Wei Shi - Publications

Affiliations: 
University of Arkansas, Little Rock, AR 

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Li H, Wang Y, Lin K, Venkadakrishnan VB, Bakht M, Shi W, Meng C, Zhang J, Tremble K, Liang X, Song JH, Feng X, Van V, Deng P, Burks JK, et al. CHD1 promotes sensitivity to Aurora kinase inhibitors by suppressing interaction of AURKA with its coactivator TPX2. Cancer Research. PMID 35771632 DOI: 10.1158/0008-5472.CAN-22-0631  0.316
2022 Wang Q, Hu X, Shi W, Long H, Wang H. Design, synthesis and biological evaluation of chromone derivatives as novel protein kinase CK2 inhibitors. Bioorganic & Medicinal Chemistry Letters. 69: 128799. PMID 35580724 DOI: 10.1016/j.bmcl.2022.128799  0.364
2022 Shi W, Feng Z, Chi F, Zhou J, Qiu Q, Jiang Y, Chen S, Zhong Y, Jia H, Huang W, Qian H. Structure-based discovery of receptor tyrosine kinase AXL degraders with excellent anti-tumor activity by selectively degrading AXL and inducing methuosis. European Journal of Medicinal Chemistry. 234: 114253. PMID 35279611 DOI: 10.1016/j.ejmech.2022.114253  0.351
2021 Li Q, Feng H, Wang H, Wang Y, Mou W, Xu G, Zhang P, Li R, Shi W, Wang Z, Fang Z, Ren L, Wang Y, Lin L, Hou X, et al. Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7-NLRP3 interaction. Embo Reports. e53499. PMID 34882936 DOI: 10.15252/embr.202153499  0.341
2021 Shi W, Men L, Pi X, Jiang T, Peng D, Huo S, Luo P, Wang M, Guo J, Jiang Y, Peng L, Lin L, Li S, Lv J. Shikonin suppresses colon cancer cell growth and exerts synergistic effects by regulating ADAM17 and the IL‑6/STAT3 signaling pathway. International Journal of Oncology. 59. PMID 34726248 DOI: 10.3892/ijo.2021.5279  0.309
2021 Wei Z, Zhan X, Ding K, Xu G, Shi W, Ren L, Fang Z, Liu T, Hou X, Zhao J, Li H, Li J, Li Z, Li Q, Lin L, et al. Dihydrotanshinone I Specifically Inhibits NLRP3 Inflammasome Activation and Protects Against Septic Shock . Frontiers in Pharmacology. 12: 750815. PMID 34721038 DOI: 10.3389/fphar.2021.750815  0.352
2021 Wang B, Feng W, Wang J, Dong Y, Liu Y, Yao Y, Zhang J, Shi W, Liu L, Zhang H, He X, Chang X, Wang X, Xu H, Liu F, et al. Discovery of potent and selective Bcl-2 inhibitors with acyl sulfonamide skeleton. Bioorganic & Medicinal Chemistry. 47: 116350. PMID 34536651 DOI: 10.1016/j.bmc.2021.116350  0.382
2021 Shi W, Li J, Zhou J, Li Y, Lin H, Qian H, Fan W. Exploration of novel anti-angiogenic PEDF-derived peptides with improved activitives by inhibiting proliferation, suppressing migration, and inducing 67LR internalization. Bioorganic Chemistry. 116: 105323. PMID 34482170 DOI: 10.1016/j.bioorg.2021.105323  0.337
2021 Wang Y, Shi W, Wu C, Wan L, Zhao Y, Zhang C, Gu W, Wang S. Pyrazole ring-containing isolongifolanone derivatives as potential CDK2 inhibitors: Evaluation of anticancer activity and investigation of action mechanism. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 139: 111663. PMID 34243605 DOI: 10.1016/j.biopha.2021.111663  0.315
