| Year |
Citation |
Score |
| 2024 |
Hamchand R, Wang K, Song D, Palm NW, Crawford JM. Mucosal sugars delineate pyrazine vs pyrazinone autoinducer signaling in Klebsiella oxytoca. Nature Communications. 15: 8902. PMID 39406708 DOI: 10.1038/s41467-024-53185-6 |
0.812 |
|
| 2024 |
Turocy T, Crawford JM. Bacterial small molecule metabolites implicated in gastrointestinal cancer development. Nature Reviews. Microbiology. PMID 39375475 DOI: 10.1038/s41579-024-01103-4 |
0.786 |
|
| 2024 |
Dudkina N, Park HB, Song D, Jain A, Khan SA, Flavell RA, Johnson CH, Palm NW, Crawford JM. Human AKR1C3 binds agonists of GPR84 and participates in an expanded polyamine pathway. Cell Chemical Biology. PMID 39163853 DOI: 10.1016/j.chembiol.2024.07.011 |
0.815 |
|
| 2024 |
Martins FH, Rosay T, Rajan A, Carter HE, Turocy T, Mejia A, Crawford JM, Maresso AW, Sperandio V. Enterococcus faecalis-derived adenine enhances enterohaemorrhagic Escherichia coli Type 3 Secretion System-dependent virulence. Nature Microbiology. PMID 38965331 DOI: 10.1038/s41564-024-01747-1 |
0.804 |
|
| 2024 |
Lam YC, Hamchand R, Mucci NC, Kauffman SJ, Dudkina N, Reagle EV, Casanova-Torres ÁM, DeCuyper J, Chen H, Song D, Thomas MG, Palm NW, Goodrich-Blair H, Crawford JM. The LrhA transcriptional regulator modulates production of γ-keto--acyl amides with inhibitory activity against mutualistic host nematode egg hatching. Applied and Environmental Microbiology. e0052824. PMID 38916293 DOI: 10.1128/aem.00528-24 |
0.814 |
|
| 2024 |
Huseman ED, Lo A, Fedorova O, Elia JL, Gueble SE, Lin K, Sundaram RK, Oh J, Liu J, Menges F, Rees MG, Ronan MM, Roth JA, Batista VS, Crawford JM, et al. Mechanism of Action of KL-50, a Candidate Imidazotetrazine for the Treatment of Drug-Resistant Brain Cancers. Journal of the American Chemical Society. PMID 38815248 DOI: 10.1021/jacs.3c06483 |
0.591 |
|
| 2024 |
York AG, Skadow MH, Oh J, Qu R, Zhou QD, Hsieh WY, Mowel WK, Brewer JR, Kaffe E, Williams KJ, Kluger Y, Smale ST, Crawford JM, Bensinger SJ, Flavell RA. IL-10 constrains sphingolipid metabolism to limit inflammation. Nature. PMID 38383790 DOI: 10.1038/s41586-024-07098-5 |
0.629 |
|
| 2023 |
Ontai-Brenning A, Hamchand R, Crawford JM, Goodman AL. Gut microbes modulate (p)ppGpp during a time-restricted feeding regimen. Mbio. e0190723. PMID 37971266 DOI: 10.1128/mbio.01907-23 |
0.801 |
|
| 2023 |
Wei Z, Oh J, Flavell RA, Crawford JM. Author Correction: LACC1 bridges NOS2 and polyamine metabolism in inflammatory macrophages. Nature. PMID 37231312 DOI: 10.1038/s41586-023-06244-9 |
0.664 |
|
| 2023 |
York AG, Skadow MH, Qu R, Oh J, Mowel WK, Brewer JR, Kaffe E, Williams KJ, Kluger Y, Crawford JM, Smale ST, Bensinger SJ, Flavell RA. IL-10 constrains sphingolipid metabolism via fatty acid desaturation to limit inflammation. Biorxiv : the Preprint Server For Biology. PMID 37214856 DOI: 10.1101/2023.05.07.539780 |
0.625 |
|
| 2023 |
Urdaneta-Páez V, Hamchand R, Anthony K, Crawford J, Sutherland AG, Kazmierczak BI. Identification of Efflux Substrates Using a Riboswitch-Based Reporter in Pseudomonas aeruginosa. Msphere. e0006923. PMID 36946743 DOI: 10.1128/msphere.00069-23 |
