cached image

Irwin M. Chaiken - Publications

Biochemistry Drexel University College of Medicine, Philadelphia, PA, United States 
protein recognition, protein machine that controls HIV-1 cell entry into host cells

198 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Kalyana Sundaram RV, Li H, Bailey LD, Rashad AA, Aneja R, Weiss K, Huynh J, Rosemary Bastian A, Papazoglou ES, Abrams CF, Wrenn SP, Chaiken IM. Impact of HIV-1 Membrane Cholesterol on Cell-Independent Lytic Inactivation and Cellular Infectivity. Biochemistry. PMID 26713837 DOI: 10.1021/acs.biochem.5b00936  1
2015 Bailey LD, Kalyana Sundaram RV, Li H, Duffy C, Aneja R, Rosemary Bastian A, Holmes AP, Kamanna K, Rashad AA, Chaiken I. Disulfide sensitivity in the Env protein underlies lytic inactivation of HIV-1 by peptide triazole thiols. Acs Chemical Biology. PMID 26458166 DOI: 10.1021/acschembio.5b00381  1
2015 Rashad AA, Kalyana Sundaram RV, Aneja R, Duffy C, Chaiken I. Macrocyclic Envelope Glycoprotein Antagonists that Irreversibly Inactivate HIV-1 before Host Cell Encounter Journal of Medicinal Chemistry. 58: 7603-7608. PMID 26331669 DOI: 10.1021/acs.jmedchem.5b00935  1
2015 Aneja R, Rashad AA, Li H, Kalyana Sundaram RV, Duffy C, Bailey LD, Chaiken I. Peptide Triazole Inactivators of HIV-1 Utilize a Conserved Two-Cavity Binding Site at the Junction of the Inner and Outer Domains of Env gp120. Journal of Medicinal Chemistry. 58: 3843-58. PMID 25860784 DOI: 10.1021/acs.jmedchem.5b00073  1
2015 Rosemary Bastian A, Nangarlia A, Bailey LD, Holmes A, Kalyana Sundaram RV, Ang C, Moreira DR, Freedman K, Duffy C, Contarino M, Abrams C, Root M, Chaiken I. Mechanism of multivalent nanoparticle encounter with HIV-1 for potency enhancement of peptide triazole virus inactivation. The Journal of Biological Chemistry. 290: 529-43. PMID 25371202 DOI: 10.1074/jbc.M114.608315  1
2015 Chaiken I, Rashad AA. Peptide triazole inactivators of HIV-1: How do they work and what is their potential Future Medicinal Chemistry. 7: 2305-2310. DOI: 10.4155/fmc.15.152  1
2014 Fraietta JA, Mueller YM, Lozenski KL, Ratner D, Boesteanu AC, Hancock AS, Lackman-Smith C, Zentner IJ, Chaiken IM, Chung S, LeGrice SF, Snyder BA, Mankowski MK, Jones NM, Hope JL, et al. Abasic phosphorothioate oligomers inhibit HIV-1 reverse transcription and block virus transmission across polarized ectocervical organ cultures. Antimicrobial Agents and Chemotherapy. 58: 7056-71. PMID 25224013 DOI: 10.1128/AAC.02991-14  1
2014 Emileh A, Duffy C, Holmes AP, Rosemary Bastian A, Aneja R, Tuzer F, Rajagopal S, Li H, Abrams CF, Chaiken IM. Covalent conjugation of a peptide triazole to HIV-1 gp120 enables intramolecular binding site occupancy. Biochemistry. 53: 3403-14. PMID 24801282 DOI: 10.1021/bi500136f  1
2014 Courter JR, Madani N, Sodroski J, Schön A, Freire E, Kwong PD, Hendrickson WA, Chaiken IM, LaLonde JM, Smith AB. Structure-based design, synthesis and validation of CD4-mimetic small molecule inhibitors of HIV-1 entry: conversion of a viral entry agonist to an antagonist. Accounts of Chemical Research. 47: 1228-37. PMID 24502450 DOI: 10.1021/ar4002735  1
2014 Contarino M, Bastian AR, Kalyana Sundaram RV, McFadden K, Duffy C, Gangupomu V, Baker M, Abrams C, Chaiken I. Chimeric cyanovirin-MPER recombinantly engineered proteins cause cell-free virolysis of HIV-1 Antimicrobial Agents and Chemotherapy. 58: 4249. DOI: 10.1128/AAC.03093-14  1
2013 Bastian AR, Contarino M, Bailey LD, Aneja R, Moreira DRM, Freedman K, McFadden K, Duffy C, Emileh A, Leslie G, Jacobson JM, Hoxie JA, Chaiken I. Interactions of peptide triazole thiols with Env gp120 induce irreversible breakdown and inactivation of HIV-1 virions Retrovirology. 10. PMID 24330857 DOI: 10.1186/1742-4690-10-153  1
2013 Li H, Aneja R, Chaiken I. Click chemistry in peptide-based drug design. Molecules (Basel, Switzerland). 18: 9797-817. PMID 23959192 DOI: 10.3390/molecules18089797  1
2013 Contarino M, Bastian AR, Kalyana Sundaram RV, McFadden K, Duffy C, Gangupomu V, Baker M, Abrams C, Chaiken I. Chimeric Cyanovirin-MPER recombinantly engineered proteins cause cell-free virolysis of HIV-1. Antimicrobial Agents and Chemotherapy. 57: 4743-50. PMID 23856780 DOI: 10.1128/AAC.00309-13  1
2013 Emileh A, Tuzer F, Yeh H, Umashankara M, Moreira DR, Lalonde JM, Bewley CA, Abrams CF, Chaiken IM. A model of peptide triazole entry inhibitor binding to HIV-1 gp120 and the mechanism of bridging sheet disruption. Biochemistry. 52: 2245-61. PMID 23470147 DOI: 10.1021/bi400166b  1
2013 Kamanna K, Aneja R, Duffy C, Kubinski P, Rodrigo Moreira D, Bailey LD, McFadden K, Schön A, Holmes A, Tuzer F, Contarino M, Freire E, Chaiken IM. Non-natural peptide triazole antagonists of HIV-1 envelope gp120. Chemmedchem. 8: 322-8. PMID 23239505 DOI: 10.1002/cmdc.201200422  0.64
2013 Freedman KJ, Bastian AR, Chaiken I, Kim MJ. Solid-state nanopore detection of protein complexes: Applications in healthcare and protein kinetics Small. 9: 750-759. PMID 23074081 DOI: 10.1002/smll.201201423  1
2013 Tuzer F, Madani N, Kamanna K, Zentner I, LaLonde J, Holmes A, Upton E, Rajagopal S, McFadden K, Contarino M, Sodroski J, Chaiken I. HIV-1 Env gp120 structural determinants for peptide triazole dual receptor site antagonism. Proteins. 81: 271-90. PMID 23011758 DOI: 10.1002/prot.24184  1
2012 McFadden K, Fletcher P, Rossi F, Kantharaju, Umashankara M, Pirrone V, Rajagopal S, Gopi H, Krebs FC, Martin-Garcia J, Shattock RJ, Chaiken I. Antiviral breadth and combination potential of peptide triazole HIV-1 entry inhibitors. Antimicrobial Agents and Chemotherapy. 56: 1073-80. PMID 22083481 DOI: 10.1128/AAC.05555-11  1
2012 Kubinski PL, Lowman AM, Duffy C, Kantharaju, Contarino MR, Chaiken I. Complexation hydrogels for stabilization of peptidic HIV-1 virucides 2012 38th Annual Northeast Bioengineering Conference, Nebec 2012. 422-423. DOI: 10.1109/NEBC.2012.6206921  1
