| Year |
Citation |
Score |
| 2023 |
Cohen H, Wani NA, Ben Hur D, Migliolo L, Cardoso MH, Porat Z, Shimoni E, Franco OL, Shai Y. Interaction of Pexiganan (MSI-78)-Derived Analogues Reduces Inflammation and TLR4-Mediated Cytokine Secretion: A Comparative Study. Acs Omega. 8: 17856-17868. PMID 37251186 DOI: 10.1021/acsomega.3c00850 |
0.334 |
|
| 2022 |
Klug YA, Schwarzer R, Ravula T, Rotem E, Ramamoorthy A, Shai Y. Structural and Mechanistic Evidence for Calcium Interacting Sites in the HIV Transmembrane Protein gp41 Involved in Membrane Fusion. Biochemistry. PMID 35994087 DOI: 10.1021/acs.biochem.2c00372 |
0.351 |
|
| 2022 |
Ben Hur D, Kapach G, Wani NA, Kiper E, Ashkenazi M, Smollan G, Keller N, Efrati O, Shai Y. Antimicrobial Peptides against Multidrug-Resistant Biofilm from Cystic Fibrosis Patients. Journal of Medicinal Chemistry. PMID 35759644 DOI: 10.1021/acs.jmedchem.2c00270 |
0.302 |
|
| 2022 |
Wani NA, Stolovicki E, Hur DB, Shai Y. Site-Specific Isopeptide Bond Formation: A Powerful Tool for the Generation of Potent and Nontoxic Antimicrobial Peptides. Journal of Medicinal Chemistry. 65: 5085-5094. PMID 35290038 DOI: 10.1021/acs.jmedchem.2c00061 |
0.379 |
|
| 2021 |
Shprung T, Wani NA, Wilmes M, Mangoni ML, Bitler A, Shimoni E, Sahl HG, Shai Y. Opposing Effects of PhoPQ and PmrAB on the Properties of serovar Typhimurium: Implications on Resistance to Antimicrobial Peptides. Biochemistry. PMID 34547893 DOI: 10.1021/acs.biochem.1c00287 |
0.35 |
|
| 2021 |
Wani NA, Ben Hur D, Kapach G, Stolovicki E, Rotem E, Shai Y. Switching Bond: Generation of New Antimicrobial Peptides via the Incorporation of an Intramolecular Isopeptide Bond. Acs Infectious Diseases. PMID 34043312 DOI: 10.1021/acsinfecdis.1c00037 |
0.424 |
|
| 2020 |
Kapach G, Nuri R, Schmidt C, Danin A, Ferrera S, Savidor A, Gerlach RG, Shai Y. Loss of the Periplasmic Chaperone Skp and Mutations in the Efflux Pump AcrAB-TolC Play a Role in Acquired Resistance to Antimicrobial Peptides in . Frontiers in Microbiology. 11: 189. PMID 32210923 DOI: 10.3389/Fmicb.2020.00189 |
0.335 |
|
| 2019 |
Gross-Vered M, Shmuel-Galia L, Zarmi B, Humphries F, Thaiss C, Salame TM, David E, Chappell-Maor L, Fitzgerald KA, Shai Y, Jung S. TLR2 Dimerization Blockade Allows Generation of Homeostatic Intestinal Macrophages under Acute Colitis Challenge. Journal of Immunology (Baltimore, Md. : 1950). PMID 31882517 DOI: 10.4049/Jimmunol.1900470 |
0.383 |
|
| 2019 |
Klug YA, Schwarzer R, Rotem E, Charni M, Nudelman A, Gramatica A, Zarmi B, Rotter V, Shai Y. The HIV gp41 fusion protein inhibits T cell activation through the lentiviral lytic peptide 2 motif. Biochemistry. PMID 30602116 DOI: 10.1021/Acs.Biochem.8B01175 |
0.454 |
|
| 2018 |
Rotem E, Faingold O, Charni M, Klug YA, Harari D, Shmuel-Galia L, Nudelman A, Rotter V, Shai Y. The HTLV-1 gp21 fusion peptide inhibits antigen specific T-cell activation in-vitro and in mice. Plos Pathogens. 14: e1007044. PMID 29727445 DOI: 10.1371/Journal.Ppat.1007044 |
0.374 |
|
| 2018 |
Segev-Zarko LA, Kapach G, Josten M, Klug YA, Sahl HG, Shai Y. Deficient Lipid A Remodeling by the arnB Gene Promotes Biofilm Formation in Antimicrobial Peptide Susceptible Pseudomonas Aeruginosa. Biochemistry. PMID 29518324 DOI: 10.1021/Acs.Biochem.8B00149 |
0.412 |
|
| 2018 |
Klug YA, Ashkenazi A, Viard M, Porat Z, Blumenthal R, Shai Y. HIV GP41 Envelope Protein Early and Late Membrane Fusion Stages are Impaired by a Sphinganine Based Lipo-Peptide Biophysical Journal. 114: 458a. DOI: 10.1016/J.Bpj.2017.11.2531 |
0.489 |
|
| 2017 |
Shmuel-Galia L, Klug Y, Porat Z, Charni M, Zarmi B, Shai Y. Intramembrane attenuation of the TLR4-TLR6 dimer impairs receptor assembly and reduces microglia mediated neurodegeneration. The Journal of Biological Chemistry. PMID 28655763 DOI: 10.1074/Jbc.M117.784983 |
0.324 |
|
| 2017 |
Segev-Zarko LA, Shai Y. Methods for Investigating Biofilm Inhibition and Degradation by Antimicrobial Peptides. Methods in Molecular Biology (Clifton, N.J.). 1548: 309-322. PMID 28013514 DOI: 10.1007/978-1-4939-6737-7_22 |
0.441 |
|
| 2017 |
Kapach G, Klug YA, Rotem E, Dubreuil B, Shai Y. The HIV gp41 Conserved Pocket Binding Domain is Bifunctional, Alternatively Mediating both Immunosuppression and Membrane Fusion Biophysical Journal. 112: 532a. DOI: 10.1016/J.Bpj.2016.11.2879 |
0.411 |
|
| 2017 |
Segev-Zarko LT, Saar-Dover R, Brumfeld V, Luisa Mangoni M, Shai Y. Characterization of Anti-Biofilm Peptide Activity: A Biophysical Approach Biophysical Journal. 112: 23a. DOI: 10.1016/J.Bpj.2016.11.160 |
0.485 |
|
| 2016 |
Klug YA, Rotem E, Schwarzer R, Shai Y. Mapping out the intricate relationship of the HIV envelope protein and the membrane environment. Biochimica Et Biophysica Acta. PMID 27793589 DOI: 10.1016/J.Bbamem.2016.10.012 |
0.453 |
|
| 2016 |
Cappiello F, Di Grazia A, Li-Av SZ, Scali S, Ferrera L, Galietta L, Pini A, Shai Y, Di YP, Mangoni ML. Esculentin-1a-derived peptides promote clearance of P. aeruginosa internalized in cystic fibrosis bronchial cells as well as lung cells migration: Biochemical properties and a plausible mode of action. Antimicrobial Agents and Chemotherapy. PMID 27671059 DOI: 10.1128/Aac.00904-16 |
0.429 |
|
| 2016 |
Eckhard LH, Houri-Haddad Y, Sol A, Zeharia R, Shai Y, Beyth S, Domb AJ, Bachrach G, Beyth N. Sustained Release of Antibacterial Lipopeptides from Biodegradable Polymers against Oral Pathogens. Plos One. 11: e0162537. PMID 27606830 DOI: 10.1371/Journal.Pone.0162537 |
0.355 |
|
| 2016 |
Bublil EM, Cohen T, Arnusch CJ, Peleg A, Pines G, Lavi S, Yarden Y, Shai Y. Interfering with the Dimerization of the ErbB Receptors by Transmembrane Domain Derived Peptides Inhibits Tumorigenic Growth in Vitro and In Vivo. Biochemistry. PMID 27575020 DOI: 10.1021/Acs.Biochem.6B00450 |
0.377 |
|
| 2016 |
Rotem E, Reuven EM, Klug YA, Shai Y. The transmembrane domain of HIV-1 gp41 inhibits T-cell activation by targeting multiple TCR complex components through its GxxxG-motif. Biochemistry. PMID 26828096 DOI: 10.1021/Acs.Biochem.5B01307 |
0.41 |
|
| 2016 |
Klug YA, Kapach G, Rotem E, Dubreuil B, Shai Y. The HIV gp41 pocket binding domain enables C-terminal heptad repeat transition from mediating membrane fusion to immune modulation. The Biochemical Journal. PMID 26823547 DOI: 10.1042/Bj20151252 |
0.441 |
|
| 2016 |
Bitler A, Dover R, Shai Y. Anticancer Drug Colchicine Increases Disorder and Reduces Complexity in the Macrophage Membrane Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.507 |
0.337 |
|
| 2015 |
Ghosh A, Bera S, Shai Y, Mangoni ML, Bhunia A. NMR structure and binding of esculentin-1a (1-21)NH2 and its diastereomer to lipopolysaccharide: Correlation with biological functions. Biochimica Et Biophysica Acta. PMID 26724203 DOI: 10.1016/J.Bbamem.2015.12.027 |
0.486 |
|
| 2015 |
Sahl HG, Shai Y. Bacterial resistance to antimicrobial peptides. Biochimica Et Biophysica Acta. 1848: 3019-20. PMID 26342677 DOI: 10.1016/J.Bbamem.2015.08.009 |
0.448 |
|
| 2015 |
Di Grazia A, Cappiello F, Cohen H, Casciaro B, Luca V, Pini A, Di YP, Shai Y, Mangoni ML. D-Amino acids incorporation in the frog skin-derived peptide esculentin-1a(1-21)NH2 is beneficial for its multiple functions. Amino Acids. PMID 26162435 DOI: 10.1007/S00726-015-2041-Y |
0.461 |
|
| 2015 |
Nuri R, Shprung T, Shai Y. Defensive remodeling: How bacterial surface properties and biofilm formation promote resistance to antimicrobial peptides. Biochimica Et Biophysica Acta. PMID 26051126 DOI: 10.1016/J.Bbamem.2015.05.022 |
0.429 |
|
| 2015 |
Segev-Zarko L, Saar-Dover R, Brumfeld V, Mangoni ML, Shai Y. Mechanisms of biofilm inhibition and degradation by antimicrobial peptides. The Biochemical Journal. 468: 259-70. PMID 25761937 DOI: 10.1042/Bj20141251 |
0.438 |
|
| 2014 |
Eckhard LH, Sol A, Abtew E, Shai Y, Domb AJ, Bachrach G, Beyth N. Biohybrid polymer-antimicrobial peptide medium against Enterococcus faecalis. Plos One. 9: e109413. PMID 25279943 DOI: 10.1371/Journal.Pone.0109413 |
0.414 |
|
| 2014 |
Reuven EM, Ali M, Rotem E, Schwarzter R, Gramatica A, Futerman AH, Shai Y. The HIV-1 envelope transmembrane domain binds TLR2 through a distinct dimerization motif and inhibits TLR2-mediated responses. Plos Pathogens. 10: e1004248. PMID 25121610 DOI: 10.1371/Journal.Ppat.1004248 |
0.378 |
|
| 2014 |
Sal-Man N, Gerber D, Shai Y. Proline localized to the interaction interface can mediate self-association of transmembrane domains. Biochimica Et Biophysica Acta. 1838: 2313-8. PMID 24841754 DOI: 10.1016/J.Bbamem.2014.05.006 |
0.487 |
|
| 2014 |
Klug YA, Ashkenazi A, Viard M, Porat Z, Blumenthal R, Shai Y. Early and late HIV-1 membrane fusion events are impaired by sphinganine lipidated peptides that target the fusion site. The Biochemical Journal. 461: 213-22. PMID 24766462 DOI: 10.1042/Bj20140189 |
0.561 |
|
| 2014 |
Di Grazia A, Luca V, Segev-Zarko LA, Shai Y, Mangoni ML. Temporins A and B stimulate migration of HaCaT keratinocytes and kill intracellular Staphylococcus aureus. Antimicrobial Agents and Chemotherapy. 58: 2520-7. PMID 24514087 DOI: 10.1128/Aac.02801-13 |
0.38 |
|
| 2014 |
