Year |
Citation |
Score |
2023 |
Ahmed M, Spicer C, Harley J, Taylor JP, Hanna M, Patani R, Greensmith L. Amplifying the Heat Shock Response Ameliorates ALS and FTD Pathology in Mouse and Human Models. Molecular Neurobiology. PMID 37516663 DOI: 10.1007/s12035-023-03509-2 |
0.309 |
|
2023 |
Fisher EMC, Greensmith L, Malaspina A, Fratta P, Hanna MG, Schiavo G, Isaacs AM, Orrell RW, Cunningham TJ, Arozena AA. Opinion: more mouse models and more translation needed for ALS. Molecular Neurodegeneration. 18: 30. PMID 37143081 DOI: 10.1186/s13024-023-00619-2 |
0.499 |
|
2020 |
Bendotti C, Bonetto V, Pupillo E, Logroscino G, Al-Chalabi A, Lunetta C, Riva N, Mora G, Lauria G, Weishaupt JH, Agosta F, Malaspina A, Basso M, Greensmith L, Van Den Bosch L, et al. Focus on the heterogeneity of amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-11. PMID 32583689 DOI: 10.1080/21678421.2020.1779298 |
0.386 |
|
2020 |
Gray AL, Annan L, Dick JRT, La Spada AR, Hanna MG, Greensmith L, Malik B. Deterioration of muscle force and contractile characteristics are early pathological events in spinal and bulbar muscular atrophy mice. Disease Models & Mechanisms. PMID 32152060 DOI: 10.1242/Dmm.042424 |
0.418 |
|
2020 |
Fellows AD, Rhymes ER, Gibbs KL, Greensmith L, Schiavo G. IGF1R regulates retrograde axonal transport of signalling endosomes in motor neurons. Embo Reports. e49129. PMID 32030864 DOI: 10.15252/Embr.201949129 |
0.584 |
|
2019 |
Lombardi V, Bombaci A, Zampedri L, Lu CH, Malik B, Zetterberg H, Heslegrave AJ, Rinaldi C, Greensmith L, Hanna MG, Malaspina A, Fratta P. Plasma pNfH levels differentiate SBMA from ALS. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 31575607 DOI: 10.1136/Jnnp-2019-320624 |
0.37 |
|
2019 |
Klickovic U, Zampedri L, Sinclair CDJ, Wastling SJ, Trimmel K, Howard RS, Malaspina A, Sharma N, Sidle K, Emira A, Shah S, Yousry TA, Hanna MG, Greensmith L, Morrow JM, et al. Skeletal muscle MRI differentiates SBMA and ALS and correlates with disease severity. Neurology. PMID 31391248 DOI: 10.1212/Wnl.0000000000008009 |
0.405 |
|
2019 |
Tyzack GE, Luisier R, Taha DM, Neeves J, Modic M, Mitchell JS, Meyer I, Greensmith L, Newcombe J, Ule J, Luscombe NM, Patani R. Widespread FUS mislocalization is a molecular hallmark of amyotrophic lateral sclerosis. Brain : a Journal of Neurology. PMID 31368485 DOI: 10.1093/Brain/Awz217 |
0.368 |
|
2019 |
Clarke BE, Gil RS, Yip J, Kalmar B, Greensmith L. Regional differences in the inflammatory and heat shock response in glia: implications for ALS. Cell Stress & Chaperones. PMID 31168740 DOI: 10.1007/S12192-019-01005-Y |
0.361 |
|
2019 |
Malik B, Devine H, Patani R, La Spada AR, Hanna MG, Greensmith L. Gene expression analysis reveals early dysregulation of disease pathways and links Chmp7 to pathogenesis of spinal and bulbar muscular atrophy. Scientific Reports. 9: 3539. PMID 30837566 DOI: 10.1038/S41598-019-40118-3 |
0.403 |
|
2019 |
Lombardi V, Querin G, Ziff OJ, Zampedri L, Martinelli I, Heller C, Foiani M, Bertolin C, Lu CH, Malik B, Allen K, Rinaldi C, Zetterberg H, Heslegrave A, Greensmith L, et al. Muscle and not neuronal biomarkers correlate with severity in spinal and bulbar muscular atrophy. Neurology. PMID 30787165 DOI: 10.1212/Wnl.0000000000007097 |
0.352 |
|
2018 |
Zubiri I, Lombardi V, Bremang M, Mitra V, Nardo G, Adiutori R, Lu CH, Leoni E, Yip P, Yildiz O, Ward M, Greensmith L, Bendotti C, Pike I, Malaspina A. Tissue-enhanced plasma proteomic analysis for disease stratification in amyotrophic lateral sclerosis. Molecular Neurodegeneration. 13: 60. PMID 30404656 DOI: 10.1186/S13024-018-0292-2 |
0.35 |
|
2018 |
Zucchi E, Lu CH, Cho Y, Chang R, Adiutori R, Zubiri I, Ceroni M, Cereda C, Pansarasa O, Greensmith L, Malaspina A, Petzold A. A motor neuron strategy to save time and energy in neurodegeneration: adaptive protein stoichiometry. Journal of Neurochemistry. PMID 29959860 DOI: 10.1111/Jnc.14542 |
0.32 |
|
2018 |
Luisier R, Tyzack GE, Hall CE, Mitchell JS, Devine H, Taha DM, Malik B, Meyer I, Greensmith L, Newcombe J, Ule J, Luscombe NM, Patani R. Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS. Nature Communications. 9: 2010. PMID 29789581 DOI: 10.1038/S41467-018-04373-8 |
0.386 |
|
2018 |
Gibbs KL, Kalmar B, Rhymes ER, Fellows AD, Ahmed M, Whiting P, Davies CH, Greensmith L, Schiavo G. Inhibiting p38 MAPK alpha rescues axonal retrograde transport defects in a mouse model of ALS. Cell Death & Disease. 9: 596. PMID 29789529 DOI: 10.1038/S41419-018-0624-8 |
0.603 |
|
2018 |
Wilson ER, Kugathasan U, Abramov AY, Clark AJ, Bennett DLH, Reilly MM, Greensmith L, Kalmar B. Hereditary sensory neuropathy type 1-associated deoxysphingolipids cause neurotoxicity, acute calcium handling abnormalities and mitochondrial dysfunction in vitro. Neurobiology of Disease. PMID 29778900 DOI: 10.1016/J.Nbd.2018.05.008 |
0.348 |
|
2018 |
Fratta P, Sivakumar P, Humphrey J, Lo K, Ricketts T, Oliveira H, Brito-Armas JM, Kalmar B, Ule A, Yu Y, Birsa N, Bodo C, Collins T, Conicella AE, Mejia Maza A, ... ... Greensmith L, et al. Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis. The Embo Journal. PMID 29764981 DOI: 10.15252/Embj.201798684 |
0.368 |
|
2018 |
