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Thomas Sommer - Publications

Affiliations: 
Max-Delbrück-Center for Molecular Medicine Friedrich-Wilhelms-Universität zu Berlin, Berlin, Prussia, Germany 
Area:
Intracellular Proteolysis
Website:
https://www.mdc-berlin.de/34803758/de/phd_ausbildung/phd_program/People/Faculty/Faculty_info/Research_Groups/Sommer

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Christianson JC, Jarosch E, Sommer T. Mechanisms of substrate processing during ER-associated protein degradation. Nature Reviews. Molecular Cell Biology. PMID 37528230 DOI: 10.1038/s41580-023-00633-8  0.408
2022 Brodsky JL, Engelman DM, Hendershot LM, Piana-Agostinetti S, Sommer T. Taking out the trash: How misfolded proteins are removed from the endoplasmic reticulum. Faculty Reviews. 11: 29. PMID 36267301 DOI: 10.12703/r-01-0000018  0.337
2016 Pfeiffer A, Stephanowitz H, Krause E, Volkwein C, Hirsch C, Jarosch E, Sommer T. A complex of Htm1 and the oxidoreductase Pdi1 accelerates degradation of misfolded glycoproteins. The Journal of Biological Chemistry. PMID 27053108 DOI: 10.1074/jbc.M115.703256  0.336
2015 Mehnert M, Sommermeyer F, Berger M, Kumar Lakshmipathy S, Gauss R, Aebi M, Jarosch E, Sommer T. The interplay of Hrd3 and the molecular chaperone system ensures efficient degradation of malfolded secretory proteins. Molecular Biology of the Cell. 26: 185-94. PMID 25428985 DOI: 10.1091/Mbc.E14-07-1202  0.398
2014 Mehnert M, Sommer T, Jarosch E. Der1 promotes movement of misfolded proteins through the endoplasmic reticulum membrane. Nature Cell Biology. 16: 77-86. PMID 24292014 DOI: 10.1038/ncb2882  0.382
2012 Hampton RY, Sommer T. Finding the will and the way of ERAD substrate retrotranslocation. Current Opinion in Cell Biology. 24: 460-6. PMID 22854296 DOI: 10.1016/J.Ceb.2012.05.010  0.393
2011 Bagola K, Mehnert M, Jarosch E, Sommer T. Protein dislocation from the ER. Biochimica Et Biophysica Acta. 1808: 925-36. PMID 20599420 DOI: 10.1016/j.bbamem.2010.06.025  0.375
2010 Mehnert M, Sommer T, Jarosch E. ERAD ubiquitin ligases: multifunctional tools for protein quality control and waste disposal in the endoplasmic reticulum. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 32: 905-13. PMID 20806269 DOI: 10.1002/bies.201000046  0.42
2009 Horn SC, Hanna J, Hirsch C, Volkwein C, Schütz A, Heinemann U, Sommer T, Jarosch E. Usa1 functions as a scaffold of the HRD-ubiquitin ligase. Molecular Cell. 36: 782-93. PMID 20005842 DOI: 10.1016/j.molcel.2009.10.015  0.368
2009 Clerc S, Hirsch C, Oggier DM, Deprez P, Jakob C, Sommer T, Aebi M. Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum. The Journal of Cell Biology. 184: 159-72. PMID 19124653 DOI: 10.1083/Jcb.200809198  0.323
2006 Gauss R, Sommer T, Jarosch E. The Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitment. The Embo Journal. 25: 1827-35. PMID 16619026 DOI: 10.1038/sj.emboj.7601088  0.404
2005 Neuber O, Jarosch E, Volkwein C, Walter J, Sommer T. Ubx2 links the Cdc48 complex to ER-associated protein degradation. Nature Cell Biology. 7: 993-8. PMID 16179953 DOI: 10.1038/ncb1298  0.411
2005 Meusser B, Hirsch C, Jarosch E, Sommer T. ERAD: the long road to destruction. Nature Cell Biology. 7: 766-72. PMID 16056268 DOI: 10.1038/ncb0805-766  0.326
2004 Hirsch C, Jarosch E, Sommer T, Wolf DH. Endoplasmic reticulum-associated protein degradation--one model fits all? Biochimica Et Biophysica Acta. 1695: 215-23. PMID 15571817 DOI: 10.1016/J.Bbamcr.2004.10.006  0.365
2004 Meusser B, Sommer T. Vpu-mediated degradation of CD4 reconstituted in yeast reveals mechanistic differences to cellular ER-associated protein degradation. Molecular Cell. 14: 247-58. PMID 15099523 DOI: 10.1016/S1097-2765(04)00212-6  0.305
