Sankar K. Guchhait - Publications

2007- National Institute of Pharmaceutical Education and Research, Mohali 
Synthetic organic chemistry, natural products chemistry, medicinal chemistry, anticancer drugs

27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Kumari A, Srivastava S, Manne RK, Sisodiya S, Santra MK, Guchhait SK, Panda D. C12, a combretastatin-A4 analog, exerts anticancer activity by targeting microtubules. Biochemical Pharmacology. 113663. PMID 31606408 DOI: 10.1016/j.bcp.2019.113663  0.72
2018 Hura N, Sawant AV, Kumari A, Guchhait SK, Panda D. Combretastatin-Inspired Heterocycles as Antitubulin Anticancer Agents. Acs Omega. 3: 9754-9769. PMID 31459105 DOI: 10.1021/acsomega.8b00996  0.72
2018 Tripathi N, Guchhait SK, Bharatam PV. Pharmacoinformatics analysis of merbarone binding site in human topoisomerase IIα. Journal of Molecular Graphics & Modelling. 86: 1-18. PMID 30296751 DOI: 10.1016/j.jmgm.2018.09.013  0.44
2018 Hura N, Naaz A, Prassanawar SS, Guchhait SK, Panda D. Drug-Clinical Agent Molecular Hybrid: Synthesis of Diaryl(trifluoromethyl)pyrazoles as Tubulin Targeting Anticancer Agents. Acs Omega. 3: 1955-1969. PMID 30023819 DOI: 10.1021/acsomega.7b01784  0.72
2018 Guchhait SK, Sisodiya S, Saini M, Shah YV, Kumar G, Daniel DP, Hura N, Chaudhary V. Synthesis of polyfunctionalized pyrroles via a tandem reaction of Michael addition and intramolecular cyanide-mediated nitrile-to-nitrile condensation. The Journal of Organic Chemistry. PMID 29671317 DOI: 10.1021/acs.joc.8b00465  0.72
2017 Guchhait SK, Saini M, Sumkaria D, Chaudhary V. A nitrile-stabilized ammonium ylide as a masked C-C[double bond, length as m-dash]N synthon in heterocyclization with amidine-imine: 3-component assembly to fused pyrimidine scaffolds. Chemical Communications (Cambridge, England). 53: 6941-6944. PMID 28612882 DOI: 10.1039/c7cc02946b  0.72
2017 Guchhait SK, Hura N, Shah AP. Synthesis of polysubstituted 2-aminoimidazoles via alkene-diamination of guanidine with conjugated α-bromoalkenones. The Journal of Organic Chemistry. PMID 28195472 DOI: 10.1021/acs.joc.6b03021  0.72
2016 Priyadarshani G, Nayak A, Amrutkar SM, Das S, Guchhait SK, Kundu CN, Banerjee UC. Scaffold-Hopping of Aurones: 2-Arylideneimidazo[1,2-a]pyridinones as Topoisomerase IIα-Inhibiting Anticancer Agents. Acs Medicinal Chemistry Letters. 7: 1056-1061. PMID 27994737 DOI: 10.1021/acsmedchemlett.6b00242  0.64
2016 Priyadarshani G, Amrutkar S, Nayak A, Banerjee UC, Kundu CN, Guchhait SK. Scaffold-hopping of bioactive flavonoids: Discovery of aryl-pyridopyrimidinones as potent anticancer agents that inhibit catalytic role of topoisomerase IIα. European Journal of Medicinal Chemistry. 122: 43-54. PMID 27343852 DOI: 10.1016/j.ejmech.2016.06.024  1
2016 Nandekar PP, Khomane K, Chaudhary V, Rathod VP, Borkar RM, Bhandi MM, Srinivas R, Sangamwar AT, Guchhait SK, Bansal AK. Identification of leads for antiproliferative activity on MDA-MB-435 human breast cancer cells through pharmacophore and CYP1A1-mediated metabolism. European Journal of Medicinal Chemistry. 115: 82-93. PMID 26994845 DOI: 10.1016/j.ejmech.2016.02.061  1
2016 Guchhait SK, Chaudhary V, Rana VA, Priyadarshani G, Kandekar S, Kashyap M. Oxidative Dearomatization of Indoles via Pd-Catalyzed C-H Oxygenation: An Entry to C2-Quaternary Indolin-3-ones. Organic Letters. 18: 1534-7. PMID 26986450 DOI: 10.1021/acs.orglett.6b00244  1
2016 Chaudhary V, Venghateri JB, Dhaked HP, Bhoyar AS, Guchhait SK, Panda D. Novel Combretastatin-2-aminoimidazole Analogues as Potent Tubulin Assembly Inhibitors: Exploration of Unique Pharmacophoric Impact of Bridging Skeleton and Aryl Moiety. Journal of Medicinal Chemistry. 59: 3439-51. PMID 26938120 DOI: 10.1021/acs.jmedchem.6b00101  1
2015 Guchhait SK, Priyadarshani G. Pd-Catalyzed Ag(I)-Promoted C3-Arylation of Pyrido[1,2-a]pyrimidin-4-ones with Bromo/Iodo-Arenes Journal of Organic Chemistry. 80: 8482-8488. PMID 26247916 DOI: 10.1021/acs.joc.5b01573  1
