| Year |
Citation |
Score |
| 2023 |
Quilbe A, Mustapha R, Duchêne B, Kumar A, Werkmeister E, Leteurtre E, Moralès O, Jonckheere N, Van Seuningen I, Delhem N. A novel anti-galectin-9 immunotherapy limits the early progression of pancreatic neoplastic lesions in transgenic mice. Frontiers in Immunology. 14: 1267279. PMID 38098486 DOI: 10.3389/fimmu.2023.1267279 |
0.657 |
|
| 2023 |
Jannin A, Dessein AF, Do Cao C, Vantyghem MC, Chevalier B, Van Seuningen I, Jonckheere N, Coppin L. Metabolism of pancreatic neuroendocrine tumors: what can omics tell us? Frontiers in Endocrinology. 14: 1248575. PMID 37908747 DOI: 10.3389/fendo.2023.1248575 |
0.631 |
|
| 2022 |
Auwercx J, Kischel P, Lefebvre T, Jonckheere N, Vanlaeys A, Guénin S, Radoslavova S, Van Seuningen I, Ouadid-Ahidouch H, Kocher HM, Dhennin-Duthille I, Gautier M. TRPM7 Modulates Human Pancreatic Stellate Cell Activation. Cells. 11. PMID 35883700 DOI: 10.3390/cells11142255 |
0.728 |
|
| 2021 |
Boukrout N, Souidi M, Lahdaoui F, Duchêne B, Neve B, Coppin L, Leteurtre E, Torrisani J, Van Seuningen I, Jonckheere N. Antagonistic Roles of the Tumor Suppressor miR-210-3p and Oncomucin MUC4 Forming a Negative Feedback Loop in Pancreatic Adenocarcinoma. Cancers. 13. PMID 34944818 DOI: 10.3390/cancers13246197 |
0.812 |
|
| 2021 |
Stoup N, Liberelle M, Schulz C, Cavdarli S, Vasseur R, Magnez R, Lahdaoui F, Skrypek N, Peretti F, Frénois F, Thuru X, Melnyk P, Renault N, Jonckheere N, Lebègue N, ... Van Seuningen I, et al. The EGF Domains of MUC4 Oncomucin Mediate HER2 Binding Affinity and Promote Pancreatic Cancer Cell Tumorigenesis. Cancers. 13. PMID 34830899 DOI: 10.3390/cancers13225746 |
0.797 |
|
| 2021 |
Hadj Bachir E, Poiraud C, Paget S, Stoup N, El Moghrabi S, Duchêne B, Jouy N, Bongiovanni A, Tardivel M, Weiswald LB, Vandepeutte M, Beugniez C, Escande F, Leteurtre E, ... ... Van Seuningen I, et al. A new pancreatic adenocarcinoma-derived organoid model of acquired chemoresistance to FOLFIRINOX: First insight of the underlying mechanisms. Biology of the Cell. PMID 34561874 DOI: 10.1111/boc.202100003 |
0.77 |
|
| 2021 |
Wavelet-Vermuse C, Groux-Degroote S, Vicogne D, Cogez V, Venturi G, Trinchera M, Brysbaert G, Krzewinski-Recchi MA, Bachir EH, Schulz C, Vincent A, Van Seuningen I, Harduin-Lepers A. BBA gene regulation mechanisms research paper analysis of the proximal promoter of the human colon-specific B4GALNT2 (Sd synthase) gene: B4GALNT2 is transcriptionally regulated by ETS1. Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms. 194747. PMID 34500083 DOI: 10.1016/j.bbagrm.2021.194747 |
0.688 |
|
| 2021 |
Jonckheere N, Vincent A, Neve B, Van Seuningen I. Mucin expression, epigenetic regulation and patient survival: A toolkit of prognostic biomarkers in epithelial cancers. Biochimica Et Biophysica Acta. Reviews On Cancer. 188538. PMID 33862149 DOI: 10.1016/j.bbcan.2021.188538 |
0.819 |
|
| 2021 |
Bauzone M, Souidi M, Dessein AF, Wisztorski M, Vincent A, Gimeno JP, Monte D, Van Seuningen I, Gespach C, Huet G. Crosstalk between YAP and RAR-RXR drives expression of stemness genes to promote 5-FU resistance and self-renewal in colorectal cancer cells. Molecular Cancer Research : McR. PMID 33472949 DOI: 10.1158/1541-7786.MCR-20-0462 |
0.701 |
|
| 2021 |
Auwercx J, Rybarczyk P, Kischel P, Dhennin-Duthille I, Chatelain D, Sevestre H, Van Seuningen I, Ouadid-Ahidouch H, Jonckheere N, Gautier M. Mg Transporters in Digestive Cancers. Nutrients. 13. PMID 33450887 DOI: 10.3390/nu13010210 |
0.671 |
|
| 2020 |
