Daniel Romo, Ph.D. - Publications

1993-2015 Chemistry Texas A & M University, College Station, TX, United States 
 2015- Baylor University, Waco, TX 
Natural Product Synthesis, Organic Chemistry

141 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Naineni SK, Liang J, Hull K, Cencic R, Zhu M, Northcote P, Teesdale-Spittle P, Romo D, Nagar B, Pelletier J. Functional mimicry revealed by the crystal structure of an eIF4A:RNA complex bound to the interfacial inhibitor, desmethyl pateamine A. Cell Chemical Biology. PMID 33412110 DOI: 10.1016/j.chembiol.2020.12.006  0.76
2020 El Atab O, Darwiche R, Truax NJ, Schneiter R, Hull KG, Romo D, Asojo OA. Secreted Protein-2 (-ASP-2) Binds an Ascaroside (ascr#3) in Its Fatty Acid Binding Site. Frontiers in Chemistry. 8: 608296. PMID 33392151 DOI: 10.3389/fchem.2020.608296  0.76
2020 Chaheine CM, Gladen PT, Abbasov ME, Romo D. Enantioselective, Organocatalytic Strategy for the Oxazolomycin Core: Formal Synthesis of (+)-Neooxazolomycin. Organic Letters. PMID 33226820 DOI: 10.1021/acs.orglett.0c03511  1
2020 Tong L, Zhao Q, Datan E, Lin GQ, Minn I, Pomper MG, Yu B, Romo D, He QL, Liu JO. Triptolide: reflections on two decades of research and prospects for the future. Natural Product Reports. PMID 33146205 DOI: 10.1039/d0np00054j  1
2020 Truax NJ, Romo D. Bridging the gap between natural product synthesis and drug discovery. Natural Product Reports. PMID 33104139 DOI: 10.1039/d0np00048e  0.76
2020 Tao Y, Reisenauer KN, Masi M, Evidente A, Taube JH, Romo D. Pharmacophore-Directed Retrosynthesis Applied to Ophiobolin A: Simplified Bicyclic Derivatives Displaying Anticancer Activity. Organic Letters. PMID 33034457 DOI: 10.1021/acs.orglett.0c02938  0.36
2020 Sun HS, Horgen FD, Romo D, Hull KG, Kiledal SA, Fleig A, Feng ZP. Waixenicin A, a marine-derived TRPM7 inhibitor: a promising CNS drug lead. Acta Pharmacologica Sinica. PMID 32994545 DOI: 10.1038/s41401-020-00512-4  0.36
2020 Chow S, Krainz T, Bettencourt CJ, Broit N, Ferguson B, Zhu M, Hull KG, Pierens GK, Bernhardt PV, Parsons PG, Romo D, Boyle GM, Williams CM. Synthetic Tigliane Intermediates Engage Thiols to Induce Potent Cell Line Selective Anti-Cancer Activity. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32991008 DOI: 10.1002/chem.202003221  0.76
2020 Rao Kovvuri VR, Xue H, Romo D. Generation and Reactivity of 2-Amido-1,3-diaminoallyl Cations: Cyclic Guanidine Annulations via Net (3 + 2) and (4 + 3) Cycloadditions. Organic Letters. PMID 32009413 DOI: 10.1021/acs.orglett.0c00019  0.56
2020 Kommaraju SS, Aulicino J, Gobbooru S, Li J, Zhu M, Romo D, Low WK. Investigation of the mechanism of action of a potent pateamine A analog, des-methyl, des-amino pateamine A (DMDAPatA). Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. PMID 32008367 DOI: 10.1139/bcb-2019-0307  0.76
2020 Adedoja AN, McMahan T, Neal JP, Hamal Dhakal S, Jois S, Romo D, Hull K, Garlapati S. Translation initiation factors GleIF4E2 and GleIF4A can interact directly with the components of the pre-initiation complex to facilitate translation initiation in Giardia lamblia. Molecular and Biochemical Parasitology. 111258. PMID 31968220 DOI: 10.1016/j.molbiopara.2020.111258  0.76
2019 Orr AA, Yang J, Sule N, Chawla R, Hull KG, Zhu M, Romo D, Lele PP, Jayaraman A, Manson MD, Tamamis P. Molecular Mechanism for Attractant Signaling to DHMA by E. coli Tsr. Biophysical Journal. PMID 31839263 DOI: 10.1016/j.bpj.2019.11.3382  0.96
2019 Truax NJ, Ayinde S, Van K, Liu JO, Romo D. Pharmacophore-Directed Retrosynthesis Applied to Rameswaralide: Synthesis and Bioactivity of Natural Product Tricyclic Cores. Organic Letters. PMID 31498642 DOI: 10.1021/acs.orglett.9b02713  1
2019 Alvariño R, Alonso E, Abbasov ME, Chaheine CM, Conner ML, Romo D, Alfonso A, Botana LM. Gracilin A derivatives target early events in Alzheimer's disease: effects on neuroinflammation and oxidative stress. Acs Chemical Neuroscience. PMID 31387354 DOI: 10.1021/acschemneuro.9b00329  1
2019 Abbasov ME, Alvariño R, Chaheine CM, Alonso E, Sánchez JA, Conner ML, Alfonso A, Jaspars M, Botana LM, Romo D. Simplified immunosuppressive and neuroprotective agents based on gracilin A. Nature Chemistry. 11: 342-350. PMID 30903037 DOI: 10.1038/s41557-019-0230-0  1
2019 Chen R, Zhu M, Chaudhari RR, Robles O, Chen Y, Skillern W, Qin Q, Wierda WG, Zhang S, Hull KG, Romo D, Plunkett W. Creating novel translation inhibitors to target pro-survival proteins in chronic lymphocytic leukemia. Leukemia. PMID 30700841 DOI: 10.1038/s41375-018-0364-x  0.76
