Yong Xiong - Publications

Affiliations: 
Molecular Biophysics and Biochemistry Yale University, New Haven, CT 
Area:
Structural Biology, Mechanisms of Viral Pathogenesis
Website:
http://medicine.yale.edu/mbb/faculty/yong_xiong.profile

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Ziegler SJ, Liu C, Landau M, Buzovetsky O, Desimmie BA, Zhao Q, Sasaki T, Burdick RC, Pathak VK, Anderson KS, Xiong Y. Insights into DNA substrate selection by APOBEC3G from structural, biochemical, and functional studies. Plos One. 13: e0195048. PMID 29596531 DOI: 10.1371/journal.pone.0195048  0.56
2017 Nguyen HC, Wang W, Xiong Y. Cullin-RING E3 Ubiquitin Ligases: Bridges to Destruction. Sub-Cellular Biochemistry. 83: 323-347. PMID 28271482 DOI: 10.1007/978-3-319-46503-6_12  0.44
2016 Chen X, Yang K, Wu C, Chen C, Hu C, Buzovetsky O, Wang Z, Ji X, Xiong Y, Yang H. Mechanisms of activation and inhibition of Zika virus NS2B-NS3 protease. Cell Research. PMID 27752039 DOI: 10.1038/cr.2016.116  0.36
2016 Al-Yacoub N, Shaheen R, Awad SM, Kunhi M, Dzimiri N, Nguyen HC, Xiong Y, Al-Buraiki J, Al-Habeeb W, Alkuraya FS, Poizat C. FBXO32, encoding a member of the SCF complex, is mutated in dilated cardiomyopathy. Genome Biology. 17: 2. PMID 26753747 DOI: 10.1186/s13059-015-0861-4  0.64
2015 Tang C, Ji X, Wu L, Xiong Y. Impaired dNTPase Activity of SAMHD1 by Phosphomimetic Mutation of T592. The Journal of Biological Chemistry. PMID 26294762 DOI: 10.1074/jbc.M115.677435  0.64
2015 Jia X, Zhao Q, Xiong Y. HIV suppression by host restriction factors and viral immune evasion. Current Opinion in Structural Biology. 31: 106-14. PMID 25939065 DOI: 10.1016/j.sbi.2015.04.004  0.64
2015 Ji X, Xiong Y. Two tales (tails) of SAMHD1 destruction by Vpx. Cell Host & Microbe. 17: 425-7. PMID 25856752 DOI: 10.1016/j.chom.2015.03.013  0.64
2015 Nguyen HC, Yang H, Fribourgh JL, Wolfe LS, Xiong Y. Insights into Cullin-RING E3 ubiquitin ligase recruitment: structure of the VHL-EloBC-Cul2 complex. Structure (London, England : 1993). 23: 441-9. PMID 25661653 DOI: 10.1016/j.str.2014.12.014  0.64
2015 Alazami AM, Patel N, Shamseldin HE, Anazi S, Al-Dosari MS, Alzahrani F, Hijazi H, Alshammari M, Aldahmesh MA, Salih MA, Faqeih E, Alhashem A, Bashiri FA, Al-Owain M, Kentab AY, ... ... Xiong Y, et al. Accelerating novel candidate gene discovery in neurogenetic disorders via whole-exome sequencing of prescreened multiplex consanguineous families. Cell Reports. 10: 148-61. PMID 25558065 DOI: 10.1016/j.celrep.2014.12.015  0.44
2014 Zhao Q, Xue X, Longerich S, Sung P, Xiong Y. Structural insights into 5' flap DNA unwinding and incision by the human FAN1 dimer. Nature Communications. 5: 5726. PMID 25500724 DOI: 10.1038/ncomms6726  0.64
2014 Fribourgh JL, Nguyen HC, Matreyek KA, Alvarez FJD, Summers BJ, Dewdney TG, Aiken C, Zhang P, Engelman A, Xiong Y. Structural insight into HIV-1 restriction by MxB. Cell Host & Microbe. 16: 627-638. PMID 25312384 DOI: 10.1016/j.chom.2014.09.021  0.44
2014 Longerich S, Li J, Xiong Y, Sung P, Kupfer GM. Stress and DNA repair biology of the Fanconi anemia pathway. Blood. 124: 2812-9. PMID 25237197 DOI: 10.1182/blood-2014-04-526293  0.64
2014 Patel N, El Mouzan MI, Al-Mayouf SM, Adly N, Mohamed JY, Al Mofarreh MA, Ibrahim N, Xiong Y, Zhao Q, Al-Saleem KA, Alkuraya FS. Study of Mendelian forms of Crohn's disease in Saudi Arabia reveals novel risk loci and alleles. Gut. 63: 1831-2. PMID 25147203 DOI: 10.1136/gutjnl-2014-307859  0.64
