James P. Snyder - Publications

Chemistry Emory University, Atlanta, GA 

176 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Katzman BM, Cox BD, Prosser AR, Alcaraz AA, Murat B, Héroux M, Tebben A, Zhang Y, Schroeder GM, Snyder JP, Wilson LJ, Liotta DC. Tetrahydroisoquinoline CXCR4 Antagonists Adopt a Hybrid Binding Mode within the Peptide Subpocket of the CXCR4 Receptor. Acs Medicinal Chemistry Letters. 10: 67-73. PMID 30655949 DOI: 10.1021/Acsmedchemlett.8B00441  0.44
2018 Wells G, Yuan H, McDaniel MJ, Kusumoto H, Snyder JP, Liotta DC, Traynelis SF. The GluN2B-Glu413Gly NMDA receptor variant arising from a de novo GRIN2B mutation promotes ligand-unbinding and domain opening. Proteins. PMID 30168177 DOI: 10.1002/Prot.25595  0.44
2016 Rajitha B, Nagaraju GP, Shaib WL, Alese OB, Snyder JP, Shoji M, Pattnaik S, Alam A, El-Rayes BF. Novel synthetic curcumin analogs as potent antiangiogenic agents in colorectal cancer. Molecular Carcinogenesis. PMID 27128654 DOI: 10.1002/Mc.22492  0.44
2016 Rajitha B, Belalcazar A, Nagaraju GP, Shaib WL, Snyder JP, Shoji M, Pattnaik S, Alam A, El-Rayes BF. Inhibition of NF-κB translocation by curcumin analogs induces G0/G1 arrest and downregulates thymidylate synthase in colorectal cancer. Cancer Letters. PMID 26850372 DOI: 10.1016/J.Canlet.2016.01.052  0.32
2015 Wang SR, Yang CG, Sánchez-Murcia PA, Snyder JP, Yan N, Sáez-Calvo G, Díaz JF, Gago F, Fang WS. Restoration of Microtubule Interaction and Cytotoxicity in D-seco Taxanes upon Incorporation of 20-Hydroxymethyl-4-allyloxy Groups. Organic Letters. PMID 26649936 DOI: 10.1021/Acs.Orglett.5B03119  0.44
2015 Cox BD, Mehta AK, DiRaddo JO, Liotta DC, Wilson LJ, Snyder JP. Structural analysis of CXCR4 - Antagonist interactions using saturation-transfer double-difference NMR. Biochemical and Biophysical Research Communications. 466: 28-32. PMID 26301631 DOI: 10.1016/J.Bbrc.2015.08.084  0.44
2015 Curry E, Green I, Chapman-Rothe N, Shamsaei E, Kandil S, Cherblanc FL, Payne L, Bell E, Ganesh T, Srimongkolpithak N, Caron J, Li F, Uren AG, Snyder JP, Vedadi M, et al. Dual EZH2 and EHMT2 histone methyltransferase inhibition increases biological efficacy in breast cancer cells. Clinical Epigenetics. 7: 84. PMID 26300989 DOI: 10.1016/S0959-8049(14)70680-X  0.44
2015 Cox BD, Prosser AR, Sun Y, Li Z, Lee S, Huang MB, Bond VC, Snyder JP, Krystal M, Wilson LJ, Liotta DC. Pyrazolo-Piperidines Exhibit Dual Inhibition of CCR5/CXCR4 HIV Entry and Reverse Transcriptase. Acs Medicinal Chemistry Letters. 6: 753-7. PMID 26191361 DOI: 10.1021/Acsmedchemlett.5B00036  0.44
2015 Shi Q, Kaiser TM, Dentmon ZW, Ceruso M, Vullo D, Supuran CT, Snyder JP. Design and Validation of FRESH, a Drug Discovery Paradigm Resting on Robust Chemical Synthesis. Acs Medicinal Chemistry Letters. 6: 518-22. PMID 26005525 DOI: 10.1021/Acsmedchemlett.5B00062  0.44
2015 Yuan H, Myers SJ, Wells G, Nicholson KL, Swanger SA, Lyuboslavsky P, Tahirovic YA, Menaldino DS, Ganesh T, Wilson LJ, Liotta DC, Snyder JP, Traynelis SF. Context-dependent GluN2B-selective inhibitors of NMDA receptor function are neuroprotective with minimal side effects. Neuron. 85: 1305-18. PMID 25728572 DOI: 10.1016/J.Neuron.2015.02.008  0.44
2015 Baldwin PR, Reeves AZ, Powell KR, Napier RJ, Swimm AI, Sun A, Giesler K, Bommarius B, Shinnick TM, Snyder JP, Liotta DC, Kalman D. Monocarbonyl analogs of curcumin inhibit growth of antibiotic sensitive and resistant strains of Mycobacterium tuberculosis. European Journal of Medicinal Chemistry. 92: 693-9. PMID 25618016 DOI: 10.1016/J.Ejmech.2015.01.020  0.44
2015 Shetty D, Kim YJ, Shim H, Snyder JP. Eliminating the heart from the curcumin molecule: monocarbonyl curcumin mimics (MACs). Molecules (Basel, Switzerland). 20: 249-92. PMID 25547726 DOI: 10.3390/Molecules20010249  0.2
2015 Basciano PA, Matakas J, Pecci A, Civaschi E, Cagioni C, Bompiani N, Burger P, Christos P, Snyder JP, Bussel J, Balduini CL, Giannakakou P, Noris P. β-1 tubulin R307H SNP alters microtubule dynamics and affects severity of a hereditary thrombocytopenia. Journal of Thrombosis and Haemostasis : Jth. 13: 651-9. PMID 25529050 DOI: 10.1111/Jth.12824  0.08
2015 Zhu S, Kisiel W, Lu YJ, Petersen LC, Ndungu JM, Moore TW, Parker ET, Sun A, Sarkaria JN, Snyder JP, Liotta DC, Brat DJ, El-Rayes BF, Shoji M. Visualizing cancer and response to therapy in vivo using Cy5.5-labeled factor VIIa and anti-tissue factor antibody. Journal of Drug Targeting. 23: 257-65. PMID 25510254 DOI: 10.3109/1061186X.2014.988217  0.44
2015 Nagaraju GP, Zhu S, Ko JE, Ashritha N, Kandimalla R, Snyder JP, Shoji M, El-Rayes BF. Antiangiogenic effects of a novel synthetic curcumin analogue in pancreatic cancer. Cancer Letters. 357: 557-65. PMID 25497868 DOI: 10.1016/J.Canlet.2014.12.007  0.32
2015 Yamaguchi M, Zhu S, Weitzmann MN, Snyder JP, Shoji M. Curcumin analog UBS109 prevents bone marrow osteoblastogenesis and osteoclastogenesis disordered by coculture with breast cancer MDA-MB-231 bone metastatic cells in vitro. Molecular and Cellular Biochemistry. 401: 1-10. PMID 25416449 DOI: 10.1007/S11010-014-2286-X  0.32
2014 Zhu S, Kisiel W, Lu YJ, Petersen LC, Ndungu JM, Moore TW, Parker ET, Sun A, Liotta DC, El-Rayes BF, Brat DJ, Snyder JP, Shoji M. Tumor angiogenesis therapy using targeted delivery of Paclitaxel to the vasculature of breast cancer metastases. Journal of Drug Delivery. 2014: 865732. PMID 25574399 DOI: 10.1155/2014/865732  0.44
2014 Kim MS, Buisson LA, Heathcote DA, Hu H, Braddock DC, Barrett AG, Ashton-Rickardt PG, Snyder JP. Approaches to design non-covalent inhibitors for human granzyme B (hGrB). Organic & Biomolecular Chemistry. 12: 8952-65. PMID 25277547 DOI: 10.1039/C4Ob01874E  0.16
2014 Zhou T, Ye L, Bai Y, Sun A, Cox B, Liu D, Li Y, Liotta D, Snyder JP, Fu H, Huang B. Autophagy and apoptosis in hepatocellular carcinoma induced by EF25-(GSH)2: a novel curcumin analog. Plos One. 9: e107876. PMID 25268357 DOI: 10.1371/Journal.Pone.0107876  0.44
2014 Khatri A, Burger PB, Swanger SA, Hansen KB, Zimmerman S, Karakas E, Liotta DC, Furukawa H, Snyder JP, Traynelis SF. Structural determinants and mechanism of action of a GluN2C-selective NMDA receptor positive allosteric modulator. Molecular Pharmacology. 86: 548-60. PMID 25205677 DOI: 10.1124/Mol.114.094516  0.44
