Susan G. Brown - Related publications

Affiliations: 
2013 Chemistry University of Minnesota, Twin Cities, Minneapolis, MN 
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Sherbiny FF, Bayoumi AH, El-Morsy AM, Sobhy M, Hagras M. Design, Synthesis, biological Evaluation, and molecular docking studies of novel Pyrazolo[3,4-d]Pyrimidine derivative scaffolds as potent EGFR inhibitors and cell apoptosis inducers. Bioorganic Chemistry. 116: 105325. PMID 34507234 DOI: 10.1016/j.bioorg.2021.105325   
2021 Delbart DI, Giri GF, Cammarata A, Bareño LA, Amigo NL, Bechis A, Suarez AG, Spanevello RÁ, Todaro LB, Urtreger AJ. Antineoplastic activity of products derived from cellulose-containing materials: levoglucosenone and structurally-related derivatives as new alternatives for breast cancer treatment. Investigational New Drugs. PMID 34478029 DOI: 10.1007/s10637-021-01167-6   
2021 Pham NKT, Nguyen TDH, Nguyen TMC, Nguyen GD, Huynh CD, Vo TN, Nguyen TQT, Duong TH, Dang VS, Huynh BLC, Tran TNM, Nguyen TP. Lasibidoupins A and B, two new compounds from the stems of V.S. Dang & Naiki. Natural Product Research. 1-7. PMID 34542362 DOI: 10.1080/14786419.2021.1979545   
2021 Elhady SS, Abdelhameed RFA, Zekry SH, Ibrahim AK, Habib ES, Darwish KM, Hazem RM, Mohammad KA, Hassanean HA, Ahmed SA. VEGFR-Mediated Cytotoxic Activity of Isolated Metabolites: A Biological Evaluation and In Silico Study. Life (Basel, Switzerland). 11. PMID 34440504 DOI: 10.3390/life11080759   
2021 Pérez-Villanueva J, Matadamas-Martínez F, Yépez-Mulia L, Pérez-Koldenkova V, Leyte-Lugo M, Rodríguez-Villar K, Cortés-Benítez F, Macías-Jiménez AP, González-Sánchez I, Romero-Velásquez A, Palacios-Espinosa JF, Soria-Arteche O. Synthesis and Cytotoxic Activity of Combretastatin A-4 and 2,3-Diphenyl-2-indazole Hybrids. Pharmaceuticals (Basel, Switzerland). 14. PMID 34451912 DOI: 10.3390/ph14080815   
2021 Yan J, Xu Y, Jin X, Zhang Q, Ouyang F, Han L, Zhan M, Li X, Liang B, Huang X. Structure modification and biological evaluation of indole-chalcone derivatives as anti-tumor agents through dual targeting tubulin and TrxR. European Journal of Medicinal Chemistry. 227: 113897. PMID 34649064 DOI: 10.1016/j.ejmech.2021.113897   
2021 Pellissier L, Koval A, Marcourt L, Ferreira Queiroz E, Lecoultre N, Leoni S, Quiros-Guerrero LM, Barthélémy M, Duivelshof BL, Guillarme D, Tardy S, Eparvier V, Perron K, Chave J, Stien D, et al. Isolation and Identification of Isocoumarin Derivatives With Specific Inhibitory Activity Against Wnt Pathway and Metabolome Characterization of . Frontiers in Chemistry. 9: 664489. PMID 34458231 DOI: 10.3389/fchem.2021.664489   
2021 Yang BJ, Wang J, Zeng ZQ, Yang X, Huang AY, Hao XJ, Ding X, Li SL. Sesquiterpene lactones from L. and their activity in inducing protective autophagy. Natural Product Research. 1-4. PMID 34498970 DOI: 10.1080/14786419.2021.1955881   