Reuven EM, Fink A, Shai Y. Regulation of innate immune responses by transmembrane interactions: lessons from the TLR family. Biochimica Et Biophysica Acta. 1838: 1586-93. PMID 24480409 DOI: 10.1016/J.Bbamem.2014.01.020 |
0.332 |
|
| 2013 |
Faingold O, Ashkenazi A, Kaushansky N, Ben-Nun A, Shai Y. An immunomodulating motif of the HIV-1 fusion protein is chirality-independent: implications for its mode of action. The Journal of Biological Chemistry. 288: 32852-60. PMID 24078631 DOI: 10.1074/Jbc.M113.512038 |
0.45 |
|
| 2013 |
Saar-Dover R, Ashkenazi A, Shai Y. Peptide interaction with and insertion into membranes. Methods in Molecular Biology (Clifton, N.J.). 1033: 173-83. PMID 23996178 DOI: 10.1007/978-1-62703-487-6_12 |
0.585 |
|
| 2013 |
Qiu J, Ashkenazi A, Liu S, Shai Y. Structural and functional properties of the membranotropic HIV-1 glycoprotein gp41 loop region are modulated by its intrinsic hydrophobic core. The Journal of Biological Chemistry. 288: 29143-50. PMID 23960077 DOI: 10.1074/Jbc.M113.496646 |
0.511 |
|
| 2013 |
Ott M, Shai Y, Haran G. Single-particle tracking reveals switching of the HIV fusion peptide between two diffusive modes in membranes. The Journal of Physical Chemistry. B. 117: 13308-21. PMID 23915358 DOI: 10.1021/Jp4039418 |
0.435 |
|
| 2013 |
Matalon E, Faingold O, Eisenstein M, Shai Y, Goldfarb D. The topology, in model membranes, of the core peptide derived from the T-cell receptor transmembrane domain. Chembiochem : a European Journal of Chemical Biology. 14: 1867-75. PMID 23881822 DOI: 10.1002/Cbic.201300191 |
0.544 |
|
| 2013 |
Ashkenazi A, Faingold O, Shai Y. HIV-1 fusion protein exerts complex immunosuppressive effects. Trends in Biochemical Sciences. 38: 345-9. PMID 23685134 DOI: 10.1016/J.Tibs.2013.04.003 |
0.374 |
|
| 2013 |
Fink A, Reuven EM, Arnusch CJ, Shmuel-Galia L, Antonovsky N, Shai Y. Assembly of the TLR2/6 transmembrane domains is essential for activation and is a target for prevention of sepsis. Journal of Immunology (Baltimore, Md. : 1950). 190: 6410-22. PMID 23677476 DOI: 10.4049/Jimmunol.1202033 |
0.397 |
|
| 2013 |
Ashkenazi A, Faingold O, Kaushansky N, Ben-Nun A, Shai Y. A highly conserved sequence associated with the HIV gp41 loop region is an immunomodulator of antigen-specific T cells in mice. Blood. 121: 2244-52. PMID 23325839 DOI: 10.1182/Blood-2012-11-468900 |
0.368 |
|
| 2013 |
Matalon E, Kaminker I, Zimmermann H, Eisenstein M, Shai Y, Goldfarb D. Topology of the trans-membrane peptide WALP23 in model membranes under negative mismatch conditions. The Journal of Physical Chemistry. B. 117: 2280-93. PMID 23311473 DOI: 10.1021/Jp310056H |
0.525 |
|
| 2013 |
Shai Y. ATR-FTIR studies in pore forming and membrane induced fusion peptides. Biochimica Et Biophysica Acta. 1828: 2306-13. PMID 23201348 DOI: 10.1016/J.Bbamem.2012.11.027 |
0.584 |
|
| 2013 |
Ashkenazi A, Shai Y. Viral Fusion Peptides Handbook of Biologically Active Peptides. 1904-1911. DOI: 10.1016/B978-0-12-385095-9.00260-8 |
0.412 |
|
| 2012 |
Saar-Dover R, Bitler A, Nezer R, Shmuel-Galia L, Firon A, Shimoni E, Trieu-Cuot P, Shai Y. D-alanylation of lipoteichoic acids confers resistance to cationic peptides in group B streptococcus by increasing the cell wall density. Plos Pathogens. 8: e1002891. PMID 22969424 DOI: 10.1371/Journal.Ppat.1002891 |
0.409 |
|
| 2012 |
Ulm H, Wilmes M, Shai Y, Sahl HG. Antimicrobial host defensins - specific antibiotic activities and innate defense modulation. Frontiers in Immunology. 3: 249. PMID 22912635 DOI: 10.3389/Fimmu.2012.00249 |
0.402 |
|
| 2012 |
Ashkenazi A, Merklinger E, Shai Y. Intramolecular interactions within the human immunodeficiency virus-1 gp41 loop region and their involvement in lipid merging. Biochemistry. 51: 6981-9. PMID 22894130 DOI: 10.1021/Bi300868F |
0.392 |
|
| 2012 |
Ashkenazi A, Viard M, Unger L, Blumenthal R, Shai Y. Sphingopeptides: dihydrosphingosine-based fusion inhibitors against wild-type and enfuvirtide-resistant HIV-1. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 4628-36. PMID 22872679 DOI: 10.1096/Fj.12-215111 |
0.473 |
|
| 2012 |
Faingold O, Cohen T, Shai Y. A GxxxG-like motif within HIV-1 fusion peptide is critical to its immunosuppressant activity, structure, and interaction with the transmembrane domain of the T-cell receptor. The Journal of Biological Chemistry. 287: 33503-11. PMID 22872636 DOI: 10.1074/Jbc.M112.370817 |
0.497 |
|
| 2012 |
Bitler A, Dover R, Shai Y. Fractal properties of macrophage membrane studied by AFM. Micron (Oxford, England : 1993). 43: 1239-45. PMID 22633851 DOI: 10.1016/J.Micron.2012.04.009 |
0.374 |
|
| 2012 |
Reuven EM, Dadon Y, Viard M, Manukovsky N, Blumenthal R, Shai Y. HIV-1 gp41 transmembrane domain interacts with the fusion peptide: implication in lipid mixing and inhibition of virus-cell fusion. Biochemistry. 51: 2867-78. PMID 22413880 DOI: 10.1021/Bi201721R |
0.53 |
|
| 2012 |
Arnusch CJ, Albada HB, van Vaardegem M, Liskamp RM, Sahl HG, Shadkchan Y, Osherov N, Shai Y. Trivalent ultrashort lipopeptides are potent pH dependent antifungal agents. Journal of Medicinal Chemistry. 55: 1296-302. PMID 22243686 DOI: 10.1021/Jm2014474 |
0.429 |
|
| 2012 |
Shprung T, Peleg A, Rosenfeld Y, Trieu-Cuot P, Shai Y. Effect of PhoP-PhoQ activation by broad repertoire of antimicrobial peptides on bacterial resistance. The Journal of Biological Chemistry. 287: 4544-51. PMID 22158870 DOI: 10.1074/Jbc.M111.278523 |
0.431 |
|
| 2012 |
Fink A, Sal-Man N, Gerber D, Shai Y. Transmembrane domains interactions within the membrane milieu: principles, advances and challenges. Biochimica Et Biophysica Acta. 1818: 974-83. PMID 22155642 DOI: 10.1016/J.Bbamem.2011.11.029 |
0.485 |
|
| 2012 |
Merklinger E, Gofman Y, Kedrov A, Driessen AJ, Ben-Tal N, Shai Y, Rapaport D. Membrane integration of a mitochondrial signal-anchored protein does not require additional proteinaceous factors. The Biochemical Journal. 442: 381-9. PMID 22142226 DOI: 10.1042/Bj20111363 |
0.479 |
|
| 2012 |
Gordon-Grossman M, Zimmermann H, Wolf SG, Shai Y, Goldfarb D. Investigation of model membrane disruption mechanism by melittin using pulse electron paramagnetic resonance spectroscopy and cryogenic transmission electron microscopy. The Journal of Physical Chemistry. B. 116: 179-88. PMID 22091896 DOI: 10.1021/Jp207159Z |
0.537 |
|
| 2012 |
Arnusch CJ, Ulm H, Josten M, Shadkchan Y, Osherov N, Sahl HG, Shai Y. Ultrashort peptide bioconjugates are exclusively antifungal agents and synergize with cyclodextrin and amphotericin B. Antimicrobial Agents and Chemotherapy. 56: 1-9. PMID 22006001 DOI: 10.1128/Aac.00468-11 |
0.492 |
|
| 2012 |
Shai Y, Fink A, Arnusch CJ, Shmuel-Galia L, Moshe Reuven E, Antonovsky N. Peptides Derived from the Transmembrane Domains of Toll-Like Receptors (TLR) 2/6 Interfere with Hetero-Associate with the TLRs and Inhibit their Activation Biophysical Journal. 102: 244a. DOI: 10.1016/J.Bpj.2011.11.1347 |
0.432 |
|
| 2011 |
Al-Benna S, Shai Y, Jacobsen F, Steinstraesser L. Oncolytic activities of host defense peptides. International Journal of Molecular Sciences. 12: 8027-51. PMID 22174648 DOI: 10.3390/Ijms12118027 |
0.364 |
|
| 2011 |
Ashkenazi A, Wexler-Cohen Y, Shai Y. Multifaceted action of Fuzeon as virus-cell membrane fusion inhibitor. Biochimica Et Biophysica Acta. 1808: 2352-8. PMID 21762676 DOI: 10.1016/J.Bbamem.2011.06.020 |
0.378 |
|
| 2011 |
Mangoni ML, Shai Y. Short native antimicrobial peptides and engineered ultrashort lipopeptides: similarities and differences in cell specificities and modes of action. Cellular and Molecular Life Sciences : Cmls. 68: 2267-80. PMID 21573781 DOI: 10.1007/S00018-011-0718-2 |
0.497 |
|
| 2011 |
Gordon-Grossman M, Kaminker I, Gofman Y, Shai Y, Goldfarb D. W-Band pulse EPR distance measurements in peptides using Gd(3+)-dipicolinic acid derivatives as spin labels. Physical Chemistry Chemical Physics : Pccp. 13: 10771-80. PMID 21552622 DOI: 10.1039/C1Cp00011J |
0.379 |
|
| 2011 |
Steinstraesser L, Hauk J, Schubert C, Al-Benna S, Stricker I, Hatt H, Shai Y, Steinau HU, Jacobsen F. Suppression of soft tissue sarcoma growth by a host defense-like lytic peptide. Plos One. 6: e18321. PMID 21483840 DOI: 10.1371/Journal.Pone.0018321 |
0.459 |
|
| 2011 |
Ashkenazi A, Viard M, Wexler-Cohen Y, Blumenthal R, Shai Y. Viral envelope protein folding and membrane hemifusion are enhanced by the conserved loop region of HIV-1 gp41. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2156-66. PMID 21429941 DOI: 10.1096/Fj.10-175752 |
0.413 |
|
| 2011 |
Ashkenazi A, Shai Y. Insights into the mechanism of HIV-1 envelope induced membrane fusion as revealed by its inhibitory peptides. European Biophysics Journal : Ebj. 40: 349-57. PMID 21258789 DOI: 10.1007/S00249-010-0666-Z |
0.558 |
|
| 2011 |
Steinstraesser L, Schubert C, Hauk J, Becerikli M, Stricker I, Koeller M, Hatt H, von Duering M, Shai Y, Steinau HU, Jacobsen F. Oncolytic designer host defense peptide suppresses growth of human liposarcoma. International Journal of Cancer. Journal International Du Cancer. 128: 2994-3004. PMID 20734391 DOI: 10.1002/Ijc.25627 |
0.343 |
|
| 2011 |