0.796 |
|
| 2023 |
Urdaneta-Páez V, Hamchand R, Anthony K, Crawford J, Sutherland AG, Kazmierczak BI. Identification of efflux substrates using a riboswitch-based reporter in . Biorxiv : the Preprint Server For Biology. PMID 36909469 DOI: 10.1101/2023.02.27.530370 |
0.794 |
|
| 2022 |
Gatsios A, Kim CS, York AG, Flavell RA, Crawford JM. Cellular Stress-Induced Metabolites in . Journal of Natural Products. PMID 36346625 DOI: 10.1021/acs.jnatprod.2c00706 |
0.813 |
|
| 2022 |
Cao Y, Oh J, Xue M, Huh WJ, Wang J, Gonzalez-Hernandez JA, Rice TA, Martin AL, Song D, Crawford JM, Herzon SB, Palm NW. Commensal microbiota from patients with inflammatory bowel disease produce genotoxic metabolites. Science (New York, N.Y.). 378: eabm3233. PMID 36302024 DOI: 10.1126/science.abm3233 |
0.661 |
|
| 2022 |
Cho W, York AG, Wang R, Wyche TP, Piizzi G, Flavell R, Crawford J. N -acyl amides from Neisseria meningitidis and their role in sphingosine receptor signaling. Chembiochem : a European Journal of Chemical Biology. PMID 36112057 DOI: 10.1002/cbic.202200490 |
0.799 |
|
| 2022 |
Wei Z, Oh J, Flavell RA, Crawford JM. LACC1 bridges NOS2 and polyamine metabolism in inflammatory macrophages. Nature. PMID 35978195 DOI: 10.1038/s41586-022-05111-3 |
0.701 |
|
| 2022 |
Ding C, Xu H, Yu Z, Roulis M, Qu R, Zhou J, Oh J, Crawford J, Gao Y, Jackson R, Sefik E, Li S, Wei Z, Skadow M, Yin Z, et al. RNA mA demethylase ALKBH5 regulates the development of γδ T cells. Proceedings of the National Academy of Sciences of the United States of America. 119: e2203318119. PMID 35939687 DOI: 10.1073/pnas.2203318119 |
0.657 |
|
| 2022 |
Patel JR, Oh J, Wang S, Crawford JM, Isaacs FJ. Cross-kingdom expression of synthetic genetic elements promotes discovery of metabolites in the human microbiome. Cell. PMID 35366417 DOI: 10.1016/j.cell.2022.03.008 |
0.78 |
|
| 2021 |
Li JH, Cho W, Hamchand R, Oh J, Crawford JM. A Conserved Nonribosomal Peptide Synthetase in Produces Citrulline-Functionalized Lipopeptides. Journal of Natural Products. PMID 34581573 DOI: 10.1021/acs.jnatprod.1c00573 |
0.79 |
|
| 2021 |
Gatsios A, Kim CS, Crawford JM. Escherichia coli small molecule metabolism at the host-microorganism interface. Nature Chemical Biology. PMID 34552219 DOI: 10.1038/s41589-021-00807-5 |
0.812 |
|
| 2021 |
Kim CS, Turocy T, Moon G, Shine EE, Crawford JM. -Derived γ-Lactams and Structurally Related Metabolites Are Produced at the Intersection of Colibactin and Fatty Acid Biosynthesis. Organic Letters. PMID 34406772 DOI: 10.1021/acs.orglett.1c02461 |
0.795 |
|
| 2021 |
Shine EE, Crawford JM. Molecules from the Microbiome. Annual Review of Biochemistry. PMID 33770448 DOI: 10.1146/annurev-biochem-080320-115307 |
0.812 |
|
| 2021 |
Schorn MA, Verhoeven S, Ridder L, Huber F, Acharya DD, Aksenov AA, Aleti G, Moghaddam JA, Aron AT, Aziz S, Bauermeister A, Bauman KD, Baunach M, Beemelmanns C, Beman JM, ... ... Crawford JM, et al. A community resource for paired genomic and metabolomic data mining. Nature Chemical Biology. PMID 33589842 DOI: 10.1038/s41589-020-00724-z |