2011 Ishino T, Economou NJ, McFadden K, Zaks-Zilberman M, Jost M, Baxter S, Contarino MR, Harrington AE, Loll PJ, Pasut G, Lievens S, Tavernier J, Chaiken I. A protein engineering approach differentiates the functional importance of carbohydrate moieties of interleukin-5 receptor α. Biochemistry. 50: 7546-56. PMID 21770429 DOI: 10.1021/bi2009135  1
2011 Bastian AR, Kantharaju, McFadden K, Duffy C, Rajagopal S, Contarino MR, Papazoglou E, Chaiken I. Cell-free HIV-1 virucidal action by modified peptide triazole inhibitors of Env gp120. Chemmedchem. 6: 1335-9, 1318. PMID 21714095 DOI: 10.1002/cmdc.201100177  1
2011 Mero A, Ishino T, Chaiken I, Veronese FM, Pasut G. Multivalent and flexible PEG-nitrilotriacetic acid derivatives for non-covalent protein pegylation Pharmaceutical Research. 28: 2412-2421. PMID 21611874 DOI: 10.1007/s11095-011-0468-8  1
2011 Gift SK, McFadden K, Zentner IJ, Rajagopal S, Zhang MY, Dimitrov DS, Chaiken IM. Monoclonal antibody m18 paratope leading to dual receptor antagonism of HIV-1 gp120. Biochemistry. 50: 2769-79. PMID 21417283 DOI: 10.1021/bi101161j  1
2011 Gift SK, Zentner IJ, Schön A, McFadden K, Umashankara M, Rajagopal S, Contarino M, Duffy C, Courter JR, Zhang MY, Gershoni JM, Cocklin S, Dimitrov DS, Smith AB, Freire E, ... Chaiken IM, et al. Conformational and structural features of HIV-1 gp120 underlying the dual receptor antagonism by cross-reactive neutralizing antibody m18. Biochemistry. 50: 2756-68. PMID 21351734 DOI: 10.1021/bi101160r  1
2010 Umashankara M, McFadden K, Zentner I, Schön A, Rajagopal S, Tuzer F, Kuriakose SA, Contarino M, Lalonde J, Freire E, Chaiken I. The active core in a triazole peptide dual-site antagonist of HIV-1 gp120 Chemmedchem. 5: 1871-1879. PMID 20677318 DOI: 10.1002/cmdc.201000222  1
2010 Lee HS, Contarino M, Umashankara M, Schön A, Freire E, Smith AB, Chaiken IM, Penn LS. Use of the quartz crystal microbalance to monitor ligand-induced conformational rearrangements in HIV-1 envelope protein gp120. Analytical and Bioanalytical Chemistry. 396: 1143-52. PMID 20016882 DOI: 10.1007/s00216-009-3313-8  1
2009 Gopi H, Cocklin S, Pirrone V, McFadden K, Tuzer F, Zentner I, Ajith S, Baxter S, Jawanda N, Krebs FC, Chaiken IM. Introducing metallocene into a triazole peptide conjugate reduces its off-rate and enhances its affinity and antiviral potency for HIV-1 gp120. Journal of Molecular Recognition : Jmr. 22: 169-74. PMID 18498083 DOI: 10.1002/jmr.892  1
2009 Contarino MR, Withey G, Chaiken I. Isotropic Display of Biomolecules on CNT-Arrayed Nanostructures Biosensing Using Nanomaterials. 39-65. DOI: 10.1002/9780470447734.ch2  1
2008 Cannon G, Yi Y, Ni H, Stoddard E, Scales DA, Van Ryk DI, Chaiken I, Malamud D, Weissman D. HIV envelope binding by macrophage-expressed gp340 promotes HIV-1 infection. Journal of Immunology (Baltimore, Md. : 1950). 181: 2065-70. PMID 18641344  1
2008 Ishino T, Harrington AE, Gopi H, Chaiken I. Structure-based rationale for interleukin 5 receptor antagonism Current Pharmaceutical Design. 14: 1231-1239. PMID 18473871 DOI: 10.2174/138161208784246144  1
2008 Kamat V, Donaldson JM, Kari C, Quadros MR, Lelkes PI, Chaiken I, Cocklin S, Williams JC, Papazoglou E, Rodeck U. Enhanced EGFR inhibition and distinct epitope recognition by EGFR antagonistic mAbs C225 and 425. Cancer Biology & Therapy. 7: 726-33. PMID 18424917 DOI: 10.4161/cbt.7.5.6097  1
2008 Gopi H, Umashankara M, Pirrone V, LaLonde J, Madani N, Tuzer F, Baxter S, Zentner I, Cocklin S, Jawanda N, Miller SR, Schön A, Klein JC, Freire E, Krebs FC, ... ... Chaiken I, et al. Structural determinants for affinity enhancement of a dual antagonist peptide entry inhibitor of human immunodeficiency virus type-1 Journal of Medicinal Chemistry. 51: 2638-2647. PMID 18402432 DOI: 10.1021/jm070814r  1
2008 Zaks-Zilberman M, Harrington AE, Ishino T, Chaiken IM. Interleukin-5 receptor subunit oligomerization and rearrangement revealed by fluorescence resonance energy transfer imaging. The Journal of Biological Chemistry. 283: 13398-406. PMID 18326494 DOI: 10.1074/jbc.M710230200  1
2008 Ishino T, Harrington AE, Zaks-Zilberman M, Scibek JJ, Chaiken I. Slow-dissociation effect of common signaling subunit beta c on IL5 and GM-CSF receptor assembly. Cytokine. 42: 179-90. PMID 18294864 DOI: 10.1016/j.cyto.2007.12.010  1
2008 Kamat V, Donaldson JM, Kari C, Quadros MRD, Lelkes PI, Chaiken I, Cocklin S, Williams JC, Papazoglou E, Rodeck U. Enhanced EGFR inhibition and distinct epitope recognition by EGFR antagonistic mAbs C225 and 425 Cancer Biology and Therapy. 7: 728-735.  1
2007 McFadden K, Cocklin S, Gopi H, Baxter S, Ajith S, Mahmood N, Shattock R, Chaiken I. A recombinant allosteric lectin antagonist of HIV-1 envelope gp120 interactions. Proteins. 67: 617-29. PMID 17348010 DOI: 10.1002/prot.21295  1
2007 Cocklin S, Gopi H, Querido B, Nimmagadda M, Kuriakose S, Cicala C, Ajith S, Baxter S, Arthos J, Martín-García J, Chaiken IM. Broad-spectrum anti-human immunodeficiency virus (HIV) potential of a peptide HIV type 1 entry inhibitor. Journal of Virology. 81: 3645-8. PMID 17251295 DOI: 10.1128/JVI.01778-06  1
2007 Bhattacharya M, Pillalamari U, Sarkhel S, Ishino T, Urbina C, Jameson B, Chaiken I. Recruitment pharmacophore for interleukin 5 receptor α antagonism Biopolymers - Peptide Science Section. 88: 83-93. PMID 17041908 DOI: 10.1002/bip.20612  1
2006 Yang X, Lipchina I, Cocklin S, Chaiken I, Sodroski J. Antibody binding is a dominant determinant of the efficiency of human immunodeficiency virus type 1 neutralization. Journal of Virology. 80: 11404-8. PMID 16956933 DOI: 10.1128/JVI.01102-06  1
2006 Gopi HN, Tirupula KC, Baxter S, Ajith S, Chaiken IM. Click chemistry on azidoproline: high-affinity dual antagonist for HIV-1 envelope glycoprotein gp120. Chemmedchem. 1: 54-7. PMID 16892335 DOI: 10.1002/cmdc.200500037  1
2006 Baxter SC, Panarello D, Ajith S, Bhattacharya M, Chaiken IM. Recombinant-protein production in insect cells utilizing a hollow-fibre bioreactor. Biotechnology and Applied Biochemistry. 45: 167-72. PMID 16872272 DOI: 10.1042/BA20060074  1