2014 Uchil PD, Pawliczek T, Reynolds TD, Ding S, Hinz A, Munro JB, Huang F, Floyd RW, Yang H, Hamilton WL, Bewersdorf J, Xiong Y, Calderwood DA, Mothes W. TRIM15 is a focal adhesion protein that regulates focal adhesion disassembly. Journal of Cell Science. 127: 3928-42. PMID 25015296 DOI: 10.1242/jcs.143537  0.64
2014 Jia X, Weber E, Tokarev A, Lewinski M, Rizk M, Suarez M, Guatelli J, Xiong Y. Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1. Elife. 3: e02362. PMID 24843023 DOI: 10.7554/eLife.02362  0.64
2014 Shaheen R, Rahbeeni Z, Alhashem A, Faqeih E, Zhao Q, Xiong Y, Almoisheer A, Al-Qattan SM, Almadani HA, Al-Onazi N, Al-Baqawi BS, Saleh MA, Alkuraya FS. Neu-Laxova syndrome, an inborn error of serine metabolism, is caused by mutations in PHGDH. American Journal of Human Genetics. 94: 898-904. PMID 24836451 DOI: 10.1016/j.ajhg.2014.04.015  0.64
2014 Patel N, Khan AO, Mansour A, Mohamed JY, Al-Assiri A, Haddad R, Jia X, Xiong Y, Mégarbané A, Traboulsi EI, Alkuraya FS. Mutations in ASPH cause facial dysmorphism, lens dislocation, anterior-segment abnormalities, and spontaneous filtering blebs, or Traboulsi syndrome. American Journal of Human Genetics. 94: 755-9. PMID 24768550 DOI: 10.1016/j.ajhg.2014.04.002  0.64
2014 Aldahmesh MA, Li Y, Alhashem A, Anazi S, Alkuraya H, Hashem M, Awaji AA, Sogaty S, Alkharashi A, Alzahrani S, Al Hazzaa SA, Xiong Y, Kong S, Sun Z, Alkuraya FS. IFT27, encoding a small GTPase component of IFT particles, is mutated in a consanguineous family with Bardet-Biedl syndrome. Human Molecular Genetics. 23: 3307-15. PMID 24488770 DOI: 10.1093/hmg/ddu044  0.64
2014 Zhao Q, Saro D, Sachpatzidis A, Singh TR, Schlingman D, Zheng XF, Mack A, Tsai MS, Mochrie S, Regan L, Meetei AR, Sung P, Xiong Y. The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes. Nature Communications. 5: 2987. PMID 24390579 DOI: 10.1038/ncomms3987  0.64
2014 Fribourgh JL, Nguyen HC, Wolfe LS, Dewitt DC, Zhang W, Yu XF, Rhoades E, Xiong Y. Core binding factor beta plays a critical role by facilitating the assembly of the Vif-cullin 5 E3 ubiquitin ligase. Journal of Virology. 88: 3309-19. PMID 24390320 DOI: 10.1128/JVI.03824-13  0.64
2014 Liu C, Xiong Y. Electron density sharpening as a general technique in crystallographic studies. Journal of Molecular Biology. 426: 980-93. PMID 24269527 DOI: 10.1016/j.jmb.2013.11.014  0.64
2013 Ji X, Wu Y, Yan J, Mehrens J, Yang H, DeLucia M, Hao C, Gronenborn AM, Skowronski J, Ahn J, Xiong Y. Mechanism of allosteric activation of SAMHD1 by dGTP. Nature Structural & Molecular Biology. 20: 1304-9. PMID 24141705 DOI: 10.1038/nsmb.2692  0.64
2012 Yang H, Ji X, Zhao G, Ning J, Zhao Q, Aiken C, Gronenborn AM, Zhang P, Xiong Y. Structural insight into HIV-1 capsid recognition by rhesus TRIM5α Proceedings of the National Academy of Sciences of the United States of America. 109: 18372-18377. PMID 23091002 DOI: 10.1073/pnas.1210903109  0.64
2012 Zhen A, Du J, Zhou X, Xiong Y, Yu XF. Reduced APOBEC3H variant anti-viral activities are associated with altered RNA binding activities. Plos One. 7: e38771. PMID 22859935 DOI: 10.1371/journal.pone.0038771  0.64
2012 Jia X, Singh R, Homann S, Yang H, Guatelli J, Xiong Y. Structural basis of evasion of cellular adaptive immunity by HIV-1 Nef. Nature Structural & Molecular Biology. 19: 701-6. PMID 22705789 DOI: 10.1038/nsmb.2328  0.64
2012 Deng L, Gui X, Xiong Y, Gao S, Yang R, Rong Y, Hu J, Yan Y. End-stage liver disease: prevalence, risk factors and clinical characteristics in a cohort of HIV-HCV coinfected Han Chinese. Clinics and Research in Hepatology and Gastroenterology. 36: 574-82. PMID 22481087 DOI: 10.1016/j.clinre.2012.02.007  0.64
