| Year |
Citation |
Score |
| 2023 |
Bhat S, El-Kasaby A, Kasture A, Boytsov D, Reichelt JB, Hummel T, Sucic S, Pifl C, Freissmuth M, Sandtner W. A mechanism of uncompetitive inhibition of the serotonin transporter. Elife. 12. PMID 36648438 DOI: 10.7554/eLife.82641 |
0.305 |
|
| 2020 |
Nasrollahi-Shirazi S, Szöllösi D, Yang Q, Muratspahic E, El-Kasaby A, Sucic S, Stockner T, Nanoff C, Freissmuth M. Functional Impact of the G279S Substitution in the Adenosine A-Receptor (AR-G279S), a Mutation Associated with Parkinson's Disease. Molecular Pharmacology. 98: 250-266. PMID 32817461 DOI: 10.1124/Molpharm.120.000003 |
0.335 |
|
| 2020 |
Zhu R, Sandtner W, Ahiable JEA, Newman AH, Freissmuth M, Sitte HH, Hinterdorfer P. Allosterically Linked Binding Sites in Serotonin Transporter Revealed by Single Molecule Force Spectroscopy. Frontiers in Molecular Biosciences. 7: 99. PMID 32656227 DOI: 10.3389/Fmolb.2020.00099 |
0.324 |
|
| 2020 |
Esendir E, Burtscher V, Sandtner W, Freissmuth M. Interrogating the Role of Extracellular Loops 2 and 4 (EL2 and EL4) of the Serotonin Transporter with Antibody Fragments The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03940 |
0.335 |
|
| 2020 |
Zhu R, Gobl J, Holy M, Kudlacek O, Sandtner W, Stockner T, Gruber HJ, Freissmuth M, Hauck Newman A, Sitte HH, Hinterdorfer P. Two Distinct Ligand Binding Sites in Monoamine Transporters Monitored by Nanopharmacological Force Sensing Biophysical Journal. 118: 618a-619a. DOI: 10.1016/J.Bpj.2019.11.3337 |
0.333 |
|
| 2019 |
Burtscher V, Schicker K, Freissmuth M, Sandtner W. Kinetic Models of Secondary Active Transporters. International Journal of Molecular Sciences. 20. PMID 31661895 DOI: 10.3390/Ijms20215365 |
0.374 |
|
| 2019 |
Erdem FA, Ilic M, Koppensteiner P, Gołacki J, Lubec G, Freissmuth M, Sandtner W. A comparison of the transport kinetics of glycine transporter 1 and glycine transporter 2. The Journal of General Physiology. PMID 31270129 DOI: 10.1085/Jgp.201912318 |
0.399 |
|
| 2019 |
Bhat S, Newman AH, Freissmuth M. How to rescue misfolded SERT, DAT and NET: targeting conformational intermediates with atypical inhibitors and partial releasers. Biochemical Society Transactions. PMID 31064865 DOI: 10.1042/Bst20180512 |
0.425 |
|
| 2019 |
Niello M, Cintulova D, Hellsberg E, Jäntsch K, Holy M, Ayatollahi LH, Cozzi NV, Freissmuth M, Sandtner W, Ecker GF, Mihovilovic MD, Sitte HH. para-Trifluoromethyl-methcathinone is an allosteric modulator of the serotonin transporter. Neuropharmacology. PMID 31028773 DOI: 10.1016/J.Neuropharm.2019.04.021 |
0.378 |
|
| 2019 |
El-Kasaby A, Kasture A, Koban F, Hotka M, Asjad HMM, Kubista H, Freissmuth M, Sucic S. Rescue by 4-phenylbutyrate of several misfolded creatine transporter-1 variants linked to the creatine transporter deficiency syndrome. Neuropharmacology. PMID 30885608 DOI: 10.1016/J.Neuropharm.2019.03.015 |
0.374 |
|
| 2019 |
Kasture AS, Bartel D, Steinkellner T, Sucic S, Hummel T, Freissmuth M. Distinct contribution of axonal and somatodendritic serotonin transporters in drosophila olfaction. Neuropharmacology. PMID 30851308 DOI: 10.1016/J.Neuropharm.2019.03.007 |
0.302 |
|
| 2018 |
Hasenhuetl PS, Bhat S, Freissmuth M, Sandtner W. Functional selectivity and partial efficacy at the monoamine transporters: a unified model of allosteric modulation and amphetamine-induced substrate release. Molecular Pharmacology. PMID 30567955 DOI: 10.1124/Mol.118.114793 |
0.388 |
|
| 2018 |
Kovalchuk V, Samluk Ł, Juraszek B, Jurkiewicz-Trząska D, Sucic S, Freissmuth M, Nałęcz KA. Trafficking of the amino acid transporter B (SLC6A14) to the plasma membrane involves an exclusive interaction with SEC24C for its exit from the endoplasmic reticulum. Biochimica Et Biophysica Acta. Molecular Cell Research. PMID 30445147 DOI: 10.1016/J.Bbamcr.2018.11.005 |
0.373 |
|
| 2018 |
Hamali B, Pichler S, Wischnitzki E, Schicker K, Burger M, Holy M, Jaentsch K, Molin M, Sehr EM, Kudlacek O, Freissmuth M. Identification and characterization of the Fasciola hepatica sodium- and chloride-dependent taurine transporter. Plos Neglected Tropical Diseases. 12: e0006428. PMID 29702654 DOI: 10.1371/Journal.Pntd.0006428 |
0.35 |
|
| 2018 |
Burtscher V, Hotka M, Li Y, Freissmuth M, Sandtner W. A label-free approach to detect ligand binding to cell surface proteins in real time. Elife. 7. PMID 29697048 DOI: 10.7554/Elife.34944 |
0.333 |
|
| 2018 |
Hasenhuetl PS, Bhat S, Mayer FP, Sitte HH, Freissmuth M, Sandtner W. A kinetic account for amphetamine-induced monoamine release. The Journal of General Physiology. PMID 29439119 DOI: 10.1085/Jgp.201711915 |
0.371 |
|
| 2017 |
Asjad HMM, Nasrollahi-Shirazi S, Sucic S, Freissmuth M, Nanoff C. Relax, Cool Down and Scaffold: How to Restore Surface Expression of Folding-Deficient Mutant GPCRs and SLC6 Transporters. International Journal of Molecular Sciences. 18. PMID 29135937 DOI: 10.3390/Ijms18112416 |
0.41 |
|
| 2017 |
Freissmuth M, Stockner T, Sucic S. SLC6 Transporter Folding Diseases and Pharmacochaperoning. Handbook of Experimental Pharmacology. PMID 29086036 DOI: 10.1007/164_2017_71 |
0.374 |
|
| 2017 |
Asjad HMM, Kasture A, El-Kasaby A, Sackel M, Hummel T, Freissmuth M, Sucic S. PHARMACOCHAPERONING IN A DROSOPHILA MODEL SYSTEM RESCUES HUMAN DOPAMINE TRANSPORTER VARIANTS ASSOCIATED WITH INFANTILE/JUVENILE PARKINSONISM. The Journal of Biological Chemistry. PMID 28972153 DOI: 10.1074/Jbc.M117.797092 |
0.353 |
