Philipp Holliger - Publications

Affiliations: 
PNAC MRC Laboratory of Molecular Biology, Cambridge, England, United Kingdom 

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Wachowius F, Porebski BT, Johnson CM, Holliger P. Emergence of ATP- and GTP-Binding Aptamers from Single RNA Sequences by Error-Prone Replication and Selection. Chemsystemschem. 5. PMID 38074198 DOI: 10.1002/syst.202300006  0.531
2022 Hervey JRD, Freund N, Houlihan G, Dhaliwal G, Holliger P, Taylor AI. Efficient synthesis and replication of diverse sequence libraries composed of biostable nucleic acid analogues. Rsc Chemical Biology. 3: 1209-1215. PMID 36320888 DOI: 10.1039/d2cb00035k  0.496
2022 Freund N, Taylor AI, Arangundy-Franklin S, Subramanian N, Peak-Chew SY, Whitaker AM, Freudenthal BD, Abramov M, Herdewijn P, Holliger P. A two-residue nascent-strand steric gate controls synthesis of 2'-O-methyl- and 2'-O-(2-methoxyethyl)-RNA. Nature Chemistry. PMID 36229679 DOI: 10.1038/s41557-022-01050-8  0.635
2022 Taylor AI, Wan CJK, Donde MJ, Peak-Chew SY, Holliger P. A modular XNAzyme cleaves long, structured RNAs under physiological conditions and enables allele-specific gene silencing. Nature Chemistry. PMID 36064973 DOI: 10.1038/s41557-022-01021-z  0.531
2022 Li P, Holliger P, Tagami S. Hydrophobic-cationic peptides modulate RNA polymerase ribozyme activity by accretion. Nature Communications. 13: 3050. PMID 35665749 DOI: 10.1038/s41467-022-30590-3  0.532
2022 Kristoffersen EL, Burman M, Noy A, Holliger P. Rolling circle RNA synthesis catalyzed by RNA. Elife. 11. PMID 35108196 DOI: 10.7554/eLife.75186  0.659
2021 Freund N, Fürst MJLJ, Holliger P. New chemistries and enzymes for synthetic genetics. Current Opinion in Biotechnology. 74: 129-136. PMID 34883451 DOI: 10.1016/j.copbio.2021.11.004  0.377
2021 Christy TW, Giannetti CA, Houlihan G, Smola MJ, Rice GM, Wang J, Dokholyan NV, Laederach A, Holliger P, Weeks KM. Direct Mapping of Higher-Order RNA Interactions by SHAPE-JuMP. Biochemistry. PMID 34121404 DOI: 10.1021/acs.biochem.1c00270  0.7
2020 Houlihan G, Arangundy-Franklin S, Porebski BT, Subramanian N, Taylor AI, Holliger P. Discovery and evolution of RNA and XNA reverse transcriptase function and fidelity. Nature Chemistry. PMID 32690899 DOI: 10.1038/s41557-020-0502-8  0.628
2019 Wachowius F, Holliger P. Non-Enzymatic Assembly of a Minimized RNA Polymerase Ribozyme. Chemsystemschem. 1: 1-4. PMID 31673682 DOI: 10.1002/syst.201900004  0.63
2019 Rose KM, Alves Ferreira-Bravo I, Li M, Craigie R, Ditzler MA, Holliger P, DeStefano JJ. Selection of 2'-Deoxy-2'-Fluoroarabino Nucleic Acid (FANA) Aptamers that Bind HIV-1 Integrase with Picomolar Affinity. Acs Chemical Biology. PMID 31560515 DOI: 10.1021/Acschembio.9B00237  0.338
2019 Taylor AI, Houlihan G, Holliger P. Beyond DNA and RNA: The Expanding Toolbox of Synthetic Genetics. Cold Spring Harbor Perspectives in Biology. 11. PMID 31160351 DOI: 10.1101/cshperspect.a032490  0.514
2018 Mutschler H, Taylor AI, Porebski BT, Lightowlers A, Houlihan G, Abramov M, Herdewijn P, Holliger P. Random-sequence genetic oligomer pools display an innate potential for ligation and recombination. Elife. 7. PMID 30461419 DOI: 10.7554/Elife.43022  0.432
2018 Attwater J, Raguram A, Morgunov AS, Gianni E, Holliger P. Ribozyme-catalysed RNA synthesis using triplet building blocks. Elife. 7. PMID 29759114 DOI: 10.7554/eLife.35255  0.695
2017 Wachowius F, Attwater J, Holliger P. Nucleic acids: function and potential for abiogenesis. Quarterly Reviews of Biophysics. 50: e4. PMID 29233216 DOI: 10.1017/S0033583517000038  0.609
2017 Tagami S, Attwater J, Holliger P. Simple peptides derived from the ribosomal core potentiate RNA polymerase ribozyme function. Nature Chemistry. 9: 325-332. PMID 28338682 DOI: 10.1038/nchem.2739  0.584