Watson-Scales S, Kalmar B, Lana-Elola E, Gibbins D, La Russa F, Wiseman F, Williamson M, Saccon R, Slender A, Olerinyova A, Mahmood R, Nye E, Cater H, Wells S, Yu YE, ... ... Greensmith L, et al. Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration. Plos Genetics. 14: e1007383. PMID 29746474 DOI: 10.1371/Journal.Pgen.1007383 |
0.355 |
|
2018 |
Bennett CL, Dastidar SG, Ling SC, Malik B, Ashe T, Wadhwa M, Miller DB, Lee C, Mitchell MB, van Es MA, Grunseich C, Chen Y, Sopher BL, Greensmith L, Cleveland DW, et al. Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in ALS4 mice and human patients. Acta Neuropathologica. PMID 29725819 DOI: 10.1007/S00401-018-1852-9 |
0.452 |
|
2018 |
Acevedo-Arozena A, Devoy A, Cunningham TJ, Isaacs AM, Greensmith L, Fratta P, Fisher EM. Knock in mouse models to understand ALS pathomechanisms F1000research. 7. DOI: 10.7490/F1000Research.1116336.1 |
0.304 |
|
2018 |
Ziff O, Lombardi V, Zampedri L, Querin G, Bertolin C, Greensmith L, Hanna M, Zetterberg H, Heslegrave A, Soraru G, Malaspina A, Fratta P. Muscle and neuronal peripheral biomarkers for spinal and bulbar muscle atrophy: muscle holds more promise Neuromuscular Disorders. 28. DOI: 10.1016/S0960-8966(18)30367-5 |
0.336 |
|
2018 |
Devine H, Malik B, Mitchell J, Greensmith L, Patani R. Establishing motor neuron and astrocytic cultures to study spinal and bulbar muscular atrophy Neuromuscular Disorders. 28: S24-S25. DOI: 10.1016/S0960-8966(18)30362-6 |
0.348 |
|
2018 |
Sarajarvi V, Kalmar B, Fernandes I, Reilly M, Greensmith L. Do diverse Charcot-Marie-Tooth disease-causing mutations show convergent disease pathomechanisms? Investigation of mitochondrial dysfunction in CMT Neuromuscular Disorders. 28: S23. DOI: 10.1016/S0960-8966(18)30357-2 |
0.304 |
|
2017 |
Bondulich MK, Jolinon N, Osborne GF, Smith EJ, Rattray I, Neueder A, Sathasivam K, Ahmed M, Ali N, Benjamin AC, Chang X, Dick JRT, Ellis M, Franklin SA, Goodwin D, ... ... Greensmith L, et al. Myostatin inhibition prevents skeletal muscle pathophysiology in Huntington's disease mice. Scientific Reports. 7: 14275. PMID 29079832 DOI: 10.1038/S41598-017-14290-3 |
0.375 |
|
2017 |
Devoy A, Kalmar B, Stewart M, Park H, Burke B, Noy SJ, Redhead Y, Humphrey J, Lo K, Jaeger J, Mejia Maza A, Sivakumar P, Bertolin C, Soraru G, Plagnol V, ... Greensmith L, et al. Humanized mutant FUS drives progressive motor neuron degeneration without aggregation in 'FUSDelta14' knockin mice. Brain : a Journal of Neurology. PMID 29053787 DOI: 10.1093/Brain/Awx248 |
0.442 |
|
2017 |
Kalmar B, Greensmith L. Cellular Chaperones As Therapeutic Targets in ALS to Restore Protein Homeostasis and Improve Cellular Function. Frontiers in Molecular Neuroscience. 10: 251. PMID 28943839 DOI: 10.3389/Fnmol.2017.00251 |
0.382 |
|
2017 |
Kalmar B, Innes A, Wanisch K, Koyen Kolaszynska A, Pandraud A, Kelly G, Abramov AY, Reilly MM, Schiavo G, Greensmith L. Mitochondrial deficits and abnormal mitochondrial retrograde axonal transport play a role in the pathogenesis of mutant Hsp27 induced Charcot Marie Tooth Disease. Human Molecular Genetics. PMID 28595321 DOI: 10.1093/Hmg/Ddx216 |
0.584 |
|
2017 |
Soares D, Goldrick I, Lemon RN, Kraskov A, Greensmith L, Kalmar B. Expression of Kv3.1b potassium channel is widespread in macaque motor cortex pyramidal cells: A histological comparison between rat and macaque. The Journal of Comparative Neurology. PMID 28213922 DOI: 10.1002/Cne.24192 |
0.311 |
|
2017 |
Clarke B, Kalmar B, Greensmith L. Characterisation of the heat shock response in primary and ES-cell derived spinal motor neurons and astrocytes exposed to cellular stress conditions modelling ALS Neuromuscular Disorders. 27: S28. DOI: 10.1016/S0960-8966(17)30302-4 |
0.367 |
|
2016 |
Smith AS, Passey SL, Martin NR, Player DJ, Mudera V, Greensmith L, Lewis MP. Creating Interactions between Tissue-Engineered Skeletal Muscle and the Peripheral Nervous System. Cells, Tissues, Organs. 202: 143-158. PMID 27825148 DOI: 10.1159/000443634 |
0.36 |
|
2016 |
Lu CH, Allen K, Oei F, Leoni E, Kuhle J, Tree T, Fratta P, Sharma N, Sidle K, Howard R, Orrell R, Fish M, Greensmith L, Pearce N, Gallo V, et al. Systemic inflammatory response and neuromuscular involvement in amyotrophic lateral sclerosis. Neurology® Neuroimmunology & Neuroinflammation. 3: e244. PMID 27308305 DOI: 10.1212/Nxi.0000000000000244 |
0.302 |
|
2016 |
Bryson JB, Machado CB, Lieberam I, Greensmith L. Restoring motor function using optogenetics and neural engraftment. Current Opinion in Biotechnology. 40: 75-81. PMID 27016703 DOI: 10.1016/J.Copbio.2016.02.016 |
0.397 |
|
2016 |
Rossor AM, Liu CH, Petzold A, Malaspina A, Laura M, Greensmith L, Reilly MM. Plasma neurofilament heavy chain is not a useful biomarker in Charcot-Marie-Tooth Disease. Muscle & Nerve. PMID 27015106 DOI: 10.1002/Mus.25124 |
0.306 |
|
2016 |
Ahmed M, Machado PM, Miller A, Spicer C, Herbelin L, He J, Noel J, Wang Y, McVey AL, Pasnoor M, Gallagher P, Statland J, Lu CH, Kalmar B, Brady S, ... ... Greensmith L, et al. Targeting protein homeostasis in sporadic inclusion body myositis. Science Translational Medicine. 8: 331ra41. PMID 27009270 DOI: 10.1126/Scitranslmed.Aad4583 |
0.556 |
|
2016 |