2021 Ii H, Nohara Y, Yoshiya T, Masuda S, Tsuda S, Oishi S, Friedman J, Kawabe T, Nakata S. Identification of U83836E as a γ-glutamylcyclotransferase inhibitor that suppresses MCF7 breast cancer xenograft growth. Biochemical and Biophysical Research Communications. 549: 128-134. PMID 33676180 DOI: 10.1016/j.bbrc.2021.02.103   
2021 Han X, Song N, Saidahmatov A, Wang P, Wang Y, Hu X, Kan W, Zhu W, Gao L, Zeng M, Wang Y, Li C, Li J, Liu H, Zhou Y, et al. Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia. Journal of Medicinal Chemistry. PMID 34477384 DOI: 10.1021/acs.jmedchem.1c01148   
2021 Giang VH, Thuy LT, Cham PT, Vinh LB, Ban NK, Linh TM, Mai NC, Hoe PT, Huong TT, Dang NH, Oh H, Quang TH. Chemical constituents from and their anti-inflammatory and cytotoxic activities. Natural Product Research. 1-7. PMID 34498971 DOI: 10.1080/14786419.2021.1958807   
2021 El Azab IH, Saied EM, Osman AA, Mehana AE, Saad HA, Elkanzi NA. Novel -bridged pyrazole-1-carbothioamides with potential antiproliferative activity: design, synthesis, and studies. Future Medicinal Chemistry. PMID 34427113 DOI: 10.4155/fmc-2021-0066   
2021 Tavares FM, Gomes AC, Assunção EM, de Medeiros JLS, Scotti MT, Scotti L, Ishiki HM. Virtual Screening and Molecular Docking: Discovering Novel c-KIT Inhibitors. Current Medicinal Chemistry. PMID 34525909 DOI: 10.2174/0929867328666210915102920   
2021 Pathak A, Pandey V, Raj Pokharel Y, Devaraji V, Ali A, Haider K, Saad S, Dewangan RP, Siddiqui N, Shahar Yar M. Pharmacophore based drug design and synthesis of oxindole bearing hybrid as anticancer agents. Bioorganic Chemistry. 116: 105358. PMID 34544029 DOI: 10.1016/j.bioorg.2021.105358   
2021 Islam MK, Baek AR, Sung B, Yang BW, Choi G, Park HJ, Kim YH, Kim M, Ha S, Lee GH, Kim HK, Chang Y. Synthesis, Characterization, and Anticancer Activity of Benzothiazole Aniline Derivatives and Their Platinum (II) Complexes as New Chemotherapy Agents. Pharmaceuticals (Basel, Switzerland). 14. PMID 34451928 DOI: 10.3390/ph14080832   
2021 Hayat K, Tariq U, Wong QA, Quah CK, Majid ASA, Nazari V M, Ahamed MBK, Iqbal MA, Tirmizi SA. Green synthesis of selenium based N-heterocyclic carbene compounds; structural, in-vitro anticancer and molecular docking studies. Computational Biology and Chemistry. 94: 107567. PMID 34500323 DOI: 10.1016/j.compbiolchem.2021.107567   
2021 Yuan P, Gu X, Ni X, Qi Y, Shao X, Xu X, Liu J, Qian X. Non-alkylator anti-glioblastoma agents induced cell cycle G2/M arrest and apoptosis:Design, In silico physicochemical and SAR Studies of 2-Aminoquinoline-3-carboxamides. Bioorganic & Medicinal Chemistry Letters. 128371. PMID 34534673 DOI: 10.1016/j.bmcl.2021.128371   
2021 Emam AM, Dahal A, Singh SS, Tosso RD, Ibrahim SM, El-Sadek M, Jois SD, Enriz RD, Kothayer H. Quinazoline-tethered hydrazone: A versatile scaffold toward dual anti-TB and EGFR inhibition activities in NSCLC. Archiv Der Pharmazie. e2100281. PMID 34585758 DOI: 10.1002/ardp.202100281   
