cached image

Irwin M. Chaiken - Publications

Biochemistry Drexel University College of Medicine, Philadelphia, PA, United States 
protein recognition, protein machine that controls HIV-1 cell entry into host cells

144 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Cusimano GM, Gary EN, Bell MR, Warner BM, Connors J, Tursi NJ, Ali AR, Zhang S, Canziani G, Taramangalam B, Gordon EA, Chaiken IM, Wootton SK, Smith T, Ramos S, et al. Improved Durability to SARS-CoV-2 Vaccine Immunity following Coimmunization with Molecular Adjuvant Adenosine Deaminase-1. Journal of Immunology (Baltimore, Md. : 1950). 209: 118-127. PMID 35750334 DOI: 10.4049/jimmunol.2200056  0.441
2021 Zhang S, Holmes AP, Dick A, Rashad AA, Enríquez Rodríguez L, Canziani GA, Root MJ, Chaiken IM. Altered Env conformational dynamics as a mechanism of resistance to peptide-triazole HIV-1 inactivators. Retrovirology. 18: 31. PMID 34627310 DOI: 10.1186/s12977-021-00575-z  0.565
2021 Ang CG, Carter E, Haftl A, Zhang S, Rashad AA, Kutzler M, Abrams CF, Chaiken IM. Peptide Triazole Thiol Irreversibly Inactivates Metastable HIV-1 Env by Accessing Conformational Triggers Intrinsic to Virus-Cell Entry. Microorganisms. 9. PMID 34204725 DOI: 10.3390/microorganisms9061286  0.549
2021 Gaffney A, Nangarlia A, Ang CG, Gossert S, Rashad Ahmed AA, Hossain MA, Abrams CF, Smith AB, Chaiken I. HIV-1 Env-Dependent Cell Killing by Bifunctional Small-Molecule/Peptide Conjugates. Acs Chemical Biology. PMID 33410670 DOI: 10.1021/acschembio.0c00888  0.393
2020 Parajuli B, Acharya K, Nangarlia A, Zhang S, Parajuli B, Dick A, Ngo B, Abrams CF, Chaiken I. Identification of a glycan cluster in gp120 essential for irreversible HIV-1 lytic inactivation by a lectin-based recombinantly engineered protein conjugate. The Biochemical Journal. PMID 33057580 DOI: 10.1042/BCJ20200495  0.599
2020 Gossert ST, Parajuli B, Chaiken I, Abrams CF. Roles of Variable Linker Length in Dual Acting Virucidal Entry Inhibitors on HIV-1 Potency via On-the-fly Free Energy Molecular Simulations. Protein Science : a Publication of the Protein Society. PMID 32926485 DOI: 10.1002/Pro.3949  0.415
2020 Prévost J, Tolbert WD, Medjahed H, Sherburn RT, Madani N, Zoubchenok D, Gendron-Lepage G, Gaffney AE, Grenier MC, Kirk S, Vergara N, Han C, Mann BT, Chénine AL, Ahmed A, ... Chaiken I, et al. The HIV-1 Env gp120 Inner Domain Shapes the Phe43 Cavity and the CD4 Binding Site. Mbio. 11. PMID 32457241 DOI: 10.1128/Mbio.00280-20  0.425
2020 Ang CG, Hossain MA, Rajpara M, Bach H, Acharya K, Dick A, Rashad AA, Kutzler M, Abrams CF, Chaiken I. Metastable HIV-1 Surface Protein Env Sensitizes Cell Membranes to Transformation and Poration by Dual-Acting Virucidal Entry Inhibitors. Biochemistry. PMID 31942789 DOI: 10.1021/Acs.Biochem.9B01008  0.348
2019 Aneja R, Grigoletto A, Nangarlia A, Rashad AA, Wrenn S, Jacobson JM, Pasut G, Chaiken I. Pharmacokinetic stability of macrocyclic peptide triazole HIV-1 inactivators alone and in liposomes. Journal of Peptide Science : An Official Publication of the European Peptide Society. e3155. PMID 30809901 DOI: 10.1002/Psc.3155  0.444
2019 Darvish A, Lee JS, Peng B, Saharia J, VenkatKalyana Sundaram R, Goyal G, Bandara N, Ahn CW, Kim J, Dutta P, Chaiken I, Kim MJ. Back Cover: Mechanical characterization of HIV-1 with a solid-state nanopore sensor Electrophoresis. 40: NA-NA. DOI: 10.1002/Elps.201970044  0.304
2018 Darvish A, Lee JS, Saharia J, Sundaram RVK, Goyal G, Bandara N, Ahn CW, Kim J, Dutta P, Chaiken I, Kim MJ. Mechanical characterization of HIV-1 with a solid-state nanopore sensor. Electrophoresis. PMID 30151981 DOI: 10.1002/Elps.201800311  0.316
2018 Rashad AA, Song LR, Holmes AP, Acharya K, Zhang S, Wang ZL, Gary E, Xie X, Pirrone V, Kutzler MA, Long YQ, Chaiken I. Bifunctional Chimera That Coordinately Targets Human Immunodeficiency Virus 1 (HIV-1) Envelope gp120 and Host Cell CCR5 Co-receptor at the Virus-Cell Interface. Journal of Medicinal Chemistry. PMID 29767965 DOI: 10.1021/Acs.Jmedchem.8B00477  0.624
2018 Gossert ST, Parajuli B, Chaiken I, Abrams CF. Roles of Conserved Tryptophans in Trimerization of HIV-1 Membrane-Proximal External Regions: Implications for Virucidal Design via Alchemical Free-Energy Molecular Simulations. Proteins. PMID 29633345 DOI: 10.1002/Prot.25504  0.44
2018 Parajuli B, Acharya K, Bach HC, Parajuli B, Zhang S, Smith AB, Abrams CF, Chaiken I. Restricted HIV-1 Env Glycan Engagement by Lectin-Reengineered DAVEI Protein Chimera is sufficient for Lytic Inactivation of the Virus. The Biochemical Journal. PMID 29343613 DOI: 10.1042/Bcj20170662  0.662
2017 Rashad AA, Acharya K, Haftl A, Aneja R, Dick A, Holmes AP, Chaiken I. Chemical optimization of macrocyclic HIV-1 inactivators for improving potency and increasing the structural diversity at the triazole ring. Organic & Biomolecular Chemistry. PMID 28770939 DOI: 10.1039/C7Ob01448A  0.438
