Jason M. Crawford - Publications

Chemistry Yale University, New Haven, CT 
Chemical Biology

34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Healy AR, Vizcaino MI, Crawford JM, Herzon SB. A convergent and modular synthesis of candidate precolibactins. Structural revision of precolibactin A. Journal of the American Chemical Society. PMID 27025153 DOI: 10.1021/jacs.6b02276  1
2016 Vizcaino MI, Crawford JM. Secondary Metabolic Pathway-Targeted Metabolomics. Methods in Molecular Biology (Clifton, N.J.). 1401: 175-95. PMID 26831709 DOI: 10.1007/978-1-4939-3375-4_12  1
2015 Park HB, Crawford JM. Lumiquinone A, an α-Aminomalonate-Derived Aminobenzoquinone from Photorhabdus luminescens. Journal of Natural Products. 78: 1437-41. PMID 25988621 DOI: 10.1021/np500974f  1
2015 Vizcaino MI, Crawford JM. The colibactin warhead crosslinks DNA. Nature Chemistry. 7: 411-7. PMID 25901819 DOI: 10.1038/nchem.2221  1
2015 Engel P, Vizcaino MI, Crawford JM. Gut symbionts from distinct hosts exhibit genotoxic activity via divergent colibactin biosynthesis pathways. Applied and Environmental Microbiology. 81: 1502-12. PMID 25527542 DOI: 10.1128/AEM.03283-14  1
2014 Guo X, Crawford JM. An atypical orphan carbohydrate-NRPS genomic island encodes a novel lytic transglycosylase. Chemistry & Biology. 21: 1271-7. PMID 25219963 DOI: 10.1016/j.chembiol.2014.07.025  1
2014 Vizcaino MI, Engel P, Trautman E, Crawford JM. Comparative metabolomics and structural characterizations illuminate colibactin pathway-dependent small molecules. Journal of the American Chemical Society. 136: 9244-7. PMID 24932672 DOI: 10.1021/ja503450q  1
2014 Vizcaino MI, Guo X, Crawford JM. Merging chemical ecology with bacterial genome mining for secondary metabolite discovery. Journal of Industrial Microbiology & Biotechnology. 41: 285-99. PMID 24127069 DOI: 10.1007/s10295-013-1356-5  1
2013 Vagstad AL, Newman AG, Storm PA, Belecki K, Crawford JM, Townsend CA. Combinatorial domain swaps provide insights into the rules of fungal polyketide synthase programming and the rational synthesis of non-native aromatic products. Angewandte Chemie (International Ed. in English). 52: 1718-21. PMID 23283670 DOI: 10.1002/anie.201208550  1
2012 Somvanshi VS, Sloup RE, Crawford JM, Martin AR, Heidt AJ, Kim KS, Clardy J, Ciche TA. A single promoter inversion switches Photorhabdus between pathogenic and mutualistic states. Science (New York, N.Y.). 337: 88-93. PMID 22767929 DOI: 10.1126/science.1216641  1
2012 Crawford JM, Portmann C, Zhang X, Roeffaers MB, Clardy J. Small molecule perimeter defense in entomopathogenic bacteria. Proceedings of the National Academy of Sciences of the United States of America. 109: 10821-6. PMID 22711807 DOI: 10.1073/pnas.1201160109  1
2012 Crawford JM, Clardy J. Microbial genome mining answers longstanding biosynthetic questions. Proceedings of the National Academy of Sciences of the United States of America. 109: 7589-90. PMID 22550177 DOI: 10.1073/pnas.1205361109  1
2011 Crawford JM, Mahlstedt SA, Malcolmson SJ, Clardy J, Walsh CT. Dihydrophenylalanine: a prephenate-derived Photorhabdus luminescens antibiotic and intermediate in dihydrostilbene biosynthesis. Chemistry & Biology. 18: 1102-12. PMID 21944749 DOI: 10.1016/j.chembiol.2011.07.009  1
2011 Crawford JM, Portmann C, Kontnik R, Walsh CT, Clardy J. NRPS substrate promiscuity diversifies the xenematides. Organic Letters. 13: 5144-7. PMID 21888371 DOI: 10.1021/ol2020237  1
2011 Crawford JM, Clardy J. Bacterial symbionts and natural products. Chemical Communications (Cambridge, England). 47: 7559-66. PMID 21594283 DOI: 10.1039/c1cc11574j  1
2010 Crawford JM, Townsend CA. New insights into the formation of fungal aromatic polyketides. Nature Reviews. Microbiology. 8: 879-89. PMID 21079635 DOI: 10.1038/nrmicro2465  1
2010 Crawford JM, Clardy J. Biosynthesis: not just passing through. Nature Chemistry. 2: 805-7. PMID 20861892 DOI: 10.1038/nchem.848  1
2010 Kontnik R, Crawford JM, Clardy J. Exploiting a global regulator for small molecule discovery in Photorhabdus luminescens. Acs Chemical Biology. 5: 659-65. PMID 20524642 DOI: 10.1021/cb100117k  1
