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D. Eric Walters - Publications

Affiliations: 
1991- Pharmacy Rosalind Franklin University of Medicine and Science, North Chicago, IL, United States 
Area:
computer modeling of proteins and computer aided drug design
Website:
https://www.rosalindfranklin.edu/academics/faculty/eric-walters/

60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ghosh AK, Williams JN, Kovela S, Takayama J, Simpson HM, Walters DE, Hattori SI, Aoki M, Mitsuya H. Potent HIV-1 protease inhibitors incorporating squaramide-derived P2 ligands: Design, synthesis, and biological evaluation. Bioorganic & Medicinal Chemistry Letters. PMID 31416666 DOI: 10.1016/J.Bmcl.2019.08.006  1
2015 Babkin P, George Thompson AM, Iancu CV, Walters DE, Choe JY. Antipsychotics inhibit glucose transport: Determination of olanzapine binding site in Staphylococcus epidermidis glucose/H(+) symporter. Febs Open Bio. 5: 335-40. PMID 25941630 DOI: 10.1016/J.Fob.2015.04.006  1
2014 Ghosh AK, Schiltz GE, Rusere LN, Osswald HL, Walters DE, Amano M, Mitsuya H. Design and synthesis of potent macrocyclic HIV-1 protease inhibitors involving P1-P2 ligands. Organic & Biomolecular Chemistry. 12: 6842-54. PMID 25050776 DOI: 10.1039/C4Ob00738G  1
2013 Tong JJ, Sohn BC, Lam A, Walters DE, Vertel BM, Ebihara L. Properties of two cataract-associated mutations located in the NH2 terminus of connexin 46. American Journal of Physiology. Cell Physiology. 304: C823-32. PMID 23302783 DOI: 10.1152/Ajpcell.00344.2012  1
2013 Walters DE. Team-based learning applied to a medicinal chemistry course. Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre. 22: 2-3. PMID 23006824 DOI: 10.1159/000342819  0.01
2012 Symersky J, Osowski D, Walters DE, Mueller DM. Oligomycin frames a common drug-binding site in the ATP synthase. Proceedings of the National Academy of Sciences of the United States of America. 109: 13961-5. PMID 22869738 DOI: 10.1073/Pnas.1207912109  1
2011 Ghosh AK, Chapsal BD, Baldridge A, Steffey MP, Walters DE, Koh Y, Amano M, Mitsuya H. Design and synthesis of potent HIV-1 protease inhibitors incorporating hexahydrofuropyranol-derived high affinity P(2) ligands: structure-activity studies and biological evaluation. Journal of Medicinal Chemistry. 54: 622-34. PMID 21194227 DOI: 10.1021/Jm1012787  1
2010 López Cascales JJ, Oliveira Costa SD, de Groot BL, Walters DE. Binding of glutamate to the umami receptor. Biophysical Chemistry. 152: 139-44. PMID 20961679 DOI: 10.1016/J.Bpc.2010.09.001  0.01
2010 Sun J, Aluvila S, Kotaria R, Mayor JA, Walters DE, Kaplan RS. Mitochondrial and Plasma Membrane Citrate Transporters: Discovery of Selective Inhibitors and Application to Structure/Function Analysis. Molecular and Cellular Pharmacology. 2: 101-110. PMID 20686672 DOI: 10.4255/mcpharmacol.10.14  1
2010 Oh KJ, Singh P, Lee K, Foss K, Lee S, Park M, Lee S, Aluvila S, Park M, Singh P, Kim RS, Symersky J, Walters DE. Conformational changes in BAK, a pore-forming proapoptotic Bcl-2 family member, upon membrane insertion and direct evidence for the existence of BH3-BH3 contact interface in BAK homo-oligomers. The Journal of Biological Chemistry. 285: 28924-37. PMID 20605789 DOI: 10.1074/Jbc.M110.135293  1
