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David A. Spiegel, Ph.D., MD - Publications

Affiliations: 
2007- Chemistry Yale University, New Haven, CT 
Area:
natural product synthesis
Website:
http://www.chem.yale.edu/faculty/spiegel.html

118 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Douglass EF, Spiegel DA. Comment on a suite of mathematical solutions to describe ternary complex formation and their application to targeted protein degradation by heterobifunctional ligands. The Journal of Biological Chemistry. 296: 100331. PMID 33837728 DOI: 10.1016/j.jbc.2021.100331  1
2021 Jennings EQ, Ray JD, Zerio CJ, Trujillo MN, McDonald DM, Chapman E, Spiegel DA, Galligan J. Sirtuin 2 Regulates Protein LactoylLys Modifications. Chembiochem : a European Journal of Chemical Biology. PMID 33725370 DOI: 10.1002/cbic.202000883  1
2021 Rock CA, Keeney S, Zakharchenko A, Takano H, Spiegel DA, Krieger AM, Ferrari G, Levy RJ. Model studies of advanced glycation end product modification of heterograft biomaterials: The effects of in vitro glucose, glyoxal, and serum albumin on collagen structure and mechanical properties. Acta Biomaterialia. PMID 33444798 DOI: 10.1016/j.actbio.2020.12.053  1
2020 Streeter MD, Rowan S, Ray J, McDonald DM, Volkin J, Clark J, Taylor A, Spiegel DA. Generation and Characterization of Anti-Glucosepane Antibodies Enabling Direct Detection of Glucosepane in Retinal Tissue. Acs Chemical Biology. PMID 32975399 DOI: 10.1021/acschembio.0c00093  1
2020 Frasca A, Xue Y, Kossar AP, Keeney S, Rock C, Zakharchenko A, Streeter M, Gorman RC, Grau JB, George I, Bavaria JE, Krieger A, Spiegel DA, Levy RJ, Ferrari G. Glycation and Serum Albumin Infiltration Contribute to the Structural Degeneration of Bioprosthetic Heart Valves. Jacc. Basic to Translational Science. 5: 755-766. PMID 32875167 DOI: 10.1016/J.Jacbts.2020.06.008  1
2020 Fournier MN, Sinclair MR, Zheng ET, Spiegel DA, Johnson AL, S Shaw A, Riccio AI, Elliott ME, Bae DS, Sawyer JR. The Frequency of Mediastinal Injury in Acute Posterior Sternoclavicular Dislocations: A Multicenter Study. Journal of Pediatric Orthopedics. PMID 32804865 DOI: 10.1097/Bpo.0000000000001649  1
2020 Gautam S, Kim T, Howell R, Spiegel DA. Fluorescent stem peptide mimics: In situ probes for peptidoglycan crosslinking. Methods in Enzymology. 638: 57-67. PMID 32416921 DOI: 10.1016/Bs.Mie.2020.02.016  1
2020 Baldwin KD, Cahill PJ, Sponseller PD, Abel MF, Spiegel DA, Flynn JM, Pahys JM. BMI change following spinal fusion for neuromuscular scoliosis surgery. Spine Deformity. PMID 32394323 DOI: 10.1007/s43390-020-00109-1  1
2020 Stammers M, Ivanova IM, Niewczas IS, Segonds-Pichon A, Streeter M, Spiegel DA, Clark J. Age-related changes in the physical properties, cross-linking, and glycation of collagen from mouse tail tendon. The Journal of Biological Chemistry. PMID 32381510 DOI: 10.1074/Jbc.Ra119.011031  1
2020 Rowan S, Jiang S, Chang ML, Volkin J, Cassalman C, Smith KM, Streeter MD, Spiegel DA, Moreira-Neto C, Rabbani N, Thornalley PJ, Smith DE, Waheed NK, Taylor A. A low glycemic diet protects disease-prone Nrf2-deficient mice against age-related macular degeneration. Free Radical Biology & Medicine. PMID 32068111 DOI: 10.1016/J.Freeradbiomed.2020.02.010  1
2020 Al-Mahdi W, Ibrahim MM, Spiegel DA, Arkader A, Nance M, Baldwin K. Is Systemic Inflammatory Response Syndrome Relevant to Pulmonary Complications and Mortality in Multiply Injured Children? Journal of Pediatric Orthopedics. 40: 1-7. PMID 31815855 DOI: 10.1097/Bpo.0000000000001085  1
2019 De Coen R, Nuhn L, Perera C, Arista-Romero M, Risseeuw MDP, Freyn A, Nachbagauer R, Albertazzi L, Van Calenbergh S, Spiegel DA, Peterson BR, De Geest BG. A synthetic rhamnose glycopolymer cell surface receptor for endogenous antibody recruitment. Biomacromolecules. PMID 31829561 DOI: 10.1021/Acs.Biomac.9B01483  1
