Dennis W. Wolan - Publications

Affiliations: 
Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
Chemical biology, structural biology

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Garnar-Wortzel L, Bishop TR, Kitamura S, Milosevich N, Asiaban JN, Zhang X, Zheng Q, Chen E, Ramos AR, Ackerman CJ, Hampton EN, Chatterjee AK, Young TS, Hull MV, Sharpless KB, ... ... Wolan DW, et al. Chemical Inhibition of ENL/AF9 YEATS Domains in Acute Leukemia. Acs Central Science. 7: 815-830. PMID 34079898 DOI: 10.1021/acscentsci.0c01550  0.01
2021 Takamura A, Thuy-Boun PS, Kitamura S, Han Z, Wolan DW. A photoaffinity probe that targets folate-binding proteins. Bioorganic & Medicinal Chemistry Letters. 127903. PMID 33713779 DOI: 10.1016/j.bmcl.2021.127903  0.01
2021 Han Z, Thuy-Boun PS, Pfeiffer W, Vartabedian VF, Torkamani A, Teijaro JR, Wolan DW. Identification of an N-acetylneuraminic acid-presenting bacteria isolated from a human microbiome. Scientific Reports. 11: 4763. PMID 33637779 DOI: 10.1038/s41598-021-83875-w  0.01
2021 Thuy-Boun PS, Mehta S, Gruening B, McGowan T, Nguyen A, Rajczewski AT, Johnson JE, Griffin TJ, Wolan DW, Jagtap PD. Metaproteomics Analysis of SARS-CoV-2-Infected Patient Samples Reveals Presence of Potential Coinfecting Microorganisms. Journal of Proteome Research. PMID 33393790 DOI: 10.1021/acs.jproteome.0c00822  0.01
2020 Flood DT, Knouse KW, Vantourout JC, Kitamura S, Sanchez BB, Sturgell EJ, Chen JS, Wolan DW, Baran PS, Dawson PE. Correction to "Synthetic Elaboration of Native DNA by RASS (SENDR)". Acs Central Science. 6: 2117. PMID 33274288 DOI: 10.1021/acscentsci.0c01389  0.01
2020 Flood DT, Knouse KW, Vantourout JC, Kitamura S, Sanchez BB, Sturgell EJ, Chen JS, Wolan DW, Baran PS, Dawson PE. Synthetic Elaboration of Native DNA by RASS (SENDR). Acs Central Science. 6: 1789-1799. PMID 33145415 DOI: 10.1021/acscentsci.0c00680  0.01
2020 Chin EN, Yu C, Vartabedian VF, Jia Y, Kumar M, Gamo AM, Vernier W, Ali SH, Kissai M, Lazar DC, Nguyen N, Pereira LE, Benish B, Woods AK, Joseph SB, ... ... Wolan DW, et al. Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic. Science (New York, N.Y.). 369: 993-999. PMID 32820126 DOI: 10.1126/Science.Abb4255  0.01
2020 Woehl JL, Kitamura S, Dillon N, Han Z, Edgar LJ, Nizet V, Wolan DW. An irreversible inhibitor to probe the role of cysteine protease SpeB in evasion of host complement defenses. Acs Chemical Biology. PMID 32662975 DOI: 10.1021/Acschembio.0C00191  0.04
2020 Kok BP, Ghimire S, Kim W, Chatterjee S, Johns T, Kitamura S, Eberhardt J, Ogasawara D, Xu J, Sukiasyan A, Kim SM, Godio C, Bittencourt JM, Cameron M, Galmozzi A, ... ... Wolan DW, et al. Discovery of small-molecule enzyme activators by activity-based protein profiling. Nature Chemical Biology. PMID 32514184 DOI: 10.1038/S41589-020-0555-4  1
2020 Kitamura S, Zheng Q, Woehl JL, Solania A, Chen E, Dillon N, Hull MV, Kotaniguchi M, Cappiello JR, Kitamura S, Nizet V, Sharpless KB, Wolan DW. SuFEx-enabled high-throughput medicinal chemistry. Journal of the American Chemical Society. PMID 32479075 DOI: 10.1021/Jacs.9B13652  0.01
2020 Xu JH, Eberhardt J, Hill-Payne B, Gonzalez-Paez GE, Castellón JO, Cravatt BF, Forli S, Wolan DW, Backus KM. Integrative x-ray structure and molecular modeling for the rationalization of procaspase-8 inhibitor potency and selectivity. Acs Chemical Biology. PMID 31927936 DOI: 10.1021/Acschembio.0C00019  1