2014 Grimmer C, Moore TW, Padwa A, Prussia A, Wells G, Wu S, Sun A, Snyder JP. Antiviral atropisomers: conformational energy surfaces by NMR for host-directed myxovirus blockers. Journal of Chemical Information and Modeling. 54: 2214-23. PMID 25058809 DOI: 10.1021/Ci500204J  0.44
2014 Kingston DG, Snyder JP. The quest for a simple bioactive analog of paclitaxel as a potential anticancer agent. Accounts of Chemical Research. 47: 2682-91. PMID 25052294 DOI: 10.1021/Ar500203H  0.04
2014 Cox BD, Prosser AR, Katzman BM, Alcaraz AA, Liotta DC, Wilson LJ, Snyder JP. Anti-HIV small-molecule binding in the peptide subpocket of the CXCR4:CVX15 crystal structure. Chembiochem : a European Journal of Chemical Biology. 15: 1614-20. PMID 24990206 DOI: 10.1002/Cbic.201402056  0.44
2014 Moore TW, Zhu S, Randolph R, Shoji M, Snyder JP. Liver S9 Fraction-Derived Metabolites of Curcumin Analogue UBS109. Acs Medicinal Chemistry Letters. 5: 288-92. PMID 24900828 DOI: 10.1021/Ml4002453  0.32
2014 Hu H, Mao S, Bugrysheva JV, Pruett S, Liotta DC, Scott JR, Snyder JP. Group A streptococcus inhibitors by high-throughput virtual screening. European Journal of Medicinal Chemistry. 82: 120-6. PMID 24880231 DOI: 10.1016/J.Ejmech.2014.05.006  0.44
2014 Adams DR, Yuan H, Holyoak T, Arajs KH, Hakimi P, Markello TC, Wolfe LA, Vilboux T, Burton BK, Fajardo KF, Grahame G, Holloman C, Sincan M, Smith AC, Wells GA, ... Snyder JP, et al. Three rare diseases in one Sib pair: RAI1, PCK1, GRIN2B mutations associated with Smith-Magenis Syndrome, cytosolic PEPCK deficiency and NMDA receptor glutamate insensitivity. Molecular Genetics and Metabolism. 113: 161-70. PMID 24863970 DOI: 10.1016/J.Ymgme.2014.04.001  0.44
2014 Reid JM, Buhrow SA, Gilbert JA, Jia L, Shoji M, Snyder JP, Ames MM. Mouse pharmacokinetics and metabolism of the curcumin analog, 4-piperidinone,3,5-bis[(2-fluorophenyl)methylene]-acetate(3E,5E) (EF-24; NSC 716993). Cancer Chemotherapy and Pharmacology. 73: 1137-46. PMID 24760417 DOI: 10.1007/S00280-014-2447-3  0.44
2014 Yamaguchi M, Zhu S, Zhang S, Wu D, Moore TM, Snyder JP, Shoji M. Curcumin analogue UBS109 prevents bone loss in breast cancer bone metastasis mouse model: involvement in osteoblastogenesis and osteoclastogenesis. Cell and Tissue Research. 357: 245-52. PMID 24723227 DOI: 10.1007/S00441-014-1846-4  0.44
2014 Zhu S, Moore TW, Morii N, Howard RB, Culver D, Arrendale RF, Reddy P, Evers TJ, Zhang H, Sica G, Chen ZG, Sun A, Fu H, Khuri FR, Shin DM, Snyder JP, et al. Synthetic curcumin analog UBS109 inhibits the growth of head and neck squamous cell carcinoma xenografts. Current Cancer Drug Targets. 14: 380-93. PMID 24628271 DOI: 10.2174/1568009614666140312163524  0.36
2014 Jenkins MA, Wells G, Bachman J, Snyder JP, Jenkins A, Huganir RL, Oswald RE, Traynelis SF. Regulation of GluA1 α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor function by protein kinase C at serine-818 and threonine-840. Molecular Pharmacology. 85: 618-29. PMID 24452473 DOI: 10.1124/Mol.113.091488  0.44
2013 Truax VM, Zhao H, Katzman BM, Prosser AR, Alcaraz AA, Saindane MT, Howard RB, Culver D, Arrendale RF, Gruddanti PR, Evers TJ, Natchus MG, Snyder JP, Liotta DC, Wilson LJ. Discovery of tetrahydroisoquinoline-based CXCR4 antagonists. Acs Medicinal Chemistry Letters. 4: 1025-30. PMID 24936240 DOI: 10.1021/Ml400183Q  0.44
2013 Moore TW, Sana K, Yan D, Krumm SA, Thepchatri P, Snyder JP, Marengo J, Arrendale RF, Prussia AJ, Natchus MG, Liotta DC, Plemper RK, Sun A. Synthesis and Metabolic Studies of Host Directed Inhibitors for Anti Viral Therapy. Acs Medicinal Chemistry Letters. 4: 762-767. PMID 23956816 DOI: 10.1021/Ml400166B  0.44
2013 Nagaraju GP, Zhu S, Wen J, Farris AB, Adsay VN, Diaz R, Snyder JP, Mamoru S, El-Rayes BF. Novel synthetic curcumin analogues EF31 and UBS109 are potent DNA hypomethylating agents in pancreatic cancer. Cancer Letters. 341: 195-203. PMID 23933177 DOI: 10.1016/J.Canlet.2013.08.002  0.16
2013 Acker TM, Khatri A, Vance KM, Slabber C, Bacsa J, Snyder JP, Traynelis SF, Liotta DC. Structure-activity relationships and pharmacophore model of a noncompetitive pyrazoline containing class of GluN2C/GluN2D selective antagonists. Journal of Medicinal Chemistry. 56: 6434-56. PMID 23909910 DOI: 10.1021/Jm400652R  0.44
2013 Brown A, Shi Q, Moore TW, Yoon Y, Prussia A, Maddox C, Liotta DC, Shim H, Snyder JP. Monocarbonyl curcumin analogues: heterocyclic pleiotropic kinase inhibitors that mediate anticancer properties. Journal of Medicinal Chemistry. 56: 3456-66. PMID 23550937 DOI: 10.1021/Jm4002692  0.44
2013 Mooring SR, Liu J, Liang Z, Ahn J, Hong S, Yoon Y, Snyder JP, Shim H. Benzenesulfonamides: a unique class of chemokine receptor type 4 inhibitors. Chemmedchem. 8: 622-32. PMID 23468189 DOI: 10.1002/Cmdc.201200582  0.44
2013 Moore TW, Sana K, Yan D, Thepchatri P, Ndungu JM, Saindane MT, Lockwood MA, Natchus MG, Liotta DC, Plemper RK, Snyder JP, Sun A. Asymmetric synthesis of host-directed inhibitors of myxoviruses. Beilstein Journal of Organic Chemistry. 9: 197-203. PMID 23400228 DOI: 10.3762/Bjoc.9.23  0.44
2012 Shi Q, Yin S, Kaluz S, Ni N, Devi NS, Mun J, Wang D, Damera K, Chen W, Burroughs S, Mooring SR, Goodman MM, Van Meir EG, Wang B, Snyder JP. Binding Model for the Interaction of Anticancer Arylsulfonamides with the p300 Transcription Cofactor. Acs Medicinal Chemistry Letters. 3: 620-5. PMID 24936238 DOI: 10.1021/Ml300042K  0.44
2012 Hu H, Snyder JP. Models for predicting IKKA and IKKB blockade. Journal of Chemical Information and Modeling. 52: 3190-9. PMID 23157456 DOI: 10.1021/Ci300287T  0.16
2012 Rey J, Hu H, Kyle F, Lai CF, Buluwela L, Coombes RC, Ortlund EA, Ali S, Snyder JP, Barrett AG. Discovery of a new class of liver receptor homolog-1 (LRH-1) antagonists: virtual screening, synthesis and biological evaluation. Chemmedchem. 7: 1909-14. PMID 22961990 DOI: 10.1002/Cmdc.201200307  0.44