2010 Aluvila S, Kotaria R, Sun J, Mayor JA, Walters DE, Harrison DH, Kaplan RS. The yeast mitochondrial citrate transport protein: molecular determinants of its substrate specificity. The Journal of Biological Chemistry. 285: 27314-26. PMID 20551333 DOI: 10.1074/Jbc.M110.137364  1
2010 Sackin H, Nanazashvili M, Li H, Palmer LG, Walters DE. A conserved arginine near the filter of Kir1.1 controls Rb/K selectivity. Channels (Austin, Tex.). 4: 203-14. PMID 20458182 DOI: 10.4161/Chan.4.3.11982  1
2010 Mayor JA, Sun J, Kotaria R, Walters DE, Oh KJ, Kaplan RS. Probing the effect of transport inhibitors on the conformation of the mitochondrial citrate transport protein via a site-directed spin labeling approach. Journal of Bioenergetics and Biomembranes. 42: 99-109. PMID 20354774 DOI: 10.1007/S10863-010-9280-0  1
2010 Egwolf B, Luo Y, Walters DE, Roux B. Ion selectivity of alpha-hemolysin with beta-cyclodextrin adapter. II. Multi-ion effects studied with grand canonical Monte Carlo/Brownian dynamics simulations. The Journal of Physical Chemistry. B. 114: 2901-9. PMID 20146515 DOI: 10.1021/Jp906791B  1
2010 Luo Y, Egwolf B, Walters DE, Roux B. Ion selectivity of alpha-hemolysin with a beta-cyclodextrin adapter. I. Single ion potential of mean force and diffusion coefficient. The Journal of Physical Chemistry. B. 114: 952-8. PMID 20041673 DOI: 10.1021/Jp906790F  1
2010 Ghosh AK, Gemma S, Simoni E, Baldridge A, Walters DE, Ide K, Tojo Y, Koh Y, Amano M, Mitsuya H. Synthesis and biological evaluation of novel allophenylnorstatine-based HIV-1 protease inhibitors incorporating high affinity P2-ligands. Bioorganic & Medicinal Chemistry Letters. 20: 1241-6. PMID 20034787 DOI: 10.1016/J.Bmcl.2009.11.123  1
2010 Aluvila S, Sun J, Harrison DH, Walters DE, Kaplan RS. Inhibitors of the mitochondrial citrate transport protein: validation of the role of substrate binding residues and discovery of the first purely competitive inhibitor. Molecular Pharmacology. 77: 26-34. PMID 19843634 DOI: 10.1124/Mol.109.058750  1
2009 Walters DE, Cragin T, Jin Z, Rumbley JN, Hellekant G. Design and evaluation of new analogs of the sweet protein brazzein. Chemical Senses. 34: 679-83. PMID 19696120 DOI: 10.1093/Chemse/Bjp048  1
2009 Sackin H, Nanazashvili M, Li H, Palmer LG, Walters DE. An intersubunit salt bridge near the selectivity filter stabilizes the active state of Kir1.1. Biophysical Journal. 97: 1058-66. PMID 19686653 DOI: 10.1016/J.Bpj.2009.05.056  1
2009 Harder E, Walters DE, Bodnar YD, Faibish RS, Roux B. Molecular dynamics study of a polymeric reverse osmosis membrane. The Journal of Physical Chemistry. B. 113: 10177-82. PMID 19586002 DOI: 10.1021/Jp902715F  1
2008 Remani S, Sun J, Kotaria R, Mayor JA, Brownlee JM, Harrison DH, Walters DE, Kaplan RS. The yeast mitochondrial citrate transport protein: identification of the Lysine residues responsible for inhibition mediated by Pyridoxal 5'-phosphate. Journal of Bioenergetics and Biomembranes. 40: 577-85. PMID 19002576 DOI: 10.1007/S10863-008-9187-1  1
2008 Shen H, Walters DE, Mueller DM. Introduction of the chloroplast redox regulatory region in the yeast ATP synthase impairs cytochrome c oxidase. The Journal of Biological Chemistry. 283: 32937-43. PMID 18819926 DOI: 10.1074/Jbc.M805310200  1
2007 Nanazashvili M, Li H, Palmer LG, Walters DE, Sackin H. Moving the pH gate of the Kir1.1 inward rectifier channel. Channels (Austin, Tex.). 1: 21-8. PMID 19170254 DOI: 10.4161/Chan.3707  1