2020 Mehta S, McGowan T, Johnson JE, Kumar P, Sajulga R, Arntzen M, Delogu F, Crane M, Thuy-Boun PS, Wolan DW, Griffin TJ, Jagtap PD. Evaluating customized database generation methods for metaproteomics analysis. F1000research. 9. DOI: 10.7490/F1000Research.1118252.1  0.01
2019 Bess EN, Bisanz JE, Yarza F, Bustion A, Rich BE, Li X, Kitamura S, Waligurski E, Ang QY, Alba DL, Spanogiannopoulos P, Nayfach S, Koliwad SK, Wolan DW, Franke AA, et al. Genetic basis for the cooperative bioactivation of plant lignans by Eggerthella lenta and other human gut bacteria. Nature Microbiology. PMID 31686027 DOI: 10.1038/S41564-019-0596-1  0.01
2019 Zheng Q, Woehl JL, Kitamura S, Santos-Martins D, Smedley CJ, Li G, Forli S, Moses JE, Wolan DW, Sharpless KB. SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase. Proceedings of the National Academy of Sciences of the United States of America. PMID 31484779 DOI: 10.1073/Pnas.1909972116  0.01
2019 Gordon MH, Anowai A, Young D, Das N, Campden RI, Sekhon H, Myers Z, Mainoli B, Chopra S, Thuy-Boun PS, Kizhakkedathu J, Bindra G, Jijon HB, Heitman S, Yates R, ... Wolan DW, et al. N-terminomics/TAILS profiling of proteases and their substrates in ulcerative colitis. Acs Chemical Biology. PMID 31393699 DOI: 10.1021/Acschembio.9B00608  0.01
2019 Thuy-Boun PS, Wolan DW. A glycal-based photoaffinity probe that enriches sialic acid binding proteins. Bioorganic & Medicinal Chemistry Letters. PMID 31387789 DOI: 10.1016/J.Bmcl.2019.07.054  0.01
2019 Solania A, González-Páez GE, Wolan DW. Selective and Rapid Cell-Permeable Inhibitor of Human Caspase-3. Acs Chemical Biology. PMID 31334631 DOI: 10.1021/Acschembio.9B00564  1
2019 González-Páez GE, Roncase EJ, Wolan DW. X-ray structure of an inactive zymogen clostripain-like protease from Parabacteroides distasonis. Acta Crystallographica. Section D, Structural Biology. 75: 325-332. PMID 30950403 DOI: 10.1107/S2059798319000809  1
2019 Roncase EJ, González-Páez GE, Wolan DW. X-ray structures of two Bacteroides thetaiotaomicron C11 proteases in complex with peptide-based inhibitors. Biochemistry. PMID 30835452 DOI: 10.1021/Acs.Biochem.9B00098  1
2019 Vasylieva N, Kitamura S, Dong J, Barnych B, Hvorecny KL, Madden DR, Gee SJ, Wolan DW, Morisseau C, Hammock BD. Nanobody-based binding assay for the discovery of potent inhibitors of CFTR inhibitory factor (Cif). Analytica Chimica Acta. 1057: 106-113. PMID 30832908 DOI: 10.1016/J.Aca.2018.12.060  0.01
2018 Park SR, Jung T, Thuy-Boun PS, Wang AY, Yates JR, Wolan DW. ComPIL 2.0: An Updated Comprehensive Metaproteomics Database. Journal of Proteome Research. PMID 30525664 DOI: 10.1021/Acs.Jproteome.8B00722  1
2018 Deutsch EW, Perez-Riverol Y, Chalkley RJ, Wilhelm M, Tate S, Sachsenberg T, Walzer M, Käll L, Delanghe B, Böcker S, Schymanski EL, Wilmes P, Dorfer V, Kuster B, Volders PJ, ... ... Wolan DW, et al. Expanding the use of spectral libraries in proteomics. Journal of Proteome Research. PMID 30270626 DOI: 10.1021/Acs.Jproteome.8B00485  1