2021 Zhou C, Zhang Y, Chen J, Mei C, Xiong F, Shi W, Zhou W, Liu X, Sun S, Tian J, Ye Z, Wu Q, Qin X, Jiang J, Hou FF, et al. Association between serum advanced oxidation protein products and mortality risk in maintenance hemodialysis patients. Journal of Translational Medicine. 19: 284. PMID 34193178 DOI: 10.1186/s12967-021-02960-w  0.365
2021 Qin Q, Xu G, Zhan X, Wang Z, Wang Y, Liu H, Hou X, Shi W, Ma J, Bai Z, Xiao X. Brevilin A inhibits NLRP3 inflammasome activation in vivo and in vitro by acting on the upstream of NLRP3-induced ASC oligomerization. Molecular Immunology. 135: 116-126. PMID 33892379 DOI: 10.1016/j.molimm.2021.03.025  0.337
2021 Feng Z, Chen A, Shi J, Zhou D, Shi W, Qiu Q, Liu X, Huang W, Li J, Qian H, Zhang W. Design, synthesis, and biological activity evaluation of a series of novel sulfonamide derivatives as BRD4 inhibitors against acute myeloid leukemia. Bioorganic Chemistry. 111: 104849. PMID 33798846 DOI: 10.1016/j.bioorg.2021.104849  0.388
2021 Li J, Zhang W, Qiu Q, Zhou D, Feng Z, Tong Z, Wei J, Huang W, Li J, Qian H, Shi W. Design, synthesis and biological evaluation of novel 4,4-difluoro-1-methyl-N, 6-diphenyl-5, 6-dihydro-4H-pyrimido [4, 5-b] [1, 2, 4] triazolo [4, 3-d] [1, 4] diazepin-8-amine derivatives as potential BRD4 inhibitors. Chemical Biology & Drug Design. PMID 33638254 DOI: 10.1111/cbdd.13833  0.344
2021 Jiang J, Zhang Y, Chen J, Yang X, Mei C, Xiong F, Shi W, Zhou W, Liu X, Sun S, Zhang P, Zhang Y, Zhang Y, Liu S, Zhang Z, et al. Serum and Tissue Levels of Advanced Glycation End Products and Risk of Mortality in Patients on Maintenance Hemodialysis. American Journal of Nephrology. 1-9. PMID 33596571 DOI: 10.1159/000512385  0.359
2020 Liu H, Zhan X, Xu G, Wang Z, Li R, Wang Y, Qin Q, Shi W, Hou X, Yang R, Wang J, Xiaohe X, Bai Z. Cryptotanshinone specifically suppresses NLRP3 inflammasome activation and protects against inflammasome-mediated diseases. Pharmacological Research. 105384. PMID 33352229 DOI: 10.1016/j.phrs.2020.105384  0.307
2020 Xu G, Fu S, Zhan X, Wang Z, Zhang P, Shi W, Qin N, Chen Y, Wang C, Niu M, Guo Y, Wang JB, Bai Z, Xiao X. Echinatin effectively protects against NLRP3 inflammasome-driven diseases by targeting HSP90. Jci Insight. PMID 33350984 DOI: 10.1172/jci.insight.134601  0.327
2020 Zong G, Hu Z, Duah KB, Andrews LE, Zhou J, O'Keefe S, Whisenhunt L, Shim JS, Du Y, High S, Shi WQ. Ring Expansion Leads to a More Potent Analogue of Ipomoeassin F. The Journal of Organic Chemistry. PMID 33264019 DOI: 10.1021/acs.joc.0c01659  0.557
2020 Li Y, Pasunooti KK, Peng H, Li RJ, Shi WQ, Liu W, Cheng Z, Head SA, Liu JO. Design and Synthesis of Tetrazole- and Pyridine-Containing Itraconazole Analogs as Potent Angiogenesis Inhibitors. Acs Medicinal Chemistry Letters. 11: 1111-1117. PMID 32550989 DOI: 10.1021/Acsmedchemlett.9B00438  0.714
