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Betty Jean Gaffney, Ph.D. - Publications

Affiliations: 
1974-1996 Chemistry Johns Hopkins University, Baltimore, MD 
 1996- Biological Science Florida State University, Tallahassee, FL, United States 
Area:
Crystallography, EPR, NMR
Website:
http://www.bio.fsu.edu/faculty-gaffney.php
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56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Gaffney BJ. EPR Spectroscopic Studies of Lipoxygenases. Chemistry, An Asian Journal. PMID 31782616 DOI: 10.1002/Asia.201901461  0.384
2014 Gaffney BJ. Connecting lipoxygenase function to structure by electron paramagnetic resonance. Accounts of Chemical Research. 47: 3588-95. PMID 25341190 DOI: 10.1021/Ar500290R  0.436
2014 Bradshaw MD, Gaffney BJ. Fluctuations of an exposed π-helix involved in lipoxygenase substrate recognition. Biochemistry. 53: 5102-10. PMID 25036469 DOI: 10.1021/Bi500768C  0.788
2013 Garreta A, Val-Moraes SP, García-Fernández Q, Busquets M, Juan C, Oliver A, Ortiz A, Gaffney BJ, Fita I, Manresa À, Carpena X. Structure and interaction with phospholipids of a prokaryotic lipoxygenase from Pseudomonas aeruginosa. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 4811-21. PMID 23985801 DOI: 10.1096/Fj.13-235952  0.331
2012 Gaffney BJ, Bradshaw MD, Frausto SD, Wu F, Freed JH, Borbat P. Locating a lipid at the portal to the lipoxygenase active site. Biophysical Journal. 103: 2134-44. PMID 23200047 DOI: 10.1016/J.Bpj.2012.10.002  0.781
2012 Bradshaw MD, Gaffney BJ. Functional Conformational Changes in Lipoxygenase Biophysical Journal. 102: 63a. DOI: 10.1016/J.Bpj.2011.11.376  0.783
2011 Garreta A, García-Fernández Q, Busquets M, Manresa À, Pompeia do Val de Moraes S, Gaffney B, Fita I, Carpena X. Structure of a Prokaryotic Lipoxygenase Bound to a Phospholipid Biophysical Journal. 100: 50a. DOI: 10.1016/J.Bpj.2010.12.473  0.369
2010 Garreta A, Manresa À, Busquets M, Gaffney BJ. Conservation of Active Site Geometry in Evolution of Iron Lipoxygenases: EPR Studies Biophysical Journal. 98: 451a. DOI: 10.1016/J.Bpj.2009.12.2451  0.359
2009 Gaffney BJ, Wu F, Frausto SD. Interactions of Lipoxygenase with Paramagnetic Substrate Analogs Biophysical Journal. 96: 310a. DOI: 10.1016/J.Bpj.2008.12.1546  0.563
2007 Gaffney BJ. Anesthesia, analgesia, and euphoria. Biophysical Journal. 92: 1-2. PMID 17028147 DOI: 10.1529/Biophysj.106.096503  0.316
2006 Wu F, Gaffney BJ. Dynamic behavior of fatty acid spin labels within a binding site of soybean lipoxygenase-1. Biochemistry. 45: 12510-8. PMID 17029406 DOI: 10.1021/Bi061415L  0.54
2006 Youn B, Sellhorn GE, Mirchel RJ, Gaffney BJ, Grimes HD, Kang C. Crystal structures of vegetative soybean lipoxygenase VLX-B and VLX-D, and comparisons with seed isoforms LOX-1 and LOX-3. Proteins. 65: 1008-20. PMID 17022084 DOI: 10.1002/Prot.21182  0.319
2006 Gaffney BJ. Electron Spin Resonance of Biomolecules Reviews in Cell Biology and Molecular Medicine. DOI: 10.1002/3527600906.Mcb.200300104  0.34