2006 Contarino MR, Sergi M, Harrington AE, Lazareck A, Xu J, Chaiken I. Modular, self-assembling peptide linkers for stable and regenerable carbon nanotube biosensor interfaces. Journal of Molecular Recognition : Jmr. 19: 363-71. PMID 16775846 DOI: 10.1002/jmr.783  1
2006 Cocklin S, Jost M, Robertson NM, Weeks SD, Weber HW, Young E, Seal S, Zhang C, Mosser E, Loll PJ, Saunders AJ, Rest RF, Chaiken IM. Real-time monitoring of the membrane-binding and insertion properties of the cholesterol-dependent cytolysin anthrolysin O from Bacillus anthracis. Journal of Molecular Recognition : Jmr. 19: 354-62. PMID 16775845 DOI: 10.1002/jmr.784  1
2006 Ishino T, Pillalamarri U, Panarello D, Bhattacharya M, Urbina C, Horvat S, Sarkhel S, Jameson B, Chaiken I. Asymmetric usage of antagonist charged residues drives interleukin-5 receptor recruitment but is insufficient for receptor activation Biochemistry. 45: 1106-1115. PMID 16430207 DOI: 10.1021/bi0518038  1
2005 Ishino T, Robertson N, Chaiken I. Cytokine Recognition by Human Interleukin 5 Receptor Vitamins and Hormones. 71: 321-344. PMID 16112273 DOI: 10.1016/S0083-6729(05)71011-6  1
2005 Martín-García J, Cocklin S, Chaiken IM, González-Scarano F. Interaction with CD4 and antibodies to CD4-induced epitopes of the envelope gp120 from a microglial cell-adapted human immunodeficiency virus type 1 isolate. Journal of Virology. 79: 6703-13. PMID 15890908 DOI: 10.1128/JVI.79.11.6703-6713.2005  1
2005 Ishino T, Urbina C, Bhattacharya M, Panarello D, Chaiken I. Receptor epitope usage by an interleukin-5 mimetic peptide Journal of Biological Chemistry. 280: 22951-22961. PMID 15826943 DOI: 10.1074/jbc.M502341200  1
2005 Colleluori DM, Tien D, Kang F, Pagliei T, Kuss R, McCormick T, Watson K, McFadden K, Chaiken I, Buckheit RW, Romano JW. Expression, purification, and characterization of recombinant cyanovirin-N for vaginal anti-HIV microbicide development. Protein Expression and Purification. 39: 229-36. PMID 15642474 DOI: 10.1016/j.pep.2004.10.009  1
2005 McGovern JP, Shih WY, Shih WH, Sergi M, Chaiken I. Real-time salmonella detection using lead zirconate titanate-titanium microcantilevers Materials Research Society Symposium Proceedings. 845: 83-88.  1
2004 Sergi M, Zurawski J, Cocklin S, Chaiken I. Proteins, recognition networks and developing interfaces for macromolecular biosensing Journal of Molecular Recognition. 17: 198-208. PMID 15137030 DOI: 10.1002/jmr.671  1
2004 Si Z, Madani N, Cox JM, Chruma JJ, Klein JC, Schön A, Phan N, Wang L, Biorn AC, Cocklin S, Chaiken I, Freire E, Smith AB, Sodroski JG. Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins. Proceedings of the National Academy of Sciences of the United States of America. 101: 5036-41. PMID 15051887 DOI: 10.1073/pnas.0307953101  1
2004 Ruchala P, Varadi G, Ishino T, Scibek J, Bhattacharya M, Urbina C, Van Ryk D, Uings I, Chaiken I. Cyclic Peptide Interleukin 5 Antagonists Mimic CD Turn Recognition Epitope for Receptor α Biopolymers. 73: 556-568. PMID 15048779 DOI: 10.1002/bip.20001  1
2004 Biorn AC, Cocklin S, Madani N, Si Z, Ivanovic T, Samanen J, Van Ryk DI, Pantophlet R, Burton DR, Freire E, Sodroski J, Chaiken IM. Mode of action for linear peptide inhibitors of HIV-1 gp120 interactions. Biochemistry. 43: 1928-38. PMID 14967033 DOI: 10.1021/bi035088i  1
2004 Leavitt SA, SchOn A, Klein JC, Manjappara U, Chaiken IM, Freire E. Interactions of HIV-1 proteins gp120 and Nef with cellular partners define a novel allosteric paradigm. Current Protein & Peptide Science. 5: 1-8. PMID 14965316 DOI: 10.2174/1389203043486955  1
2004 Ishino T, Pasut G, Scibek J, Chaiken I. Kinetic Interaction Analysis of Human Interleukin 5 Receptor α Mutants Reveals a Unique Binding Topology and Charge Distribution for Cytokine Recognition Journal of Biological Chemistry. 279: 9547-9556. PMID 14662768 DOI: 10.1074/jbc.M309327200  1
2004 Wu SJ, Chaiken I. Biosensor analysis of receptor-ligand interactions Methods in Molecular Biology (Clifton, N.J.). 249: 93-110. PMID 14573894  1
2004 Contarino MR, Kamat V, Keough E, Babu NS, Sergi M, Ishino T, Papazoglou E, Chaiken IM, Tyagi S, Pourrezaei K. Bio-nano-optics for cellular investigations Progress in Biomedical Optics and Imaging - Proceedings of Spie. 5588: 31-40. DOI: 10.1117/12.571248  1
2003 Wu Z, Van Ryk D, Davis C, Abrams WR, Chaiken I, Magnani J, Malamud D. Salivary agglutinin inhibits HIV type 1 infectivity through interaction with viral glycoprotein 120 Aids Research and Human Retroviruses. 19: 201-209. PMID 12689412 DOI: 10.1089/088922203763315704  1
2002 Kwong PD, Doyle ML, Casper DJ, Cicala C, Leavitt SA, Majeed S, Steenbeke TD, Venturi M, Chaiken I, Fung M, Katinger H, Parren PWIH, Robinson J, Van Ryk D, Wang L, et al. HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites Nature. 420: 678-682. PMID 12478295 DOI: 10.1038/nature01188  1
2002 Smith AB, Savinov SN, Manjappara UV, Chaiken IM. Peptide-small molecule hybrids via orthogonal deprotection-chemoselective conjugation to cysteine-anchored scaffolds. A model study. Organic Letters. 4: 4041-4. PMID 12423081 DOI: 10.1021/ol026736d  1
2002 Monfardini C, Canziani G, Plugariu C, Kieber-Emmons T, Godillot AP, Kwah J, Bajgier J, Chaiken I, Williams WV. Structure-based design of mimetics for granulocyte-macrophage colony stimulating factor (GM-CSF) Current Pharmaceutical Design. 8: 2185-2199. PMID 12369862 DOI: 10.2174/1381612023393198  1
2002 Scibek JJ, Evergren E, Zahn S, Canziani GA, Van Ryk D, Chaiken IM. Biosensor analysis of dynamics of interleukin 5 receptor subunit beta(c) interaction with IL5:IL5R(alpha) complexes. Analytical Biochemistry. 307: 258-65. PMID 12202242 DOI: 10.1016/S0003-2697(02)00043-X  1
2002 Dowd CS, Leavitt S, Babcock G, Godillot AP, Van Ryk D, Canziani GA, Sodroski J, Freire E, Chaiken IM. Beta-turn Phe in HIV-1 Env binding site of CD4 and CD4 mimetic miniprotein enhances Env binding affinity but is not required for activation of co-receptor/17b site. Biochemistry. 41: 7038-46. PMID 12033937 DOI: 10.1021/bi012168i  1