2017 Bastian AR, Ang CG, Kamanna K, Shaheen F, Huang YH, McFadden K, Duffy C, Bailey LD, Sundaram RV, Chaiken I. Targeting cell surface HIV-1 Env protein to suppress infectious virus formation. Virus Research. PMID 28390972 DOI: 10.1016/J.Virusres.2017.04.003  0.621
2017 Acharya K, Rashad AA, Moraca F, Klasse PJ, Moore JP, Abrams C, Chaiken I. Recognition of HIV-Inactivating Peptide Triazoles by the Recombinant Soluble Env Trimer, BG505 SOSIP.664. Proteins. PMID 28056499 DOI: 10.1002/Prot.25238  0.516
2016 Parajuli B, Acharya K, Yu R, Ngo B, Rashad AA, Abrams CF, Chaiken IM. Lytic Inactivation of HIV-1 by Dual Engagement of gp120 and gp41 Domains in the Virus Env Protein Trimer. Biochemistry. PMID 27731975 DOI: 10.1021/Acs.Biochem.6B00570  0.492
2016 Moraca F, Acharya K, Melillo B, Smith Iii AB, Chaiken IM, Abrams CF. Computational evaluation of HIV-1 gp120 conformations of soluble trimeric gp140 structures as targets for de novo docking of first- and second-generation small-molecule CD4 mimics. Journal of Chemical Information and Modeling. PMID 27602436 DOI: 10.1021/Acs.Jcim.6B00393  0.449
2015 Kalyana Sundaram RV, Li H, Bailey LD, Rashad AA, Aneja R, Weiss K, Huynh J, Rosemary Bastian A, Papazoglou ES, Abrams CF, Wrenn SP, Chaiken IM. Impact of HIV-1 Membrane Cholesterol on Cell-Independent Lytic Inactivation and Cellular Infectivity. Biochemistry. PMID 26713837 DOI: 10.1021/Acs.Biochem.5B00936  0.373
2015 Chaiken I, Rashad AA. Peptide triazole inactivators of HIV-1: how do they work and what is their potential? Future Medicinal Chemistry. 7: 2305-10. PMID 26599515 DOI: 10.4155/Fmc.15.152  0.39
2015 Bailey LD, Kalyana Sundaram RV, Li H, Duffy C, Aneja R, Rosemary Bastian A, Holmes AP, Kamanna K, Rashad AA, Chaiken I. Disulfide sensitivity in the Env protein underlies lytic inactivation of HIV-1 by peptide triazole thiols. Acs Chemical Biology. PMID 26458166 DOI: 10.1021/Acschembio.5B00381  0.523
2015 Pustylnikov S, Dave RS, Khan ZK, Porkolab V, Rashad AA, Hutchinson M, Fieschi F, Chaiken I, Jain P. Inhibition of DC-SIGN-Mediated HIV-1 Infection by Complementary Actions of Dendritic Cell Receptor Antagonists and Env-Targeting Virus Inactivators. Aids Research and Human Retroviruses. PMID 26383762 DOI: 10.1089/Aid.2015.0184  0.401
2015 Rashad AA, Kalyana Sundaram RV, Aneja R, Duffy C, Chaiken I. Macrocyclic Envelope Glycoprotein Antagonists that Irreversibly Inactivate HIV-1 before Host Cell Encounter Journal of Medicinal Chemistry. 58: 7603-7608. PMID 26331669 DOI: 10.1021/Acs.Jmedchem.5B00935  0.449
2015 Aneja R, Rashad AA, Li H, Kalyana Sundaram RV, Duffy C, Bailey LD, Chaiken I. Peptide Triazole Inactivators of HIV-1 Utilize a Conserved Two-Cavity Binding Site at the Junction of the Inner and Outer Domains of Env gp120. Journal of Medicinal Chemistry. 58: 3843-58. PMID 25860784 DOI: 10.1021/Acs.Jmedchem.5B00073  0.506
2015 Rosemary Bastian A, Nangarlia A, Bailey LD, Holmes A, Kalyana Sundaram RV, Ang C, Moreira DR, Freedman K, Duffy C, Contarino M, Abrams C, Root M, Chaiken I. Mechanism of multivalent nanoparticle encounter with HIV-1 for potency enhancement of peptide triazole virus inactivation. The Journal of Biological Chemistry. 290: 529-43. PMID 25371202 DOI: 10.1074/Jbc.M114.608315  0.448
2014 Fraietta JA, Mueller YM, Lozenski KL, Ratner D, Boesteanu AC, Hancock AS, Lackman-Smith C, Zentner IJ, Chaiken IM, Chung S, LeGrice SF, Snyder BA, Mankowski MK, Jones NM, Hope JL, et al. Abasic phosphorothioate oligomers inhibit HIV-1 reverse transcription and block virus transmission across polarized ectocervical organ cultures. Antimicrobial Agents and Chemotherapy. 58: 7056-71. PMID 25224013 DOI: 10.1128/Aac.02991-14  0.384
2014 Emileh A, Duffy C, Holmes AP, Rosemary Bastian A, Aneja R, Tuzer F, Rajagopal S, Li H, Abrams CF, Chaiken IM. Covalent conjugation of a peptide triazole to HIV-1 gp120 enables intramolecular binding site occupancy. Biochemistry. 53: 3403-14. PMID 24801282 DOI: 10.1021/Bi500136F  0.48
2014 Courter JR, Madani N, Sodroski J, Schön A, Freire E, Kwong PD, Hendrickson WA, Chaiken IM, LaLonde JM, Smith AB. Structure-based design, synthesis and validation of CD4-mimetic small molecule inhibitors of HIV-1 entry: conversion of a viral entry agonist to an antagonist. Accounts of Chemical Research. 47: 1228-37. PMID 24502450 DOI: 10.1021/Ar4002735  0.484
2013 Bastian AR, Contarino M, Bailey LD, Aneja R, Moreira DRM, Freedman K, McFadden K, Duffy C, Emileh A, Leslie G, Jacobson JM, Hoxie JA, Chaiken I. Interactions of peptide triazole thiols with Env gp120 induce irreversible breakdown and inactivation of HIV-1 virions Retrovirology. 10. PMID 24330857 DOI: 10.1186/1742-4690-10-153  0.678
2013 Li H, Aneja R, Chaiken I. Click chemistry in peptide-based drug design. Molecules (Basel, Switzerland). 18: 9797-817. PMID 23959192 DOI: 10.3390/Molecules18089797  0.318
2013 Contarino M, Bastian AR, Kalyana Sundaram RV, McFadden K, Duffy C, Gangupomu V, Baker M, Abrams C, Chaiken I. Chimeric Cyanovirin-MPER recombinantly engineered proteins cause cell-free virolysis of HIV-1. Antimicrobial Agents and Chemotherapy. 57: 4743-50. PMID 23856780 DOI: 10.1128/Aac.00309-13  0.65