Rinaldi C, Malik B, Greensmith L. Targeted Molecular Therapies for SBMA. Journal of Molecular Neuroscience : Mn. 58: 335-42. PMID 26576772 DOI: 10.1007/S12031-015-0676-5 |
0.38 |
|
2016 |
Gibbs KL, Kalmar B, Sleigh JN, Greensmith L, Schiavo G. In vivo imaging of axonal transport in murine motor and sensory neurons. Journal of Neuroscience Methods. 257: 26-33. PMID 26424507 DOI: 10.1016/J.Jneumeth.2015.09.018 |
0.578 |
|
2015 |
Joyce PI, Fratta P, Landman AS, McGoldrick P, Wackerhage H, Groves M, Busam BS, Galino J, Corrochano S, Beskina OA, Esapa C, Ryder E, Carter S, Stewart M, Codner G, ... ... Greensmith L, et al. Deficiency of the zinc finger protein ZFP106 causes motor and sensory neurodegeneration. Human Molecular Genetics. PMID 26604141 DOI: 10.1093/Hmg/Ddv471 |
0.44 |
|
2015 |
Rusmini P, Crippa V, Cristofani R, Rinaldi C, Cicardi ME, Galbiati M, Carra S, Bilal M, Greensmith L, Poletti A. The Role of the Protein Quality Control System in SBMA. Journal of Molecular Neuroscience : Mn. PMID 26572535 DOI: 10.1007/S12031-015-0675-6 |
0.346 |
|
2015 |
Gibbs KL, Greensmith L, Schiavo G. Regulation of Axonal Transport by Protein Kinases. Trends in Biochemical Sciences. 40: 597-610. PMID 26410600 DOI: 10.1016/J.Tibs.2015.08.003 |
0.56 |
|
2015 |
Pennuto M, Greensmith L, Pradat PF, Sorarù G. 210th ENMC International Workshop: Research and clinical management of patients with spinal and bulbar muscular atrophy, 27-29 March, 2015, Naarden, The Netherlands. Neuromuscular Disorders : Nmd. 25: 802-12. PMID 26206601 DOI: 10.1016/J.Nmd.2015.06.462 |
0.301 |
|
2015 |
Martin NR, Passey SL, Player DJ, Mudera V, Baar K, Greensmith L, Lewis MP. Neuromuscular Junction Formation in Tissue-Engineered Skeletal Muscle Augments Contractile Function and Improves Cytoskeletal Organization. Tissue Engineering. Part A. 21: 2595-604. PMID 26166548 DOI: 10.1089/Ten.Tea.2015.0146 |
0.402 |
|
2015 |
Mielcarek M, Toczek M, Smeets CJ, Franklin SA, Bondulich MK, Jolinon N, Muller T, Ahmed M, Dick JR, Piotrowska I, Greensmith L, Smolenski RT, Bates GP. HDAC4-myogenin axis as an important marker of HD-related skeletal muscle atrophy. Plos Genetics. 11: e1005021. PMID 25748626 DOI: 10.1371/Journal.Pgen.1005021 |
0.393 |
|
2015 |
Joyce PI, Mcgoldrick P, Saccon RA, Weber W, Fratta P, West SJ, Zhu N, Carter S, Phatak V, Stewart M, Simon M, Kumar S, Heise I, Bros-Facer V, Dick J, ... ... Greensmith L, et al. A novel SOD1-ALS mutation separates central and peripheral effects of mutant SOD1 toxicity. Human Molecular Genetics. 24: 1883-97. PMID 25468678 DOI: 10.1093/Hmg/Ddu605 |
0.427 |
|
2015 |
Carroll J, Page TK, Chiang SC, Kalmar B, Bode D, Greensmith L, Mckinnon PJ, Thorpe JR, Hafezparast M, El-Khamisy SF. Expression of a pathogenic mutation of SOD1 sensitizes aprataxin-deficient cells and mice to oxidative stress and triggers hallmarks of premature ageing. Human Molecular Genetics. 24: 828-40. PMID 25274775 DOI: 10.1093/Hmg/Ddu500 |
0.332 |
|
2015 |
Lu CH, Petzold A, Topping J, Allen K, Macdonald-Wallis C, Clarke J, Pearce N, Kuhle J, Giovannoni G, Fratta P, Sidle K, Fish M, Orrell R, Howard R, Greensmith L, et al. Plasma neurofilament heavy chain levels and disease progression in amyotrophic lateral sclerosis: insights from a longitudinal study. Journal of Neurology, Neurosurgery, and Psychiatry. 86: 565-73. PMID 25009280 DOI: 10.1136/Jnnp-2014-307672 |
0.311 |
|
2015 |
Phadke R, Rossor A, Benoy V, Kalmar B, King R, Greensmith L, Bosch L, Reilly M, Houlden H. Neuropathological findings from a human post mortem case of distal hereditary motor neuropathy (dHMN) due to p.Ser135Phe HSPB1 mutation and transgenic mice with mutant or wild-type HSP27 overexpression Neuromuscular Disorders. 25. DOI: 10.1016/J.Nmd.2015.06.348 |
0.365 |
|
2014 |
Bercsenyi K, Schmieg N, Bryson JB, Wallace M, Caccin P, Golding M, Zanotti G, Greensmith L, Nischt R, Schiavo G. Tetanus toxin entry. Nidogens are therapeutic targets for the prevention of tetanus. Science (New York, N.Y.). 346: 1118-23. PMID 25430769 DOI: 10.1126/Science.1258138 |
0.531 |
|
2014 |
Corrochano S, Männikkö R, Joyce PI, McGoldrick P, Wettstein J, Lassi G, Raja Rayan DL, Blanco G, Quinn C, Liavas A, Lionikas A, Amior N, Dick J, Healy EG, Stewart M, ... ... Greensmith L, et al. Novel mutations in human and mouse SCN4A implicate AMPK in myotonia and periodic paralysis. Brain : a Journal of Neurology. 137: 3171-85. PMID 25348630 DOI: 10.1093/Brain/Awu292 |
0.33 |
|
2014 |
Petchey LK, Risebro CA, Vieira JM, Roberts T, Bryson JB, Greensmith L, Lythgoe MF, Riley PR. Loss of Prox1 in striated muscle causes slow to fast skeletal muscle fiber conversion and dilated cardiomyopathy. Proceedings of the National Academy of Sciences of the United States of America. 111: 9515-20. PMID 24938781 DOI: 10.1073/Pnas.1406191111 |
0.324 |
|
2014 |
Montague K, Malik B, Gray AL, La Spada AR, Hanna MG, Szabadkai G, Greensmith L. Endoplasmic reticulum stress in spinal and bulbar muscular atrophy: a potential target for therapy. Brain : a Journal of Neurology. 137: 1894-906. PMID 24898351 DOI: 10.1093/Brain/Awu114 |
0.394 |
|
2014 |
Parfitt DA, Aguila M, McCulley CH, Bevilacqua D, Mendes HF, Athanasiou D, Novoselov SS, Kanuga N, Munro PM, Coffey PJ, Kalmar B, Greensmith L, Cheetham ME. The heat-shock response co-inducer arimoclomol protects against retinal degeneration in rhodopsin retinitis pigmentosa. Cell Death & Disease. 5: e1236. PMID 24853414 DOI: 10.1038/Cddis.2014.214 |