2002 Li C, Plugariu CG, Bajgier J, White JR, Liefer KM, Wu SJ, Chaiken I. Coiled coil miniprotein randomization on phage leads to charge pattern mimicry of the receptor recognition determinant of interleukin 5 Journal of Molecular Recognition. 15: 33-43. PMID 11870920 DOI: 10.1002/jmr.558  1
2001 Chaiken I. Revealing and utilizing receptor recognition mechanisms in a high-throughput world Journal of Cellular Biochemistry. 84: 126-135. PMID 11842438 DOI: 10.1002/jcb.10079  1
2001 Li C, Dowd CS, Zhang W, Chaiken IM. Phage randomization in a charybdotoxin scaffold leads to CD4-mimetic recognition motifs that bind HIV-1 envelope through non-aromatic sequences. The Journal of Peptide Research : Official Journal of the American Peptide Society. 57: 507-18. PMID 11437954 DOI: 10.1046/j.1397-002X.2001.00876.x  1
2001 Dowd CS, Zhang W, Li C, Chaiken IM. From receptor recognition mechanisms to bioinspired mimetic antagonists in HIV-1/cell docking. Journal of Chromatography. B, Biomedical Sciences and Applications. 753: 327-35. PMID 11334348 DOI: 10.1016/S0378-4347(00)00567-3  1
2001 Zhang W, Godillot AP, Wyatt R, Sodroski J, Chaiken I. Antibody 17b binding at the coreceptor site weakens the kinetics of the interaction of envelope glycoprotein gp120 with CD4 Biochemistry. 40: 1662-1670. PMID 11327825 DOI: 10.1021/bi001397m  1
2001 Zabeau L, Van der Heyden J, Broekaert D, Verhee A, Vandekerckhove J, Wu SJ, Chaiken I, Heinrich P, Behrmann I, Tavernier J. Neutralizing monoclonal antibodies can potentiate IL-5 signaling European Journal of Immunology. 31: 1087-1097. PMID 11298333 DOI: 10.1002/1521-4141(200104)31:4<1087::AID-IMMU1087>3.0.CO;2-Q  1
2000 Plugariu CG, Wu SJ, Zhang W, Chaiken I. Multisite mutagenesis of interleukin 5 differentiates sites for receptor recognition and receptor activation Biochemistry. 39: 14939-14949. PMID 11101310 DOI: 10.1021/bi001467p  1
2000 O'Keefe BR, Shenoy SR, Xie D, Zhang W, Muschik JM, Currens MJ, Chaiken I, Boyd MR. Analysis of the interaction between the HIV-inactivating protein cyanovirin-N and soluble forms of the envelope glycoproteins gp120 and gp41. Molecular Pharmacology. 58: 982-92. PMID 11040045  1
2000 Zahn S, Godillot P, Yoshimura A, Chaiken I. IL-5-induced JAB-JAK2 interaction Cytokine. 12: 1299-1306. PMID 10975987 DOI: 10.1006/cyto.2000.0718  1
2000 Wilchek M, Chaiken I. An overview of affinity chromatography Methods in Molecular Biology (Clifton, N.J.). 147: 1-6. PMID 10857080  1
2000 Sheng N, Fairbanks MB, Heinrikson RL, Canziani G, Chaiken IM, Mosser DM, Zhang H, Colman RW. Cleaved high molecular weight kininogen binds directly to the integrin CD11b/CD18 (Mac-1) and blocks adhesion to fibrinogen and ICAM-1. Blood. 95: 3788-95. PMID 10845911  1
2000 Wu SJ, Tambyraja R, Zhang W, Zahn S, Godillot AP, Chaiken I. Epitope randomization redefines the functional role of glutamic acid 110 in interleukin-5 receptor activation Journal of Biological Chemistry. 275: 7351-7358. PMID 10702307 DOI: 10.1074/jbc.275.10.7351  1
1999 Canziani G, Zhang W, Cines D, Rux A, Willis S, Cohen G, Eisenberg R, Chaiken I. Exploring biomolecular recognition using optical biosensors Methods: a Companion to Methods in Enzymology. 19: 253-269. PMID 10527730 DOI: 10.1006/meth.1999.0855  1
1999 Bdeir K, Cane W, Canziani G, Chaiken I, Weisel J, Koschinsky ML, Lawn RM, Bannerman PG, Sachais BS, Kuo A, Hancock MA, Tomaszewski J, Raghunath PN, Ganz T, Higazi AAR, et al. Defensin promotes the binding of lipoprotein(a) to vascular matrix Blood. 94: 2007-2019. PMID 10477730  1
1999 Zhang W, Canziani G, Plugariu C, Wyatt R, Sodroski J, Sweet R, Kwong P, Hendrickson W, Chaiken I. Conformational changes of gp120 in epitopes near the CCR5 binding site are induced by CD4 and a CD4 miniprotein mimetic Biochemistry. 38: 9405-9416. PMID 10413516 DOI: 10.1021/bi990654o  1
1999 Wu SJ, Li J, Tsui P, Cook R, Zhang W, Hu Y, Canziani G, Chaiken I. Randomization of the receptor α chain recruitment epitope reveals a functional interleukin-5 with charge depletion in the CD loop Journal of Biological Chemistry. 274: 20479-20488. PMID 10400676 DOI: 10.1074/jbc.274.29.20479  1
1999 Hoffman TL, LaBranche CC, Zhang W, Canziani G, Robinson J, Chaiken I, Hoxie JA, Doms RW. Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein. Proceedings of the National Academy of Sciences of the United States of America. 96: 6359-64. PMID 10339592 DOI: 10.1073/pnas.96.11.6359  1
1998 Shan H, Goldman J, Cunto G, Manuppello J, Chaiken I, Cines DB, Silberstein LE. Heterogeneity of anti-phospholipid and anti-endothelial cell antibodies Journal of Autoimmunity. 11: 651-660. PMID 9878087 DOI: 10.1006/jaut.1998.0242  1
1998 Monfardini C, Ramamoorthy M, Rosenbaum H, Fang Q, Godillot PA, Canziani G, Chaiken IM, Williams WV. Construction and binding kinetics of a soluble granulocyte-macrophage colony-stimulating factor receptor alpha-chain-Fc fusion protein. The Journal of Biological Chemistry. 273: 7657-67. PMID 9516471 DOI: 10.1074/jbc.273.13.7657  1
1998 Fan Z, Larson PJ, Bognacki J, Raghunath PN, Tomaszewski JE, Kuo A, Canziani G, Chaiken I, Cines DB, Higazi AAR. Tissue factor regulates plasminogen binding and activation Blood. 91: 1987-1998. PMID 9490681  1
1998 Zahn S, Meh S, Chaiken I. Il-5 induces both phosphorylation and dephosphorylation in tf-1.28 cells Faseb Journal. 12: A1464.  1
1998 Zhang W, Canziani G, Wyatt R, Sodroski J, Sweet R, Kwong P, Hendrkkson W, Chaiken I. Probing ligand-induced conformational isomerization in the viral envelope glycoprotein gp120 by optical biosensor kinetic analysis Faseb Journal. 12: A1442.  1
1998 Wu GSJ, Li J, Tsui P, Cook R, Hu Y, Canziani G, Chaiken I. Functional phage display of single chain interleukin Faseb Journal. 12: A1462.  1
1998 Ramamoorthy M, Monfardini C, Rosenbaum H, Godillot PA, Canziani G, Chaiken I, Williams WV. GM-CSF receptor binding kinetics and bioactivity Faseb Journal. 12: A1052.  1
