| Year |
Citation |
Score |
| 2024 |
Wang Q, Fu X, Yan Y, Liu T, Xie Y, Song X, Zhou Y, Xu M, Wang P, Fu P, Huang J, Huang N. Structure-Based Identification of Organoruthenium Compounds as Nanomolar Antagonists of Cannabinoid Receptors. Journal of Chemical Information and Modeling. PMID 38215394 DOI: 10.1021/acs.jcim.3c01282 |
0.364 |
|
| 2024 |
Li X, Shen C, Zhu H, Yang Y, Wang Q, Yang J, Huang N. A High-Quality Data Set of Protein-Ligand Binding Interactions Via Comparative Complex Structure Modeling. Journal of Chemical Information and Modeling. PMID 38181418 DOI: 10.1021/acs.jcim.3c01170 |
0.667 |
|
| 2023 |
Nie Y, Qiu Z, Chen S, Chen Z, Song X, Ma Y, Huang N, Cyster JG, Zheng S. Specific binding of GPR174 by endogenous lysophosphatidylserine leads to high constitutive G signaling. Nature Communications. 14: 5901. PMID 37737235 DOI: 10.1038/s41467-023-41654-3 |
0.473 |
|
| 2023 |
Wang Q, Meng F, Xie Y, Wang W, Meng Y, Li L, Liu T, Qi J, Ni X, Zheng S, Huang J, Huang N. In Silico Discovery of Small Molecule Modulators Targeting the Achilles' Heel of SARS-CoV-2 Spike Protein. Acs Central Science. 9: 252-265. PMID 36844485 DOI: 10.1021/acscentsci.2c01190 |
0.345 |
|
| 2022 |
Zhu H, Zhang Y, Li W, Huang N. A Comprehensive Survey of Prospective Structure-Based Virtual Screening for Early Drug Discovery in the Past Fifteen Years. International Journal of Molecular Sciences. 23. PMID 36555602 DOI: 10.3390/ijms232415961 |
0.36 |
|
| 2022 |
Xu M, Shen C, Yang J, Wang Q, Huang N. Systematic Investigation of Docking Failures in Large-Scale Structure-Based Virtual Screening. Acs Omega. 7: 39417-39428. PMID 36340123 DOI: 10.1021/acsomega.2c05826 |
0.656 |
|
| 2022 |
Zhu H, Yang J, Huang N. Assessment of the Generalization Abilities of Machine-Learning Scoring Functions for Structure-Based Virtual Screening. Journal of Chemical Information and Modeling. PMID 36268980 DOI: 10.1021/acs.jcim.2c01149 |
0.652 |
|
| 2022 |
Teng X, Chen S, Wang Q, Chen Z, Wang X, Huang N, Zheng S. Structural insights into G protein activation by D1 dopamine receptor. Science Advances. 8: eabo4158. PMID 35687690 DOI: 10.1126/sciadv.abo4158 |
0.416 |
|
| 2021 |
Chen J, Liu N, Huang Y, Wang Y, Sun Y, Wu Q, Li D, Gao S, Wang HW, Huang N, Qi X, Wang X. Structure of PDE3A-SLFN12 complex and structure-based design for a potent apoptosis inducer of tumor cells. Nature Communications. 12: 6204. PMID 34707099 DOI: 10.1038/s41467-021-26546-8 |
0.309 |
|
| 2020 |
Yang J, Shen C, Huang N. Predicting or Pretending: Artificial Intelligence for Protein-Ligand Interactions Lack of Sufficiently Large and Unbiased Datasets. Frontiers in Pharmacology. 11: 69. PMID 32161539 DOI: 10.3389/fphar.2020.00069 |
0.661 |
|
| 2019 |
Li G, Li W, Xie Y, Wan X, Zheng G, Huang N, Zhou Y. Discovery of Novel Pim-1 Kinase Inhibitors with a Flexible-Receptor Docking Protocol. Journal of Chemical Information and Modeling. PMID 31609618 DOI: 10.1021/acs.jcim.9b00494 |
0.311 |
|
| 2018 |
Wang Y, Du Y, Huang N. A survey of the role of nitrile groups in protein-ligand interactions. Future Medicinal Chemistry. PMID 30518255 DOI: 10.4155/Fmc-2018-0252 |
0.301 |
|
| 2017 |
Wang Y, Sun Y, Cao R, Liu D, Xie Y, Li L, Qi X, Huang N. In Silico Identification of a Novel Hinge-Binding Scaffold for Kinase Inhibitor Discovery. Journal of Medicinal Chemistry. PMID 28945083 DOI: 10.1021/Acs.Jmedchem.7B01075 |
