, Temple MJ, Zhu Y, Cameron EA, Pudlo NA, Porter NT, Urs K, Thompson AJ, Cartmell A, Rogowski A, Hamilton BS, Chen R, Tolbert TJ, Piens K, ... ... Williams SJ, et al. Corrigendum: Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism. Nature. 520: 388. PMID 25739504 DOI: 10.1038/nature14334  1
2015 van der Peet PL, Gunawan C, Torigoe S, Yamasaki S, Williams SJ. Corynomycolic acid-containing glycolipids signal through the pattern recognition receptor Mincle. Chemical Communications (Cambridge, England). 51: 5100-3. PMID 25714652 DOI: 10.1039/c5cc00085h  1
2015 Cuskin F, Lowe EC, Temple MJ, Zhu Y, Cameron EA, Pudlo NA, Porter NT, Urs K, Thompson AJ, Cartmell A, Rogowski A, Hamilton BS, Chen R, Tolbert TJ, Piens K, ... ... Williams SJ, et al. Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism. Nature. 517: 165-9. PMID 25567280 DOI: 10.1038/nature13995  1
2015 Hakki Z, Thompson AJ, Bellmaine S, Speciale G, Davies GJ, Williams SJ. Structural and kinetic dissection of the endo-α-1,2-mannanase activity of bacterial GH99 glycoside hydrolases from Bacteroides spp. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 1966-77. PMID 25487964 DOI: 10.1002/chem.201405539  1
2015 Yamaryo-Botte Y, Rainczuk AK, Lea-Smith DJ, Brammananth R, van der Peet PL, Meikle P, Ralton JE, Rupasinghe TW, Williams SJ, Coppel RL, Crellin PK, McConville MJ. Acetylation of trehalose mycolates is required for efficient MmpL-mediated membrane transport in Corynebacterineae. Acs Chemical Biology. 10: 734-46. PMID 25427102 DOI: 10.1021/cb5007689  1
2015 Agostino M, Velkov T, Dingjan T, Williams SJ, Yuriev E, Ramsland PA. The carbohydrate-binding promiscuity of Euonymus europaeus lectin is predicted to involve a single binding site. Glycobiology. 25: 101-14. PMID 25209582 DOI: 10.1093/glycob/cwu095  1
2015 Tankrathok A, Iglesias-Fernández J, Williams RJ, Pengthaisong S, Baiya S, Hakki Z, Robinson RC, Hrmova M, Rovira C, Williams SJ, Ketudat Cairns JR. A Single Glycosidase Harnesses Different Pyranoside Ring Transition State Conformations for Hydrolysis of Mannosides and Glucosides Acs Catalysis. 5: 6041-6051. DOI: 10.1021/acscatal.5b01547  1
2015 Osburn S, Williams SJ, O'Hair RAJ. Formation of sugar radical cations from collision-induced dissociation of non-covalent complexes with S-nitroso thiyl radical precursors International Journal of Mass Spectrometry. 378: 95-106. DOI: 10.1016/j.ijms.2014.07.020  1
2014 Holien JK, Gazina EV, Elliott RW, Jarrott B, Cameron CE, Williams SJ, Parker MW, Petrou S. Computational Analysis of Amiloride Analogue Inhibitors of Coxsackievirus B3 RNA Polymerase. Journal of Proteomics & Bioinformatics. 004. PMID 26491236 DOI: 10.4172/jpb.S9-004  0.48
2014 Scheller KJ, Williams SJ, Lawrence AJ, Jarrott B, Djouma E. An improved method to prepare an injectable microemulsion of the galanin-receptor 3 selective antagonist, SNAP 37889, using Kolliphor(®) HS 15. Methodsx. 1: 212-6. PMID 26150955 DOI: 10.1016/j.mex.2014.09.003  1
2014 Shah S, White JM, Williams SJ. Total syntheses of cis-cyclopropane fatty acids: dihydromalvalic acid, dihydrosterculic acid, lactobacillic acid, and 9,10-methylenehexadecanoic acid. Organic & Biomolecular Chemistry. 12: 9427-38. PMID 25321346 DOI: 10.1039/c4ob01863j  1
2014 Speciale G, Thompson AJ, Davies GJ, Williams SJ. Dissecting conformational contributions to glycosidase catalysis and inhibition. Current Opinion in Structural Biology. 28: 1-13. PMID 25016573 DOI: 10.1016/j.sbi.2014.06.003  1