1997 Li J, Cook R, Doyle ML, Hensley P, McNulty DE, Chaiken I. Monomeric isomers of human interleukin 5 show that 1:1 receptor recruitment is sufficient for function Proceedings of the National Academy of Sciences of the United States of America. 94: 6694-6699. PMID 9192627 DOI: 10.1073/pnas.94.13.6694  1
1997 Myszka DG, Morton TA, Doyle ML, Chaiken IM. Kinetic analysis of a protein antigen-antibody interaction limited by mass transport on an optical biosensor. Biophysical Chemistry. 64: 127-37. PMID 9127943 DOI: 10.1016/S0301-4622(96)02230-2  1
1997 Sheng N, Fairbanks M, Heinrikson R, Canziani G, Chaiken I, Mosser D, Colman RW. The integrin CD11b/cd18 (MAC-1) is a major cell receptor for high molecular weight kininogen (HK) Faseb Journal. 11: A919.  1
1996 Li J, Cook R, Chaiken I. Interleukin 5 Interactions with Soluble and Cell Surface Forms of its Receptor Journal of Molecular Recognition. 9: 347-355. PMID 9174908  1
1996 Chaiken IM, Williams WV. Identifying structure-function relationships in four-helix bundle cytokines: towards de novo mimetics design. Trends in Biotechnology. 14: 369-75. PMID 8987635 DOI: 10.1016/0167-7799(96)10050-0  1
1996 Wu H, Myszka DG, Tendian SW, Brouillette CG, Sweet RW, Chaiken IM, Hendrickson WA. Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding. Proceedings of the National Academy of Sciences of the United States of America. 93: 15030-5. PMID 8986758 DOI: 10.1073/pnas.93.26.15030  1
1996 Li J, Cook R, Chaiken I. Mutants of single chain interleukin 5 show asymmetric recruitment of receptor α and β(c) subunits Journal of Biological Chemistry. 271: 31729-31734. PMID 8940197 DOI: 10.1074/jbc.271.49.31729  1
1996 Doyle ML, Myszka DG, Chaiken IM. Molecular interaction analysis in ligand design using mass transport, kinetic and thermodynamic methods. Journal of Molecular Recognition : Jmr. 9: 65-74. PMID 8877796 DOI: 10.1002/(SICI)1099-1352(199603)9:2<65::AID-JMR245>3.0.CO;2-B  1
1996 Miceli R, Myszka D, Mao J, Sathe G, Chaiken I. The coiled coil stem loop miniprotein as a presentation scaffold Drug Design and Discovery. 13: 95-105. PMID 8874047  1
1996 It J, Cook R, Dede K, Chaiken I. Single chain human interleukin 5 and its asymmetric mutagenesis for mapping receptor binding sites Faseb Journal. 10: A1376. DOI: 10.1074/jbc.271.4.1817  1
1996 Chaiken I, Myszka D, Morton T. New Opportunities for Using Immobilized Ligands to Characterize Macromolecular Recognition and Design Recognition Molecules Advances in Molecular and Cell Biology. 15: 553-568. DOI: 10.1016/S1569-2558(08)60136-8  1
1996 Brouillette CG, Tendian SW, Heard BC, Dunleavy D, Shorter AL, Myszka DG, Chaiken IM. Storage stability of the solution formulation of sCD4 determined by DSC in comparison with two functional assays Journal of Thermal Analysis. 47: 1597-1609.  1
1995 Ames RS, Tornetta MA, McMillan LJ, Kaiser KF, Holmes SD, Appelbaum E, Cusimano DM, Theisen TW, Gross MS, Jones CS, Silverman C, Porter TG, Cook RM, Bennett D, Chaiken IM. Neutralizing murine monoclonal antibodies to human IL-5 isolated from hybridomas and a filamentous phage Fab display library Journal of Immunology. 154: 6355-6364. PMID 7759873  1
1995 Tendian SW, Myszka DG, Sweet RW, Chaiken IM, Brouillette CG. Interdomain communication of T-cell CD4 studied by absorbance and fluorescence difference spectroscopy measurements of urea-induced unfolding. Biochemistry. 34: 6464-74. PMID 7756278  1
1995 Morton TA, Myszka DG, Chaiken IM. Interpreting complex binding kinetics from optical biosensors: a comparison of analysis by linearization, the integrated rate equation, and numerical integration. Analytical Biochemistry. 227: 176-85. PMID 7668379 DOI: 10.1006/abio.1995.1268  1
1994 Myszka DG, Chaiken IM. Design and characterization of an intramolecular antiparallel coiled coil peptide. Biochemistry. 33: 2363-72. PMID 8117695  1
1994 Morton TA, Bennett DB, Appelbaum ER, Cusimano DM, Johanson KO, Matico RE, Young PR, Doyle M, Chaiken IM. Analysis of the interaction between human interleukin-5 and the soluble domain of its receptor using a surface plasmon resonance biosensor. Journal of Molecular Recognition : Jmr. 7: 47-55. PMID 7986567 DOI: 10.1002/jmr.300070107  1
1993 Graddis TJ, Myszka DG, Chaiken IM. Controlled formation of model homo- and heterodimer coiled coil polypeptides. Biochemistry. 32: 12664-71. PMID 8251485 DOI: 10.1021/bi00210a015  1
1992 Tropsha A, Kizer JS, Chaiken IM. Making sense from antisense: a review of experimental data and developing ideas on sense--antisense peptide recognition. Journal of Molecular Recognition : Jmr. 5: 43-54. PMID 1472380 DOI: 10.1002/jmr.300050202  1
1990 Caliceti P, Schiavon O, Veronese FM, Chaiken IM. Effects of monomethoxypoly(ethylene glycol) modification of ribonuclease on antibody recognition, substrate accessibility and conformational stability. Journal of Molecular Recognition : Jmr. 3: 89-93. PMID 2361062 DOI: 10.1002/jmr.300030206  1
1989 Chaiken IM. Bioaffinity chromatography: synergy between interactive chromatography and molecular recognition for the separation and analysis of macromolecules. Journal of Chromatography. 488: 145-60. PMID 2715281 DOI: 10.1016/S0378-4347(00)82944-8  1
1989 Fassina G, Chaiken IM. Sequence simplification and the intra- and intermolecular self-recognition properties of vasopressin/neurophysin biosynthetic precursor. Journal of Molecular Recognition : Jmr. 1: 158-65. PMID 2631863 DOI: 10.1002/jmr.300010403  1
1989 Fassina G, Zamai M, Brigham-Burke M, Chaiken IM. Recognition properties of antisense peptides to Arg8-vasopressin/bovine neurophysin II biosynthetic precursor sequences. Biochemistry. 28: 8811-8. PMID 2605222  1
1989 Shai Y, Brunck TK, Chaiken IM. Antisense peptide recognition of sense peptides: sequence simplification and evaluation of forces underlying the interaction. Biochemistry. 28: 8804-11. PMID 2605221  1
1988 Fassina G, Chaiken IM. Structural requirements of peptide hormone binding for peptide-potentiated self-association of bovine neurophysin II. The Journal of Biological Chemistry. 263: 13539-43. PMID 3417672  1