0.377 |
|
| 2016 |
Liu X, Dong T, Zhou Y, Huang N, Lei X. Exploring the Binding Proteins of Glycolipids with Bifunctional Chemical Probes. Angewandte Chemie (International Ed. in English). PMID 27762087 DOI: 10.1002/Anie.201608827 |
0.361 |
|
| 2015 |
Zhou Y, Ma J, Lin X, Huang XP, Wu K, Huang N. Structure-Based Discovery of Novel and Selective 5-Hydroxytryptamine 2B Receptor Antagonists for the Treatment of Irritable Bowel Syndrome. Journal of Medicinal Chemistry. PMID 26700945 DOI: 10.1021/Acs.Jmedchem.5B01631 |
0.404 |
|
| 2015 |
Cao R, Wang Y, Huang N. Discovery of 2-Acylaminothiophene-3-Carboxamides as Multitarget Inhibitors for BCR-ABL Kinase and Microtubules. Journal of Chemical Information and Modeling. PMID 26501568 DOI: 10.1021/Acs.Jcim.5B00540 |
0.431 |
|
| 2015 |
Zhou Y, Huang N. Binding site druggability assessment in fragment-based drug design. Methods in Molecular Biology (Clifton, N.J.). 1289: 13-21. PMID 25709029 DOI: 10.1007/978-1-4939-2486-8_2 |
0.414 |
|
| 2014 |
Yao Q, Zhang L, Wan X, Chen J, Hu L, Ding X, Li L, Karar J, Peng H, Chen S, Huang N, Rauscher FJ, Shao F. Structure and specificity of the bacterial cysteine methyltransferase effector NleE suggests a novel substrate in human DNA repair pathway. Plos Pathogens. 10: e1004522. PMID 25412445 DOI: 10.1371/Journal.Ppat.1004522 |
0.405 |
|
| 2014 |
Yao Q, Lu Q, Wan X, Song F, Xu Y, Hu M, Zamyatina A, Liu X, Huang N, Zhu P, Shao F. A structural mechanism for bacterial autotransporter glycosylation by a dodecameric heptosyltransferase family. Elife. 3. PMID 25310236 DOI: 10.7554/Elife.03714 |
0.328 |
|
| 2014 |
Cao R, Huang N, Wang Y. Evaluation and application of MD-PB/SA in structure-based hierarchical virtual screening. Journal of Chemical Information and Modeling. 54: 1987-96. PMID 24977649 DOI: 10.1021/Ci5003203 |
0.503 |
|
| 2014 |
Deng M, Lu Z, Zheng J, Wan X, Chen X, Hirayasu K, Sun H, Lam Y, Chen L, Wang Q, Song C, Huang N, Gao GF, Jiang Y, Arase H, et al. A motif in LILRB2 critical for Angptl2 binding and activation. Blood. 124: 924-35. PMID 24899623 DOI: 10.1182/Blood-2014-01-549162 |
0.361 |
|
| 2014 |
Sun H, Zhao L, Peng S, Huang N. Incorporating replacement free energy of binding-site waters in molecular docking. Proteins. 82: 1765-76. PMID 24549784 DOI: 10.1002/Prot.24530 |
0.428 |
|
| 2014 |
Li W, Wan X, Zeng F, Xie Y, Wang Y, Zhang W, Li L, Huang N. More than just a GPCR ligand: structure-based discovery of thioridazine derivatives as Pim-1 kinase inhibitors Med. Chem. Commun.. 5: 507-511. DOI: 10.1039/C4Md00030G |
0.432 |
|
| 2013 |
Cao R, Li W, Sun HZ, Zhou Y, Huang N. [Computational chemistry in structure-based drug design]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica. 48: 1041-52. PMID 24133970 |
0.324 |
|
| 2013 |
Wan X, Ma Y, McClendon CL, Huang LJ, Huang N. Ab initio modeling and experimental assessment of Janus Kinase 2 (JAK2) kinase-pseudokinase complex structure. Plos Computational Biology. 9: e1003022. PMID 23592968 DOI: 10.1371/Journal.Pcbi.1003022 |
0.361 |
|
| 2013 |
Wan X, Zhang W, Li L, Xie Y, Li W, Huang N. A new target for an old drug: identifying mitoxantrone as a nanomolar inhibitor of PIM1 kinase via kinome-wide selectivity modeling. Journal of Medicinal Chemistry. 56: 2619-29. PMID 23442188 DOI: 10.1021/Jm400045Y |
0.337 |
|
| 2012 |