2014 Richardson MB, Williams SJ. MCL and Mincle: C-Type Lectin Receptors That Sense Damaged Self and Pathogen-Associated Molecular Patterns. Frontiers in Immunology. 5: 288. PMID 25002863 DOI: 10.3389/fimmu.2014.00288  1
2014 Connell TU, Schieber C, Silvestri IP, White JM, Williams SJ, Donnelly PS. Copper and silver complexes of tris(triazole)amine and tris(benzimidazole)amine ligands: evidence that catalysis of an azide-alkyne cycloaddition ("click") reaction by a silver tris(triazole)amine complex arises from copper impurities. Inorganic Chemistry. 53: 6503-11. PMID 24949519 DOI: 10.1021/ic5008999  1
2014 Ash BL, Quach T, Williams SJ, Lawrence AJ, Djouma E. Galanin-3 receptor antagonism by SNAP 37889 reduces motivation to self-administer alcohol and attenuates cue-induced reinstatement of alcohol-seeking in iP rats. Journal of Pharmacological Sciences. 125: 211-6. PMID 24881957 DOI: DN/JST.JSTAGE/jphs/13221FP  1
2014 Williams SJ, Denehy E, Krenske EH. Experimental and theoretical insights into the mechanisms of sulfate and sulfamate ester hydrolysis and the end products of type I sulfatase inactivation by aryl sulfamates. The Journal of Organic Chemistry. 79: 1995-2005. PMID 24555731 DOI: 10.1021/jo4026513  1
2014 Williams RJ, Iglesias-Fernández J, Stepper J, Jackson A, Thompson AJ, Lowe EC, White JM, Gilbert HJ, Rovira C, Davies GJ, Williams SJ. Combined inhibitor free-energy landscape and structural analysis reports on the mannosidase conformational coordinate. Angewandte Chemie (International Ed. in English). 53: 1087-91. PMID 24339341 DOI: 10.1002/anie.201308334  1
2014 Coombe DR, Davis C, Fincher G, McConville MJ, Packer N, Stubbs KA, Williams SJ, Dell A. Letter to the glycoforum transforming glycoscience: an Australian perspective. Glycobiology. 24: 1-3. PMID 24319023 DOI: 10.1093/glycob/cwt103  1
2013 Williams SJ, Zammit SC, Cox AJ, Shackleford DM, Morizzi J, Zhang Y, Powell AK, Gilbert RE, Krum H, Kelly DJ. 3',4'-Bis-difluoromethoxycinnamoylanthranilate (FT061): an orally-active antifibrotic agent that reduces albuminuria in a rat model of progressive diabetic nephropathy. Bioorganic & Medicinal Chemistry Letters. 23: 6868-73. PMID 24169234 DOI: 10.1016/j.bmcl.2013.09.100  1
2013 Richardson MB, Williams SJ. A practical synthesis of long-chain iso-fatty acids (iso-C12-C19) and related natural products. Beilstein Journal of Organic Chemistry. 9: 1807-12. PMID 24062846 DOI: 10.3762/bjoc.9.210  1
2013 Lim NR, Thomas CJ, Silva LS, Yeap YY, Yap S, Bell JR, Delbridge LM, Bogoyevitch MA, Woodman OL, Williams SJ, May CN, Ng DC. Cardioprotective 3',4'-dihydroxyflavonol attenuation of JNK and p38(MAPK) signalling involves CaMKII inhibition. The Biochemical Journal. 456: 149-61. PMID 24032640 DOI: 10.1042/BJ20121538  1
2013 van der Peet PL, Connell TU, Gunawan C, White JM, Donnelly PS, Williams SJ. A click chemistry approach to 5,5'-disubstituted-3,3'-bisisoxazoles from dichloroglyoxime and alkynes: luminescent organometallic iridium and rhenium bisisoxazole complexes. The Journal of Organic Chemistry. 78: 7298-304. PMID 23777255 DOI: 10.1021/jo4008755  1