0.755 |
|
| 2020 |
Turocy T, Crawford JM. Dual Targeting of v-ATPase and mTORC1 Signaling Disarms Multidrug-Resistant Cancers. Cell Chemical Biology. 27: 1329-1331. PMID 33217311 DOI: 10.1016/j.chembiol.2020.10.013 |
0.769 |
|
| 2020 |
Wiemann J, Crawford JM, Briggs DEG. Phylogenetic and physiological signals in metazoan fossil biomolecules. Science Advances. 6: eaba6883. PMID 32832604 DOI: 10.1126/Sciadv.Aba6883 |
0.351 |
|
| 2020 |
Park HB, Wei Z, Oh J, Xu H, Kim CS, Wang R, Wyche TP, Piizzi G, Flavell RA, Crawford JM. Sulfamethoxazole drug stress upregulates antioxidant immunomodulatory metabolites in Escherichia coli. Nature Microbiology. PMID 32719505 DOI: 10.1038/S41564-020-0763-4 |
0.818 |
|
| 2020 |
Li JH, Oh J, Kienesberger S, Kim NY, Clarke DJ, Zechner EL, Crawford J. Making and breaking leupeptin protease inhibitors in pathogenic gammaproteobacteria. Angewandte Chemie (International Ed. in English). PMID 32609431 DOI: 10.1002/Anie.202005506 |
0.811 |
|
| 2020 |
Wernke KM, Xue M, Tirla A, Kim CS, Crawford JM, Herzon SB. Structure and bioactivity of colibactin. Bioorganic & Medicinal Chemistry Letters. 30: 127280. PMID 32527463 DOI: 10.1016/J.Bmcl.2020.127280 |
0.667 |
|
| 2020 |
Goddard T, Patel JR, Park HB, Crawford JM. Dimeric Stilbene Antibiotics Target the Bacterial Cell Wall in Drug-resistant Gram-positive Pathogens. Biochemistry. PMID 32410442 DOI: 10.1021/Acs.Biochem.0C00213 |
0.789 |
|
| 2020 |
Adaku N, Park HB, Spakowicz DJ, Tiwari MK, Strobel SA, Crawford JM, Rogers FA. A DNA Repair Inhibitor Isolated from an Ecuadorian Fungal Endophyte Exhibits Synthetic Lethality in PTEN-Deficient Glioblastoma. Journal of Natural Products. PMID 32407116 DOI: 10.1021/Acs.Jnatprod.0C00012 |
0.684 |
|
| 2020 |
Kim CS, Li JH, Barco B, Park HB, Gatsios A, Damania A, Wang R, Wyche TP, Piizzi G, Clay NK, Crawford JM. Cellular Stress Upregulates Indole Signaling Metabolites in Escherichia coli. Cell Chemical Biology. PMID 32243812 DOI: 10.1016/J.Chembiol.2020.03.003 |
0.787 |
|
| 2020 |
Kim CS, Gatsios A, Cuesta S, Lam YC, Wei Z, Chen H, Russell RM, Shine EE, Wang R, Wyche TP, Piizzi G, Flavell RA, Palm NW, Sperandio V, Crawford JM. Characterization of Autoinducer-3 Structure and Biosynthesis in . Acs Central Science. 6: 197-206. PMID 32123737 DOI: 10.1021/Acscentsci.9B01076 |
0.805 |
|
| 2020 |
Park HB, Goddard TN, Oh J, Patel J, Wei Z, Perez CE, Mercado BQ, Wang R, Wyche TP, Piizzi G, Flavell RA, Crawford J. Bacterial Autoimmune Drug Metabolism Transforms an Immunomodulator into Structurally and Functionally Divergent Antibiotics. Angewandte Chemie (International Ed. in English). PMID 32097515 DOI: 10.1002/Anie.201916204 |
0.795 |
|
| 2019 |
Healy AR, Wernke KM, Kim CS, Lees NR, Crawford JM, Herzon SB. Addendum: Synthesis and reactivity of precolibactin 886. Nature Chemistry. PMID 31719668 DOI: 10.1038/S41557-019-0383-X |
0.559 |
|
| 2019 |