2013 Emileh A, Tuzer F, Yeh H, Umashankara M, Moreira DR, Lalonde JM, Bewley CA, Abrams CF, Chaiken IM. A model of peptide triazole entry inhibitor binding to HIV-1 gp120 and the mechanism of bridging sheet disruption. Biochemistry. 52: 2245-61. PMID 23470147 DOI: 10.1021/Bi400166B  0.482
2013 Kamanna K, Aneja R, Duffy C, Kubinski P, Rodrigo Moreira D, Bailey LD, McFadden K, Schön A, Holmes A, Tuzer F, Contarino M, Freire E, Chaiken IM. Non-natural peptide triazole antagonists of HIV-1 envelope gp120. Chemmedchem. 8: 322-8. PMID 23239505 DOI: 10.1002/Cmdc.201200422  0.67
2013 Freedman KJ, Bastian AR, Chaiken I, Kim MJ. Solid-state nanopore detection of protein complexes: Applications in healthcare and protein kinetics Small. 9: 750-759. PMID 23074081 DOI: 10.1002/Smll.201201423  0.302
2013 Tuzer F, Madani N, Kamanna K, Zentner I, LaLonde J, Holmes A, Upton E, Rajagopal S, McFadden K, Contarino M, Sodroski J, Chaiken I. HIV-1 Env gp120 structural determinants for peptide triazole dual receptor site antagonism. Proteins. 81: 271-90. PMID 23011758 DOI: 10.1002/Prot.24184  0.707
2013 Freedman KJ, Bastian AR, Chaiken I, Kim MJ. HIV Detection: Solid-State Nanopore Detection of Protein Complexes: Applications in Healthcare and Protein Kinetics (Small 5/2013) Small. 9: 645-645. DOI: 10.1002/Smll.201370026  0.316
2012 McFadden K, Fletcher P, Rossi F, Kantharaju, Umashankara M, Pirrone V, Rajagopal S, Gopi H, Krebs FC, Martin-Garcia J, Shattock RJ, Chaiken I. Antiviral breadth and combination potential of peptide triazole HIV-1 entry inhibitors. Antimicrobial Agents and Chemotherapy. 56: 1073-80. PMID 22083481 DOI: 10.1128/Aac.05555-11  0.761
2012 Emileh A, Tuzer F, Moreira DR, LaLonde JM, Bewley CA, Chaiken IM, Abrams CF. A Molecular Dynamics Simulation of Peptide-Triazole HIV Entry Inhibitor Binding to gp120 Hydrophobic Core Biophysical Journal. 102: 621a. DOI: 10.1016/J.Bpj.2011.11.3383  0.506
2011 Ishino T, Economou NJ, McFadden K, Zaks-Zilberman M, Jost M, Baxter S, Contarino MR, Harrington AE, Loll PJ, Pasut G, Lievens S, Tavernier J, Chaiken I. A protein engineering approach differentiates the functional importance of carbohydrate moieties of interleukin-5 receptor α. Biochemistry. 50: 7546-56. PMID 21770429 DOI: 10.1021/Bi2009135  0.775
2011 Bastian AR, Kantharaju, McFadden K, Duffy C, Rajagopal S, Contarino MR, Papazoglou E, Chaiken I. Cell-free HIV-1 virucidal action by modified peptide triazole inhibitors of Env gp120. Chemmedchem. 6: 1335-9, 1318. PMID 21714095 DOI: 10.1002/Cmdc.201100177  0.704
2011 Gift SK, McFadden K, Zentner IJ, Rajagopal S, Zhang MY, Dimitrov DS, Chaiken IM. Monoclonal antibody m18 paratope leading to dual receptor antagonism of HIV-1 gp120. Biochemistry. 50: 2769-79. PMID 21417283 DOI: 10.1021/Bi101161J  0.795
2011 Gift SK, Zentner IJ, Schön A, McFadden K, Umashankara M, Rajagopal S, Contarino M, Duffy C, Courter JR, Zhang MY, Gershoni JM, Cocklin S, Dimitrov DS, Smith AB, Freire E, ... Chaiken IM, et al. Conformational and structural features of HIV-1 gp120 underlying the dual receptor antagonism by cross-reactive neutralizing antibody m18. Biochemistry. 50: 2756-68. PMID 21351734 DOI: 10.1021/Bi101160R  0.793
2011 Bastian AR, Kantharaju, McFadden K, Duffy C, Rajagopal S, Contarino MR, Papazoglou E, Chaiken I. Inside Cover: Cell‐Free HIV‐1 Virucidal Action by Modified Peptide Triazole Inhibitors of Env gp120 (ChemMedChem 8/2011) Chemmedchem. 6: 1318-1318. DOI: 10.1002/Cmdc.201190033  0.622
2010 Umashankara M, McFadden K, Zentner I, Schön A, Rajagopal S, Tuzer F, Kuriakose SA, Contarino M, Lalonde J, Freire E, Chaiken I. The active core in a triazole peptide dual-site antagonist of HIV-1 gp120 Chemmedchem. 5: 1871-1879. PMID 20677318 DOI: 10.1002/Cmdc.201000222  0.702
2010 Lee HS, Contarino M, Umashankara M, Schön A, Freire E, Smith AB, Chaiken IM, Penn LS. Use of the quartz crystal microbalance to monitor ligand-induced conformational rearrangements in HIV-1 envelope protein gp120. Analytical and Bioanalytical Chemistry. 396: 1143-52. PMID 20016882 DOI: 10.1007/S00216-009-3313-8  0.447
2009 Gopi H, Cocklin S, Pirrone V, McFadden K, Tuzer F, Zentner I, Ajith S, Baxter S, Jawanda N, Krebs FC, Chaiken IM. Introducing metallocene into a triazole peptide conjugate reduces its off-rate and enhances its affinity and antiviral potency for HIV-1 gp120. Journal of Molecular Recognition : Jmr. 22: 169-74. PMID 18498083 DOI: 10.1002/Jmr.892  0.798
2008 Cannon G, Yi Y, Ni H, Stoddard E, Scales DA, Van Ryk DI, Chaiken I, Malamud D, Weissman D. HIV envelope binding by macrophage-expressed gp340 promotes HIV-1 infection. Journal of Immunology (Baltimore, Md. : 1950). 181: 2065-70. PMID 18641344 DOI: 10.4049/Jimmunol.181.3.2065  0.429
2008 Ishino T, Harrington AE, Gopi H, Chaiken I. Structure-based rationale for interleukin 5 receptor antagonism Current Pharmaceutical Design. 14: 1231-1239. PMID 18473871 DOI: 10.2174/138161208784246144  0.676