2005 Coffa G, Imber AN, Maguire BC, Laxmikanthan G, Schneider C, Gaffney BJ, Brash AR. On the relationships of substrate orientation, hydrogen abstraction, and product stereochemistry in single and double dioxygenations by soybean lipoxygenase-1 and its Ala542Gly mutant. The Journal of Biological Chemistry. 280: 38756-66. PMID 16157595 DOI: 10.1074/Jbc.M504870200  0.727
2004 Agarwalla S, Stroud RM, Gaffney BJ. Redox reactions of the iron-sulfur cluster in a ribosomal RNA methyltransferase, RumA: optical and EPR studies. The Journal of Biological Chemistry. 279: 34123-9. PMID 15181002 DOI: 10.1074/Jbc.M405702200  0.304
2003 Wu F, Katsir LJ, Seavy M, Gaffney BJ. Role of radical formation at tyrosine 193 in the allene oxide synthase domain of a lipoxygenase-AOS fusion protein from coral. Biochemistry. 42: 6871-80. PMID 12779342 DOI: 10.1021/Bi027427Y  0.488
2001 Gaffney BJ, Su C, Oliw EH. Assignment of EPR Transitions in a Manganese-Containing Lipoxygenase and Prediction of Local Structure. Applied Magnetic Resonance. 21: 413-424. PMID 16518455 DOI: 10.1007/Bf03162417  0.386
2001 Abraham BD, Sono M, Boutaud O, Shriner A, Dawson JH, Brash AR, Gaffney BJ. Characterization of the coral allene oxide synthase active site with UV-visible absorption, magnetic circular dichroism, and electron paramagnetic resonance spectroscopy: evidence for tyrosinate ligation to the ferric enzyme heme iron. Biochemistry. 40: 2251-9. PMID 11329294 DOI: 10.1021/Bi002121H  0.399
1999 Grant CV, Cope W, Ball JA, Maresch GG, Gaffney BJ, Fink W, Britt RD. Electronic Structure of the Aqueous Vanadyl Ion Probed by 9 and 94 GHz EPR and Pulsed ENDOR Spectroscopies and Density Functional Theory Calculations. The Journal of Physical Chemistry. B. 103: 10627-31. PMID 16467924 DOI: 10.1021/jp992186y  0.667
1999 Bowers CR, Storhaug V, Webster CE, Bharatam J, Cottone A, Gianna R, Betsey K, Gaffney BJ. Exploring surfaces and cavities in lipoxygenase and other proteins by hyperpolarized xenon-129 NMR. Journal of the American Chemical Society. 121: 9370-7. PMID 16429610 DOI: 10.1021/Ja991443+  0.342
1998 Gaffney BJ, Eaton GR, Eaton SS. Electron Spin Relaxation Rates for High-Spin Fe(III) in Iron Transferrin Carbonate and Iron Transferrin Oxalate. The Journal of Physical Chemistry. B. 102: 5536-41. PMID 16429607 DOI: 10.1021/Jp981595B  0.365
1998 Gaffney BJ, Marsh D. High-frequency, spin-label EPR of nonaxial lipid ordering and motion in cholesterol-containing membranes. Proceedings of the National Academy of Sciences of the United States of America. 95: 12940-3. PMID 9789019 DOI: 10.1073/Pnas.95.22.12940  0.349
1998 Gaffney BJ, Silverstone HJ. Simulation methods for looping transitions. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 134: 57-66. PMID 9740731 DOI: 10.1006/Jmre.1998.1526  0.639
1998 Prigge ST, Gaffney BJ, Amzel LM. Relation between positional specificity and chirality in mammalian lipoxygenases. Nature Structural Biology. 5: 178-9. PMID 9501907 DOI: 10.1038/Nsb0398-178  0.341
1998 Gaffney BJ, Maguire BC, Weber RT, Maresch GG. Disorder at metal sites in proteins: A high-frequency-EMR study Applied Magnetic Resonance. 16: 207-221. DOI: 10.1007/Bf03161934  0.721