Yang J, Schleicher TR, Dong Y, Park HB, Lan J, Cresswell P, Crawford J, Dimopoulos G, Fikrig E. Disruption of in impairs ovarian development and infection. The Journal of Experimental Medicine. PMID 31658986 DOI: 10.1084/Jem.20190682 |
0.675 |
|
| 2019 |
Healy AR, Wernke KM, Kim CS, Lees NR, Crawford JM, Herzon SB. Synthesis and reactivity of precolibactin 886. Nature Chemistry. 11: 890-898. PMID 31548676 DOI: 10.1038/S41557-019-0338-2 |
0.674 |
|
| 2019 |
Oh J, Kim NY, Chen H, Palm NW, Crawford JM. An Ugi-like Biosynthetic Pathway Encodes Bombesin Receptor Sub-type-3 Agonists. Journal of the American Chemical Society. PMID 31537063 DOI: 10.1021/Jacs.9B04183 |
0.678 |
|
| 2019 |
Park HB, Lam YC, Gaffney JP, Weaver JC, Krivoshik SR, Hamchand R, Pieribone V, Gruber DF, Crawford JM. Bright Green Biofluorescence in Sharks Derives from Bromo-Kynurenine Metabolism. Iscience. PMID 31402257 DOI: 10.1016/J.Isci.2019.07.019 |
0.786 |
|
| 2019 |
Xue M, Kim CS, Healy AR, Wernke KM, Wang Z, Frischling MC, Shine EE, Wang W, Herzon SB, Crawford JM. Structure elucidation of colibactin and its DNA cross-links. Science (New York, N.Y.). PMID 31395743 DOI: 10.1126/Science.Aax2685 |
0.81 |
|
| 2019 |
Kim NY, Goddard TN, Sohn S, Spiegel DA, Crawford J. Biocatalytic Reversal of Advanced Glycation End Product Modification. Chembiochem : a European Journal of Chemical Biology. PMID 31013547 DOI: 10.1002/Cbic.201900158 |
0.642 |
|
| 2019 |
Chen H, Nwe PK, Yang Y, Rosen CE, Bielecka AA, Kuchroo M, Cline GW, Kruse AC, Ring AM, Crawford JM, Palm NW. A Forward Chemical Genetic Screen Reveals Gut Microbiota Metabolites That Modulate Host Physiology. Cell. PMID 31006530 DOI: 10.1016/J.Cell.2019.03.036 |
0.792 |
|
| 2019 |
Wei Z, Crawford JM. The Gut Microbiome Says NO to microRNA-Mediated Gene Silencing. Biochemistry. PMID 30951635 DOI: 10.1021/Acs.Biochem.9B00262 |
0.482 |
|
| 2019 |
Lozano GL, Park HB, Bravo JI, Armstrong EA, Denu JM, Stabb EV, Broderick NA, Crawford JM, Handelsman J. Bacterial analogs of plant tetrahydropyridine alkaloids mediate microbial interactions in a rhizosphere model system. Applied and Environmental Microbiology. PMID 30877115 DOI: 10.1128/Aem.03058-18 |
0.725 |
|
| 2019 |
Lozano GL, Bravo JI, Garavito Diago MF, Park HB, Hurley A, Peterson SB, Stabb EV, Crawford JM, Broderick NA, Handelsman J. Introducing THOR, a Model Microbiome for Genetic Dissection of Community Behavior. Mbio. 10. PMID 30837345 DOI: 10.1128/Mbio.02846-18 |
0.675 |
|
| 2019 |
Perez CE, Crawford JM. Characterization of a Hybrid Nonribosomal Peptide-Carbohydrate Biosynthetic Pathway in Photorhabdus luminescens. Biochemistry. PMID 30694662 DOI: 10.1021/Acs.Biochem.8B01120 |
0.348 |
|
| 2018 |
Shine EE, Xue M, Patel JR, Healy AR, Surovtseva YV, Herzon SB, Crawford JM. Model colibactins exhibit human cell genotoxicity in the absence of host bacteria. Acs Chemical Biology. PMID 30403848 DOI: 10.1021/Acschembio.8B00714 |
0.805 |
|
| 2018 |
Xue M, Shine EE, Wang W, Crawford JM, Herzon SB. Characterization of natural colibactin-nucleobase adducts by tandem MS and isotopic labeling. Support for DNA alkylation by cyclopropane ring opening. Biochemistry. PMID 30365310 DOI: 10.1021/Acs.Biochem.8B01023 |