|
| 2017 |
Kasture A, Stockner T, Freissmuth M, Sucic S. An unfolding story: small molecules remedy misfolded monoamine transporters. The International Journal of Biochemistry & Cell Biology. PMID 28890376 DOI: 10.1016/J.Biocel.2017.09.004 |
0.408 |
|
| 2017 |
Bhat S, Hasenhuetl PS, Kasture A, El-Kasaby A, Baumann MH, Blough BE, Sucic S, Sandtner W, Freissmuth M. Conformational state interactions provide clues to the pharmacochaperone potential of serotonin transporter partial substrates. The Journal of Biological Chemistry. PMID 28842491 DOI: 10.1074/Jbc.M117.794081 |
0.407 |
|
| 2017 |
Spork M, Sohail MI, Schmid D, Ecker GF, Freissmuth M, Chiba P, Stockner T. Folding correction of ABC-transporter ABCB1 by pharmacological chaperones: a mechanistic concept. Pharmacology Research & Perspectives. 5: e00325. PMID 28603639 DOI: 10.1002/Prp2.325 |
0.408 |
|
| 2017 |
Kern C, Erdem FA, El-Kasaby A, Sandtner W, Freissmuth M, Sucic S. The N Terminus Specifies the Switch between Transport Modes of the Human Serotonin Transporter. The Journal of Biological Chemistry. 292: 3603-3613. PMID 28104804 DOI: 10.1074/Jbc.M116.771360 |
0.382 |
|
| 2017 |
Li Y, Mayer FP, Hasenhuetl PS, Burtscher V, Schicker K, Sitte HH, Freissmuth M, Sandtner W. Occupancy of the Zinc Binding-site by Transition Metals decreases the Substrate Affinity of the Human Dopamine Transporter by an Allosteric Mechanism. The Journal of Biological Chemistry. PMID 28096460 DOI: 10.1074/Jbc.M116.760140 |
0.351 |
|
| 2016 |
Schaletzki Y, Kromrey ML, Bröderdorf S, Hammer E, Grube M, Hagen P, Sucic S, Freissmuth M, Völker U, Greinacher A, Rauch BH, Kroemer HK, Jedlitschky G. Several adaptor proteins promote intracellular localisation of the transporter MRP4/ABCC4 in platelets and haematopoietic cells. Thrombosis and Haemostasis. 117. PMID 27761583 DOI: 10.1160/Th16-01-0045 |
0.365 |
|
| 2016 |
Hasenhuetl PS, Freissmuth M, Sandtner W. Electrogenic Binding of Intracellular Cations Defines a Kinetic Decision Point in the Transport Cycle of the Human Serotonin Transporter. The Journal of Biological Chemistry. 291: 25864-25876. PMID 27756841 DOI: 10.1074/Jbc.M116.753319 |
0.394 |
|
| 2016 |
Kasture A, El-Kasaby A, Szöllősi D, Asjad HM, Grimm A, Stockner T, Hummel T, Freissmuth M, Sucic S. Functional rescue of a misfolded Drosophila melanogaster dopamine transporter mutant associated with a sleepless phenotype by pharmacological chaperones. The Journal of Biological Chemistry. PMID 27481941 DOI: 10.1074/Jbc.M116.737551 |
0.365 |
|
| 2016 |
Hasenhuetl PS, Freissmuth M, Sitte HH, Schicker K, Li Y, Sandtner W. Dissecting the Catalytic Cycle of the Serotonin Transporter Biophysical Journal. 110: 179a. DOI: 10.1016/J.Bpj.2015.11.999 |
0.422 |
|
| 2016 |
Zhu R, Heilinger A, Newman AH, Freissmuth M, Sitte HH, Hinterdorfer P. Nanopharmacological Force Sensing Reveals Two Ligand Binding Sites in Monoamine Transporters Biophysical Journal. 110: 9a. DOI: 10.1016/J.Bpj.2015.11.104 |
0.348 |
|
| 2015 |
Zhu R, Sinwel D, Hasenhuetl PS, Saha K, Kumar V, Zhang P, Rankl C, Holy M, Sucic S, Kudlacek O, Karner A, Sandtner W, Stockner T, Gruber HJ, Freissmuth M, et al. Nanopharmacological Force Sensing to Reveal Allosteric Coupling in Transporter Binding Sites. Angewandte Chemie (International Ed. in English). PMID 26695726 DOI: 10.1002/Anie.201508755 |
0.327 |
|
| 2015 |
Li Y, Hasenhuetl PS, Schicker K, Sitte HH, Freissmuth M, Sandtner W. Dual Action of Zn2+ on the Transport Cycle of the Dopamine Transporter. The Journal of Biological Chemistry. 290: 31069-76. PMID 26504078 DOI: 10.1074/Jbc.M115.688275 |
0.384 |
|
| 2015 |
Venkatesan S, Saha K, Sohail A, Sandtner W, Freissmuth M, Ecker GF, Sitte HH, Stockner T. Refinement of the Central Steps of Substrate Transport by the Aspartate Transporter GltPh: Elucidating the Role of the Na2 Sodium Binding Site. Plos Computational Biology. 11: e1004551. PMID 26485255 DOI: 10.1371/Journal.Pcbi.1004551 |
0.389 |
|
| 2015 |
Steinkellner T, Montgomery TR, Hofmaier T, Kudlacek O, Yang JW, Rickhag M, Jung G, Lubec G, Gether U, Freissmuth M, Sitte HH. Amphetamine action at the cocaine- and antidepressant-sensitive serotonin transporter is modulated by αCaMKII. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8258-71. PMID 26019340 DOI: 10.1523/Jneurosci.4034-14.2015 |
0.392 |
|
| 2015 |
Hasenhuetl PS, Schicker K, Koenig X, Li Y, Sarker S, Stockner T, Sucic S, Sitte HH, Freissmuth M, Sandtner W. Ligand Selectivity among the Dopamine and Serotonin Transporters Specified by the Forward Binding Reaction. Molecular Pharmacology. 88: 12-8. PMID 25873594 DOI: 10.1124/Mol.115.099036 |
0.72 |
|
| 2015 |
Koban F, El-Kasaby A, Häusler C, Stockner T, Simbrunner BM, Sitte HH, Freissmuth M, Sucic S. A salt bridge linking the first intracellular loop with the C terminus facilitates the folding of the serotonin transporter. The Journal of Biological Chemistry. 290: 13263-78. PMID 25869136 DOI: 10.1074/Jbc.M115.641357 |
0.343 |
|
| 2015 |
Sitte HH, Schütz GJ, Freissmuth M. Cooperativity between individual transporter protomers: new data fuelling old complexes. Journal of Neurochemistry. 133: 163-6. PMID 25772534 DOI: 10.1111/Jnc.13086 |
0.399 |
|
| 2015 |
Sitte HH, Freissmuth M. Amphetamines, new psychoactive drugs and the monoamine transporter cycle. Trends in Pharmacological Sciences. 36: 41-50. PMID 25542076 DOI: 10.1016/J.Tips.2014.11.006 |
0.383 |
|
| 2015 |