Shai Y, Cohen T, Cohen SJ, Antonovsky N, Cohen IR. A Similar Motif Shared by HIV-1 gp41 and TCRA Trans-Membrane Domains Exploited by the HIV Virus to Modulate T-Cell Proliferation Biophysical Journal. 100: 420a. DOI: 10.1016/J.Bpj.2010.12.2486 |
0.464 |
|
| 2010 |
Cohen T, Cohen SJ, Antonovsky N, Cohen IR, Shai Y. HIV-1 gp41 and TCRalpha trans-membrane domains share a motif exploited by the HIV virus to modulate T-cell proliferation. Plos Pathogens. 6: e1001085. PMID 20824090 DOI: 10.1371/Journal.Ppat.1001085 |
0.462 |
|
| 2010 |
Wexler-Cohen Y, Ashkenazi A, Viard M, Blumenthal R, Shai Y. Virus-cell and cell-cell fusion mediated by the HIV-1 envelope glycoprotein is inhibited by short gp41 N-terminal membrane-anchored peptides lacking the critical pocket domain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 4196-202. PMID 20605950 DOI: 10.1096/Fj.09-151704 |
0.491 |
|
| 2010 |
Bitler A, Lev N, Fridmann-Sirkis Y, Blank L, Cohen SR, Shai Y. Kinetics of interaction of HIV fusion protein (gp41) with lipid membranes studied by real-time AFM imaging. Ultramicroscopy. 110: 694-700. PMID 20399563 DOI: 10.1016/J.Ultramic.2010.02.034 |
0.428 |
|
| 2010 |
Epand RM, Epand RF, Arnusch CJ, Papahadjopoulos-Sternberg B, Wang G, Shai Y. Lipid clustering by three homologous arginine-rich antimicrobial peptides is insensitive to amino acid arrangement and induced secondary structure. Biochimica Et Biophysica Acta. 1798: 1272-80. PMID 20302840 DOI: 10.1016/J.Bbamem.2010.03.012 |
0.5 |
|
| 2010 |
Sackett K, Nethercott MJ, Epand RF, Epand RM, Kindra DR, Shai Y, Weliky DP. Comparative analysis of membrane-associated fusion peptide secondary structure and lipid mixing function of HIV gp41 constructs that model the early pre-hairpin intermediate and final hairpin conformations. Journal of Molecular Biology. 397: 301-15. PMID 20080102 DOI: 10.1016/J.Jmb.2010.01.018 |
0.51 |
|
| 2010 |
Rosenfeld Y, Lev N, Shai Y. Effect of the hydrophobicity to net positive charge ratio on antibacterial and anti-endotoxin activities of structurally similar antimicrobial peptides. Biochemistry. 49: 853-61. PMID 20058937 DOI: 10.1021/Bi900724X |
0.511 |
|
| 2010 |
Schubert C, Hauk J, Jacobsen F, Stricker I, Koeller M, Hatt H, Duering M, Shai Y, Steinau H, Steinstraesser L. 148B: Killing Mechanism Of Oncolytic Designer Host Defense Peptide - Necrosis Or Apoptosis? Plastic and Reconstructive Surgery. 125: 99. DOI: 10.1097/01.Prs.0000371882.41696.4D |
0.4 |
|
| 2010 |
Hauk J, Schubert C, Jacobsen F, Al-Benna S, Steinau H, Shai Y, Steinstraesser L. 147B: Host Defense-Like Lytic Peptide Suppresses Growth Of Human Synovial- And Fibrosarcoma Plastic and Reconstructive Surgery. 125: 98. DOI: 10.1097/01.Prs.0000371881.03578.6A |
0.406 |
|
| 2010 |
Rosenfeld Y, Lev N, Shai Y. A Comparative Study on the Effect of Hydrophobicity and Net Positive Charge on the Antibacterial and Anti- Endotoxin Activities of Antimicrobial Peptides Biophysical Journal. 98: 82a. DOI: 10.1016/J.Bpj.2009.12.464 |
0.496 |
|
| 2010 |
Ashkenazi A, Wexler-Cohen Y, Shai Y. A Short Lipopeptide Derived from the N-Heptad Repeat Region Inhibits HIV-1 Gp41 Mediated Fusion Via an Altered Mode of Action Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.3682 |
0.525 |
|
| 2010 |
Arnusch CJ, Albada HB, Liskamp RM, Shai Y. Nanostructure Determines Antifungal Activity of De Novo Designed pH Dependent Histidine Containing Ultra-Short Lipopeptides Biophysical Journal. 98: 278a-279a. DOI: 10.1016/J.Bpj.2009.12.1521 |
0.517 |
|
| 2010 |
Lohner K, Deutsch G, Sevcsik E, Zweytick D, Andrä J, Shai Y, Blondelle SE. N-Acylation of Antimicrobial Peptides Causes Different Mode of Cell Membrane Damage Biophysical Journal. 98: 218a. DOI: 10.1016/J.Bpj.2009.12.1176 |
0.598 |
|
| 2010 |
Epand RF, Epand RM, Arnusch CJ, Papahadjopoulos-Sternberg B, Wang G, Shai Y. Lipid Clustering by Three Homologous Arginine-Rich Antimicrobial Peptides is Insensitive to Amino Acid Arrangement Biophysical Journal. 98: 2-8. DOI: 10.1016/J.Bpj.2009.12.1175 |
0.539 |
|
| 2009 |
Gordon-Grossman M, Gofman Y, Zimmermann H, Frydman V, Shai Y, Ben-Tal N, Goldfarb D. A combined pulse EPR and Monte Carlo simulation study provides molecular insight on peptide-membrane interactions. The Journal of Physical Chemistry. B. 113: 12687-95. PMID 19725508 DOI: 10.1021/Jp905129B |
0.549 |
|
| 2009 |
Wexler-Cohen Y, Shai Y. Membrane-anchored HIV-1 N-heptad repeat peptides are highly potent cell fusion inhibitors via an altered mode of action. Plos Pathogens. 5: e1000509. PMID 19593361 DOI: 10.1371/Journal.Ppat.1000509 |
0.5 |
|
| 2009 |
Brotman Y, Makovitzki A, Shai Y, Chet I, Viterbo A. Synthetic ultrashort cationic lipopeptides induce systemic plant defense responses against bacterial and fungal pathogens. Applied and Environmental Microbiology. 75: 5373-9. PMID 19542326 DOI: 10.1128/Aem.00724-09 |
0.33 |
|
| 2009 |
Chen L, Merzlyakov M, Cohen T, Shai Y, Hristova K. Energetics of ErbB1 transmembrane domain dimerization in lipid bilayers. Biophysical Journal. 96: 4622-30. PMID 19486684 DOI: 10.1016/J.Bpj.2009.03.004 |
0.312 |
|
| 2009 |
Antcheva N, Morgera F, Creatti L, Vaccari L, Pag U, Pacor S, Shai Y, Sahl HG, Tossi A. Artificial beta-defensin based on a minimal defensin template. The Biochemical Journal. 421: 435-47. PMID 19453294 DOI: 10.1042/Bj20082242 |
0.331 |
|
| 2009 |
Mangoni ML, Shai Y. Temporins and their synergism against Gram-negative bacteria and in lipopolysaccharide detoxification. Biochimica Et Biophysica Acta. 1788: 1610-9. PMID 19422786 DOI: 10.1016/J.Bbamem.2009.04.021 |
0.433 |
|
| 2009 |
Makovitzki A, Fink A, Shai Y. Suppression of human solid tumor growth in mice by intratumor and systemic inoculation of histidine-rich and pH-dependent host defense-like lytic peptides. Cancer Research. 69: 3458-63. PMID 19351852 DOI: 10.1158/0008-5472.Can-08-3021 |
0.453 |
|
| 2009 |
Sackett K, Nethercott MJ, Shai Y, Weliky DP. Hairpin folding of HIV gp41 abrogates lipid mixing function at physiologic pH and inhibits lipid mixing by exposed gp41 constructs. Biochemistry. 48: 2714-22. PMID 19222185 DOI: 10.1021/Bi8019492 |
0.464 |
|
| 2009 |
Lev N, Fridmann-Sirkis Y, Blank L, Bitler A, Epand RF, Epand RM, Shai Y. Conformational stability and membrane interaction of the full-length ectodomain of HIV-1 gp41: implication for mode of action. Biochemistry. 48: 3166-75. PMID 19206186 DOI: 10.1021/Bi802243J |
0.524 |
|
| 2009 |
Klocek G, Schulthess T, Shai Y, Seelig J. Thermodynamics of melittin binding to lipid bilayers. Aggregation and pore formation. Biochemistry. 48: 2586-96. PMID 19173655 DOI: 10.1021/Bi802127H |
0.542 |
|
| 2009 |
Schubert C, Hauk J, Jacobsen F, Rittig A, Shai Y, Steinau H, Steinstraesser L. Op33: Host Defense-Like Lytic Peptide Suppresses Growth Of Human Liposarcoma Plastic and Reconstructive Surgery. 124: 690-691. DOI: 10.1097/01.Prs.0000358938.22030.89 |
0.423 |
|
| 2009 |
Peleg A, Rosenfeld Y, Shai Y. Biophysical Parameters Involved in Bacteria Resistance to Antimicrobial Peptides Biophysical Journal. 96: 154a. DOI: 10.1016/J.Bpj.2008.12.699 |
0.473 |
|
| 2009 |
Sackett K, Qiang W, Sun Y, Nethercott MJ, Shai Y, Weliky DP. Functional and Structural Measurements of HIV gp41 Fusion Protein Constructs Biophysical Journal. 96: 358a. DOI: 10.1016/J.Bpj.2008.12.1807 |
0.453 |
|
| 2008 |
Makovitzki A, Baram J, Shai Y. Antimicrobial lipopolypeptides composed of palmitoyl Di- and tricationic peptides: in vitro and in vivo activities, self-assembly to nanostructures, and a plausible mode of action. Biochemistry. 47: 10630-6. PMID 18783248 DOI: 10.1021/Bi8011675 |
0.535 |
|
| 2008 |
Vallon-Eberhard A, Makovitzki A, Beauvais A, Latgé JP, Jung S, Shai Y. Efficient clearance of Aspergillus fumigatus in murine lungs by an ultrashort antimicrobial lipopeptide, palmitoyl-lys-ala-DAla-lys. Antimicrobial Agents and Chemotherapy. 52: 3118-26. PMID 18606837 DOI: 10.1128/Aac.00526-08 |
0.399 |
|
| 2008 |
Mangoni ML, Epand RF, Rosenfeld Y, Peleg A, Barra D, Epand RM, Shai Y. Lipopolysaccharide, a key molecule involved in the synergism between temporins in inhibiting bacterial growth and in endotoxin neutralization. The Journal of Biological Chemistry. 283: 22907-17. PMID 18550541 DOI: 10.1074/Jbc.M800495200 |
0.35 |
|
| 2008 |
Rosenfeld Y, Sahl HG, Shai Y. Parameters involved in antimicrobial and endotoxin detoxification activities of antimicrobial peptides. Biochemistry. 47: 6468-78. PMID 18498177 DOI: 10.1021/Bi800450F |
0.465 |
|
| 2008 |
Cohen T, Pevsner-Fischer M, Cohen N, Cohen IR, Shai Y. Characterization of the interacting domain of the HIV-1 fusion peptide with the transmembrane domain of the T-cell receptor. Biochemistry. 47: 4826-33. PMID 18376816 DOI: 10.1021/Bi800100P |
0.532 |
|
| 2008 |
Pag U, Oedenkoven M, Sass V, Shai Y, Shamova O, Antcheva N, Tossi A, Sahl HG. Analysis of in vitro activities and modes of action of synthetic antimicrobial peptides derived from an alpha-helical 'sequence template'. The Journal of Antimicrobial Chemotherapy. 61: 341-52. PMID 18174202 DOI: 10.1093/Jac/Dkm479 |
0.493 |
|
| 2007 |
Quintana FJ, Gerber D, Bloch I, Cohen IR, Shai Y. Response to "Interaction between HIV gp41 fusion peptide and T cell receptor: putting the puzzle pieces back together". Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 1635. PMID 29430959 DOI: 10.1096/Fj.07-0604Ltr |