1988 Ando S, Murthy AS, Eipper BA, Chaiken IM. Effect of neurophysin on enzymatic maturation of oxytocin from its precursor. The Journal of Biological Chemistry. 263: 769-75. PMID 3275658  1
1987 Ando S, McPhie P, Chaiken IM. Sequence redesign and the assembly mechanism of the oxytocin/bovine neurophysin I biosynthetic precursor. The Journal of Biological Chemistry. 262: 12962-9. PMID 3654597  1
1987 Shai Y, Flashner M, Chaiken IM. Anti-sense peptide recognition of sense peptides: direct quantitative characterization with the ribonuclease S-peptide system using analytical high-performance affinity chromatography. Biochemistry. 26: 669-75. PMID 3567139  1
1987 Caliceti P, Fassina G, Chaiken IM. Molecular diagnostics using analytical immuno high performance liquid affinity chromatography. Applied Biochemistry and Biotechnology. 16: 119-28. PMID 3504125 DOI: 10.1007/BF02798361  1
1987 Abercrombie DM, Chaiken IM. Oxytocin and vasopressin: photoaffinity labeling of neurophysins, secretory granule hormone-binding proteins. Pharmacology & Therapeutics. 33: 209-19. PMID 3310032 DOI: 10.1016/0163-7258(87)90065-9  1
1987 Fassina G, Chaiken IM. Analytical high-performance affinity chromatography. Advances in Chromatography. 27: 247-97. PMID 3307323  1
1987 Chaiken IM, Ando S, Fassina G. Enzymatic synthesis of processing and the formation of biologically active peptides and proteins Advances in the Biosciences. 65: 141-150.  1
1986 Watkins WB, Choy VJ, Chaiken IM, Spiess J. Isolation and sequence analysis of oxytocin from the sheep corpus luteum. Neuropeptides. 7: 87-95. PMID 3951682 DOI: 10.1016/0143-4179(86)90083-1  1
1986 Swaisgood HE, Chaiken IM. Analytical high-performance affinity chromatography: evaluation by studies of neurophysin self-association and neurophysin-peptide hormone interaction using glass matrices. Biochemistry. 25: 4148-55. PMID 3741847  1
1986 Fassina G, Swaisgood HE, Chaiken IM. Quantitative high-performance affinity chromatography: evaluation of use for analyzing peptide and protein interactions. Journal of Chromatography. 376: 87-93. PMID 3711200 DOI: 10.1016/S0378-4347(00)80825-7  1
1986 Chaiken IM. Analytical affinity chromatography in studies of molecular recognition in biology: a review. Journal of Chromatography. 376: 11-32. PMID 3519631 DOI: 10.1016/S0378-4347(00)80821-X  1
1986 Chaiken IM, Kanmera T, Sequeira RP. Folding and enzymatic processing of precursors of biologically active peptides and proteins. Nida Research Monograph. 70: 3-20. PMID 3093880  1
1985 Swaisgood HE, Chaiken IM. Quantitative affinity high-performance liquid chromatography of neuroendocrine polypeptides using porous and non-porous glass derivatives. Journal of Chromatography. 327: 193-204. PMID 4030955 DOI: 10.1016/S0021-9673(01)81649-6  1
1985 Kanmera T, Chaiken IM. Pituitary enzyme conversion of putative synthetic oxytocin precursor intermediates. The Journal of Biological Chemistry. 260: 10118-24. PMID 4019503  1
1985 Kanmera T, Chaiken IM. Molecular properties of the oxytocin/bovine neurophysin biosynthetic precursor. Studies using a semisynthetic precursor. The Journal of Biological Chemistry. 260: 8474-82. PMID 4008499  1
1985 Corigliano-Murphy MA, Xun LA, Ponnamperuma C, Dalzoppo D, Fontana A, Kanmera T, Chaiken IM. Synthesis and properties of an all-D model ribonuclease S-peptide. International Journal of Peptide and Protein Research. 25: 225-31. PMID 3997353  1
1985 Taylor HC, Komoriya A, Chaiken IM. Crystallographic structure of an active, sequence-engineered ribonuclease. Proceedings of the National Academy of Sciences of the United States of America. 82: 6423-6. PMID 3863103  1
1985 Shoemaker KR, Kim PS, Brems DN, Marqusee S, York EJ, Chaiken IM, Stewart JM, Baldwin RL. Nature of the charged-group effect on the stability of the C-peptide helix. Proceedings of the National Academy of Sciences of the United States of America. 82: 2349-53. PMID 3857585 DOI: 10.1073/pnas.82.8.2349  1
1985 Vita C, Fontana A, Chaiken IM. Folding of thermolysin fragments. Correlation between conformational stability and antigenicity of carboxyl-terminal fragments. European Journal of Biochemistry / Febs. 151: 191-6. PMID 2411552  1
1984 Chaiken IM, Miller TH, Sequeira RP, Kanmera T. High-performance liquid chromatographic mapping and structural characterization of neurophysin isoforms. Analytical Biochemistry. 143: 215-25. PMID 6532238 DOI: 10.1016/0003-2697(84)90656-0  1
1984 Chaiken IM, Kanmera T, Sequiera RP, Swaisgood HE. High-performance liquid chromatography and studies of neurophysin-neurohypophysial hormone pathways. Journal of Chromatography. 336: 63-71. PMID 6526926 DOI: 10.1016/S0378-4347(00)85130-0  1
1984 Abercrombie DM, Kanmera T, Angal S, Tamaoki H, Chaiken IM. Cooperative interactions in neurophysin-neuropeptide hormone complexes. Analytical affinity chromatography of native and covalently-modified neurophysins. International Journal of Peptide and Protein Research. 24: 218-32. PMID 6500806  1
1984 Eisenstein E, Osborne JC, Chaiken IM, Hensley P. Purification and characterization of ornithine transcarbamoylase from Saccharomyces cerevisiae. The Journal of Biological Chemistry. 259: 5139-45. PMID 6370999  1
1984 Hough CJ, Chaiken IM. Characterization of the size and 5' cap of messenger RNA encoding neurophysin precursors. Nucleic Acids Research. 12: 4397-410. PMID 6145145 DOI: 10.1093/nar/12.10.4397  1
1984 Kannera T, Chaiken IM. Semisynthesis and molecular properties of a neurohypophyseal hormone/neurophysin biosynthetic precursor analog Federation Proceedings. 43: no. 285.  1
1984 Sequeira RP, Chaiken IM. Molecular characterization of oxytocin, vasopressin and neurophysins in the ovary Federation Proceedings. 43: no. 3674.  1
1983 Kanmera T, Homandberg GA, Komoriya A, Chaiken IM. Minimum information content and formation of interacting ribonuclease fragment complexes. International Journal of Peptide and Protein Research. 21: 74-83. PMID 6826284  1