2019 Gaffney DO, Jennings EQ, Anderson CC, Marentette JO, Shi T, Schou Oxvig AM, Streeter MD, Johannsen M, Spiegel DA, Chapman E, Roede JR, Galligan JJ. Non-enzymatic Lysine Lactoylation of Glycolytic Enzymes. Cell Chemical Biology. PMID 31767537 DOI: 10.1016/J.Chembiol.2019.11.005  1
2019 Sabbasani VR, Wang KP, Streeter MD, Spiegel DA. One-Step Synthesis of 2,5-Diaminoimidazoles and Total Synthesis of Methylglyoxal-Derived Imidazolium Crosslink (MODIC). Angewandte Chemie (International Ed. in English). PMID 31713976 DOI: 10.1002/Anie.201911156  1
2019 Kolman SE, Ohara SY, Bhatia A, Feygin T, Colo D, Baldwin KD, Mcdonald-Mcginn D, Spiegel DA. The Clinical Utility of Flexion-extension Cervical Spine MRI in 22q11.2 Deletion Syndrome. Journal of Pediatric Orthopedics. 39: e674-e679. PMID 31503223 DOI: 10.1097/Bpo.0000000000000994  1
2019 Kim NY, Goddard TN, Sohn S, Spiegel DA, Crawford J. Biocatalytic Reversal of Advanced Glycation End Product Modification. Chembiochem : a European Journal of Chemical Biology. PMID 31013547 DOI: 10.1002/Cbic.201900158  1
2019 Refakis CA, Arkader A, Baldwin KD, Spiegel DA, Sankar WN. Predicting Periarticular Infection in Children With Septic Arthritis of the Hip: Regionally Derived Criteria May Not Apply to All Populations. Journal of Pediatric Orthopedics. 39: 268-274. PMID 30969258 DOI: 10.1097/Bpo.0000000000000934  1
2019 LeBrun DG, Banskota B, Banskota AK, Rajbhandari T, Baldwin KD, Spiegel DA. Erratum to: Socioeconomic Status Influences Functional Severity of Untreated Cerebral Palsy in Nepal: A Prospective Analysis and Systematic Review. Clinical Orthopaedics and Related Research. 477: 262-263. PMID 30586066 DOI: 10.1097/Corr.0000000000000553  1
2018 LeBrun DG, Del Rosario J, Kelly JD, Wren SM, Spiegel DA, Mkandawire N, Gosselin RA, Kushner AL. An Estimation of the Burden of Sports Injuries among African Adolescents. Journal of Epidemiology and Global Health. 8: 171-175. PMID 30864759 DOI: 10.2991/j.jegh.2017.10.010  1
2018 Banskota B, Yadav P, Rajbhandari T, Shrestha OP, Talwar D, Banskota A, Spiegel DA. Outcomes of the Ponseti Method for Untreated Clubfeet in Nepalese Patients Seen Between the Ages of One and Five Years and Followed for at Least 10 Years. The Journal of Bone and Joint Surgery. American Volume. 100: 2004-2014. PMID 30516623 DOI: 10.2106/JBJS.18.00445  1
2018 Anari JB, Arkader A, Spiegel DA, Baldwin KD. Approaching Unusual Pediatric Distal Humerus Fracture Patterns. The Journal of the American Academy of Orthopaedic Surgeons. PMID 30480586 DOI: 10.5435/JAAOS-D-17-00326  1
2018 Anari JB, Cahill PJ, Flynn JM, Spiegel DA, Baldwin KD. Intra-operative computed tomography guided navigation for pediatric pelvic instrumentation: A technique guide. World Journal of Orthopedics. 9: 185-189. PMID 30364843 DOI: 10.5312/Wjo.V9.I10.185  1
2018 Gautam S, Sharma L, Dela Cruz CS, Spiegel DA. A Slick Solution to a Sticky Problem. Biochemistry. PMID 30289246 DOI: 10.1021/Acs.Biochem.8B00916  1
2018 LeBrun DG, Banskota B, Banskota AK, Rajbhandari T, Baldwin KD, Spiegel DA. Socioeconomic Status Influences Functional Severity of Untreated Cerebral Palsy in Nepal: A Prospective Analysis and Systematic Review. Clinical Orthopaedics and Related Research. PMID 30179955 DOI: 10.1097/CORR.0000000000000476  1
2018 Galligan JJ, Wepy JA, Streeter MD, Kingsley PJ, Mitchener MM, Wauchope OR, Beavers WN, Rose KL, Wang T, Spiegel DA, Marnett LJ. Methylglyoxal-derived posttranslational arginine modifications are abundant histone marks. Proceedings of the National Academy of Sciences of the United States of America. PMID 30150385 DOI: 10.1016/J.Freeradbiomed.2018.10.362  1