2008 Kamat V, Donaldson JM, Kari C, Quadros MR, Lelkes PI, Chaiken I, Cocklin S, Williams JC, Papazoglou E, Rodeck U. Enhanced EGFR inhibition and distinct epitope recognition by EGFR antagonistic mAbs C225 and 425. Cancer Biology & Therapy. 7: 726-33. PMID 18424917 DOI: 10.4161/Cbt.7.5.6097  0.33
2008 Gopi H, Umashankara M, Pirrone V, LaLonde J, Madani N, Tuzer F, Baxter S, Zentner I, Cocklin S, Jawanda N, Miller SR, Schön A, Klein JC, Freire E, Krebs FC, ... ... Chaiken I, et al. Structural determinants for affinity enhancement of a dual antagonist peptide entry inhibitor of human immunodeficiency virus type-1 Journal of Medicinal Chemistry. 51: 2638-2647. PMID 18402432 DOI: 10.1021/Jm070814R  0.732
2008 Zaks-Zilberman M, Harrington AE, Ishino T, Chaiken IM. Interleukin-5 receptor subunit oligomerization and rearrangement revealed by fluorescence resonance energy transfer imaging. The Journal of Biological Chemistry. 283: 13398-406. PMID 18326494 DOI: 10.1074/Jbc.M710230200  0.76
2008 Ishino T, Harrington AE, Zaks-Zilberman M, Scibek JJ, Chaiken I. Slow-dissociation effect of common signaling subunit beta c on IL5 and GM-CSF receptor assembly. Cytokine. 42: 179-90. PMID 18294864 DOI: 10.1016/J.Cyto.2007.12.010  0.768
2007 McFadden K, Cocklin S, Gopi H, Baxter S, Ajith S, Mahmood N, Shattock R, Chaiken I. A recombinant allosteric lectin antagonist of HIV-1 envelope gp120 interactions. Proteins. 67: 617-29. PMID 17348010 DOI: 10.1002/Prot.21295  0.785
2007 Cocklin S, Gopi H, Querido B, Nimmagadda M, Kuriakose S, Cicala C, Ajith S, Baxter S, Arthos J, Martín-García J, Chaiken IM. Broad-spectrum anti-human immunodeficiency virus (HIV) potential of a peptide HIV type 1 entry inhibitor. Journal of Virology. 81: 3645-8. PMID 17251295 DOI: 10.1128/Jvi.01778-06  0.675
2007 Bhattacharya M, Pillalamari U, Sarkhel S, Ishino T, Urbina C, Jameson B, Chaiken I. Recruitment pharmacophore for interleukin 5 receptor α antagonism Biopolymers - Peptide Science Section. 88: 83-93. PMID 17041908 DOI: 10.1002/Bip.20612  0.406
2006 Yang X, Lipchina I, Cocklin S, Chaiken I, Sodroski J. Antibody binding is a dominant determinant of the efficiency of human immunodeficiency virus type 1 neutralization. Journal of Virology. 80: 11404-8. PMID 16956933 DOI: 10.1128/Jvi.01102-06  0.407
2006 Gopi HN, Tirupula KC, Baxter S, Ajith S, Chaiken IM. Click chemistry on azidoproline: high-affinity dual antagonist for HIV-1 envelope glycoprotein gp120. Chemmedchem. 1: 54-7. PMID 16892335 DOI: 10.1002/Cmdc.200500037  0.696
2006 Baxter SC, Panarello D, Ajith S, Bhattacharya M, Chaiken IM. Recombinant-protein production in insect cells utilizing a hollow-fibre bioreactor. Biotechnology and Applied Biochemistry. 45: 167-72. PMID 16872272 DOI: 10.1042/Ba20060074  0.306
2006 Contarino MR, Sergi M, Harrington AE, Lazareck A, Xu J, Chaiken I. Modular, self-assembling peptide linkers for stable and regenerable carbon nanotube biosensor interfaces. Journal of Molecular Recognition : Jmr. 19: 363-71. PMID 16775846 DOI: 10.1002/Jmr.783  0.371
2006 Cocklin S, Jost M, Robertson NM, Weeks SD, Weber HW, Young E, Seal S, Zhang C, Mosser E, Loll PJ, Saunders AJ, Rest RF, Chaiken IM. Real-time monitoring of the membrane-binding and insertion properties of the cholesterol-dependent cytolysin anthrolysin O from Bacillus anthracis. Journal of Molecular Recognition : Jmr. 19: 354-62. PMID 16775845 DOI: 10.1002/Jmr.784  0.331
2006 Ishino T, Pillalamarri U, Panarello D, Bhattacharya M, Urbina C, Horvat S, Sarkhel S, Jameson B, Chaiken I. Asymmetric usage of antagonist charged residues drives interleukin-5 receptor recruitment but is insufficient for receptor activation Biochemistry. 45: 1106-1115. PMID 16430207 DOI: 10.1021/Bi0518038  0.428
2005 Ishino T, Robertson N, Chaiken I. Cytokine Recognition by Human Interleukin 5 Receptor Vitamins and Hormones. 71: 321-344. PMID 16112273 DOI: 10.1016/S0083-6729(05)71011-6  0.352
2005 Martín-García J, Cocklin S, Chaiken IM, González-Scarano F. Interaction with CD4 and antibodies to CD4-induced epitopes of the envelope gp120 from a microglial cell-adapted human immunodeficiency virus type 1 isolate. Journal of Virology. 79: 6703-13. PMID 15890908 DOI: 10.1128/Jvi.79.11.6703-6713.2005  0.408
2005 Ishino T, Urbina C, Bhattacharya M, Panarello D, Chaiken I. Receptor epitope usage by an interleukin-5 mimetic peptide Journal of Biological Chemistry. 280: 22951-22961. PMID 15826943 DOI: 10.1074/Jbc.M502341200  0.451
2005 Colleluori DM, Tien D, Kang F, Pagliei T, Kuss R, McCormick T, Watson K, McFadden K, Chaiken I, Buckheit RW, Romano JW. Expression, purification, and characterization of recombinant cyanovirin-N for vaginal anti-HIV microbicide development. Protein Expression and Purification. 39: 229-36. PMID 15642474 DOI: 10.1016/J.Pep.2004.10.009  0.606