Jonckheere N, Auwercx J, Hadj Bachir E, Coppin L, Boukrout N, Vincent A, Neve B, Gautier M, Treviño V, Van Seuningen I. Unsupervised Hierarchical Clustering of Pancreatic Adenocarcinoma Dataset from TCGA Defines a Mucin Expression Profile that Impacts Overall Survival. Cancers. 12. PMID 33182511 DOI: 10.3390/cancers12113309 |
0.772 |
|
| 2020 |
Neve B, Jonckheere N, Vincent A, Van Seuningen I. Long non-coding RNAs: the tentacles of chromatin remodeler complexes. Cellular and Molecular Life Sciences : Cmls. PMID 33001247 DOI: 10.1007/s00018-020-03646-0 |
0.746 |
|
| 2020 |
Roberti MP, Yonekura S, Duong CPM, Picard M, Ferrere G, Tidjani Alou M, Rauber C, Iebba V, Lehmann CHK, Amon L, Dudziak D, Derosa L, Routy B, Flament C, Richard C, ... ... Van Seuningen I, et al. Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer. Nature Medicine. PMID 32451498 DOI: 10.1038/S41591-020-0882-8 |
0.66 |
|
| 2020 |
Coppin L, Jannin A, Ait Yahya E, Thuillier C, Villenet C, Tardivel M, Bongiovanni A, Gaston C, de Beco S, Barois N, van Seuningen I, Durand E, Bonnefond A, Vienne JC, Vamecq J, et al. Galectin-3 modulates epithelial cell adaptation to stress at the ER-mitochondria interface. Cell Death & Disease. 11: 360. PMID 32398681 DOI: 10.1038/S41419-020-2556-3 |
0.635 |
|
| 2020 |
Liberelle M, Jonckheere N, Melnyk P, Van Seuningen I, Lebègue N. EGF-Containing Membrane-Bound Mucins: A Hidden ErbB2 Targeting Pathway? Journal of Medicinal Chemistry. PMID 32027502 DOI: 10.1021/Acs.Jmedchem.9B02001 |
0.667 |
|
| 2019 |
Vincent A, Ouelkdite-Oumouchal A, Souidi M, Leclerc J, Neve B, Van Seuningen I. Colon cancer stemness as a reversible epigenetic state: Implications for anticancer therapies. World Journal of Stem Cells. 11: 920-936. PMID 31768220 DOI: 10.4252/Wjsc.V11.I11.920 |
0.703 |
|
| 2019 |
El Amrani M, Corfiotti F, Corvaisier M, Vasseur R, Fulbert M, Skrzypczyk C, Deshorgues AC, Gnemmi V, Tulasne D, Lahdaoui F, Vincent A, Pruvot FR, Van Seuningen I, Huet G, Truant S. Gemcitabine-induced epithelial-mesenchymal transition-like changes sustain chemoresistance of pancreatic cancer cells of mesenchymal-like phenotype. Molecular Carcinogenesis. PMID 31373074 DOI: 10.1002/mc.23090 |
0.826 |
|
| 2019 |
Jonckheere N, Van Seuningen I. Fine-tuning autophagy in pancreatic adenocarcinoma: full blockage is required. Annals of Translational Medicine. 7: S43. PMID 31032322 DOI: 10.21037/Atm.2019.03.01 |
0.696 |
|
| 2018 |
Neve B, Jonckheere N, Vincent A, Van Seuningen I. Epigenetic Regulation by lncRNAs: An Overview Focused on UCA1 in Colorectal Cancer. Cancers. 10. PMID 30441811 DOI: 10.3390/Cancers10110440 |
0.821 |
|
| 2018 |
Jonckheere N, Van Seuningen I. Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas. Journal of Translational Medicine. 16: 259. PMID 30236127 DOI: 10.1186/S12967-018-1632-2 |
0.682 |
|
| 2018 |
Drubay V, Skrypek N, Cordiez L, Vasseur R, Schulz C, Boukrout N, Duchêne B, Coppin L, Van Seuningen I, Jonckheere N. TGF-βRII Knock-down in Pancreatic Cancer Cells Promotes Tumor Growth and Gemcitabine Resistance. Importance of STAT3 Phosphorylation on S727. Cancers. 10. PMID 30065235 DOI: 10.3390/Cancers10080254 |
0.817 |
|
| 2017 |
Lahdaoui F, Messager M, Vincent A, Hec F, Gandon A, Warlaumont M, Renaud F, Leteurtre E, Piessen G, Jonckheere N, Mariette C, Van Seuningen I. Depletion of MUC5B mucin in gastrointestinal cancer cells alters their tumorigenic properties: Implication of the Wnt/β-catenin pathway. The Biochemical Journal. PMID 28972071 DOI: 10.1042/Bcj20170348 |
0.833 |
|
| 2017 |
