Mamoun Alhamadsheh - Publications

2011 University of the Pacific, Stockton, CA, United States 
Chemistry, Biochemistry, Chemical Biology, Molecular Biology, Medicinal Chemistry, Pharmacokinetics

16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Penchala SC, Connelly S, Wang Y, Park MS, Zhao L, Baranczak A, Rappley I, Vogel H, Liedtke M, Witteles RM, Powers ET, Reixach N, Chan WK, Wilson IA, Kelly JW, ... ... Alhamadsheh MM, et al. AG10 inhibits amyloidogenesis and cellular toxicity of the familial amyloid cardiomyopathy-associated V122I transthyretin. Proceedings of the National Academy of Sciences of the United States of America. 110: 9992-7. PMID 23716704 DOI: 10.1073/pnas.1300761110  0.68
2011 Alhamadsheh MM, Connelly S, Cho A, Reixach N, Powers ET, Pan DW, Wilson IA, Kelly JW, Graef IA. Potent kinetic stabilizers that prevent transthyretin-mediated cardiomyocyte proteotoxicity. Science Translational Medicine. 3: 97ra81. PMID 21865539 DOI: 10.1126/scitranslmed.3002473  0.68
2011 Papireddy K, Smilkstein M, Kelly JX, Shweta, Salem SM, Alhamadsheh M, Haynes SW, Challis GL, Reynolds KA. Antimalarial activity of natural and synthetic prodiginines. Journal of Medicinal Chemistry. 54: 5296-306. PMID 21736388 DOI: 10.1021/jm200543y  0.68
2011 Whicher JR, Florova G, Sydor PK, Singh R, Alhamadsheh M, Challis GL, Reynolds KA, Smith JL. Structure and function of the RedJ protein, a thioesterase from the prodiginine biosynthetic pathway in Streptomyces coelicolor. The Journal of Biological Chemistry. 286: 22558-69. PMID 21543318 DOI: 10.1074/jbc.M110.213512  0.68
2009 Eustáquio AS, McGlinchey RP, Liu Y, Hazzard C, Beer LL, Florova G, Alhamadsheh MM, Lechner A, Kale AJ, Kobayashi Y, Reynolds KA, Moore BS. Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine. Proceedings of the National Academy of Sciences of the United States of America. 106: 12295-300. PMID 19590008 DOI: 10.1073/pnas.0901237106  0.68
2008 Alhamadsheh MM, Waters NC, Sachdeva S, Lee P, Reynolds KA. Synthesis and biological evaluation of novel sulfonyl-naphthalene-1,4-diols as FabH inhibitors. Bioorganic & Medicinal Chemistry Letters. 18: 6402-5. PMID 18996691 DOI: 10.1016/j.bmcl.2008.10.097  0.68
2008 Palaniappan N, Alhamadsheh MM, Reynolds KA. cis-Delta(2,3)-double bond of phoslactomycins is generated by a post-PKS tailoring enzyme. Journal of the American Chemical Society. 130: 12236-7. PMID 18714992 DOI: 10.1021/ja8044162  0.68
2008 Turos E, Revell KD, Ramaraju P, Gergeres DA, Greenhalgh K, Young A, Sathyanarayan N, Dickey S, Lim D, Alhamadsheh MM, Reynolds K. Unsymmetric aryl-alkyl disulfide growth inhibitors of methicillin-resistant Staphylococcus aureus and Bacillus anthracis. Bioorganic & Medicinal Chemistry. 16: 6501-8. PMID 18524602 DOI: 10.1016/j.bmc.2008.05.032  0.68
2008 Sachdeva S, Musayev FN, Alhamadsheh MM, Scarsdale JN, Wright HT, Reynolds KA. Separate entrance and exit portals for ligand traffic in Mycobacterium tuberculosis FabH. Chemistry & Biology. 15: 402-12. PMID 18420147 DOI: 10.1016/j.chembiol.2008.03.007  0.68
2008 Mo S, Sydor PK, Corre C, Alhamadsheh MM, Stanley AE, Haynes SW, Song L, Reynolds KA, Challis GL. Elucidation of the Streptomyces coelicolor pathway to 2-undecylpyrrole, a key intermediate in undecylprodiginine and streptorubin B biosynthesis. Chemistry & Biology. 15: 137-48. PMID 18291318 DOI: 10.1016/j.chembiol.2007.11.015  0.68
2008 Sachdeva S, Musayev F, Alhamadsheh MM, Neel Scarsdale J, Tonie Wright H, Reynolds KA. Probing reactivity and substrate specificity of both subunits of the dimeric Mycobacterium tuberculosis FabH using alkyl-CoA disulfide inhibitors and acyl-CoA substrates. Bioorganic Chemistry. 36: 85-90. PMID 18096200 DOI: 10.1016/j.bioorg.2007.11.001  0.68
2008 Alhamadsheh MM, Gupta S, Hudson RA, Perera L, Tillekeratne LM. Total synthesis and selective activity of a new class of conformationally restrained epothilones. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 570-81. PMID 17955508 DOI: 10.1002/chem.200701143  0.68
2007 Alhamadsheh MM, Musayev F, Komissarov AA, Sachdeva S, Wright HT, Scarsdale N, Florova G, Reynolds KA. Alkyl-CoA disulfides as inhibitors and mechanistic probes for FabH enzymes. Chemistry & Biology. 14: 513-24. PMID 17524982 DOI: 10.1016/j.chembiol.2007.03.013  0.68
2007 Alhamadsheh MM, Palaniappan N, Daschouduri S, Reynolds KA. Modular polyketide synthases and cis double bond formation: establishment of activated cis-3-cyclohexylpropenoic acid as the diketide intermediate in phoslactomycin biosynthesis. Journal of the American Chemical Society. 129: 1910-1. PMID 17256943 DOI: 10.1021/ja068818t  0.68
2007 Alhamadsheh MM, Waters NC, Huddler DP, Kreishman-Deitrick M, Florova G, Reynolds KA. Synthesis and biological evaluation of thiazolidine-2-one 1,1-dioxide as inhibitors of Escherichia coli beta-ketoacyl-ACP-synthase III (FabH). Bioorganic & Medicinal Chemistry Letters. 17: 879-83. PMID 17189694 DOI: 10.1016/j.bmcl.2006.11.067  0.68
2006 Alhamadsheh MM, Hudson RA, Viranga Tillekeratne LM. Design, total synthesis, and evaluation of novel open-chain epothilone analogues. Organic Letters. 8: 685-8. PMID 16468742 DOI: 10.1021/ol0528787  0.68
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