Yao Q, Cui J, Wang J, Li T, Wan X, Luo T, Gong YN, Xu Y, Huang N, Shao F. Structural mechanism of ubiquitin and NEDD8 deamidation catalyzed by bacterial effectors that induce macrophage-specific apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 109: 20395-400. PMID 23175788 DOI: 10.1073/Pnas.1210831109 |
0.369 |
|
| 2012 |
Cao R, Liu M, Yin M, Liu Q, Wang Y, Huang N. Discovery of novel tubulin inhibitors via structure-based hierarchical virtual screening. Journal of Chemical Information and Modeling. 52: 2730-40. PMID 22992059 DOI: 10.1021/Ci300302C |
0.485 |
|
| 2012 |
Lin X, Huang XP, Chen G, Whaley R, Peng S, Wang Y, Zhang G, Wang SX, Wang S, Roth BL, Huang N. Life beyond kinases: structure-based discovery of sorafenib as nanomolar antagonist of 5-HT receptors. Journal of Medicinal Chemistry. 55: 5749-59. PMID 22694093 DOI: 10.1021/Jm300338M |
0.33 |
|
| 2012 |
Peng S, Lin X, Guo Z, Huang N. Identifying multiple-target ligands via computational chemogenomics approaches. Current Topics in Medicinal Chemistry. 12: 1363-75. PMID 22690683 DOI: 10.2174/156802612801319016 |
0.469 |
|
| 2012 |
Christofferson AJ, Huang N. How to benchmark methods for structure-based virtual screening of large compound libraries. Methods in Molecular Biology (Clifton, N.J.). 819: 187-95. PMID 22183538 DOI: 10.1007/978-1-61779-465-0_13 |
0.45 |
|
| 2011 |
Christofferson A, Zhao L, Sun H, Huang Z, Huang N. Theoretical studies of the base pair fidelity of selenium-modified DNA. The Journal of Physical Chemistry. B. 115: 10041-8. PMID 21770426 DOI: 10.1021/Jp204204X |
0.402 |
|
| 2011 |
Pei Q, Christofferson A, Zhang H, Chai J, Huang N. Computational investigation of the enzymatic mechanisms of phosphothreonine lyase. Biophysical Chemistry. 157: 16-23. PMID 21558045 DOI: 10.1016/J.Bpc.2011.04.002 |
0.308 |
|
| 2010 |
Huang N, Jacobson MP. Binding-site assessment by virtual fragment screening. Plos One. 5: e10109. PMID 20404926 DOI: 10.1371/Journal.Pone.0010109 |
0.635 |
|
| 2009 |
Irwin JJ, Shoichet BK, Mysinger MM, Huang N, Colizzi F, Wassam P, Cao Y. Automated docking screens: a feasibility study. Journal of Medicinal Chemistry. 52: 5712-20. PMID 19719084 DOI: 10.1021/Jm9006966 |
0.726 |
|
| 2009 |
Rapp CS, Schonbrun C, Jacobson MP, Kalyanaraman C, Huang N. Automated site preparation in physics-based rescoring of receptor ligand complexes. Proteins. 77: 52-61. PMID 19382204 DOI: 10.1002/Prot.22415 |
0.635 |
|
| 2008 |
Huang Z, Feng Y, Chen D, Wu X, Huang S, Wang X, Xiao X, Li W, Huang N, Gu L, Zhong G, Chai J. Structural basis for activation and inhibition of the secreted chlamydia protease CPAF. Cell Host & Microbe. 4: 529-42. PMID 19064254 DOI: 10.1016/J.Chom.2008.10.005 |
0.309 |
|
| 2008 |
Huang N, Shoichet BK. Exploiting ordered waters in molecular docking. Journal of Medicinal Chemistry. 51: 4862-5. PMID 18680357 DOI: 10.1021/Jm8006239 |
0.541 |
|
| 2008 |
Chen L, Wang H, Zhang J, Gu L, Huang N, Zhou JM, Chai J. Structural basis for the catalytic mechanism of phosphothreonine lyase. Nature Structural & Molecular Biology. 15: 101-2. PMID 18084305 DOI: 10.1038/Nsmb1329 |
0.323 |
|
| 2007 |
Huang N, Jacobson MP. Physics-based methods for studying protein-ligand interactions. Current Opinion in Drug Discovery & Development. 10: 325-31. PMID 17554859 |
0.6 |
|
| 2006 |