2018 Xu JH, Jiang Z, Solania A, Chatterjee S, Suzuki B, Lietz CB, Hook VYH, O'Donoghue AJ, Wolan DW. A Commensal Dipeptidyl Aminopeptidase with Specificity for N-terminal Glycine Degrades Human-produced Antimicrobial Peptides In Vitro. Acs Chemical Biology. PMID 30085657 DOI: 10.1021/Acschembio.8B00420  0.12
2018 Xu JH, Jiang Z, Solania A, Chatterjee S, Suzuki B, Lietz CB, Hook VYH, O'Donoghue AJ, Wolan DW. A Commensal Dipeptidyl Aminopeptidase with Specificity for N-terminal Glycine Degrades Human-produced Antimicrobial Peptides In Vitro. Acs Chemical Biology. PMID 30085657 DOI: 10.1021/Acschembio.8B00420  0.12
2018 Balskus EP, Turnbaugh PJ, Wolan DW. Announcement of 2019 Keystone Symposia Conference: "Microbiome: Chemical Mechanisms and Biological Consequences". Msystems. 3. PMID 30057942 DOI: 10.1128/mSystems.00115-18  0.01
2018 Balskus EP, Turnbaugh PJ, Wolan DW. Announcement of 2019 Keystone Symposia Conference: "Microbiome: Chemical Mechanisms and Biological Consequences". Msystems. 3. PMID 30057942 DOI: 10.1128/mSystems.00115-18  0.01
2018 Wang AY, Thuy-Boun PS, Stupp GS, Su AI, Wolan DW. Triflic Acid Treatment Enables LC-MS/MS Analysis of Insoluble Bacterial Biomass. Journal of Proteome Research. 17: 2978-2986. PMID 30019906 DOI: 10.1021/Acs.Jproteome.8B00166  1
2018 Kitamura S, Wolan DW. Probing substrate recognition of bacterial lipoprotein signal peptidase using FRET reporters. Febs Letters. PMID 29885279 DOI: 10.1002/1873-3468.13155  0.01
2018 Guijas C, Montenegro-Burke JR, Domingo-Almenara X, Palermo A, Warth B, Hermann G, Koellensperger G, Huan T, Uritboonthai W, Aisporna AE, Wolan DW, Spilker ME, Benton HP, Siuzdak G. METLIN: A Technology Platform for Identifying Knowns and Unknowns. Analytical Chemistry. PMID 29381867 DOI: 10.1021/Acs.Analchem.7B04424  0.01
2018 Kitamura S, Owensby A, Wall D, Wolan DW. Lipoprotein Signal Peptidase Inhibitors with Antibiotic Properties Identified through Design of a Robust In Vitro HT Platform. Cell Chemical Biology. PMID 29337186 DOI: 10.1016/J.Chembiol.2017.12.011  0.01
2018 Moon C, Stupp GS, Su AI, Wolan DW. Metaproteomics of Colonic Microbiota Unveils Discrete Protein Functions among Colitic Mice and Control Groups. Proteomics. 18. PMID 29319931 DOI: 10.1002/Pmic.201700391  0.01
2017 Wright ZVF, Wu NC, Kadam RU, Wilson IA, Wolan DW. Structure-based optimization and synthesis of antiviral drug Arbidol analogues with significantly improved affinity to influenza hemagglutinin. Bioorganic & Medicinal Chemistry Letters. PMID 28689973 DOI: 10.1016/J.Bmcl.2017.06.074  1
2017 Roncase EJ, Moon C, Chatterjee S, González-Páez GE, Craik CS, O'Donoghue AJ, Wolan DW. Substrate Profiling and High Resolution Co-complex Crystal Structure of a Secreted C11 Protease Conserved Across Commensal Bacteria. Acs Chemical Biology. PMID 28414448 DOI: 10.1021/Acschembio.7B00143  1
2017 Mayers MD, Moon C, Stupp GS, Su AI, Wolan DW. Quantitative Metaproteomics and Activity-Based Probe Enrichment Reveals Significant Alterations in Protein Expression from a Mouse Model of Inflammatory Bowel Disease. Journal of Proteome Research. 16: 1014-1026. PMID 28052195 DOI: 10.1021/Acs.Jproteome.6B00938  0.01
2016 Chatterjee S, Stupp GS, Park SK, Ducom JC, Yates JR, Su AI, Wolan DW. A comprehensive and scalable database search system for metaproteomics. Bmc Genomics. 17: 642. PMID 27528457 DOI: 10.1186/S12864-016-2855-3  0.01