2020 Shi W, Xu G, Zhan X, Gao Y, Wang Z, Fu S, Qin N, Hou X, Ai Y, Wang C, He T, Liu H, Chen Y, Liu Y, Wang J, et al. Carnosol inhibits inflammasome activation by directly targeting HSP90 to treat inflammasome-mediated diseases. Cell Death & Disease. 11: 252. PMID 32312957 DOI: 10.1038/s41419-020-2460-x  0.36
2019 Ren J, Shi W, Zhao D, Wang Q, Chang X, He X, Wang X, Gao Y, Lu P, Zhang X, Xu H, Zhang Y. Design and synthesis of boron-containing diphenylpyrimidines as potent BTK and JAK3 dual inhibitors. Bioorganic & Medicinal Chemistry. 115236. PMID 31843459 DOI: 10.1016/j.bmc.2019.115236  0.323
2019 Bi X, Li J, Li J, Shi W, Dai Y, Li Q, Zhang W, Huang W, Qian H, Jiang C. Design, synthesis and biological evaluation of novel 4,5-dihydro-[1,2,4]triazolo[4,3-f]pteridine derivatives as potential BRD4 inhibitors. Bioorganic & Medicinal Chemistry. PMID 31079968 DOI: 10.1016/j.bmc.2019.05.006  0.375
2018 Kearney SE, Zahoránszky-Kőhalmi G, Brimacombe KR, Henderson MJ, Lynch C, Zhao T, Wan KK, Itkin Z, Dillon C, Shen M, Cheff DM, Lee TD, Bougie D, Cheng K, Coussens NP, ... ... Shi W, et al. Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space. Acs Central Science. 4: 1727-1741. PMID 30648156 DOI: 10.1021/Acscentsci.8B00747  0.349
2018 Zhang Y, Shi W. Steroid receptor coactivator-1 regulates glioma angiogenesis through polyomavirus enhancer activator 3 signaling. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. PMID 30532986 DOI: 10.1139/bcb-2018-0114  0.327
2018 Li Y, Pasunooti KK, Li RJ, Liu W, Head SA, Shi WQ, Liu JO. Novel Tetrazole-containing Analogs of Itraconazole as Potent Anti-angiogenic Agents with Reduced CYP3A4 Inhibition. Journal of Medicinal Chemistry. PMID 30481027 DOI: 10.1021/Acs.Jmedchem.8B01252  0.748
2018 Li N, Xu M, Bao N, Shi W, Li Q, Zhang X, Sun J, Chen L. Discovery of novel NO-releasing celastrol derivatives with Hsp90 inhibition and cytotoxic activities. European Journal of Medicinal Chemistry. 160: 1-8. PMID 30316059 DOI: 10.1016/j.ejmech.2018.10.013  0.31
2018 Bauer L, Ferla S, Head SA, Bhat S, Pasunooti KK, Shi WQ, Albulescu L, Liu JO, Brancale A, van Kuppeveld FJM, Strating JRPM. Structure-activity relationship study of itraconazole, a broad-range inhibitor of picornavirus replication that targets oxysterol-binding protein (OSBP). Antiviral Research. PMID 29807040 DOI: 10.1016/J.Antiviral.2018.05.010  0.794
2017 Cai D, Yao Y, Tang Y, Wang Z, Shi W, Huang W, Ding K. A Concise Synthesis of Three Branches Derived from Polysaccharide RN1 and Anti-Pancreatic Cancer Activity Study. Polymers. 9. PMID 30965840 DOI: 10.3390/polym9100536  0.322
2017 Gu W, Dai Y, Qiang H, Shi W, Liao C, Zhao F, Huang W, Qian H. Discovery of novel 2-substituted-4-(2-fluorophenoxy) pyridine derivatives possessing pyrazolone and triazole moieties as dual c-Met/VEGFR-2 receptor tyrosine kinase inhibitors. Bioorganic Chemistry. 72: 116-122. PMID 28411406 DOI: 10.1016/j.bioorg.2017.04.001  0.354