2013 Alonzi DS, Kukushkin NV, Allman SA, Hakki Z, Williams SJ, Pierce L, Dwek RA, Butters TD. Glycoprotein misfolding in the endoplasmic reticulum: identification of released oligosaccharides reveals a second ER-associated degradation pathway for Golgi-retrieved proteins. Cellular and Molecular Life Sciences : Cmls. 70: 2799-814. PMID 23503623 DOI: 10.1007/s00018-013-1304-6  1
2013 Connell TU, Sandanayake S, Khairallah GN, White JM, O'Hair RA, Donnelly PS, Williams SJ. Halide-ion-templated Ag8Cu6 rhombic dodecahedrons: synthesis, structure and reactivity of [Ag8Cu6(C≡CtBu)12X]BF4 (X = Cl, Br). Dalton Transactions (Cambridge, England : 2003). 42: 4903-7. PMID 23377186 DOI: 10.1039/c3dt33027c  1
2013 Cao B, Chen X, Yamaryo-Botte Y, Richardson MB, Martin KL, Khairallah GN, Rupasinghe TW, O'Flaherty RM, O'Hair RA, Ralton JE, Crellin PK, Coppel RL, McConville MJ, Williams SJ. Synthesis, structural elucidation, and biochemical analysis of immunoactive glucuronosyl diacylglycerides of mycobacteria and corynebacteria. The Journal of Organic Chemistry. 78: 2175-90. PMID 23343519 DOI: 10.1021/jo302508e  1
2013 Zhang Y, Elsik M, Edgley AJ, Cox AJ, Kompa AR, Wang B, Tan CY, Khong FL, Stapleton DI, Zammit S, Williams SJ, Gilbert RE, Krum H, Kelly DJ. A new anti-fibrotic drug attenuates cardiac remodeling and systolic dysfunction following experimental myocardial infarction. International Journal of Cardiology. 168: 1174-85. PMID 23219315 DOI: 10.1016/j.ijcard.2012.11.067  1
2013 Williams SJ. Sulfatase inhibitors: a patent review. Expert Opinion On Therapeutic Patents. 23: 79-98. PMID 23136854 DOI: 10.1517/13543776.2013.736965  1
2012 Gilbert RE, Zhang Y, Williams SJ, Zammit SC, Stapleton DI, Cox AJ, Krum H, Langham R, Kelly DJ. A purpose-synthesised anti-fibrotic agent attenuates experimental kidney diseases in the rat. Plos One. 7: e47160. PMID 23071743 DOI: 10.1371/journal.pone.0047160  1
2012 Thompson AJ, Dabin J, Iglesias-Fernández J, Ardèvol A, Dinev Z, Williams SJ, Bande O, Siriwardena A, Moreland C, Hu TC, Smith DK, Gilbert HJ, Rovira C, Davies GJ. The reaction coordinate of a bacterial GH47 α-mannosidase: a combined quantum mechanical and structural approach. Angewandte Chemie (International Ed. in English). 51: 10997-1001. PMID 23012075 DOI: 10.1002/anie.201205338  1
2012 Schieber C, Bestetti A, Lim JP, Ryan AD, Nguyen TL, Eldridge R, White AR, Gleeson PA, Donnelly PS, Williams SJ, Mulvaney P. Conjugation of transferrin to azide-modified CdSe/ZnS core-shell quantum dots using cyclooctyne click chemistry. Angewandte Chemie (International Ed. in English). 51: 10523-7. PMID 22996637 DOI: 10.1002/anie.201202876  1
2012 Heskes AM, Goodger JQ, Tsegay S, Quach T, Williams SJ, Woodrow IE. Localization of oleuropeyl glucose esters and a flavanone to secretory cavities of Myrtaceae. Plos One. 7: e40856. PMID 22911712 DOI: 10.1371/journal.pone.0040856  1
2012 Tsegay S, Williams RJ, Williams SJ. Synthesis of glycosyl fluorides from thio-, seleno-, and telluroglycosides and glycosyl sulfoxides using aminodifluorosulfinium tetrafluoroborates. Carbohydrate Research. 357: 16-22. PMID 22682311 DOI: 10.1016/j.carres.2012.04.016  1
2012 Tan SM, Zhang Y, Wang B, Tan CY, Zammit SC, Williams SJ, Krum H, Kelly DJ. FT23, an orally active antifibrotic compound, attenuates structural and functional abnormalities in an experimental model of diabetic cardiomyopathy. Clinical and Experimental Pharmacology & Physiology. 39: 650-6. PMID 22612418 DOI: 10.1111/j.1440-1681.2012.05726.x  1