0.521 |
|
| 2007 |
Biggs JS, Rosenfeld Y, Shai Y, Olivera BM. Conolysin-Mt: a conus peptide that disrupts cellular membranes. Biochemistry. 46: 12586-93. PMID 17927208 DOI: 10.1021/Bi700775P |
0.569 |
|
| 2007 |
Lev N, Shai Y. Fatty acids can substitute the HIV fusion peptide in lipid merging and fusion: an analogy between viral and palmitoylated eukaryotic fusion proteins. Journal of Molecular Biology. 374: 220-30. PMID 17919659 DOI: 10.1016/J.Jmb.2007.09.008 |
0.602 |
|
| 2007 |
Makovitzki A, Viterbo A, Brotman Y, Chet I, Shai Y. Inhibition of fungal and bacterial plant pathogens in vitro and in planta with ultrashort cationic lipopeptides. Applied and Environmental Microbiology. 73: 6629-36. PMID 17720828 DOI: 10.1128/Aem.01334-07 |
0.322 |
|
| 2007 |
Wexler-Cohen Y, Shai Y. Demonstrating the C-terminal boundary of the HIV 1 fusion conformation in a dynamic ongoing fusion process and implication for fusion inhibition. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 3677-84. PMID 17575260 DOI: 10.1096/Fj.07-8582Com |
0.497 |
|
| 2007 |
Sal-Man N, Gerber D, Bloch I, Shai Y. Specificity in transmembrane helix-helix interactions mediated by aromatic residues. The Journal of Biological Chemistry. 282: 19753-61. PMID 17488729 DOI: 10.1074/Jbc.M610368200 |
0.352 |
|
| 2007 |
Lorin A, Charloteaux B, Fridmann-Sirkis Y, Thomas A, Shai Y, Brasseur R. Mode of membrane interaction and fusogenic properties of a de novo transmembrane model peptide depend on the length of the hydrophobic core. The Journal of Biological Chemistry. 282: 18388-96. PMID 17459883 DOI: 10.1074/Jbc.M700099200 |
0.603 |
|
| 2007 |
Quintana FJ, Gerber D, Bloch I, Cohen IR, Shai Y. A structurally altered D,L-amino acid TCRalpha transmembrane peptide interacts with the TCRalpha and inhibits T-cell activation in vitro and in an animal model. Biochemistry. 46: 2317-25. PMID 17288453 DOI: 10.1021/Bi061849G |
0.477 |
|
| 2007 |
Kristian SA, Timmer AM, Liu GY, Lauth X, Sal-Man N, Rosenfeld Y, Shai Y, Gallo RL, Nizet V. Impairment of innate immune killing mechanisms by bacteriostatic antibiotics. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 1107-16. PMID 17215486 DOI: 10.1096/Fj.06-6802Com |
0.309 |
|
| 2007 |
Bloch I, Quintana FJ, Gerber D, Cohen T, Cohen IR, Shai Y. T-cell inactivation and immunosuppressive activity induced by HIV gp41 via novel interacting motif. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 393-401. PMID 17185749 DOI: 10.1096/Fj.06-7061Com |
0.437 |
|
| 2007 |
Quintana FJ, Gerber D, Bloch I, Cohen IR, Shai Y. Response to "Interaction between HIV gp41 fusion peptide and T cell receptor: Putting the puzzle pieces back together" [2] Faseb Journal. 21: 1635. DOI: 10.1096/fj.07-0604ltr |
0.329 |
|
| 2006 |
Shai Y, Makovitzky A, Avrahami D. Host defense peptides and lipopeptides: modes of action and potential candidates for the treatment of bacterial and fungal infections. Current Protein & Peptide Science. 7: 479-86. PMID 17168781 DOI: 10.2174/138920306779025620 |
0.514 |
|
| 2006 |
Korazim O, Sackett K, Shai Y. Functional and structural characterization of HIV-1 gp41 ectodomain regions in phospholipid membranes suggests that the fusion-active conformation is extended. Journal of Molecular Biology. 364: 1103-17. PMID 17045292 DOI: 10.1016/J.Jmb.2006.08.091 |
0.592 |
|
| 2006 |
Makovitzki A, Avrahami D, Shai Y. Ultrashort antibacterial and antifungal lipopeptides. Proceedings of the National Academy of Sciences of the United States of America. 103: 15997-6002. PMID 17038500 DOI: 10.1073/Pnas.0606129103 |
0.513 |
|
| 2006 |
Rosenfeld Y, Barra D, Simmaco M, Shai Y, Mangoni ML. A synergism between temporins toward Gram-negative bacteria overcomes resistance imposed by the lipopolysaccharide protective layer. The Journal of Biological Chemistry. 281: 28565-74. PMID 16867990 DOI: 10.1074/Jbc.M606031200 |
0.442 |
|
| 2006 |
Rosenfeld Y, Shai Y. Lipopolysaccharide (Endotoxin)-host defense antibacterial peptides interactions: role in bacterial resistance and prevention of sepsis. Biochimica Et Biophysica Acta. 1758: 1513-22. PMID 16854372 DOI: 10.1016/J.Bbamem.2006.05.017 |
0.384 |
|
| 2006 |
Sackett K, Wexler-Cohen Y, Shai Y. Characterization of the HIV N-terminal fusion peptide-containing region in context of key gp41 fusion conformations. The Journal of Biological Chemistry. 281: 21755-62. PMID 16751188 DOI: 10.1074/Jbc.M603135200 |
0.41 |
|
| 2006 |
Papo N, Seger D, Makovitzki A, Kalchenko V, Eshhar Z, Degani H, Shai Y. Inhibition of tumor growth and elimination of multiple metastases in human prostate and breast xenografts by systemic inoculation of a host defense-like lytic peptide. Cancer Research. 66: 5371-8. PMID 16707464 DOI: 10.1158/0008-5472.Can-05-4569 |
0.353 |
|
| 2006 |
Mangoni ML, Papo N, Saugar JM, Barra D, Shai Y, Simmaco M, Rivas L. Effect of natural L- to D-amino acid conversion on the organization, membrane binding, and biological function of the antimicrobial peptides bombinins H. Biochemistry. 45: 4266-76. PMID 16566601 DOI: 10.1021/Bi052150Y |
0.472 |
|
| 2006 |
Wexler-Cohen Y, Johnson BT, Puri A, Blumenthal R, Shai Y. Structurally altered peptides reveal an important role for N-terminal heptad repeat binding and stability in the inhibitory action of HIV-1 peptide DP178. The Journal of Biological Chemistry. 281: 9005-10. PMID 16455666 DOI: 10.1074/Jbc.M512475200 |
0.539 |
|
| 2006 |
Rosenfeld Y, Papo N, Shai Y. Endotoxin (lipopolysaccharide) neutralization by innate immunity host-defense peptides. Peptide properties and plausible modes of action. The Journal of Biological Chemistry. 281: 1636-43. PMID 16293630 DOI: 10.1074/Jbc.M504327200 |
0.439 |
|
| 2006 |
Carmieli R, Papo N, Zimmermann H, Potapov A, Shai Y, Goldfarb D. Utilizing ESEEM spectroscopy to locate the position of specific regions of membrane-active peptides within model membranes. Biophysical Journal. 90: 492-505. PMID 16258052 DOI: 10.1529/Biophysj.105.062992 |
0.575 |
|
| 2006 |
Tomasinsig L, Skerlavaj B, Papo N, Giabbai B, Shai Y, Zanetti M. Mechanistic and functional studies of the interaction of a proline-rich antimicrobial peptide with mammalian cells. The Journal of Biological Chemistry. 281: 383-91. PMID 16257969 DOI: 10.1074/Jbc.M510354200 |
0.558 |
|
| 2006 |
Shai Y. Peptide-Lipid Interaction: Shedding Light into the Mode of Action and Cell Specificity of Antimicrobial Peptides Pli. 9: 177-201. DOI: 10.1007/3-540-28435-4_7 |
0.503 |
|
| 2006 |
Shai Y. Mechanism of Membrane Permeation and Pore Formation by Antimicrobial Peptides Protein-Lipid Interactions: From Membrane Domains to Cellular Networks. 187-217. DOI: 10.1002/3527606769.ch9 |
0.485 |
|
| 2005 |
Makovitzki A, Shai Y. pH-dependent antifungal lipopeptides and their plausible mode of action. Biochemistry. 44: 9775-84. PMID 16008362 DOI: 10.1021/Bi0502386 |
0.387 |
|
| 2005 |
Quintana FJ, Gerber D, Kent SC, Cohen IR, Shai Y. HIV-1 fusion peptide targets the TCR and inhibits antigen-specific T cell activation. The Journal of Clinical Investigation. 115: 2149-58. PMID 16007266 DOI: 10.1172/Jci23956 |
0.431 |
|
| 2005 |
Sackett K, Shai Y. The HIV fusion peptide adopts intermolecular parallel beta-sheet structure in membranes when stabilized by the adjacent N-terminal heptad repeat: a 13C FTIR study. Journal of Molecular Biology. 350: 790-805. PMID 15964015 DOI: 10.1016/J.Jmb.2005.05.030 |
0.472 |
|
| 2005 |
Sal-Man N, Gerber D, Shai Y. The identification of a minimal dimerization motif QXXS that enables homo- and hetero-association of transmembrane helices in vivo. The Journal of Biological Chemistry. 280: 27449-57. PMID 15911619 DOI: 10.1074/Jbc.M503095200 |
0.539 |
|
| 2005 |
Malina A, Shai Y. Conjugation of fatty acids with different lengths modulates the antibacterial and antifungal activity of a cationic biologically inactive peptide. The Biochemical Journal. 390: 695-702. PMID 15907192 DOI: 10.1042/Bj20050520 |
0.532 |
|
| 2005 |
Papo N, Shai Y. Host defense peptides as new weapons in cancer treatment. Cellular and Molecular Life Sciences : Cmls. 62: 784-90. PMID 15868403 DOI: 10.1007/S00018-005-4560-2 |
0.554 |
|
| 2005 |
Gerber D, Quintana FJ, Bloch I, Cohen IR, Shai Y. D-enantiomer peptide of the TCRalpha transmembrane domain inhibits T-cell activation in vitro and in vivo. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1190-2. PMID 15837719 DOI: 10.1096/Fj.04-3498Fje |
0.407 |
|
| 2005 |
Zelezetsky I, Pacor S, Pag U, Papo N, Shai Y, Sahl HG, Tossi A. Controlled alteration of the shape and conformational stability of alpha-helical cell-lytic peptides: effect on mode of action and cell specificity. The Biochemical Journal. 390: 177-88. PMID 15836439 DOI: 10.1042/Bj20042138 |
0.556 |
|
| 2005 |
Wexler-Cohen Y, Sackett K, Shai Y. The role of the N-terminal heptad repeat of HIV-1 in the actual lipid mixing step as revealed by its substitution with distant coiled coils. Biochemistry. 44: 5853-61. PMID 15823044 DOI: 10.1021/Bi047666G |
0.605 |
|
| 2005 |