Huang N, Kalyanaraman C, Bernacki K, Jacobson MP. Molecular mechanics methods for predicting protein-ligand binding. Physical Chemistry Chemical Physics : Pccp. 8: 5166-77. PMID 17203140 DOI: 10.1039/B608269F |
0.642 |
|
| 2006 |
Huang N, Shoichet BK, Irwin JJ. Benchmarking sets for molecular docking. Journal of Medicinal Chemistry. 49: 6789-801. PMID 17154509 DOI: 10.1021/Jm0608356 |
0.617 |
|
| 2006 |
Banavali NK, Huang N, MacKerell AD. Conserved patterns in backbone torsional changes allow for single base flipping from duplex DNA with minimal distortion of the double helix. The Journal of Physical Chemistry. B. 110: 10997-1004. PMID 16771353 DOI: 10.1021/Jp0561322 |
0.712 |
|
| 2006 |
Huang N, Kalyanaraman C, Irwin JJ, Jacobson MP. Physics-based scoring of protein-ligand complexes: enrichment of known inhibitors in large-scale virtual screening. Journal of Chemical Information and Modeling. 46: 243-53. PMID 16426060 DOI: 10.1021/Ci0502855 |
0.655 |
|
| 2005 |
Anisimov VM, Lamoureux G, Vorobyov IV, Huang N, Roux B, MacKerell AD. Determination of Electrostatic Parameters for a Polarizable Force Field Based on the Classical Drude Oscillator. Journal of Chemical Theory and Computation. 1: 153-68. PMID 26641126 DOI: 10.1021/Ct049930P |
0.503 |
|
| 2005 |
Huang N, MacKerell AD. Specificity in protein-DNA interactions: energetic recognition by the (cytosine-C5)-methyltransferase from HhaI. Journal of Molecular Biology. 345: 265-74. PMID 15571720 DOI: 10.1016/J.Jmb.2004.10.042 |
0.598 |
|
| 2004 |
Huang N, MacKerell AD. Atomistic view of base flipping in DNA. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 362: 1439-60. PMID 15306460 DOI: 10.1098/Rsta.2004.1383 |
0.598 |
|
| 2004 |
Horton JR, Ratner G, Banavali NK, Huang N, Choi Y, Maier MA, Marquez VE, MacKerell AD, Cheng X. Caught in the act: visualization of an intermediate in the DNA base-flipping pathway induced by HhaI methyltransferase. Nucleic Acids Research. 32: 3877-86. PMID 15273274 DOI: 10.1093/Nar/Gkh701 |
0.721 |
|
| 2004 |
Huang N, Nagarsekar A, Xia G, Hayashi J, MacKerell AD. Identification of non-phosphate-containing small molecular weight inhibitors of the tyrosine kinase p56 Lck SH2 domain via in silico screening against the pY + 3 binding site. Journal of Medicinal Chemistry. 47: 3502-11. PMID 15214778 DOI: 10.1021/Jm030470E |
0.577 |
|
| 2003 |
Peng H, Huang N, Qi J, Xie P, Xu C, Wang J, Yang C. Identification of novel inhibitors of BCR-ABL tyrosine kinase via virtual screening. Bioorganic & Medicinal Chemistry Letters. 13: 3693-9. PMID 14552760 DOI: 10.1016/J.Bmcl.2003.08.014 |
0.314 |
|
| 2003 |
Pan Y, Huang N, Cho S, MacKerell AD. Consideration of molecular weight during compound selection in virtual target-based database screening Journal of Chemical Information and Computer Sciences. 43: 267-272. PMID 12546562 DOI: 10.1021/Ci020055F |
0.565 |
|
| 2003 |
Huang N, Banavali NK, MacKerell AD. Protein-facilitated base flipping in DNA by cytosine-5-methyltransferase. Proceedings of the National Academy of Sciences of the United States of America. 100: 68-73. PMID 12506195 DOI: 10.1073/Pnas.0135427100 |
0.708 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2009 |
Yao Q, Cui J, Zhu Y, Wang G, Hu L, Long C, Cao R, Liu X, Huang N, Chen S, Liu L, Shao F. A bacterial type III effector family uses the papain-like hydrolytic activity to arrest the host cell cycle. Proceedings of the National Academy of Sciences of the United States of America. 106: 3716-21. PMID 19225106 DOI: 10.1073/Pnas.0900212106 |