2012 Zhang Y, Edgley AJ, Cox AJ, Powell AK, Wang B, Kompa AR, Stapleton DI, Zammit SC, Williams SJ, Krum H, Gilbert RE, Kelly DJ. FT011, a new anti-fibrotic drug, attenuates fibrosis and chronic heart failure in experimental diabetic cardiomyopathy. European Journal of Heart Failure. 14: 549-62. PMID 22417655 DOI: 10.1093/eurjhf/hfs011  1
2012 van der Peet P, Ralton JE, McConville MJ, Williams SJ. Discovery of inhibitors of Leishmania β-1,2-mannosyltransferases using a click-chemistry-derived guanosine monophosphate library. Plos One. 7: e32642. PMID 22393429 DOI: 10.1371/journal.pone.0032642  1
2012 Tilley AJ, Zanatta SD, Qin CX, Kim IK, Seok YM, Stewart A, Woodman OL, Williams SJ. 2-Morpholinoisoflav-3-enes as flexible intermediates in the synthesis of phenoxodiol, isophenoxodiol, equol and analogues: vasorelaxant properties, estrogen receptor binding and Rho/RhoA kinase pathway inhibition. Bioorganic & Medicinal Chemistry. 20: 2353-61. PMID 22377671 DOI: 10.1016/j.bmc.2012.02.008  1
2012 Thompson AJ, Williams RJ, Hakki Z, Alonzi DS, Wennekes T, Gloster TM, Songsrirote K, Thomas-Oates JE, Wrodnigg TM, Spreitz J, Stütz AE, Butters TD, Williams SJ, Davies GJ. Structural and mechanistic insight into N-glycan processing by endo-α-mannosidase. Proceedings of the National Academy of Sciences of the United States of America. 109: 781-6. PMID 22219371 DOI: 10.1073/pnas.1111482109  1
2012 Kim HY, Seok YM, Woodman OL, Williams SJ, Kim IK. 3',4'-Dihydroxyflavonol reduces vascular contraction through Ca²⁺ desensitization in permeabilized rat mesenteric artery. Naunyn-Schmiedeberg's Archives of Pharmacology. 385: 191-202. PMID 21993847 DOI: 10.1007/s00210-011-0697-8  1
2012 Quach T, Tsegay S, Thompson AJ, Kukushkin NV, Alonzi DS, Butters TD, Davies GJ, Williams SJ. Fleetamine (3-O-α-d-glucopyranosyl-swainsonine): The synthesis of a hypothetical inhibitor of endo-α-mannosidase Tetrahedron Asymmetry. 23: 992-997. DOI: 10.1016/j.tetasy.2012.06.011  1
2011 Qin CX, Williams SJ, Woodman OL. Antioxidant activity contributes to flavonol cardioprotection during reperfusion of rat hearts. Free Radical Biology & Medicine. 51: 1437-44. PMID 21801832 DOI: 10.1016/j.freeradbiomed.2011.07.003  1
2011 Proietti Silvestri I, Andemarian F, Khairallah GN, Yap SW, Quach T, Tsegay S, Williams CM, O'Hair RA, Donnelly PS, Williams SJ. Copper(I)-catalyzed cycloaddition of silver acetylides and azides: incorporation of volatile acetylenes into the triazole core. Organic & Biomolecular Chemistry. 9: 6082-8. PMID 21748192 DOI: 10.1039/c1ob05360d  1
2011 Uldrich AP, Patel O, Cameron G, Pellicci DG, Day EB, Sullivan LC, Kyparissoudis K, Kjer-Nielsen L, Vivian JP, Cao B, Brooks AG, Williams SJ, Illarionov P, Besra GS, Turner SJ, et al. A semi-invariant Vα10+ T cell antigen receptor defines a population of natural killer T cells with distinct glycolipid antigen-recognition properties. Nature Immunology. 12: 616-23. PMID 21666690 DOI: 10.1038/ni.2051  1
2011 Cao B, White JM, Williams SJ. Synthesis of glycoconjugate fragments of mycobacterial phosphatidylinositol mannosides and lipomannan. Beilstein Journal of Organic Chemistry. 7: 369-77. PMID 21512604 DOI: 10.3762/bjoc.7.47  1
2011 Yap S, Woodman OL, Crack PJ, Williams SJ. Synthesis of a hypoxia-targeted conjugate of the cardioprotective agent 3',4'-dihydroxyflavonol and evaluation of its ability to reduce ischaemia/reperfusion injury. Bioorganic & Medicinal Chemistry Letters. 21: 5102-6. PMID 21470863 DOI: 10.1016/j.bmcl.2011.03.040  1