2018 Kolman SE, Glanzman AM, Prosser L, Spiegel DA, Baldwin KD. Factors that Predict Overall Health and Quality of Life in Non-Ambulatory Individuals with Cerebral Palsy. The Iowa Orthopaedic Journal. 38: 147-152. PMID 30104938  1
2018 DeFrancesco CJ, Miller DJ, Cahill PJ, Spiegel DA, Flynn JM, Baldwin KD. Releasing the tether: Weight normalization following corrective spinal fusion in cerebral palsy. Journal of Orthopaedic Surgery (Hong Kong). 26: 2309499018782556. PMID 29938586 DOI: 10.1177/2309499018782556  1
2018 Premkumar A, Ying X, Mack Hardaker W, Massawe HH, Mshahaba DJ, Mandari F, Pallangyo A, Temu R, Masenga G, Spiegel DA, Sheth NP. Access to Orthopaedic Surgical Care in Northern Tanzania: A Modelling Study. World Journal of Surgery. PMID 29696326 DOI: 10.1007/s00268-018-4630-x  1
2017 Leung JC, Bedermann AA, Njardarson JT, Spiegel DA, Murphy GK, Hama N, Twenter BM, Dong P, Shirahata T, McDonald IM, Inoue M, Taniguchi N, McMahon TC, Schneider CM, Tao N, et al. Total Synthesis of (±)-Phomoidride D. Angewandte Chemie (International Ed. in English). PMID 29286556 DOI: 10.1002/Anie.201712369  1
2017 LeBrun DG, Talwar D, Pham TA, Banskota B, Spiegel DA. Predictors of healthcare seeking delays among children with chronic musculoskeletal disorders in Nepal. Journal of Epidemiology and Global Health. 7: 299-304. PMID 29110873 DOI: 10.1016/j.jegh.2017.10.002  1
2017 Al-Mahdi W, Ibrahim MM, Spiegel DA, Arkader A, Nance M, Baldwin K. Is Systemic Inflammatory Response Syndrome Relevant to Pulmonary Complications and Mortality in Multiply Injured Children? Journal of Pediatric Orthopedics. PMID 29016432 DOI: 10.1097/BPO.0000000000001085  1
2017 Nokin MJ, Durieux F, Bellier J, Peulen O, Uchida K, Spiegel DA, Cochrane JR, Hutton CA, Castronovo V, Bellahcène A. Hormetic potential of methylglyoxal, a side-product of glycolysis, in switching tumours from growth to death. Scientific Reports. 7: 11722. PMID 28916747 DOI: 10.1038/S41598-017-12119-7  1
2017 Ashley B, Spiegel DA, Cahill P, Talwar D, Baldwin KD. Post-operative fever in orthopaedic surgery: How effective is the 'fever workup?' Journal of Orthopaedic Surgery (Hong Kong). 25: 2309499017727953. PMID 28851265 DOI: 10.1177/2309499017727953  1
2017 Chirkin E, Muthusamy V, Mann P, Roemer T, Nantermet PG, Spiegel D. Neutralization of pathogenic fungi with small-molecule immunotherapeutics. Angewandte Chemie (International Ed. in English). PMID 28793176 DOI: 10.1002/Anie.201707536  0.56
2017 Mistovich RJ, Jacobs LJ, Campbell RM, Spiegel DA, Flynn JM, Baldwin KD. Infection Control in Pediatric Spinal Deformity Surgery: A Systematic and Critical Analysis Review. Jbjs Reviews. PMID 28514262 DOI: 10.2106/JBJS.RVW.16.00071  1
2017 Kolman SE, Ohara SY, Bhatia A, Feygin T, Colo D, Baldwin KD, Mcdonald-Mcginn D, Spiegel DA. The Clinical Utility of Flexion-Extension Cervical Spine MRI in 22q11.2 Deletion Syndrome. Journal of Pediatric Orthopedics. PMID 28441280 DOI: 10.1097/BPO.0000000000000994  1
2017 Vastl J, Wang T, Trinh TB, Spiegel DA. Encoded Silicon-Chip-Based Platform for Combinatorial Synthesis and Screening. Acs Combinatorial Science. PMID 28263558 DOI: 10.1021/Acscombsci.6B00181  1
2017 Refakis CA, Arkader A, Baldwin KD, Spiegel DA, Sankar WN. Predicting Periarticular Infection in Children With Septic Arthritis of the Hip: Regionally Derived Criteria May Not Apply to All Populations. Journal of Pediatric Orthopedics. PMID 28060181 DOI: 10.1097/BPO.0000000000000934  1
2016 Vastl J, Kartika R, Park K, Cho AE, Spiegel DA. Peptidines: glycine-amidine-based oligomers for solution- and solid-phase synthesis. Chemical Science. 7: 3317-3324. PMID 29997824 DOI: 10.1039/C5Sc03882K  1
