Prabhat Arya - Publications

Affiliations: 
1985 CSIR-National Chemical Laboratory, Pune, India 
 1989-2009 National Research Council of Canada, Canada 
 1994-2009 University of Ottawa, Ottawa, ON, Canada 
 2009-2018 Dr. Reddy’s Institute of Life Sciences, University of Hyderabad 
Area:
Biochemistry, bioorganic chemistry, chemical biology
Website:
http://www.prabhatarya.org/index.html

37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Guduru SKR, Arya P. Synthesis and biological evaluation of rapamycin-derived, next generation small molecules. Medchemcomm. 9: 27-43. PMID 30108899 DOI: 10.1039/c7md00474e  0.52
2017 Jogula S, Soorneedi AR, Gaddam J, Chamakuri S, Deora GS, Indarapu RK, Ramgopal MK, Dravida S, Arya P. Geldanamycin-inspired compounds induce direct trans-differentiation of human mesenchymal stem cells to neurons. European Journal of Medicinal Chemistry. 135: 110-116. PMID 28441579 DOI: 10.1016/j.ejmech.2017.03.082  1
2017 Niu X, Brahmbhatt H, Mergenthaler P, Zhang Z, Sang J, Daude M, Ehlert FG, Diederich WE, Wong E, Zhu W, Pogmore J, Nandy JP, Satyanarayana M, Jimmidi RK, Arya P, et al. A Small-Molecule Inhibitor of Bax and Bak Oligomerization Prevents Genotoxic Cell Death and Promotes Neuroprotection. Cell Chemical Biology. PMID 28392146 DOI: 10.1016/j.chembiol.2017.03.011  1
2015 Chamakuri S, Jogula S, Arya P. Regio- and Stereocontrolled Dieckmann Approach to Treprostinil-Inspired, Polycyclic Scaffold For Building Macrocyclic Diversity. Acs Combinatorial Science. 17: 437-41. PMID 26167941 DOI: 10.1021/acscombsci.5b00076  1
2015 Guduru SK, Jimmidi R, Deora GS, Arya P. Stereoselective synthesis of rapamycin fragment to build a macrocyclic toolbox. Organic Letters. 17: 480-3. PMID 25583255 DOI: 10.1021/ol5034833  1
2015 Aeluri M, Dasari B, Arya P. Divergent approach to building a latrunculin family derived hybrid macrocyclic toolbox. Organic Letters. 17: 472-5. PMID 25583127 DOI: 10.1021/ol503465p  1
2015 Jimmidi R, Guduru SK, Arya P. Practical stereoselective synthesis of eribulin fragment toward building a hybrid macrocyclic toolbox. Organic Letters. 17: 468-71. PMID 25583003 DOI: 10.1021/ol503464s  1
2015 Dasari B, Jimmidi R, Arya P. Selected hybrid natural products as tubulin modulators. European Journal of Medicinal Chemistry. 94: 497-508. PMID 25455639 DOI: 10.1016/j.ejmech.2014.10.062  1
2014 Aeluri M, Chamakuri S, Dasari B, Guduru SK, Jimmidi R, Jogula S, Arya P. Small molecule modulators of protein-protein interactions: selected case studies. Chemical Reviews. 114: 4640-94. PMID 24673632 DOI: 10.1021/cr4004049  1
2013 Reddy Guduru SK, Chamakuri S, Chandrasekar G, Kitambi SS, Arya P. Tetrahydroquinoline-derived macrocyclic toolbox: the discovery of antiangiogenesis agents in zebrafish assay. Acs Medicinal Chemistry Letters. 4: 666-70. PMID 24900727 DOI: 10.1021/ml400026n  1
2013 Aeluri M, Pramanik C, Chetia L, Mallurwar NK, Balasubramanian S, Chandrasekar G, Kitambi SS, Arya P. 14-Membered macrocyclic ring-derived toolbox: the identification of small molecule inhibitors of angiogenesis and early embryo development in zebrafish assay. Organic Letters. 15: 436-9. PMID 23331174 DOI: 10.1021/ol3032126  1
2013 Dasari B, Jogula S, Borhade R, Balasubramanian S, Chandrasekar G, Kitambi SS, Arya P. Macrocyclic glycohybrid toolbox identifies novel antiangiogenesis agents from zebrafish assay. Organic Letters. 15: 432-5. PMID 23331160 DOI: 10.1021/ol3032297  1