2021 Ali A, Ali A, Tahir A, Bakht MA, Salahuddin, Ahsan MJ. Molecular Engineering of Curcumin, an Active Constituent of L. (Turmeric) of the Family with Improved Antiproliferative Activity. Plants (Basel, Switzerland). 10. PMID 34451604 DOI: 10.3390/plants10081559   
2021 Zhang D, Hu Y, Hao Z, Zhang Y, Luo S, Dang X, Sun R, Duan S, Lv D, Jiang F, Fu L. Design, synthesis and antitumor activities of thiazole-containing mitochondrial targeting agents. Bioorganic Chemistry. 115: 105271. PMID 34426155 DOI: 10.1016/j.bioorg.2021.105271   
2021 Onder FC, Durdagi S, Kahraman N, Uslu TN, Kandemir H, Atici EB, Ozpolat B, Ay M. Novel inhibitors of eukaryotic elongation factor 2 kinase: In silico, synthesis and in vitro studies. Bioorganic Chemistry. 116: 105296. PMID 34488125 DOI: 10.1016/j.bioorg.2021.105296   
2021 KalantarMotamedi Y, Choi RJ, Koh SB, Bramhall JL, Fan TP, Bender A. Prediction and identification of synergistic compound combinations against pancreatic cancer cells. Iscience. 24: 103080. PMID 34585118 DOI: 10.1016/j.isci.2021.103080   
2021 Lu B, Liu D, Gui B, Gou J, Dong H, Hu Q, Feng J, Mao Y, Shen X, Wang S, Zhang C, Shen R, Yan Y, Chen L, Wang H, et al. Discovery of 2-(Ortho-Substituted Benzyl)-Indole Derivatives as Potent and Orally Bioavailable RORγ Agonists with Antitumor Activity. Journal of Medicinal Chemistry. PMID 34643383 DOI: 10.1021/acs.jmedchem.1c00828   
2021 Nelson GL, Ronayne CT, Solano LN, Jonnalagadda SK, Jonnalagadda S, Schumacher TJ, Gardner ZS, Palle H, Mani C, Rumbley J, Mereddy VR. Synthesis and biological evaluation of N, N-dialkylcarboxy coumarin-NO donor conjugates as potential anticancer agents. Bioorganic & Medicinal Chemistry Letters. 128411. PMID 34626786 DOI: 10.1016/j.bmcl.2021.128411   
2021 Goehringer N, Biersack B, Peng Y, Schobert R, Herling M, Ma A, Nitzsche B, Höpfner M. Anticancer Activity and Mechanisms of Action of New Chimeric EGFR/HDAC-Inhibitors. International Journal of Molecular Sciences. 22. PMID 34445133 DOI: 10.3390/ijms22168432   
2021 Cao Z, Yang F, Wang J, Gu Z, Lin S, Wang P, An J, Liu T, Li Y, Li Y, Lin H, Zhao Y, He B. Indirubin Derivatives as Dual Inhibitors Targeting Cyclin-Dependent Kinase and Histone Deacetylase for Treating Cancer. Journal of Medicinal Chemistry. PMID 34624191 DOI: 10.1021/acs.jmedchem.1c01311   
2021 Wang B, Feng W, Wang J, Dong Y, Liu Y, Yao Y, Zhang J, Shi W, Liu L, Zhang H, He X, Chang X, Wang X, Xu H, Liu F, et al. Discovery of potent and selective Bcl-2 inhibitors with acyl sulfonamide skeleton. Bioorganic & Medicinal Chemistry. 47: 116350. PMID 34536651 DOI: 10.1016/j.bmc.2021.116350   
2021 Yu KH, Hung CC, Wu TS, Chen CF, Wu IT, Kuo PC, Lam SH, Hung HY. Chemoreversal Agents from Taiwanofungus Genus and Their More Potent Methyl Derivatives Targeting Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation. Pharmaceuticals (Basel, Switzerland). 14. PMID 34577615 DOI: 10.3390/ph14090916   