2016 Nokin MJ, Durieux F, Peixoto P, Chiavarina B, Peulen O, Blomme A, Turtoi A, Costanza B, Smargiasso N, Baiwir D, Scheijen JL, Schalkwijk CG, Leenders J, De Tullio P, Bianchi E, ... ... Spiegel DA, et al. Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis. Elife. 5. PMID 27759563 DOI: 10.7554/Elife.19375  1
2016 Refakis CA, Baldwin KD, Spiegel DA, Sankar WN. Treatment of the Dislocated Hip in Infants With Spasticity. Journal of Pediatric Orthopedics. PMID 27379781 DOI: 10.1097/Bpo.0000000000000829  1
2016 Johnson RR, Friedman JM, Becker AM, Spiegel DA. The Ponseti Method for Clubfoot Treatment in Low and Middle-Income Countries: A Systematic Review of Barriers and Solutions to Service Delivery. Journal of Pediatric Orthopedics. PMID 26919713 DOI: 10.1097/BPO.0000000000000723  1
2016 Rullo AF, Fitzgerald KJ, Muthusamy V, Liu M, Yuan C, Huang M, Kim M, Cho AE, Spiegel DA. Re-engineering the Immune Response to Metastatic Cancer: Antibody-Recruiting Small Molecules Targeting the Urokinase Receptor. Angewandte Chemie (International Ed. in English). PMID 26879524 DOI: 10.1002/Anie.201510866  1
2015 Gray MA, Tao RN, DePorter SM, Spiegel DA, McNaughton B. A Nanobody Activation Immunotherapeutic That Selectively Destroys HER2-Positive Breast Cancer Cells. Chembiochem : a European Journal of Chemical Biology. PMID 26556305 DOI: 10.1002/Cbic.201500591  1
2015 Gautam S, Kim T, Lester E, Deep D, Spiegel DA. Wall teichoic acids prevent antibody binding to epitopes within the cell wall of Staphylococcus aureus. Acs Chemical Biology. PMID 26502318 DOI: 10.1021/Acschembio.5B00439  1
2015 Draghici C, Wang T, Spiegel DA. Concise total synthesis of glucosepane. Science (New York, N.Y.). 350: 294-8. PMID 26472902 DOI: 10.1126/Science.Aac9655  1
2015 Banskota B, Shrestha S, Rajbhandari T, Banskota AK, Spiegel DA. A Snapshot of 1001 Children Presenting with Cerebral Palsy to a Children's Disability Hospital. Journal of Nepal Health Research Council. 13: 31-7. PMID 26411710  1
2015 Gautam S, Kim T, Shoda T, Sen S, Deep D, Luthra R, Ferreira MT, Pinho MG, Spiegel DA. An Activity-Based Probe for Studying Crosslinking in Live Bacteria. Angewandte Chemie (International Ed. in English). PMID 26204841 DOI: 10.1002/Anie.201503869  1
2015 Shawar YR, Shiffman J, Spiegel DA. Generation of political priority for global surgery: a qualitative policy analysis. The Lancet. Global Health. 3: e487-95. PMID 26187491 DOI: 10.1016/S2214-109X(15)00098-4  1
2015 Dafre AL, Goldenberg J, Wang T, Spiegel DA, Maher P. Methylglyoxal, the foe and friend of glyoxalase and Trx/TrxR systems in HT22 nerve cells. Free Radical Biology & Medicine. PMID 26165190 DOI: 10.1016/J.Freeradbiomed.2015.07.005  1
2015 Wang T, Streeter MD, Spiegel DA. Generation and characterization of antibodies against arginine-derived advanced glycation endproducts. Bioorganic & Medicinal Chemistry Letters. PMID 26117561 DOI: 10.1016/J.Bmcl.2015.06.013  1
2015 Gautam S, Kim T, Spiegel DA. Chemical Probes Reveal an Extraseptal Mode of Cross-Linking in Staphylococcus aureus. Journal of the American Chemical Society. 137: 7441-7. PMID 26035224 DOI: 10.1021/Jacs.5B02972  1
2015 Kolman SE, Ruzbarsky JJ, Spiegel DA, Baldwin KD. Salvage Options in the Cerebral Palsy Hip: A Systematic Review. Journal of Pediatric Orthopedics. PMID 25887836 DOI: 10.1097/BPO.0000000000000501  1
2015 Dimitrievska S, Cai C, Weyers A, Balestrini JL, Lin T, Sundaram S, Hatachi G, Spiegel DA, Kyriakides TR, Miao J, Li G, Niklason LE, Linhardt RJ. Click-coated, heparinized, decellularized vascular grafts. Acta Biomaterialia. 13: 177-87. PMID 25463496 DOI: 10.1016/J.Actbio.2014.11.015  1