0.312 |
|
2014 |
Bryson JB, Machado CB, Crossley M, Stevenson D, Bros-Facer V, Burrone J, Greensmith L, Lieberam I. Optical control of muscle function by transplantation of stem cell-derived motor neurons in mice. Science (New York, N.Y.). 344: 94-7. PMID 24700859 DOI: 10.1126/Science.1248523 |
0.412 |
|
2014 |
Bros-Facer V, Krull D, Taylor A, Dick JR, Bates SA, Cleveland MS, Prinjha RK, Greensmith L. Treatment with an antibody directed against Nogo-A delays disease progression in the SOD1G93A mouse model of Amyotrophic lateral sclerosis. Human Molecular Genetics. 23: 4187-200. PMID 24667415 DOI: 10.1093/Hmg/Ddu136 |
0.439 |
|
2014 |
Ricketts T, McGoldrick P, Fratta P, de Oliveira HM, Kent R, Phatak V, Brandner S, Blanco G, Greensmith L, Acevedo-Arozena A, Fisher EM. A nonsense mutation in mouse Tardbp affects TDP43 alternative splicing activity and causes limb-clasping and body tone defects. Plos One. 9: e85962. PMID 24465814 DOI: 10.1371/Journal.Pone.0085962 |
0.378 |
|
2014 |
Kalmar B, Lu CH, Greensmith L. The role of heat shock proteins in Amyotrophic Lateral Sclerosis: The therapeutic potential of Arimoclomol. Pharmacology & Therapeutics. 141: 40-54. PMID 23978556 DOI: 10.1016/J.Pharmthera.2013.08.003 |
0.387 |
|
2014 |
Lu C, Petzold A, Topping J, Kalmar B, Dick J, Orrell R, Malaspina A, Greensmith L. Plasma neurofilaments as a biomarker of disease progression in ALS: insights from longitudinal studies in mice and men F1000research. 5. DOI: 10.7490/F1000Research.1094914.1 |
0.308 |
|
2014 |
Mielcarek M, Rattray I, Osborne G, Jolinon N, Dick J, Bondulich M, Franklin S, Ahmed M, Benjamin A, Goodwin D, Lazell H, Chang X, Lehar A, Wood T, Munoz-Sanjuan I, ... ... Greensmith L, et al. M09 Myostatin Inhibition as a Novel Approach to Targeting Muscle Pathology in HD Journal of Neurology, Neurosurgery & Psychiatry. 85: A97-A97. DOI: 10.1136/Jnnp-2014-309032.281 |
0.375 |
|
2014 |
Devine H, Malik B, Hanna M, Greensmith L. P55 Are axonal transport deficits present in a novel mouse model of spinal and bulbar muscular atrophy? Neuromuscular Disorders. 24: S21-S22. DOI: 10.1016/S0960-8966(14)70071-9 |
0.348 |
|
2014 |
Rossor AM, d'Ydewalle C, Wooley J, Harms M, Reilly MM, Greensmith L, Sumner C, Houlden H. P54 A dominant negative mutation in FBXO38 is a cause of distal hereditary motor neuropathy (dHMN) Neuromuscular Disorders. 24. DOI: 10.1016/S0960-8966(14)70070-7 |
0.344 |
|
2014 |
Kalmar B, Kolaszynska AK, Rossor A, Pandraud A, Reilly M, Greensmith L. P49 Mitochondrial abnormalities and increased oxidative stress in HSBP1iinduced distal hereditary motor neuropathies Neuromuscular Disorders. 24: S20. DOI: 10.1016/S0960-8966(14)70065-3 |
0.303 |
|
2013 |
Sumner CJ, d'Ydewalle C, Wooley J, Fawcett KA, Hernandez D, Gardiner AR, Kalmar B, Baloh RH, Gonzalez M, Züchner S, Stanescu HC, Kleta R, Mankodi A, Cornblath DR, Boylan KB, ... ... Greensmith L, et al. A dominant mutation in FBXO38 causes distal spinal muscular atrophy with calf predominance. American Journal of Human Genetics. 93: 976-83. PMID 24207122 DOI: 10.1016/J.Ajhg.2013.10.006 |
0.428 |
|
2013 |
Schiavo G, Greensmith L, Hafezparast M, Fisher EM. Cytoplasmic dynein heavy chain: the servant of many masters. Trends in Neurosciences. 36: 641-51. PMID 24035135 DOI: 10.1016/J.Tins.2013.08.001 |
0.564 |
|
2013 |
Novoselov SS, Mustill WJ, Gray AL, Dick JR, Kanuga N, Kalmar B, Greensmith L, Cheetham ME. Molecular Chaperone Mediated Late-Stage Neuroprotection in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis Plos One. 8. PMID 24023695 DOI: 10.1371/Journal.Pone.0073944 |
0.454 |
|
2013 |
Oates EC, Rossor AM, Hafezparast M, Gonzalez M, Speziani F, MacArthur DG, Lek M, Cottenie E, Scoto M, Foley AR, Hurles M, Houlden H, Greensmith L, Auer-Grumbach M, Pieber TR, et al. Mutations in BICD2 cause dominant congenital spinal muscular atrophy and hereditary spastic paraplegia. American Journal of Human Genetics. 92: 965-73. PMID 23664120 DOI: 10.1016/J.Ajhg.2013.04.018 |
0.42 |
|
2013 |
McGoldrick P, Joyce PI, Fisher EM, Greensmith L. Rodent models of amyotrophic lateral sclerosis. Biochimica Et Biophysica Acta. 1832: 1421-36. PMID 23524377 DOI: 10.1016/J.Bbadis.2013.03.012 |
0.393 |
|
2013 |
Malik B, Nirmalananthan N, Gray AL, La Spada AR, Hanna MG, Greensmith L. Co-induction of the heat shock response ameliorates disease progression in a mouse model of human spinal and bulbar muscular atrophy: implications for therapy. Brain : a Journal of Neurology. 136: 926-43. PMID 23393146 DOI: 10.1093/Brain/Aws343 |
0.462 |
|
2013 |
Fratta P, Malik B, Gray A, La Spada AR, Hanna MG, Fisher EM, Greensmith L. FUS is not dysregulated by the spinal bulbar muscular atrophy androgen receptor polyglutamine repeat expansion. Neurobiology of Aging. 34: 1516.e17-9. PMID 23062703 DOI: 10.1016/J.Neurobiolaging.2012.09.008 |
0.418 |
|
2013 |
Mitchell JC, McGoldrick P, Vance C, Hortobagyi T, Sreedharan J, Rogelj B, Tudor EL, Smith BN, Klasen C, Miller CC, Cooper JD, Greensmith L, Shaw CE. Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion. Acta Neuropathologica. 125: 273-88. PMID 22961620 DOI: 10.1007/S00401-012-1043-Z |