2017 Jiang W, Li X, Li T, Wang H, Shi W, Qi P, Li C, Chen J, Bao J, Huang G, Wang Y. Repositioning of amprenavir as a novel extracellular signal-regulated kinase-2 inhibitor and apoptosis inducer in MCF-7 human breast cancer. International Journal of Oncology. PMID 28197631 DOI: 10.3892/ijo.2017.3860  0.395
2017 Head SA, Shi WQ, Yang EJ, Nacev BA, Hong SY, Pasunooti KK, Li RJ, Shim JS, Liu JO. Simultaneous Targeting of NPC1 and VDAC1 by Itraconazole Leads to Synergistic Inhibition of mTOR Signaling and Angiogenesis. Acs Chemical Biology. 12: 174-182. PMID 28103683 DOI: 10.1021/Acschembio.6B00849  0.713
2017 Mu X, Zhao T, Xu C, Shi W, Geng B, Shen J, Zhang C, Pan J, Yang J, Hu S, Lv Y, Wen H, You Q. Oncometabolite succinate promotes angiogenesis by upregulating VEGF expression through GPR91-mediated STAT3 and ERK activation. Oncotarget. PMID 28061458 DOI: 10.18632/oncotarget.14485  0.336
2016 Zou P, Pei JH, Shi W, Chen L. [Anticancer drugs targeting glutathione S-transferase π]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica. 51: 241-7. PMID 29856577  0.339
2016 Shi W, Hu J, Bao N, Li D, Chen L, Sun J. Design, synthesis and cytotoxic activities of scopoletin-isoxazole and scopoletin-pyrazole hybrids. Bioorganic & Medicinal Chemistry Letters. PMID 27956344 DOI: 10.1016/j.bmcl.2016.11.089  0.314
2016 Wu Y, Pan M, Dai Y, Liu B, Cui J, Shi W, Qiu Q, Huang W, Qian H. Design, synthesis and biological evaluation of LBM-A5 derivatives as potent P-glycoprotein-mediated multidrug resistance inhibitors. Bioorganic & Medicinal Chemistry. PMID 27073052 DOI: 10.1016/j.bmc.2016.03.065  0.301
2016 Qiang H, Gu W, Huang D, Shi W, Qiu Q, Dai Y, Huang W, Qian H. Design, synthesis and biological evaluation of 4-aminopyrimidine-5-cabaldehyde oximes as dual inhibitors of c-Met and VEGFR-2. Bioorganic & Medicinal Chemistry. PMID 27068889 DOI: 10.1016/j.bmc.2016.03.061  0.328
2016 Shim JS, Li RJ, Bumpus N, Head S, Pasunooti K, Yang EJ, Lv J, Shi W, Liu JO. Divergence of Anti-angiogenic Activity and Hepatotoxicity of Different Stereoisomers of Itraconazole. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26801248 DOI: 10.1158/1078-0432.Ccr-15-1888  0.802
2015 Head SA, Shi W, Zhao L, Gorshkov K, Pasunooti K, Chen Y, Deng Z, Li RJ, Shim JS, Tan W, Hartung T, Zhang J, Zhao Y, Colombini M, Liu JO. Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 26655341 DOI: 10.1073/Pnas.1512867112  0.794
2015 Wang Y, Wang B, Guerram M, Sun L, Shi W, Tian C, Zhu X, Jiang Z, Zhang L. Deoxypodophyllotoxin suppresses tumor vasculature in HUVECs by promoting cytoskeleton remodeling through LKB1-AMPK dependent Rho A activatio. Oncotarget. 6: 29497-512. PMID 26470595 DOI: 10.18632/oncotarget.4985  0.346
2014 Yang S, Shi W, Xing D, Zhao Z, Lv F, Yang L, Yang Y, Hu W. Synthesis, antibacterial activity, and biological evaluation of formyl hydroxyamino derivatives as novel potent peptide deformylase inhibitors against drug-resistant bacteria. European Journal of Medicinal Chemistry. 86: 133-52. PMID 25151577 DOI: 10.1016/j.ejmech.2014.07.106  0.321