2004 Si Z, Madani N, Cox JM, Chruma JJ, Klein JC, Schön A, Phan N, Wang L, Biorn AC, Cocklin S, Chaiken I, Freire E, Smith AB, Sodroski JG. Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins. Proceedings of the National Academy of Sciences of the United States of America. 101: 5036-41. PMID 15051887 DOI: 10.1073/Pnas.0307953101  0.486
2004 Ruchala P, Varadi G, Ishino T, Scibek J, Bhattacharya M, Urbina C, Van Ryk D, Uings I, Chaiken I. Cyclic Peptide Interleukin 5 Antagonists Mimic CD Turn Recognition Epitope for Receptor α Biopolymers. 73: 556-568. PMID 15048779 DOI: 10.1002/Bip.20001  0.434
2004 Biorn AC, Cocklin S, Madani N, Si Z, Ivanovic T, Samanen J, Van Ryk DI, Pantophlet R, Burton DR, Freire E, Sodroski J, Chaiken IM. Mode of action for linear peptide inhibitors of HIV-1 gp120 interactions. Biochemistry. 43: 1928-38. PMID 14967033 DOI: 10.1021/Bi035088I  0.498
2004 Leavitt SA, SchOn A, Klein JC, Manjappara U, Chaiken IM, Freire E. Interactions of HIV-1 proteins gp120 and Nef with cellular partners define a novel allosteric paradigm. Current Protein & Peptide Science. 5: 1-8. PMID 14965316 DOI: 10.2174/1389203043486955  0.451
2004 Ishino T, Pasut G, Scibek J, Chaiken I. Kinetic Interaction Analysis of Human Interleukin 5 Receptor α Mutants Reveals a Unique Binding Topology and Charge Distribution for Cytokine Recognition Journal of Biological Chemistry. 279: 9547-9556. PMID 14662768 DOI: 10.1074/Jbc.M309327200  0.353
2004 Wu SJ, Chaiken I. Biosensor analysis of receptor-ligand interactions Methods in Molecular Biology (Clifton, N.J.). 249: 93-110. PMID 14573894 DOI: 10.1385/1-59259-667-3:93  0.326
2003 Wu Z, Van Ryk D, Davis C, Abrams WR, Chaiken I, Magnani J, Malamud D. Salivary agglutinin inhibits HIV type 1 infectivity through interaction with viral glycoprotein 120 Aids Research and Human Retroviruses. 19: 201-209. PMID 12689412 DOI: 10.1089/088922203763315704  0.496
2002 Kwong PD, Doyle ML, Casper DJ, Cicala C, Leavitt SA, Majeed S, Steenbeke TD, Venturi M, Chaiken I, Fung M, Katinger H, Parren PWIH, Robinson J, Van Ryk D, Wang L, et al. HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites Nature. 420: 678-682. PMID 12478295 DOI: 10.1038/Nature01188  0.479
2002 Monfardini C, Canziani G, Plugariu C, Kieber-Emmons T, Godillot AP, Kwah J, Bajgier J, Chaiken I, Williams WV. Structure-based design of mimetics for granulocyte-macrophage colony stimulating factor (GM-CSF) Current Pharmaceutical Design. 8: 2185-2199. PMID 12369862 DOI: 10.2174/1381612023393198  0.328
2002 Scibek JJ, Evergren E, Zahn S, Canziani GA, Van Ryk D, Chaiken IM. Biosensor analysis of dynamics of interleukin 5 receptor subunit beta(c) interaction with IL5:IL5R(alpha) complexes. Analytical Biochemistry. 307: 258-65. PMID 12202242 DOI: 10.1016/S0003-2697(02)00043-X  0.332
2002 Dowd CS, Leavitt S, Babcock G, Godillot AP, Van Ryk D, Canziani GA, Sodroski J, Freire E, Chaiken IM. Beta-turn Phe in HIV-1 Env binding site of CD4 and CD4 mimetic miniprotein enhances Env binding affinity but is not required for activation of co-receptor/17b site. Biochemistry. 41: 7038-46. PMID 12033937 DOI: 10.1021/Bi012168I  0.493
2002 Li C, Plugariu CG, Bajgier J, White JR, Liefer KM, Wu SJ, Chaiken I. Coiled coil miniprotein randomization on phage leads to charge pattern mimicry of the receptor recognition determinant of interleukin 5 Journal of Molecular Recognition. 15: 33-43. PMID 11870920 DOI: 10.1002/Jmr.558  0.364
2001 Chaiken I. Revealing and utilizing receptor recognition mechanisms in a high-throughput world Journal of Cellular Biochemistry. 84: 126-135. PMID 11842438 DOI: 10.1002/Jcb.10079  0.411
2001 Li C, Dowd CS, Zhang W, Chaiken IM. Phage randomization in a charybdotoxin scaffold leads to CD4-mimetic recognition motifs that bind HIV-1 envelope through non-aromatic sequences. The Journal of Peptide Research : Official Journal of the American Peptide Society. 57: 507-18. PMID 11437954 DOI: 10.1046/J.1397-002X.2001.00876.X  0.467
2001 Dowd CS, Zhang W, Li C, Chaiken IM. From receptor recognition mechanisms to bioinspired mimetic antagonists in HIV-1/cell docking. Journal of Chromatography. B, Biomedical Sciences and Applications. 753: 327-35. PMID 11334348 DOI: 10.1016/S0378-4347(00)00567-3  0.477
2001 Zhang W, Godillot AP, Wyatt R, Sodroski J, Chaiken I. Antibody 17b binding at the coreceptor site weakens the kinetics of the interaction of envelope glycoprotein gp120 with CD4 Biochemistry. 40: 1662-1670. PMID 11327825 DOI: 10.1021/Bi001397M  0.455
2001 Zabeau L, Van der Heyden J, Broekaert D, Verhee A, Vandekerckhove J, Wu SJ, Chaiken I, Heinrich P, Behrmann I, Tavernier J. Neutralizing monoclonal antibodies can potentiate IL-5 signaling European Journal of Immunology. 31: 1087-1097. PMID 11298333 DOI: 10.1002/1521-4141(200104)31:4<1087::Aid-Immu1087>3.0.Co;2-Q  0.341
2000 Plugariu CG, Wu SJ, Zhang W, Chaiken I. Multisite mutagenesis of interleukin 5 differentiates sites for receptor recognition and receptor activation Biochemistry. 39: 14939-14949. PMID 11101310 DOI: 10.1021/Bi001467P  0.415