2009 Mokas S, Mills JR, Garreau C, Fournier MJ, Robert F, Arya P, Kaufman RJ, Pelletier J, Mazroui R. Uncoupling stress granule assembly and translation initiation inhibition. Molecular Biology of the Cell. 20: 2673-83. PMID 19369421 DOI: 10.1091/mbc.E08-10-1061  1
2009 Nandy JP, Prakesch M, Khadem S, Reddy PT, Sharma U, Arya P. Advances in solution- and solid-phase synthesis toward the generation of natural product-like libraries. Chemical Reviews. 109: 1999-2060. PMID 19249849 DOI: 10.1021/cr800188v  1
2009 Poondra RR, Kumar NN, Bijian K, Prakesch M, Campagna-Slater V, Reayi A, Reddy PT, Choudhry A, Barnes ML, Leek DM, Daroszewska M, Lougheed C, Xu B, Schapira M, Alaoui-Jamali MA, ... Arya P, et al. Discovery of indoline-based, natural-product-like compounds as probes of focal adhesion kinase signaling pathways. Journal of Combinatorial Chemistry. 11: 303-9. PMID 19146410 DOI: 10.1021/cc8001525  1
2008 Prakesch M, Bijian K, Campagna-Slater V, Quevillon S, Joseph R, Wei CQ, Sesmilo E, Reayi A, Poondra RR, Barnes ML, Leek DM, Xu B, Lougheed C, Schapira M, Alaoui-Jamali M, ... Arya P, et al. Building skeletally diverse architectures on the Indoline Scaffold: the discovery of a chemical probe of focal adhesion kinase signaling networks. Bioorganic & Medicinal Chemistry. 16: 9596-602. PMID 18835181 DOI: 10.1016/j.bmc.2008.09.025  1
2008 Prakesch M, Denisov AY, Naim M, Gehring K, Arya P. The discovery of small molecule chemical probes of Bcl-X(L) and Mcl-1. Bioorganic & Medicinal Chemistry. 16: 7443-9. PMID 18603434 DOI: 10.1016/j.bmc.2008.06.023  1
2008 Brochu JL, Prakesch M, Enright GD, Leek DM, Arya P. Reagent-based, modular, tandem Michael approach for obtaining different indoline alkaloid-inspired polycyclic architectures. Journal of Combinatorial Chemistry. 10: 405-20. PMID 18419163 DOI: 10.1021/cc800036w  1
2008 Nandy JP, Rakic B, Sarma BV, Babu N, Lefrance M, Enright GD, Leek DM, Daniel K, Sabourin LA, Arya P. Benzofuran-derived cyclic beta-amino acid scaffold for building a diverse set of flavonoid-like probes and the discovery of a cell motility inhibitor. Organic Letters. 10: 1143-6. PMID 18302395 DOI: 10.1021/ol800050g  1
2006 Reddy PT, Quevillon S, Gan Z, Forbes N, Leek DM, Arya P. Solution- and solid-phase, modular approaches for obtaining different natural product-like polycyclic architectures from an aminoindoline scaffold for combinatorial chemistry. Journal of Combinatorial Chemistry. 8: 856-71. PMID 17096575 DOI: 10.1021/cc0600573  1
2006 Prakesch M, Srivastava S, Leek DM, Arya P. Part 3. a novel stereocontrolled, in situ, solution- and solid-phase, Aza Michael approach for high-throughput generation of tetrahydroaminoquinoline-derived natural-product-like architectures. Journal of Combinatorial Chemistry. 8: 762-73. PMID 16961412 DOI: 10.1021/cc060059n  1
2006 Sharma U, Srivastava S, Prakesch M, Sharma M, Leek DM, Arya P. Part 2: building diverse natural-product-like architectures from a tetrahydroaminoquinoline scaffold. Modular solution- and solid-phase approaches for use in high-throughput generation of chemical probes. Journal of Combinatorial Chemistry. 8: 735-61. PMID 16961411 DOI: 10.1021/cc060056a  1
2006 Prakesch M, Sharma U, Sharma M, Khadem S, Leek DM, Arya P. Part 1. modular approach to obtaining diverse tetrahydroquinoline-derived polycyclic skeletons for use in high-throughput generation of natural-product-like chemical probes. Journal of Combinatorial Chemistry. 8: 715-34. PMID 16961410 DOI: 10.1021/cc060055i  1