Kusek J, Yang Q, Witek M, Gruber CW, Nanoff C, Freissmuth M. Chaperoning of the a1-adenosine receptor by endogenous adenosine-an extension of the retaliatory metabolite concept Molecular Pharmacology. 87: 39-51. PMID 25354767 DOI: 10.1124/Mol.114.094045 |
0.338 |
|
| 2015 |
Schmid D, Koenig X, Bulusu S, Schicker K, Freissmuth M, Sitte HH, Sandtner W. The conservative view: Is it necessary to implant a stent into the dopamine transporter? British Journal of Pharmacology. 172: 4775-4778. PMID 24824446 DOI: 10.1111/Bph.12766 |
0.346 |
|
| 2015 |
Hasenhuetl PS, Freissmuth M, Sitte HH, Sandtner W. A Kinetic Assessment of Ligand Binding to Monoamine-Transporters Biophysical Journal. 108: 463a. DOI: 10.1016/J.Bpj.2014.11.2524 |
0.368 |
|
| 2015 |
Sitte HH, Venkatesan S, Sohail A, Saha K, Jayaraman K, Ecker GF, Freissmuth M, Sandtner W, Stockner T. Transporters in Motion: Combining Computational Approaches and LRET-Measurements Biophysical Journal. 108: 199a. DOI: 10.1016/J.Bpj.2014.11.1101 |
0.38 |
|
| 2014 |
El-Kasaby A, Koban F, Sitte HH, Freissmuth M, Sucic S. A cytosolic relay of heat shock proteins HSP70-1A and HSP90β monitors the folding trajectory of the serotonin transporter. The Journal of Biological Chemistry. 289: 28987-9000. PMID 25202009 DOI: 10.1074/Jbc.M114.595090 |
0.35 |
|
| 2014 |
Michl J, Scharinger C, Zauner M, Kasper S, Freissmuth M, Sitte HH, Ecker GF, Pezawas L. A multivariate approach linking reported side effects of clinical antidepressant and antipsychotic trials to in vitro binding affinities. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 24: 1463-74. PMID 25044049 DOI: 10.1016/J.Euroneuro.2014.06.013 |
0.321 |
|
| 2014 |
Steinkellner T, Mus L, Eisenrauch B, Constantinescu A, Leo D, Konrad L, Rickhag M, Sørensen G, Efimova EV, Kong E, Willeit M, Sotnikova TD, Kudlacek O, Gether U, Freissmuth M, et al. In vivo amphetamine action is contingent on αCaMKII. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2681-93. PMID 24871545 DOI: 10.1038/Npp.2014.124 |
0.362 |
|
| 2014 |
Montgomery TR, Steinkellner T, Sucic S, Koban F, Schüchner S, Ogris E, Sitte HH, Freissmuth M. Axonal targeting of the serotonin transporter in cultured rat dorsal raphe neurons is specified by SEC24C-dependent export from the endoplasmic reticulum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 6344-51. PMID 24790205 DOI: 10.1523/Jneurosci.2991-13.2014 |
0.323 |
|
| 2014 |
Thurner P, Gsandtner I, Kudlacek O, Choquet D, Nanoff C, Freissmuth M, Zezula J. A two-state model for the diffusion of the A2A adenosine receptor in hippocampal neurons: agonist-induced switch to slow mobility is modified by synapse-associated protein 102 (SAP102). The Journal of Biological Chemistry. 289: 9263-74. PMID 24509856 DOI: 10.1074/Jbc.M113.505685 |
0.33 |
|
| 2014 |
Chiba P, Freissmuth M, Stockner T. Defining the blanks--pharmacochaperoning of SLC6 transporters and ABC transporters. Pharmacological Research. 83: 63-73. PMID 24316454 DOI: 10.1016/J.Phrs.2013.11.009 |
0.409 |
|
| 2014 |
Hofmaier T, Luf A, Seddik A, Stockner T, Holy M, Freissmuth M, Ecker GF, Schmid R, Sitte HH, Kudlacek O. Aminorex, a metabolite of the cocaine adulterant levamisole, exerts amphetamine like actions at monoamine transporters. Neurochemistry International. 73: 32-41. PMID 24296074 DOI: 10.1016/J.Neuint.2013.11.010 |
0.338 |
|
| 2014 |
Sandtner W, Schmid D, Schicker K, Gerstbrein K, Koenig X, Mayer FP, Boehm S, Freissmuth M, Sitte HH. A quantitative model of amphetamine action on the 5-HT transporter. British Journal of Pharmacology. 171: 1007-18. PMID 24251585 DOI: 10.1111/Bph.12520 |
0.373 |
|
| 2014 |
Sandtner W, Schmid D, Schicker K, Freissmuth M, Sitte HH. A Quantitative Model of Amphetamine Action on the Serotonin Transporter Biophysical Journal. 106: 365a. DOI: 10.1016/J.Bpj.2013.11.2069 |
0.375 |
|
| 2014 |
Sohail A, Kudlacek O, Daerr M, Stolt-Bergner P, Ecker G, Freissmuth M, Wanner K, Stockner T, Sandtner W, Sitte H. Unfolding the Structure of LeuT Employing Luminescence Resonance Energy Transfer Biophysical Journal. 106: 258a. DOI: 10.1016/J.Bpj.2013.11.1515 |
0.374 |
|
| 2013 |
Bergmayr C, Thurner P, Keuerleber S, Kudlacek O, Nanoff C, Freissmuth M, Gruber CW. Recruitment of a cytoplasmic chaperone relay by the A2A adenosine receptor Journal of Biological Chemistry. 288: 28831-28844. PMID 23965991 DOI: 10.1074/Jbc.M113.464776 |
0.357 |
|
| 2013 |
Stockner T, Montgomery TR, Kudlacek O, Weissensteiner R, Ecker GF, Freissmuth M, Sitte HH. Mutational analysis of the high-affinity zinc binding site validates a refined human dopamine transporter homology model. Plos Computational Biology. 9: e1002909. PMID 23436987 DOI: 10.1371/Journal.Pcbi.1002909 |
0.393 |
|
| 2013 |
Rosenauer R, Luf A, Holy M, Freissmuth M, Schmid R, Sitte HH. A combined approach using transporter-flux assays and mass spectrometry to examine psychostimulant street drugs of unknown content. Acs Chemical Neuroscience. 4: 182-90. PMID 23336057 DOI: 10.1021/Cn3001763 |
0.304 |
|
| 2013 |
Sucic S, Koban F, El-Kasaby A, Kudlacek O, Stockner T, Sitte HH, Freissmuth M. Switching the clientele: a lysine residing in the C terminus of the serotonin transporter specifies its preference for the coat protein complex II component SEC24C. The Journal of Biological Chemistry. 288: 5330-41. PMID 23288844 DOI: 10.1074/Jbc.M112.408237 |
0.413 |
|
| 2012 |