2019 Romo D, Tao Y, Reisenauer K, Taube JH. Total Synthesis and Anticancer Activity of (+)-Hypercalin C and Congeners. Angewandte Chemie (International Ed. in English). PMID 30600887 DOI: 10.1002/anie.201812909  0.36
2018 Ravichandran A, Geng M, Hull KG, Li J, Romo D, Lu SE, Albee A, Nutter C, Gordon DM, Ghannoum MA, Lockless SW, Smith L. A Novel Actin Binding Drug with Efficacy. Antimicrobial Agents and Chemotherapy. PMID 30323040 DOI: 10.1128/AAC.01585-18  0.76
2018 Groll M, Nguyen H, Vellalath S, Romo D. (-)-Homosalinosporamide A and Its Mode of Proteasome Inhibition: An X-ray Crystallographic Study. Marine Drugs. 16. PMID 30029468 DOI: 10.3390/md16070240  0.88
2018 Odokonyero D, McMillan AW, Ramagopal UA, Toro R, Truong DP, Zhu M, Lopez MS, Somiari B, Herman M, Aziz A, Bonanno JB, Hull KG, Burley SK, Romo D, Almo SC, et al. Comparison of Alicyclobacillus acidocaldarius OSBS to its promiscuous NSAR/OSBS relatives. Biochemistry. PMID 29767960 DOI: 10.1021/acs.biochem.8b00088  0.76
2017 Van KN, Romo D. Multicomponent, Enantioselective Michael-Michael-Aldol-β-Lactonizations Delivering Complex β-Lactones. The Journal of Organic Chemistry. PMID 29219311 DOI: 10.1021/acs.joc.7b02543  0.8
2017 Wright MH, Tao Y, Drechsel J, Krysiak J, Chamni S, Weigert-Munoz A, Harvey NL, Romo D, Sieber SA. Quantitative chemoproteomic profiling reveals multiple target interactions of spongiolactone derivatives in leukemia cells. Chemical Communications (Cambridge, England). PMID 29143030 DOI: 10.1039/c7cc04990k  0.8
2017 Kong W, Romo D. Diastereo- and Enantioselective Synthesis of Bi- and Tricyclic N-Heterocycle-Fused β-Lactones. The Journal of Organic Chemistry. PMID 29125760 DOI: 10.1021/acs.joc.7b02235  0.8
2017 Sidjui LS, Eyong KO, Hull KG, Folefoc GN, Leddet VM, Herbette G, Ollivier E, Taube J, Klausmeyer K, Romo D. Bioactive Seco-Lanostane-Type Triterpenoids from the Roots of Leplaea mayombensis. Journal of Natural Products. PMID 28945373 DOI: 10.1021/acs.jnatprod.7b00210  0.36
2017 Abbasov ME, Hudson BM, Tantillo DJ, Romo D. Stereodivergent, Diels-Alder-initiated organocascades employing α,β-unsaturated acylammonium salts: scope, mechanism, and application. Chemical Science. 8: 1511-1524. PMID 28616147 DOI: 10.1039/c6sc04273b  1
2017 McClary B, Zinshteyn B, Meyer M, Jouanneau M, Pellegrino S, Yusupova G, Schuller A, Reyes JCP, Lu J, Guo Z, Ayinde S, Luo C, Dang Y, Romo D, Yusupov M, et al. Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A. Cell Chemical Biology. PMID 28457705 DOI: 10.1016/j.chembiol.2017.04.006  1
2017 Abbasov ME, Hudson BM, Kong W, Tantillo DJ, Romo D. Enantioselective Diels-Alder-lactamization organocascades employing a furan-based diene. Organic & Biomolecular Chemistry. PMID 28358148 DOI: 10.1039/c6ob02738e  1
2017 Zhu M, Harshbarger WD, Robles O, Krysiak J, Hull KG, Cho SW, Richardson RD, Yang Y, Garcia A, Spiegelman L, Ramirez B, Wilson CT, Yau JA, Moore JT, Walker CB, ... ... Romo D, et al. A strategy for dual inhibition of the proteasome and fatty acid synthase with belactosin C-orlistat hybrids. Bioorganic & Medicinal Chemistry. PMID 28236510 DOI: 10.1016/j.bmc.2017.01.020  0.76
2016 Vellalath S, Romo D. Asymmetric Organocatalysis: The Emerging Utility of α,β-Unsaturated Acylammonium Salts. Angewandte Chemie (International Ed. in English). PMID 27650693 DOI: 10.1002/anie.201602217  0.56
2016 Finnen RL, Zhu M, Li J, Romo D, Banfield BW. HSV-2 Virion Host Shutoff Endoribonuclease Activity is Required to Disrupt Stress Granule Formation. Journal of Virology. PMID 27334584 DOI: 10.1128/JVI.00947-16  0.76
2016 Romo D, Liu JO. Editorial: Strategies for cellular target identification of natural products. Natural Product Reports. PMID 27118358 DOI: 10.1039/c6np90016j  1
2016 Jouanneau M, McClary B, Reyes JC, Chen R, Chen Y, Plunkett W, Cheng X, Milinichik AZ, Albone EF, Liu JO, Romo D. Derivatization of agelastatin A leading to bioactive analogs and a trifunctional probe. Bioorganic & Medicinal Chemistry Letters. PMID 26951751 DOI: 10.1016/j.bmcl.2016.02.051  1
2016 Bigley AN, Xiang DF, Ren Z, Xue H, Hull KG, Romo D, Raushel FM. Chemical Mechanism of the Phosphotriesterase from Sphingobium sp. Strain TCM1, an Enzyme Capable of Hydrolyzing Organophosphate Flame Retardants. Journal of the American Chemical Society. PMID 26907457 DOI: 10.1021/jacs.5b12739  0.6
2016 Yuan H, Houck KL, Tian Y, Bharadwaj U, Hull K, Zhou Z, Zhu M, Wu X, Tweardy DJ, Romo D, Fu X, Zhang Y, Zhang J, Dong JF. Correction: Piperlongumine Blocks JAK2-STAT3 to Inhibit Collagen-Induced Platelet Reactivity Independent of Reactive Oxygen Species†. Plos One. 11: e0146626. PMID 26727022 DOI: 10.1371/journal.pone.0146626  0.76