2005 Reayi A, Arya P. Natural product-like chemical space: Search for chemical dissectors of macromolecular interactions Current Opinion in Chemical Biology. 9: 240-247. PMID 15939325 DOI: 10.1016/j.cbpa.2005.04.007  1
2005 Arya P, Joseph R, Gan Z, Rakic B. Exploring new chemical space by stereocontrolled diversity-oriented synthesis. Chemistry & Biology. 12: 163-80. PMID 15734644 DOI: 10.1016/j.chembiol.2005.01.011  1
2005 Gan Z, Reddy PT, Quevillon S, Couve-Bonnaire S, Arya P. Stereocontrolled solid-phase synthesis of a 90-membered library of indoline-alkaloid-like polycycles from an enantioenriched aminoindoline scaffold. Angewandte Chemie (International Ed. in English). 44: 1366-8. PMID 15674986 DOI: 10.1002/anie.200462298  1
2004 Arya P, Couve-Bonnaire S, Durieux P, Laforce D, Kumar R, Leek DM. Solution- and solid-phase synthesis of natural product-like tetrahydroquinoline-based polycyclics having a medium size ring. Journal of Combinatorial Chemistry. 6: 735-45. PMID 15360208 DOI: 10.1021/cc049935s  1
2004 Khadem S, Joseph R, Rastegar M, Leek DM, Oudatchin KA, Arya P. A solution- and solid-phase approach to tetrahydroquinoline-derived polycyclics having a 10-membered ring. Journal of Combinatorial Chemistry. 6: 724-34. PMID 15360207 DOI: 10.1021/cc049941o  1
2004 Couve-Bonnaire S, Chou DT, Gan Z, Arya P. A solid-phase, library synthesis of natural-product-like derivatives from an enantiomerically pure tetrahydroquinoline scaffold. Journal of Combinatorial Chemistry. 6: 73-7. PMID 14714987 DOI: 10.1021/cc030026x  1
2004 Arya P, Wei CQ, Barnes ML, Daroszewska M. A solid phase library synthesis of hydroxyindoline-derived tricyclic derivatives by Mitsunobu approach. Journal of Combinatorial Chemistry. 6: 65-72. PMID 14714986 DOI: 10.1021/cc0340067  1
2004 Arya P, Durieux P, Chen ZX, Joseph R, Leek DM. Stereoselective diversity-oriented solution and solid-phase synthesis of tetrahydroquinoline-based polycyclic derivatives. Journal of Combinatorial Chemistry. 6: 54-64. PMID 14714985 DOI: 10.1021/cc034053z  1
2002 Antebi S, Arya P, Manzer LE, Alper H. Carbonylation reactions of iodoarenes with PAMAM dendrimer-palladium catalysts immobilized on silica. The Journal of Organic Chemistry. 67: 6623-31. PMID 12227790 DOI: 10.1021/jo020271n  1
2002 Arya P, Barkley A, Randell KD. Automated high-throughput synthesis of artificial glycopeptides. Small-molecule probes for chemical glycobiology. Journal of Combinatorial Chemistry. 4: 193-8. PMID 12005477  1
2002 Randell KD, Barkley A, Arya P. High-throughput chemistry toward complex carbohydrates and carbohydrate-like compounds. Combinatorial Chemistry & High Throughput Screening. 5: 179-93. PMID 11966426  1
2002 Arya P, Joseph R, Chou DT. Toward high-throughput synthesis of complex natural product-like compounds in the genomics and proteomics age. Chemistry & Biology. 9: 145-56. PMID 11880029  1
2001 Arya P, Chou DTH, Baek MG. Diversity-Based Organic Synthesis in the Era of Genomics and Proteomics. Angewandte Chemie (International Ed. in English). 40: 339-346. PMID 29712387 DOI: 10.1002/1521-3773(20010119)40:2<339::AID-ANIE339>3.0.CO;2-J  1
2001 Arya P, Chou DT, Baek MG. Diversity-Based Organic Synthesis in the Era of Genomics and Proteomics NRC publication no. 43843. David Thomas is a senior colleague and mentor. Angewandte Chemie (International Ed. in English). 40: 339-346. PMID 11180320 DOI: 10.1002/1521-3773(20010119)40:2<339::AID-ANIE339>3.0.CO;2-J  1
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