2011 Ash BL, Zanatta SD, Williams SJ, Lawrence AJ, Djouma E. The galanin-3 receptor antagonist, SNAP 37889, reduces operant responding for ethanol in alcohol-preferring rats. Regulatory Peptides. 166: 59-67. PMID 20736033 DOI: 10.1016/j.regpep.2010.08.009  1
2011 Williams SJ, Thomas CJ, Boujaoude M, Gannon CT, Zanatta SD, Jarrott B, May CN, Woodman OL. Water soluble flavonol prodrugs that protect against ischaemia-reperfusion injury in rat hindlimb and sheep heart Medchemcomm. 2: 321-324. DOI: 10.1039/c0md00240b  1
2011 Chen X, Khairallah GN, O'Hair RAJ, Williams SJ. Fixed-charge labels for simplified reaction analysis: 5-hydroxy-1,2,3- triazoles as byproducts of a copper(I)-catalyzed click reaction Tetrahedron Letters. 52: 2750-2753. DOI: 10.1016/j.tetlet.2011.03.094  1
2010 Gao X, Williams SJ, Woodman OL, Marriott PJ. Comprehensive two-dimensional gas chromatography, retention indices and time-of-flight mass spectra of flavonoids and chalcones. Journal of Chromatography. A. 1217: 8317-26. PMID 21094947 DOI: 10.1016/j.chroma.2010.10.093  1
2010 Hakki Z, Cao B, Heskes AM, Goodger JQ, Woodrow IE, Williams SJ. Synthesis of the monoterpenoid esters cypellocarpin C and cuniloside B and evidence for their widespread occurrence in Eucalyptus. Carbohydrate Research. 345: 2079-84. PMID 20708173 DOI: 10.1016/j.carres.2010.07.029  1
2010 Cao B, Williams SJ. Chemical approaches for the study of the mycobacterial glycolipids phosphatidylinositol mannosides, lipomannan and lipoarabinomannan. Natural Product Reports. 27: 919-47. PMID 20393651 DOI: 10.1039/c000604a  1
2010 Song MJ, Baek I, Seo M, Kim SH, Suk K, Woodman OL, Williams SJ, Kim IK. Effects of 3',4'-dihydroxyflavonol on vascular contractions of rat aortic rings. Clinical and Experimental Pharmacology & Physiology. 37: 803-10. PMID 20374259 DOI: 10.1111/j.1440-1681.2010.05384.x  1
2010 Zhu Y, Suits MD, Thompson AJ, Chavan S, Dinev Z, Dumon C, Smith N, Moremen KW, Xiang Y, Siriwardena A, Williams SJ, Gilbert HJ, Davies GJ. Mechanistic insights into a Ca2+-dependent family of alpha-mannosidases in a human gut symbiont. Nature Chemical Biology. 6: 125-32. PMID 20081828 DOI: 10.1038/nchembio.278  1
2010 Williams RJ, McGill NW, White JM, Williams SJ. Neighboring group participation in glycosylation reactions by 2,6-disubstituted 2-O-benzoyl groups: A mechanistic investigation Journal of Carbohydrate Chemistry. 29: 236-263. DOI: 10.1080/07328303.2010.508141  1
2010 Zanatta SD, Jarrott B, Williams SJ. Synthesis and preliminary pharmacological evaluation of aryl dithiolethiones with cyclooxygenase-2-selective inhibitory activity and hydrogen sulfide-releasing properties Australian Journal of Chemistry. 63: 946-957. DOI: 10.1071/CH09517  1
2010 Shirbin SJ, Boughton BA, Zammit SC, Zanatta SD, Marcuccio SM, Hutton CA, Williams SJ. Copper-free palladium-catalyzed Sonogashira and Hiyama cross-couplings using aryl imidazol-1-ylsulfonates Tetrahedron Letters. 51: 2971-2974. DOI: 10.1016/j.tetlet.2010.03.110  1
2009 McGill NW, Williams SJ. 2,6-Disubstituted benzoates as neighboring groups for enhanced diastereoselectivity in beta-galactosylation reactions: synthesis of beta-1,3-linked oligogalactosides related to arabinogalactan proteins. The Journal of Organic Chemistry. 74: 9388-98. PMID 19928755 DOI: 10.1021/jo902100q  1