Jonckheere N, Vasseur R, Van Seuningen I. The cornerstone K-RAS mutation in pancreatic adenocarcinoma: From cell signaling network, target genes, biological processes to therapeutic targeting. Critical Reviews in Oncology/Hematology. 111: 7-19. PMID 28259298 DOI: 10.1016/J.Critrevonc.2017.01.002 |
0.641 |
|
| 2017 |
Porte R, Van Maele L, Muñoz-Wolf N, Foligné B, Dumoutier L, Tabareau J, Cayet D, Gosset P, Jonckheere N, Van Seuningen I, Chabalgoity JA, Simonet M, Lamkanfi M, Renauld JC, Sirard JC, et al. Flagellin-Mediated Protection against Intestinal Yersinia pseudotuberculosis Infection Does Not Require Interleukin-22. Infection and Immunity. 85. PMID 27872237 DOI: 10.1128/Iai.00806-16 |
0.614 |
|
| 2016 |
Corvaisier M, Bauzone M, Corfiotti F, Renaud F, El Amrani M, Monté D, Truant S, Leteurtre E, Formstecher P, Van Seuningen I, Gespach C, Huet G. Regulation of cellular quiescence by YAP/TAZ and Cyclin E1 in colon cancer cells: Implication in chemoresistance and cancer relapse. Oncotarget. PMID 27527859 DOI: 10.18632/oncotarget.11057 |
0.343 |
|
| 2016 |
De Arcangelis A, Hamade H, Alpy F, Normand S, Bruyère E, Lefebvre O, Méchine-Neuville A, Siebert S, Pfister V, Lepage P, Laquerriere P, Dembele D, Delanoye-Crespin A, Rodius S, Robine S, ... ... Van Seuningen I, et al. Hemidesmosome integrity protects the colon against colitis and colorectal cancer. Gut. PMID 27371534 DOI: 10.1136/Gutjnl-2015-310847 |
0.807 |
|
| 2015 |
Jonckheere N, Lahdaoui F, Van Seuningen I. Targeting MUC4 in pancreatic cancer: miRNAs. Oncoscience. 2: 799-800. PMID 26682251 DOI: 10.18632/oncoscience.249 |
0.785 |
|
| 2015 |
Vasseur R, Skrypek N, Duchêne B, Renaud F, Martínez-Maqueda D, Vincent A, Porchet N, Van Seuningen I, Jonckheere N. The mucin MUC4 is a transcriptional and post-transcriptional target of K-ras oncogene in pancreatic cancer. Implication of MAPK/AP-1, NF-κB and RalB signaling pathways. Biochimica Et Biophysica Acta. 1849: 1375-1384. PMID 26477488 DOI: 10.1016/J.Bbagrm.2015.10.014 |
0.803 |
|
| 2015 |
Renaud F, Mariette C, Vincent A, Wacrenier A, Maunoury V, Leclerc J, Coppin L, Crépin M, Van Seuningen I, Leteurtre E, Buisine MP. The serrated neoplasia pathway of colorectal tumors: Identification of MUC5AC hypomethylation as an early marker of polyps with malignant potential. International Journal of Cancer. Journal International Du Cancer. PMID 26476272 DOI: 10.1002/Ijc.29891 |
0.659 |
|
| 2015 |
Tréhoux S, Lahdaoui F, Delpu Y, Renaud F, Leteurtre E, Torrisani J, Jonckheere N, Van Seuningen I. Micro-RNAs miR-29a and miR-330-5p function as tumor suppressors by targeting the MUC1 mucin in pancreatic cancer cells. Biochimica Et Biophysica Acta. 1853: 2392-403. PMID 26036346 DOI: 10.1016/J.Bbamcr.2015.05.033 |
0.762 |
|
| 2015 |
Skrypek N, Vasseur R, Vincent A, Duchêne B, Van Seuningen I, Jonckheere N. The oncogenic receptor ErbB2 modulates gemcitabine and irinotecan/SN-38 chemoresistance of human pancreatic cancer cells via hCNT1 transporter and multidrug-resistance associated protein MRP-2. Oncotarget. 6: 10853-67. PMID 25890497 DOI: 10.18632/Oncotarget.3414 |
0.816 |
|
| 2015 |
Vincent A, Kazmierczak C, Duchêne B, Jonckheere N, Leteurtre E, Van Seuningen I. Cryosectioning the intestinal crypt-villus axis: an ex vivo method to study the dynamics of epigenetic modifications from stem cells to differentiated cells. Stem Cell Research. 14: 105-13. PMID 25590428 DOI: 10.1016/J.Scr.2014.12.002 |
0.774 |
|
| 2015 |