1997 Boyington JC, Gaffney BJ, Amzel LM. The three-dimensional structure of soybean lipoxygenase-1: an arachidonic acid 15-lipoxygenase. Advances in Experimental Medicine and Biology. 400: 133-8. PMID 9547548 DOI: 10.1007/978-1-4615-5325-0_19  0.657
1997 Prigge ST, Boyington JC, Faig M, Doctor KS, Gaffney BJ, Amzel LM. Structure and mechanism of lipoxygenases. Biochimie. 79: 629-36. PMID 9479444 DOI: 10.1016/S0300-9084(97)83495-5  0.775
1997 Maguire BC, Gaffney BJ. Interdoublet transitions in S = 5/2 protein systems. Solid State Nuclear Magnetic Resonance. 9: 81-3. PMID 9413907 DOI: 10.1016/S0926-2040(97)00047-7  0.741
1996 Gaffney BJ. Lipoxygenases: structural principles and spectroscopy. Annual Review of Biophysics and Biomolecular Structure. 25: 431-59. PMID 8800477 DOI: 10.1146/Annurev.Bb.25.060196.002243  0.419
1996 Prigge ST, Boyington JC, Gaffney BJ, Amzel LM. Structure conservation in lipoxygenases: structural analysis of soybean lipoxygenase-1 and modeling of human lipoxygenases. Proteins. 24: 275-91. PMID 8778775 DOI: 10.1002/(Sici)1097-0134(199603)24:3<275::Aid-Prot1>3.0.Co;2-G  0.655
1996 Doctor KS, Gaffney BJ. High frequency EPR predictions for the non-heme iron protein lipoxygenase Applied Magnetic Resonance. 11: 425-435. DOI: 10.1007/Bf03162238  0.783
1995 Gaffney BJ, Boyington JC, Amzel LM, Doctor KS, Prigge ST, Yuan SM. Lipoxygenase structure and mechanism. Advances in Prostaglandin, Thromboxane, and Leukotriene Research. 23: 11-6. PMID 7732813  0.753
1994 Boyington JC, Gaffney BJ, Amzel LM, Doctor KS, Mavrophilipos DV, Mavrophilipos ZV, Colom A, Yuan SM. The x-ray structure and biophysical studies of a 15-lipoxygenase. Annals of the New York Academy of Sciences. 744: 310-3. PMID 7825855 DOI: 10.1111/J.1749-6632.1994.Tb52749.X  0.663
1993 Thomas DD, Gaffney BJ, Griffith H. Harden M. McConnell: The Science Speaks for Itself. Biophysical Journal. 64: 573-6. PMID 19431875 DOI: 10.1016/S0006-3495(93)81415-2  0.348
1993 Boyington JC, Gaffney BJ, Amzel LM. The three-dimensional structure of an arachidonic acid 15-lipoxygenase. Science (New York, N.Y.). 260: 1482-6. PMID 8502991 DOI: 10.1126/Science.8502991  0.666
1993 Gaffney BJ, Mavrophilipos DV, Doctor KS. Access of ligands to the ferric center in lipoxygenase-1. Biophysical Journal. 64: 773-83. PMID 8386016 DOI: 10.1016/S0006-3495(93)81438-3  0.693
1993 Boyington JC, Gaffney BJ, Amzel LM. Structure of soybean lipoxygenase-I. Biochemical Society Transactions. 21: 744-8. PMID 8224502 DOI: 10.1042/Bst0210744  0.623
1993 Doctor KS, Gaffney BJ, Alvarez G, Silverstone HJ. EPR spectroscopy of interdoublet transitions in high-spin iron: Applications to transferrin oxalate Journal of Physical Chemistry. 97: 3028-3033. DOI: 10.1021/J100114A033  0.787
1993 Griffith OH, Gaffney BJ, Kwiram AL. Harden M. McConnell: a Celebration of His Scientific Achievements The Journal of Physical Chemistry. 97: 2805-2822. DOI: 10.1021/J100114A001  0.637
1990 Boyington JC, Gaffney BJ, Amzel LM. Crystallization and preliminary x-ray analysis of soybean lipoxygenase-1, a non-heme iron-containing dioxygenase. The Journal of Biological Chemistry. 265: 12771-3. PMID 2115880  0.618
1990 Yang AS, Gaffney BJ. EPR detection of kinetic responses to photochemically generated protein cofactors Journal of Magnetic Resonance (1969). 90: 580-583. DOI: 10.1016/0022-2364(90)90065-H  0.527