Papo N, Shai Y. A molecular mechanism for lipopolysaccharide protection of Gram-negative bacteria from antimicrobial peptides. The Journal of Biological Chemistry. 280: 10378-87. PMID 15632151 DOI: 10.1074/Jbc.M412865200 |
0.515 |
|
| 2005 |
Sal-Man N, Shai Y. Arginine mutations within a transmembrane domain of Tar, an Escherichia coli aspartate receptor, can drive homodimer dissociation and heterodimer association in vivo. The Biochemical Journal. 385: 29-36. PMID 15330757 DOI: 10.1042/Bj20041022 |
0.384 |
|
| 2005 |
Sackett K, Shai Y. Erratum to “The HIV Fusion Peptide Adopts Intermolecular Parallel β-Sheet Structure in Membranes when Stabilized by the Adjacent N-Terminal Heptad Repeat: A 13C FTIR Study” [J. Mol. Biol. (2005) 350, 790–805] Journal of Molecular Biology. 351: 1169-1170. DOI: 10.1016/J.Jmb.2005.06.058 |
0.49 |
|
| 2004 |
Sal-Man N, Gerber D, Shai Y. Hetero-assembly between all-L- and all-D-amino acid transmembrane domains: forces involved and implication for inactivation of membrane proteins. Journal of Molecular Biology. 344: 855-64. PMID 15533450 DOI: 10.1016/J.Jmb.2004.09.066 |
0.556 |
|
| 2004 |
Gerber D, Pritsker M, Gunther-Ausborn S, Johnson B, Blumenthal R, Shai Y. Inhibition of HIV-1 envelope glycoprotein-mediated cell fusion by a DL-amino acid-containing fusion peptide: possible recognition of the fusion complex. The Journal of Biological Chemistry. 279: 48224-30. PMID 15339935 DOI: 10.1074/Jbc.M403436200 |
0.576 |
|
| 2004 |
Papo N, Braunstein A, Eshhar Z, Shai Y. Suppression of human prostate tumor growth in mice by a cytolytic D-, L-amino Acid Peptide: membrane lysis, increased necrosis, and inhibition of prostate-specific antigen secretion. Cancer Research. 64: 5779-86. PMID 15313920 DOI: 10.1158/0008-5472.Can-04-1438 |
0.463 |
|
| 2004 |
Braunstein A, Papo N, Shai Y. In vitro activity and potency of an intravenously injected antimicrobial peptide and its DL amino acid analog in mice infected with bacteria. Antimicrobial Agents and Chemotherapy. 48: 3127-9. PMID 15273131 DOI: 10.1128/Aac.48.8.3127-3129.2004 |
0.433 |
|
| 2004 |
Gallo SA, Sackett K, Rawat SS, Shai Y, Blumenthal R. The stability of the intact envelope glycoproteins is a major determinant of sensitivity of HIV/SIV to peptidic fusion inhibitors Journal of Molecular Biology. 340: 9-14. PMID 15184018 DOI: 10.1016/J.Jmb.2004.04.027 |
0.412 |
|
| 2004 |
Papo N, Shai Y. Effect of drastic sequence alteration and D-amino acid incorporation on the membrane binding behavior of lytic peptides Biochemistry. 43: 6393-6403. PMID 15157073 DOI: 10.1021/Bi049944H |
0.599 |
|
| 2004 |
Gerber D, Sal-Man N, Shai Y. Structural adaptation of the glycophorin A transmembrane homodimer to D-amino acid modifications Journal of Molecular Biology. 339: 243-250. PMID 15123435 DOI: 10.1016/J.Jmb.2004.03.004 |
0.481 |
|
| 2004 |
Gerber D, Sal-Man N, Shai Y. Two motifs within a transmembrane domain, one for homodimerization and the other for heterodimerization Journal of Biological Chemistry. 279: 21177-21182. PMID 14985340 DOI: 10.1074/Jbc.M400847200 |
0.501 |
|
| 2004 |
Shnaper S, Sackett K, Gallo SA, Blumenthal R, Shai Y. The C- and the N-terminal Regions of Glycoprotein 41 Ectodomain Fuse Membranes Enriched and Not Enriched with Cholesterol, Respectively Journal of Biological Chemistry. 279: 18526-18534. PMID 14981088 DOI: 10.1074/Jbc.M304950200 |
0.444 |
|
| 2004 |
Sal-Man N, Gerber D, Shai Y. The Composition Rather than Position of Polar Residues (QxxS) Drives Aspartate Receptor Transmembrane Domain Dimerization in Vivo Biochemistry. 43: 2309-2313. PMID 14979727 DOI: 10.1021/Bi0356294 |
0.381 |
|
| 2004 |
Pag U, Oedenkoven M, Papo N, Oren Z, Shai Y, Sahl HG. In vitro activity and mode of action of diastereomeric antimicrobial peptides against bacterial clinical isolates Journal of Antimicrobial Chemotherapy. 53: 230-239. PMID 14729742 DOI: 10.1093/Jac/Dkh083 |
0.434 |
|
| 2004 |
Avrahami D, Shai Y. A New Group of Antifungal and Antibacterial Lipopeptides Derived from Non-membrane Active Peptides Conjugated to Palmitic Acid Journal of Biological Chemistry. 279: 12277-12285. PMID 14709550 DOI: 10.1074/Jbc.M312260200 |
0.544 |
|
| 2003 |
Papo N, Shai Y. Can we predict biological activity of antimicrobial peptides from their interactions with model phospholipid membranes? Peptides. 24: 1693-1703. PMID 15019200 DOI: 10.1016/J.Peptides.2003.09.013 |
0.597 |
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| 2003 |
Avrahami D, Shai Y. Bestowing Antifungal and Antibacterial Activities by Lipophilic Acid Conjugation to D,L-Amino Acid-Containing Antimicrobial Peptides: A Plausible Mode of Action Biochemistry. 42: 14946-14956. PMID 14674771 DOI: 10.1021/Bi035142V |
0.528 |
|
| 2003 |
Mangoni ML, Papo N, Mignogna G, Andreu D, Shai Y, Barra D, Simmaco M. Ranacyclins, a New Family of Short Cyclic Antimicrobial Peptides: Biological Function, Mode of Action, and Parameters Involved in Target Specificity Biochemistry. 42: 14023-14035. PMID 14636071 DOI: 10.1021/Bi034521L |
0.582 |
|
| 2003 |
Peisajovich SG, Shai Y. Liposomes in Identification and Characterization of Viral Fusogenic Peptides Methods in Enzymology. 372: 361-373. PMID 14610824 DOI: 10.1016/S0076-6879(03)72021-7 |
0.561 |
|
| 2003 |
Sackett K, Shai Y. How structure correlates to function for membrane associated HIV-1 gp41 constructs corresponding to the N-terminal half of the ectodomain Journal of Molecular Biology. 333: 47-58. PMID 14516742 DOI: 10.1016/J.Jmb.2003.07.008 |
0.471 |
|
| 2003 |
Papo N, Shai Y. New lytic peptides based on the D,L-amphipathic helix motif preferentially kill tumor cells compared to normal cells Biochemistry. 42: 9346-9354. PMID 12899621 DOI: 10.1021/Bi027212O |
0.563 |
|
| 2003 |
Peisajovich SG, Shai Y. Viral fusion proteins: Multiple regions contribute to membrane fusion Biochimica Et Biophysica Acta - Biomembranes. 1614: 122-129. PMID 12873773 DOI: 10.1016/S0005-2736(03)00170-6 |
0.468 |
|
| 2003 |
Papo N, Shahar M, Eisenbach L, Shai Y. A novel lytic peptide composed of DL-amino acids selectively kills cancer cells in culture and in mice Journal of Biological Chemistry. 278: 21018-21023. PMID 12646578 DOI: 10.1074/Jbc.M211204200 |
0.485 |
|
| 2003 |
Peisajovich SG, Gallo SA, Blumenthal R, Shai Y. C-terminal octylation rescues an inactive T20 mutant. Implications for the mechanism of HIV/simian immunodeficiency virus-induced membrane fusion Journal of Biological Chemistry. 278: 21012-21017. PMID 12646555 DOI: 10.1074/Jbc.M212773200 |
0.52 |
|
| 2003 |
Peisajovich SG, Blank L, Epand RF, Epand RM, Shai Y. On the interaction between gp41 and membranes: The immunodominant loop stabilizes gp41 helical hairpin conformation Journal of Molecular Biology. 326: 1489-1501. PMID 12595260 DOI: 10.1016/S0022-2836(03)00040-8 |
0.525 |
|
| 2003 |
Papo N, Shai Y. Exploring peptide membrane interaction using surface plasmon resonance: Differentiation between pore formation versus membrane disruption by lytic peptides Biochemistry. 42: 458-466. PMID 12525173 DOI: 10.1021/Bi0267846 |
0.6 |
|
| 2002 |
Shai Y. Mode of action of membrane active antimicrobial peptides Biopolymers - Peptide Science Section. 66: 236-248. PMID 12491537 DOI: 10.1002/Bip.10260 |
0.572 |
|
| 2002 |
Sal-Man N, Oren Z, Shai Y. Preassembly of membrane-active peptides is an important factor in their selectivity toward target cells Biochemistry. 41: 11921-11930. PMID 12269837 DOI: 10.1021/Bi0260482 |
0.591 |
|
| 2002 |
Gerber D, Shai Y. Chirality-independent protein-protein recognition between transmembrane domains in vivo Journal of Molecular Biology. 322: 491-495. PMID 12225743 DOI: 10.1016/S0022-2836(02)00807-0 |
0.372 |
|
| 2002 |
Peisajovich SG, Epand RF, Epand RM, Shai Y. Sendai virus N-terminal fusion peptide consists of two similar repeats, both of which contribute to membrane fusion European Journal of Biochemistry. 269: 4342-4350. PMID 12199713 DOI: 10.1046/J.1432-1033.2002.03132.X |
0.531 |
|
| 2002 |
Oren Z, Ramesh J, Avrahami D, Suryaprakash N, Shai Y, Jelinek R. Structures and mode of membrane interaction of a short α helical lytic peptide and its diastereomer determined by NMR, FTIR, and fluorescence spectroscopy European Journal of Biochemistry. 269: 3869-3880. PMID 12180963 DOI: 10.1046/J.1432-1033.2002.03080.X |
0.601 |
|
| 2002 |
Papo N, Oren Z, Pag U, Sahl HG, Shai Y. The consequence of sequence alteration of an amphipathic alpha-helical antimicrobial peptide and its diastereomers. The Journal of Biological Chemistry. 277: 33913-21. PMID 12110678 DOI: 10.1074/Jbc.M204928200 |
0.544 |
|
| 2002 |
Shai Y. From innate immunity to de-novo designed antimicrobial peptides. Current Pharmaceutical Design. 8: 715-25. PMID 11945167 DOI: 10.2174/1381612023395367 |
0.568 |
|
| 2002 |
Peisajovich SG, Shai Y. New insights into the mechanism of virus-induced membrane fusion. Trends in Biochemical Sciences. 27: 183-90. PMID 11943545 DOI: 10.1016/S0968-0004(01)02050-3 |
0.488 |
|
| 2002 |
Sackett K, Shai Y. The HIV-1 gp41 N-terminal heptad repeat plays an essential role in membrane fusion. Biochemistry. 41: 4678-85. PMID 11926830 DOI: 10.1021/Bi0255322 |
0.6 |
|
| 2002 |