Nanoff C, Freissmuth M. ER-bound steps in the biosynthesis of G protein-coupled receptors. Sub-Cellular Biochemistry. 63: 1-21. PMID 23161130 DOI: 10.1007/978-94-007-4765-4_1 |
0.361 |
|
| 2012 |
Keuerleber S, Thurner P, Gruber CW, Zezula J, Freissmuth M. Reengineering the collision coupling and diffusion mode of the A 2A-adenosine receptor: Palmitoylation in helix 8 relieves confinement Journal of Biological Chemistry. 287: 42104-42118. PMID 23071116 DOI: 10.1074/Jbc.M112.393579 |
0.323 |
|
| 2012 |
Steinkellner T, Yang JW, Montgomery TR, Chen WQ, Winkler MT, Sucic S, Lubec G, Freissmuth M, Elgersma Y, Sitte HH, Kudlacek O. Ca(2+)/calmodulin-dependent protein kinase IIα (αCaMKII) controls the activity of the dopamine transporter: implications for Angelman syndrome. The Journal of Biological Chemistry. 287: 29627-35. PMID 22778257 DOI: 10.1074/Jbc.M112.367219 |
0.368 |
|
| 2012 |
Bulling S, Schicker K, Zhang YW, Steinkellner T, Stockner T, Gruber CW, Boehm S, Freissmuth M, Rudnick G, Sitte HH, Sandtner W. The mechanistic basis for noncompetitive ibogaine inhibition of serotonin and dopamine transporters. The Journal of Biological Chemistry. 287: 18524-34. PMID 22451652 DOI: 10.1074/Jbc.M112.343681 |
0.424 |
|
| 2012 |
Schicker K, Uzelac Z, Gesmonde J, Bulling S, Stockner T, Freissmuth M, Boehm S, Rudnick G, Sitte HH, Sandtner W. Unifying concept of serotonin transporter-associated currents. The Journal of Biological Chemistry. 287: 438-45. PMID 22072712 DOI: 10.1074/Jbc.M111.304261 |
0.345 |
|
| 2012 |
Wildling L, Rankl C, Haselgrübler T, Gruber HJ, Holy M, Newman AH, Zou MF, Zhu R, Freissmuth M, Sitte HH, Hinterdorfer P. Probing binding pocket of serotonin transporter by single molecular force spectroscopy on living cells. The Journal of Biological Chemistry. 287: 105-13. PMID 22033932 DOI: 10.1074/Jbc.M111.304873 |
0.382 |
|
| 2012 |
Thurner P, Keuerleber S, Gsandtner I, Gruber C, Freissmuth M, Zezula J. Restricted collision coupling of the adenosine A2Areceptor is due to its agonist-induced confinement in the membrane Bmc Pharmacology and Toxicology. 13. DOI: 10.1186/2050-6511-13-S1-A81 |
0.344 |
|
| 2012 |
Kusek J, Gruber CW, Nanoff C, Freissmuth M. Pharmacochaperoning of the ER-retained A1 adenosine receptor Bmc Pharmacology and Toxicology. 13: A63. DOI: 10.1186/2050-6511-13-S1-A63 |
0.342 |
|
| 2012 |
Jayaraman K, Sohail A, Freissmuth M, Sitte HH, Stockner T. Identifying forces that stabilize the oligomeric state of bacterial homologs of neurotransmitter transporters Bmc Pharmacology and Toxicology. 13: A59. DOI: 10.1186/2050-6511-13-S1-A59 |
0.345 |
|
| 2012 |
Steinkellner T, Montgomery T, Yang J, Rickhag M, Sucic S, Elgersma Y, Kudlacek O, Freissmuth M, Gether U, Sitte HH. Calmodulin kinase II regulates amphetamine-induced reverse transport in dopamine and serotonin transporters Bmc Pharmacology and Toxicology. 13. DOI: 10.1186/2050-6511-13-S1-A56 |
0.413 |
|
| 2012 |
El-Kasaby A, Koban F, Freissmuth M, Sucic S. How does the carboxyl terminus assist folding and ER export of the serotonin transporter? Bmc Pharmacology and Toxicology. 13: A55. DOI: 10.1186/2050-6511-13-S1-A55 |
0.411 |
|
| 2012 |
Sucic S, Kern C, Sitte HH, Freissmuth M. The N-terminus acts as a lever to support amphetamine-induced substrate efflux by the serotonin transporter Bmc Pharmacology and Toxicology. 13. DOI: 10.1186/2050-6511-13-S1-A54 |
0.363 |
|
| 2012 |
Sohail A, Bulling S, Stolt-Bergner P, Kudlacek O, Ecker GF, Freissmuth M, Stockner T, Sitte HH, Sandtner W. Decrypting structural and functional changes in LeuTAa at atomic level employing LRET Bmc Pharmacology and Toxicology. 13: A53. DOI: 10.1186/2050-6511-13-S1-A53 |
0.336 |
|
| 2012 |
Sandtner W, Schicker K, Freissmuth M, Rudnick G, Sitte HH. A Unifying Concept of Serotonin Transporter Associated Currents Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.3875 |
0.351 |
|
| 2011 |
Geetha N, Mihaly J, Stockenhuber A, Blasi F, Uhrin P, Binder BR, Freissmuth M, Breuss JM. Signal integration and coincidence detection in the mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) cascade: concomitant activation of receptor tyrosine kinases and of LRP-1 leads to sustained ERK phosphorylation via down-regulation of dual specificity phosphatases (DUSP1 and -6). The Journal of Biological Chemistry. 286: 25663-74. PMID 21610072 DOI: 10.1074/Jbc.M111.221903 |
0.318 |
|
| 2011 |
Sucic S, El-Kasaby A, Kudlacek O, Sarker S, Sitte HH, Marin P, Freissmuth M. The serotonin transporter is an exclusive client of the coat protein complex II (COPII) component SEC24C. The Journal of Biological Chemistry. 286: 16482-90. PMID 21454670 DOI: 10.1074/Jbc.M111.230037 |
0.734 |
|
| 2011 |
Parveen Z, Stockner T, Bentele C, Pferschy S, Kraupp M, Freissmuth M, Ecker GF, Chiba P. Molecular dissection of dual pseudosymmetric solute translocation pathways in human P-glycoprotein. Molecular Pharmacology. 79: 443-52. PMID 21177413 DOI: 10.1124/Mol.110.067611 |
0.33 |
|
| 2011 |
Keuerleber S, Gsandtner I, Freissmuth M. From cradle to twilight: the carboxyl terminus directs the fate of the A(2A)-adenosine receptor. Biochimica Et Biophysica Acta. 1808: 1350-7. PMID 20478264 DOI: 10.1016/J.Bbamem.2010.05.009 |
0.358 |
|
| 2011 |
Bergmayr C, Nanoff C, Kudlacek O, Freissmuth M, Gruber CW. The folding interactome of GPCRs Bmc Pharmacology. 11: A41. DOI: 10.1186/1471-2210-11-S2-A41 |
0.331 |
|
| 2011 |