0.298 |
|
| 2021 |
Wang Q, Zhou Y, Huang J, Huang N. Structure, Function, and Pharmaceutical Ligands of 5-Hydroxytryptamine 2B Receptor. Pharmaceuticals (Basel, Switzerland). 14. PMID 33498477 DOI: 10.3390/ph14020076 |
0.297 |
|
| 2013 |
Wu Y, Dai X, Huang N, Zhao L. A partition function-based weighting scheme in force field parameter development using ab initio calculation results in global configurational space. Journal of Computational Chemistry. 34: 1271-82. PMID 23420684 DOI: 10.1002/Jcc.23249 |
0.295 |
|
| 2020 |
Gao L, Su C, Du X, Wang R, Chen S, Zhou Y, Liu C, Liu X, Tian R, Zhang L, Xie K, Chen S, Guo Q, Guo L, Hano Y, ... ... Huang N, et al. FAD-dependent enzyme-catalysed intermolecular [4+2] cycloaddition in natural product biosynthesis. Nature Chemistry. PMID 32451436 DOI: 10.1038/S41557-020-0467-7 |
0.293 |
|
| 2013 |
Wang Y, Liu M, Cao R, Zhang W, Yin M, Xiao X, Liu Q, Huang N. A soluble bis-chelated gold(I) diphosphine compound with strong anticancer activity and low toxicity. Journal of Medicinal Chemistry. 56: 1455-66. PMID 23362983 DOI: 10.1021/Jm3009822 |
0.292 |
|
| 2014 |
Zhou Y, Wu C, Zhao L, Huang N. Exploring the early stages of the pH-induced conformational change of influenza hemagglutinin. Proteins. 82: 2412-28. PMID 24854389 DOI: 10.1002/Prot.24606 |
0.289 |
|
| 2012 |
Chen P, Song Z, Qi Y, Feng X, Xu N, Sun Y, Wu X, Yao X, Mao Q, Li X, Dong W, Wan X, Huang N, Shen X, Liang Z, et al. Molecular determinants of enterovirus 71 viral entry: cleft around GLN-172 on VP1 protein interacts with variable region on scavenge receptor B 2. The Journal of Biological Chemistry. 287: 6406-20. PMID 22219187 DOI: 10.1074/Jbc.M111.301622 |
0.288 |
|
| 2019 |
Jones AX, Cao Y, Tang YL, Wang JH, Ding YH, Tan H, Chen ZL, Fang RQ, Yin J, Chen RC, Zhu X, She Y, Huang N, Shao F, Ye K, et al. Improving mass spectrometry analysis of protein structures with arginine-selective chemical cross-linkers. Nature Communications. 10: 3911. PMID 31477730 DOI: 10.1038/S41467-019-11917-Z |
0.287 |
|
| 2011 |
Zhao L, Wu C, Huang N. Mutual solubilities study for binary mixtures of dipropylene glycol dimethyl ether and water via molecular dynamics simulation and AMOEBA polarizable force field Fluid Phase Equilibria. 310: 32-38. DOI: 10.1016/J.Fluid.2011.06.014 |
0.281 |
|
| 2013 |
Zeng FQ, Peng SM, Li L, Mu LB, Zhang ZH, Zhang ZY, Huang N. Structure-based identification of drug-like inhibitors of p300 histone acetyltransferase. Yao Xue Xue Bao = Acta Pharmaceutica Sinica. 48: 700-8. PMID 23888693 |
0.279 |
|
| 2015 |
Dong T, Li C, Wang X, Dian L, Zhang X, Li L, Chen S, Cao R, Li L, Huang N, He S, Lei X. Ainsliadimer A selectively inhibits IKKα/β by covalently binding a conserved cysteine. Nature Communications. 6: 6522. PMID 25813672 DOI: 10.1038/Ncomms7522 |
0.278 |
|
| 2021 |
Han P, Su C, Zhang Y, Bai C, Zheng A, Qiao C, Wang Q, Niu S, Chen Q, Zhang Y, Li W, Liao H, Li J, Zhang Z, Cho H, ... ... Huang N, et al. Molecular insights into receptor binding of recent emerging SARS-CoV-2 variants. Nature Communications. 12: 6103. PMID 34671049 DOI: 10.1038/s41467-021-26401-w |
0.272 |
|
| 2015 |