2000 O'Keefe BR, Shenoy SR, Xie D, Zhang W, Muschik JM, Currens MJ, Chaiken I, Boyd MR. Analysis of the interaction between the HIV-inactivating protein cyanovirin-N and soluble forms of the envelope glycoproteins gp120 and gp41. Molecular Pharmacology. 58: 982-92. PMID 11040045 DOI: 10.1124/MOL.58.5.982  0.318
2000 Zahn S, Godillot P, Yoshimura A, Chaiken I. IL-5-induced JAB-JAK2 interaction Cytokine. 12: 1299-1306. PMID 10975987 DOI: 10.1006/Cyto.2000.0718  0.337
2000 Wilchek M, Chaiken I. An overview of affinity chromatography Methods in Molecular Biology (Clifton, N.J.). 147: 1-6. PMID 10857080 DOI: 10.1007/978-1-60327-261-2_1  0.324
2000 Sheng N, Fairbanks MB, Heinrikson RL, Canziani G, Chaiken IM, Mosser DM, Zhang H, Colman RW. Cleaved high molecular weight kininogen binds directly to the integrin CD11b/CD18 (Mac-1) and blocks adhesion to fibrinogen and ICAM-1. Blood. 95: 3788-95. PMID 10845911 DOI: 10.1182/Blood.V95.12.3788.012K47_3788_3795  0.365
2000 Wu SJ, Tambyraja R, Zhang W, Zahn S, Godillot AP, Chaiken I. Epitope randomization redefines the functional role of glutamic acid 110 in interleukin-5 receptor activation Journal of Biological Chemistry. 275: 7351-7358. PMID 10702307 DOI: 10.1074/Jbc.275.10.7351  0.382
1999 Canziani G, Zhang W, Cines D, Rux A, Willis S, Cohen G, Eisenberg R, Chaiken I. Exploring biomolecular recognition using optical biosensors Methods: a Companion to Methods in Enzymology. 19: 253-269. PMID 10527730 DOI: 10.1006/Meth.1999.0855  0.321
1999 Zhang W, Canziani G, Plugariu C, Wyatt R, Sodroski J, Sweet R, Kwong P, Hendrickson W, Chaiken I. Conformational changes of gp120 in epitopes near the CCR5 binding site are induced by CD4 and a CD4 miniprotein mimetic Biochemistry. 38: 9405-9416. PMID 10413516 DOI: 10.1021/Bi990654O  0.434
1999 Wu SJ, Li J, Tsui P, Cook R, Zhang W, Hu Y, Canziani G, Chaiken I. Randomization of the receptor α chain recruitment epitope reveals a functional interleukin-5 with charge depletion in the CD loop Journal of Biological Chemistry. 274: 20479-20488. PMID 10400676 DOI: 10.1074/Jbc.274.29.20479  0.403
1999 Hoffman TL, LaBranche CC, Zhang W, Canziani G, Robinson J, Chaiken I, Hoxie JA, Doms RW. Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein. Proceedings of the National Academy of Sciences of the United States of America. 96: 6359-64. PMID 10339592 DOI: 10.1073/Pnas.96.11.6359  0.456
1999 Bdeir K, Cane W, Canziani G, Chaiken I, Weisel J, Koschinsky ML, Lawn RM, Bannerman PG, Sachais BS, Kuo A, Hancock MA, Tomaszewski J, Raghunath PN, Ganz T, Higazi AA, et al. Defensin Promotes the Binding of Lipoprotein(a) to Vascular Matrix Blood. 94: 2007-2019. DOI: 10.1182/Blood.V94.6.2007.418K12_2007_2019  0.311
1998 Monfardini C, Ramamoorthy M, Rosenbaum H, Fang Q, Godillot PA, Canziani G, Chaiken IM, Williams WV. Construction and binding kinetics of a soluble granulocyte-macrophage colony-stimulating factor receptor alpha-chain-Fc fusion protein. The Journal of Biological Chemistry. 273: 7657-67. PMID 9516471 DOI: 10.1074/Jbc.273.13.7657  0.368
1998 Fan Z, Larson PJ, Bognacki J, Raghunath PN, Tomaszewski JE, Kuo A, Canziani G, Chaiken I, Cines DB, Higazi AAR. Tissue factor regulates plasminogen binding and activation Blood. 91: 1987-1998. PMID 9490681 DOI: 10.1182/Blood.V91.6.1987  0.353
1997 Li J, Cook R, Doyle ML, Hensley P, McNulty DE, Chaiken I. Monomeric isomers of human interleukin 5 show that 1:1 receptor recruitment is sufficient for function Proceedings of the National Academy of Sciences of the United States of America. 94: 6694-6699. PMID 9192627 DOI: 10.1073/Pnas.94.13.6694  0.37
1997 Myszka DG, Morton TA, Doyle ML, Chaiken IM. Kinetic analysis of a protein antigen-antibody interaction limited by mass transport on an optical biosensor. Biophysical Chemistry. 64: 127-37. PMID 9127943 DOI: 10.1016/S0301-4622(96)02230-2  0.325
1996 Li J, Cook R, Chaiken I. Interleukin 5 Interactions with Soluble and Cell Surface Forms of its Receptor Journal of Molecular Recognition. 9: 347-355. PMID 9174908 DOI: 10.1002/(Sici)1099-1352(199634/12)9:5/6<347::Aid-Jmr323>3.0.Co;2-9  0.324
1996 Wu H, Myszka DG, Tendian SW, Brouillette CG, Sweet RW, Chaiken IM, Hendrickson WA. Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding. Proceedings of the National Academy of Sciences of the United States of America. 93: 15030-5. PMID 8986758 DOI: 10.1073/Pnas.93.26.15030  0.467
1996 Li J, Cook R, Chaiken I. Mutants of single chain interleukin 5 show asymmetric recruitment of receptor α and β(c) subunits Journal of Biological Chemistry. 271: 31729-31734. PMID 8940197 DOI: 10.1074/Jbc.271.49.31729  0.401
1996 Doyle ML, Myszka DG, Chaiken IM. Molecular interaction analysis in ligand design using mass transport, kinetic and thermodynamic methods. Journal of Molecular Recognition : Jmr. 9: 65-74. PMID 8877796 DOI: 10.1002/(Sici)1099-1352(199603)9:2<65::Aid-Jmr245>3.0.Co;2-B  0.323
1996 It J, Cook R, Dede K, Chaiken I. Single chain human interleukin 5 and its asymmetric mutagenesis for mapping receptor binding sites Faseb Journal. 10: A1376. DOI: 10.1074/Jbc.271.4.1817  0.385