1983 Fontana A, Vita C, Chaiken IM. Domain characteristics of the carboxyl-terminal fragment 206-316 of thermolysin. Biopolymers. 22: 69-78. PMID 6673774 DOI: 10.1002/bip.360220112  1
1983 Chaiken IM. Neurophysin-neuropeptide hormone complexes: biosynthetic origin and noncovalent interactions. Biopolymers. 22: 355-62. PMID 6673764 DOI: 10.1002/bip.360220146  1
1983 Chaiken IM, Tamaoki H, Brownstein MJ, Gainer H. Onset of neurophysin self-association upon neurophysin/neuropeptide hormone precursor biosynthesis. Febs Letters. 164: 361-5. PMID 6653793 DOI: 10.1016/0014-5793(83)80317-2  1
1983 Chaudhry GR, Chaiken IM, MacGregor CH. An activity from Escherichia coli membranes responsible for the modification of nitrate reductase to its precursor form. The Journal of Biological Chemistry. 258: 5828-33. PMID 6343396  1
1982 Chaiken IM, Komoriya A, Ohno M, Widmer F. Use of enzymes in peptide synthesis. Applied Biochemistry and Biotechnology. 7: 385-99. PMID 24234364 DOI: 10.1007/BF02798320  1
1982 Abercrombie DM, Hough CJ, Seeman JR, Brownstein MJ, Gainer H, Russell JT, Chaiken IM. Use of reverse-phase high-performance liquid chromatography in structural studies of neurophysins, photolabeled derivatives, and biosynthetic precursors. Analytical Biochemistry. 125: 395-405. PMID 7181098 DOI: 10.1016/0003-2697(82)90021-5  1
1982 Abercrombie DM, Angal S, Sequeira RP, Chaiken IM. Effects of limited tryptic proteolysis of bovine neurophysins on molecular properties of hormone binding, self-association, and antigenicity. Biochemistry. 21: 6458-65. PMID 7150567  1
1982 Angal S, Chaiken IM. Interdependence of neurophysin self-association and neuropeptide hormone binding as expressed by quantitative affinity chromatography. Biochemistry. 21: 1574-80. PMID 7082636  1
1982 Abercrombie DM, McCormick WM, Chaiken IM. Photoaffinity labeling of the hormone binding site of neurophysin. The Journal of Biological Chemistry. 257: 2274-81. PMID 7061422  1
1982 Homandberg GA, Komoriya A, Chaiken IM. Enzymatic condensation of nonassociated peptide fragments using a molecular trap. Biochemistry. 21: 3385-9. PMID 7052121  1
1982 Komoriya A, Chaiken IM. Sequence modeling using semisynthetic ribonuclease S. The Journal of Biological Chemistry. 257: 2599-604. PMID 6277908  1
1982 Vita C, Fontana A, Chaiken IM. Domain characteristics of the carboxyl-terminal fragment 206-316 of thermolysin: immunochemical studies. Biochemistry. 21: 2016-22. PMID 6178430  1
1981 Taylor HC, Richardson DC, Richardson JS, Wlodawer A, Komoriya A, Chaikes IM. "Active" conformation of an inactive semi-synthetic ribonuclease-S. Journal of Molecular Biology. 149: 313-7. PMID 7310884 DOI: 10.1016/0022-2836(81)90305-3  1
1981 Chaiken IM. Semisynthetic peptides and proteins. Crc Critical Reviews in Biochemistry. 11: 255-301. PMID 7030620  1
1981 Burns PF, Campagnoni CW, Chaiken IM, Campagnoni AT. Interactions of free and immobilized myelin basic protein with anionic detergents. Biochemistry. 20: 2463-9. PMID 6165382  1
1980 Chaiken IM, Hough CJ. Mapping and isolation of large peptide fragments from bovine neurophysins and biosynthetic neurophysin-containing species by high-performance liquid chromatography. Analytical Biochemistry. 107: 11-6. PMID 7435946  1
1980 Homandberg GA, Chaiken IM. Trypsin-catalyzed conversion of staphylococcal nuclease-T fragment complexes to covalent forms. The Journal of Biological Chemistry. 255: 4903-9. PMID 7372615  1
1980 Komoriya A, Homandberg GA, Chaiken IM. Enzyme-catalyzed formation of semisynthetic staphylococcal nuclease using a new synthetic fragment, [48-glycine]synthetic-(6-49). International Journal of Peptide and Protein Research. 16: 433-9. PMID 7216618  1
1980 Hough CJ, Hargrave PA, Chaiken IM. On the biosynthetic origin of neurophysin-neurohypophyseal peptide hormone complexes European Journal of Cell Biology. 22: 790-791.  1
1979 Chaiken IM. Preparative and analytical affinity chromatography of neurophysins on methionyl-tyrosyl-phenylalanyl-aminohexyl-agarose. Analytical Biochemistry. 97: 302-8. PMID 525794 DOI: 10.1016/0003-2697(79)90076-9  1
1979 Giudice LC, Chaiken IM. Cell-free biosynthesis of different high molecular weight forms of bovine neurophysins I and II coded by hypothalamic mRNA. The Journal of Biological Chemistry. 254: 11767-70. PMID 500672  1
1979 Chaiken IM. Quantitative uses of affinity chromatography. Analytical Biochemistry. 97: 1-10. PMID 484830 DOI: 10.1016/0003-2697(79)90319-1  1
1979 Eilat D, Chaiken IM, McCormick WM. Expression of multivalency in the affinity chromatography of antibodies. Appendix: Derivation and evaluation of equations for independent bivalent interacting systems in quantitative affinity chromatography. Biochemistry. 18: 790-5. PMID 420816  1
1979 Giudice LC, Chaiken IM. Immunological and chemical identification of a neurophysin-containing protein coded by messenger RNA from bovine hypothalamus. Proceedings of the National Academy of Sciences of the United States of America. 76: 3800-4. PMID 291040  1
1979 Vita C, Fontana A, Seeman JR, Chaiken IM. Conformational and immunochemical analysis of the cyanogen bromide fragments of thermolysin. Biochemistry. 18: 3023-31. PMID 111708  1
1979 Veronese FM, Bevilacqua R, Chaiken IM. Drug-protein interactions: evaluation of the binding of antipsychotic drugs to glutamate dehydrogenase by quantitative affinity chromatography. Molecular Pharmacology. 15: 313-21. PMID 38392  1
1978 Klausner YS, McCormick WM, Chaiken IM. Design of a photoaffinity label for the hormone binding site of neurophysin. International Journal of Peptide and Protein Research. 11: 83-90. PMID 204588  1
1978 Chaiken IM, Komoriya A. Protein semisynthesis Trends in Biochemical Sciences. 3: 269-271. DOI: 10.1016/S0968-0004(78)95895-4  1
1977 Taylor HC, Chaiken IM. Active site ligand binding by an inactive ribonuclease S analogue. A quantitative affinity chromatographic study. The Journal of Biological Chemistry. 252: 6991-4. PMID 903349  1