2012 Yamaguchi M, Moore TW, Sun A, Snyder JP, Shoji M. Novel curcumin analogue UBS109 potently stimulates osteoblastogenesis and suppresses osteoclastogenesis: involvement in Smad activation and NF-κB inhibition. Integrative Biology : Quantitative Biosciences From Nano to Macro. 4: 905-13. PMID 22751853 DOI: 10.1039/C2Ib20045G  0.32
2012 Mun J, Jabbar AA, Devi NS, Yin S, Wang Y, Tan C, Culver D, Snyder JP, Van Meir EG, Goodman MM. Design and in vitro activities of N-alkyl-N-[(8-R-2,2-dimethyl-2H-chromen-6-yl)methyl]heteroarylsulfonamides, novel, small-molecule hypoxia inducible factor-1 pathway inhibitors and anticancer agents. Journal of Medicinal Chemistry. 55: 6738-50. PMID 22746274 DOI: 10.1021/Jm300752N  0.44
2012 Smith SM, Min J, Ganesh T, Diebold B, Kawahara T, Zhu Y, McCoy J, Sun A, Snyder JP, Fu H, Du Y, Lewis I, Lambeth JD. Ebselen and congeners inhibit NADPH oxidase 2-dependent superoxide generation by interrupting the binding of regulatory subunits. Chemistry & Biology. 19: 752-63. PMID 22726689 DOI: 10.1016/J.Chembiol.2012.04.015  0.32
2012 Burger PB, Yuan H, Karakas E, Geballe M, Furukawa H, Liotta DC, Snyder JP, Traynelis SF. Mapping the binding of GluN2B-selective N-methyl-D-aspartate receptor negative allosteric modulators. Molecular Pharmacology. 82: 344-59. PMID 22596351 DOI: 10.1124/Mol.112.078568  0.44
2012 Zhu S, Moore TW, Lin X, Morii N, Mancini A, Howard RB, Culver D, Arrendale RF, Reddy P, Evers TJ, Zhang H, Sica G, Chen ZG, Sun A, Fu H, ... Snyder JP, et al. Synthetic curcumin analog EF31 inhibits the growth of head and neck squamous cell carcinoma xenografts. Integrative Biology : Quantitative Biosciences From Nano to Macro. 4: 633-40. PMID 22532032 DOI: 10.1039/C2Ib20007D  0.36
2012 Liang Z, Zhan W, Zhu A, Yoon Y, Lin S, Sasaki M, Klapproth JM, Yang H, Grossniklaus HE, Xu J, Rojas M, Voll RJ, Goodman MM, Arrendale RF, Liu J, ... Snyder JP, et al. Development of a unique small molecule modulator of CXCR4. Plos One. 7: e34038. PMID 22485156 DOI: 10.1371/Journal.Pone.0034038  0.44
2012 Ndungu JM, Krumm SA, Yan D, Arrendale RF, Reddy GP, Evers T, Howard R, Natchus MG, Saindane MT, Liotta DC, Plemper RK, Snyder JP, Sun A. Non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase: synthesis, structure-activity relationships, and pharmacokinetics. Journal of Medicinal Chemistry. 55: 4220-30. PMID 22480182 DOI: 10.1021/Jm201699W  0.44
2012 Olivera A, Moore TW, Hu F, Brown AP, Sun A, Liotta DC, Snyder JP, Yoon Y, Shim H, Marcus AI, Miller AH, Pace TW. Inhibition of the NF-κB signaling pathway by the curcumin analog, 3,5-Bis(2-pyridinylmethylidene)-4-piperidone (EF31): anti-inflammatory and anti-cancer properties. International Immunopharmacology. 12: 368-77. PMID 22197802 DOI: 10.1016/J.Intimp.2011.12.009  0.44
2011 Sun A, Ndungu JM, Krumm SA, Yoon JJ, Thepchatri P, Natchus M, Plemper RK, Snyder JP. Host-directed Inhibitors of Myxoviruses: Synthesis and in vitro Biochemical Evaluation. Acs Medicinal Chemistry Letters. 2: 798-803. PMID 22328961 DOI: 10.1021/Ml200125R  0.32
2011 Zhan W, Jiang Y, Sharma S, Brodie PJ, Bane S, Kingston DG, Liotta DC, Snyder JP. C6-C8 bridged epothilones: consequences of installing a conformational lock at the edge of the macrocycle. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 14792-804. PMID 22127984 DOI: 10.1002/Chem.201102630  0.44
2011 Zhao J, Bane S, Snyder JP, Hu H, Mukherjee K, Slebodnick C, Kingston DG. Design and synthesis of simplified taxol analogs based on the T-Taxol bioactive conformation. Bioorganic & Medicinal Chemistry. 19: 7664-78. PMID 22071526 DOI: 10.1016/J.Bmc.2011.10.010  0.24
2011 Acker TM, Yuan H, Hansen KB, Vance KM, Ogden KK, Jensen HS, Burger PB, Mullasseril P, Snyder JP, Liotta DC, Traynelis SF. Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-D-aspartate receptor subunit-selective modulators. Molecular Pharmacology. 80: 782-95. PMID 21807990 DOI: 10.1124/Mol.111.073239  0.44
2011 Prussia A, Thepchatri P, Snyder JP, Plemper RK. Systematic approaches towards the development of host-directed antiviral therapeutics. International Journal of Molecular Sciences. 12: 4027-52. PMID 21747723 DOI: 10.3390/Ijms12064027  0.16
2011 Krumm SA, Ndungu JM, Yoon JJ, Dochow M, Sun A, Natchus M, Snyder JP, Plemper RK. Potent host-directed small-molecule inhibitors of myxovirus RNA-dependent RNA-polymerases. Plos One. 6: e20069. PMID 21603574 DOI: 10.1371/Journal.Pone.0020069  0.32
2011 Sun A, Moore TW, Gunther JR, Kim MS, Rhoden E, Du Y, Fu H, Snyder JP, Katzenellenbogen JA. Discovering small-molecule estrogen receptor α/coactivator binding inhibitors: high-throughput screening, ligand development, and models for enhanced potency. Chemmedchem. 6: 654-66. PMID 21365764 DOI: 10.1002/Cmdc.201000507  0.44
2011 Jogalekar AS, Damodaran K, Kriel FH, Jung WH, Alcaraz AA, Zhong S, Curran DP, Snyder JP. Dictyostatin flexibility bridges conformations in solution and in the β-tubulin taxane binding site. Journal of the American Chemical Society. 133: 2427-36. PMID 21299225 DOI: 10.1021/Ja1023817  0.44
2010 Zhu A, Zhan W, Liang Z, Yoon Y, Yang H, Grossniklaus HE, Xu J, Rojas M, Lockwood M, Snyder JP, Liotta DC, Shim H. Dipyrimidine amines: A novel class of chemokine receptor type 4 antagonists with high specificity Journal of Medicinal Chemistry. 53: 8556-8568. PMID 21105715 DOI: 10.1021/Jm100786G  0.44
2010 Heathcote DA, Patel H, Kroll SH, Hazel P, Periyasamy M, Alikian M, Kanneganti SK, Jogalekar AS, Scheiper B, Barbazanges M, Blum A, Brackow J, Siwicka A, Pace RD, Fuchter MJ, Snyder JP, et al. A novel pyrazolo[1,5-a]pyrimidine is a potent inhibitor of cyclin-dependent protein kinases 1, 2, and 9, which demonstrates antitumor effects in human tumor xenografts following oral administration. Journal of Medicinal Chemistry. 53: 8508-22. PMID 21080703 DOI: 10.1021/Jm100732T  0.44
2010 Thomas SL, Zhao J, Li Z, Lou B, Du Y, Purcell J, Snyder JP, Khuri FR, Liotta D, Fu H. Activation of the p38 pathway by a novel monoketone curcumin analog, EF24, suggests a potential combination strategy. Biochemical Pharmacology. 80: 1309-16. PMID 20615389 DOI: 10.1016/J.Bcp.2010.06.048  0.44
2010 Chang Y, Ganesh T, Horton JR, Spannhoff A, Liu J, Sun A, Zhang X, Bedford MT, Shinkai Y, Snyder JP, Cheng X. Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases. Journal of Molecular Biology. 400: 1-7. PMID 20434463 DOI: 10.1016/J.Jmb.2010.04.048  0.44