0.46 |
|
2013 |
Oates E, Rosser A, Hafezparast M, Lek M, Scoto M, Greensmith L, Auer-Grumbach M, Schule R, Herrmann D, Clarke N, MacArthur D, Züchner S, Muntoni F, Reilly M, North K. O.10 Mutations in a new dynein/dynactin adaptor gene cause Dominant Congenital Spinal Muscular Atrophy (DCSMA) and Hereditary Spastic Paraplegia (HSP) Neuromuscular Disorders. 23: 798. DOI: 10.1016/J.Nmd.2013.06.560 |
0.425 |
|
2012 |
Kalmar B, Greensmith L. In Vivo Assessment of Mouse Hindlimb Muscle Force, Contractile, and Fatigue Characteristics, and Motor Unit Number. Current Protocols in Mouse Biology. 2: 89-101. PMID 26069007 DOI: 10.1002/9780470942390.Mo110155 |
0.371 |
|
2012 |
Lu CH, Petzold A, Kalmar B, Dick J, Malaspina A, Greensmith L. Plasma neurofilament heavy chain levels correlate to markers of late stage disease progression and treatment response in SOD1(G93A) mice that model ALS. Plos One. 7: e40998. PMID 22815892 DOI: 10.1371/Journal.Pone.0040998 |
0.397 |
|
2012 |
Rossor AM, Davidson GL, Blake J, Polke JM, Murphy SM, Houlden H, Innes A, Kalmar B, Greensmith L, Reilly MM. A novel p.Glu175X premature stop mutation in the C-terminal end of HSP27 is a cause of CMT2. Journal of the Peripheral Nervous System : Jpns. 17: 201-5. PMID 22734906 DOI: 10.1111/J.1529-8027.2012.00400.X |
0.384 |
|
2012 |
Bryson JB, Hobbs C, Parsons MJ, Bosch KD, Pandraud A, Walsh FS, Doherty P, Greensmith L. Amyloid precursor protein (APP) contributes to pathology in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis. Human Molecular Genetics. 21: 3871-82. PMID 22678056 DOI: 10.1093/Hmg/Dds215 |
0.435 |
|
2012 |
Kalmar B, Edet-Amana E, Greensmith L. Treatment with a coinducer of the heat shock response delays muscle denervation in the SOD1-G93A mouse model of amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 13: 378-92. PMID 22591194 DOI: 10.3109/17482968.2012.660953 |
0.374 |
|
2012 |
Wade A, Thomas C, Kalmar B, Terenzio M, Garin J, Greensmith L, Schiavo G. Activated leukocyte cell adhesion molecule modulates neurotrophin signaling. Journal of Neurochemistry. 121: 575-86. PMID 22243278 DOI: 10.1111/J.1471-4159.2012.07658.X |
0.556 |
|
2012 |
Smith AS, Passey S, Greensmith L, Mudera V, Lewis MP. Characterization and optimization of a simple, repeatable system for the long term in vitro culture of aligned myotubes in 3D. Journal of Cellular Biochemistry. 113: 1044-53. PMID 22065378 DOI: 10.1002/Jcb.23437 |
0.301 |
|
2012 |
Rossor AM, Kalmar B, Greensmith L, Reilly MM. The distal hereditary motor neuropathies. Journal of Neurology, Neurosurgery, and Psychiatry. 83: 6-14. PMID 22028385 DOI: 10.1136/Jnnp-2011-300952 |
0.419 |
|
2012 |
Rossor A, Kalmar B, Gray A, Mustill W, Schiavo G, Cheetham ME, Reilly MM, Greensmith L, Novoselov S. 167 An in-vitro study of distal hereditary motor neuropathy due to homozygous HSJ1 mutations Journal of Neurology, Neurosurgery & Psychiatry. 83: e1.123-e1. DOI: 10.1136/Jnnp-2011-301993.209 |
0.377 |
|
2012 |
Miller A, Ahmed M, Hanna MG, Greensmith L. 098 Developing new therapeutic strategies for inclusion body myositis Journal of Neurology, Neurosurgery & Psychiatry. 83: e1.47-e1. DOI: 10.1136/Jnnp-2011-301993.140 |
0.336 |
|
2011 |
Boërio D, Greensmith L, Bostock H. A model of mouse motor nerve excitability and the effects of polarizing currents Journal of the Peripheral Nervous System. 16: 322-333. PMID 22176147 DOI: 10.1111/J.1529-8027.2011.00364.X |
0.357 |
|
2011 |
Acevedo-Arozena A, Kalmar B, Essa S, Ricketts T, Joyce P, Kent R, Rowe C, Parker A, Gray A, Hafezparast M, Thorpe JR, Greensmith L, Fisher EM. A comprehensive assessment of the SOD1G93A low-copy transgenic mouse, which models human amyotrophic lateral sclerosis. Disease Models & Mechanisms. 4: 686-700. PMID 21540242 DOI: 10.1242/Dmm.007237 |
0.432 |
|
2011 |
Banks GT, Haas MA, Line S, Shepherd HL, Alqatari M, Stewart S, Rishal I, Philpott A, Kalmar B, Kuta A, Groves M, Parkinson N, Acevedo-Arozena A, Brandner S, Bannerman D, ... Greensmith L, et al. Behavioral and other phenotypes in a cytoplasmic Dynein light intermediate chain 1 mutant mouse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 5483-94. PMID 21471385 DOI: 10.1523/Jneurosci.5244-10.2011 |
0.338 |
|
2011 |
Malik B, Nirmalananthan N, Bilsland LG, La Spada AR, Hanna MG, Schiavo G, Gallo JM, Greensmith L. Absence of disturbed axonal transport in spinal and bulbar muscular atrophy. Human Molecular Genetics. 20: 1776-86. PMID 21317158 DOI: 10.1093/Hmg/Ddr061 |
0.609 |
|
2011 |
Joyce P, Fratta P, Phatak V, McGoldrick P, Greensmith L, Fisher EMC, Acevedo-Arozena A. O18 A new mouse model of ALS carrying a point mutation in the mouse Sod1 gene Neuromuscular Disorders. 21. DOI: 10.1016/S0960-8966(11)70019-0 |
0.309 |
|
2011 |
Innes A, Kalmar B, Houlden H, Reilly M, Greensmith L. O08 Characterisation of novel mutations within heat shock protein 27 causing motor axonopathies Neuromuscular Disorders. 21: S3. DOI: 10.1016/S0960-8966(11)70009-8 |
0.33 |
|
2011 |
McGoldrick P, Dick J, Ricketts T, Joyce P, Fratta P, Acevedo-Arozena A, Fisher E, Greensmith L. P16 Investigating novel mutant mouse models of motor neuron disease Neuromuscular Disorders. 21: S11. DOI: 10.1016/S0960-8966(10)70047-X |