2012 Kim J, Roberts A, Yuan H, Xiong Y, Anderson KS. Nucleocapsid protein annealing of a primer-template enhances (+)-strand DNA synthesis and fidelity by HIV-1 reverse transcriptase. Journal of Molecular Biology. 415: 866-80. PMID 22210155 DOI: 10.1016/j.jmb.2011.12.034  0.64
2011 Burton JL, Xiong Y, Solomon MJ. Mechanisms of pseudosubstrate inhibition of the anaphase promoting complex by Acm1. The Embo Journal. 30: 1818-29. PMID 21460798 DOI: 10.1038/emboj.2011.90  0.64
2011 Butler EB, Xiong Y, Wang J, Strobel SA. Structural basis of cooperative ligand binding by the glycine riboswitch. Chemistry & Biology. 18: 293-8. PMID 21439473 DOI: 10.1016/j.chembiol.2011.01.013  0.64
2010 Pan B, Xiong Y, Steitz TA. How the CCA-adding enzyme selects adenine over cytosine at position 76 of tRNA. Science (New York, N.Y.). 330: 937-40. PMID 21071662 DOI: 10.1126/science.1194985  0.64
2010 Yang H, Wang J, Jia X, McNatt MW, Zang T, Pan B, Meng W, Wang HW, Bieniasz PD, Xiong Y. Structural insight into the mechanisms of enveloped virus tethering by tetherin. Proceedings of the National Academy of Sciences of the United States of America. 107: 18428-32. PMID 20940320 DOI: 10.1073/pnas.1011485107  0.64
2010 Wolfe LS, Calabrese MF, Nath A, Blaho DV, Miranker AD, Xiong Y. Protein-induced photophysical changes to the amyloid indicator dye thioflavin T. Proceedings of the National Academy of Sciences of the United States of America. 107: 16863-8. PMID 20826442 DOI: 10.1073/pnas.1002867107  0.64
2010 Yang RR, Gui X, Benoit JL, Xiong Y. The comparison of human immunodeficiency virus type 1 transmission between couples through blood or sex in central China. Japanese Journal of Infectious Diseases. 63: 283-5. PMID 20657071  0.64
2010 Wolfe LS, Stanley BJ, Liu C, Eliason WK, Xiong Y. Dissection of the HIV Vif interaction with human E3 ubiquitin ligase. Journal of Virology. 84: 7135-9. PMID 20463065 DOI: 10.1128/JVI.00031-10  0.64
2010 Singh TR, Saro D, Ali AM, Zheng XF, Du CH, Killen MW, Sachpatzidis A, Wahengbam K, Pierce AJ, Xiong Y, Sung P, Meetei AR. MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM. Molecular Cell. 37: 879-86. PMID 20347429 DOI: 10.1016/j.molcel.2010.01.036  0.64
2010 Murphy JW, Yuan H, Kong Y, Xiong Y, Lolis EJ. Heterologous quaternary structure of CXCL12 and its relationship to the CC chemokine family. Proteins. 78: 1331-7. PMID 20077567 DOI: 10.1002/prot.22666  0.64
2010 Zhen A, Wang T, Zhao K, Xiong Y, Yu XF. A single amino acid difference in human APOBEC3H variants determines HIV-1 Vif sensitivity. Journal of Virology. 84: 1902-11. PMID 19939923 DOI: 10.1128/JVI.01509-09  0.64
2009 Fang Y, Jayaram H, Shane T, Kolmakova-Partensky L, Wu F, Williams C, Xiong Y, Miller C. Structure of a prokaryotic virtual proton pump at 3.2 A resolution. Nature. 460: 1040-3. PMID 19578361 DOI: 10.1038/nature08201  0.64
2009 Randau L, Stanley BJ, Kohlway A, Mechta S, Xiong Y, Söll D. A cytidine deaminase edits C to U in transfer RNAs in Archaea. Science (New York, N.Y.). 324: 657-9. PMID 19407206 DOI: 10.1126/science.1170123  0.64
2008 Stanley BJ, Ehrlich ES, Short L, Yu Y, Xiao Z, Yu XF, Xiong Y. Structural insight into the human immunodeficiency virus Vif SOCS box and its role in human E3 ubiquitin ligase assembly. Journal of Virology. 82: 8656-63. PMID 18562529 DOI: 10.1128/JVI.00767-08  0.64
2008 Xiong Y. From electron microscopy to X-ray crystallography: molecular-replacement case studies. Acta Crystallographica. Section D, Biological Crystallography. 64: 76-82. PMID 18094470 DOI: 10.1107/S090744490705398X  0.64