2015 Yuan H, Houck KL, Tian Y, Bharadwaj U, Hull K, Zhou Z, Zhou M, Wu X, Tweardy DJ, Romo D, Fu X, Zhang Y, Zhang J, Dong JF. Piperlongumine Blocks JAK2-STAT3 to Inhibit Collagen-Induced Platelet Reactivity Independent of Reactive Oxygen Species†. Plos One. 10: e0143964. PMID 26645674 DOI: 10.1371/journal.pone.0143964  0.6
2015 Xiang DF, Bigley AN, Ren Z, Xue H, Hull KG, Romo D, Raushel FM. Interrogation of the Substrate Profile and Catalytic Properties of the Phosphotriesterase from Sphingobium sp. Strain TCM1: An Enzyme Capable of Hydrolyzing Organophosphate Flame Retardants and Plasticizers. Biochemistry. PMID 26629649 DOI: 10.1021/acs.biochem.5b01144  1
2015 He QL, Titov DV, Li J, Tan M, Ye Z, Zhao Y, Romo D, Liu JO. Covalent modification of a cysteine residue in the XPB subunit of the general transcription factor TFIIH through single epoxide cleavage of the transcription inhibitor triptolide. Angewandte Chemie (International Ed. in English). 54: 1859-63. PMID 25504624 DOI: 10.1002/anie.201408817  1
2015 Harvey NL, Krysiak J, Chamni S, Cho SW, Sieber SA, Romo D. Synthesis of (±)-spongiolactone enabling discovery of a more potent derivative. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 1425-8. PMID 25488266 DOI: 10.1002/chem.201405980  1
2015 Vellalath S, Van KN, Romo D. Utility and NMR studies of α,β-unsaturated acylammonium salts: Synthesis of polycyclic dihydropyranones and a dihydropyridone Tetrahedron Letters. DOI: 10.1016/j.tetlet.2015.03.012  1
2014 Abbasov ME, Romo D. The ever-expanding role of asymmetric covalent organocatalysis in scalable, natural product synthesis. Natural Product Reports. 31: 1318-27. PMID 25042097 DOI: 10.1039/c4np00025k  1
2014 McMillan AW, Lopez MS, Zhu M, Morse BC, Yeo IC, Amos J, Hull K, Romo D, Glasner ME. Role of an active site loop in the promiscuous activities of Amycolatopsis sp. T-1-60 NSAR/OSBS. Biochemistry. 53: 4434-44. PMID 24955846 DOI: 10.1021/bi500573v  1
2014 Brizendine AM, Odokonyero D, McMillan AW, Zhu M, Hull K, Romo D, Glasner ME. Promiscuity of Exiguobacterium sp. AT1b o-succinylbenzoate synthase illustrates evolutionary transitions in the OSBS family. Biochemical and Biophysical Research Communications. 450: 679-84. PMID 24937446 DOI: 10.1016/j.bbrc.2014.06.034  1
2014 Abbasov ME, Hudson BM, Tantillo DJ, Romo D. Acylammonium salts as dienophiles in Diels-Alder/lactonization organocascades. Journal of the American Chemical Society. 136: 4492-5. PMID 24588428 DOI: 10.1021/ja501005g  1
2014 Robles O, Romo D. Chemo- and site-selective derivatizations of natural products enabling biological studies. Natural Product Reports. 31: 318-34. PMID 24468713 DOI: 10.1039/c3np70087a  1
2014 Low WK, Li J, Zhu M, Kommaraju SS, Shah-Mittal J, Hull K, Liu JO, Romo D. Second-generation derivatives of the eukaryotic translation initiation inhibitor pateamine A targeting eIF4A as potential anticancer agents. Bioorganic & Medicinal Chemistry. 22: 116-25. PMID 24359706 DOI: 10.1016/j.bmc.2013.11.046  1
2013 Liu G, Shirley ME, Van KN, McFarlin RL, Romo D. Rapid assembly of complex cyclopentanes employing chiral, α,β-unsaturated acylammonium intermediates. Nature Chemistry. 5: 1049-57. PMID 24256870 DOI: 10.1038/nchem.1788  1
2013 Vellalath S, Van KN, Romo D. Direct catalytic asymmetric synthesis of N-heterocycles from commodity acid chlorides by employing α,β-unsaturated acylammonium salts. Angewandte Chemie (International Ed. in English). 52: 13688-93. PMID 24173690 DOI: 10.1002/anie.201306050  1
2013 Zhou P, Zhang Y, Ma Q, Gu F, Day DS, He A, Zhou B, Li J, Stevens SM, Romo D, Pu WT. Interrogating translational efficiency and lineage-specific transcriptomes using ribosome affinity purification. Proceedings of the National Academy of Sciences of the United States of America. 110: 15395-400. PMID 24003143 DOI: 10.1073/pnas.1304124110  1
2013 Li J, Cisar JS, Zhou CY, Vera B, Williams H, Rodríguez AD, Cravatt BF, Romo D. Simultaneous structure-activity studies and arming of natural products by C-H amination reveal cellular targets of eupalmerin acetate. Nature Chemistry. 5: 510-7. PMID 23695633 DOI: 10.1038/nchem.1653  1
2013 Ranieri B, Robles O, Romo D. Concise synthesis of the isothiourea organocatalysts homobenzotetramisole and derivatives. The Journal of Organic Chemistry. 78: 6291-6. PMID 23688163 DOI: 10.1021/jo400603n  1
2012 Leverett CA, Purohit VC, Johnson AG, Davis RL, Tantillo DJ, Romo D. Dyotropic rearrangements of fused tricyclic β-lactones: application to the synthesis of (-)-curcumanolide A and (-)-curcumalactone. Journal of the American Chemical Society. 134: 13348-56. PMID 22853802 DOI: 10.1021/ja303414a  1