0.404 |
|
2010 |
Bilsland LG, Sahai E, Kelly G, Golding M, Greensmith L, Schiavo G. Deficits in axonal transport precede ALS symptoms in vivo. Proceedings of the National Academy of Sciences of the United States of America. 107: 20523-8. PMID 21059924 DOI: 10.1073/Pnas.1006869107 |
0.605 |
|
2010 |
El-Kadi AM, Bros-Facer V, Deng W, Philpott A, Stoddart E, Banks G, Jackson GS, Fisher EM, Duchen MR, Greensmith L, Moore AL, Hafezparast M. The legs at odd angles (Loa) mutation in cytoplasmic dynein ameliorates mitochondrial function in SOD1G93A mouse model for motor neuron disease. The Journal of Biological Chemistry. 285: 18627-39. PMID 20382740 DOI: 10.1074/Jbc.M110.129320 |
0.42 |
|
2010 |
Stevens JC, Chia R, Hendriks WT, Bros-Facer V, van Minnen J, Martin JE, Jackson GS, Greensmith L, Schiavo G, Fisher EM. Modification of superoxide dismutase 1 (SOD1) properties by a GFP tag--implications for research into amyotrophic lateral sclerosis (ALS). Plos One. 5: e9541. PMID 20221404 DOI: 10.1371/Journal.Pone.0009541 |
0.542 |
|
2010 |
Ludolph AC, Bendotti C, Blaugrund E, Chio A, Greensmith L, Loeffler JP, Mead R, Niessen HG, Petri S, Pradat PF, Robberecht W, Ruegg M, Schwalenstöcker B, Stiller D, van den Berg L, et al. Guidelines for preclinical animal research in ALS/MND: A consensus meeting. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 11: 38-45. PMID 20184514 DOI: 10.3109/17482960903545334 |
0.301 |
|
2010 |
Boërio D, Kalmar B, Greensmith L, Bostock H. Excitability properties of mouse motor axons in the mutant SOD1 G93A model of amyotrophic lateral sclerosis Muscle and Nerve. 41: 774-784. PMID 20095022 DOI: 10.1002/Mus.21579 |
0.424 |
|
2010 |
Lu C, Malaspina A, Orrell R, Kalmar B, Petzold A, Greensmith L. PONM06 Plasma neurofilament heavy chain levels as a disease biomarker in the SOD1 mouse model of amyotrophic lateral sclerosis Journal of Neurology, Neurosurgery & Psychiatry. 81: e62-e62. DOI: 10.1136/Jnnp.2010.226340.179 |
0.34 |
|
2010 |
Boerio-Gueguen D, Malik B, Greensmith L, Bostock H. P7-23 Multiple measures of axonal excitability in a mouse model of Kennedy disease Clinical Neurophysiology. 121: S146. DOI: 10.1016/S1388-2457(10)60599-8 |
0.406 |
|
2010 |
Innes A, Kalmar B, Houlden H, Reilly M, Greensmith L. P62 Characterisation of novel mutations within HSP27 causing Charcot–Marie–Tooth disease 2F and distal hereditary motor neuropathy II Neuromuscular Disorders. 20: S21-S22. DOI: 10.1016/S0960-8966(10)70077-8 |
0.341 |
|
2009 |
Banks GT, Bros-Facer V, Williams HP, Chia R, Achilli F, Bryson JB, Greensmith L, Fisher EM. Mutant glycyl-tRNA synthetase (Gars) ameliorates SOD1(G93A) motor neuron degeneration phenotype but has little affect on Loa dynein heavy chain mutant mice. Plos One. 4: e6218. PMID 19593442 DOI: 10.1371/Journal.Pone.0006218 |
0.431 |
|
2009 |
Mackenzie FE, Romero R, Williams D, Gillingwater T, Hilton H, Dick J, Riddoch-Contreras J, Wong F, Ireson L, Powles-Glover N, Riley G, Underhill P, Hough T, Arkell R, Greensmith L, et al. Upregulation of PKD1L2 provokes a complex neuromuscular disease in the mouse Human Molecular Genetics. 18: 3553-3566. PMID 19578180 DOI: 10.1093/Hmg/Ddp304 |
0.377 |
|
2009 |
Achilli F, Bros-Facer V, Williams HP, Banks GT, AlQatari M, Chia R, Tucci V, Groves M, Nickols CD, Seburn KL, Kendall R, Cader MZ, Talbot K, van Minnen J, Burgess RW, ... ... Greensmith L, et al. An ENU-induced mutation in mouse glycyl-tRNA synthetase (GARS) causes peripheral sensory and motor phenotypes creating a model of Charcot-Marie-Tooth type 2D peripheral neuropathy. Disease Models & Mechanisms. 2: 359-73. PMID 19470612 DOI: 10.1242/Dmm.002527 |
0.424 |
|
2009 |
Boërio D, Greensmith L, Bostock H. Excitability properties of motor axons in the maturing mouse Journal of the Peripheral Nervous System. 14: 45-53. PMID 19335539 DOI: 10.1111/J.1529-8027.2009.00205.X |
0.372 |
|
2009 |
Kalmar B, Greensmith L. Activation of the heat shock response in a primary cellular model of motoneuron neurodegeneration-evidence for neuroprotective and neurotoxic effects. Cellular & Molecular Biology Letters. 14: 319-35. PMID 19183864 DOI: 10.2478/S11658-009-0002-8 |
0.314 |
|
2009 |
Riddoch-Contreras J, Yang SY, Dick JR, Goldspink G, Orrell RW, Greensmith L. Mechano-growth factor, an IGF-I splice variant, rescues motoneurons and improves muscle function in SOD1(G93A) mice. Experimental Neurology. 215: 281-9. PMID 19038252 DOI: 10.1016/J.Expneurol.2008.10.014 |
0.388 |
|
2008 |
Bilsland LG, Nirmalananthan N, Yip J, Greensmith L, Duchen MR. Expression of mutant SOD1 in astrocytes induces functional deficits in motoneuron mitochondria. Journal of Neurochemistry. 107: 1271-83. PMID 18808448 DOI: 10.1111/J.1471-4159.2008.05699.X |
0.341 |
|
2008 |
Bilsland LG, Greensmith L. The endocannabinoid system in amyotrophic lateral sclerosis. Current Pharmaceutical Design. 14: 2306-16. PMID 18781981 DOI: 10.2174/138161208785740081 |
0.374 |
|
2008 |
Kalmar B, Novoselov S, Gray A, Cheetham ME, Margulis B, Greensmith L. Late stage treatment with arimoclomol delays disease progression and prevents protein aggregation in the SOD1 mouse model of ALS. Journal of Neurochemistry. 107: 339-50. PMID 18673445 DOI: 10.1111/J.1471-4159.2008.05595.X |