Hu Z, Wan X, Hao R, Zhang H, Li L, Li L, Xie Q, Wang P, Gao Y, Chen S, Wei M, Luan Z, Zhang A, Huang N, Chen L. Phosphorylation of mutationally introduced tyrosine in the activation loop of HER2 confers gain-of-function activity. Plos One. 10: e0123623. PMID 25853726 DOI: 10.1371/Journal.Pone.0123623 |
0.263 |
|
| 2002 |
Huang N, Mackerell AD. An ab Initio Quantum Mechanical Study of Hydrogen-Bonded Complexes of Biological Interest Journal of Physical Chemistry A. 106: 7820-7827. DOI: 10.1021/Jp020059N |
0.258 |
|
| 2007 |
Wang GF, Huang N, Meng ZH, Liu QH. Identification of novel inhibitors of the streptogramin group A acetyltransferase via virtual screening. Yao Xue Xue Bao = Acta Pharmaceutica Sinica. 42: 47-53. PMID 17520806 |
0.258 |
|
| 2014 |
Yao Q, Lu Q, Wan X, Song F, Xu Y, Hu M, Zamyatina A, Liu X, Huang N, Zhu P, Shao F. Author response: A structural mechanism for bacterial autotransporter glycosylation by a dodecameric heptosyltransferase family Elife. DOI: 10.7554/Elife.03714.022 |
0.255 |
|
| 2020 |
Li G, Zhang W, Xie Y, Li Y, Cao R, Zheng G, Huang N, Zhou Y. Structure-Based Optimization of 10-DEBC Derivatives as Potent and Selective Pim-1 Kinase Inhibitors. Journal of Chemical Information and Modeling. PMID 32407627 DOI: 10.1021/Acs.Jcim.0C00245 |
0.244 |
|
| 2019 |
Wang Y, Fu Q, Zhou Y, Du Y, Huang N. The Replacement of Protein Binding-site Waters Contributes to Favorable Halogen Bond Interactions. Journal of Chemical Information and Modeling. PMID 31187992 DOI: 10.1021/Acs.Jcim.9B00128 |
0.244 |
|
| 2020 |
Lin H, Zhang X, Liu L, Fu Q, Zang C, Ding Y, Su Y, Xu Z, He S, Yang X, Wei X, Mao H, Cui Y, Wei Y, Zhou C, ... ... Huang N, et al. Basis for metabolite-dependent Cullin-RING ligase deneddylation by the COP9 signalosome. Proceedings of the National Academy of Sciences of the United States of America. PMID 32047038 DOI: 10.1073/Pnas.1911998117 |
0.242 |
|
| 2007 |
Ji Q, Zhou Y, Peng H, Huang N, Qi J, Xiong DS, Gao YD, Yang M, Yang CZ. [Design and activity determination of small molecular inhibitors of integrin alphavbeta3]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae. 29: 347-52. PMID 17633460 |
0.229 |
|
| 2017 |
Ren S, Caforio A, Yang Q, Sun B, Yu F, Zhu X, Wang J, Dou C, Fu Q, Huang N, Sun Q, Nie C, Qi S, Gong X, He J, et al. Structural and mechanistic insights into the biosynthesis of CDP-archaeol in membranes. Cell Research. PMID 28961231 DOI: 10.1038/Cr.2017.122 |
0.21 |
|
| 2018 |
Zhou Y, Wang Y, Li P, Huang XP, Qi X, Du Y, Huang N. Exploring Halogen Bonds in 5-Hydroxytryptamine 2B Receptor-Ligand Interactions. Acs Medicinal Chemistry Letters. 9: 1019-1024. PMID 30344910 DOI: 10.1021/Acsmedchemlett.8B00300 |
0.208 |
|
| 2022 |
Li L, Liao H, Meng Y, Li W, Han P, Liu K, Wang Q, Li D, Zhang Y, Wang L, Fan Z, Zhang Y, Wang Q, Zhao X, Sun Y, ... Huang N, et al. Structural basis of human ACE2 higher binding affinity to currently circulating Omicron SARS-CoV-2 sub-variants BA.2 and BA.1.1. Cell. PMID 35809570 DOI: 10.1016/j.cell.2022.06.023 |
0.196 |
|
| 2016 |
Zhu Q, Venzke D, Walimbe AS, Anderson ME, Fu Q, Kinch LN, Wang W, Chen X, Grishin NV, Huang N, Yu L, Dixon JE, Campbell KP, Xiao J. Structure of protein O-mannose kinase reveals a unique active site architecture. Elife. 5. PMID 27879205 DOI: 10.7554/Elife.22238 |
0.194 |
|
| 2024 |