1996 Chaiken I, Myszka D, Morton T. New Opportunities for Using Immobilized Ligands to Characterize Macromolecular Recognition and Design Recognition Molecules Advances in Molecular and Cell Biology. 15: 553-568. DOI: 10.1016/S1569-2558(08)60136-8  0.369
1995 Tendian SW, Myszka DG, Sweet RW, Chaiken IM, Brouillette CG. Interdomain communication of T-cell CD4 studied by absorbance and fluorescence difference spectroscopy measurements of urea-induced unfolding. Biochemistry. 34: 6464-74. PMID 7756278 DOI: 10.1021/Bi00019A028  0.304
1995 Jones C, Patel A, Griffin S, Martin J, Young P, O'Donnell K, Silverman C, Porter T, Chaiken I. Current trends in molecular recognition and bioseparation. Journal of Chromatography. A. 707: 3-22. PMID 7633593 DOI: 10.1016/0021-9673(95)00466-Z  0.326
1995 Bennett D, Morton T, Breen A, Hertzberg R, Cusimano D, Appelbaum E, McDonnell P, Young P, Matico R, Chaiken I. Kinetic characterization of the interaction of biotinylated human interleukin 5 with an Fc chimera of its receptor alpha subunit and development of an ELISA screening assay using real-time interaction biosensor analysis. Journal of Molecular Recognition : Jmr. 8: 52-8. PMID 7598953 DOI: 10.1002/Jmr.300080109  0.402
1995 Morton T, Li J, Cook R, Chaiken I. Mutagenesis in the C-terminal region of human interleukin 5 reveals a central patch for receptor alpha chain recognition Proceedings of the National Academy of Sciences of the United States of America. 92: 10879-10883. PMID 7479902 DOI: 10.1073/Pnas.92.24.10879  0.374
1994 Myszka DG, Chaiken IM. Design and characterization of an intramolecular antiparallel coiled coil peptide. Biochemistry. 33: 2363-72. PMID 8117695 DOI: 10.1021/Bi00175A003  0.37
1994 Morton TA, Bennett DB, Appelbaum ER, Cusimano DM, Johanson KO, Matico RE, Young PR, Doyle M, Chaiken IM. Analysis of the interaction between human interleukin-5 and the soluble domain of its receptor using a surface plasmon resonance biosensor. Journal of Molecular Recognition : Jmr. 7: 47-55. PMID 7986567 DOI: 10.1002/Jmr.300070107  0.377
1992 Rosé S, Hensley P, O'Shannessy DJ, Culp J, Debouck C, Chaiken I. Characterization of HIV-1 p24 self-association using analytical affinity chromatography. Proteins. 13: 112-9. PMID 1620693 DOI: 10.1002/Prot.340130204  0.376
1992 Tropsha A, Kizer JS, Chaiken IM. Making sense from antisense: a review of experimental data and developing ideas on sense--antisense peptide recognition. Journal of Molecular Recognition : Jmr. 5: 43-54. PMID 1472380 DOI: 10.1002/Jmr.300050202  0.378
1989 Fassina G, Zamai M, Brigham-Burke M, Chaiken IM. Recognition properties of antisense peptides to Arg8-vasopressin/bovine neurophysin II biosynthetic precursor sequences. Biochemistry. 28: 8811-8. PMID 2605222 DOI: 10.1021/Bi00448A020  0.386
1989 Shai Y, Brunck TK, Chaiken IM. Antisense peptide recognition of sense peptides: sequence simplification and evaluation of forces underlying the interaction. Biochemistry. 28: 8804-11. PMID 2605221 DOI: 10.1021/Bi00448A019  0.58
1988 Chaiken IM, Shai Y, Fassina G, Caliceti P. Current development of analytical affinity chromatography: Design and biotechnological uses of molecular recognition surfaces Makromolekulare Chemie. Macromolecular Symposia. 17: 269-279. DOI: 10.1002/Masy.19880170119  0.518
1987 Shai Y, Flashner M, Chaiken IM. Anti-sense peptide recognition of sense peptides: direct quantitative characterization with the ribonuclease S-peptide system using analytical high-performance affinity chromatography. Biochemistry. 26: 669-75. PMID 3567139 DOI: 10.1021/Bi00377A002  0.558
1986 Swaisgood HE, Chaiken IM. Analytical high-performance affinity chromatography: evaluation by studies of neurophysin self-association and neurophysin-peptide hormone interaction using glass matrices. Biochemistry. 25: 4148-55. PMID 3741847 DOI: 10.1021/Bi00362A024  0.329
1985 Kanmera T, Chaiken IM. Molecular properties of the oxytocin/bovine neurophysin biosynthetic precursor. Studies using a semisynthetic precursor. The Journal of Biological Chemistry. 260: 8474-82. PMID 4008499  0.309
1985 Taylor HC, Komoriya A, Chaiken IM. Crystallographic structure of an active, sequence-engineered ribonuclease. Proceedings of the National Academy of Sciences of the United States of America. 82: 6423-6. PMID 3863103 DOI: 10.1073/Pnas.82.19.6423  0.367
1985 Shoemaker KR, Kim PS, Brems DN, Marqusee S, York EJ, Chaiken IM, Stewart JM, Baldwin RL. Nature of the charged-group effect on the stability of the C-peptide helix. Proceedings of the National Academy of Sciences of the United States of America. 82: 2349-53. PMID 3857585 DOI: 10.1073/Pnas.82.8.2349  0.323
1985 Vita C, Fontana A, Chaiken IM. Folding of thermolysin fragments. Correlation between conformational stability and antigenicity of carboxyl-terminal fragments. European Journal of Biochemistry / Febs. 151: 191-6. PMID 2411552 DOI: 10.1111/J.1432-1033.1985.Tb09085.X  0.34