Peisajovich SG, Shai Y. High similarity between reverse-oriented sequences from HIV and foamy virus envelope glycoproteins. Aids Research and Human Retroviruses. 18: 309-12. PMID 11860678 DOI: 10.1089/088922202753472883 |
0.302 |
|
| 2002 |
Avrahami D, Shai Y. Conjugation of a magainin analogue with lipophilic acids controls hydrophobicity, solution assembly, and cell selectivity. Biochemistry. 41: 2254-63. PMID 11841217 DOI: 10.1021/Bi011549T |
0.512 |
|
| 2001 |
Avrahami D, Oren Z, Shai Y. Effect of multiple aliphatic amino acids substitutions on the structure, function, and mode of action of diastereomeric membrane active peptides. Biochemistry. 40: 12591-603. PMID 11601983 DOI: 10.1021/Bi0105330 |
0.602 |
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| 2001 |
Shai Y, Oren Z. From "carpet" mechanism to de-novo designed diastereomeric cell-selective antimicrobial peptides. Peptides. 22: 1629-41. PMID 11587791 DOI: 10.1016/S0196-9781(01)00498-3 |
0.581 |
|
| 2001 |
Peisajovich SG, Shai Y. SIV gp41 binds to membranes both in the monomeric and trimeric states: consequences for the neuropathology and inhibition of HIV infection. Journal of Molecular Biology. 311: 249-54. PMID 11478858 DOI: 10.1006/Jmbi.2001.4875 |
0.475 |
|
| 2001 |
Shai Y. Molecular recognition within the membrane milieu: implications for the structure and function of membrane Pproteins. The Journal of Membrane Biology. 182: 91-104. PMID 11447501 DOI: 10.1007/S00232-001-0034-A |
0.41 |
|
| 2001 |
Shai Y. Functional domains within fusion proteins: prospectives for development of peptide inhibitors of viral cell fusion. Bioscience Reports. 20: 535-55. PMID 11426693 DOI: 10.1023/A:1010411021326 |
0.544 |
|
| 2001 |
Gerber D, Shai Y. In vivo detection of hetero-association of glycophorin-A and its mutants within the membrane. The Journal of Biological Chemistry. 276: 31229-32. PMID 11402026 DOI: 10.1074/Jbc.M101889200 |
0.489 |
|
| 2001 |
Unger T, Oren Z, Shai Y. The effect of cyclization of magainin 2 and melittin analogues on structure, function, and model membrane interactions: implication to their mode of action. Biochemistry. 40: 6388-97. PMID 11371201 DOI: 10.1021/Bi0026066 |
0.612 |
|
| 2001 |
Samuel O, Shai Y. Participation of two fusion peptides in measles virus-induced membrane fusion: emerging similarity with other paramyxoviruses. Biochemistry. 40: 1340-9. PMID 11170461 DOI: 10.1021/Bi001533N |
0.593 |
|
| 2001 |
Aronson AI, Shai Y. Why Bacillus thuringiensis insecticidal toxins are so effective: Unique features of their mode of action Fems Microbiology Letters. 195: 1-8. PMID 11166987 DOI: 10.1111/J.1574-6968.2001.Tb10489.X |
0.355 |
|
| 2001 |
Kliger Y, Gallo SA, Peisajovich SG, Munoz-Barroso I, Avkin S, Blumenthal R, Shai Y. Mode of action of an antiviral peptide from HIV-1. Inhibition at a post-lipid mixing stage. The Journal of Biological Chemistry. 276: 1391-7. PMID 11027678 DOI: 10.1074/Jbc.M004113200 |
0.793 |
|
| 2000 |
Ghosh JK, Peisajovich SG, Shai Y. Sendai virus internal fusion peptide: structural and functional characterization and a plausible mode of viral entry inhibition. Biochemistry. 39: 11581-92. PMID 10995225 DOI: 10.1021/Bi0005963 |
0.56 |
|
| 2000 |
Kliger Y, Peisajovich SG, Blumenthal R, Shai Y. Membrane-induced conformational change during the activation of HIV-1 gp41. Journal of Molecular Biology. 301: 905-14. PMID 10966795 DOI: 10.1006/Jmbi.2000.4004 |
0.804 |
|
| 2000 |
Oren Z, Shai Y. Cyclization of a cytolytic amphipathic alpha-helical peptide and its diastereomer: effect on structure, interaction with model membranes, and biological function. Biochemistry. 39: 6103-14. PMID 10821683 DOI: 10.1021/Bi992408I |
0.586 |
|
| 2000 |
Gerber D, Shai Y. Insertion and organization within membranes of the delta-endotoxin pore-forming domain, helix 4-loop-helix 5, and inhibition of its activity by a mutant helix 4 peptide. The Journal of Biological Chemistry. 275: 23602-7. PMID 10811807 DOI: 10.1074/Jbc.M002596200 |
0.382 |
|
| 2000 |
Peisajovich SG, Samuel O, Shai Y. Paramyxovirus F1 protein has two fusion peptides: implications for the mechanism of membrane fusion. Journal of Molecular Biology. 296: 1353-65. PMID 10698638 DOI: 10.1006/Jmbi.2000.3543 |
0.564 |
|
| 2000 |
Peisajovich SG, Epand RF, Pritsker M, Shai Y, Epand RM. The polar region consecutive to the HIV fusion peptide participates in membrane fusion. Biochemistry. 39: 1826-33. PMID 10677233 DOI: 10.1021/Bi991887I |
0.588 |
|
| 2000 |
Hetru C, Letellier L, Oren Z, Hoffmann JA, Shai Y. Androctonin, a hydrophilic disulphide-bridged non-haemolytic anti-microbial peptide: a plausible mode of action. The Biochemical Journal. 345: 653-64. PMID 10642525 DOI: 10.1042/Bj3450653 |
0.576 |
|
| 2000 |
Kliger Y, Shai Y. Inhibition of HIV-1 entry before gp41 folds into its fusion-active conformation. Journal of Molecular Biology. 295: 163-8. PMID 10623516 DOI: 10.1006/Jmbi.1999.3368 |
0.784 |
|
| 2000 |
Hong J, Oren Z, Shai Y. Structure and organization of hemolytic and nonhemolytic diastereomers of antimicrobial peptides in membranes. Biochemistry. 38: 16963-73. PMID 10606532 DOI: 10.1021/Bi991850Y |
0.462 |
|
| 2000 |
Shai Y. Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by alpha-helical antimicrobial and cell non-selective membrane-lytic peptides. Biochimica Et Biophysica Acta. 1462: 55-70. PMID 10590302 DOI: 10.1016/S0005-2736(99)00200-X |
0.586 |
|
| 1999 |
Sharon M, Oren Z, Shai Y, Anglister J. 2D-NMR and ATR-FTIR study of the structure of a cell-selective diastereomer of melittin and its orientation in phospholipids. Biochemistry. 38: 15305-16. PMID 10563816 DOI: 10.1021/Bi991225T |
0.388 |
|
| 1999 |
Ghosh JK, Shai Y. Direct evidence that the N-terminal heptad repeat of Sendai virus fusion protein participates in membrane fusion. Journal of Molecular Biology. 292: 531-46. PMID 10497019 DOI: 10.1006/Jmbi.1999.3097 |
0.576 |
|
| 1999 |
Pritsker M, Rucker J, Hoffman TL, Doms RW, Shai Y. Effect of nonpolar substitutions of the conserved Phe11 in the fusion peptide of HIV-1 gp41 on its function, structure, and organization in membranes. Biochemistry. 38: 11359-71. PMID 10471286 DOI: 10.1021/Bi990232E |
0.612 |
|
| 1999 |
Oren Z, Shai Y. Mode of action of linear amphipathic alpha-helical antimicrobial peptides. Biopolymers. 47: 451-63. PMID 10333737 DOI: 10.1002/(Sici)1097-0282(1998)47:6<451::Aid-Bip4>3.0.Co;2-F |
0.546 |
|
| 1999 |
La Rocca P, Shai Y, Sansom MS. Peptide-bilayer interactions: simulations of dermaseptin B, an antimicrobial peptide. Biophysical Chemistry. 76: 145-59. PMID 10063609 DOI: 10.1016/S0301-4622(98)00232-4 |
0.561 |
|
| 1999 |
Oren Z, Hong J, Shai Y. A comparative study on the structure and function of a cytolytic alpha-helical peptide and its antimicrobial beta-sheet diastereomer. European Journal of Biochemistry. 259: 360-9. PMID 9914515 DOI: 10.1046/J.1432-1327.1999.00047.X |
0.566 |
|
| 1999 |
Ben-Efraim I, Kliger Y, Hermesh C, Shai Y. Membrane-induced step in the activation of Sendai virus fusion protein. Journal of Molecular Biology. 285: 609-25. PMID 9878433 DOI: 10.1006/Jmbi.1998.2370 |
0.819 |
|
| 1999 |
OREN Z, LERMAN JC, GUDMUNDSSON GH, AGERBERTH B, SHAI Y. Structure and organization of the human antimicrobial peptide LL-37 in phospholipid membranes: relevance to the molecular basis for its non-cell-selective activity Biochemical Journal. 341: 501-513. DOI: 10.1042/Bj3410501 |
0.575 |
|
| 1998 |
Gazit E, La Rocca P, Sansom MS, Shai Y. The structure and organization within the membrane of the helices composing the pore-forming domain of Bacillus thuringiensis delta-endotoxin are consistent with an "umbrella-like" structure of the pore. Proceedings of the National Academy of Sciences of the United States of America. 95: 12289-94. PMID 9770479 DOI: 10.1073/Pnas.95.21.12289 |
0.625 |
|
| 1998 |
Ghosh JK, Peisajovich SG, Ovadia M, Shai Y. Structure-function study of a heptad repeat positioned near the transmembrane domain of Sendai virus fusion protein which blocks virus-cell fusion. The Journal of Biological Chemistry. 273: 27182-90. PMID 9765238 DOI: 10.1074/Jbc.273.42.27182 |
0.485 |
|
| 1998 |
Pritsker M, Jones P, Blumenthal R, Shai Y. A synthetic all D-amino acid peptide corresponding to the N-terminal sequence of HIV-1 gp41 recognizes the wild-type fusion peptide in the membrane and inhibits HIV-1 envelope glycoprotein-mediated cell fusion. Proceedings of the National Academy of Sciences of the United States of America. 95: 7287-92. PMID 9636141 DOI: 10.1073/Pnas.95.13.7287 |
0.56 |
|
| 1998 |
Ghosh JK, Shai Y. A peptide derived from a conserved domain of Sendai virus fusion protein inhibits virus-cell fusion. A plausible mode of action. The Journal of Biological Chemistry. 273: 7252-9. PMID 9516418 DOI: 10.1074/Jbc.273.13.7252 |
0.562 |
|
| 1998 |
Durell SR, Martin I, Ruysschaert JM, Shai Y, Blumenthal R. What studies of fusion peptides tell us about viral envelope glycoprotein-mediated membrane fusion (review). Molecular Membrane Biology. 14: 97-112. PMID 9394290 DOI: 10.3109/09687689709048170 |
0.598 |
|
| 1997 |