Montgomery T, Sucic S, Steinkellner T, Freissmuth M, Sitte H. Differential regulation of amphetamine-induced serotonergic and dopaminergic efflux by syntaxin 1A Bmc Pharmacology. 11: A38. DOI: 10.1186/1471-2210-11-S2-A38 |
0.399 |
|
| 2011 |
Sohail A, Stolt-Bergner P, Ecker GF, Freissmuth M, Stockner T, Sitte HH, Sandtner W. LRET-based intramolecular distance measurements in LeuTAa Bmc Pharmacology. 11: A21. DOI: 10.1186/1471-2210-11-S2-A21 |
0.35 |
|
| 2011 |
Sucic S, Kern C, Vidovic D, Sarker S, Kudlacek O, Sitte HH, Freissmuth M. Truncations in the amino terminus reveal a region key to supporting amphetamine-induced efflux by the human serotonin transporter Bmc Pharmacology. 11: A20. DOI: 10.1186/1471-2210-11-S2-A20 |
0.72 |
|
| 2010 |
El-Kasaby A, Just H, Malle E, Stolt-Bergner PC, Sitte HH, Freissmuth M, Kudlacek O. Mutations in the carboxyl-terminal SEC24 binding motif of the serotonin transporter impair folding of the transporter. The Journal of Biological Chemistry. 285: 39201-10. PMID 20889976 DOI: 10.1074/Jbc.M110.118000 |
0.434 |
|
| 2010 |
Sarker S, Weissensteiner R, Steiner I, Sitte HH, Ecker GF, Freissmuth M, Sucic S. The high-affinity binding site for tricyclic antidepressants resides in the outer vestibule of the serotonin transporter. Molecular Pharmacology. 78: 1026-35. PMID 20829432 DOI: 10.1124/Mol.110.067538 |
0.718 |
|
| 2010 |
Gruber CW, Muttenthaler M, Freissmuth M. Ligand-based peptide design and combinatorial peptide libraries to target G protein-coupled receptors Current Pharmaceutical Design. 16: 3071-3088. PMID 20687879 DOI: 10.2174/138161210793292474 |
0.33 |
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| 2010 |
Málaga-Diéguez L, Yang Q, Bauer J, Pankevych H, Freissmuth M, Nanoff C. Pharmacochaperoning of the A1 adenosine receptor is contingent on the endoplasmic reticulum. Molecular Pharmacology. 77: 940-52. PMID 20219842 DOI: 10.1124/Mol.110.063511 |
0.364 |
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| 2010 |
Sucic S, Dallinger S, Zdrazil B, Weissensteiner R, Jørgensen TN, Holy M, Kudlacek O, Seidel S, Cha JH, Gether U, Newman AH, Ecker GF, Freissmuth M, Sitte HH. The N terminus of monoamine transporters is a lever required for the action of amphetamines. The Journal of Biological Chemistry. 285: 10924-38. PMID 20118234 DOI: 10.1074/Jbc.M109.083154 |
0.409 |
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| 2010 |
Sitte HH, Freissmuth M. The reverse operation of Na(+)/Cl(-)-coupled neurotransmitter transporters--why amphetamines take two to tango. Journal of Neurochemistry. 112: 340-55. PMID 19891736 DOI: 10.1111/J.1471-4159.2009.06474.X |
0.405 |
|
| 2010 |
Sohail A, Stolt-Bergner P, Ecker GF, Freissmuth M, Sitte H, Sandtner W. Luminescence resonance energy transfer-based intramolecular distance measurements in leucine transporter from Aquifex aeolicus Bmc Pharmacology. 10. DOI: 10.1186/1471-2210-10-S1-A31 |
0.367 |
|
| 2010 |
Thurner P, Keuerleber S, Gsandtner I, Freissmuth M, Zezula J. Tracking the A2A adenosine receptor Bmc Pharmacology. 10. DOI: 10.1186/1471-2210-10-S1-A30 |
0.317 |
|
| 2010 |
Steinkellner T, Kudlacek O, Freissmuth M, Elgersma Y, Sitte H. Calmodulin kinase II regulates amphetamine-induced reverse transport in the dopamine transporter: implications for the importance of the dopamine transporter in Angelman syndrome Bmc Pharmacology. 10. DOI: 10.1186/1471-2210-10-S1-A19 |
0.388 |
|
| 2010 |
El-Kasaby A, Just H, Sitte H, Kudlacek O, Freissmuth M. The role of the carboxyl terminus in folding of the serotonin transporter Bmc Pharmacology. 10. DOI: 10.1186/1471-2210-10-S1-A18 |
0.391 |
|
| 2010 |
Sucic S, El-Kasaby A, Sarker S, Sitte HH, Marin P, Freissmuth M. Concentrative ER export of the serotonin transporter relies exclusively on an interaction with Sec24C Bmc Pharmacology. 10. DOI: 10.1186/1471-2210-10-S1-A11 |
0.74 |
|
| 2009 |
Milan-Lobo L, Gsandtner I, Gaubitzer E, Rünzler D, Buchmayer F, Köhler G, Bonci A, Freissmuth M, Sitte HH. Subtype-specific differences in corticotropin-releasing factor receptor complexes detected by fluorescence spectroscopy. Molecular Pharmacology. 76: 1196-210. PMID 19755522 DOI: 10.1124/Mol.109.059139 |
0.332 |
|
| 2009 |
Sucic S, Dallinger S, Zdrazil B, Kudlacek O, Sandtner W, Ecker GF, Freissmuth M, Sitte HH. Mutations in the amino-terminus impair amphetamine-induced efflux by inducing inward-facing conformations of the serotonin transporter Bmc Pharmacology. 9: A12. DOI: 10.1186/1471-2210-9-S2-A12 |
0.354 |
|
| 2008 |
Reiterer V, Maier S, Sitte HH, Kriz A, Rüegg MA, Hauri HP, Freissmuth M, Farhan H. Sec24- and ARFGAP1-dependent trafficking of GABA transporter-1 is a prerequisite for correct axonal targeting. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 12453-64. PMID 19020038 DOI: 10.1523/Jneurosci.3451-08.2008 |
0.35 |
|
| 2008 |
Mazei-Robison MS, Bowton E, Holy M, Schmudermaier M, Freissmuth M, Sitte HH, Galli A, Blakely RD. Anomalous dopamine release associated with a human dopamine transporter coding variant. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7040-6. PMID 18614672 DOI: 10.1523/Jneurosci.0473-08.2008 |
0.327 |
|
| 2008 |
Meiblitzer-Ruppitsch C, Vetterlein M, Stangl H, Maier S, Neumüller J, Freissmuth M, Pavelka M, Ellinger A. Electron microscopic visualization of fluorescent signals in cellular compartments and organelles by means of DAB-photoconversion. Histochemistry and Cell Biology. 130: 407-19. PMID 18463889 DOI: 10.1007/S00418-008-0429-4 |
0.306 |
|
| 2008 |