2012 Reyes JC, Romo D. Bioinspired total synthesis of agelastatin A. Angewandte Chemie (International Ed. in English). 51: 6870-3. PMID 22689447 DOI: 10.1002/anie.201200959  1
2012 Stout EP, Wang YG, Romo D, Molinski TF. Pyrrole aminoimidazole alkaloid metabiosynthesis with marine sponges Agelas conifera and Stylissa caribica. Angewandte Chemie (International Ed. in English). 51: 4877-81. PMID 22473581 DOI: 10.1002/anie.201108119  1
2012 Stout EP, Morinaka BI, Wang YG, Romo D, Molinski TF. De novo synthesis of benzosceptrin C and nagelamide H from 7-15N-oroidin: implications for pyrrole-aminoimidazole alkaloid biosynthesis. Journal of Natural Products. 75: 527-30. PMID 22455452 DOI: 10.1021/np300051k  1
2012 Robles O, Serna-Saldívar SO, Gutiérrez-Uribe JA, Romo D. Cyclopropanations of olefin-containing natural products for simultaneous arming and structure activity studies. Organic Letters. 14: 1394-7. PMID 22360738 DOI: 10.1021/ol300105q  1
2012 Liu G, Shirley ME, Romo D. A diastereoselective, nucleophile-promoted aldol-lactonization of ketoacids leading to bicyclic-β-lactones. The Journal of Organic Chemistry. 77: 2496-500. PMID 22260519 DOI: 10.1021/jo202252y  1
2012 Zhao C, Mitchell TA, Vallakati R, Pérez LM, Romo D. Mechanistic investigations of the ZnCl2-mediated tandem Mukaiyama aldol lactonization: evidence for asynchronous, concerted transition states and discovery of 2-oxopyridyl ketene acetal variants. Journal of the American Chemical Society. 134: 3084-94. PMID 22239064 DOI: 10.1021/ja209163w  1
2012 Nguyen H, Oh S, Henry-Riyad H, Sepulveda D, Romo D. Organocatalytic enantioselective synthesis of bicyclic β-lactones from aldehyde acids via nucleophile-catalyzed aldollactonization (NCAL) Organic Syntheses. 88: 121-137. DOI: 10.15227/orgsyn.088.0121  1
2011 Kong K, Moussa Z, Lee C, Romo D. Total synthesis of the spirocyclic imine marine toxin (-)-gymnodimine and an unnatural C4-epimer. Journal of the American Chemical Society. 133: 19844-56. PMID 22023219 DOI: 10.1021/ja207385y  1
2011 Chamni S, He QL, Dang Y, Bhat S, Liu JO, Romo D. Diazo reagents with small steric footprints for simultaneous arming/SAR studies of alcohol-containing natural products via O-H insertion. Acs Chemical Biology. 6: 1175-81. PMID 21894934 DOI: 10.1021/cb2002686  1
2011 Davis RL, Leverett CA, Romo D, Tantillo DJ. Switching between concerted and stepwise mechanisms for dyotropic rearrangements of β-lactones leading to spirocyclic, bridged γ-butyrolactones. The Journal of Organic Chemistry. 76: 7167-74. PMID 21770451 DOI: 10.1021/jo2012175  1
2011 Liu G, Romo D. Total synthesis of (+)-omphadiol. Angewandte Chemie (International Ed. in English). 50: 7537-40. PMID 21761524 DOI: 10.1002/anie.201102289  1
2011 Al-Mourabit A, Zancanella MA, Tilvi S, Romo D. Biosynthesis, asymmetric synthesis, and pharmacology, including cellular targets, of the pyrrole-2-aminoimidazole marine alkaloids. Natural Product Reports. 28: 1229-60. PMID 21556392 DOI: 10.1039/c0np00013b  1
2011 Agunanne E, Horvat D, Harrison R, Uddin MN, Jones R, Kuehl TJ, Ghanem DA, Berghman LR, Lai X, Li J, Romo D, Puschett JB. Marinobufagenin levels in preeclamptic patients: a preliminary report. American Journal of Perinatology. 28: 509-14. PMID 21380994 DOI: 10.1055/s-0031-1272965  1
2011 Abi-Ghanem D, Lai X, Berghman LR, Horvat D, Li J, Romo D, Uddin MN, Kamano Y, Nogawa T, Xu JP, Pettit GR, Puschett JB. A chemifluorescent immunoassay for the determination of marinobufagenin in body fluids. Journal of Immunoassay & Immunochemistry. 32: 31-46. PMID 21253968 DOI: 10.1080/15321819.2010.538107  1
2011 Bizzini A, Jaton K, Romo D, Bille J, Prod'hom G, Greub G. Matrix-assisted laser desorption ionization-time of flight mass spectrometry as an alternative to 16S rRNA gene sequencing for identification of difficult-to-identify bacterial strains. Journal of Clinical Microbiology. 49: 693-6. PMID 21106794 DOI: 10.1128/JCM.01463-10  1
2011 Nguyen H, Ma G, Gladysheva T, Fremgen T, Romo D. Bioinspired total synthesis and human proteasome inhibitory activity of (-)-salinosporamide A, (-)-homosalinosporamide A, and derivatives obtained via organonucleophile promoted bis-cyclizations. The Journal of Organic Chemistry. 76: 2-12. PMID 21047113 DOI: 10.1021/jo101638r  1
2010 Romo D. Natural-product synthesis: stitching together palau'amine. Nature Chemistry. 2: 159-60. PMID 21124468 DOI: 10.1038/nchem.565  1
2010 Leverett CA, Purohit VC, Romo D. Enantioselective, organocatalyzed, intramolecular aldol lactonizations with keto acids leading to bi- and tricyclic β-lactones and topology-morphing transformations. Angewandte Chemie (International Ed. in English). 49: 9479-83. PMID 21053228 DOI: 10.1002/anie.201004671  1