Gazit E, Burshtein N, Ellar DJ, Sawyer T, Shai Y. Bacillus thuringiensis cytolytic toxin associates specifically with its synthetic helices A and C in the membrane bound state. Implications for the assembly of oligomeric transmembrane pores. Biochemistry. 36: 15546-54. PMID 9398283 DOI: 10.1021/Bi9707584 |
0.654 |
|
| 1997 |
Ghosh JK, Ovadia M, Shai Y. A leucine zipper motif in the ectodomain of Sendai virus fusion protein assembles in solution and in membranes and specifically binds biologically-active peptides and the virus. Biochemistry. 36: 15451-62. PMID 9398274 DOI: 10.1021/Bi971152I |
0.516 |
|
| 1997 |
Ghosh JK, Shaool D, Guillaud P, Cicéron L, Mazier D, Kustanovich I, Shai Y, Mor A. Selective cytotoxicity of dermaseptin S3 toward intraerythrocytic Plasmodium falciparum and the underlying molecular basis. The Journal of Biological Chemistry. 272: 31609-16. PMID 9395500 DOI: 10.1074/Jbc.272.50.31609 |
0.547 |
|
| 1997 |
Oren Z, Hong J, Shai Y. A repertoire of novel antibacterial diastereomeric peptides with selective cytolytic activity. The Journal of Biological Chemistry. 272: 14643-9. PMID 9169426 DOI: 10.1074/Jbc.272.23.14643 |
0.521 |
|
| 1997 |
Kliger Y, Aharoni A, Rapaport D, Jones P, Blumenthal R, Shai Y. Fusion peptides derived from the HIV type 1 glycoprotein 41 associate within phospholipid membranes and inhibit cell-cell Fusion. Structure-function study. The Journal of Biological Chemistry. 272: 13496-505. PMID 9153194 DOI: 10.1074/Jbc.272.21.13496 |
0.816 |
|
| 1997 |
Kliger Y, Shai Y. A leucine zipper-like sequence from the cytoplasmic tail of the HIV-1 envelope glycoprotein binds and perturbs lipid bilayers. Biochemistry. 36: 5157-69. PMID 9136877 DOI: 10.1021/Bi962935R |
0.82 |
|
| 1997 |
Oren Z, Shai Y. Selective lysis of bacteria but not mammalian cells by diastereomers of melittin: structure-function study. Biochemistry. 36: 1826-35. PMID 9048567 DOI: 10.1021/Bi962507L |
0.562 |
|
| 1997 |
Ben-Efraim I, Shai Y. The structure and organization of synthetic putative membranous segments of ROMK1 channel in phospholipid membranes. Biophysical Journal. 72: 85-96. PMID 8994595 DOI: 10.1016/S0006-3495(97)78649-1 |
0.459 |
|
| 1997 |
Ben-Efraim I, Shai Y. Secondary structure, membrane localization, and coassembly within phospholipid membranes of synthetic segments derived from the N- and C-termini regions of the ROMK1 K+ channel. Protein Science : a Publication of the Protein Society. 5: 2287-97. PMID 8931147 DOI: 10.1002/Pro.5560051115 |
0.423 |
|
| 1996 |
Rapaport D, Peled R, Nir S, Shai Y. Reversible surface aggregation in pore formation by pardaxin Biophysical Journal. 70: 2502-2512. PMID 8744290 DOI: 10.1016/S0006-3495(96)79822-3 |
0.521 |
|
| 1996 |
Peled-Zehavi H, Arkin IT, Engelman DM, Shai Y. Coassembly of synthetic segments of shaker K+ channel within phospholipid membranes. Biochemistry. 35: 6828-38. PMID 8639634 DOI: 10.1021/Bi952988T |
0.436 |
|
| 1996 |
Gazit E, Miller IR, Biggin PC, Sansom MS, Shai Y. Structure and orientation of the mammalian antibacterial peptide cecropin P1 within phospholipid membranes. Journal of Molecular Biology. 258: 860-70. PMID 8637016 DOI: 10.1006/Jmbi.1996.0293 |
0.674 |
|
| 1996 |
Shai Y, Oren Z. Diastereoisomers of cytolysins, a novel class of potent antibacterial peptides. The Journal of Biological Chemistry. 271: 7305-8. PMID 8631748 DOI: 10.1074/Jbc.271.13.7305 |
0.475 |
|
| 1996 |
Ben-Efraim I, Shai Y, Attali B. Cytoplasmic and extracellular IsK peptides activate endogenous K+ and Cl- channels in Xenopus oocytes. Evidence for regulatory function. The Journal of Biological Chemistry. 271: 8768-71. PMID 8621512 DOI: 10.1074/Jbc.271.15.8768 |
0.438 |
|
| 1996 |
Oren Z, Shai Y. A class of highly potent antibacterial peptides derived from pardaxin, a pore-forming peptide isolated from Moses sole fish Pardachirus marmoratus. European Journal of Biochemistry. 237: 303-10. PMID 8620888 DOI: 10.1111/J.1432-1033.1996.0303N.X |
0.541 |
|
| 1996 |
Vouldoukis I, Shai Y, Nicolas P, Mor A. Broad spectrum antibiotic activity of the skin-PYY. Febs Letters. 380: 237-40. PMID 8601432 DOI: 10.1016/0014-5793(96)00050-6 |
0.435 |
|
| 1996 |
Shai Y. Molecular recognition between membrane-spanning polypeptides. Trends in Biochemical Sciences. 20: 460-4. PMID 8578589 DOI: 10.1016/S0968-0004(00)89101-X |
0.42 |
|
| 1995 |
Gazit E, Shai Y. The assembly and organization of the alpha 5 and alpha 7 helices from the pore-forming domain of Bacillus thuringiensis delta-endotoxin. Relevance to a functional model. The Journal of Biological Chemistry. 270: 2571-8. PMID 7852320 DOI: 10.1074/Jbc.270.6.2571 |
0.532 |
|
| 1995 |
Pouny Y, Shai Y. Synthetic peptides corresponding to the four P regions of Electrophorus electricus Na+ channel: interaction with and organization in model phospholipid membranes. Biochemistry. 34: 7712-21. PMID 7779818 DOI: 10.1021/Bi00023A018 |
0.465 |
|
| 1995 |
Epand RM, Shai Y, Segrest JP, Anantharamaiah GM. Mechanisms for the modulation of membrane bilayer properties by amphipathic helical peptides. Biopolymers. 37: 319-38. PMID 7632881 DOI: 10.1002/Bip.360370504 |
0.571 |
|
| 1995 |
Gazit E, Boman A, Boman HG, Shai Y. Interaction of the mammalian antibacterial peptide cecropin P1 with phospholipid vesicles. Biochemistry. 34: 11479-88. PMID 7547876 DOI: 10.1021/Bi00036A021 |
0.679 |
|
| 1995 |
Gazit E, Shai Y. Self- and co-assembly of helical segments from the pore-forming domain of Bacillus thuringiensis CryIIIA δ-endotoxin Toxicon. 33: 272. DOI: 10.1016/0041-0101(95)99275-8 |
0.409 |
|
| 1995 |
Shai Y, Rapaport D, Gazit E, Pouny Y, Strahilevitz J, Oren Z. Molecular mechanism of membrane permeation by cytolytic toxins Toxicon. 33: 272. DOI: 10.1016/0041-0101(95)99274-7 |
0.494 |
|
| 1995 |
Rapaport D, Ovadia M, Shai Y. A synthetic peptide corresponding to a conserved heptad repeat domain is a potent inhibitor of Sendai virus-cell fusion: an emerging similarity with functional domains of other viruses. The Embo Journal. 14: 5524-5531. DOI: 10.1002/J.1460-2075.1995.Tb00239.X |
0.548 |
|
| 1994 |
Ben-Efraim I, Strahilevitz J, Bach D, Shai Y. Secondary structure and membrane localization of synthetic segments and a truncated form of the IsK (minK) protein. Biochemistry. 33: 6966-73. PMID 8204631 DOI: 10.1021/Bi00188A028 |
0.458 |
|
| 1994 |
Shai Y. Pardaxin: channel formation by a shark repellant peptide from fish. Toxicology. 87: 109-29. PMID 8160183 DOI: 10.1016/0300-483X(94)90157-0 |
0.441 |
|
| 1994 |
Strahilevitz J, Mor A, Nicolas P, Shai Y. Spectrum of antimicrobial activity and assembly of dermaseptin-b and its precursor form in phospholipid membranes. Biochemistry. 33: 10951-60. PMID 8086412 DOI: 10.1021/Bi00202A014 |
0.493 |
|
| 1994 |
Gazit E, Lee WJ, Brey PT, Shai Y. Mode of action of the antibacterial cecropin B2: a spectrofluorometric study. Biochemistry. 33: 10681-92. PMID 8075068 DOI: 10.1021/Bi00201A016 |
0.699 |
|
| 1994 |
Peled H, Shai Y. Synthetic S-2 and H-5 segments of the Shaker K+ channel: secondary structure, membrane interaction, and assembly within phospholipid membranes. Biochemistry. 33: 7211-9. PMID 8003486 DOI: 10.1021/Bi00189A025 |
0.448 |
|
| 1994 |
Rapaport D, Nir S, Shai Y. Capacities of pardaxin analogues to induce fusion and leakage of negatively charged phospholipid vesicles are not necessarily correlated. Biochemistry. 33: 12615-24. PMID 7918487 DOI: 10.1021/Bi00208A012 |
0.548 |
|
| 1994 |
Gazit E, Bach D, Kerr ID, Sansom MS, Chejanovsky N, Shai Y. The alpha-5 segment of Bacillus thuringiensis delta-endotoxin: in vitro activity, ion channel formation and molecular modelling. The Biochemical Journal. 304: 895-902. PMID 7529493 DOI: 10.1042/Bj3040895 |
0.606 |
|
| 1993 |
Rapaport D, Hague GR, Pouny Y, Shai Y. pH- and ionic strength-dependent fusion of phospholipid vesicles induced by pardaxin analogues or by mixtures of charge-reversed peptides. Biochemistry. 32: 3291-7. PMID 8461295 DOI: 10.1021/Bi00064A011 |
0.463 |
|
| 1993 |
Ben-Efraim I, Bach D, Shai Y. Spectroscopic and functional characterization of the putative transmembrane segment of the minK potassium channel. Biochemistry. 32: 2371-7. PMID 8443177 DOI: 10.1021/Bi00060A031 |
0.416 |
|
| 1993 |
Eshel Y, Shai Y, Vorherr T, Carafoli E, Salomon Y. Synthetic peptides corresponding to the calmodulin-binding domains of skeletal muscle myosin light chain kinase and human erythrocyte Ca2+ pump interact with and permeabilize liposomes and cell membranes. Biochemistry. 32: 6721-8. PMID 8392369 DOI: 10.1021/Bi00077A027 |
0.496 |
|
| 1993 |
Gazit E, Shai Y. Structural and functional characterization of the alpha 5 segment of Bacillus thuringiensis delta-endotoxin. Biochemistry. 32: 3429-36. PMID 8384882 DOI: 10.1021/Bi00064A029 |
0.549 |
|
| 1993 |
Peled H, Shai Y. Membrane interaction and self-assembly within phospholipid membranes of synthetic segments corresponding to the H-5 region of the shaker K+ channel. Biochemistry. 32: 7879-85. PMID 8347593 DOI: 10.1021/Bi00082A007 |
0.507 |
|
| 1993 |
Gazit E, Shai Y. Structural characterization, membrane interaction, and specific assembly within phospholipid membranes of hydrophobic segments from Bacillus thuringiensis var. israelensis cytolytic toxin. Biochemistry. 32: 12363-71. PMID 8241124 DOI: 10.1021/Bi00097A013 |