1987 Yang AS, Gaffney BJ. Determination of relative spin concentration in some high-spin ferric proteins using E/D-distribution in electron paramagnetic resonance simulations. Biophysical Journal. 51: 55-67. PMID 3026504 DOI: 10.1016/S0006-3495(87)83311-8  0.565
1986 Bloom LM, Benkovic SJ, Gaffney BJ. Characterization of phenylalanine hydroxylase. Biochemistry. 25: 4204-10. PMID 3019383 DOI: 10.1021/Bi00363A006  0.359
1984 Wallick DE, Bloom LM, Gaffney BJ, Benkovic SJ. Reductive activation of phenylalanine hydroxylase and its effect on the redox state of the non-heme iron. Biochemistry. 23: 1295-302. PMID 6324864 DOI: 10.1021/Bi00301A043  0.343
1983 Willingham GL, Gaffney BJ. Reactions of spin-label cross-linking reagents with red blood cell proteins. Biochemistry. 22: 892-8. PMID 6301529 DOI: 10.1021/Bi00273A028  0.77
1983 Gaffney BJ, Willingham GL, Schepp RS. Synthesis and membrane interactions of spin-label bifunctional reagents. Biochemistry. 22: 881-92. PMID 6301528 DOI: 10.1021/Bi00273A027  0.762
1982 Gaffney BJ, Scheule RK. What is a Successful Reconstitution of a Membrane Glycoprotein that Lacks an Enzymatic Activity? Biophysical Journal. 37: 81-2. PMID 19431514 DOI: 10.1016/S0006-3495(82)84610-9  0.558
1982 Chen SC, Sturtevant JM, Conklin K, Gaffney BJ. Calorimetric evidence for phase transitions in spin-label lipid bilayers. Biochemistry. 21: 5096-101. PMID 7138849 DOI: 10.1021/Bi00263A038  0.555
1981 Scheule RK, Gaffney BJ. Reconstitution of membranes with fractions of triton X-100 which are easily removed. Analytical Biochemistry. 117: 61-6. PMID 7316198 DOI: 10.1016/0003-2697(81)90691-6  0.593
1980 Gaffney BJ, Drachman DB, Lin DC, Tennekoon G. Spin-label studies of erythrocytes in myotonic dystrophy: no increase in membrane fluidity. Neurology. 30: 272-6. PMID 7189026 DOI: 10.1212/Wnl.30.3.272  0.597
1980 Chen SC, Sturtevant JM, Gaffney BJ. Scanning calorimetric evidence for a third phase transition in phosphatidylcholine bilayers. Proceedings of the National Academy of Sciences of the United States of America. 77: 5060-3. PMID 6933546 DOI: 10.1073/Pnas.77.9.5060  0.502
1979 Gaffney BJ. Spin label-thiourea adducts. A model for saturation transfer EPR studies of slow anisotropic rotation Journal of Physical Chemistry. 83: 3345-3349. DOI: 10.1021/J100489A007  0.325
1978 Chen SC, Gaffney BJ. Paramagnetic resonance evidence for phase transitions in bilayers of pure spin-labeled lipids Journal of Magnetic Resonance (1969). 29: 341-353. DOI: 10.1016/0022-2364(78)90158-0  0.545
1974 Gaffney BJ. [17] Spin-label measurements in membranes☆ Methods in Enzymology. 32: 161-198. DOI: 10.1016/0076-6879(74)32020-4  0.339
1974 Gaffney BJ, McConnell HM. The paramagnetic resonance spectra of spin labels in phospholipid membranes Journal of Magnetic Resonance (1969). 16: 1-28. DOI: 10.1016/0022-2364(74)90193-0  0.546
1974 Gaffney BJ, McConnell HM. Effect of a magnetic field on phospholipid membranes Chemical Physics Letters. 24: 310-313. DOI: 10.1016/0009-2614(74)85266-8  0.473
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