2014 Wang G, Jiang MY, Meng Y, Song HR, Shi W. Cellular mechanisms of a new pyrazinone compound that induces apoptosis in SKOV-3 cells. Asian Pacific Journal of Cancer Prevention : Apjcp. 15: 797-802. PMID 24568498 DOI: 10.7314/APJCP.2014.15.2.797  0.306
2012 Zhou QG, Jiang JP, Wu SJ, Tian JW, Chen JH, Yu XQ, Chen PY, Mei CL, Xiong F, Shi W, Zhou W, Liu XS, Sun SR, Xie D, Liu J, et al. Current pattern of Chinese dialysis units: a cohort study in a representative sample of units. Chinese Medical Journal. 125: 3434-9. PMID 23044302  0.411
2012 Zhang B, Shi W, Ma J, Sloan A, Faul C, Wei C, Reiser J, Yang Y, Liu S, Wang W. The calcineurin-NFAT pathway allows for urokinase receptor-mediated beta3 integrin signaling to cause podocyte injury. Journal of Molecular Medicine (Berlin, Germany). 90: 1407-20. PMID 23015147 DOI: 10.1007/S00109-012-0960-6  0.3
2012 Hou F, Jiang J, Chen J, Yu X, Zhou Q, Chen P, Mei C, Xiong F, Shi W, Zhou W, Liu X, Sun S, Xie D, Liu J, Zhang P, et al. China collaborative study on dialysis: a multi-centers cohort study on cardiovascular diseases in patients on maintenance dialysis. Bmc Nephrology. 13: 94. PMID 22935444 DOI: 10.1186/1471-2369-13-94  0.421
2012 Jiang J, Chen P, Chen J, Yu X, Xie D, Mei C, Xiong F, Shi W, Zhou W, Liu X, Sun S, Zhang P, Yang X, Zhang Y, Zhang Y, et al. Accumulation of tissue advanced glycation end products correlated with glucose exposure dose and associated with cardiovascular morbidity in patients on peritoneal dialysis. Atherosclerosis. 224: 187-94. PMID 22857897 DOI: 10.1016/j.atherosclerosis.2012.06.022  0.374
2012 Zhou Q, Wu S, Jiang J, Tian J, Chen J, Yu X, Chen P, Mei C, Xiong F, Shi W, Zhou W, Liu X, Sun S, Xie DI, Liu J, et al. Accumulation of circulating advanced oxidation protein products is an independent risk factor for ischaemic heart disease in maintenance haemodialysis patients. Nephrology (Carlton, Vic.). 17: 642-9. PMID 22738256 DOI: 10.1111/j.1440-1797.2012.01640.x  0.419
2012 Mu X, Shi W, Sun L, Li H, Jiang Z, Zhang L. Pristimerin, a triterpenoid, inhibits tumor angiogenesis by targeting VEGFR2 activation. Molecules (Basel, Switzerland). 17: 6854-68. PMID 22669041 DOI: 10.3390/molecules17066854  0.36
2012 Shi W, Han X, Yao J, Yang J, Shi Y. Combined effect of histone deacetylase inhibitor suberoylanilide hydroxamic acid and anti-CD20 monoclonal antibody rituximab on mantle cell lymphoma cells apoptosis. Leukemia Research. 36: 749-55. PMID 22475365 DOI: 10.1016/j.leukres.2012.01.027  0.304
2012 Peng CC, Shi W, Lutz JD, Kunze KL, Liu JO, Nelson WL, Isoherranen N. Stereospecific metabolism of itraconazole by CYP3A4: dioxolane ring scission of azole antifungals. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 426-35. PMID 22106171 DOI: 10.1124/Dmd.111.042739  0.439