Wang P, Li Y, Yang J, Li Z, Ren X, Meng Q, Li P, Qin L, Li W, Xie Y, Hou N, Huang N. Structure-Based Identification of Kelch-like ECH-Associated Protein 1 as a Pharmacological Target of Electrophile-Containing Catechol--Methyltransferase Inhibitors. Acs Pharmacology & Translational Science. 7: 693-706. PMID 38481699 DOI: 10.1021/acsptsci.3c00281 |
0.194 |
|
| 2004 |
Peng H, Qi J, Huang N, Xie P, Wang JX, Yang CZ. [Molecular design and biological activity of BCR-ABL tyrosine kinase inhibitors]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae. 26: 145-9. PMID 15171550 |
0.191 |
|
| 2022 |
Xu J, Shen C, Xie Y, Qiu B, Ren X, Zhou Y, Li G, Zheng G, Huang N. Design, synthesis, and bioactivity evaluation of macrocyclic benzo[b]pyrido[4,3-e][1,4]oxazine derivatives as novel Pim-1 kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 128874. PMID 35779826 DOI: 10.1016/j.bmcl.2022.128874 |
0.175 |
|
| 2022 |
Wang JH, Tang YL, Gong Z, Jain R, Xiao F, Zhou Y, Tan D, Li Q, Huang N, Liu SQ, Ye K, Tang C, Dong MQ, Lei X. Characterization of protein unfolding by fast cross-linking mass spectrometry using di-ortho-phthalaldehyde cross-linkers. Nature Communications. 13: 1468. PMID 35304446 DOI: 10.1038/s41467-022-28879-4 |
0.174 |
|
| 2017 |
Zhang L, Sun H, Chen Z, Liu Z, Huang N, Qian F. Intermolecular interactions between co-encapsulated drugs inhibit drug crystallization and enhance colloidal stability of polymeric micelles. Molecular Pharmaceutics. PMID 28829143 DOI: 10.1021/acs.molpharmaceut.7b00591 |
0.171 |
|
| 2018 |
Lei Z, Chai N, Tian M, Zhang Y, Wang G, Liu J, Tian Z, Yi X, Chen D, Li X, Yu P, Hu H, Xu B, Jian C, Bian Z, ... ... Huang N, et al. Novel peptide GX1 inhibits angiogenesis by specifically binding to transglutaminase-2 in the tumorous endothelial cells of gastric cancer. Cell Death & Disease. 9: 579. PMID 29785022 DOI: 10.1038/s41419-018-0594-x |
0.157 |
|
| 2016 |
Xiao W, Adhikari S, Dahal U, Chen YS, Hao YJ, Sun BF, Sun HY, Li A, Ping XL, Lai WY, Wang X, Ma HL, Huang CM, Yang Y, Huang N, et al. Nuclear m(6)A Reader YTHDC1 Regulates mRNA Splicing. Molecular Cell. PMID 26876937 DOI: 10.1016/j.molcel.2016.01.012 |
0.148 |
|
| 2024 |
Lv M, Cui CX, Huang N, Wu M, Wang Q, Gao T, Zheng Y, Liu W, Huang Y, Li H, Ma T, Ye L. Precisely engineering asymmetric atomic CoN4 by electron donating and extracting for oxygen reduction reaction. Angewandte Chemie (International Ed. in English). e202315802. PMID 38453646 DOI: 10.1002/anie.202315802 |
0.146 |
|
| 2019 |
Peng S, Xiao W, Ju D, Sun B, Hou N, Liu Q, Wang Y, Zhao H, Gao C, Zhang S, Cao R, Li P, Huang H, Ma Y, Wang Y, ... ... Huang N, et al. Identification of entacapone as a chemical inhibitor of FTO mediating metabolic regulation through FOXO1. Science Translational Medicine. 11. PMID 30996080 DOI: 10.2210/Pdb6Ak4/Pdb |
0.143 |
|
| 2019 |
Zhang C, Qin S, Hu B, Lv J, Yang Z, Yan W, Wang J, Huang N, Huang Z. Disruption of nucleobase stacking to restore reactivity. Nucleosides, Nucleotides & Nucleic Acids. 1-11. PMID 30922168 DOI: 10.1080/15257770.2019.1576882 |
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| 2020 |
Ju D, Zhang W, Yan J, Zhao H, Li W, Wang J, Liao M, Xu Z, Wang Z, Zhou G, Mei L, Hou N, Ying S, Cai T, Chen S, ... ... Huang N, et al. Chemical perturbations reveal that RUVBL2 regulates the circadian phase in mammals. Science Translational Medicine. 12. PMID 32376767 DOI: 10.1126/Scitranslmed.Aba0769 |