2014 McEnaney PJ, Fitzgerald KJ, Zhang AX, Douglass EF, Shan W, Balog A, Kolesnikova MD, Spiegel DA. Chemically synthesized molecules with the targeting and effector functions of antibodies. Journal of the American Chemical Society. 136: 18034-43. PMID 25514603 DOI: 10.1021/Ja509513C  1
2014 Parker CG, Dahlgren MK, Tao RN, Li DT, Douglass EF, Shoda T, Jawanda N, Spasov KA, Lee S, Zhou N, Domaoal RA, Sutton RE, Anderson KS, Jorgensen WL, Krystal M, ... Spiegel DA, et al. Illuminating HIV gp120-Ligand Recognition through Computationally-Driven Optimization of Antibody-Recruiting Molecules. Chemical Science (Royal Society of Chemistry : 2010). 5: 2311-2317. PMID 25379167 DOI: 10.1039/C4Sc00484A  1
2014 Gautam S, Spiegel DA. Pushing the Bacterial Envelope: Strategies for Re-Engineering Bacterial Surfaces with Heterologous Proteins and Sugars Micro-and Nanoengineering of the Cell Surface. 63-97. DOI: 10.1016/B978-1-4557-3146-6.00004-0  1
2014 Gosselin RA, Spiegel DA, Foltz M. What do we call this place? Global Orthopedics: Caring For Musculoskeletal Conditions and Injuries in Austere Settings. xi-xii. DOI: 10.1007/978-1-4614-1578-7  1
2013 Perry RJ, Kim T, Zhang XM, Lee HY, Pesta D, Popov VB, Zhang D, Rahimi Y, Jurczak MJ, Cline GW, Spiegel DA, Shulman GI. Reversal of hypertriglyceridemia, fatty liver disease, and insulin resistance by a liver-targeted mitochondrial uncoupler. Cell Metabolism. 18: 740-8. PMID 24206666 DOI: 10.1016/J.Cmet.2013.10.004  1
2013 Jakobsche CE, Parker CG, Tao RN, Kolesnikova MD, Douglass EF, Spiegel DA. Exploring binding and effector functions of natural human antibodies using synthetic immunomodulators. Acs Chemical Biology. 8: 2404-11. PMID 24053626 DOI: 10.1021/Cb4004942  1
2013 Wang T, Douglass EF, Fitzgerald KJ, Spiegel DA. A "turn-on" fluorescent sensor for methylglyoxal. Journal of the American Chemical Society. 135: 12429-33. PMID 23931147 DOI: 10.1021/Ja406077J  1
2013 Spiegel DA. A call to ARMs: the promise of immunomodulatory small molecules. Expert Review of Clinical Pharmacology. 6: 223-5. PMID 23656334 DOI: 10.1586/Ecp.13.10  1
2013 Douglass EF, Miller CJ, Sparer G, Shapiro H, Spiegel DA. A comprehensive mathematical model for three-body binding equilibria. Journal of the American Chemical Society. 135: 6092-9. PMID 23544844 DOI: 10.1021/Ja311795D  1
2013 Gautam S, Gniadek TJ, Kim T, Spiegel DA. Exterior design: strategies for redecorating the bacterial surface with small molecules. Trends in Biotechnology. 31: 258-67. PMID 23490213 DOI: 10.1016/J.Tibtech.2013.01.012  1
2013 Murphy GK, Shirahata T, Hama N, Bedermann A, Dong P, McMahon TC, Twenter BM, Spiegel DA, McDonald IM, Taniguchi N, Inoue M, Wood JL. Toward the synthesis of phomoidride D. The Journal of Organic Chemistry. 78: 477-89. PMID 23245580 DOI: 10.1021/Jo302353G  1
2013 Kim T, Spiegel DA. The unique reactivity of N-phenacyl-derived thiazolium salts toward α-dicarbonyl compounds. Rejuvenation Research. 16: 43-50. PMID 23186164 DOI: 10.1089/Rej.2012.1370  1
2013 Kim T, Spiegel DA. Serendipitous discovery of two highly selective inhibitors of bacterial luciferase This work is dedicated to Professor Paul Wender, with recognition and gratitude for his inspirational contributions to scientific research and discovery Tetrahedron. 69: 7692-7698. DOI: 10.1016/J.Tet.2013.05.086  1
2012 Murphy GK, Hama N, Bedermann A, Dong P, Schneider CM, McMahon TC, Tao RN, Twenter BM, Spiegel DA, Wood JL. Wharton-fragmentation-based approach to the carbocyclic core of the phomoidrides. Organic Letters. 14: 4544-7. PMID 22917221 DOI: 10.1021/Ol302011B  1
2012 McEnaney PJ, Parker CG, Zhang AX, Spiegel DA. Antibody-recruiting molecules: an emerging paradigm for engaging immune function in treating human disease. Acs Chemical Biology. 7: 1139-51. PMID 22758917 DOI: 10.1021/Cb300119G  1