2007 Sackin H, Nanazashvili M, Li H, Palmer LG, Walters DE. External K activation of Kir1.1 depends on the pH gate. Biophysical Journal. 93: L14-6. PMID 17496015 DOI: 10.1529/Biophysj.107.110122  1
2007 Ma C, Remani S, Sun J, Kotaria R, Mayor JA, Walters DE, Kaplan RS. Identification of the substrate binding sites within the yeast mitochondrial citrate transport protein. The Journal of Biological Chemistry. 282: 17210-20. PMID 17400551 DOI: 10.1074/Jbc.M611268200  1
2007 Hartman WR, Walters DE, Hentosh P. Presence of the anti-leukemic nucleotide analog, 2-chloro-2'-deoxyadenosine-5'-monophosphate, in a promoter sequence alters DNA binding of TATA-binding protein (TBP). Archives of Biochemistry and Biophysics. 459: 223-32. PMID 17320040 DOI: 10.1016/J.Abb.2006.12.031  1
2006 Walters DE, Hellekant G. Interactions of the sweet protein brazzein with the sweet taste receptor. Journal of Agricultural and Food Chemistry. 54: 10129-33. PMID 17177550 DOI: 10.1021/Jf062359Y  1
2006 Ghosh AK, Sridhar PR, Leshchenko S, Hussain AK, Li J, Kovalevsky AY, Walters DE, Wedekind JE, Grum-Tokars V, Das D, Koh Y, Maeda K, Gatanaga H, Weber IT, Mitsuya H. Structure-based design of novel HIV-1 protease inhibitors to combat drug resistance. Journal of Medicinal Chemistry. 49: 5252-61. PMID 16913714 DOI: 10.1021/Jm060561M  1
2006 Ma C, Remani S, Kotaria R, Mayor JA, Walters DE, Kaplan RS. The mitochondrial citrate transport protein: evidence for a steric interaction between glutamine 182 and leucine 120 and its relationship to the substrate translocation pathway and identification of other mechanistically essential residues. Biochimica Et Biophysica Acta. 1757: 1271-6. PMID 16904062 DOI: 10.1016/J.Bbabio.2006.06.011  1
2006 Ghosh AK, Schiltz G, Perali RS, Leshchenko S, Kay S, Walters DE, Koh Y, Maeda K, Mitsuya H. Design and synthesis of novel HIV-1 protease inhibitors incorporating oxyindoles as the P2'-ligands. Bioorganic & Medicinal Chemistry Letters. 16: 1869-73. PMID 16480871 DOI: 10.1016/J.Bmcl.2006.01.011  1
2005 Ghosh AK, Swanson LM, Cho H, Leshchenko S, Hussain KA, Kay S, Walters DE, Koh Y, Mitsuya H. Structure-based design: synthesis and biological evaluation of a series of novel cycloamide-derived HIV-1 protease inhibitors. Journal of Medicinal Chemistry. 48: 3576-85. PMID 15887965 DOI: 10.1021/Jm050019I  1
2005 Sackin H, Nanazashvili M, Palmer LG, Krambis M, Walters DE. Structural locus of the pH gate in the Kir1.1 inward rectifier channel. Biophysical Journal. 88: 2597-606. PMID 15653740 DOI: 10.1529/Biophysj.104.051474  1
2005 Ma C, Kotaria R, Mayor JA, Remani S, Walters DE, Kaplan RS. The yeast mitochondrial citrate transport protein: characterization of transmembrane domain III residue involvement in substrate translocation. The Journal of Biological Chemistry. 280: 2331-40. PMID 15498760 DOI: 10.1074/Jbc.M411474200  1
2004 Walters DE, Kaplan RS. Homology-modeled structure of the yeast mitochondrial citrate transport protein. Biophysical Journal. 87: 907-11. PMID 15298898 DOI: 10.1529/Biophysj.104.042127  1
2004 Foley TT, Hentosh P, Walters DE. 2-Chloro-2'-deoxyadenosine: alteration of DNA:TATA element binding protein (TBP) interactions. Journal of Molecular Modeling. 10: 32-7. PMID 14610662 DOI: 10.1007/S00894-003-0163-8  1