1977 Chaiken IM, Taylor HC, Ammon HL. Crystal properties of (des 16-20) semisynthetic sequence variants of ribonuclease S'. The Journal of Biological Chemistry. 252: 5599-601. PMID 885867  1
1977 Fischer EA, Curd JG, Chaiken IM. Preparation of biologically active conjugates of bovine neurophysins and other polypeptides with multi-(poly-D,L-alanyl)--poly-L-lysine and their use to elicit antibodies. Immunochemistry. 14: 595-602. PMID 413789 DOI: 10.1016/0019-2791(77)90155-0  1
1976 Diliberto EJ, Axelrod J, Chaiken IM. The effects of ligands on enzymic carboxyl-methylation of neurophysins. Biochemical and Biophysical Research Communications. 73: 1063-7. PMID 15625882 DOI: 10.1016/0006-291X(76)90231-X  1
1976 Chaiken IM, Taylor HC. Analysis of ribonuclease-nucleotide interactions by quantitative affinity chromatography. The Journal of Biological Chemistry. 251: 2044-8. PMID 1270420  1
1976 Pandin M, Padlan EA, DiBello C, Chaiken IM. Crystalline semisynthetic ribonuclease-S'. Proceedings of the National Academy of Sciences of the United States of America. 73: 1844-7. PMID 1064856  1
1975 Dunn BM, Chaiken IM. Relationship between alpha-helical propensity and formation of the ribonuclease-S complex. Journal of Molecular Biology. 95: 497-511. PMID 1152063 DOI: 10.1016/0022-2836(75)90313-7  1
1975 Dunn BM, Chaiken IM. Evaluation of quantitative affinity chromatography by comparison with kinetic and equilibrium dialysis methods for the analysis of nucleotide binding to staphylococcal nuclease. Biochemistry. 14: 2343-9. PMID 1138865  1
1975 Chaiken IM, Randolph RE, Taylor HC. Conformational effects associated with the interaction of polypeptide ligands with neurophysins. Annals of the New York Academy of Sciences. 248: 442-50. PMID 1054558  1
1974 Chaiken IM, Cohen JS, Sokoloski EA. Microenvironment of histidine 12 in ribonuclease-S as detected by 13C nuclear magnetic resonance. Journal of the American Chemical Society. 96: 4703-5. PMID 4853212  1
1974 Chaiken IM. Carbon 13 as a probe of helix formation in semisynthetic ribonuclease-S'. The Journal of Biological Chemistry. 249: 1247-50. PMID 4814342  1
1974 Dunn BM, Chaiken IM. Quantitative affinity chromatography. Determination of binding constants by elution with competitive inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 71: 2382-5. PMID 4526212  1
1974 Chaiken IM. Functional purification of synthetic proteins and protein fragments. Methods in Enzymology. 34: 631-8. PMID 4476047 DOI: 10.1016/S0076-6879(74)34085-2  1
1974 Dunn BM, DiBello C, Kirk KL, Cohen LA, Chaiken IM. Synthesis, purification, and properties of a semisynthetic ribonuclease S incorporating 4-fluoro-L-histidine at position 12. The Journal of Biological Chemistry. 249: 6295-301. PMID 4420810  1
1973 Chaiken IM, Freedman MH, Lyerla JR, Cohen JS. Preparation and studies of 19 F-labeled and enriched 13 C-labeled semisynthetic ribonuclease-S' analogues. The Journal of Biological Chemistry. 248: 884-91. PMID 4684711  1
1973 Freedman MH, Lyerla JR, Chaiken IM, Cohen JS. Carbon-13 nuclear-magnetic-resonance studies on selected amino acids, peptides, and proteins. European Journal of Biochemistry / Febs. 32: 215-26. PMID 4631542  1
1973 Shifrin S, Solis BG, Chaiken IM. L Asparaginase from Erwinia carotovora. Physicochemical properties of the native and succinylated enzyme Journal of Biological Chemistry. 248: 3464-3469. PMID 4573979  1
1973 Sánchez GR, Chaiken IM, Anfinsen CB. Structure-function relationships at the active site of nuclease-T'. The Journal of Biological Chemistry. 248: 3653-9. PMID 4349872  1
1973 Dunn BM, DiBello C, Chaiken IM. Semisynthetic histidinyl 12 analogue complexes of ribonuclease S' Federation Proceedings. 32: 1818.  1
1972 Chaiken IM, Sánchez GR. Active site properties of (aspartic acid 43)-semisynthetic nuclease-T'. The Journal of Biological Chemistry. 247: 6743-7. PMID 4343156  1
1972 Chaiken IM. Chemical studies of structural features in staphylococcal nuclease-T'. The Journal of Biological Chemistry. 247: 1999-2007. PMID 4335858  1
1971 Chaiken IM, Anfinsen CB. Solic phase synthetic study of the active site region of staphylococcal nuclease-T'. The Journal of Biological Chemistry. 246: 2285-90. PMID 5576073  1
1971 Cohen JS, Feil M, Chaiken IM. Proton magnetic resonance studies of the tyrosine residues of staphylococcal nuclease using [3,5-2H2]tyrosine Bba - Protein Structure. 236: 468-478. PMID 5569481 DOI: 10.1016/0005-2795(71)90227-3  1
1971 Freedman MH, Cohen JS, Chaiken IM. Carbon-13 Fourier transform nuclear magnetic resonance studies of peptides Biochemical and Biophysical Research Communications. 42: 1148-1155. PMID 5550801 DOI: 10.1016/0006-291X(71)90025-8  1
1971 Chaiken IM. Purification and properties of semisynthetic staphylococcal nuclease-T' Journal of Biological Chemistry. 246: 2948-2952. PMID 4324344  1
1970 Mitchel RE, Chaiken IM, Smith EL. The complete amino acid sequence of papain. Additions and corrections. The Journal of Biological Chemistry. 245: 3485-92. PMID 5470818  1
1970 Chaiken IM, Anfinsen CB. A solid phase synthetic study of structure-function relationships in the amino-terminal region of staphylococcal nuclease. The Journal of Biological Chemistry. 245: 4718-23. PMID 5456145  1
1970 Chaiken IM, Anfinsen CB. A study of the role of histidine residue 46 in staphylococcal nuclease by solid phase peptide synthesis. The Journal of Biological Chemistry. 245: 2337-41. PMID 5442274  1
1969 Chaiken IM, Smith EL. Reaction of a specific tyrosine residue of papain with diisopropylfluorophosphate. The Journal of Biological Chemistry. 244: 4247-50. PMID 5800444  1
1969 Chaiken IM, Smith EL. Reaction of the sulfhydryl group of papain with chloroacetic acid. The Journal of Biological Chemistry. 244: 5095-9. PMID 5344123  1
1969 Chaiken IM, Smith EL. Reaction of chloroacetamide with the sulfhydryl group of papain. The Journal of Biological Chemistry. 244: 5087-94. PMID 5344122  1
Show low-probability matches.