2012 Morissette SB, Gulliver SB, Kamholz BW, Spiegel DA, Tiffany ST, Barlow DH. Transdermal nicotine during cue reactivity in adult smokers with and without anxiety disorders. Psychology of Addictive Behaviors : Journal of the Society of Psychologists in Addictive Behaviors. 26: 507-18. PMID 22686966 DOI: 10.1037/A0028828  1
2012 Wang T, Kartika R, Spiegel DA. Exploring post-translational arginine modification using chemically synthesized methylglyoxal hydroimidazolones. Journal of the American Chemical Society. 134: 8958-67. PMID 22591136 DOI: 10.1021/Ja301994D  1
2012 Jakobsche CE, McEnaney PJ, Zhang AX, Spiegel DA. Reprogramming urokinase into an antibody-recruiting anticancer agent. Acs Chemical Biology. 7: 316-21. PMID 22098560 DOI: 10.1021/cb200374e  1
2011 Dubrovska A, Kim C, Elliott J, Shen W, Kuo TH, Koo DI, Li C, Tuntland T, Chang J, Groessl T, Wu X, Gorney V, Ramirez-Montagut T, Spiegel DA, Cho CY, et al. A chemically induced vaccine strategy for prostate cancer. Acs Chemical Biology. 6: 1223-31. PMID 21936526 DOI: 10.1021/Cb200222S  1
2011 Hendrickson JE, Hod EA, Cadwell CM, Eisenbarth SC, Spiegel DA, Tormey CA, Spitalnik SL, Zimring JC. Rapid clearance of transfused murine red blood cells is associated with recipient cytokine storm and enhanced alloimmunogenicity. Transfusion. 51: 2445-54. PMID 21569043 DOI: 10.1111/J.1537-2995.2011.03162.X  1
2010 Spiegel DA. Grand challenge commentary: Synthetic immunology to engineer human immunity. Nature Chemical Biology. 6: 871-2. PMID 21079593 DOI: 10.1038/Nchembio.477  1
2010 Nelson JW, Chamessian AG, McEnaney PJ, Murelli RP, Kazmierczak BI, Kazmiercak BI, Spiegel DA. A biosynthetic strategy for re-engineering the Staphylococcus aureus cell wall with non-native small molecules. Acs Chemical Biology. 5: 1147-55. PMID 20923200 DOI: 10.1021/Cb100195D  1
2010 Zhang AX, Murelli RP, Barinka C, Michel J, Cocleaza A, Jorgensen WL, Lubkowski J, Spiegel DA. A remote arene-binding site on prostate specific membrane antigen revealed by antibody-recruiting small molecules. Journal of the American Chemical Society. 132: 12711-6. PMID 20726553 DOI: 10.1021/Ja104591M  1
2009 Stern E, Jay SM, Demento SL, Murelli RP, Reed MA, Malinski T, Spiegel DA, Mooney DJ, Fahmy TM. Spatiotemporal control over molecular delivery and cellular encapsulation from electropolymerized micro- and nanopatterned surfaces. Advanced Functional Materials. 19: 2888-2895. PMID 20445826 DOI: 10.1002/Adfm.200900307  1
2009 Murelli RP, Zhang AX, Michel J, Jorgensen WL, Spiegel DA. Chemical control over immune recognition: a class of antibody-recruiting small molecules that target prostate cancer. Journal of the American Chemical Society. 131: 17090-2. PMID 19888723 DOI: 10.1021/Ja906844E  1
2009 Parker CG, Domaoal RA, Anderson KS, Spiegel DA. An antibody-recruiting small molecule that targets HIV gp120. Journal of the American Chemical Society. 131: 16392-4. PMID 19839582 DOI: 10.1021/Ja9057647  1
2008 Bitran S, Morissette SB, Spiegel DA, Barlow DH. A pilot study of sensation-focused intensive treatment for panic disorder with moderate to severe agoraphobia: preliminary outcome and benchmarking data. Behavior Modification. 32: 196-214. PMID 18285506 DOI: 10.1177/0145445507309019  1
2008 Morissette SB, Spiegel DA, Barlow DH. Combining exposure and pharmacotherapy in the treatment of social anxiety disorder: A preliminary study of state dependent learning Journal of Psychopathology and Behavioral Assessment. 30: 211-219. DOI: 10.1007/S10862-007-9061-1  1
2008 Heinrichs N, Spiegel DA, Hofmann SG. Panic Disorder with Agoraphobia Handbook of Brief Cognitive Behaviour Therapy. 55-76. DOI: 10.1002/9780470713020.ch4  1