2004 Ma C, Kotaria R, Mayor JA, Eriks LR, Dean AM, Walters DE, Kaplan RS. The mitochondrial citrate transport protein: probing the secondary structure of transmembrane domain III, identification of residues that likely comprise a portion of the citrate transport pathway, and development of a model for the putative TMDIII-TMDIII' interface. The Journal of Biological Chemistry. 279: 1533-40. PMID 14561747 DOI: 10.1074/Jbc.M310866200  1
2002 Ghosh AK, Swanson LM, Liu C, Hussain KA, Cho H, Walters DE, Holland L, Buthod J. Novel cyclourethane-derived HIV protease inhibitors: a ring-closing olefin metathesis based strategy. Bioorganic & Medicinal Chemistry Letters. 12: 1993-6. PMID 12113826 DOI: 10.1016/S0960-894X(02)00300-1  1
2001 Ghosh AK, Shin D, Swanson L, Krishnan K, Cho H, Hussain KA, Walters DE, Holland L, Buthod J. Structure-based design of non-peptide HIV protease inhibitors. Farmaco (Società Chimica Italiana : 1989). 56: 29-32. PMID 11347961 DOI: 10.1016/S0014-827X(01)01025-4  1
2001 Prakash I, Bishay IE, Desai N, Walters DE. Modifying the temporal profile of the high-potency sweetener neotame. Journal of Agricultural and Food Chemistry. 49: 786-9. PMID 11262029  1
2001 Sackin H, Syn S, Palmer LG, Choe H, Walters DE. Regulation of ROMK by extracellular cations. Biophysical Journal. 80: 683-97. PMID 11159436 DOI: 10.1016/S0006-3495(01)76048-1  1
2000 Walters DE. Predictive models of protein-active sites. Methods in Molecular Biology (Clifton, N.J.). 143: 349-58. PMID 11084913 DOI: 10.1385/1-59259-368-2:349  0.01
2000 Kaplan RS, Mayor JA, Kotaria R, Walters DE, McHaourab HS. The yeast mitochondrial citrate transport protein: determination of secondary structure and solvent accessibility of transmembrane domain IV using site-directed spin labeling. Biochemistry. 39: 9157-63. PMID 10924109 DOI: 10.1021/Bi000433E  1
2000 Kaplan RS, Mayor JA, Brauer D, Kotaria R, Walters DE, Dean AM. The yeast mitochondrial citrate transport protein. Probing the secondary structure of transmembrane domain iv and identification of residues that likely comprise a portion of the citrate translocation pathway. The Journal of Biological Chemistry. 275: 12009-16. PMID 10766832 DOI: 10.1074/Jbc.275.16.12009  1
2000 Walters DE, Prakash I, Desai N. Active conformations of neotame and other high-potency sweeteners. Journal of Medicinal Chemistry. 43: 1242-5. PMID 10737757  1
2000 Xu Y, Kakhniashvili DA, Gremse DA, Wood DO, Mayor JA, Walters DE, Kaplan RS. The yeast mitochondrial citrate transport protein. Probing the roles of cysteines, Arg(181), and Arg(189) in transporter function. The Journal of Biological Chemistry. 275: 7117-24. PMID 10702279 DOI: 10.1074/Jbc.275.10.7117  1
1999 Kotaria R, Mayor JA, Walters DE, Kaplan RS. Oligomeric state of wild-type and cysteine-less yeast mitochondrial citrate transport proteins. Journal of Bioenergetics and Biomembranes. 31: 543-9. PMID 10682912 DOI: 10.1023/A:1005460810527  1
1998 Ghosh AK, Kincaid JF, Cho W, Walters DE, Krishnan K, Hussain KA, Koo Y, Cho H, Rudall C, Holland L, Buthod J. Potent HIV protease inhibitors incorporating high-affinity P2-ligands and (R)-(hydroxyethylamino)sulfonamide isostere. Bioorganic & Medicinal Chemistry Letters. 8: 687-90. PMID 9871583 DOI: 10.1016/S0960-894X(98)00098-5  1