0.386 |
|
2008 |
Ateh DD, Hussain IK, Mustafa AH, Price KM, Gulati R, Nickols CD, Bird MM, Greensmith L, Hafezparast M, Fisher EM, Baker CS, Martin JE. Dynein-dynactin complex subunits are differentially localized in brain and spinal cord, with selective involvement in pathological features of neurodegenerative disease. Neuropathology and Applied Neurobiology. 34: 88-94. PMID 18086204 DOI: 10.1111/J.1365-2990.2007.00924.X |
0.352 |
|
2008 |
Boerio D, Dick J, Bostock H, Greensmith L. MO13 Excitability properties of motor axons in the SOD1 mouse model of ALS Clinical Neurophysiology. 119: S9. DOI: 10.1016/S1388-2457(08)60037-1 |
0.382 |
|
2006 |
Bilsland LG, Dick JR, Pryce G, Petrosino S, Di Marzo V, Baker D, Greensmith L. Increasing cannabinoid levels by pharmacological and genetic manipulation delay disease progression in SOD1 mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1003-5. PMID 16571781 DOI: 10.1096/Fj.05-4743Fje |
0.381 |
|
2005 |
Kalmar B, Kieran D, Greensmith L. Molecular chaperones as therapeutic targets in amyotrophic lateral sclerosis. Biochemical Society Transactions. 33: 551-2. PMID 16042542 DOI: 10.1042/Bst0330551 |
0.345 |
|
2005 |
Achilli F, Boyle S, Kieran D, Chia R, Hafezparast M, Martin JE, Schiavo G, Greensmith L, Bickmore W, Fisher EM. The SOD1 transgene in the G93A mouse model of amyotrophic lateral sclerosis lies on distal mouse chromosome 12. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 6: 111-4. PMID 16036435 DOI: 10.1080/14660820510035351 |
0.521 |
|
2005 |
Kieran D, Hafezparast M, Bohnert S, Dick JR, Martin J, Schiavo G, Fisher EM, Greensmith L. A mutation in dynein rescues axonal transport defects and extends the life span of ALS mice. The Journal of Cell Biology. 169: 561-7. PMID 15911875 DOI: 10.1083/Jcb.200501085 |
0.606 |
|
2005 |
Ralph GS, Radcliffe PA, Day DM, Carthy JM, Leroux MA, Lee DC, Wong LF, Bilsland LG, Greensmith L, Kingsman SM, Mitrophanous KA, Mazarakis ND, Azzouz M. Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model. Nature Medicine. 11: 429-33. PMID 15768029 DOI: 10.1038/Nm1205 |
0.439 |
|
2005 |
Sharp PS, Dick JR, Greensmith L. The effect of peripheral nerve injury on disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis. Neuroscience. 130: 897-910. PMID 15652988 DOI: 10.1016/J.Neuroscience.2004.09.069 |
0.422 |
|
2004 |
Kieran D, Greensmith L. Inhibition of calpains, by treatment with leupeptin, improves motoneuron survival and muscle function in models of motoneuron degeneration. Neuroscience. 125: 427-39. PMID 15062985 DOI: 10.1016/J.Neuroscience.2004.01.046 |
0.348 |
|
2004 |
Kieran D, Kalmar B, Dick JR, Riddoch-Contreras J, Burnstock G, Greensmith L. Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice. Nature Medicine. 10: 402-5. PMID 15034571 DOI: 10.1038/Nm1021 |
0.431 |
|
2004 |
Dekkers J, Bayley P, Dick JR, Schwaller B, Berchtold MW, Greensmith L. Over-expression of parvalbumin in transgenic mice rescues motoneurons from injury-induced cell death. Neuroscience. 123: 459-66. PMID 14698753 DOI: 10.1016/J.Neuroscience.2003.07.013 |
0.391 |
|
2003 |
Kalmar B, Greensmith L, Malcangio M, McMahon SB, Csermely P, Burnstock G. The effect of treatment with BRX-220, a co-inducer of heat shock proteins, on sensory fibers of the rat following peripheral nerve injury. Experimental Neurology. 184: 636-47. PMID 14769355 DOI: 10.1016/S0014-4886(03)00343-1 |
0.339 |
|
2003 |
Sharp PS, Dekkers J, Dick JR, Greensmith L. Manipulating transmitter release at the neuromuscular junction of neonatal rats alters the expression of ChAT and GAP-43 in motoneurons. Brain Research. Developmental Brain Research. 146: 29-38. PMID 14643009 DOI: 10.1016/J.Devbrainres.2003.09.005 |
0.322 |
|
2002 |
Dekkers J, Greensmith L, Navarrete R. Changes in the expression of parvalbumin immunoreactivity in the lumbar spinal cord of the rat following neonatal nerve injury Developmental Neuroscience. 24: 283-293. PMID 12457066 DOI: 10.1159/000066742 |
0.312 |
|
2002 |
Kalmar B, Burnstock G, Vrbová G, Urbanics R, Csermely P, Greensmith L. Upregulation of heat shock proteins rescues motoneurones from axotomy-induced cell death in neonatal rats. Experimental Neurology. 176: 87-97. PMID 12093085 DOI: 10.1006/Exnr.2002.7945 |
0.371 |
|
2002 |
Kalmár B, Burnstock G, Vrbová G, Greensmith L. The effect of neonatal nerve injury on the expression of heat shock proteins in developing rat motoneurones. Journal of Neurotrauma. 19: 667-79. PMID 12042100 DOI: 10.1089/089771502753754127 |
0.325 |
|
2001 |
Dekkers J, Waters J, Vrbová G, Greensmith L. Treatment of the neuromuscular junction with 4-aminopyridine results in improved reinnervation following nerve injury in neonatal rats Neuroscience. 103: 267-274. PMID 11311807 DOI: 10.1016/S0306-4522(00)00541-8 |
0.321 |
|
2001 |
White C, Greensmith L, Vrbova G. Inducing Excessive Axonal Growth Results in the Death of Otherwise Healthy Adult Rat Motor Neurones Physiotherapy. 87: 98. DOI: 10.1016/S0031-9406(05)60468-3 |
0.357 |
|
2000 |
Greensmith L, Ng P, Mohaghegh P, Vrbová G. Reducing transmitter release from nerve terminals influences motoneuron survival in developing rats. Neuroscience. 97: 357-62. PMID 10799767 DOI: 10.1016/S0306-4522(00)00072-5 |
0.344 |
|