2009 Zammit SC, Cox AJ, Gow RM, Zhang Y, Gilbert RE, Krum H, Kelly DJ, Williams SJ. Evaluation and optimization of antifibrotic activity of cinnamoyl anthranilates. Bioorganic & Medicinal Chemistry Letters. 19: 7003-6. PMID 19879136 DOI: 10.1016/j.bmcl.2009.09.120  1
2009 Goodger JQ, Cao B, Jayadi I, Williams SJ, Woodrow IE. Non-volatile components of the essential oil secretory cavities of Eucalyptus leaves: discovery of two glucose monoterpene esters, cuniloside B and froggattiside A. Phytochemistry. 70: 1187-94. PMID 19604527 DOI: 10.1016/j.phytochem.2009.06.004  1
2009 Loft KJ, Bojarová P, Slámová K, Kren V, Williams SJ. Synthesis of sulfated glucosaminides for profiling substrate specificities of sulfatases and fungal beta-N-acetylhexosaminidases. Chembiochem : a European Journal of Chemical Biology. 10: 565-76. PMID 19156788 DOI: 10.1002/cbic.200800656  1
2009 Bojarová P, Williams SJ. Aryl sulfamates are broad spectrum inactivators of sulfatases: effects on sulfatases from various sources. Bioorganic & Medicinal Chemistry Letters. 19: 477-80. PMID 19058962 DOI: 10.1016/j.bmcl.2008.11.059  1
2009 Zanatta SD, Manallack DT, Jarrott B, Williams SJ. Synthesis and evaluation of dithiolethiones as novel cyclooxygenase inhibitors. Bioorganic & Medicinal Chemistry Letters. 19: 459-61. PMID 19056264 DOI: 10.1016/j.bmcl.2008.11.045  1
2009 Williams SJ. Robert Vyent Stick: A colourful character Australian Journal of Chemistry. 62: 503-509. DOI: 10.1071/CH09047  1
2008 Yap S, Loft KJ, Woodman OL, Williams SJ. Discovery of water-soluble antioxidant flavonols without vasorelaxant activity. Chemmedchem. 3: 1572-9. PMID 18756557 DOI: 10.1002/cmdc.200800146  1
2008 Bojarová P, Williams SJ. Sulfotransferases, sulfatases and formylglycine-generating enzymes: a sulfation fascination. Current Opinion in Chemical Biology. 12: 573-81. PMID 18625336 DOI: 10.1016/j.cbpa.2008.06.018  1
2008 Donnelly PS, Zanatta SD, Zammit SC, White JM, Williams SJ. 'Click' cycloaddition catalysts: copper(I) and copper(II) tris(triazolylmethyl)amine complexes. Chemical Communications (Cambridge, England). 2459-61. PMID 18491014 DOI: 10.1039/b719724a  1
2008 Qin CX, Chen X, Hughes RA, Williams SJ, Woodman OL. Understanding the cardioprotective effects of flavonols: discovery of relaxant flavonols without antioxidant activity. Journal of Medicinal Chemistry. 51: 1874-84. PMID 18307286 DOI: 10.1021/jm070352h  1
2008 Bojarová P, Denehy E, Walker I, Loft K, De Souza DP, Woo LW, Potter BV, McConville MJ, Williams SJ. Direct evidence for ArO-S bond cleavage upon inactivation of Pseudomonas aeruginosa arylsulfatase by aryl sulfamates. Chembiochem : a European Journal of Chemical Biology. 9: 613-23. PMID 18288656 DOI: 10.1002/cbic.200700579  1
2008 Watt JA, Gannon CT, Loft KJ, Dinev Z, Williams SJ. 'Click' preparation of carbohydrate 1-benzotriazoles, 1,4-disubstituted, and 1,4,5-trisubstituted triazoles and their utility as glycosyl donors Australian Journal of Chemistry. 61: 837-846. DOI: 10.1071/CH08364  1
2007 Denehy E, White JM, Williams SJ. Electronic structure of the sulfonyl and phosphonyl groups: a computational and crystallographic study. Inorganic Chemistry. 46: 8871-86. PMID 17880060 DOI: 10.1021/ic700687t  1