1984 Chaiken IM. Peptides 1982—Proceedings of the 17th European Peptide Symposium Analytical Biochemistry. 136: 536. DOI: 10.1016/0003-2697(84)90260-4  0.307
1982 Chaiken IM, Komoriya A, Ohno M, Widmer F. Use of enzymes in peptide synthesis. Applied Biochemistry and Biotechnology. 7: 385-99. PMID 24234364 DOI: 10.1007/Bf02798320  0.304
1982 Abercrombie DM, Hough CJ, Seeman JR, Brownstein MJ, Gainer H, Russell JT, Chaiken IM. Use of reverse-phase high-performance liquid chromatography in structural studies of neurophysins, photolabeled derivatives, and biosynthetic precursors. Analytical Biochemistry. 125: 395-405. PMID 7181098 DOI: 10.1016/0003-2697(82)90021-5  0.324
1982 Abercrombie DM, Angal S, Sequeira RP, Chaiken IM. Effects of limited tryptic proteolysis of bovine neurophysins on molecular properties of hormone binding, self-association, and antigenicity. Biochemistry. 21: 6458-65. PMID 7150567 DOI: 10.1021/Bi00268A022  0.342
1982 Angal S, Chaiken IM. Interdependence of neurophysin self-association and neuropeptide hormone binding as expressed by quantitative affinity chromatography. Biochemistry. 21: 1574-80. PMID 7082636 DOI: 10.1021/Bi00536A017  0.384
1982 Homandberg GA, Komoriya A, Chaiken IM. Enzymatic condensation of nonassociated peptide fragments using a molecular trap. Biochemistry. 21: 3385-9. PMID 7052121 DOI: 10.1021/Bi00257A021  0.37
1982 Vita C, Fontana A, Chaiken IM. Domain characteristics of the carboxyl-terminal fragment 206-316 of thermolysin: immunochemical studies. Biochemistry. 21: 2016-22. PMID 6178430 DOI: 10.1021/Bi00538A007  0.344
1981 Burns PF, Campagnoni CW, Chaiken IM, Campagnoni AT. Interactions of free and immobilized myelin basic protein with anionic detergents. Biochemistry. 20: 2463-9. PMID 6165382 DOI: 10.1021/Bi00512A016  0.336
1979 Eilat D, Chaiken IM, McCormick WM. Expression of multivalency in the affinity chromatography of antibodies. Appendix: Derivation and evaluation of equations for independent bivalent interacting systems in quantitative affinity chromatography. Biochemistry. 18: 790-5. PMID 420816 DOI: 10.1021/Bi00572A008  0.391
1979 Giudice LC, Chaiken IM. Immunological and chemical identification of a neurophysin-containing protein coded by messenger RNA from bovine hypothalamus. Proceedings of the National Academy of Sciences of the United States of America. 76: 3800-4. PMID 291040 DOI: 10.1073/Pnas.76.8.3800  0.328
1975 Dunn BM, Chaiken IM. Relationship between alpha-helical propensity and formation of the ribonuclease-S complex. Journal of Molecular Biology. 95: 497-511. PMID 1152063 DOI: 10.1016/0022-2836(75)90313-7  0.426
1975 Dunn BM, Chaiken IM. Evaluation of quantitative affinity chromatography by comparison with kinetic and equilibrium dialysis methods for the analysis of nucleotide binding to staphylococcal nuclease. Biochemistry. 14: 2343-9. PMID 1138865 DOI: 10.1021/Bi00682A011  0.531
1974 Dunn BM, Chaiken IM. Quantitative affinity chromatography. Determination of binding constants by elution with competitive inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 71: 2382-5. PMID 4526212 DOI: 10.1073/Pnas.71.6.2382  0.584
1974 Dunn BM, DiBello C, Kirk KL, Cohen LA, Chaiken IM. Synthesis, purification, and properties of a semisynthetic ribonuclease S incorporating 4-fluoro-L-histidine at position 12. The Journal of Biological Chemistry. 249: 6295-301. PMID 4420810  0.405
1973 Sánchez GR, Chaiken IM, Anfinsen CB. Structure-function relationships at the active site of nuclease-T'. The Journal of Biological Chemistry. 248: 3653-9. PMID 4349872  0.451
1973 Dunn BM, DiBello C, Chaiken IM. Semisynthetic histidinyl 12 analogue complexes of ribonuclease S' Federation Proceedings. 32: 1818.  0.405
1971 Chaiken IM, Anfinsen CB. Solic phase synthetic study of the active site region of staphylococcal nuclease-T'. The Journal of Biological Chemistry. 246: 2285-90. PMID 5576073  0.449
1970 Mitchel RE, Chaiken IM, Smith EL. The complete amino acid sequence of papain. Additions and corrections. The Journal of Biological Chemistry. 245: 3485-92. PMID 5470818  0.424
1970 Chaiken IM, Anfinsen CB. A solid phase synthetic study of structure-function relationships in the amino-terminal region of staphylococcal nuclease. The Journal of Biological Chemistry. 245: 4718-23. PMID 5456145  0.457
1970 Chaiken IM, Anfinsen CB. A study of the role of histidine residue 46 in staphylococcal nuclease by solid phase peptide synthesis. The Journal of Biological Chemistry. 245: 2337-41. PMID 5442274  0.494
1969 Chaiken IM, Smith EL. Reaction of a specific tyrosine residue of papain with diisopropylfluorophosphate. The Journal of Biological Chemistry. 244: 4247-50. PMID 5800444  0.459
1969 Chaiken IM, Smith EL. Reaction of the sulfhydryl group of papain with chloroacetic acid. The Journal of Biological Chemistry. 244: 5095-9. PMID 5344123  0.409
1969 Chaiken IM, Smith EL. Reaction of chloroacetamide with the sulfhydryl group of papain. The Journal of Biological Chemistry. 244: 5087-94. PMID 5344122  0.407
Show low-probability matches.