2010 Morris KA, Arendt KM, Oh SH, Romo D. Double diastereoselective, nucleophile-catalyzed aldol lactonizations (NCAL) leading to beta-lactone fused carbocycles and extensions to beta-lactone fused tetrahydrofurans. Organic Letters. 12: 3764-7. PMID 20704184 DOI: 10.1021/ol101388h  1
2010 Yau WL, Blisnick T, Taly JF, Helmer-Citterich M, Schiene-Fischer C, Leclercq O, Li J, Schmidt-Arras D, Morales MA, Notredame C, Romo D, Bastin P, Späth GF. Cyclosporin A treatment of Leishmania donovani reveals stage-specific functions of cyclophilins in parasite proliferation and viability. Plos Neglected Tropical Diseases. 4: e729. PMID 20614016 DOI: 10.1371/journal.pntd.0000729  1
2010 Nguyen H, Ma G, Romo D. A(1,3)-strain enabled retention of chirality during bis-cyclization of beta-ketoamides: total synthesis of (-)-salinosporamide A and (-)-homosalinosporamide A. Chemical Communications (Cambridge, England). 46: 4803-5. PMID 20498903 DOI: 10.1039/c0cc00607f  1
2010 Zhou CY, Li J, Peddibhotla S, Romo D. Mild arming and derivatization of natural products via an In(OTf)3-catalyzed arene iodination. Organic Letters. 12: 2104-7. PMID 20387852 DOI: 10.1021/ol100587j  1
2010 Wang YG, Morinaka BI, Reyes JC, Wolff JJ, Romo D, Molinski TF. Synthesis of 7-(15)N-Oroidin and evaluation of utility for biosynthetic studies of pyrrole-imidazole alkaloids by microscale (1)H-(15)N HSQC and FTMS. Journal of Natural Products. 73: 428-34. PMID 20095632 DOI: 10.1021/np900638e  1
2009 Duffy RJ, Morris KA, Romo D. Synthesis of Unusually Strained Spiro Ring Systems and Their Exploits in Synthesis. Tetrahedron. 65: 5879-5892. PMID 20640036 DOI: 10.1016/j.tet.2008.06.090  1
2009 Kong K, Romo D, Lee C. Enantioselective total synthesis of the marine toxin (-)-gymnodimine employing a Barbier-type macrocyclization. Angewandte Chemie (International Ed. in English). 48: 7402-5. PMID 19728353 DOI: 10.1002/anie.200903432  1
2009 Dang Y, Low WK, Xu J, Gehring NH, Dietz HC, Romo D, Liu JO. Inhibition of nonsense-mediated mRNA decay by the natural product pateamine A through eukaryotic initiation factor 4AIII. The Journal of Biological Chemistry. 284: 23613-21. PMID 19570977 DOI: 10.1074/jbc.M109.009985  1
2009 Duffy RJ, Morris KA, Vallakati R, Zhang W, Romo D. Asymmetric synthesis, structure, and reactivity of unexpectedly stable spiroepoxy-beta-lactones including facile conversion to tetronic acids: application to (+)-maculalactone A. The Journal of Organic Chemistry. 74: 4772-81. PMID 19453152 DOI: 10.1021/jo900499e  1
2009 Kuznetsov G, Xu Q, Rudolph-Owen L, Tendyke K, Liu J, Towle M, Zhao N, Marsh J, Agoulnik S, Twine N, Parent L, Chen Z, Shie JL, Jiang Y, Zhang H, ... ... Romo D, et al. Potent in vitro and in vivo anticancer activities of des-methyl, des-amino pateamine A, a synthetic analogue of marine natural product pateamine A. Molecular Cancer Therapeutics. 8: 1250-60. PMID 19417157 DOI: 10.1158/1535-7163.MCT-08-1026  1
2009 Liu G, Romo D. Enantioselective synthesis of schulzeines B and C via a beta-lactone-derived surrogate for bishomoserine aldehyde. Organic Letters. 11: 1143-6. PMID 19209875 DOI: 10.1021/ol802992m  1
2008 Mitchell TA, Zhao C, Romo D. Diastereoselective, three-component cascade synthesis of tetrahydrofurans and tetrahydropyrans employing the tandem Mukaiyama aldol-lactonization process. The Journal of Organic Chemistry. 73: 9544-51. PMID 19053579 DOI: 10.1021/jo801604k  1
2008 Richardson RD, Ma G, Oyola Y, Zancanella M, Knowles LM, Cieplak P, Romo D, Smith JW. Synthesis of novel beta-lactone inhibitors of fatty acid synthase. Journal of Medicinal Chemistry. 51: 5285-96. PMID 18710210 DOI: 10.1021/jm800321h  1
2008 Zancanella MA, Romo D. Facile synthesis of the trans-fused azabicyclo[3.3.0]octane core of the palau'amines and the tricyclic core of the axinellamines from a common intermediate. Organic Letters. 10: 3685-8. PMID 18693745 DOI: 10.1021/ol801289b  1
2008 Purohit VC, Matla AS, Romo D. Concise synthesis of spirocyclic, bridged gamma-butyrolactones via stereospecific, dyotropic rearrangements of beta-lactones involving 1,2-acyl and delta-lactone migrations. Journal of the American Chemical Society. 130: 10478-9. PMID 18627148 DOI: 10.1021/ja803579z  1
2008 Mitchell TA, Zhao C, Romo D. Highly diastereoselective, tandem, three-component synthesis of tetrahydrofurans from ketoaldehydes via silylated beta-lactone intermediates. Angewandte Chemie (International Ed. in English). 47: 5026-9. PMID 18504788 DOI: 10.1002/anie.200800235  1