2007 Wicki J, Williams SJ, Withers SG. Transition-state mimicry by glycosidase inhibitors: a critical kinetic analysis. Journal of the American Chemical Society. 129: 4530-1. PMID 17385869 DOI: 10.1021/ja0707254  1
2007 Senaratne RH, Mougous JD, Reader JR, Williams SJ, Zhang T, Bertozzi CR, Riley LW. Vaccine efficacy of an attenuated but persistent Mycobacterium tuberculosis cysH mutant. Journal of Medical Microbiology. 56: 454-8. PMID 17374883 DOI: 10.1099/jmm.0.46983-0  1
2007 Dinev Z, Gannon CT, Egan C, Watt JA, McConville MJ, Williams SJ. Galactose-derived phosphonate analogues as potential inhibitors of phosphatidylinositol biosynthesis in mycobacteria. Organic & Biomolecular Chemistry. 5: 952-9. PMID 17340011 DOI: 10.1039/b616450a  1
2006 van der Peet P, Gannon CT, Walker I, Dinev Z, Angelin M, Tam S, Ralton JE, McConville MJ, Williams SJ. Use of click chemistry to define the substrate specificity of Leishmania beta-1,2-mannosyltransferases. Chembiochem : a European Journal of Chemical Biology. 7: 1384-91. PMID 16841351 DOI: 10.1002/cbic.200600159  1
2006 Sernee MF, Ralton JE, Dinev Z, Khairallah GN, O'Hair RA, Williams SJ, McConville MJ. Leishmania beta-1,2-mannan is assembled on a mannose-cyclic phosphate primer. Proceedings of the National Academy of Sciences of the United States of America. 103: 9458-63. PMID 16766650 DOI: 10.1073/pnas.0603539103  1
2006 Dinev Z, Wardak AZ, Brownlee RT, Williams SJ. A convenient gram-scale synthesis of uridine diphospho(13C6)glucose. Carbohydrate Research. 341: 1743-7. PMID 16603138 DOI: 10.1016/j.carres.2006.02.033  1
2006 Senaratne RH, De Silva AD, Williams SJ, Mougous JD, Reader JR, Zhang T, Chan S, Sidders B, Lee DH, Chan J, Bertozzi CR, Riley LW. 5'-Adenosinephosphosulphate reductase (CysH) protects Mycobacterium tuberculosis against free radicals during chronic infection phase in mice. Molecular Microbiology. 59: 1744-53. PMID 16553880 DOI: 10.1111/j.1365-2958.2006.05075.x  1
2006 Williams SJ, Hekmat O, Withers SG. Synthesis and testing of mechanism-based protein-profiling probes for retaining endo-glycosidases. Chembiochem : a European Journal of Chemical Biology. 7: 116-24. PMID 16397879 DOI: 10.1002/cbic.200500279  1
2006 Denehy E, White JM, Williams SJ. Ground state structures of sulfate monoesters and sulfamates reveal similar reaction coordinates for sulfuryl and sulfamyl transfer. Chemical Communications (Cambridge, England). 314-6. PMID 16391745 DOI: 10.1039/b513712h  1
2005 Hekmat O, Kim YW, Williams SJ, He S, Withers SG. Active-site peptide "fingerprinting" of glycosidases in complex mixtures by mass spectrometry. Discovery of a novel retaining beta-1,4-glycanase in Cellulomonas fimi. The Journal of Biological Chemistry. 280: 35126-35. PMID 16085650 DOI: 10.1074/jbc.M508434200  1
2005 Watt JA, Williams SJ. Rapid, iterative assembly of octyl alpha-1,6-oligomannosides and their 6-deoxy equivalents. Organic & Biomolecular Chemistry. 3: 1982-92. PMID 15889182 DOI: 10.1039/b503919c  1
2005 Morita YS, Velasquez R, Taig E, Waller RF, Patterson JH, Tull D, Williams SJ, Billman-Jacobe H, McConville MJ. Compartmentalization of lipid biosynthesis in mycobacteria. The Journal of Biological Chemistry. 280: 21645-52. PMID 15805104 DOI: 10.1074/jbc.M414181200  1
2004 Gloster TM, Williams SJ, Roberts S, Tarling CA, Wicki J, Withers SG, Davies GJ. Atomic resolution analyses of the binding of xylobiose-derived deoxynojirimycin and isofagomine to xylanase Xyn10A. Chemical Communications (Cambridge, England). 1794-5. PMID 15306887 DOI: 10.1039/b405152a  1
