Xin Linghu, Ph.D. - Publications

Affiliations: 
Chemistry Genentech, San Francisco, CA, United States 
Area:
organic chemistry

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Wong B, Linghu X, Crawford JJ, Drobnick J, Lee W, Zhang H. A chemoselective Reformatsky-Negishi approach to α-haloaryl esters Tetrahedron. 70: 1508-1515. DOI: 10.1016/j.tet.2013.12.053  1
2013 McLaughlin M, Belyk K, Chen CY, Linghu X, Pan J, Qian G, Reamer RA, Xu Y. Practical asymmetric synthesis of a chiral piperazinone derivative Organic Process Research and Development. 17: 1052-1060. DOI: 10.1021/op400150w  1
2012 Boyce GR, Greszler SN, Johnson JS, Linghu X, Malinowski JT, Nicewicz DA, Satterfield AD, Schmitt DC, Steward KM. Silyl glyoxylates. Conception and realization of flexible conjunctive reagents for multicomponent coupling. The Journal of Organic Chemistry. 77: 4503-15. PMID 22414181 DOI: 10.1021/jo300184h  1
2012 Goodyear A, Linghu X, Bishop B, Chen C, Cleator E, McLaughlin M, Sheen FJ, Stewart GW, Xu Y, Yin. J. Process development and large-scale synthesis of MK-6186, a non-nucleoside reverse transcriptase inhibitor for the treatment of HIV Organic Process Research and Development. 16: 605-611. DOI: 10.1021/op200334x  1
2012 Linghu X, McLaughlin M, Chen CY, Reamer RA, Dimichele L, Davies IW. Synthesis of functionalized 3-chloro-1-naphthols via Friedel-Crafts acylation of vinyl chlorides Tetrahedron Letters. 53: 1550-1552. DOI: 10.1016/j.tetlet.2012.01.011  1
2007 Linghu X, Kennedy-Smith JJ, Toste FD. Total synthesis of (+)-fawcettimine. Angewandte Chemie (International Ed. in English). 46: 7671-3. PMID 17729226 DOI: 10.1002/anie.200702695  1
2006 Staben ST, Linghu X, Toste FD. Enantioselective synthesis of gamma-hydroxyenones by chiral base-catalyzed Kornblum DeLaMare rearrangement. Journal of the American Chemical Society. 128: 12658-9. PMID 17002354 DOI: 10.1021/ja065464x  1
2006 Linghu X, Satterfield AD, Johnson JS. Symbiotic reagent activation: Oppenauer oxidation of magnesium alkoxides by silylglyoxylates triggers second-stage aldolization. Journal of the American Chemical Society. 128: 9302-3. PMID 16848444 DOI: 10.1021/ja062637+  1
2005 Nahm MR, Linghu X, Potnick JR, Yates CM, White PS, Johnson JS. Metallophosphite-induced nucleophilic acylation of alpha,beta-unsaturated amides: facilitated catalysis by a diastereoselective retro [1,4] Brook rearrangement. Angewandte Chemie (International Ed. in English). 44: 2377-9. PMID 15761891 DOI: 10.1002/anie.200462795  1
2005 Linghu X, Bausch CC, Johnson JS. Mechanism and scope of the cyanide-catalyzed cross silyl benzoin reaction. Journal of the American Chemical Society. 127: 1833-40. PMID 15701019 DOI: 10.1021/ja044086y  1
2004 Linghu X, Potnick JR, Johnson JS. Metallophosphites as umpolung catalysts: the enantioselective cross silyl benzoin reaction. Journal of the American Chemical Society. 126: 3070-1. PMID 15012135 DOI: 10.1021/ja0496468  1
2003 Linghu X, Johnson JS. Kinetic control in direct alpha-silyloxy ketone synthesis: a new regiospecific catalyzed cross silyl benzoin reaction. Angewandte Chemie (International Ed. in English). 42: 2534-6. PMID 12800180 DOI: 10.1002/anie.200250554  1
2002 Linghu X, Nicewicz DA, Johnson JS. Tandem carbon-carbon bond constructions via catalyzed cyanation/Brook rearrangement/C-acylation reactions of acylsilanes. Organic Letters. 4: 2957-60. PMID 12182598 DOI: 10.1021/ol0263649  1
2002 Zhao J, Yang J, Song R, Linghu X, Fan Q. The effect of annealing on the subsequent cold crystallization of amorphous poly(ethylene terephthalate) European Polymer Journal. 38: 645-648. DOI: 10.1016/S0014-3057(01)00238-5  1
2001 Zhao J, Song R, Zhang Z, Linghu X, Zheng Z, Fan Q. Study of the physical aging in semicrystalline poly(ethylene terephthalate) via differential scanning calorimetry Macromolecules. 34: 343-345. DOI: 10.1021/ma000796m  1
2001 Song R, Zhao J, Yang J, Linghu X, Fan Q. The study of stress-yielding of aged atactic polystyrene (a-PS) by differential scanning calorimetry Macromolecular Chemistry and Physics. 202: 512-515. DOI: 10.1002/1521-3935(20010201)202:4<512::AID-MACP512>3.0.CO;2-Q  1
2001 Zhao J, Song R, Zhang Z, Linghu X, Zheng Z, Fan Q. A study of the physical aging in semicrystalline poly(ethylene terephthalate) via differential scanning calorimetry Macromolecules. 34: 344-345.  1
2000 Song R, Linghu X, Fan Q. Observation of cohesional entanglement in physical-aged atactic polystyrene Journal of Materials Science Letters. 19: 385-387. DOI: 10.1023/A:1006778418928  1
2000 Linghu X, Zhao J, Song R, Fan QR. Relaxation of Chain Extension of Amorphous PET Fiber above the Glass Transition Temperature Chinese Chemical Letters. 11: 925-928.  1
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