Desurmont T, Skrypek N, Duhamel A, Jonckheere N, Millet G, Leteurtre E, Gosset P, Duchene B, Ramdane N, Hebbar M, Van Seuningen I, Pruvot FR, Huet G, Truant S. Overexpression of chemokine receptor CXCR2 and ligand CXCL7 in liver metastases from colon cancer is correlated to shorter disease-free and overall survival. Cancer Science. 106: 262-9. PMID 25580640 DOI: 10.1111/Cas.12603 |
0.804 |
|
| 2015 |
Tréhoux S, Duchêne B, Jonckheere N, Van Seuningen I. The MUC1 oncomucin regulates pancreatic cancer cell biological properties and chemoresistance. Implication of p42-44 MAPK, Akt, Bcl-2 and MMP13 pathways. Biochemical and Biophysical Research Communications. 456: 757-62. PMID 25511698 DOI: 10.1016/J.Bbrc.2014.12.025 |
0.817 |
|
| 2015 |
Renaud F, Vincent A, Mariette C, Crépin M, Stechly L, Truant S, Copin MC, Porchet N, Leteurtre E, Van Seuningen I, Buisine MP. MUC5AC hypomethylation is a predictor of microsatellite instability independently of clinical factors associated with colorectal cancer. International Journal of Cancer. Journal International Du Cancer. 136: 2811-21. PMID 25403854 DOI: 10.1002/Ijc.29342 |
0.683 |
|
| 2015 |
Gronnier C, Piessen G, Leteurtre E, Van Seuningen I, Mariette C. Suitability of surgically induced chronic reflux in rats for studying esophageal carcinogenesis. Annals of Surgery. 261: e140-1. PMID 24374550 DOI: 10.1097/Sla.0000000000000474 |
0.429 |
|
| 2014 |
Tréton X, Pedruzzi E, Guichard C, Ladeiro Y, Sedghi S, Vallée M, Fernandez N, Bruyère E, Woerther PL, Ducroc R, Montcuquet N, Freund JN, Van Seuningen I, Barreau F, Marah A, et al. Combined NADPH oxidase 1 and interleukin 10 deficiency induces chronic endoplasmic reticulum stress and causes ulcerative colitis-like disease in mice. Plos One. 9: e101669. PMID 25014110 DOI: 10.1371/Journal.Pone.0101669 |
0.776 |
|
| 2014 |
Gronnier C, Bruyère E, Lahdaoui F, Jonckheere N, Perrais M, Leteurtre E, Piessen G, Mariette C, Van Seuningen I. The MUC1 mucin regulates the tumorigenic properties of human esophageal adenocarcinomatous cells. Biochimica Et Biophysica Acta. 1843: 2432-7. PMID 25003315 DOI: 10.1016/J.Bbamcr.2014.06.021 |
0.814 |
|
| 2014 |
Jonckheere N, Vincent A, Van Seuningen I. Of autophagy and in vivo pancreatic carcinogenesis: the p53 status matters! Clinics and Research in Hepatology and Gastroenterology. 38: 423-5. PMID 24939064 DOI: 10.1016/J.Clinre.2014.04.009 |
0.792 |
|
| 2014 |
Vincent A, Hong SM, Hu C, Omura N, Young A, Kim H, Yu J, Knight S, Ayars M, Griffith M, Van Seuningen I, Maitra A, Goggins M. Epigenetic silencing of EYA2 in pancreatic adenocarcinomas promotes tumor growth. Oncotarget. 5: 2575-87. PMID 24810906 DOI: 10.18632/Oncotarget.1842 |
0.749 |
|
| 2014 |
Jonckheere N, Skrypek N, Van Seuningen I. Mucins and tumor resistance to chemotherapeutic drugs. Biochimica Et Biophysica Acta. 1846: 142-51. PMID 24785432 DOI: 10.1016/J.Bbcan.2014.04.008 |
0.823 |
|
| 2014 |
Bouillez A, Gnemmi V, Gaudelot K, Hémon B, Ringot B, Pottier N, Glowacki F, Butruille C, Cauffiez C, Hamdane M, Sergeant N, Van Seuningen I, Leroy X, Aubert S, Perrais M. MUC1-C nuclear localization drives invasiveness of renal cancer cells through a sheddase/gamma secretase dependent pathway. Oncotarget. 5: 754-63. PMID 24504508 DOI: 10.18632/Oncotarget.1768 |
0.342 |
|
| 2014 |
Touil Y, Igoudjil W, Corvaisier M, Dessein AF, Vandomme J, Monte D, Stechly L, Skrypek N, Langlois C, Grard G, Millet G, Leteurtre E, Dumont P, Truant S, Pruvot FR, ... ... Van Seuningen I, et al. Colon cancer cells escape 5FU chemotherapy-induced cell death by entering stemness and quiescence associated with the c-Yes/YAP axis Clinical Cancer Research. 20: 837-846. PMID 24323901 DOI: 10.1158/1078-0432.Ccr-13-1854 |
0.78 |
|
| 2014 |