2021 Sim S, Lee S, Ko S, Phuong Bui B, Linh Nguyen P, Cho J, Lee K, Kang JS, Jung JK, Lee H. Design, synthesis, and biological evaluation of potent 1,2,3,4-tetrahydroisoquinoline derivatives as anticancer agents targeting NF-κB signaling pathway. Bioorganic & Medicinal Chemistry. 46: 116371. PMID 34500188 DOI: 10.1016/j.bmc.2021.116371   
2021 Theofylaktou D, Takan I, Karakülah G, Biz GM, Zanni V, Pavlopoulou A, Georgakilas AG. Mining Natural Products with Anticancer Biological Activity through a Systems Biology Approach. Oxidative Medicine and Cellular Longevity. 2021: 9993518. PMID 34422220 DOI: 10.1155/2021/9993518   
2021 Jin S, Wang W, Gan F, Xie W, Xu J, Chen Y, Mei Z, Yang G. Discovery of Novel Polycyclic Polyprenylated Acylphloroglucinols from the Fruits of as Antitumor Agents by Suppressing the STAT3 Signaling. International Journal of Molecular Sciences. 22. PMID 34638708 DOI: 10.3390/ijms221910365   
2021 Gaber AA, El-Morsy AM, Sherbiny FF, Bayoumi AH, El-Gamal KM, El-Adl K, Al-Karmalawy AA, Ezz Eldin RR, Saleh MA, Abulkhair HS. Pharmacophore-linked pyrazolo[3,4-d]pyrimidines as EGFR-TK inhibitors: Synthesis, anticancer evaluation, pharmacokinetics, and in silico mechanistic studies. Archiv Der Pharmazie. e2100258. PMID 34467546 DOI: 10.1002/ardp.202100258   
2021 Mbaoji FN, Nweze JA, Yang L, Huang Y, Huang S, Onwuka AM, Peter IE, Mbaoji CC, Jiang M, Zhang Y, Pan L, Yang D. Novel Marine Secondary Metabolites Worthy of Development as Anticancer Agents: A Review. Molecules (Basel, Switzerland). 26. PMID 34641312 DOI: 10.3390/molecules26195769   
2021 Zhang H, Kong L, Zhang Y, Wang C, Sun L. Transcriptome and proteome analysis of the antitumor activity of maslinic acid against pancreatic cancer cells. Aging. 13. PMID 34637398 DOI: 10.18632/aging.203623   
2021 Poyya J, Kumar DJ, Nagendra HG, Dinesh B, Aditya Rao SJ, Joshi CG. Receptor based virtual screening of potential novel inhibitors of tigar [TP53 (tumour protein 53)-induced glycolysis and apoptosis regulator. Medical Hypotheses. 156: 110683. PMID 34583309 DOI: 10.1016/j.mehy.2021.110683   
2021 Neophytou CM, Trougakos IP, Erin N, Papageorgis P. Apoptosis Deregulation and the Development of Cancer Multi-Drug Resistance. Cancers. 13. PMID 34503172 DOI: 10.3390/cancers13174363   
2021 Wang S, Wang X, Shao Y, Shao K, Wang Y, Guo X, Dong H, Zhao W, Li Y, Li G. Synthesis and evaluation of 3-(phenylethynyl)-1,1'-biphenyl-2-carboxylate derivatives as new HIF-1 inhibitors. Bioorganic Chemistry. 116: 105298. PMID 34454298 DOI: 10.1016/j.bioorg.2021.105298   
2021 He M, Yin WQ, Sun HF, Ding YW, Xu S, Sun H, Wang JM, Yu P, Qin HJ, Chen MH. Four new fatty acid derivatives from sp. T24, an endophytic fungus isolated from . Journal of Asian Natural Products Research. 1-14. PMID 34622714 DOI: 10.1080/10286020.2021.1962309   
2021 Zheng Q, Xu XB, Jin H, Zhang W, Rao GW. Synthesis and anti-proliferation activity evaluation of novel 2-chloroquinazoline as potential EGFR-TK inhibitors. Chemistry & Biodiversity. PMID 34510749 DOI: 10.1002/cbdv.202100478   