2008 Zhang W, Richardson RD, Chamni S, Smith JW, Romo D. Beta-lactam congeners of orlistat as inhibitors of fatty acid synthase. Bioorganic & Medicinal Chemistry Letters. 18: 2491-4. PMID 18343106 DOI: 10.1016/j.bmcl.2008.02.043  1
2008 Wang S, Romo D. Enantioselective synthesis of (+)-monobromophakellin and (+)-phakellin: a concise phakellin annulation strategy applicable to Palau'amine. Angewandte Chemie (International Ed. in English). 47: 1284-6. PMID 18175299 DOI: 10.1002/anie.200703998  1
2008 Purohit VC, Matla AS, Romo D. Recent advances in Lewis base-catalyzed, stereoselective, tandem aldol β- and γ-lactonizations Heterocycles. 76: 949-979. DOI: 10.3987/REV-08-SR(N)7  1
2007 Mitchell TA, Romo D. Diastereoselective synthesis of tetrahydrofurans via mead reductive cyclization of keto-beta-lactones derived from the tandem Mukaiyama aldol lactonization (TMAL) process. The Journal of Organic Chemistry. 72: 9053-9. PMID 17973527 DOI: 10.1021/jo7014246  1
2007 Zhang W, Romo D. Transformation of fused bicyclic and tricyclic beta-lactones to fused gamma-lactones and 3(2H)-furanones via ring expansions and O-H insertions. The Journal of Organic Chemistry. 72: 8939-42. PMID 17929975 DOI: 10.1021/jo7012934  1
2007 Low WK, Dang Y, Schneider-Poetsch T, Shi Z, Choi NS, Rzasa RM, Shea HA, Li S, Park K, Ma G, Romo D, Liu JO. Isolation and identification of eukaryotic initiation factor 4A as a molecular target for the marine natural product Pateamine A. Methods in Enzymology. 431: 303-24. PMID 17923240 DOI: 10.1016/S0076-6879(07)31014-8  1
2007 Colucci G, Ferguson J, Harkleroad C, Lee S, Romo D, Soviero S, Thompson J, Velez M, Wang A, Miyahara Y, Young S, Sarrazin C. Improved COBAS TaqMan hepatitis C virus test (Version 2.0) for use with the High Pure system: enhanced genotype inclusivity and performance characteristics in a multisite study. Journal of Clinical Microbiology. 45: 3595-600. PMID 17898157 DOI: 10.1128/JCM.01320-07  0.48
2007 Peddibhotla S, Dang Y, Liu JO, Romo D. Simultaneous arming and structure/activity studies of natural products employing O-H insertions: an expedient and versatile strategy for natural products-based chemical genetics. Journal of the American Chemical Society. 129: 12222-31. PMID 17880073 DOI: 10.1021/ja0733686  1
2007 Low WK, Dang Y, Bhat S, Romo D, Liu JO. Substrate-dependent targeting of eukaryotic translation initiation factor 4A by pateamine A: negation of domain-linker regulation of activity. Chemistry & Biology. 14: 715-27. PMID 17584618 DOI: 10.1016/j.chembiol.2007.05.012  1
2007 Ma G, Nguyen H, Romo D. Concise total synthesis of (+/-)-salinosporamide A, (+/-)-cinnabaramide A, and derivatives via a bis-cyclization process: implications for a biosynthetic pathway? Organic Letters. 9: 2143-6. PMID 17477539 DOI: 10.1021/ol070616u  1
2007 Zhang W, Matla AS, Romo D. Alkyl C-O ring cleavage of bicyclic beta-lactones with Normant reagents: synthesis of a Merck IND intermediate. Organic Letters. 9: 2111-4. PMID 17477537 DOI: 10.1021/ol070572p  1
2007 Cho SW, Romo D. Total synthesis of (-)-belactosin C and derivatives via double diastereoselective tandem mukaiyama aldol lactonizations. Organic Letters. 9: 1537-40. PMID 17378572 DOI: 10.1021/ol070275k  1
2007 Tang L, Romo D. Synthesis of a cyclic guanidine hemiaminal pertinent to the axinellamines Heterocycles. 74: 999-1008.  1
2006 Zhou M, Sivaramakrishnan A, Ponnamperuma K, Low WK, Li C, Liu JO, Bergbreiter DE, Romo D. Synthesis, characterization, and utility of thermoresponsive natural/unnatural product macroligands for affinity chromatography. Organic Letters. 8: 5247-50. PMID 17078689 DOI: 10.1021/ol062045w  1
2006 Ma G, Zancanella M, Oyola Y, Richardson RD, Smith JW, Romo D. Total synthesis and comparative analysis of orlistat, valilactone, and a transposed orlistat derivative: Inhibitors of fatty acid synthase. Organic Letters. 8: 4497-500. PMID 16986934 DOI: 10.1021/ol061651o  1
2006 Henry-Riyad H, Lee C, Purohit VC, Romo D. Bicyclic- and tricyclic-beta-lactones via organonucleophile-promoted bis-cyclizations of keto acids: Enantioselective synthesis of (+)-dihydroplakevulin. Organic Letters. 8: 4363-6. PMID 16956227 DOI: 10.1002/CHIN.200703091  1
2006 Dang Y, Kedersha N, Low WK, Romo D, Gorospe M, Kaufman R, Anderson P, Liu JO. Eukaryotic initiation factor 2alpha-independent pathway of stress granule induction by the natural product pateamine A. The Journal of Biological Chemistry. 281: 32870-8. PMID 16951406 DOI: 10.1074/jbc.M606149200  1
2006 Kong K, Romo D. Diastereoselective, vinylogous mukaiyama aldol additions of silyloxy furans to cyclic ketones: annulation of butenolides and gamma-lactones. Organic Letters. 8: 2909-12. PMID 16805514 DOI: 10.1021/ol060534q  1