1998 Ghosh AK, Krishnan K, Walters DE, Cho W, Cho H, Koo Y, Trevino J, Holland L, Buthod J. Structure based design: novel spirocyclic ethers as nonpeptidal P2-ligands for HIV protease inhibitors. Bioorganic & Medicinal Chemistry Letters. 8: 979-82. PMID 9871524 DOI: 10.1016/S0960-894X(98)00139-5  1
1998 Hinds RM, Xu J, Walters DE, Kemp RG. The active site of pyrophosphate-dependent phosphofructo-1-kinase based on site-directed mutagenesis and molecular modeling. Archives of Biochemistry and Biophysics. 349: 47-52. PMID 9439581 DOI: 10.1006/abbi.1997.0434  1
1996 Ghosh AK, Kincaid JF, Walters DE, Chen Y, Chaudhuri NC, Thompson WJ, Culberson C, Fitzgerald PM, Lee HY, McKee SP, Munson PM, Duong TT, Darke PL, Zugay JA, Schleif WA, et al. Nonpeptidal P2 ligands for HIV protease inhibitors: structure-based design, synthesis, and biological evaluation. Journal of Medicinal Chemistry. 39: 3278-90. PMID 8765511 DOI: 10.1021/Jm960128K  1
1994 Walters DE, Hinds RM. Genetically evolved receptor models: a computational approach to construction of receptor models. Journal of Medicinal Chemistry. 37: 2527-36. PMID 8057298  1
1992 Muller GW, Culberson JC, Roy G, Ziegler J, Walters DE, Kellogg MS, Schiffman SS, Warwick ZS. Carboxylic acid replacement structure-activity relationships in suosan type sweeteners. A sweet taste antagonist. 1. Journal of Medicinal Chemistry. 35: 1747-51. PMID 1588556  1
1992 Muller GW, Walters DE, DuBois GE. N,N'-disubstituted guanidine high-potency sweeteners. Journal of Medicinal Chemistry. 35: 740-3. PMID 1542101  1
1991 Lane BG, Bernier F, Dratewka-Kos E, Shafai R, Kennedy TD, Pyne C, Munro JR, Vaughan T, Walters D, Altomare F. Homologies between members of the germin gene family in hexaploid wheat and similarities between these wheat germins and certain Physarum Spherulins Journal of Biological Chemistry. 266: 10461-10469. PMID 2037593  1
1991 Carrington M, Walters D, Webb H. The biology of the glycosylphosphatidylinositol-specific phospholipase C of Trypanosoma brucei Cell Biology International Reports. 15: 1101-1114. PMID 1838304 DOI: 10.1016/0309-1651(91)90058-Q  1
1988 Pitzele BS, Moormann AE, Gullikson GW, Albin D, Bianchi RG, Palicharla P, Sanguinetti EL, Walters DE. Potential antisecretory antidiarrheals. 1. Alpha 2-adrenergic aromatic aminoguanidine hydrazones. Journal of Medicinal Chemistry. 31: 138-44. PMID 2891854  1
1981 Berman E, Walters DE, Allerhand A. Structure and dynamic behavior of the oligosaccharide side chain of bovine pancreatic ribonuclease B. Application of carbon 13 nuclear magnetic resonance spectroscopy. The Journal of Biological Chemistry. 256: 3853-7. PMID 7217059  1
1980 Walters DE, Allerhand A. Tautomeric states of the histidine residues of bovine pancreatic ribonuclease A. Application of carbon 13 nuclear magnetic resonance spectroscopy. The Journal of Biological Chemistry. 255: 6200-4. PMID 7391017  1
1979 Grunewald GL, Creese MW, Walters DE. APPLICATION OF CNDO/2 CALCULATIONS AND X-RAY CRYSTALLOGRAPHIC ANALYSIS OF THE DESIGN OF CONFORMATIONALLY DEFINED ANALOGS OF METHAMPHETAMINE Acs Symposium Series. 439-487.  1
1978 Grunewald GL, Walters DE, Kroboth TR. Synthesis of bridgehead hydroxyl-substituted benzobicyclo[3.2.1]octenes and -octadienes via an acyloin rearrangement in the benzobicyclo[2.2.2]octene ring system Journal of Organic Chemistry. 43: 3478-3481. DOI: 10.1021/Jo00412A012  1
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