2016 Taylor AI, Beuron F, Peak-Chew SY, Morris EP, Herdewijn P, Holliger P. Nanostructures from Synthetic Genetic Polymers. Chembiochem : a European Journal of Chemical Biology. PMID 26992063 DOI: 10.1002/Cbic.201600136  0.414
2015 Cozens C, Mutschler H, Nelson GM, Houlihan G, Taylor AI, Holliger P. Enzymatic Synthesis of Nucleic Acids with Defined Regioisomeric 2'-5' Linkages. Angewandte Chemie (International Ed. in English). PMID 26527364 DOI: 10.1002/anie.201508678  0.612
2015 Taylor AI, Holliger P. Directed evolution of artificial enzymes (XNAzymes) from diverse repertoires of synthetic genetic polymers. Nature Protocols. 10: 1625-42. PMID 26401917 DOI: 10.1038/nprot.2015.104  0.324
2015 Mutschler H, Wochner A, Holliger P. Freeze-thaw cycles as drivers of complex ribozyme assembly. Nature Chemistry. 7: 502-8. PMID 25991529 DOI: 10.1038/nchem.2251  0.633
2015 Taylor AI, Pinheiro VB, Smola MJ, Morgunov AS, Peak-Chew S, Cozens C, Weeks KM, Herdewijn P, Holliger P. Catalysts from synthetic genetic polymers. Nature. 518: 427-30. PMID 25470036 DOI: 10.1038/Nature13982  0.404
2014 Pinheiro VB, Arangundy-Franklin S, Holliger P. Compartmentalized Self-Tagging for In Vitro-Directed Evolution of XNA Polymerases. Current Protocols in Nucleic Acid Chemistry. 57: 9.9.1-18. PMID 24961724 DOI: 10.1002/0471142700.nc0909s57  0.323
2014 Pinheiro VB, Holliger P. Towards XNA nanotechnology: new materials from synthetic genetic polymers. Trends in Biotechnology. 32: 321-8. PMID 24745974 DOI: 10.1016/j.tibtech.2014.03.010  0.306
2014 Mutschler H, Holliger P. Non-canonical 3'-5' extension of RNA with prebiotically plausible ribonucleoside 2',3'-cyclic phosphates. Journal of the American Chemical Society. 136: 5193-6. PMID 24660752 DOI: 10.1021/ja4127714  0.597
2013 Attwater J, Wochner A, Holliger P. In-ice evolution of RNA polymerase ribozyme activity. Nature Chemistry. 5: 1011-8. PMID 24256864 DOI: 10.1038/nchem.1781  0.635
2013 Wynne SA, Pinheiro VB, Holliger P, Leslie AG. Structures of an apo and a binary complex of an evolved archeal B family DNA polymerase capable of synthesising highly cy-dye labelled DNA. Plos One. 8: e70892. PMID 23940661 DOI: 10.1371/journal.pone.0070892  0.318
2013 Pinheiro VB, Loakes D, Holliger P. Synthetic polymers and their potential as genetic materials. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 35: 113-22. PMID 23281109 DOI: 10.1002/bies.201200135  0.337
2012 Cozens C, Pinheiro VB, Vaisman A, Woodgate R, Holliger P. A short adaptive path from DNA to RNA polymerases. Proceedings of the National Academy of Sciences of the United States of America. 109: 8067-72. PMID 22566643 DOI: 10.1073/pnas.1120964109  0.51
2012 Pinheiro VB, Taylor AI, Cozens C, Abramov M, Renders M, Zhang S, Chaput JC, Wengel J, Peak-Chew SY, McLaughlin SH, Herdewijn P, Holliger P. Synthetic genetic polymers capable of heredity and evolution. Science (New York, N.Y.). 336: 341-4. PMID 22517858 DOI: 10.1126/Science.1217622  0.372
2010 Attwater J, Wochner A, Pinheiro VB, Coulson A, Holliger P. Ice as a protocellular medium for RNA replication. Nature Communications. 1: 76. PMID 20865803 DOI: 10.1038/ncomms1076  0.508
2009 Loakes D, Gallego J, Pinheiro VB, Kool ET, Holliger P. Evolving a polymerase for hydrophobic base analogues. Journal of the American Chemical Society. 131: 14827-37. PMID 19778048 DOI: 10.1021/Ja9039696  0.324
2007 Ghadessy FJ, Holliger P. Compartmentalized self-replication: a novel method for the directed evolution of polymerases and other enzymes. Methods in Molecular Biology (Clifton, N.J.). 352: 237-48. PMID 17041269 DOI: 10.1385/1-59745-187-8:237  0.305
2006 Ong JL, Loakes D, Jaroslawski S, Too K, Holliger P. Directed Evolution of DNA Polymerase, RNA Polymerase and Reverse Transcriptase Activity in a Single Polypeptide Journal of Molecular Biology. 361: 537-550. PMID 16859707 DOI: 10.1016/j.jmb.2006.06.050  0.513
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