2010 Ndungu JM, Lu YJ, Zhu S, Yang C, Wang X, Chen G, Shin DM, Snyder JP, Shoji M, Sun A. Targeted delivery of paclitaxel to tumor cells: synthesis and in vitro evaluation. Journal of Medicinal Chemistry. 53: 3127-32. PMID 20302303 DOI: 10.1021/Jm901763F  0.32
2010 Chen QH, Ganesh T, Jiang Y, Banerjee A, Sharma S, Bane S, Snyder JP, Kingston DG. Novel epothilone lactones by an unusual diversion of the Grubbs' metathesis reaction. Chemical Communications (Cambridge, England). 46: 2019-21. PMID 20221478 DOI: 10.1039/B926174E  0.44
2010 Hansen KB, Mullasseril P, Dawit S, Kurtkaya NL, Yuan H, Vance KM, Orr AG, Kvist T, Ogden KK, Le P, Vellano KM, Lewis I, Kurtkaya S, Du Y, Qui M, ... ... Snyder JP, et al. Implementation of a fluorescence-based screening assay identifies histamine H3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective N-methyl-D-aspartate receptor antagonists. The Journal of Pharmacology and Experimental Therapeutics. 333: 650-62. PMID 20197375 DOI: 10.1124/Jpet.110.166256  0.44
2010 Dravid SM, Burger PB, Prakash A, Geballe MT, Yadav R, Le P, Vellano K, Snyder JP, Traynelis SF. Structural determinants of D-cycloserine efficacy at the NR1/NR2C NMDA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 2741-54. PMID 20164358 DOI: 10.1523/Jneurosci.5390-09.2010  0.44
2010 Pandey KK, Snyder JP, Liotta DC, Musaev DG. Computational studies of transition metal selectivity of octapeptide repeat region of prion protein (PrP). The Journal of Physical Chemistry. B. 114: 1127-35. PMID 20020721 DOI: 10.1021/Jp909945E  0.44
2010 Prussia AJ, Yang Y, Geballe MT, Snyder JP. Cyclostreptin and microtubules: Is a low-affinity binding site required? Chembiochem. 11: 101-109. PMID 19946930 DOI: 10.1002/Cbic.200900538  0.36
2010 Jogalekar AS, Kriel FH, Shi Q, Cornett B, Cicero D, Snyder JP. The discodermolide hairpin structure flows from conformationally stable modular motifs Journal of Medicinal Chemistry. 53: 155-165. PMID 19894728 DOI: 10.1021/Jm9015284  0.44
2010 Pandey KK, Snyder JP, Liotta DC, Musaev DG. Computational Studies of Transition Metal Selectivity of Octapeptide Repeat Region of Prion Protein (PrP) Journal of Physical Chemistry B. 114: 1127-1135. DOI: 10.1021/jp909945e  0.44
2009 Landais I, Hiddingh S, McCarroll M, Yang C, Sun A, Turker MS, Snyder JP, Hoatlin ME. Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors. Molecular Cancer. 8: 133. PMID 20043851 DOI: 10.1186/1476-4598-8-133  0.32
2009 Escuin D, Burke PA, McMahon-Tobin G, Hembrough T, Wang Y, Alcaraz AA, Leandro-García LJ, Rodríguez-Antona C, Snyder JP, Lavallee TM, Giannakakou P. The hematopoietic-specific beta1-tubulin is naturally resistant to 2-methoxyestradiol and protects patients from drug-induced myelosuppression. Cell Cycle (Georgetown, Tex.). 8: 3914-24. PMID 19901556 DOI: 10.4161/Cc.8.23.10105  0.44
2009 Sun A, Lu YJ, Hu H, Shoji M, Liotta DC, Snyder JP. Curcumin analog cytotoxicity against breast cancer cells: exploitation of a redox-dependent mechanism Bioorganic and Medicinal Chemistry Letters. 19: 6627-6631. PMID 19854644 DOI: 10.1016/J.Bmcl.2009.10.023  0.44
2009 Ducki S, Mackenzie G, Greedy B, Armitage S, Chabert JF, Bennett E, Nettles J, Snyder JP, Lawrence NJ. Combretastatin-like chalcones as inhibitors of microtubule polymerisation. Part 2: Structure-based discovery of alpha-aryl chalcones. Bioorganic & Medicinal Chemistry. 17: 7711-22. PMID 19837594 DOI: 10.1016/J.Bmc.2009.09.044  0.36
2009 Thepchatri P, Min J, Ganesh T, Du Y, Lewis I, Kurtkaya S, Prussia A, Li L, Sneed B, Plemper RK, Fu H, Liotta DC, Snyder JP, Dingledine R, Sun A. Cancer and virus leads by HTS, chemical design and SEA data mining. Current Topics in Medicinal Chemistry. 9: 1159-71. PMID 19807668 DOI: 10.2174/156802609789753581  0.44
2009 Ali S, Heathcote DA, Kroll SH, Jogalekar AS, Scheiper B, Patel H, Brackow J, Siwicka A, Fuchter MJ, Periyasamy M, Tolhurst RS, Kanneganti SK, Snyder JP, Liotta DC, Aboagye EO, et al. The development of a selective cyclin-dependent kinase inhibitor that shows antitumor activity. Cancer Research. 69: 6208-15. PMID 19638587 DOI: 10.1158/0008-5472.Can-09-0301  0.44
2009 Yoon JJ, Krumm SA, Ndungu JM, Hoffman V, Bankamp B, Rota PA, Sun A, Snyder JP, Plemper RK. Target analysis of the experimental measles therapeutic AS-136A. Antimicrobial Agents and Chemotherapy. 53: 3860-70. PMID 19528268 DOI: 10.1128/Aac.00503-09  0.44
2009 Hodge M, Chen QH, Bane S, Sharma S, Loew M, Banerjee A, Alcaraz AA, Snyder JP, Kingston DG. Synthesis and bioactivity of a side chain bridged paclitaxel: A test of the T-Taxol conformation. Bioorganic & Medicinal Chemistry Letters. 19: 2884-7. PMID 19359169 DOI: 10.1016/J.Bmcl.2009.03.063  0.36
2009 Yang Y, Alcaraz AA, Snyder JP. The tubulin-bound conformation of paclitaxel: T-taxol vs "PTX-NY". Journal of Natural Products. 72: 422-9. PMID 19267457 DOI: 10.1021/Np800662J  0.36
2009 Yuan H, Vance KM, Junge CE, Geballe MT, Snyder JP, Hepler JR, Yepes M, Low CM, Traynelis SF. The serine protease plasmin cleaves the amino-terminal domain of the NR2A subunit to relieve zinc inhibition of the N-methyl-D-aspartate receptors. The Journal of Biological Chemistry. 284: 12862-73. PMID 19240037 DOI: 10.1074/Jbc.M805123200  0.44
2009 Chang Y, Zhang X, Horton JR, Upadhyay AK, Spannhoff A, Liu J, Snyder JP, Bedford MT, Cheng X. Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294. Nature Structural & Molecular Biology. 16: 312-7. PMID 19219047 DOI: 10.1038/Nsmb.1560  0.44
2008 Ng FM, Geballe MT, Snyder JP, Traynelis SF, Low CM. Structural insights into phenylethanolamines high-affinity binding site in NR2B from binding and molecular modeling studies. Molecular Brain. 1: 16. PMID 19017396 DOI: 10.1186/1756-6606-1-16  0.44
2008 Tahirovic YA, Geballe M, Gruszecka-Kowalik E, Myers SJ, Lyuboslavsky P, Le P, French A, Irier H, Choi WB, Easterling K, Yuan H, Wilson LJ, Kotloski R, McNamara JO, Dingledine R, ... ... Snyder JP, et al. Enantiomeric propanolamines as selective N-methyl-D-aspartate 2B receptor antagonists. Journal of Medicinal Chemistry. 51: 5506-21. PMID 18800760 DOI: 10.1021/Jm8002153  0.44