0.793 |
|
| 2018 |
Tessler M, Gaffney JP, Crawford JM, Trautman E, Gujarati NA, Alatalo P, Pieribone VA, Gruber DF. Luciferin production and luciferase transcription in the bioluminescent copepod . Peerj. 6: e5506. PMID 30233994 DOI: 10.7717/Peerj.5506 |
0.322 |
|
| 2018 |
Oh J, Patel J, Park HB, Crawford JM. β-lactam Biotransformations Activate Innate Immunity. The Journal of Organic Chemistry. PMID 29616809 DOI: 10.1021/Acs.Joc.8B00241 |
0.809 |
|
| 2018 |
Lam YC, Crawford JM. Discovering antibiotics from the global microbiome. Nature Microbiology. 3: 392-393. PMID 29588534 DOI: 10.1038/S41564-018-0135-5 |
0.678 |
|
| 2018 |
Patel J, Crawford JM. Microbiota-Regulated Outcomes of Human Cancer Immunotherapy via the PD-1/PD-L1 Axis. Biochemistry. PMID 29350031 DOI: 10.1021/Acs.Biochem.7B01249 |
0.588 |
|
| 2018 |
STREETER M, GODDARD TN, CRAWFORD JM, SPIEGEL DA. Identification of Glucosepane Cross-Link Breaking Enzymes Diabetes. 67: 1229-P. DOI: 10.2337/Db18-1229-P |
0.662 |
|
| 2017 |
Tripathi P, Shine EE, Healy AR, Kim CS, Herzon SB, Bruner SD, Crawford JM. ClbS is a cyclopropane hydrolase that confers colibactin resistance. Journal of the American Chemical Society. PMID 29112397 DOI: 10.1021/Jacs.7B09971 |
0.815 |
|
| 2017 |
Perez CE, Park HB, Crawford JM. Functional Characterization of a Condensation Domain that Links Nonribosomal Peptide and Pteridine Biosynthetic Machineries in Photorhabdus luminescens. Biochemistry. PMID 29111689 DOI: 10.1021/Acs.Biochem.7B00863 |
0.754 |
|
| 2017 |
Guntaka NS, Healy AR, Crawford JM, Herzon SB, Bruner SD. Structure and Functional Analysis of ClbQ, an Unusual Intermediate-Releasing Thioesterase from the Colibactin Biosynthetic Pathway. Acs Chemical Biology. PMID 28846367 DOI: 10.1021/Acschembio.7B00479 |
0.463 |
|
| 2017 |
Park HB, Perez CE, Barber KW, Rinehart J, Crawford JM. Genome mining unearths a hybrid nonribosomal peptide synthetase-like-pteridine synthase biosynthetic gene cluster. Elife. 6. PMID 28431213 DOI: 10.7554/Elife.25229 |
0.73 |
|
| 2017 |
Park HB, Sampathkumar P, Perez CE, Lee JH, Tran J, Bonanno JB, Hallem EA, Almo SC, Crawford JM. Stilbene epoxidation and detoxification in a Photorhabdus luminescens-nematode symbiosis. The Journal of Biological Chemistry. PMID 28246174 DOI: 10.1074/Jbc.M116.762542 |
0.737 |
|
| 2017 |
Trautman E, Healy AR, Shine E, Herzon SB, Crawford JM. Domain-targeted metabolomics delineates the heterocycle assembly steps of colibactin biosynthesis. Journal of the American Chemical Society. PMID 28240912 DOI: 10.1021/Jacs.7B00659 |
0.815 |
|
| 2017 |
Tørring T, Shames SR, Cho W, Roy CR, Crawford J. Acyl-histidines: New N-acyl amides from Legionella pneumophila. Chembiochem : a European Journal of Chemical Biology. PMID 28116768 DOI: 10.1002/Cbic.201600618 |
0.818 |
|
| 2017 |
Fischer C, Trautman EP, Crawford JM, Stabb EV, Handelsman J, Broderick NA. Metabolite exchange between microbiome members produces compounds that influence Drosophila behavior. Elife. 6. PMID 28068220 DOI: 10.7554/Elife.18855 |