2016 Tada N, Jansen DJ, Mower MP, Blewett MM, Umotoy JC, Cravatt BF, Wolan DW, Shenvi RA. Synthesis and Sulfur Electrophilicity of the Nuphar Thiaspirane Pharmacophore. Acs Central Science. 2: 401-8. PMID 27413784 DOI: 10.1021/Acscentsci.6B00113  1
2016 Backus KM, Correia BE, Lum KM, Forli S, Horning BD, González-Páez GE, Chatterjee S, Lanning BR, Teijaro JR, Olson AJ, Wolan DW, Cravatt BF. Proteome-wide covalent ligand discovery in native biological systems. Nature. PMID 27309814 DOI: 10.1038/Nature18002  1
2015 Wang AY, González-Páez GE, Wolan DW. Identification and co-complex structure of a new S. pyogenes SpeB small molecule inhibitor. Biochemistry. PMID 26132413 DOI: 10.1021/Acs.Biochem.5B00607  1
2015 Assem N, Ferreira DJ, Wolan DW, Dawson PE. Acetone-Linked Peptides: A Convergent Approach for Peptide Macrocyclization and Labeling. Angewandte Chemie (International Ed. in English). PMID 26096515 DOI: 10.1002/Anie.201502607  1
2015 Wan KK, Iwasaki K, Umotoy JC, Wolan DW, Shenvi RA. Nitrosopurines en route to potently cytotoxic asmarines. Angewandte Chemie (International Ed. in English). 54: 2410-5. PMID 25580910 DOI: 10.1002/Anie.201411493  1
2014 Vickers CJ, González-Páez GE, Wolan DW. Discovery of a highly selective caspase-3 substrate for imaging live cells. Acs Chemical Biology. 9: 2199-203. PMID 25133295 DOI: 10.1021/Cb500586P  1
2014 Vickers CJ, González-Páez GE, Litwin KM, Umotoy JC, Coutsias EA, Wolan DW. Selective inhibition of initiator versus executioner caspases using small peptides containing unnatural amino acids. Acs Chemical Biology. 9: 2194-8. PMID 25079698 DOI: 10.1021/Cb5004256  1
2013 Vickers CJ, González-Páez GE, Wolan DW. Selective detection and inhibition of active caspase-3 in cells with optimized peptides. Journal of the American Chemical Society. 135: 12869-76. PMID 23915420 DOI: 10.1021/Ja406399R  1
2013 Vickers CJ, González-Páez GE, Umotoy JC, Cayanan-Garrett C, Brown SJ, Wolan DW. Small-molecule procaspase activators identified using fluorescence polarization. Chembiochem : a European Journal of Chemical Biology. 14: 1419-22. PMID 23836614 DOI: 10.1002/Cbic.201300315  1
2013 Vickers CJ, González-Páez GE, Wolan DW. Selective detection of caspase-3 versus caspase-7 using activity-based probes with key unnatural amino acids. Acs Chemical Biology. 8: 1558-66. PMID 23614665 DOI: 10.1021/Cb400209W  1
2012 Zorn JA, Wolan DW, Agard NJ, Wells JA. Fibrils colocalize caspase-3 with procaspase-3 to foster maturation. The Journal of Biological Chemistry. 287: 33781-95. PMID 22872644 DOI: 10.1074/Jbc.M112.386128  1
2012 González-Páez GE, Wolan DW. Ultrahigh and high resolution structures and mutational analysis of monomeric Streptococcus pyogenes SpeB reveal a functional role for the glycine-rich C-terminal loop. The Journal of Biological Chemistry. 287: 24412-26. PMID 22645124 DOI: 10.1074/Jbc.M112.361576  1
2011 Zorn JA, Wille H, Wolan DW, Wells JA. Self-assembling small molecules form nanofibrils that bind procaspase-3 to promote activation. Journal of the American Chemical Society. 133: 19630-3. PMID 22066605 DOI: 10.1021/Ja208350U  1
2011 Sadowsky JD, Burlingame MA, Wolan DW, McClendon CL, Jacobson MP, Wells JA. Turning a protein kinase on or off from a single allosteric site via disulfide trapping. Proceedings of the National Academy of Sciences of the United States of America. 108: 6056-61. PMID 21430264 DOI: 10.1073/Pnas.1102376108  1