2008 Ganesh T, Thepchatri P, Li L, Du Y, Fu H, Snyder JP, Sun A. Synthesis and SAR study of N-(4-hydroxy-3-(2-hydroxynaphthalene-1-yl)phenyl)-arylsulfonamides: heat shock protein 90 (Hsp90) inhibitors with submicromolar activity in an in vitro assay. Bioorganic & Medicinal Chemistry Letters. 18: 4982-7. PMID 18762423 DOI: 10.1016/J.Bmcl.2008.08.022  0.44
2008 Liang Y, Pingali SV, Jogalekar AS, Snyder JP, Thiyagarajan P, Lynn DG. Cross-strand pairing and amyloid assembly. Biochemistry. 47: 10018-26. PMID 18759497 DOI: 10.1021/Bi801081C  0.44
2008 Thomas SL, Zhong D, Zhou W, Malik S, Liotta D, Snyder JP, Hamel E, Giannakakou P. EF24, a novel curcumin analog, disrupts the microtubule cytoskeleton and inhibits HIF-1. Cell Cycle (Georgetown, Tex.). 7: 2409-17. PMID 18682687 DOI: 10.4161/Cc.6410  0.44
2008 Zimmer SM, Liu J, Clayton JL, Stephens DS, Snyder JP. Paclitaxel binding to human and murine MD-2 Journal of Biological Chemistry. 283: 27916-27926. PMID 18650420 DOI: 10.1074/Jbc.M802826200  0.44
2008 Yoon JJ, Chawla D, Paal T, Ndungu M, Du Y, Kurtkaya S, Sun A, Snyder JP, Plemper RK. High-throughput screening-based identification of paramyxovirus inhibitors. Journal of Biomolecular Screening. 13: 591-608. PMID 18626114 DOI: 10.1177/1087057108321089  0.32
2008 Mehta AK, Lu K, Childers WS, Liang Y, Dublin SN, Dong J, Snyder JP, Pingali SV, Thiyagarajan P, Lynn DG. Facial symmetry in protein self-assembly. Journal of the American Chemical Society. 130: 9829-35. PMID 18593163 DOI: 10.1021/Ja801511N  0.44
2008 Kasinski AL, Du Y, Thomas SL, Zhao J, Sun SY, Khuri FR, Wang CY, Shoji M, Sun A, Snyder JP, Liotta D, Fu H. Inhibition of IkappaB kinase-nuclear factor-kappaB signaling pathway by 3,5-bis(2-flurobenzylidene)piperidin-4-one (EF24), a novel monoketone analog of curcumin. Molecular Pharmacology. 74: 654-61. PMID 18577686 DOI: 10.1124/Mol.108.046201  0.44
2008 Ganesh T, Min J, Thepchatri P, Du Y, Li L, Lewis I, Wilson L, Fu H, Chiosis G, Dingledine R, Liotta D, Snyder JP, Sun A. Discovery of aminoquinolines as a new class of potent inhibitors of heat shock protein 90 (Hsp90): Synthesis, biology, and molecular modeling. Bioorganic & Medicinal Chemistry. 16: 6903-10. PMID 18571929 DOI: 10.1016/J.Bmc.2008.05.047  0.44
2008 Sun A, Yoon JJ, Yin Y, Prussia A, Yang Y, Min J, Plemper RK, Snyder JP. Potent non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase complex. Journal of Medicinal Chemistry. 51: 3731-41. PMID 18529043 DOI: 10.1021/Jm701239A  0.36
2008 Lee JK, Prussia A, Paal T, White LK, Snyder JP, Plemper RK. Functional interaction between paramyxovirus fusion and attachment proteins. The Journal of Biological Chemistry. 283: 16561-72. PMID 18426797 DOI: 10.1074/Jbc.M801018200  0.44
2008 Shoji M, Sun A, Kisiel W, Lu YJ, Shim H, McCarey BE, Nichols C, Parker ET, Pohl J, Mosley CA, Alizadeh AR, Liotta DC, Snyder JP. Targeting tissue factor-expressing tumor angiogenesis and tumors with EF24 conjugated to factor VIIa. Journal of Drug Targeting. 16: 185-97. PMID 18365880 DOI: 10.1080/10611860801890093  0.44
2008 Zhan W, Jiang Y, Brodie PJ, Kingston DGI, Liotta DC, Snyder JP. Design and synthesis C6-C8 bridged epothilone a Organic Letters. 10: 1565-1568. PMID 18355076 DOI: 10.1021/Ol800422Q  0.44
2008 Chen PE, Geballe MT, Katz E, Erreger K, Livesey MR, O'Toole KK, Le P, Lee CJ, Snyder JP, Traynelis SF, Wyllie DJ. Modulation of glycine potency in rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes. The Journal of Physiology. 586: 227-45. PMID 17962328 DOI: 10.1113/Jphysiol.2007.143172  0.44
2007 Zhan W, Liang Z, Zhu A, Kurtkaya S, Shim H, Snyder JP, Liotta DC. Discovery of small molecule CXCR4 antagonists Journal of Medicinal Chemistry. 50: 5655-5664. PMID 17958344 DOI: 10.1021/Jm070679I  0.44
2007 Shanker N, Kingston DG, Ganesh T, Yang C, Alcaraz AA, Geballe MT, Banerjee A, McGee D, Snyder JP, Bane S. Enhanced microtubule binding and tubulin assembly properties of conformationally constrained paclitaxel derivatives. Biochemistry. 46: 11514-27. PMID 17892304 DOI: 10.1021/Bi700753Y  0.44
2007 Sun A, Chandrakumar N, Yoon JJ, Plemper RK, Snyder JP. Non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase complex activity: Synthesis and in vitro evaluation. Bioorganic & Medicinal Chemistry Letters. 17: 5199-203. PMID 17643302 DOI: 10.1016/J.Bmcl.2007.06.084  0.32
2007 Erreger K, Geballe MT, Kristensen A, Chen PE, Hansen KB, Lee CJ, Yuan H, Le P, Lyuboslavsky PN, Micale N, Jørgensen L, Clausen RP, Wyllie DJ, Snyder JP, Traynelis SF. Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-D-aspartate glutamate receptors. Molecular Pharmacology. 72: 907-20. PMID 17622578 DOI: 10.1124/Mol.107.037333  0.44
2007 Mosley CA, Liotta DC, Snyder JP. Highly active anticancer curcumin analogues. Advances in Experimental Medicine and Biology. 595: 77-103. PMID 17569206 DOI: 10.1007/978-0-387-46401-5_2  0.44
2007 White LK, Yoon JJ, Lee JK, Sun A, Du Y, Fu H, Snyder JP, Plemper RK. Nonnucleoside inhibitor of measles virus RNA-dependent RNA polymerase complex activity. Antimicrobial Agents and Chemotherapy. 51: 2293-303. PMID 17470652 DOI: 10.1128/Aac.00289-07  0.44
2007 Schafer-Hales K, Iaconelli J, Snyder JP, Prussia A, Nettles JH, El-Naggar A, Khuri FR, Giannakakou P, Marcus AI. Farnesyl transferase inhibitors impair chromosomal maintenance in cell lines and human tumors by compromising CENP-E and CENP-F function. Molecular Cancer Therapeutics. 6: 1317-28. PMID 17431110 DOI: 10.1158/1535-7163.Mct-06-0703  0.44
2007 Wang L, Alcaraz AA, Matesanz R, Yang CG, Barasoain I, Díaz JF, Li YZ, Snyder JP, Fang WS. Synthesis, biological evaluations, and tubulin binding poses of C-2alpha sulfur linked taxol analogues. Bioorganic & Medicinal Chemistry Letters. 17: 3191-4. PMID 17395465 DOI: 10.1016/J.Bmcl.2007.03.026  0.36
2007 Thepchatri P, Eliseo T, Cicero DO, Myles D, Snyder JP. Relationship among ligand conformations in solution, in the solid state, and at the Hsp90 binding site: geldanamycin and radicicol. Journal of the American Chemical Society. 129: 3127-34. PMID 17323946 DOI: 10.1021/Ja064863P  0.44