2011 Shi W, Nacev BA, Aftab BT, Head S, Rudin CM, Liu JO. Itraconazole side chain analogues: structure-activity relationship studies for inhibition of endothelial cell proliferation, vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, and hedgehog signaling. Journal of Medicinal Chemistry. 54: 7363-74. PMID 21936514 DOI: 10.1021/Jm200944B  0.814
2011 Shi W, Lowary TL. Structure-activity relationships in glycosylated 2-phenyl-indoles, 2-phenyl-benzo[b]thiophenes and 2-phenyl-benzo[b]furans as DNA binding and potential antitumor agents. Bioorganic & Medicinal Chemistry. 19: 1779-89. PMID 21296580 DOI: 10.1016/J.Bmc.2011.01.014  0.353
2011 Shi W, Marcus SL, Lowary TL. Cytotoxicity and topoisomerase I/II inhibition of glycosylated 2-phenyl-indoles, 2-phenyl-benzo[b]thiophenes and 2-phenyl-benzo[b]furans. Bioorganic & Medicinal Chemistry. 19: 603-12. PMID 21094049 DOI: 10.1016/J.Bmc.2010.10.054  0.415
2010 Shi W, Nacev BA, Bhat S, Liu JO. Impact of Absolute Stereochemistry on the Antiangiogenic and Antifungal Activities of Itraconazole. Acs Medicinal Chemistry Letters. 1: 155-159. PMID 21892383 DOI: 10.1021/Ml1000068  0.791
2010 Shi W, Ma H, Duan Y, Aubart K, Fang Y, Zonis R, Yang L, Hu W. Design, synthesis and antibacterial activity of 3-methylenepyrrolidine formyl hydroxyamino derivatives as novel peptide deformylase inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 1060-3. PMID 21185180 DOI: 10.1016/j.bmcl.2010.11.102  0.333
2010 Shi W, Duan Y, Qian Y, Li M, Yang L, Hu W. Design, synthesis, and antibacterial activity of 2,5-dihydropyrrole formyl hydroxyamino derivatives as novel peptide deformylase inhibitors. Bioorganic & Medicinal Chemistry Letters. 20: 3592-5. PMID 20510610 DOI: 10.1016/j.bmcl.2010.04.123  0.341
2010 Liu H, Shi W, Luan F, Xu S, Yang F, Sun W, Liu J, Ma C. Hepatitis B virus X protein upregulates transcriptional activation of human telomerase reverse transcriptase. Virus Genes. 40: 174-82. PMID 20107884 DOI: 10.1007/s11262-009-0441-3  0.302
2010 Shi W, Marcus SL, Lowary TL. Synthesis and antibacterial activity of aminosugar-functionalized intercalating agents. Carbohydrate Research. 345: 10-22. PMID 19926076 DOI: 10.1016/J.Carres.2009.10.010  0.391
2009 Shi W, Coleman RS, Lowary TL. Synthesis and DNA-binding affinity studies of glycosylated intercalators designed as functional mimics of the anthracycline antibiotics. Organic & Biomolecular Chemistry. 7: 3709-22. PMID 19707675 DOI: 10.1039/B909153J  0.321
2007 Fan E, Shi W, Lowary TL. Synthesis of daunorubicin analogues containing truncated aromatic cores and unnatural monosaccharide residues. The Journal of Organic Chemistry. 72: 2917-28. PMID 17373847 DOI: 10.1021/Jo062542Q  0.414
2001 Shi W, Qian X, Zhang R, Song G. Synthesis and Quantitative Structure−Activity Relationships of New 2,5-Disubstituted-1,3,4-oxadiazoles Journal of Agricultural and Food Chemistry. 49: 124-130. PMID 11170568 DOI: 10.1021/Jf0007941  0.317
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