2003 Jarosch E, Lenk U, Sommer T. Endoplasmic reticulum-associated protein degradation. International Review of Cytology. 223: 39-81. PMID 12641210 DOI: 10.1016/S0074-7696(05)23002-4  0.383
2002 Stade K, Vogel F, Schwienhorst I, Meusser B, Volkwein C, Nentwig B, Dohmen RJ, Sommer T. A lack of SUMO conjugation affects cNLS-dependent nuclear protein import in yeast. The Journal of Biological Chemistry. 277: 49554-61. PMID 12393908 DOI: 10.1074/jbc.M207991200  0.315
2002 Jarosch E, Geiss-Friedlander R, Meusser B, Walter J, Sommer T. Protein dislocation from the endoplasmic reticulum--pulling out the suspect. Traffic (Copenhagen, Denmark). 3: 530-6. PMID 12121416 DOI: 10.1034/j.1600-0854.2002.30803.x  0.338
2002 Lenk U, Yu H, Walter J, Gelman MS, Hartmann E, Kopito RR, Sommer T. A role for mammalian Ubc6 homologues in ER-associated protein degradation. Journal of Cell Science. 115: 3007-14. PMID 12082160  0.433
2002 Jarosch E, Taxis C, Volkwein C, Bordallo J, Finley D, Wolf DH, Sommer T. Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48. Nature Cell Biology. 4: 134-9. PMID 11813000 DOI: 10.1038/Ncb746  0.387
2001 Walter J, Urban J, Volkwein C, Sommer T. Sec61p-independent degradation of the tail-anchored ER membrane protein Ubc6p. The Embo Journal. 20: 3124-31. PMID 11406589 DOI: 10.1093/emboj/20.12.3124  0.427
2000 Lenk U, Sommer T. Ubiquitin-mediated proteolysis of a short-lived regulatory protein depends on its cellular localization. The Journal of Biological Chemistry. 275: 39403-10. PMID 10991948 DOI: 10.1074/jbc.M006949200  0.341
2000 Friedlander R, Jarosch E, Urban J, Volkwein C, Sommer T. A regulatory link between ER-associated protein degradation and the unfolded-protein response. Nature Cell Biology. 2: 379-84. PMID 10878801 DOI: 10.1038/35017001  0.333
1997 Sommer T, Wolf DH. Endoplasmic reticulum degradation: reverse protein flow of no return. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 11: 1227-33. PMID 9409541 DOI: 10.1096/Fasebj.11.14.9409541  0.427
1997 Biederer T, Volkwein C, Sommer T. Role of Cue1p in ubiquitination and degradation at the ER surface. Science (New York, N.Y.). 278: 1806-9. PMID 9388185 DOI: 10.1126/science.278.5344.1806  0.554
1997 Plemper RK, Böhmler S, Bordallo J, Sommer T, Wolf DH. Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation. Nature. 388: 891-5. PMID 9278052 DOI: 10.1038/42276  0.319
1996 Biederer T, Volkwein C, Sommer T. Degradation of subunits of the Sec61p complex, an integral component of the ER membrane, by the ubiquitin-proteasome pathway. The Embo Journal. 15: 2069-76. PMID 8641272 DOI: 10.1002/J.1460-2075.1996.Tb00560.X  0.553
1994 Hartmann E, Sommer T, Prehn S, Görlich D, Jentsch S, Rapoport TA. Evolutionary conservation of components of the protein translocation complex. Nature. 367: 654-7. PMID 8107851 DOI: 10.1038/367654A0  0.303
1993 Sommer T, Jentsch S. A protein translocation defect linked to ubiquitin conjugation at the endoplasmic reticulum. Nature. 365: 176-9. PMID 8396728 DOI: 10.1038/365176A0  0.409
1992 Sommer T, Seufert W. Genetic analysis of ubiquitin-dependent protein degradation. Experientia. 48: 172-8. PMID 1740189 DOI: 10.1007/BF01923510  0.342
1990 Jentsch S, Seufert W, Sommer T, Reins HA. Ubiquitin-conjugating enzymes: novel regulators of eukaryotic cells. Trends in Biochemical Sciences. 15: 195-8. PMID 2193438 DOI: 10.1016/0968-0004(90)90161-4  0.357
1989 Sommer T, Chambers JA, Eberle J, Lauter FR, Russo VE. Fast light-regulated genes of Neurospora crassa. Nucleic Acids Research. 17: 5713-23. PMID 2527354 DOI: 10.1093/Nar/17.14.5713  0.391
1987 Sommer T, Degli-Innocenti F, Russo VE. Role of nitrogen in the photoinduction of protoperithecia and carotenoids in Neurospora crassa. Planta. 170: 205-8. PMID 24232879 DOI: 10.1007/Bf00397889  0.324
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