2007 Ganesh T, Yang C, Norris A, Glass T, Bane S, Ravindra R, Banerjee A, Metaferia B, Thomas SL, Giannakakou P, Alcaraz AA, Lakdawala AS, Snyder JP, Kingston DG. Evaluation of the tubulin-bound paclitaxel conformation: synthesis, biology, and SAR studies of C-4 to C-3' bridged paclitaxel analogues. Journal of Medicinal Chemistry. 50: 713-25. PMID 17263521 DOI: 10.1021/Jm061071X  0.44
2007 Paik Y, Yang C, Metaferia B, Tang S, Bane S, Ravindra R, Shanker N, Alcaraz AA, Johnson SA, Schaefer J, O'Connor RD, Cegelski L, Snyder JP, Kingston DG. Rotational-echo double-resonance NMR distance measurements for the tubulin-bound Paclitaxel conformation. Journal of the American Chemical Society. 129: 361-70. PMID 17212416 DOI: 10.1021/Ja0656604  0.44
2006 Sun A, Prussia A, Zhan W, Murray EE, Doyle J, Cheng LT, Yoon JJ, Radchenko EV, Palyulin VA, Compans RW, Liotta DC, Plemper RK, Snyder JP. Nonpeptide inhibitors of measles virus entry Journal of Medicinal Chemistry. 49: 5080-5092. PMID 16913698 DOI: 10.1021/Jm0602559  0.44
2006 Sun A, Shoji M, Lu YJ, Liotta DC, Snyder JP. Synthesis of EF24-tripeptide chloromethyl ketone: A novel curcumin-related anticancer drug delivery system Journal of Medicinal Chemistry. 49: 3153-3158. PMID 16722634 DOI: 10.1021/Jm051141K  0.44
2006 Alcaraz AA, Mehta AK, Johnson SA, Snyder JP. The T-Taxol conformation. Journal of Medicinal Chemistry. 49: 2478-88. PMID 16610791 DOI: 10.1021/Jm051119R  0.36
2006 Jiang Y, Alcaraz AA, Chen JM, Kobayashi H, Lu YJ, Snyder JP. Diastereomers of dibromo-7-epi-10-deacetylcephalomannine: crowded and cytotoxic taxanes exhibit halogen bonds. Journal of Medicinal Chemistry. 49: 1891-9. PMID 16539375 DOI: 10.1021/Jm0509243  0.36
2006 Ganesh T, Norris A, Sharma S, Bane S, Alcaraz AA, Snyder JP, Kingston DG. Design, synthesis, and bioactivity of simplified paclitaxel analogs based on the T-Taxol bioactive conformation. Bioorganic & Medicinal Chemistry. 14: 3447-54. PMID 16434198 DOI: 10.1016/J.Bmc.2006.01.002  0.44
2006 Doyle J, Prussia A, White LK, Sun A, Liotta DC, Snyder JP, Compans RW, Plemper RK. Two domains that control prefusion stability and transport competence of the measles virus fusion protein. Journal of Virology. 80: 1524-36. PMID 16415028 DOI: 10.1128/Jvi.80.3.1524-1536.2006  0.44
2006 Kristensen AS, Geballe MT, Snyder JP, Traynelis SF. Glutamate receptors: variation in structure-function coupling. Trends in Pharmacological Sciences. 27: 65-9. PMID 16406088 DOI: 10.1016/J.Tips.2005.12.005  0.44
2006 Zysman-Colman E, Nevins N, Eghbali N, Snyder JP, Harpp DN. Crossover point between dialkoxy disulfides (ROSSOR) and thionosulfites ((RO)2S=S): prediction, synthesis, and structure. Journal of the American Chemical Society. 128: 291-304. PMID 16390159 DOI: 10.1021/Ja0559395  0.44
2005 Kim W, McMillan RA, Snyder JP, Conticello VP. A stereoelectronic effect on turn formation due to proline substitution in elastin-mimetic polypeptides. Journal of the American Chemical Society. 127: 18121-32. PMID 16366565 DOI: 10.1021/Ja054105J  0.44
2005 Johnson SA, Alcaraz AA, Snyder JP. T-Taxol and the electron crystallographic density in beta-tubulin. Organic Letters. 7: 5549-52. PMID 16320988 DOI: 10.1021/Ol051780P  0.36
2005 Thepchatri P, Cicero DO, Monteagudo E, Ghosh AK, Cornett B, Weeks ER, Snyder JP. Conformations of laulimalide in DMSO-d6. Journal of the American Chemical Society. 127: 12838-46. PMID 16159277 DOI: 10.1021/Ja042890E  0.44
2005 Plemper RK, Doyle J, Sun A, Prussia A, Cheng LT, Rota PA, Liotta DC, Snyder JP, Compans RW. Design of a small-molecule entry inhibitor with activity against primary measles virus strains Antimicrobial Agents and Chemotherapy. 49: 3755-3761. PMID 16127050 DOI: 10.1128/Aac.49.9.3755-3761.2005  0.44
2005 Erreger K, Geballe MT, Dravid SM, Snyder JP, Wyllie DJ, Traynelis SF. Mechanism of partial agonism at NMDA receptors for a conformationally restricted glutamate analog. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 7858-66. PMID 16120788 DOI: 10.1523/Jneurosci.1613-05.2005  0.44
2005 Adams BK, Cai J, Armstrong J, Herold M, Lu YJ, Sun A, Snyder JP, Liotta DC, Jones DP, Shoji M. EF24, a novel synthetic curcumin analog, induces apoptosis in cancer cells via a redox-dependent mechanism Anti-Cancer Drugs. 16: 263-275. PMID 15711178 DOI: 10.1097/00001813-200503000-00005  0.44
2005 Chen PE, Geballe MT, Stansfeld PJ, Johnston AR, Yuan H, Jacob AL, Snyder JP, Traynelis SF, Wyllie DJ. Structural features of the glutamate binding site in recombinant NR1/NR2A N-methyl-D-aspartate receptors determined by site-directed mutagenesis and molecular modeling. Molecular Pharmacology. 67: 1470-84. PMID 15703381 DOI: 10.1124/Mol.104.008185  0.44
2005 Sun A, Lankin DC, Hardcastle K, Snyder JP. 3-Fluoropiperidines and N-methyl-3-fluoropiperidinium salts: the persistence of axial fluorine. Chemistry (Weinheim An Der Bergstrasse, Germany). 11: 1579-91. PMID 15662680 DOI: 10.1002/Chem.200400835  0.44
2005 Liu C, Tamm M, Nötzel MW, Rauch K, De Meijere A, Schilling JK, Lakdawala A, Snyder JP, Bane SL, Shanker N, Ravindra R, Kingston DGI. C-3′-cyclopropanated taxol analogs: Synthesis, bioassay and biostructural analysis European Journal of Organic Chemistry. 3962-3972. DOI: 10.1002/Ejoc.200500243  0.44
2004 Watson RT, Gore VK, Chandupatla KR, Dieter RK, Snyder JP. Synthesis of (-)-(R)-pyrrolam a and studies on its stability: a caveat on computational methods. The Journal of Organic Chemistry. 69: 6105-14. PMID 15373496 DOI: 10.1021/Jo049460R  0.44
2004 Nettles JH, Li H, Cornett B, Krahn JM, Snyder JP, Downing KH. The binding mode of epothilone A on alpha,beta-tubulin by electron crystallography. Science (New York, N.Y.). 305: 866-9. PMID 15297674 DOI: 10.1126/Science.1099190  0.44
2004 Ganesh T, Guza RC, Bane S, Ravindra R, Shanker N, Lakdawala AS, Snyder JP, Kingston DG. The bioactive Taxol conformation on beta-tubulin: experimental evidence from highly active constrained analogs. Proceedings of the National Academy of Sciences of the United States of America. 101: 10006-11. PMID 15226503 DOI: 10.1073/Pnas.0403459101  0.44