2010 D'Onofrio A, Crawford JM, Stewart EJ, Witt K, Gavrish E, Epstein S, Clardy J, Lewis K. Siderophores from neighboring organisms promote the growth of uncultured bacteria. Chemistry & Biology. 17: 254-64. PMID 20338517 DOI: 10.1016/j.chembiol.2010.02.010  1
2010 Korman TP, Crawford JM, Labonte JW, Newman AG, Wong J, Townsend CA, Tsai SC. Structure and function of an iterative polyketide synthase thioesterase domain catalyzing Claisen cyclization in aflatoxin biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 6246-51. PMID 20332208 DOI: 10.1073/pnas.0913531107  1
2010 Ehrlich KC, Chang PK, Scharfenstein LL, Cary JW, Crawford JM, Townsend CA. Absence of the aflatoxin biosynthesis gene, norA, allows accumulation of deoxyaflatoxin B1 in Aspergillus flavus cultures. Fems Microbiology Letters. 305: 65-70. PMID 20158523 DOI: 10.1111/j.1574-6968.2010.01914.x  1
2010 Crawford JM, Kontnik R, Clardy J. Regulating alternative lifestyles in entomopathogenic bacteria. Current Biology : Cb. 20: 69-74. PMID 20022247 DOI: 10.1016/j.cub.2009.10.059  1
2010 Seo JK, Stephenson J, Crawford JM, Stone KL, Noga EJ. American oyster, Crassostrea virginica, expresses a potent antibacterial histone H2B protein. Marine Biotechnology (New York, N.Y.). 12: 543-51. PMID 19949827 DOI: 10.1007/s10126-009-9240-z  1
2009 Crawford JM, Korman TP, Labonte JW, Vagstad AL, Hill EA, Kamari-Bidkorpeh O, Tsai SC, Townsend CA. Structural basis for biosynthetic programming of fungal aromatic polyketide cyclization. Nature. 461: 1139-43. PMID 19847268 DOI: 10.1038/nature08475  1
2009 Belecki K, Crawford JM, Townsend CA. Production of octaketide polyenes by the calicheamicin polyketide synthase CalE8: implications for the biosynthesis of enediyne core structures. Journal of the American Chemical Society. 131: 12564-6. PMID 19689130 DOI: 10.1021/ja904391r  1
2008 Crawford JM, Vagstad AL, Ehrlich KC, Udwary DW, Townsend CA. Acyl-carrier protein-phosphopantetheinyltransferase partnerships in fungal fatty acid synthases. Chembiochem : a European Journal of Chemical Biology. 9: 1559-63. PMID 18551496 DOI: 10.1002/cbic.200700659  1
2008 Crawford JM, Thomas PM, Scheerer JR, Vagstad AL, Kelleher NL, Townsend CA. Deconstruction of iterative multidomain polyketide synthase function. Science (New York, N.Y.). 320: 243-6. PMID 18403714 DOI: 10.1126/science.1154711  1
2008 Crawford JM, Vagstad AL, Whitworth KP, Ehrlich KC, Townsend CA. Synthetic strategy of nonreducing iterative polyketide synthases and the origin of the classical "starter-unit effect". Chembiochem : a European Journal of Chemical Biology. 9: 1019-23. PMID 18338425 DOI: 10.1002/cbic.200700702  1
2008 Crawford JM, Vagstad AL, Ehrlich KC, Townsend CA. Starter unit specificity directs genome mining of polyketide synthase pathways in fungi. Bioorganic Chemistry. 36: 16-22. PMID 18215412 DOI: 10.1016/j.bioorg.2007.11.002  1
2007 Stone KL, Bjornson RD, Blasko GG, Bruce C, Cofrancesco R, Carriero NJ, Colangelo CM, Crawford JK, Crawford JM, daSilva NC, Deluca JD, Elliott JI, Elliott MM, Flory PJ, Folta-Stogniew EJ, et al. Keck Foundation Biotechnology Resource Laboratory, Yale University. The Yale Journal of Biology and Medicine. 80: 195-211. PMID 18449392  1
2006 Crawford JM, Dancy BC, Hill EA, Udwary DW, Townsend CA. Identification of a starter unit acyl-carrier protein transacylase domain in an iterative type I polyketide synthase. Proceedings of the National Academy of Sciences of the United States of America. 103: 16728-33. PMID 17071746 DOI: 10.1073/pnas.0604112103  1
2006 Townsend CA, Crawford JM, Bililign T. New images evoke FAScinating questions. Chemistry & Biology. 13: 349-51. PMID 16632247 DOI: 10.1016/j.chembiol.2006.04.001  1
2005 Seo JK, Crawford JM, Stone KL, Noga EJ. Purification of a novel arthropod defensin from the American oyster, Crassostrea virginica. Biochemical and Biophysical Research Communications. 338: 1998-2004. PMID 16297885 DOI: 10.1016/j.bbrc.2005.11.013  1
2005 Brune D, Crawford JM, Cook RG, Denslow ND, Kobayashi R, Madden BJ, Neveu JM, Steinke L. Edman sequencing research group 2004 study: Modified amino acids in Edman sequencing Journal of Biomolecular Techniques. 16: 272-284.  1
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