Korkhov VM, Milan-Lobo L, Zuber B, Farhan H, Schmid JA, Freissmuth M, Sitte HH. Peptide-based interactions with calnexin target misassembled membrane proteins into endoplasmic reticulum-derived multilamellar bodies. Journal of Molecular Biology. 378: 337-52. PMID 18367207 DOI: 10.1016/J.Jmb.2008.02.056 |
0.36 |
|
| 2008 |
Farhan H, Reiterer V, Kriz A, Hauri HP, Pavelka M, Sitte HH, Freissmuth M. Signal-dependent export of GABA transporter 1 from the ER-Golgi intermediate compartment is specified by a C-terminal motif. Journal of Cell Science. 121: 753-61. PMID 18285449 DOI: 10.1242/Jcs.017681 |
0.366 |
|
| 2008 |
Zezula J, Freissmuth M. The A(2A)-adenosine receptor: a GPCR with unique features? British Journal of Pharmacology. 153: S184-90. PMID 18246094 DOI: 10.1038/Sj.Bjp.0707674 |
0.35 |
|
| 2008 |
Charalambous C, Gsandtner I, Keuerleber S, Milan-Lobo L, Kudlacek O, Freissmuth M, Zezula J. Restricted collision coupling of the A2A receptor revisited: evidence for physical separation of two signaling cascades. The Journal of Biological Chemistry. 283: 9276-88. PMID 18218631 DOI: 10.1074/Jbc.M706275200 |
0.335 |
|
| 2008 |
Glöckel C, Thurner P, Freissmuth M. Selective serotonin reuptake inhibitors induce cell death via the unfolded protein response Bmc Pharmacology. 8: A45. DOI: 10.1186/1471-2210-8-S1-A45 |
0.322 |
|
| 2007 |
Schuster C, Fernbach N, Rix U, Superti-Furga G, Holy M, Freissmuth M, Sitte HH, Sexl V. Selective serotonin reuptake inhibitors--a new modality for the treatment of lymphoma/leukaemia? Biochemical Pharmacology. 74: 1424-35. PMID 17709099 DOI: 10.1186/1471-2210-7-S2-A8 |
0.32 |
|
| 2007 |
Chanrion B, Mannoury la Cour C, Bertaso F, Lerner-Natoli M, Freissmuth M, Millan MJ, Bockaert J, Marin P. Physical interaction between the serotonin transporter and neuronal nitric oxide synthase underlies reciprocal modulation of their activity. Proceedings of the National Academy of Sciences of the United States of America. 104: 8119-24. PMID 17452640 DOI: 10.1073/Pnas.0610964104 |
0.364 |
|
| 2007 |
Farhan H, Reiterer V, Korkhov VM, Schmid JA, Freissmuth M, Sitte HH. Concentrative export from the endoplasmic reticulum of the gamma-aminobutyric acid transporter 1 requires binding to SEC24D. The Journal of Biological Chemistry. 282: 7679-89. PMID 17210573 DOI: 10.1074/Jbc.M609720200 |
0.386 |
|
| 2007 |
Farhan H, Freissmuth M, Sitte HH. Oligomerization of neurotransmitter transporters: a ticket from the endoplasmic reticulum to the plasma membrane. Handbook of Experimental Pharmacology. 233-49. PMID 16722239 DOI: 10.1007/3-540-29784-7_12 |
0.384 |
|
| 2007 |
Charalambous C, Zezula J, Freissmuth M. Receptor G protein coupling and the cytoskeleton Bmc Pharmacology. 7: A76. DOI: 10.1186/1471-2210-7-S2-A76 |
0.307 |
|
| 2006 |
Farhan H, Schuster C, Klinger M, Weisz E, Waxenecker G, Schuster M, Sexl V, Mudde GC, Freissmuth M, Kircheis R. Inhibition of xenograft tumor growth and down-regulation of ErbB receptors by an antibody directed against Lewis Y antigen. The Journal of Pharmacology and Experimental Therapeutics. 319: 1459-66. PMID 16963623 DOI: 10.1124/Jpet.106.107318 |
0.323 |
|
| 2006 |
Gsandtner I, Freissmuth M. A tail of two signals: the C terminus of the A(2A)-adenosine receptor recruits alternative signaling pathways. Molecular Pharmacology. 70: 447-9. PMID 16707626 DOI: 10.1124/Mol.106.026757 |
0.356 |
|
| 2006 |
Korkhov VM, Holy M, Freissmuth M, Sitte HH. The conserved glutamate (Glu136) in transmembrane domain 2 of the serotonin transporter is required for the conformational switch in the transport cycle. The Journal of Biological Chemistry. 281: 13439-48. PMID 16527819 DOI: 10.1074/Jbc.M511382200 |
0.388 |
|
| 2006 |
Milojevic T, Reiterer V, Stefan E, Korkhov VM, Dorostkar MM, Ducza E, Ogris E, Boehm S, Freissmuth M, Nanoff C. The ubiquitin-specific protease Usp4 regulates the cell surface level of the A2A receptor. Molecular Pharmacology. 69: 1083-94. PMID 16339847 DOI: 10.1124/Mol.105.015818 |
0.35 |
|
| 2006 |
Nanoff C, Koppensteiner R, Yang Q, Fuerst E, Ahorn H, Freissmuth M. The carboxyl terminus of the Galpha-subunit is the latch for triggered activation of heterotrimeric G proteins. Molecular Pharmacology. 69: 397-405. PMID 16210429 DOI: 10.1124/Mol.105.016725 |
0.362 |
|
| 2005 |
Gsandtner I, Charalambous C, Stefan E, Ogris E, Freissmuth M, Zezula J. Heterotrimeric G protein-independent signaling of a G protein-coupled receptor. Direct binding of ARNO/cytohesin-2 to the carboxyl terminus of the A2A adenosine receptor is necessary for sustained activation of the ERK/MAP kinase pathway. The Journal of Biological Chemistry. 280: 31898-905. PMID 16027149 DOI: 10.1074/Jbc.M506515200 |
0.354 |
|
| 2005 |
Seidel S, Singer EA, Just H, Farhan H, Scholze P, Kudlacek O, Holy M, Koppatz K, Krivanek P, Freissmuth M, Sitte HH. Amphetamines take two to tango: an oligomer-based counter-transport model of neurotransmitter transport explores the amphetamine action. Molecular Pharmacology. 67: 140-51. PMID 15615700 DOI: 10.1124/Mol.67.1.140 |
0.403 |
|
| 2004 |
Korkhov VM, Farhan H, Freissmuth M, Sitte HH. Oligomerization of the {gamma}-aminobutyric acid transporter-1 is driven by an interplay of polar and hydrophobic interactions in transmembrane helix II. The Journal of Biological Chemistry. 279: 55728-36. PMID 15496410 DOI: 10.1074/Jbc.M409449200 |
0.336 |
|
| 2004 |