2004 Williams SJ, Davies GJ. A master of its sulfate. Nature Structural & Molecular Biology. 11: 686-7. PMID 15280877 DOI: 10.1038/nsmb0804-686  1
2004 Woodruff PJ, Carlson BL, Siridechadilok B, Pratt MR, Senaratne RH, Mougous JD, Riley LW, Williams SJ, Bertozzi CR. Trehalose is required for growth of Mycobacterium smegmatis. The Journal of Biological Chemistry. 279: 28835-43. PMID 15102847 DOI: 10.1074/jbc.M313103200  1
2003 Gloster T, Williams SJ, Tarling CA, Roberts S, Dupont C, Jodoin P, Shareck F, Withers SG, Davies GJ. A xylobiose-derived isofagomine lactam glycosidase inhibitor binds as its amide tautomer. Chemical Communications (Cambridge, England). 944-5. PMID 12744311  1
2003 Williams SJ, Best JD. Novel microsomal triglyceride transfer protein inhibitors Expert Opinion On Therapeutic Patents. 13: 479-488. DOI: 10.1517/13543776.13.4.479  1
2002 Mougous JD, Leavell MD, Senaratne RH, Leigh CD, Williams SJ, Riley LW, Leary JA, Bertozzi CR. Discovery of sulfated metabolites in mycobacteria with a genetic and mass spectrometric approach. Proceedings of the National Academy of Sciences of the United States of America. 99: 17037-42. PMID 12482950 DOI: 10.1073/pnas.252514899  1
2002 Williams SJ, Mark BL, Vocadlo DJ, James MN, Withers SG. Aspartate 313 in the Streptomyces plicatus hexosaminidase plays a critical role in substrate-assisted catalysis by orienting the 2-acetamido group and stabilizing the transition state. The Journal of Biological Chemistry. 277: 40055-65. PMID 12171933 DOI: 10.1074/jbc.M206481200  1
2002 Mougous JD, Green RE, Williams SJ, Brenner SE, Bertozzi CR. Sulfotransferases and sulfatases in mycobacteria. Chemistry & Biology. 9: 767-76. PMID 12144918 DOI: 10.1016/S1074-5521(02)00175-8  1
2002 Williams SJ, Senaratne RH, Mougous JD, Riley LW, Bertozzi CR. 5'-adenosinephosphosulfate lies at a metabolic branch point in mycobacteria. The Journal of Biological Chemistry. 277: 32606-15. PMID 12072441 DOI: 10.1074/jbc.M204613200  1
2002 Notenboom V, Boraston AB, Williams SJ, Kilburn DG, Rose DR. High-resolution crystal structures of the lectin-like xylan binding domain from Streptomyces lividans xylanase 10A with bound substrates reveal a novel mode of xylan binding. Biochemistry. 41: 4246-54. PMID 11914070 DOI: 10.1021/bi015865j  1
2002 Leavell MD, Mougous JD, Senaratne RH, Leigh C, Williams SJ, Riley L, Bertozzi CR, Leary JA. Strategy for the identification of sulfated metabolites in bacterial cell extracts using FT-ICR, isotopic labeling and genetics Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 415-416.  1
2000 Notenboom V, Williams SJ, Hoos R, Withers SG, Rose DR. Detailed structural analysis of glycosidase/inhibitor interactions: complexes of Cex from Cellulomonas fimi with xylobiose-derived aza-sugars. Biochemistry. 39: 11553-63. PMID 10995222  0.88
2000 Williams SJ, Withers SG. Glycosyl fluorides in enzymatic reactions. Carbohydrate Research. 327: 27-46. PMID 10968675 DOI: 10.1016/S0008-6215(00)00041-0  1
1997 Stick RV, Matthew D, Tilbrook G, Williams SJ. 1,6-epithio- and 1,6-episeleno-β-D-glucopyranose: Useful Adjuncts in the synthesis of 6-deoxy-β-D-glucopyranosides Tetrahedron Letters. 38: 2741-2744. DOI: 10.1016/S0040-4039(97)00458-9  1
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