Jonckheere N, Van Seuningen I. Comment on: Functional MUC4 suppress epithelial-mesenchymal transition in lung adenocarcinoma metastasis. Gao L, Liu J, Zhang B, Zhang H, Wang D, Zhang T, Liu Y, Wang C. Tumour Biol. 2013, in press. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 35: 3941-2. PMID 24241961 DOI: 10.1007/S13277-013-1390-Y |
0.654 |
|
| 2014 |
Perrais M, Rousseaux C, Ducourouble MP, Courcol R, Vincent P, Jonckheere N, Van Seuningen I. Helicobacter pylori urease and flagellin alter mucin gene expression in human gastric cancer cells. Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association. 17: 235-46. PMID 23703470 DOI: 10.1007/S10120-013-0267-5 |
0.668 |
|
| 2013 |
Gronnier C, Bruyère E, Piessen G, Briez N, Bot J, Buob D, Leteurtre E, Van Seuningen I, Mariette C. Operatively induced chronic reflux in rats: a suitable model for studying esophageal carcinogenesis? Surgery. 154: 955-67. PMID 24084597 DOI: 10.1016/J.Surg.2013.05.029 |
0.758 |
|
| 2013 |
Bobowski M, Vincent A, Steenackers A, Colomb F, Van Seuningen I, Julien S, Delannoy P. Estradiol represses the G(D3) synthase gene ST8SIA1 expression in human breast cancer cells by preventing NFκB binding to ST8SIA1 promoter. Plos One. 8: e62559. PMID 23626833 DOI: 10.1371/Journal.Pone.0062559 |
0.691 |
|
| 2013 |
Jonckheere N, Skrypek N, Frénois F, Van Seuningen I. Membrane-bound mucin modular domains: from structure to function. Biochimie. 95: 1077-86. PMID 23178705 DOI: 10.1016/J.Biochi.2012.11.005 |
0.765 |
|
| 2012 |
Jonckheere N, Vincent A, Franquet-Ansart H, Witte-Bouma J, Korteland-van Male A, Leteurtre E, Renes IB, Van Seuningen I. GATA-4/-6 and HNF-1/-4 families of transcription factors control the transcriptional regulation of the murine Muc5ac mucin during stomach development and in epithelial cancer cells. Biochimica Et Biophysica Acta. 1819: 869-76. PMID 22554936 DOI: 10.1016/J.Bbagrm.2012.04.003 |
0.797 |
|
| 2012 |
Streppel MM, Vincent A, Mukherjee R, Campbell NR, Chen SH, Konstantopoulos K, Goggins MG, Van Seuningen I, Maitra A, Montgomery EA. Mucin 16 (cancer antigen 125) expression in human tissues and cell lines and correlation with clinical outcome in adenocarcinomas of the pancreas, esophagus, stomach, and colon. Human Pathology. 43: 1755-63. PMID 22542127 DOI: 10.1016/J.Humpath.2012.01.005 |
0.706 |
|
| 2012 |
Vincent A, Van Seuningen I. On the epigenetic origin of cancer stem cells. Biochimica Et Biophysica Acta. 1826: 83-8. PMID 22495062 DOI: 10.1016/J.Bbcan.2012.03.009 |
0.703 |
|
| 2012 |
Vincent DF, Gout J, Chuvin N, Arfi V, Pommier RM, Bertolino P, Jonckheere N, Ripoche D, Kaniewski B, Martel S, Langlois JB, Goddard-Léon S, Colombe A, Janier M, Van Seuningen I, et al. Tif1γ suppresses murine pancreatic tumoral transformation by a Smad4-independent pathway. The American Journal of Pathology. 180: 2214-21. PMID 22469842 DOI: 10.1016/J.Ajpath.2012.02.006 |
0.689 |
|
| 2012 |
Jonckheere N, Skrypek N, Merlin J, Dessein AF, Dumont P, Leteurtre E, Harris A, Desseyn JL, Susini C, Frénois F, Van Seuningen I. The mucin MUC4 and its membrane partner ErbB2 regulate biological properties of human CAPAN-2 pancreatic cancer cells via different signalling pathways. Plos One. 7: e32232. PMID 22393391 DOI: 10.1371/Journal.Pone.0032232 |
0.833 |
|
| 2011 |
Bruyère E, Jonckheere N, Frénois F, Mariette C, Van Seuningen I. The MUC4 membrane-bound mucin regulates esophageal cancer cell proliferation and migration properties: Implication for S100A4 protein. Biochemical and Biophysical Research Communications. 413: 325-9. PMID 21889495 DOI: 10.1016/J.Bbrc.2011.08.095 |