Hohenegger M, Freissmuth M, Nanoff C. Covalent modification of G-proteins by affinity labeling. Methods in Molecular Biology (Clifton, N.J.). 259: 183-95. PMID 15250493 DOI: 10.1385/1-59259-754-8:183 |
0.325 |
|
| 2004 |
Farhan H, Korkhov VM, Paulitschke V, Dorostkar MM, Scholze P, Kudlacek O, Freissmuth M, Sitte HH. Two discontinuous segments in the carboxyl terminus are required for membrane targeting of the rat gamma-aminobutyric acid transporter-1 (GAT1). The Journal of Biological Chemistry. 279: 28553-63. PMID 15073174 DOI: 10.1074/Jbc.M307325200 |
0.369 |
|
| 2004 |
Klinger M, Farhan H, Just H, Drobny H, Himmler G, Loibner H, Mudde GC, Freissmuth M, Sexl V. Antibodies directed against Lewis-Y antigen inhibit signaling of Lewis-Y modified ErbB receptors. Cancer Research. 64: 1087-93. PMID 14871842 DOI: 10.1158/0008-5472.Can-03-2435 |
0.336 |
|
| 2004 |
Just H, Sitte HH, Schmid JA, Freissmuth M, Kudlacek O. Identification of an additional interaction domain in transmembrane domains 11 and 12 that supports oligomer formation in the human serotonin transporter. The Journal of Biological Chemistry. 279: 6650-7. PMID 14660642 DOI: 10.1074/Jbc.M306092200 |
0.356 |
|
| 2003 |
Sitte HH, Freissmuth M. Oligomer formation by Na+-Cl--coupled neurotransmitter transporters. European Journal of Pharmacology. 479: 229-36. PMID 14612153 DOI: 10.1016/J.Ejphar.2003.08.072 |
0.405 |
|
| 2003 |
Kudlacek O, Just H, Korkhov VM, Vartian N, Klinger M, Pankevych H, Yang Q, Nanoff C, Freissmuth M, Boehm S. The human D2 dopamine receptor synergizes with the A2A adenosine receptor to stimulate adenylyl cyclase in PC12 cells. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1317-27. PMID 12784121 DOI: 10.1038/Sj.Npp.1300181 |
0.344 |
|
| 2003 |
Pankevych H, Korkhov V, Freissmuth M, Nanoff C. Truncation of the A1 adenosine receptor reveals distinct roles of the membrane-proximal carboxyl terminus in receptor folding and G protein coupling. The Journal of Biological Chemistry. 278: 30283-93. PMID 12764156 DOI: 10.1074/Jbc.M212918200 |
0.366 |
|
| 2002 |
Scholze P, Freissmuth M, Sitte HH. Mutations within an intramembrane leucine heptad repeat disrupt oligomer formation of the rat GABA transporter 1. The Journal of Biological Chemistry. 277: 43682-90. PMID 12223478 DOI: 10.1074/Jbc.M205602200 |
0.402 |
|
| 2002 |
Klinger M, Kudlacek O, Seidel MG, Freissmuth M, Sexl V. MAP kinase stimulation by cAMP does not require RAP1 but SRC family kinases. The Journal of Biological Chemistry. 277: 32490-7. PMID 12082090 DOI: 10.1074/Jbc.M200556200 |
0.304 |
|
| 2002 |
Scholze P, Nørregaard L, Singer EA, Freissmuth M, Gether U, Sitte HH. The role of zinc ions in reverse transport mediated by monoamine transporters. The Journal of Biological Chemistry. 277: 21505-13. PMID 11940571 DOI: 10.1074/Jbc.M112265200 |
0.394 |
|
| 2002 |
Kudlacek O, Waldhoer M, Kassack MU, Nickel P, Salmi JI, Freissmuth M, Nanoff C. Biased inhibition by a suramin analogue of A1-adenosine receptor/G protein coupling in fused receptor/G protein tandems: the A1-adenosine receptor is predominantly coupled to Goalpha in human brain. Naunyn-Schmiedeberg's Archives of Pharmacology. 365: 8-16. PMID 11862328 DOI: 10.1007/S00210-001-0493-Y |
0.369 |
|
| 2002 |
Breitweg-Lehmann E, Czupalla C, Storm R, Kudlacek O, Schunack W, Freissmuth M, Nürnberg B. Activation and inhibition of G proteins by lipoamines. Molecular Pharmacology. 61: 628-36. PMID 11854444 DOI: 10.1124/Mol.61.3.628 |
0.316 |
|
| 2002 |
Unterberger U, Moskvina E, Scholze T, Freissmuth M, Boehm S. Inhibition of adenylyl cyclase by neuronal P2Y receptors. British Journal of Pharmacology. 135: 673-84. PMID 11834615 DOI: 10.1038/Sj.Bjp.0704514 |
0.33 |
|
| 2002 |
Klinger M, Freissmuth M, Nanoff C. Adenosine receptors: G protein-mediated signalling and the role of accessory proteins. Cellular Signalling. 14: 99-108. PMID 11781133 DOI: 10.1016/S0898-6568(01)00235-2 |
0.346 |
|
| 2001 |
Klinger M, Bofill-Cardona E, Mayer B, Nanoff C, Freissmuth M, Hohenegger M. Suramin and the suramin analogue NF307 discriminate among calmodulin-binding sites. The Biochemical Journal. 355: 827-33. PMID 11311147 DOI: 10.1042/Bj3550827 |
0.359 |
|
| 2000 |
Schmid JA, Scholze P, Kudlacek O, Freissmuth M, Singer EA, Sitte HH. Oligomerization of the human serotonin transporter and of the rat GABA transporter 1 visualized by fluorescence resonance energy transfer microscopy in living cells. The Journal of Biological Chemistry. 276: 3805-10. PMID 11071889 DOI: 10.1074/Jbc.M007357200 |
0.373 |
|
| 2000 |
Kudlacek O, Mitterauer T, Nanoff C, Hohenegger M, Tang WJ, Freissmuth M, Kleuss C. Inhibition of adenylyl and guanylyl cyclase isoforms by the antiviral drug foscarnet. The Journal of Biological Chemistry. 276: 3010-6. PMID 11050094 DOI: 10.1074/Jbc.M007910200 |
0.323 |
|
| 2000 |
Bofill-Cardona E, Kudlacek O, Yang Q, Ahorn H, Freissmuth M, Nanoff C. Binding of calmodulin to the D2-dopamine receptor reduces receptor signaling by arresting the G protein activation switch. The Journal of Biological Chemistry. 275: 32672-80. PMID 10926927 DOI: 10.1074/Jbc.M002780200 |
0.335 |
|
| 1999 |
O'Connor V, El Far O, Bofill-Cardona E, Nanoff C, Freissmuth M, Karschin A, Airas JM, Betz H, Boehm S. Calmodulin dependence of presynaptic metabotropic glutamate receptor signaling. Science (New York, N.Y.). 286: 1180-4. PMID 10550060 DOI: 10.1126/Science.286.5442.1180 |
0.363 |
|
| 1999 |