2006 Purohit VC, Richardson RD, Smith JW, Romo D. Practical, catalytic, asymmetric synthesis of beta-lactones via a sequential ketene dimerization/hydrogenation process: inhibitors of the thioesterase domain of fatty acid synthase. The Journal of Organic Chemistry. 71: 4549-58. PMID 16749788 DOI: 10.1021/jo060392d  1
2006 Moussa Z, Romo D. Mild deprotection of primary N-(p-toluenesulfonyl) amides with SmI 2 following trifluoroacetylation Synlett. 3294-3298. DOI: 10.1055/s-2006-951530  1
2006 Wang S, Dilley AS, Poullennec KG, Romo D. Planned and unplanned halogenations in route to selected oroidin alkaloids Tetrahedron. 62: 7155-7161. DOI: 10.1016/j.tet.2006.01.115  1
2006 Dransfield PJ, Dilley AS, Wang S, Romo D. A unified synthetic strategy toward oroidin-derived alkaloids premised on a biosynthetic proposal Tetrahedron. 62: 5223-5247. DOI: 10.1016/j.tet.2005.12.068  1
2005 Low WK, Dang Y, Schneider-Poetsch T, Shi Z, Choi NS, Merrick WC, Romo D, Liu JO. Inhibition of eukaryotic translation initiation by the marine natural product pateamine A. Molecular Cell. 20: 709-22. PMID 16337595 DOI: 10.1016/j.molcel.2005.10.008  1
2005 Duffy RJ, Morris KA, Romo D. Synthesis, structure, and reactivity of unexpectedly stable spiroepoxy-beta-lactones obtained by epoxidation of 4-alkylidene-2-oxetanones. Journal of the American Chemical Society. 127: 16754-5. PMID 16316199 DOI: 10.1021/ja053478h  1
2005 Kong K, Moussa Z, Romo D. Studies toward a marine toxin immunogen: enantioselective synthesis of the spirocyclic imine of (-)-gymnodimine. Organic Letters. 7: 5127-30. PMID 16268519 DOI: 10.1021/ol051840r  1
2005 Dransfield PJ, Wang S, Dilley A, Romo D. Highly regioselective Diels-Alder reactions toward oroidin alkaloids: use of a tosylvinyl moiety as a nitrogen masking group with adjustable electronics. Organic Letters. 7: 1679-82. PMID 15844879 DOI: 10.1021/ol0473602  1
2005 Oh SH, Cortez GS, Romo D. Asymmetric synthesis of bicyclic beta-lactones via the intramolecular, nucleophile-catalyzed aldol lactonization: improved efficiency and expanded scope. The Journal of Organic Chemistry. 70: 2835-8. PMID 15787582 DOI: 10.1021/jo050024u  1
2005 Andrew Mitchell T, Romo D. Radical reactions and α-silylations of optically active 4-trichloromethyl-β-lactone Heterocycles. 66: 627-637. DOI: 10.3987/COM-05-S(K)53  1
2004 Romo D, Choi NS, Li S, Buchler I, Shi Z, Liu JO. Evidence for separate binding and scaffolding domains in the immunosuppressive and antitumor marine natural product, pateamine a: design, synthesis, and activity studies leading to a potent simplified derivative. Journal of the American Chemical Society. 126: 10582-8. PMID 15327314 DOI: 10.1021/ja040065s  1
2004 Wang Y, Tennyson RL, Romo D. β-lactones: Intermediates for natural product total synthesis and new transformations Heterocycles. 64: 605-658. DOI: 10.3987/REV-04-SR(P)3  1
2003 Poullennec KG, Romo D. Enantioselective total synthesis of (+)-dibromophakellstatin. Journal of the American Chemical Society. 125: 6344-5. PMID 12785755 DOI: 10.1021/ja034575i  1
2002 Singleton DA, Wang Y, Yang HW, Romo D. Mechanism and origin of stereoselectivity in Lewis acid catalyzed [2 + 2] cycloadditions of ketenes with aldehydes. Angewandte Chemie (International Ed. in English). 41: 1572-5. PMID 19750669  1
2002 Wang Y, Romo D. Concise total synthesis of (+)-brefeldin A: a combined beta-lactone/cross-metathesis-based strategy. Organic Letters. 4: 3231-4. PMID 12227756 DOI: 10.1021/ol026438g  1
2002 Poullennec KG, Kelly AT, Romo D. Highly diastereoselective desymmetrizations of cyclo(Pro,Pro): an enantioselective strategy toward phakellstatin and phakellin. Organic Letters. 4: 2645-8. PMID 12153199 DOI: 10.1021/ol026140q  1
2002 Tennyson RL, Cortez GS, Galicia HJ, Kreiman CR, Thompson CM, Romo D. A beta-lactone route to chiral gamma-substituted alpha-amino acids: application to the concise synthesis of (S)-alpha-azidobutyro lactone and a natural amino acid. Organic Letters. 4: 533-6. PMID 11843584 DOI: 10.1021/ol017120b  1
2002 Yokota Y, Cortez GS, Romo D. Nucleophilic openings of bicyclic β-lactones via acyl C-O and alkyl C-O cleavage: Catalytic, asymmetric synthesis of a versatile, carbocyclic nucleoside precursor and protected transpentacin Tetrahedron. 58: 7075-7080. DOI: 10.1016/S0040-4020(02)00703-2  1
2002 Singleton DA, Wang Y, Yang HW, Romo D. Mechanism and origin of stereoselectivity in Lewis acid catalyzed [2 + 2] cycloadditions of ketenes with aldehydes Angewandte Chemie - International Edition. 41: 1572-1575. DOI: 10.1002/1521-3773(20020503)41:9<1572::AID-ANIE1572>3.0.CO;2-B  1