0.836 |
|
| 2011 |
Jonckheere N, Velghe A, Ducourouble MP, Copin MC, Renes IB, Van Seuningen I. The mouse Muc5b mucin gene is transcriptionally regulated by thyroid transcription factor-1 (TTF-1) and GATA-6 transcription factors. The Febs Journal. 278: 282-94. PMID 21126317 DOI: 10.1111/J.1742-4658.2010.07945.X |
0.639 |
|
| 2010 |
Jonckheere N, Skrypek N, Van Seuningen I. Mucins and pancreatic cancer. Cancers. 2: 1794-812. PMID 24281201 DOI: 10.3390/Cancers2041794 |
0.838 |
|
| 2010 |
Piessen G, Wacrenier A, Briez N, Triboulet JP, Van Seuningen I, Mariette C. Clinical impact of MUC1 and MUC4 expression in Barrett-associated oesophageal adenocarcinoma. Journal of Clinical Pathology. 62: 1144-6. PMID 19946103 DOI: 10.1136/Jcp.2008.060780 |
0.489 |
|
| 2010 |
Jonckheere N, Van Seuningen I. The membrane-bound mucins: From cell signalling to transcriptional regulation and expression in epithelial cancers. Biochimie. 92: 1-11. PMID 19818375 DOI: 10.1016/J.Biochi.2009.09.018 |
0.747 |
|
| 2009 |
Van Seuningen I, Vincent A. Mucins: a new family of epigenetic biomarkers in epithelial cancers. Expert Opinion On Medical Diagnostics. 3: 411-27. PMID 23485209 DOI: 10.1517/17530050902852697 |
0.711 |
|
| 2009 |
Jonckheere N, Fauquette V, Stechly L, Saint-Laurent N, Aubert S, Susini C, Huet G, Porchet N, Van Seuningen I, Pigny P. Tumour growth and resistance to gemcitabine of pancreatic cancer cells are decreased by AP-2alpha overexpression. British Journal of Cancer. 101: 637-44. PMID 19672266 DOI: 10.1038/Sj.Bjc.6605190 |
0.657 |
|
| 2009 |
Vincent A, Van Seuningen I. Epigenetics, stem cells and epithelial cell fate. Differentiation; Research in Biological Diversity. 78: 99-107. PMID 19632029 DOI: 10.1016/J.Diff.2009.07.002 |
0.67 |
|
| 2009 |
Burger-van Paassen N, Vincent A, Puiman PJ, van der Sluis M, Bouma J, Boehm G, van Goudoever JB, van Seuningen I, Renes IB. The regulation of intestinal mucin MUC2 expression by short-chain fatty acids: implications for epithelial protection. The Biochemical Journal. 420: 211-9. PMID 19228118 DOI: 10.1042/Bj20082222 |
0.659 |
|
| 2008 |
Jonckheere N, Van Seuningen I. The membrane-bound mucins: how large O-glycoproteins play key roles in epithelial cancers and hold promise as biological tools for gene-based and immunotherapies. Critical Reviews in Oncogenesis. 14: 177-96. PMID 19409062 DOI: 10.1615/Critrevoncog.V14.I2-3.30 |
0.702 |
|
| 2008 |
Yamaguchi K, Cekanova M, McEntee MF, Yoon JH, Fischer SM, Renes IB, Van Seuningen I, Baek SJ. Peroxisome proliferator-activated receptor ligand MCC-555 suppresses intestinal polyps in ApcMin/+ mice via extracellular signal-regulated kinase and peroxisome proliferator-activated receptor-dependent pathways Molecular Cancer Therapeutics. 7: 2779-2787. PMID 18790758 DOI: 10.1158/1535-7163.MCT-08-0173 |
0.331 |
|
| 2008 |
Mejías-Luque R, Peiró S, Vincent A, Van Seuningen I, de Bolós C. IL-6 induces MUC4 expression through gp130/STAT3 pathway in gastric cancer cell lines. Biochimica Et Biophysica Acta. 1783: 1728-36. PMID 18573283 DOI: 10.1016/J.Bbamcr.2008.05.020 |
0.655 |
|
| 2008 |
Barros R, Pereira B, Duluc I, Azevedo M, Mendes N, Camilo V, Jacobs RJ, Paulo P, Santos-Silva F, van Seuningen I, van den Brink GR, David L, Freund JN, Almeida R. Key elements of the BMP/SMAD pathway co-localize with CDX2 in intestinal metaplasia and regulate CDX2 expression in human gastric cell lines. The Journal of Pathology. 215: 411-20. PMID 18498120 DOI: 10.1002/path.2369 |
0.329 |
|
| 2008 |