2015 Guchhait SK, Priyadarshani G. Synthesis of 2-Arylpyridopyrimidinones, 6-Aryluracils, and Tri- and Tetrasubstituted Conjugated Alkenes via Pd-Catalyzed Enolic C-O Bond Activation-Arylation Journal of Organic Chemistry. 80: 6342-6349. PMID 25996549 DOI: 10.1021/acs.joc.5b00771  1
2015 Baviskar AT, Amrutkar SM, Trivedi N, Chaudhary V, Nayak A, Guchhait SK, Banerjee UC, Bharatam PV, Kundu CN. Switch in Site of Inhibition: A Strategy for Structure-Based Discovery of Human Topoisomerase IIα Catalytic Inhibitors. Acs Medicinal Chemistry Letters. 6: 481-5. PMID 25941559 DOI: 10.1021/acsmedchemlett.5b00040  1
2014 Guchhait SK, Chaudhary V. Desilylative activation of TMSCN in chemoselective Strecker-Ugi type reaction: Functional fused imidazoles as building blocks as an entry route to annulated purines Organic and Biomolecular Chemistry. 12: 6694-6705. PMID 25032666 DOI: 10.1039/c4ob00882k  1
2013 Kandekar S, Preet R, Kashyap M, Prasad M. U. R, Mohapatra P, Das D, Satapathy SR, Siddharth S, Jain V, Choudhuri M, Kundu CN, Guchhait SK, Bharatam PV. Structural elaboration of a natural product: Identification of 3,3′-diindolylmethane aminophosphonate and urea derivatives as potent anticancer agents Chemmedchem. 8: 1873-1884. PMID 23983049 DOI: 10.1002/cmdc.201300273  1
2013 Kashyap M, Kandekar S, Baviskar AT, Das D, Preet R, Mohapatra P, Satapathy SR, Siddharth S, Guchhait SK, Kundu CN, Banerjee UC. Indenoindolone derivatives as topoisomerase II-inhibiting anticancer agents. Bioorganic & Medicinal Chemistry Letters. 23: 934-8. PMID 23321564 DOI: 10.1016/j.bmcl.2012.12.063  1
2012 Guchhait SK, Kandekar S, Kashyap M, Taxak N, Bharatam PV. C - H bond functionalization under metalation - Deprotonation process: Regioselective direct arylation of 3-aminoimidazo[1,2-a]pyrazine Journal of Organic Chemistry. 77: 8321-8328. PMID 22928611 DOI: 10.1021/jo301065s  1
2012 Guchhait SK, Chandgude AL, Priyadarshani G. CuSO4-glucose for in situ generation of controlled Cu(I)-Cu(II) bicatalysts: multicomponent reaction of heterocyclic azine and aldehyde with alkyne, and cycloisomerization toward synthesis of N-fused imidazoles. The Journal of Organic Chemistry. 77: 4438-44. PMID 22486279 DOI: 10.1021/jo3003024  0.64
2012 Kashyap M, Das D, Preet R, Mohapatra P, Satapathy SR, Siddharth S, Kundu CN, Guchhait SK. Scaffold hybridization in generation of indenoindolones as anticancer agents that induce apoptosis with cell cycle arrest at G2/M phase Bioorganic and Medicinal Chemistry Letters. 22: 2474-2479. PMID 22381050 DOI: 10.1016/j.bmcl.2012.02.007  1
2011 Baviskar AT, Madaan C, Preet R, Mohapatra P, Jain V, Agarwal A, Guchhait SK, Kundu CN, Banerjee UC, Bharatam PV. N-fused imidazoles as novel anticancer agents that inhibit catalytic activity of topoisomerase IIα and induce apoptosis in G1/S phase. Journal of Medicinal Chemistry. 54: 5013-30. PMID 21644529 DOI: 10.1021/jm200235u  1
2011 Guchhait SK, Kashyap M, Kamble H. ZrCl4-mediated regio- and chemoselective friedel-crafts acylation of indole Journal of Organic Chemistry. 76: 4753-4758. PMID 21526849 DOI: 10.1021/jo200561f  1
2010 Guchhait SK, Madaan C. Towards molecular diversity: Dealkylation of tert-butyl amine in Ugi-type multicomponent reaction product establishes tert-butyl isocyanide as a useful convertible isonitrile Organic and Biomolecular Chemistry. 8: 3631-3634. PMID 20574586 DOI: 10.1039/c0ob00022a  1
2008 Beshir AB, Guchhait SK, Gascón JA, Fenteany G. Synthesis and structure-activity relationships of metal-ligand complexes that potently inhibit cell migration. Bioorganic & Medicinal Chemistry Letters. 18: 498-504. PMID 18240381 DOI: 10.1016/j.bmcl.2007.11.099  1
2003 Kabalka GW, Guchhait SK. Synthesis of diprotected monosubstituted hydrazine derivatives from tert-butyl carbazates and boronic acids. Organic Letters. 5: 4129-31. PMID 14572266 DOI: 10.1021/ol035544v  1
2003 Kabalka GW, Guchhait SK. Synthesis of (e)- and (z)- alkenylphosphonates using vinylboronates. Organic Letters. 5: 729-31. PMID 12605501 DOI: 10.1021/ol027515a  1
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