2011 Pérez-Payá E, Orzáez M, Mondragón L, Wolan D, Wells JA, Messeguer A, Vicent MJ. Molecules that modulate Apaf-1 activity. Medicinal Research Reviews. 31: 649-75. PMID 20099266 DOI: 10.1002/Med.20198  1
2010 Wells JA, Wolan D, Zorn J, Datta D, Gray D, Sadowsky J. Abstract SY11-03: Turning enzymes on with small molecules Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Sy11-03  1
2009 Wolan DW, Zorn JA, Gray DC, Wells JA. Small-molecule activators of a proenzyme. Science (New York, N.Y.). 326: 853-8. PMID 19892984 DOI: 10.1126/Science.1177585  1
2004 Li C, Xu L, Wolan DW, Wilson IA, Olson AJ. Virtual screening of human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase against the NCI diversity set by use of AutoDock to identify novel nonfolate inhibitors. Journal of Medicinal Chemistry. 47: 6681-90. PMID 15615517 DOI: 10.1021/Jm049504O  1
2004 Cheong CG, Wolan DW, Greasley SE, Horton PA, Beardsley GP, Wilson IA. Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates. The Journal of Biological Chemistry. 279: 18034-45. PMID 14966129 DOI: 10.1074/Jbc.M313691200  1
2004 Wolan DW, Cheong CG, Greasley SE, Wilson IA. Structural insights into the human and avian IMP cyclohydrolase mechanism via crystal structures with the bound XMP inhibitor. Biochemistry. 43: 1171-83. PMID 14756553 DOI: 10.1021/Bi030162I  1
2003 Wolan DW, Greasley SE, Wall MJ, Benkovic SJ, Wilson IA. Structure of avian AICAR transformylase with a multisubstrate adduct inhibitor beta-DADF identifies the folate binding site. Biochemistry. 42: 10904-14. PMID 12974624 DOI: 10.1021/Bi030106H  1
2002 Wolan DW, Greasley SE, Beardsley GP, Wilson IA. Structural insights into the avian AICAR transformylase mechanism. Biochemistry. 41: 15505-13. PMID 12501179 DOI: 10.1021/Bi020505X  1
2001 Wolan DW, Teyton L, Rudolph MG, Villmow B, Bauer S, Busch DH, Wilson IA. Crystal structure of the murine NK cell-activating receptor NKG2D at 1.95 A. Nature Immunology. 2: 248-54. PMID 11224525 DOI: 10.1038/85311  1
1999 Ghosh DK, Crane BR, Ghosh S, Wolan D, Gachhui R, Crooks C, Presta A, Tainer JA, Getzoff ED, Stuehr DJ. Inducible nitric oxide synthase: role of the N-terminal beta-hairpin hook and pterin-binding segment in dimerization and tetrahydrobiopterin interaction. The Embo Journal. 18: 6260-70. PMID 10562538 DOI: 10.1093/Emboj/18.22.6260  1
1999 Ghosh S, Wolan D, Adak S, Crane BR, Kwon NS, Tainer JA, Getzoff ED, Stuehr DJ. Mutational analysis of the tetrahydrobiopterin-binding site in inducible nitric-oxide synthase. The Journal of Biological Chemistry. 274: 24100-12. PMID 10446182 DOI: 10.1074/Jbc.274.34.24100  1
1999 Sennequier N, Wolan D, Stuehr DJ. Antifungal imidazoles block assembly of inducible NO synthase into an active dimer Journal of Biological Chemistry. 274: 930-938. PMID 9873034 DOI: 10.1074/Jbc.274.2.930  1
1998 Siddhanta U, Presta A, Fan B, Wolan D, Rousseau DL, Stuehr DJ. Domain swapping in inducible nitric-oxide synthase: Electron transfer occurs between flavin and heme groups located on adjacent subunits in the dimer Journal of Biological Chemistry. 273: 18950-18958. PMID 9668073 DOI: 10.1074/Jbc.273.30.18950  1
Show low-probability matches.