2021 Dawood KM, Raslan MA, Abbas AA, Mohamed BE, Abdellattif MH, Nafie MS, Hassan MK. Novel -Thiazole Derivatives: Synthesis and Potential Cytotoxic Activity Through Apoptosis With Molecular Docking Approaches. Frontiers in Chemistry. 9: 694870. PMID 34458233 DOI: 10.3389/fchem.2021.694870   
2021 Xu T, Tian W, Zhang Q, Liu J, Liu Z, Jin J, Guo Y, Bai LP. Novel 1,3,4-thiadiazole/oxadiazole-linked honokiol derivatives suppress cancer via inducing PI3K/Akt/mTOR-dependent autophagy. Bioorganic Chemistry. 115: 105257. PMID 34426156 DOI: 10.1016/j.bioorg.2021.105257   
2021 Liu R, Huang M, Zhang S, Li L, Li M, Sun J, Wu L, Guan Q, Zhang W. Design, synthesis and bioevaluation of 6-aryl-1-(3,4,5-trimethoxyphenyl)-1H-benzo[d]imidazoles as tubulin polymerization inhibitors. European Journal of Medicinal Chemistry. 226: 113826. PMID 34571171 DOI: 10.1016/j.ejmech.2021.113826   
2021 Balbuena-Rebolledo I, Padilla-Martínez II, Rosales-Hernández MC, Bello M. Repurposing FDA Drug Compounds against Breast Cancer by Targeting EGFR/HER2. Pharmaceuticals (Basel, Switzerland). 14. PMID 34451888 DOI: 10.3390/ph14080791   
2021 Kumar S, Prajapati KS, Shuaib M, Kushwaha PP, Tuli HS, Singh AK. Five-Decade Update on Chemopreventive and Other Pharmacological Potential of Kurarinone: a Natural Flavanone. Frontiers in Pharmacology. 12: 737137. PMID 34646138 DOI: 10.3389/fphar.2021.737137   
2021 Kunwar S, Hwang SY, Katila P, Park S, Jeon KH, Kim D, Kadayat TM, Kwon Y, Lee ES. Discovery of a 2,4-diphenyl-5,6-dihydrobenzo(h)quinolin-8-amine derivative as a novel DNA intercalating topoisomerase IIα poison. European Journal of Medicinal Chemistry. 226: 113860. PMID 34597897 DOI: 10.1016/j.ejmech.2021.113860   
2021 Li H, Meng Y, Ma S, Dang C, Xue L. VALD-3 inhibits proliferation and induces apoptosis of colorectal cancer cells via upregulating tumor suppressor activity of p53 to inhibit Wnt/β-catenin signal pathway. Anti-Cancer Drugs. PMID 34419958 DOI: 10.1097/CAD.0000000000001116   
2021 Rodrigues DM, Portapilla GB, Silva GM, Duarte A, Rotta CG, da Silva CHTP, de Albuquerque S, Bastos JK, Campo VL. Synthesis, antitumor activity and in silico analyses of amino acid derivatives of artepillin C, drupanin and baccharin from green propolis. Bioorganic & Medicinal Chemistry. 47: 116372. PMID 34454129 DOI: 10.1016/j.bmc.2021.116372   
2021 Fetter BZ, Dourado DM, Bogo D, Matias R, Guterres ZR. Therapeutic potential of Smilax fluminensis ethanolic extract: antitumoral activity in murine melanoma cells. Molecular and Cellular Biochemistry. PMID 34637074 DOI: 10.1007/s11010-021-04272-5   
2021 Sharma B, Singh VJ, Chawla PA. Epidermal growth factor receptor inhibitors as potential anticancer agents: An update of recent progress. Bioorganic Chemistry. 116: 105393. PMID 34628226 DOI: 10.1016/j.bioorg.2021.105393   
2021 Wang Y, Li Y, Cao J, Meng Q, Li X, Zhang Y, Lam KS, Hong A, Liu R, Chen X. Development and Characterization of a Novel Peptide-Drug Conjugate with DM1 for Treatment of FGFR2-Positive Tumors. Biomedicines. 9. PMID 34440055 DOI: 10.3390/biomedicines9080849