0.711 |
|
| 1993 |
Pouny Y, Rapaport D, Mor A, Nicolas P, Shai Y. Interaction of antimicrobial dermaseptin and its fluorescently labeled analogues with phospholipid membranes. Biochemistry. 31: 12416-23. PMID 1463728 DOI: 10.1021/Bi00164A017 |
0.491 |
|
| 1992 |
Pouny Y, Shai Y. Interaction of D-amino acid incorporated analogues of pardaxin with membranes. Biochemistry. 31: 9482-90. PMID 1390731 DOI: 10.1021/Bi00154A022 |
0.54 |
|
| 1992 |
Rapaport D, Danin M, Gazit E, Shai Y. Membrane interactions of the sodium channel S4 segment and its fluorescently-labeled analogues. Biochemistry. 31: 8868-75. PMID 1327106 DOI: 10.1021/Bi00152A025 |
0.655 |
|
| 1990 |
Jacobson KA, Eastman RC, Carson RE, Channing MA, Dunn BB, Lesniak MA, Taylor KE, Kirk KL, Herscovitch P, Roth J, Shai Y. Positron emission tomographic (PET) imaging of a peptide receptor in vivo using a general prosthetic group methodology: 18F-labeled insulin European Journal of Pharmacology. 183: 1117-1118. DOI: 10.1016/0014-2999(90)92986-S |
0.456 |
|
| 1989 |
Shai Y, Kirk KL, Channing MA, Dunn BB, Lesniak MA, Eastman RC, Finn RD, Roth J, Jacobson KA. 18F-labeled insulin: A prosthetic group methodology for incorporation of a positron emitter into peptides and proteins Biochemistry. 28: 4801-4806. PMID 2669963 DOI: 10.1021/Bi00437A042 |
0.443 |
|
| 1989 |
Shai Y, Brunck TK, Chaiken IM. Antisense peptide recognition of sense peptides: sequence simplification and evaluation of forces underlying the interaction. Biochemistry. 28: 8804-11. PMID 2605221 DOI: 10.1021/Bi00448A019 |
0.682 |
|
| 1988 |
Chaiken IM, Shai Y, Fassina G, Caliceti P. Current development of analytical affinity chromatography: Design and biotechnological uses of molecular recognition surfaces Makromolekulare Chemie. Macromolecular Symposia. 17: 269-279. DOI: 10.1002/Masy.19880170119 |
0.615 |
|
| 1987 |
Shai Y, Flashner M, Chaiken IM. Anti-sense peptide recognition of sense peptides: direct quantitative characterization with the ribonuclease S-peptide system using analytical high-performance affinity chromatography. Biochemistry. 26: 669-75. PMID 3567139 DOI: 10.1021/Bi00377A002 |
0.671 |
|
| 1986 |
PATCHORNIK A, NOV E, JACOBSON KA, SHAI Y. ChemInform Abstract: Polymeric Transfer Reagents for Organic Synthesis with Self-Control toward Automation in Organic Synthesis Chemischer Informationsdienst. 17. DOI: 10.1002/Chin.198648389 |
0.584 |
|
| 1985 |
Shai Y, Jacobson KA, Patchornik A. "Mediator methodology" for the synthesis of peptides in a two-polymeric system Journal of the American Chemical Society. 107: 4249-4252. DOI: 10.1021/Ja00300A029 |
0.652 |
|
| 1985 |
SHAI Y, JACOBSON KA, PATCHORNIK A. ChemInform Abstract: “MEDIATOR METHODOLOGY” FOR THE SYNTHESIS OF PEPTIDES IN A TWO-POLYMERIC SYSTEM Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198544300 |
0.708 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2016 |
Pan XY, Zhao W, Wang CY, Lin J, Zeng XY, Ren RX, Wang K, Xun TR, Shai Y, Liu SW. Heat shock protein 90 facilitates latent HIV reactivation through maintaining the function of positive transcriptional elongation factor b (p-TEFb) under proteasome inhibition. The Journal of Biological Chemistry. PMID 27799305 DOI: 10.1074/Jbc.M116.743906 |
0.296 |
|
| 2016 |
Shmuel-Galia L, Aychek T, Fink A, Porat Z, Zarmi B, Bernshtein B, Brenner O, Jung S, Shai Y. Neutralization of pro-inflammatory monocytes by targeting TLR2 dimerization ameliorates colitis. The Embo Journal. PMID 26884587 DOI: 10.15252/Embj.201592649 |
0.287 |
|
| 2019 |
Sperber HS, Welke RW, Petazzi RA, Bergmann R, Schade M, Shai Y, Chiantia S, Herrmann A, Schwarzer R. Self-association and subcellular localization of Puumala hantavirus envelope proteins. Scientific Reports. 9: 707. PMID 30679542 DOI: 10.1038/S41598-018-36879-Y |
0.283 |
|
| 2011 |
Papasergi S, Brega S, Mistou MY, Firon A, Oxaran V, Dover R, Teti G, Shai Y, Trieu-Cuot P, Dramsi S. The GBS PI-2a pilus is required for virulence in mice neonates. Plos One. 6: e18747. PMID 21525979 DOI: 10.1371/Journal.Pone.0018747 |
0.282 |
|
| 2015 |
Saar Dover R, Bitler A, Shimoni E, Trieu-Cuot P, Shai Y. Multiparametric AFM reveals turgor-responsive net-like peptidoglycan architecture in live streptococci. Nature Communications. 6: 7193. PMID 26018339 DOI: 10.1038/Ncomms8193 |
0.279 |
|
| 2012 |
Saar-Dover R, Bitler A, Nezer R, Shmuel-Galia L, Firon A, Shimoni E, Trieu-Cuot P, Shai Y. Correction: D-Alanylation of Lipoteichoic Acids Confers Resistance to Cationic Peptides in Group B Streptococcus by Increasing the Cell Wall Density Plos Pathogens. 8. DOI: 10.1371/annotation/05894f00-6d95-4b7a-aff1-2e008d2a864f |
0.275 |
|
| 1989 |
Shai Y, Fox J, Caratsch C, Shih YL, Edwards C, Lazarovici P. Sequencing and synthesis of pardaxin, a polypeptide from the Red Sea Moses sole with ionophore activity. Febs Letters. 242: 161-6. PMID 2462511 DOI: 10.1016/0014-5793(88)81007-X |
0.268 |
|
| 2000 |
Peri I, Mamrud-Brains H, Rodin S, Krizhanovsky V, Shai Y, Nir S, Naim M. Rapid entry of bitter and sweet tastants into liposomes and taste cells: implications for signal transduction. American Journal of Physiology-Cell Physiology. 278. PMID 10644507 DOI: 10.1152/Ajpcell.2000.278.1.C17 |
0.265 |
|
| 2017 |
Bitler A, Dover RS, Shai Y. Fractal properties of cell surface structures: A view from AFM. Seminars in Cell & Developmental Biology. PMID 28760392 DOI: 10.1016/J.Semcdb.2017.07.034 |
0.252 |
|
| 2009 |
Shai Y. Kinetics and thermodynamics of the microgene polymerization reaction. Biophysical Journal. 96: 1673-4. PMID 19254529 DOI: 10.1016/J.Bpj.2008.11.010 |
0.249 |
|
| 2013 |
Saar-Dover R, Shai Y. CAMP-Membrane Interactions Using Fluorescence Spectroscopy Bio-Protocol. 3. DOI: 10.21769/bioprotoc.846 |
0.247 |
|
| 2007 |
Huberman L, Gollop N, Mumcuoglu KY, Breuer E, Bhusare SR, Shai Y, Galun R. Antibacterial substances of low molecular weight isolated from the blowfly, Lucilia sericata. Medical and Veterinary Entomology. 21: 127-31. PMID 17550431 DOI: 10.1111/J.1365-2915.2007.00668.X |
0.232 |
|
| 2010 |
Kumar TA, Bardea A, Shai Y, Yoffe A, Naaman R. Patterning gradient properties from sub-micrometers to millimeters by magnetolithography. Nano Letters. 10: 2262-7. PMID 20491500 DOI: 10.1021/Nl1013635 |
0.229 |
|
| 1994 |
Vago R, Shai Y, Ben-Zion M, Duhinsky Z, Achituv Y. Computerized tomography and image analysis: A tool for examining the skeletal characteristics of reef‐building organisms Limnology and Oceanography. 39: 448-452. DOI: 10.4319/Lo.1994.39.2.0448 |
0.197 |
|
| 2021 |
Frenkel N, Saar Dover R, Titon E, Shai Y, Rom-Kedar V. Bistable Bacterial Growth Dynamics in the Presence of Antimicrobial Agents. Antibiotics (Basel, Switzerland). 10. PMID 33477524 DOI: 10.3390/antibiotics10010087 |
0.176 |
|
| 1993 |
Shai Y, Doll L, Miller I. Ion release from vesicles induced by pardaxin and its analogues Bioelectrochemistry and Bioenergetics. 29: 315-326. DOI: 10.1016/0302-4598(93)85006-F |
0.066 |
|
| 2008 |
Chou LC, Jang CY, Wu YH, Tsai WC, Wang SK, Chen J, Chang SC, Liu CC, Shai Y, Wen CR. Photon-exposure-dependent photon-stimulated desorption for obtaining photolysis cross section of molecules adsorbed on surface by monochromatic soft x-ray photons. The Journal of Chemical Physics. 129: 214104. PMID 19063541 DOI: 10.1063/1.3026598 |
0.058 |
|
| 1985 |
Shai Y, Warshawsky A. Stability Constants of Oximes of 4-Substituted-2-acetylphenols [1] Israel Journal of Chemistry. 25: 233-235. DOI: 10.1002/ijch.198500036 |
0.054 |
|
| 2007 |
Wen CR, Jang CY, Chou LC, Chen J, Wu YH, Chang SC, Tsai WC, Liu CC, Wang SK, Shai Y. Soft x-ray photoreactions of CF3Cl adsorbed on Si(111)-7x7 studied by continuous-time photon-stimulated desorption spectroscopy near F(1s) edge. The Journal of Chemical Physics. 127: 114704. PMID 17887867 DOI: 10.1063/1.2772257 |
0.048 |
|
| 2006 |
Liu S, Ma L, Huang W, Shai Y, Ji X, Ding L, Liu Y, Yu L, Zhao S. Decreased expression of the human carbonyl reductase 2 gene HCR2 in hepatocellular carcinoma. Cellular & Molecular Biology Letters. 11: 230-41. PMID 16847567 DOI: 10.2478/s11658-006-0022-6 |
0.038 |
|
| 2015 |
Shai Y, Ingman D, Suhir E. Modified dynamic reliability model for damage accumulation Ieee Aerospace Conference Proceedings. 2015. DOI: 10.1109/AERO.2015.7118914 |
0.034 |
|
| 1984 |
Eliachar I, Marcovich A, Shai YH. Rotary-door flap in laryngotracheal reconstruction. Archives of Otolaryngology (Chicago, Ill. : 1960). 110: 585-90. PMID 6477276 DOI: 10.1001/archotol.1984.00800350027008 |
0.02 |
|
| 2003 |
Shai Y. Biochimica et biophysica acta - Biomembranes: Preface Biochimica Et Biophysica Acta - Biomembranes. 1614: 1-2. DOI: 10.1016/S0005-2736(03)00157-3 |
0.016 |
|
| 2009 |
Shai Y, Kollender R. Women and music in Jewish society: Woman's role in the music tradition in Israel Jewish Women in Pre-State Israel: Life History, Politics, and Culture. 277-282. |
0.011 |
|
| 2013 |
Shai Y, Ingman D, Suhir E. Reliability of objects in aerospace technologies and beyond: Holistic risk management approach Ieee Aerospace Conference Proceedings. DOI: 10.1109/AERO.2013.6496832 |
0.01 |
|
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