Vincent A, Ducourouble MP, Van Seuningen I. Epigenetic regulation of the human mucin gene MUC4 in epithelial cancer cell lines involves both DNA methylation and histone modifications mediated by DNA methyltransferases and histone deacetylases. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3035-45. PMID 18492726 DOI: 10.1096/Fj.07-103390 |
0.703 |
|
| 2008 |
van der Sluis M, Bouma J, Vincent A, Velcich A, Carraway KL, Büller HA, Einerhand AW, van Goudoever JB, Van Seuningen I, Renes IB. Combined defects in epithelial and immunoregulatory factors exacerbate the pathogenesis of inflammation: mucin 2-interleukin 10-deficient mice. Laboratory Investigation; a Journal of Technical Methods and Pathology. 88: 634-42. PMID 18427556 DOI: 10.1038/Labinvest.2008.28 |
0.599 |
|
| 2008 |
van der Sluis M, Vincent A, Bouma J, Korteland-Van Male A, van Goudoever JB, Renes IB, Van Seuningen I. Forkhead box transcription factors Foxa1 and Foxa2 are important regulators of Muc2 mucin expression in intestinal epithelial cells. Biochemical and Biophysical Research Communications. 369: 1108-13. PMID 18336786 DOI: 10.1016/J.Bbrc.2008.02.158 |
0.686 |
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| 2008 |
Mariette C, Piessen G, Leteurtre E, Hémon B, Triboulet JP, Van Seuningen I. Activation of MUC1 mucin expression by bile acids in human esophageal adenocarcinomatous cells and tissues is mediated by the phosphatidylinositol 3-kinase. Surgery. 143: 58-71. PMID 18154934 DOI: 10.1016/J.Surg.2007.07.043 |
0.572 |
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| 2008 |
Groux-Degroote S, Krzewinski-Recchi MA, Cazet A, Vincent A, Lehoux S, Lafitte JJ, Van Seuningen I, Delannoy P. IL-6 and IL-8 increase the expression of glycosyltransferases and sulfotransferases involved in the biosynthesis of sialylated and/or sulfated Lewisx epitopes in the human bronchial mucosa. The Biochemical Journal. 410: 213-23. PMID 17944600 DOI: 10.1042/Bj20070958 |
0.617 |
|
| 2007 |
Fauquette V, Aubert S, Groux-Degroote S, Hemon B, Porchet N, Van Seuningen I, Pigny P. Transcription factor AP-2alpha represses both the mucin MUC4 expression and pancreatic cancer cell proliferation. Carcinogenesis. 28: 2305-12. PMID 17621592 DOI: 10.1093/carcin/bgm158 |
0.354 |
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| 2007 |
Jonckheere N, Vincent A, Perrais M, Ducourouble MP, Male AK, Aubert JP, Pigny P, Carraway KL, Freund JN, Renes IB, Van Seuningen I. The human mucin MUC4 is transcriptionally regulated by caudal-related homeobox, hepatocyte nuclear factors, forkhead box A, and GATA endodermal transcription factors in epithelial cancer cells. The Journal of Biological Chemistry. 282: 22638-50. PMID 17553805 DOI: 10.1074/Jbc.M700905200 |
0.799 |
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| 2007 |
Piessen G, Jonckheere N, Vincent A, Hémon B, Ducourouble MP, Copin MC, Mariette C, Van Seuningen I. Regulation of the human mucin MUC4 by taurodeoxycholic and taurochenodeoxycholic bile acids in oesophageal cancer cells is mediated by hepatocyte nuclear factor 1alpha. The Biochemical Journal. 402: 81-91. PMID 17037983 DOI: 10.1042/Bj20061461 |
0.805 |
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| 2006 |
Rat E, Billaut-Laden I, Allorge D, Lo-Guidice JM, Tellier M, Cauffiez C, Jonckheere N, van Seuningen I, Lhermitte M, Romano A, Guéant JL, Broly F. Evidence for a functional genetic polymorphism of the human retinoic acid-metabolizing enzyme CYP26A1, an enzyme that may be involved in spina bifida. Birth Defects Research. Part a, Clinical and Molecular Teratology. 76: 491-8. PMID 16933217 DOI: 10.1002/Bdra.20275 |