Waldhoer M, Wise A, Milligan G, Freissmuth M, Nanoff C. Kinetics of ternary complex formation with fusion proteins composed of the A(1)-adenosine receptor and G protein alpha-subunits. The Journal of Biological Chemistry. 274: 30571-9. PMID 10521440 DOI: 10.1074/Jbc.274.43.30571 |
0.353 |
|
| 1999 |
Seidel MG, Klinger M, Freissmuth M, Höller C. Activation of mitogen-activated protein kinase by the A(2A)-adenosine receptor via a rap1-dependent and via a p21(ras)-dependent pathway. The Journal of Biological Chemistry. 274: 25833-41. PMID 10464324 DOI: 10.1074/Jbc.274.36.25833 |
0.318 |
|
| 1999 |
Freissmuth M, Waldhoer M, Bofill-Cardona E, Nanoff C. G protein antagonists. Trends in Pharmacological Sciences. 20: 237-45. PMID 10366866 DOI: 10.1016/S0165-6147(99)01337-1 |
0.363 |
|
| 1999 |
Höller C, Freissmuth M, Nanoff C. G proteins as drug targets. Cellular and Molecular Life Sciences : Cmls. 55: 257-70. PMID 10188585 DOI: 10.1007/S000180050288 |
0.348 |
|
| 1998 |
Hohenegger M, Waldhoer M, Beindl W, Böing B, Kreimeyer A, Nickel P, Nanoff C, Freissmuth M. Gsalpha-selective G protein antagonists. Proceedings of the National Academy of Sciences of the United States of America. 95: 346-51. PMID 9419378 DOI: 10.1073/Pnas.95.1.346 |
0.343 |
|
| 1998 |
H�ller C, Milligan G, Anderson NG, Freissmuth M. Stimulation of p70S6 kinase phosphorylation by the A2A adenosine receptor in primary human endothelial cells and in CHO cells heterologously expressing the receptor Drug Development Research. 45: 140-150. DOI: 10.1002/(Sici)1098-2299(199811/12)45:3/4<140::Aid-Ddr9>3.0.Co;2-M |
0.31 |
|
| 1997 |
Nanoff C, Waldhoer M, Roka F, Freissmuth M. G protein coupling of the rat A1-adenosine receptor--partial purification of a protein which stabilizes the receptor-G protein association. Neuropharmacology. 36: 1211-9. PMID 9364476 DOI: 10.1016/S0028-3908(97)00135-4 |
0.336 |
|
| 1997 |
Sexl V, Mancusi G, Höller C, Gloria-Maercker E, Schütz W, Freissmuth M. Stimulation of the mitogen-activated protein kinase via the A2A-adenosine receptor in primary human endothelial cells. The Journal of Biological Chemistry. 272: 5792-9. PMID 9038193 DOI: 10.1074/Jbc.272.9.5792 |
0.313 |
|
| 1995 |
Sexl V, Mancusi G, Baumgartner-Parzer S, Schütz W, Freissmuth M. Stimulation of human umbilical vein endothelial cell proliferation by A2-adenosine and beta 2-adrenoceptors. British Journal of Pharmacology. 114: 1577-86. PMID 7599925 DOI: 10.1111/J.1476-5381.1995.Tb14942.X |
0.348 |
|
| 1994 |
Bertin B, Freissmuth M, Jockers R, Strosberg AD, Marullo S. Cellular signaling by an agonist-activated receptor/Gs alpha fusion protein. Proceedings of the National Academy of Sciences of the United States of America. 91: 8827-31. PMID 8090731 DOI: 10.1073/Pnas.91.19.8827 |
0.353 |
|
| 1992 |
Schütz W, Freissmuth M. Reverse intrinsic activity of antagonists on G protein-coupled receptors. Trends in Pharmacological Sciences. 13: 376-80. PMID 1329292 DOI: 10.1016/0165-6147(92)90116-N |
0.345 |
|
| 1992 |
McClue SJ, Selzer E, Freissmuth M, Milligan G. Gi3 does not contribute to the inhibition of adenylate cyclase when stimulation of an alpha 2-adrenergic receptor causes activation of both Gi2 and Gi3. The Biochemical Journal. 565-8. PMID 1318036 DOI: 10.1042/Bj2840565 |
0.323 |
|
| 1991 |
Schütz W, Ströher M, Freissmuth M, Valenta B, Singer EA. Adenosine receptors mediate a pertussis toxin-insensitive prejunctional inhibition of noradrenaline release on a papillary muscle model. Naunyn-Schmiedeberg's Archives of Pharmacology. 343: 311-6. PMID 1907720 DOI: 10.1007/Bf00251132 |
0.335 |
|
| 1991 |
Freissmuth M, Selzer E, Schütz W. Interactions of purified bovine brain A1-adenosine receptors with G-proteins. Reciprocal modulation of agonist and antagonist binding. The Biochemical Journal. 651-6. PMID 1903924 DOI: 10.1042/Bj2750651 |
0.365 |
|
| 1991 |
Freissmuth M, Selzer E, Marullo S, Schütz W, Strosberg AD. Expression of two human beta-adrenergic receptors in Escherichia coli: functional interaction with two forms of the stimulatory G protein. Proceedings of the National Academy of Sciences of the United States of America. 88: 8548-52. PMID 1656450 DOI: 10.1073/Pnas.88.19.8548 |
0.316 |
|
| 1989 |
Freissmuth M, Casey PJ, Gilman AG. G proteins control diverse pathways of transmembrane signaling Faseb Journal. 3: 2125-2139. PMID 2546847 DOI: 10.1096/Fasebj.3.10.2546847 |
0.341 |
|
| 1988 |
Freissmuth M, Nees S, Böck M, Schütz W. Binding of [3H]ouabain to endothelial cells derived from various vascular beds. Basic Research in Cardiology. 82: 544-50. PMID 2829813 DOI: 10.1007/Bf01907224 |
0.325 |
|
| 1987 |
Freissmuth M, Hausleithner V, Tuisl E, Nanoff C, Schütz W. Glomeruli and microvessels of the rabbit kidney contain both A1- and A2-adenosine receptors. Naunyn-Schmiedeberg's Archives of Pharmacology. 335: 438-44. PMID 3600819 DOI: 10.1007/Bf00165560 |
0.319 |
|
| 1986 |
Schütz W, Freissmuth M, Hausleithner V, Tuisl E. Cardiac sarcolemmal purity is essential for the verification of adenylate cyclase inhibition via A1-adenosine receptors. Naunyn-Schmiedeberg's Archives of Pharmacology. 333: 156-62. PMID 3018595 DOI: 10.1007/Bf00506519 |
0.34 |
|
| 1986 |
Hausleithner V, Freissmuth M, Schütz W. Adenosine-receptor-mediated stimulation of low-Km GTPase in guinea-pig cerebral cortex. The Biochemical Journal. 232: 501-4. PMID 3004407 DOI: 10.1042/Bj2320501 |
0.33 |
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