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David B. Knowles, Ph.D. - Publications

Affiliations: 
2001 University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Organic Chemistry
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4 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Sutherlin DP, Baker S, Bisconte A, Blaney PM, Brown A, Chan BK, Chantry D, Castanedo G, DePledge P, Goldsmith P, Goldstein DM, Hancox T, Kaur J, Knowles D, Kondru R, et al. Potent and selective inhibitors of PI3Kδ: obtaining isoform selectivity from the affinity pocket and tryptophan shelf. Bioorganic & Medicinal Chemistry Letters. 22: 4296-302. PMID 22672799 DOI: 10.1016/J.Bmcl.2012.05.027  0.454
2009 Nissen MS, Kumar GN, Youn B, Knowles DB, Lam KS, Ballinger WJ, Knowles NR, Kang C. Characterization of Solanum tuberosum multicystatin and its structural comparison with other cystatins. The Plant Cell. 21: 861-75. PMID 19304935 DOI: 10.1105/Tpc.108.064717  0.389
2002 Ohkanda J, Knowles DB, Blaskovich MA, Sebti SM, Hamilton AD. Inhibitors of protein farnesyltransferase as novel anticancer agents. Current Topics in Medicinal Chemistry. 2: 303-23. PMID 11944822 DOI: 10.2174/1568026023394281  0.64
1997 Lerner EC, Zhang TT, Knowles DB, Qian Y, Hamilton AD, Sebti SM. Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell lines Oncogene. 15: 1283-1288. PMID 9315095 DOI: 10.1038/Sj.Onc.1201296  0.501
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