0.364 |
|
| 2017 |
Park HB, Perez CE, Barber KW, Rinehart J, Crawford JM. Author response: Genome mining unearths a hybrid nonribosomal peptide synthetase-like-pteridine synthase biosynthetic gene cluster Elife. DOI: 10.7554/Elife.25229.037 |
0.659 |
|
| 2016 |
Trautman EP, Crawford JM. Linking Biosynthetic Gene Clusters to their Metabolites via Pathway-Targeted Molecular Networking. Current Topics in Medicinal Chemistry. 16: 1705-1716. PMID 28442948 |
0.328 |
|
| 2016 |
Healy AR, Nikolayevskiy H, Patel JR, Crawford JM, Herzon SB. A Mechanistic Model for Colibactin-Induced Genotoxicity. Journal of the American Chemical Society. 138: 15563-15570. PMID 27934011 DOI: 10.1021/Jacs.6B10354 |
0.667 |
|
| 2016 |
Park HB, Crawford JM. Pyrazinone protease inhibitor metabolites from Photorhabdus luminescens. The Journal of Antibiotics. PMID 27353165 DOI: 10.1038/Ja.2016.79 |
0.715 |
|
| 2016 |
Park HB, Perez CE, Perry EK, Crawford JM. Activating and Attenuating the Amicoumacin Antibiotics. Molecules (Basel, Switzerland). 21. PMID 27347911 DOI: 10.3390/Molecules21070824 |
0.73 |
|
| 2016 |
Healy AR, Vizcaino MI, Crawford JM, Herzon SB. A convergent and modular synthesis of candidate precolibactins. Structural revision of precolibactin A. Journal of the American Chemical Society. PMID 27025153 DOI: 10.1021/Jacs.6B02276 |
0.391 |
|
| 2016 |
Vizcaino MI, Crawford JM. Secondary Metabolic Pathway-Targeted Metabolomics. Methods in Molecular Biology (Clifton, N.J.). 1401: 175-95. PMID 26831709 DOI: 10.1007/978-1-4939-3375-4_12 |
0.335 |
|
| 2015 |
Trautman EP, Crawford JM. Linking Biosynthetic Gene Clusters to their Metabolites via Pathway-Targeted Molecular Networking. Current Topics in Medicinal Chemistry. PMID 26456470 DOI: 10.2174/1568026616666151012111046 |
0.439 |
|
| 2015 |
Park HB, Crawford JM. Lumiquinone A, an α-Aminomalonate-Derived Aminobenzoquinone from Photorhabdus luminescens. Journal of Natural Products. 78: 1437-41. PMID 25988621 DOI: 10.1021/Np500974F |
0.7 |
|
| 2015 |
Vizcaino MI, Crawford JM. The colibactin warhead crosslinks DNA. Nature Chemistry. 7: 411-7. PMID 25901819 DOI: 10.1038/Nchem.2221 |
0.432 |
|
| 2015 |
Engel P, Vizcaino MI, Crawford JM. Gut symbionts from distinct hosts exhibit genotoxic activity via divergent colibactin biosynthesis pathways. Applied and Environmental Microbiology. 81: 1502-12. PMID 25527542 DOI: 10.1128/Aem.03283-14 |
0.453 |
|
| 2015 |
Vizcaino M, Trautman E, Engel P, Shine E, Crawford J. Discovering and deciphering the pathogenic and probiotic activities from the bacterial colibactin pathway Planta Medica. 81. DOI: 10.1055/s-0035-1556137 |
0.81 |
|
| 2014 |
Guo X, Crawford JM. An atypical orphan carbohydrate-NRPS genomic island encodes a novel lytic transglycosylase. Chemistry & Biology. 21: 1271-7. PMID 25219963 DOI: 10.1016/J.Chembiol.2014.07.025 |
0.38 |
|
| 2014 |
Vizcaino MI, Engel P, Trautman E, Crawford JM. Comparative metabolomics and structural characterizations illuminate colibactin pathway-dependent small molecules. Journal of the American Chemical Society. 136: 9244-7. PMID 24932672 DOI: 10.1021/Ja503450Q |