2007 Medeiros MR, Schacherer LN, Spiegel DA, Wood JL. Expanding the scope of trialkylborane/water-mediated radical reactions. Organic Letters. 9: 4427-9. PMID 17900194 DOI: 10.1021/Ol7016609  1
2007 Horn DB, Spiegel DA. Orthopedics Comprehensive Pediatric Hospital Medicine. 919-923. DOI: 10.1016/B978-032303004-5.50149-6  1
2006 Spiegel DA, Schroeder FC, Duvall JR, Schreiber SL. An oligomer-based approach to skeletal diversity in small-molecule synthesis. Journal of the American Chemical Society. 128: 14766-7. PMID 17105261 DOI: 10.1021/Ja065724A  1
2005 Spiegel DA, Wiberg KB, Schacherer LN, Medeiros MR, Wood JL. Deoxygenation of alcohols employing water as the hydrogen atom source. Journal of the American Chemical Society. 127: 12513-5. PMID 16144398 DOI: 10.1021/Ja052185L  1
2005 Morissette SB, Palfai TP, Gulliver SB, Spiegel DA, Barlow DH. Effects of transdermal nicotine during imaginal exposure to anxiety and smoking cues in college smokers. Psychology of Addictive Behaviors : Journal of the Society of Psychologists in Addictive Behaviors. 19: 192-8. PMID 16011390 DOI: 10.1037/0893-164X.19.2.192  1
2005 Morissette SB, Spiegel DA, Heinrichs N. Sensation-focused intensive treatment for panic disorder with moderate to severe agoraphobia Cognitive and Behavioral Practice. 12: 17-29. DOI: 10.1016/S1077-7229(05)80036-7  1
2003 Spiegel DA, Njardarson JT, McDonald IM, Wood JL. The art of innovation in organic chemistry: synthetic efforts toward the phomoidrides. Chemical Reviews. 103: 2691-727. PMID 12848583 DOI: 10.1021/Cr020408+  1
2002 Houck PR, Spiegel DA, Shear MK, Rucci P. Reliability of the self-report version of the panic disorder severity scale. Depression and Anxiety. 15: 183-5. PMID 12112724 DOI: 10.1002/da.10049  1
2002 Spiegel DA, Njardarson JT, Wood JL. CP-263,114 synthetic studies. Construction of an isotwistane ring system via rhodium carbenoid C-H insertion Tetrahedron. 58: 6545-6554. DOI: 10.1016/S0040-4020(02)00664-6  1
2001 Njardarson JT, McDonald IM, Spiegel DA, Inoue M, Wood JL. An expeditious approach toward the total synthesis of CP-263,114. Organic Letters. 3: 2435-8. PMID 11483028 DOI: 10.1021/Ol015979N  1
1999 Spiegel DA. Psychological strategies for discontinuing benzodiazepine treatment. Journal of Clinical Psychopharmacology. 19: 17S-22S. PMID 10587280 DOI: 10.1097/00004714-199912002-00004  1
1999 Bruce TJ, Spiegel DA, Hegel MT. Cognitive-behavioral therapy helps prevent relapse and recurrence of panic disorder following alprazolam discontinuation: a long-term follow-up of the Peoria and Dartmouth studies. Journal of Consulting and Clinical Psychology. 67: 151-6. PMID 10028220 DOI: 10.1037/0022-006X.67.1.151  1
1999 Hofmann SG, Spiegel DA. Panic control treatment and its applications. The Journal of Psychotherapy Practice and Research. 8: 3-11. PMID 9888103  1
1998 Spiegel DA. Efficacy studies of alprazolam in panic disorder. Psychopharmacology Bulletin. 34: 191-5. PMID 9640999  1
1997 Spiegel DA, Bruce TJ. Benzodiazepines and exposure-based cognitive behavior therapies for panic disorder: conclusions from combined treatment trials. The American Journal of Psychiatry. 154: 773-81. PMID 9167504  1
1996 Spiegel DA, Saeed SA, Bruce TJ. An open trial of fluvoxamine therapy for panic disorder complicated by depression. The Journal of Clinical Psychiatry. 57: 37-40; discussion 40. PMID 8698679  1
1995 Bruce TJ, Spiegel DA, Gregg SF, Nuzzarello A. Predictors of alprazolam discontinuation with and without cognitive behavior therapy in panic disorder. The American Journal of Psychiatry. 152: 1156-60. PMID 7625463  1
1994 Spiegel DA, Bruce TJ, Gregg SF, Nuzzarello A. Does cognitive behavior therapy assist slow-taper alprazolam discontinuation in panic disorder? The American Journal of Psychiatry. 151: 876-81. PMID 8184997  1