2004 Adams BK, Ferstl EM, Davis MC, Herold M, Kurtkaya S, Camalier RF, Hollingshead MG, Kaur G, Sausville EA, Rickles FR, Snyder JP, Liotta DC, Shoji M. Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents Bioorganic and Medicinal Chemistry. 12: 3871-3883. PMID 15210154 DOI: 10.1016/J.Bmc.2004.05.006  0.44
2004 Kelso MJ, Beyer RL, Hoang HN, Lakdawala AS, Snyder JP, Oliver WV, Robertson TA, Appleton TG, Fairlie DP. Alpha-turn mimetics: short peptide alpha-helices composed of cyclic metallopentapeptide modules. Journal of the American Chemical Society. 126: 4828-42. PMID 15080687 DOI: 10.1021/Ja037980I  0.44
2004 Plemper RK, Erlandson KJ, Lakdawala AS, Sun A, Prussia A, Boonsombat J, Aki-Sener E, Yalcin I, Yildiz I, Temiz-Arpaci O, Tekiner B, Liotta DC, Snyder JP, Compans RW. A target site for template-based design of measles virus entry inhibitors Proceedings of the National Academy of Sciences of the United States of America. 101: 5628-5633. PMID 15056763 DOI: 10.1073/Pnas.0308520101  0.44
2004 Barboni L, Giarlo G, Ricciutelli M, Ballini R, Georg GI, VanderVelde DG, Himes RH, Wang M, Lakdawala A, Snyder JP. Synthesis, modeling, and anti-tubulin activity of a D-seco paclitaxel analogue. Organic Letters. 6: 461-4. PMID 14961598 DOI: 10.1021/Ol036204C  0.44
2004 Downing KH, Li H, Nettles JH, Snyder JP. Studies of ligand binding to tubulin by electron crystallography Microscopy and Microanalysis. 10: 1500-1501. DOI: 10.1017/S1431927604882941  0.44
2003 Haack T, Kurtkaya S, Snyder JP, Georg GI. Studies toward the synthesis of oximidines I and II. Organic Letters. 5: 5019-22. PMID 14682754 DOI: 10.1021/Ol036007D  0.44
2003 Checchi PM, Nettles JH, Zhou J, Snyder JP, Joshi HC. Microtubule-interacting drugs for cancer treatment. Trends in Pharmacological Sciences. 24: 361-5. PMID 12871669 DOI: 10.1016/S0165-6147(03)00161-5  0.44
2003 Plemper RK, Lakdawala AS, Gernert KM, Snyder JP, Compans RW. Structural features of paramyxovirus F protein required for fusion initiation. Biochemistry. 42: 6645-55. PMID 12779319 DOI: 10.1021/Bi034385K  0.32
2003 Ambhaikar NB, Snyder JP, Liotta DC. Diastereoselective addition of chlorotitanium enolate of N-acyl thiazolidinethione to O-methyl oximes: A novel, stereoselective synthesis of α,β-disubstituted β-amino carbonyl compounds via chiral auxiliary mediated azetine formation Journal of the American Chemical Society. 125: 3690-3691. PMID 12656586 DOI: 10.1021/Ja029871U  0.44
2003 Lynn DG, Snyder JP, Lakdawala AS, Dong J, Lu K. Conformational evolution: the wiggling of peptides into amyloid. Structure (London, England : 1993). 11: 242. PMID 12623011 DOI: 10.1016/S0969-2126(03)00035-2  0.44
2003 Snyder JP, Lakdawala AS, Kelso MJ. On the stability of a single-turn alpha-helix: the single versus multiconformation problem. Journal of the American Chemical Society. 125: 632-3. PMID 12526653 DOI: 10.1021/Ja0278279  0.32
2002 Lakdawala AS, Morgan DM, Liotta DC, Lynn DG, Snyder JP. Dynamics and fluidity of amyloid fibrils: a model of fibrous protein aggregates. Journal of the American Chemical Society. 124: 15150-1. PMID 12487571 DOI: 10.1021/Ja0273290  0.44
2002 Lankin DC, Grunewald GL, Romero FA, Oren IY, Snyder JP. The NH---FC dipole orientation effect for pendant exocyclic CH(2)F. Organic Letters. 4: 3557-60. PMID 12375886 DOI: 10.1021/ol026358c  0.44
2002 Priefer R, Lee YJ, Barrios F, Wosnick JH, Lebuis AM, Farrell PG, Harpp DN, Sun A, Wu S, Snyder JP. Dicubyl disulfide. Journal of the American Chemical Society. 124: 5626-7. PMID 12010021 DOI: 10.1021/ja025823y  0.44
2002 Ferstl EM, Venkatesan H, Ambhaikar NB, Snyder JP, Liotta DC. Thiazolidine-2-thione directed diastereoselective addition of chlorotitanium enolates to aldimines Synthesis. 2075-2083. DOI: 10.1055/S-2002-34375  0.44
2002 Morgan DM, Lynn DG, Lakdawala AS, Snyder JP, Liotta DC. Amyloid structure: Models and theoretical considerations in fibrous aggregates Journal of the Chinese Chemical Society. 49: 459-466. DOI: 10.1002/Jccs.200200072  0.44
2001 Lakdawala A, Wang M, Nevins N, Liotta DC, Rusinska-Roszak D, Lozynski M, Snyder JP. Calculated conformer energies for organic molecules with multiple polar functionalities are method dependent: Taxol (case study). Bmc Chemical Biology. 1: 2. PMID 11710970 DOI: 10.1186/1472-6769-1-2  0.44
2001 Snyder JP, Padwa A, Stengel T, Arduengo AJ, Jockisch A, Kim HJ. A stable dirhodium tetracarboxylate carbenoid: crystal structure, bonding analysis, and catalysis. Journal of the American Chemical Society. 123: 11318-9. PMID 11697986 DOI: 10.1021/Ja016928O  0.44
2001 Metaferia BB, Hoch J, Glass TE, Bane SL, Chatterjee SK, Snyder JP, Lakdawala A, Cornett B, Kingston DG. Synthesis and biological evaluation of novel macrocyclic paclitaxel analogues. Organic Letters. 3: 2461-4. PMID 11483035 DOI: 10.1021/Ol016124D  0.44
2001 Judd DA, Nettles JH, Nevins N, Snyder JP, Liotta DC, Tang J, Ermolieff J, Schinazi RF, Hill CL. Polyoxometalate HIV-1 protease inhibitors. A new mode of protease inhibition Journal of the American Chemical Society. 123: 886-897. PMID 11456622 DOI: 10.1021/Ja001809E  0.44
2001 Monteagudo E, Cicero DO, Cornett B, Myles DC, Snyder JP. The conformations of discodermolide in DMSO Journal of the American Chemical Society. 123: 6929-6930. PMID 11448201 DOI: 10.1021/Ja015569U  0.44
2001 Venkatesan H, Davis MC, Altas Y, Snyder JP, Liotta DC. Total synthesis of SR 121463 A, a highly potent and selective vasopressin V2 receptor antagonist Journal of Organic Chemistry. 66: 3653-3661. PMID 11374981 DOI: 10.1021/Jo0004658  0.44
2001 Barboni L, Datta A, Dutta D, Georg GI, Vander Velde DG, Himes RH, Wang M, Snyder JP. Novel d-seco paclitaxel analogues: synthesis, biological evaluation, and model testing. The Journal of Organic Chemistry. 66: 3321-9. PMID 11348113 DOI: 10.1021/Jo0015467  0.44
2001 Barboni L, Lambertucci C, Appendino G, Vander Velde DG, Himes RH, Bombardelli E, Wang M, Snyder JP. Synthesis and NMR-driven conformational analysis of taxol analogues conformationally constrained on the C13 side chain. Journal of Medicinal Chemistry. 44: 1576-87. PMID 11334567 DOI: 10.1021/Jm001103V  0.44
2001 Snyder JP, Nettles JH, Cornett B, Downing KH, Nogales E. The binding conformation of Taxol in beta-tubulin: a model based on electron crystallographic density. Proceedings of the National Academy of Sciences of the United States of America. 98: 5312-6. PMID 11309480 DOI: 10.1073/Pnas.051309398  0.44