0.605 |
|
| 2005 |
Mariette C, Finzi L, Piessen G, Van Seuningen I, Triboulet JP. Esophageal carcinoma: Prognostic differences between squamous cell carcinoma and adenocarcinoma World Journal of Surgery. 29: 39-45. PMID 15599738 DOI: 10.1007/S00268-004-7542-X |
0.487 |
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| 2005 |
Fauquette V, Perrais M, Cerulis S, Jonckheere N, Ducourouble MP, Aubert JP, Pigny P, Van Seuningen I. The antagonistic regulation of human MUC4 and ErbB-2 genes by the Ets protein PEA3 in pancreatic cancer cells: implications for the proliferation/differentiation balance in the cells. The Biochemical Journal. 386: 35-45. PMID 15461591 DOI: 10.1042/Bj20040706 |
0.744 |
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| 2005 |
Mariette C, Piessen G, Balon JM, Van Seuningen I, Triboulet JP. Surgery alone in the curative treatment of localised oesophageal carcinoma. European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. 30: 869-76. PMID 15336734 DOI: 10.1016/J.Ejso.2004.06.009 |
0.4 |
|
| 2004 |
van der Sluis M, Melis MH, Jonckheere N, Ducourouble MP, Büller HA, Renes I, Einerhand AW, Van Seuningen I. The murine Muc2 mucin gene is transcriptionally regulated by the zinc-finger GATA-4 transcription factor in intestinal cells. Biochemical and Biophysical Research Communications. 325: 952-60. PMID 15541382 DOI: 10.1016/J.Bbrc.2004.10.108 |
0.696 |
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| 2004 |
Jonckheere N, Perrais M, Mariette C, Batra SK, Aubert JP, Pigny P, Van Seuningen I. A role for human MUC4 mucin gene, the ErbB2 ligand, as a target of TGF-beta in pancreatic carcinogenesis. Oncogene. 23: 5729-38. PMID 15184872 DOI: 10.1038/Sj.Onc.1207769 |
0.677 |
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| 2004 |
Mariette C, Perrais M, Leteurtre E, Jonckheere N, Hémon B, Pigny P, Batra S, Aubert JP, Triboulet JP, Van Seuningen I. Transcriptional regulation of human mucin MUC4 by bile acids in oesophageal cancer cells is promoter-dependent and involves activation of the phosphatidylinositol 3-kinase signalling pathway. The Biochemical Journal. 377: 701-8. PMID 14583090 DOI: 10.1042/Bj20031132 |
0.675 |
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| 2004 |
Jonckheere N, Van Der Sluis M, Velghe A, Buisine MP, Sutmuller M, Ducourouble MP, Pigny P, Büller HA, Aubert JP, Einerhand AW, Van Seuningen I. Transcriptional activation of the murine Muc5ac mucin gene in epithelial cancer cells by TGF-beta/Smad4 signalling pathway is potentiated by Sp1. The Biochemical Journal. 377: 797-808. PMID 14570593 DOI: 10.1042/Bj20030948 |
0.668 |
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| 2003 |
Mesquita P, Jonckheere N, Almeida R, Ducourouble MP, Serpa J, Silva E, Pigny P, Silva FS, Reis C, Silberg D, Van Seuningen I, David L. Human MUC2 mucin gene is transcriptionally regulated by Cdx homeodomain proteins in gastrointestinal carcinoma cell lines. The Journal of Biological Chemistry. 278: 51549-56. PMID 14525978 DOI: 10.1074/Jbc.M309019200 |
0.674 |
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| 2001 |
Perrais M, Pigny P, Ducourouble MP, Petitprez D, Porchet N, Aubert JP, Van Seuningen I. Characterization of human mucin gene MUC4 promoter: importance of growth factors and proinflammatory cytokines for its regulation in pancreatic cancer cells. The Journal of Biological Chemistry. 276: 30923-33. PMID 11418607 DOI: 10.1074/JBC.M104204200 |
0.317 |
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