2000 |
White CM, Greensmith L, Vrbová G. Repeated stimuli for axonal growth causes motoneuron death in adult rats: the effect of botulinum toxin followed by partial denervation. Neuroscience. 95: 1101-9. PMID 10682717 DOI: 10.1016/S0306-4522(99)00512-6 |
0.379 |
|
1999 |
Wong KC, Meyer T, Harding DI, Dick JR, Vrbová G, Greensmith L. Integrins at the neuromuscular junction are important for motoneuron survival. The European Journal of Neuroscience. 11: 3287-92. PMID 10510192 DOI: 10.1046/J.1460-9568.1999.00749.X |
0.349 |
|
1999 |
Harding DI, Greensmith L, Vrbová G. Stabilizing neuromuscular contacts reduces motoneuron death caused by paralysis of muscles in neonatal rats. Neuroscience. 93: 1141-6. PMID 10473278 DOI: 10.1016/S0306-4522(99)00184-0 |
0.351 |
|
1999 |
Harding DI, Greensmith L, Mason M, Anderson PN, Vrbová G. Overexpression of GAP-43 induces prolonged sprouting and causes death of adult motoneurons. The European Journal of Neuroscience. 11: 2237-42. PMID 10383612 DOI: 10.1046/J.1460-9568.1999.00640.X |
0.39 |
|
1998 |
Sanusi J, Greensmith L, Lowrie MB, Vrbová G. Motoneurones that innervate the rat soleus muscle mature later than those to the tibialis anterior and extensor digitorum longus muscles. Developmental Neuroscience. 20: 546-51. PMID 9858844 DOI: 10.1159/000017356 |
0.367 |
|
1998 |
Greensmith L, Harding DI, Meyer MP, Vrbová G. Mechanical activity is necessary for the elimination of polyneuronal innervation of developing rat soleus muscles. Brain Research. Developmental Brain Research. 110: 131-4. PMID 9733950 DOI: 10.1016/S0165-3806(98)00106-0 |
0.33 |
|
1998 |
Harding DI, Greensmith L, Anderson PN, Vrbová G. Motoneurons innervating partially denervated rat hindlimb muscles remain susceptible to axotomy-induced cell death. Neuroscience. 86: 291-9. PMID 9692762 DOI: 10.1016/S0306-4522(98)00037-2 |
0.365 |
|
1997 |
Greensmith L, Vrbová G. Disturbances of neuromuscular interaction may contribute to muscle weakness in spinal muscular atrophy. Neuromuscular Disorders : Nmd. 7: 369-72. PMID 9327400 DOI: 10.1016/S0960-8966(97)00047-3 |
0.362 |
|
1997 |
Greensmith L, Hind A, Vrbová G. Neonatal paralysis of the rat soleus muscle selectively affects motoneurones from more caudal segments of the spinal cord. Brain Research. Developmental Brain Research. 98: 281-6. PMID 9051271 DOI: 10.1016/S0165-3806(96)00200-3 |
0.347 |
|
1997 |
Harding DI, Greensmith L, Connold AL, Vrbová G. Stabilizing neuromuscular contacts increases motoneuron survival after neonatal nerve injury in rats. Neuroscience. 70: 799-805. PMID 9045089 DOI: 10.1016/S0306-4522(96)83016-8 |
0.379 |
|
1996 |
Greensmith L, Vrbova G. Motoneurone survival: a functional approach. Trends in Neurosciences. 19: 450. PMID 8931265 DOI: 10.1016/S0166-2236(96)20034-7 |
0.354 |
|
1996 |
Greensmith L, Dick J, Emanuel AO, Vrbová G. Induction of transmitter release at the neuromuscular junction prevents motoneuron death after axotomy in neonatal rats. Neuroscience. 71: 213-20. PMID 8834403 DOI: 10.1016/0306-4522(95)00446-7 |
0.348 |
|
1996 |
Dick J, Greensmith L, Vrbova G. Blocking of NMDA receptors during a critical stage of development reduces the effects of nerve injury at birth on muscles and motoneurones. Neuromuscular Disorders : Nmd. 5: 371-82. PMID 7496171 DOI: 10.1016/0960-8966(94)00088-Q |
0.356 |
|
1996 |
Greensmith L, Vrbová G. Possible strategies for treatment of SMA patients: a neurobiologist's view. Neuromuscular Disorders : Nmd. 5: 359-69. PMID 7496170 DOI: 10.1016/0960-8966(94)00090-V |
0.392 |
|
1996 |
Greensmith L, Hind AH, Vrbová G. Transient disruption of nerve-muscle interaction shortly after birth permanently alters the development of the rat soleus muscle Developmental Brain Research. 94: 152-158. DOI: 10.1016/S0165-3806(96)80006-X |
0.332 |
|
1995 |
Kerai B, Greensmith L, Vrbová G, Navarrete R. Effect of transient neonatal muscle paralysis on the growth of soleus motoneurones in the rat. Brain Research. Developmental Brain Research. 85: 89-95. PMID 7781172 DOI: 10.1016/0165-3806(94)00198-9 |
0.316 |
|
1995 |
Greensmith L, Sanusi J, Mentis GZ, Vrbová G. Transient muscle paralysis in neonatal rats renders motoneurons susceptible to N-methyl-d-aspartate-induced neurotoxicity Neuroscience. 64: 109-115. PMID 7708198 DOI: 10.1016/0306-4522(94)00387-K |
0.346 |
|
1994 |
Greensmith L, Mentis GZ, Vrbová G. Blockade of N-methyl-d-aspartate receptors by MK-801 (dizocilpine maleate) rescues motoneurones in developing rats Developmental Brain Research. 81: 162-170. PMID 7813038 DOI: 10.1016/0165-3806(94)90302-6 |
0.35 |
|
1993 |
Mentis GZ, Greensmith L, Vrbová G. Motoneurons destined to die are rescued by blocking n-methyl-d-aspartate receptors by MK-801 Neuroscience. 54: 283-285. PMID 8336825 DOI: 10.1016/0306-4522(93)90253-C |
0.355 |
|
1992 |
Greensmith L, Vrbová G. Alterations of nerve-muscle interaction during postnatal development influence motoneurone survival in rats. Brain Research. Developmental Brain Research. 69: 125-31. PMID 1424084 DOI: 10.1016/0165-3806(92)90129-K |
0.337 |
|
1992 |
Vrbová G, Greensmith L, Sieradzan K. Motor neuron disease model. Nature. 360: 216. PMID 1296614 DOI: 10.1038/360216B0 |
0.37 |
|
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