2001 Cortez GS, Tennyson RL, Romo D. Intramolecular, nucleophile-catalyzed aldol-lactonization (NCAL) reactions: catalytic, asymmetric synthesis of bicyclic beta-lactones. Journal of the American Chemical Society. 123: 7945-6. PMID 11493084 DOI: 10.1021/ja016134+  1
2001 Dilley AS, Romo D. Enantioselective strategy to the spirocyclic core of Palau'amine and related bisguanidine marine alkaloids. Organic Letters. 3: 1535-8. PMID 11388860 DOI: 10.1021/ol015864j  1
2001 Ahn Y, Cardenas GI, Yang J, Romo D. Studies toward gymnodimine: development of a single-pot Hua reaction for the synthesis of highly hindered cyclic imines. Organic Letters. 3: 751-4. PMID 11259053 DOI: 10.1021/ol0155081  1
2001 Cortez GS, Oh SH, Romo D. Bicyclic β-lactones via intramolecular NCAL reactions with cinchona alkaloids: Effect of the C9-substituent on enantioselectivity and catalyst conformation Synthesis. 1731-1736.  1
2000 Romo D, Rzasa RM, Schmitz WD, Yang J, Cohn ST, Buchler IP, Shea HA, Park K, Langenhan JM, Messerschmidt NB, Cox MM. Total synthesis of marine natural products driven by novel structure, potent biological activity, and/or synthetic methodology. Ernst Schering Research Foundation Workshop. 103-48. PMID 11077607  1
2000 Yang J, Cohn ST, Romo D. Studies toward (-)-gymnodimine: concise routes to the spirocyclic and tetrahydrofuran moieties. Organic Letters. 2: 763-6. PMID 10754678  1
2000 Tennyson R, Romo D. Use of in situ generated ketene in the wynberg β-lactone synthesis: New transformations of the dichlorinated β-lactone products Journal of Organic Chemistry. 65: 7248-7252. DOI: 10.1021/jo001010l  1
1999 Yang HW, Romo D. A single-pot, mild conversion of β-lactones to β-lactams Journal of Organic Chemistry. 64: 7657-7660. DOI: 10.1021/jo990826n  1
1999 Yang HW, Romo D. Methods for the synthesis of optically active β-lactones (2- oxetanones) Tetrahedron. 55: 6403-6434. DOI: 10.1016/S0040-4020(99)00185-4  1
1999 Wang Y, Zhao C, Romo D. A stereocomplementary approach to β-lactones: Highly diastereoselective synthesis of cis-β-lactones, a β-chloro acid, and a tetrahydrofuran Organic Letters. 1: 1197-1199.  1
1998 Romo D, Harrison PH, Jenkins SI, Riddoch RW, Park K, Yang HW, Zhao C, Wright GD. Synthesis and inhibitory action on HMG-CoA synthase of racemic and optically active oxetan-2-ones (beta-lactones). Bioorganic & Medicinal Chemistry. 6: 1255-72. PMID 9784867 DOI: 10.1016/S0968-0896(98)00114-X  1
1998 Romo D, Rzasa RM, Shea HA, Park K, Langenhan JM, Sun L, Akhiezer A, Liu JO. Total synthesis and immunosuppressive activity of (-)-pateamine A and related compounds: Implementation of a β-lactam-based macrocyclization Journal of the American Chemical Society. 120: 12237-12254. DOI: 10.1021/ja981846u  1
1998 Rzasa RM, Shea HA, Romo D. Total synthesis of the novel, immunosuppressive agent (-)-pateamine A from Mycale sp. employing a β-lactam-based macrocyclization Journal of the American Chemical Society. 120: 591-592. DOI: 10.1021/ja973549f  1
1998 Yang HW, Romo D. Studies of the asymmetric [2+2] cycloaddition of silylketenes and aldehydes employing Ti-TADDOL catalysts Tetrahedron Letters. 39: 2877-2880. DOI: 10.1016/S0040-4039(98)00422-5  1
1997 Yang HW, Romo D. A Highly Diastereoselective, Tandem Mukaiyama Aldol-Lactonization Route to beta-Lactones: Application to a Concise Synthesis of the Potent Pancreatic Lipase Inhibitor, (-)-Panclicin D. The Journal of Organic Chemistry. 62: 4-5. PMID 11671357  1
1997 Yang HW, Romo D. A highly diastereoselective, tandem Mukaiyama aldol-lactonization route to β-lactones: Application to a concise synthesis of the potent pancreatic lipase inhibitor, (-)-panclicin D Journal of Organic Chemistry. 62: 4-5. DOI: 10.1021/jo9619488  1
1997 Yang HW, Zhao C, Romo D. Studies of the tandem mukaiyama aldol-lactonization (TMAL) reaction: A concise and highly diastereoselective route to β-lactones applied to the total synthesis of the potent pancreatic lipase inhibitor, (-)-Panclicin D Tetrahedron. 53: 16471-16488. DOI: 10.1016/S0040-4020(97)01029-6  1
1995 Rzasa RM, Romo D, Stirling DJ, Blunt JW, Munro MHG. Structural and synthetic studies of the pateamines: Synthesis and absolute configuration of the hydroxydienoate fragment Tetrahedron Letters. 36: 5307-5310. DOI: 10.1016/0040-4039(95)01021-9  1
1991 Romo D, Meyers AI. Chiral non-racemic bicyclic lactams. Vehicles for the construction of natural and unnatural products containing quaternary carbon centers Tetrahedron. 47: 9503-9569. DOI: 10.1016/S0040-4020(01)91024-5  1
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