0.429 |
|
| 2014 |
Vizcaino MI, Guo X, Crawford JM. Merging chemical ecology with bacterial genome mining for secondary metabolite discovery. Journal of Industrial Microbiology & Biotechnology. 41: 285-99. PMID 24127069 DOI: 10.1007/S10295-013-1356-5 |
0.495 |
|
| 2013 |
Vagstad AL, Newman AG, Storm PA, Belecki K, Crawford JM, Townsend CA. Combinatorial domain swaps provide insights into the rules of fungal polyketide synthase programming and the rational synthesis of non-native aromatic products. Angewandte Chemie (International Ed. in English). 52: 1718-21. PMID 23283670 DOI: 10.1002/Anie.201208550 |
0.781 |
|
| 2012 |
Somvanshi VS, Sloup RE, Crawford JM, Martin AR, Heidt AJ, Kim KS, Clardy J, Ciche TA. A single promoter inversion switches Photorhabdus between pathogenic and mutualistic states. Science (New York, N.Y.). 337: 88-93. PMID 22767929 DOI: 10.1126/Science.1216641 |
0.484 |
|
| 2012 |
Crawford JM, Portmann C, Zhang X, Roeffaers MB, Clardy J. Small molecule perimeter defense in entomopathogenic bacteria. Proceedings of the National Academy of Sciences of the United States of America. 109: 10821-6. PMID 22711807 DOI: 10.1073/Pnas.1201160109 |
0.522 |
|
| 2012 |
Crawford JM, Clardy J. Microbial genome mining answers longstanding biosynthetic questions. Proceedings of the National Academy of Sciences of the United States of America. 109: 7589-90. PMID 22550177 DOI: 10.1073/Pnas.1205361109 |
0.522 |
|
| 2011 |
Crawford JM, Mahlstedt SA, Malcolmson SJ, Clardy J, Walsh CT. Dihydrophenylalanine: a prephenate-derived Photorhabdus luminescens antibiotic and intermediate in dihydrostilbene biosynthesis. Chemistry & Biology. 18: 1102-12. PMID 21944749 DOI: 10.1016/J.Chembiol.2011.07.009 |
0.492 |
|
| 2011 |
Crawford JM, Portmann C, Kontnik R, Walsh CT, Clardy J. NRPS substrate promiscuity diversifies the xenematides. Organic Letters. 13: 5144-7. PMID 21888371 DOI: 10.1021/Ol2020237 |
0.792 |
|
| 2011 |
Crawford JM, Clardy J. Bacterial symbionts and natural products. Chemical Communications (Cambridge, England). 47: 7559-66. PMID 21594283 DOI: 10.1039/C1Cc11574J |
0.523 |
|
| 2010 |
Crawford JM, Townsend CA. New insights into the formation of fungal aromatic polyketides. Nature Reviews. Microbiology. 8: 879-89. PMID 21079635 DOI: 10.1038/Nrmicro2465 |
0.574 |
|
| 2010 |
Crawford JM, Clardy J. Biosynthesis: not just passing through. Nature Chemistry. 2: 805-7. PMID 20861892 DOI: 10.1038/Nchem.848 |
0.489 |
|
| 2010 |
Kontnik R, Crawford JM, Clardy J. Exploiting a global regulator for small molecule discovery in Photorhabdus luminescens. Acs Chemical Biology. 5: 659-65. PMID 20524642 DOI: 10.1021/Cb100117K |
0.805 |
|
| 2010 |
D'Onofrio A, Crawford JM, Stewart EJ, Witt K, Gavrish E, Epstein S, Clardy J, Lewis K. Siderophores from neighboring organisms promote the growth of uncultured bacteria. Chemistry & Biology. 17: 254-64. PMID 20338517 DOI: 10.1016/J.Chembiol.2010.02.010 |
0.454 |
|