1993 Spiegel DA, Seaber AV, Chen LE, Urbaniak JR. Recovery following stretch injury to the sciatic nerve of the rat: an in vivo study. Journal of Reconstructive Microsurgery. 9: 69-74. PMID 8423563 DOI: 10.1055/s-2007-1006641  1
1993 Spiegel DA, Roth M, Weissman M, Lavori P, Gorman J, Rush J, Ballenger J. Comment on the London/Toronto Study of Alprazolam and Exposure in Panic Disorder with Agoraphobia. The British Journal of Psychiatry : the Journal of Mental Science. 162: 788-9; discussion 79. PMID 8101127 DOI: 10.1192/Bjp.162.6.788  1
1992 Sotereanos DG, Seaber AV, Urbaniak JR, Spiegel DA, Sotereanos D, Anthony DC. Reversing nerve-graft polarity in a rat model: the effect on function. Journal of Reconstructive Microsurgery. 8: 303-7. PMID 1629808 DOI: 10.1055/S-2007-1006712  1
1992 Spiegel DA, Dexter F, Warner DS, Baker MT, Todd MM. Central nervous system toxicity of local anesthetic mixtures in the rat. Anesthesia and Analgesia. 75: 922-8. PMID 1443711  1
1991 Ahles TA, Khan SA, Yunus MB, Spiegel DA, Masi AT. Psychiatric status of patients with primary fibromyalgia, patients with rheumatoid arthritis, and subjects without pain: a blind comparison of DSM-III diagnoses. The American Journal of Psychiatry. 148: 1721-6. PMID 1957937 DOI: 10.1176/Ajp.148.12.1721  1
1990 Spiegel DA, Seaber AV, Urbaniak JR. The effects of betamethasone following stretch injury to the sciatic nerve of the rat Surgical Forum. 41: 525-527.  1
1987 Spiegel DA, Smolen RC, Hopfensperger KA. Interpersonal stress in medical education: correlates for men and women students. Journal of the American Medical Women's Association (1972). 42: 19-21. PMID 3819276  1
1987 Khan SA, Spiegel DA, Jobe PC. Psychotomimetic effects of anorectic drugs. American Family Physician. 36: 107-12. PMID 3618447  1
1987 Smolen RC, Spiegel DA. Marital locus of control as a modifier of the relationship between the frequency of provocation by spouse and marital satisfaction Journal of Research in Personality. 21: 70-80. DOI: 10.1016/0092-6566(87)90027-4  1
1986 Spiegel DA, Smolen RC, Jonas CK. An examination of the relationships among interpersonal stress, morale and academic performance in male and female medical students. Social Science & Medicine (1982). 23: 1157-61. PMID 3810201 DOI: 10.1016/0277-9536(86)90334-5  1
1986 Smolen RC, Spiegel DA, Martin CJ. Patterns of marital interaction associated with marital dissatisfaction and depression. Journal of Behavior Therapy and Experimental Psychiatry. 17: 261-6. PMID 3805310 DOI: 10.1016/0005-7916(86)90061-3  1
1986 Spiegel DA, Smolen RC, Hopfensperger KA. Medical student stress and clerkship performance. Journal of Medical Education. 61: 929-31. PMID 3772973  1
1985 Spiegel DA, Smolen RC, Jonas CK. Interpersonal conflicts involving students in clinical medical education. Journal of Medical Education. 60: 819-29. PMID 4057223  1
1985 Smolen RC, Spiegel DA, Bakker-Rabdau MK, Bakker CB, Martin C. A situational analysis of the relationship between spouse-specific assertiveness and marital adjustment Journal of Psychopathology and Behavioral Assessment. 7: 397-410. DOI: 10.1007/BF00960712  1
1981 Spiegel DA. Motivating the student in the psychiatry clerkship. Journal of Medical Education. 56: 593-600. PMID 7241558  1
1977 Hokin-Neaverson M, Spiegel DA, Burckhardt WA, Jefferson JW. Age and sex differences of erythrocyte sodium pump activity in normal human subjects. Clinica Chimica Acta; International Journal of Clinical Chemistry. 76: 399-401. PMID 858208  1
1974 Hokin-Neaverson M, Spiegel DA, Lewis WC. Deficiency of erythrocyte sodium pump activity in bipolar manic-depressive psychosis. Life Sciences. 15: 1739-48. PMID 4620986  1
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