2007 Xiao Z, Xiong Y, Zhang W, Tan L, Ehrlich E, Guo D, Yu XF. Characterization of a novel Cullin5 binding domain in HIV-1 Vif. Journal of Molecular Biology. 373: 541-50. PMID 17869271 DOI: 10.1016/j.jmb.2007.07.029  0.64
2007 Lomakin IB, Xiong Y, Steitz TA. The crystal structure of yeast fatty acid synthase, a cellular machine with eight active sites working together. Cell. 129: 319-32. PMID 17448991 DOI: 10.1016/j.cell.2007.03.013  0.64
2007 Xiao Z, Ehrlich E, Luo K, Xiong Y, Yu XF. Zinc chelation inhibits HIV Vif activity and liberates antiviral function of the cytidine deaminase APOBEC3G. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 217-22. PMID 17135358 DOI: 10.1096/fj.06-6773com  0.64
2006 Xiong Y, Steitz TA. A story with a good ending: tRNA 3'-end maturation by CCA-adding enzymes. Current Opinion in Structural Biology. 16: 12-7. PMID 16364630 DOI: 10.1016/j.sbi.2005.12.001  0.64
2005 Li W, Kamtekar S, Xiong Y, Sarkis GJ, Grindley ND, Steitz TA. Structure of a synaptic gammadelta resolvase tetramer covalently linked to two cleaved DNAs. Science (New York, N.Y.). 309: 1210-5. PMID 15994378 DOI: 10.1126/science.1112064  0.64
2005 Li Z, Xiong Y, Peng Y, Pan J, Chen Y, Wu X, Hussain S, Tien P, Guo D. Specific inhibition of HIV-1 replication by short hairpin RNAs targeting human cyclin T1 without inducing apoptosis. Febs Letters. 579: 3100-6. PMID 15913611 DOI: 10.1016/j.febslet.2005.04.074  0.64
2004 Xiong Y, Steitz TA. Mechanism of transfer RNA maturation by CCA-adding enzyme without using an oligonucleotide template. Nature. 430: 640-5. PMID 15295590 DOI: 10.1038/nature02711  0.64
2003 Xiong Y, Li F, Wang J, Weiner AM, Steitz TA. Crystal structures of an archaeal class I CCA-adding enzyme and its nucleotide complexes. Molecular Cell. 12: 1165-72. PMID 14636575 DOI: 10.1016/S1097-2765(03)00440-4  0.64
2003 Pan B, Xiong Y, Shi K, Sundaralingam M. Crystal structure of a bulged RNA tetraplex at 1.1 a resolution: implications for a novel binding site in RNA tetraplex. Structure (London, England : 1993). 11: 1423-30. PMID 14604532 DOI: 10.1016/j.str.2003.09.017  0.64
2003 Pan B, Xiong Y, Shi K, Sundaralingam M. An eight-stranded helical fragment in RNA crystal structure: implications for tetraplex interaction. Structure (London, England : 1993). 11: 825-31. PMID 12842045 DOI: 10.1016/S0969-2126(03)00108-4  0.64
2003 Pan B, Xiong Y, Shi K, Deng J, Sundaralingam M. Crystal structure of an RNA purine-rich tetraplex containing adenine tetrads: implications for specific binding in RNA tetraplexes. Structure (London, England : 1993). 11: 815-23. PMID 12842044 DOI: 10.1016/S0969-2126(03)00107-2  0.64
2003 Deng J, Xiong Y, Pan B, Sundaralingam M. Structure of an RNA dodecamer containing a fragment from SRP domain IV of Escherichia coli. Acta Crystallographica. Section D, Biological Crystallography. 59: 1004-11. PMID 12777762 DOI: 10.1107/S0907444903006747  0.64
2003 Main ER, Xiong Y, Cocco MJ, D'Andrea L, Regan L. Design of stable alpha-helical arrays from an idealized TPR motif. Structure (London, England : 1993). 11: 497-508. PMID 12737816 DOI: 10.1016/S0969-2126(03)00076-5  0.64
2002 Li F, Xiong Y, Wang J, Cho HD, Tomita K, Weiner AM, Steitz TA. Crystal structures of the Bacillus stearothermophilus CCA-adding enzyme and its complexes with ATP or CTP. Cell. 111: 815-24. PMID 12526808 DOI: 10.1016/S0092-8674(02)01115-7  0.64
2002 Mansy SS, Xiong Y, Hemann C, Hille R, Sundaralingam M, Cowan JA. Crystal structure and stability studies of C77S HiPIP: a serine ligated [4Fe-4S] cluster. Biochemistry. 41: 1195-201. PMID 11802718 DOI: 10.1021/bi011811y  0.64
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