| 2010 |
Korman TP, Crawford JM, Labonte JW, Newman AG, Wong J, Townsend CA, Tsai SC. Structure and function of an iterative polyketide synthase thioesterase domain catalyzing Claisen cyclization in aflatoxin biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 6246-51. PMID 20332208 DOI: 10.1073/Pnas.0913531107 |
0.762 |
|
| 2010 |
Ehrlich KC, Chang PK, Scharfenstein LL, Cary JW, Crawford JM, Townsend CA. Absence of the aflatoxin biosynthesis gene, norA, allows accumulation of deoxyaflatoxin B1 in Aspergillus flavus cultures. Fems Microbiology Letters. 305: 65-70. PMID 20158523 DOI: 10.1111/J.1574-6968.2010.01914.X |
0.563 |
|
| 2010 |
Crawford JM, Kontnik R, Clardy J. Regulating alternative lifestyles in entomopathogenic bacteria. Current Biology : Cb. 20: 69-74. PMID 20022247 DOI: 10.1016/J.Cub.2009.10.059 |
0.822 |
|
| 2009 |
Crawford JM, Korman TP, Labonte JW, Vagstad AL, Hill EA, Kamari-Bidkorpeh O, Tsai SC, Townsend CA. Structural basis for biosynthetic programming of fungal aromatic polyketide cyclization. Nature. 461: 1139-43. PMID 19847268 DOI: 10.1038/Nature08475 |
0.789 |
|
| 2009 |
Belecki K, Crawford JM, Townsend CA. Production of octaketide polyenes by the calicheamicin polyketide synthase CalE8: implications for the biosynthesis of enediyne core structures. Journal of the American Chemical Society. 131: 12564-6. PMID 19689130 DOI: 10.1021/Ja904391R |
0.588 |
|
| 2008 |
Crawford JM, Vagstad AL, Ehrlich KC, Udwary DW, Townsend CA. Acyl-carrier protein-phosphopantetheinyltransferase partnerships in fungal fatty acid synthases. Chembiochem : a European Journal of Chemical Biology. 9: 1559-63. PMID 18551496 DOI: 10.1002/Cbic.200700659 |
0.791 |
|
| 2008 |
Crawford JM, Thomas PM, Scheerer JR, Vagstad AL, Kelleher NL, Townsend CA. Deconstruction of iterative multidomain polyketide synthase function. Science (New York, N.Y.). 320: 243-6. PMID 18403714 DOI: 10.1126/Science.1154711 |
0.76 |
|
| 2008 |
Crawford JM, Vagstad AL, Whitworth KP, Ehrlich KC, Townsend CA. Synthetic strategy of nonreducing iterative polyketide synthases and the origin of the classical "starter-unit effect". Chembiochem : a European Journal of Chemical Biology. 9: 1019-23. PMID 18338425 DOI: 10.1002/Cbic.200700702 |
0.777 |
|
| 2008 |
Crawford JM, Vagstad AL, Ehrlich KC, Townsend CA. Starter unit specificity directs genome mining of polyketide synthase pathways in fungi. Bioorganic Chemistry. 36: 16-22. PMID 18215412 DOI: 10.1016/J.Bioorg.2007.11.002 |
0.785 |
|
| 2006 |
Crawford JM, Dancy BC, Hill EA, Udwary DW, Townsend CA. Identification of a starter unit acyl-carrier protein transacylase domain in an iterative type I polyketide synthase. Proceedings of the National Academy of Sciences of the United States of America. 103: 16728-33. PMID 17071746 DOI: 10.1073/Pnas.0604112103 |
0.793 |
|
| 2006 |
Townsend CA, Crawford JM, Bililign T. New images evoke FAScinating questions. Chemistry & Biology. 13: 349-51. PMID 16632247 DOI: 10.1016/J.Chembiol.2006.04.001 |
0.529 |
|
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