2000 Wang M, Cornett B, Nettles J, Liotta DC, Snyder JP. The oxetane ring in Taxol Journal of Organic Chemistry. 65: 1059-1068. PMID 10814054 DOI: 10.1021/Jo9916075  0.44
2000 White JD, Demnitz FWJ, Oda H, Hassler C, Snyder JP. Conformational study of the intramolecular Diels-Alder reaction of a pentadienyl acrylate. Theoretical evaluation of kinetic and thermodynamic control Organic Letters. 2: 3313-3316. DOI: 10.1021/Ol000200F  0.44
2000 Snyder JP, Nevins N, Cicero DO, Jansen J. The conformations of taxol in chloroform [7] Journal of the American Chemical Society. 122: 724-725. DOI: 10.1021/Ja9930115  0.44
2000 Padwa A, Snyder JP, Curtis EA, Sheehan SM, Worsencroft KJ, Kappe CO. Rhodium(II)-catalyzed equilibration of push-pull carbonyl and ammonium ylides. A computationally based understanding of the reaction pathway Journal of the American Chemical Society. 122: 8155-8167. DOI: 10.1021/Ja001088J  0.44
1999 Wang M, Xia X, Kim Y, Hwang D, Jansen JM, Botta M, Liotta DC, Snyder JP. A unified and quantitative receptor model for the microtubule binding of paclitaxel and epothilone Organic Letters. 1: 43-46. PMID 10822530 DOI: 10.1021/Ol990521V  0.44
1999 Nevins N, Cicero D, Snyder JP. A test of the single-conformation hypothesis in the analysis of NMR data for small polar molecules: A force field comparison Journal of Organic Chemistry. 64: 3979-3986. DOI: 10.1021/Jo9824450  0.44
1999 Davis MC, Cornett B, Wu S, Snyder JP. On 'pure axial' monosubstituted cyclohexanes: Cyclohexyl nitronate esters adopt O-equatorial conformations Journal of the American Chemical Society. 121: 11864-11870. DOI: 10.1021/Ja993017U  0.44
1998 Bertz SH, Nilsson K, Davidsson Ö, Snyder JP. The Use of N NMR Spectroscopy To Resolve the "Higher Order Cyanocuprate" Controversy: N, Li, and C NMR Spectroscopic Investigations of CuCN-Derived Butyl Cuprates. Angewandte Chemie (International Ed. in English). 37: 314-317. PMID 29711247 DOI: 10.1002/(Sici)1521-3773(19980216)37:3<314::Aid-Anie314>3.0.Co;2-T  0.12
1997 Padwa A, Kappe CO, Cochran JE, Snyder JP. Studies Dealing with the Cycloaddition/Ring Opening/Elimination Sequence of 2-Amino-Substituted Isobenzofurans. The Journal of Organic Chemistry. 62: 2786-2797. PMID 11671641 DOI: 10.1021/jo962358c  0.44
1997 Jansen JM, Koehler KF, Hedberg MH, Johansson AM, Hacksell U, Nordvall G, Snyder JP. Molecular design using the minireceptor concept Journal of Chemical Information and Computer Sciences. 37: 812-818. PMID 9254913 DOI: 10.1021/Ci960110I  0.44
1997 Frantz DE, Singleton DA, Snyder JP. 13C kinetic isotope effects for the addition of lithium dibutylcuprate to cyclohexenone. Reductive elimination is rate-determining Journal of the American Chemical Society. 119: 3383-3384. DOI: 10.1021/Ja9636348  0.44
1996 Bertz SH, Eriksson M, Miao G, Snyder JP. β-Silyl organocuprates: The grail of organocuprate chemistry? Journal of the American Chemical Society. 118: 10906-10907. DOI: 10.1021/Ja962559Y  0.44
1996 Huang H, Alvarez K, Lui Q, Barnhart TM, Snyder JP, Penner-Hahn JE. Infrared spectroscopic characterization of cyanocuprates Journal of the American Chemical Society. 118: 8808-8816. DOI: 10.1021/Ja961862W  0.44
1996 Lipshutz BH, Stevens KL, James B, Pavlovich JG, Snyder JP. Analyses of anionic Cu(I) complexes via electrospray mass spectrometry Journal of the American Chemical Society. 118: 6796-6797. DOI: 10.1021/Ja960182Q  0.44
1995 Snyder JP, Bertz SH. "Higher order" cyanocuprate structure: Cyanide is lithium bound Journal of Organic Chemistry. 60: 4312-4313. DOI: 10.1021/Jo00119A002  0.44
1991 Murakami Y, Kikuchi JI, Ohno T, Hirayama T, Hisaeda Y, Nishimura H, Snyder JP, Steliou K. Syntheses of Macrocyclic Enzyme Models. 8. Conformational Mobility and Molecular Recognition by the Internal Cage of Kyuphane Journal of the American Chemical Society. 113: 8229-8242.  0.44
1988 Koschmann T, Snyder JP, Johnson P, Grace T, Evens MW. Conformational analysis using a truth maintenance system Journal of Molecular Graphics. 6: 74-79. DOI: 10.1016/0263-7855(88)85003-3  0.44
1986 Thorsett ED, Harris EE, Aster SD, Peterson ER, Snyder JP, Springer JP, Hirshfield J, Tristram EW, Patchett AA, Ulm EH. Conformationally restricted inhibitors of angiotensin converting enzyme: synthesis and computations. Journal of Medicinal Chemistry. 29: 251-60. PMID 3005569  0.44
1978 Snyder JP, Harpp DN. Conformational analysis of acyclic trisulfides: HSSSH and CH3SSSCH3 Tetrahedron Letters. 19: 197-200. DOI: 10.1016/S0040-4039(01)85083-8  0.44
1973 Heyman ML, Snyder JP. An efficient synthesis of bicyclic hydrazines and azo alkanes Tetrahedron Letters. 14: 2859-2862. DOI: 10.1016/S0040-4039(01)96071-X  0.44
1971 Heyman M, Bandurco VT, Snyder JP. Azoalkane synthesis by direct oxidation of semicarbazides with copper halide Journal of the Chemical Society D: Chemical Communications. 297-298. DOI: 10.1039/C29710000297  0.44
1971 Snyder JP, Heyman ML, Bandurco VT, Harpp DN. Mass spectrometric behavior of cis-2,3-diazabicyclo alkane derivatives at differential oxidation levels Tetrahedron Letters. 12: 4693-4696. DOI: 10.1016/S0040-4039(01)97564-1  0.44
1970 Harpp DN, Ash DK, Back TG, Gleason JG, Orwig BA, VanHorn WF, Snyder JP. A new synthesis of unsymmetrical disulfides Tetrahedron Letters. 11: 3551-3554. DOI: 10.1016/S0040-4039(01)98525-9  0.44
1968 Harpp DN, Gleason JG, Snyder JP. Organic sulfur chemistry. I. The disulfide-phosphine reaction. Desulfurization with tris(diethylamino)phosphine [18] Journal of the American Chemical Society. 90: 4181-4182. DOI: 10.1021/Ja01017A060  0.44
1966 Snyder JP, Farnum DG. Determination of the configuration of tricyclo[,5]-7-decenes by means of vinyl proton nuclear magnetic resonance Journal of Organic Chemistry. 31: 1699-1702. DOI: 10.1021/Jo01344A007  0.44
1965 Farnum DG, Snyder JP. Bromination of tricyclo[,5] deca-3,7-dienes. Depression of transannular double bond participation by the presence of electronegative substituents. Tetrahedron Letters. 6: 3861-3867.  0.44
Show low-probability matches.