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| 2022 |
Li G, Cheng Y, Han C, Song C, Huang N, Du Y. Pyrazole-containing pharmaceuticals: target, pharmacological activity, and their SAR studies. Rsc Medicinal Chemistry. 13: 1300-1321. PMID 36439976 DOI: 10.1039/d2md00206j |
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| 2016 |
Liu JJ, Niu CY, Wu Y, Tan D, Wang Y, Ye MD, Liu Y, Zhao W, Zhou K, Liu QS, Dai J, Yang X, Dong MQ, Huang N, Wang HW. CryoEM structure of yeast cytoplasmic exosome complex. Cell Research. PMID 27174052 DOI: 10.1038/Cr.2016.56 |
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| 2024 |
Huo L, Lv M, Li M, Ni X, Guan J, Liu J, Mei S, Yang Y, Zhu M, Feng Q, Geng P, Hou J, Huang N, Liu W, Kong X, et al. Amorphous MnO Lamellae Encapsulated Covalent Triazine Polymer-Derived Multi-Heteroatoms-Doped Carbon for Orr/Oer Bifunctional Electrocatalysis. Advanced Materials (Deerfield Beach, Fla.). e2312868. PMID 38241728 DOI: 10.1002/adma.202312868 |
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| 2016 |
He L, Zhou X, Huang N, Li H, Tian J, Li T, Yao K, Wu G, Nyachoti CM, Kim SW, Yin Y. The Mechanism of AMPK Regulation on Glucose, Lipid and Protein Metabolic Homeostasis and Its Related Physiologically Nutritional Significance. Current Protein & Peptide Science. PMID 27356941 |
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| 2023 |
Zheng Y, Khan NA, Ni X, Zhang KAI, Shen Y, Huang N, Kong XY, Ye L. Emerging covalent triazine framework-based nanomaterials for electrochemical energy storage and conversion. Chemical Communications (Cambridge, England). PMID 37132271 DOI: 10.1039/d3cc00712j |
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| 2021 |
Wei Y, Tian L, Sun P, Huang N, Lv X, Fang L, Sun X. Synthesis of Ni₃Bi₂S₂ Coupled with N-Doped Carbon Sheets as Electrocatalyst for Triiodide and Oxygen Reduction. Journal of Nanoscience and Nanotechnology. 21: 4740-4748. PMID 33691860 DOI: 10.1166/jnn.2021.19345 |
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| 2016 |
Bao C, Li F, Wang J, Sun P, Huang N, Sun Y, Fang L, Wang L, Sun X. One-Pot Solvothermal in Situ Growth of 1D Single-Crystalline NiSe on Ni Foil as Efficient and Stable Transparent Conductive Oxide Free Counter Electrodes for Dye-Sensitized Solar Cells. Acs Applied Materials & Interfaces. 8: 32788-32796. PMID 27934175 DOI: 10.1021/acsami.6b10198 |
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| 2017 |
He L, Li H, Huang N, Zhou X, Tian J, Li T, Wu J, Tian Y, Yin Y, Yao K. Alpha-ketoglutarate suppresses the NF-κB-mediated inflammatory pathway and enhances the PXR-regulated detoxification pathway. Oncotarget. 8: 102974-102988. PMID 29262538 DOI: 10.18632/oncotarget.16875 |
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| 2017 |
He L, Li H, Huang N, Zhou X, Tian J, Li T, Wu J, Tian Y, Yin Y, Yao K. Alpha-ketoglutarate suppresses the NF-κB-mediated inflammatory pathway and enhances the PXR-regulated detoxification pathway. Oncotarget. PMID 28430654 DOI: 10.18632/oncotarget.16875 |
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| 2005 |
Anisimov VM, Lamoureux G, Vorobyov IV, Huang N, Roux B, MacKerell AD. Determination of electrostatic parameters for a polarizable force field based on the classical Drude oscillator Journal of Chemical Theory and Computation. 1: 153-168. DOI: 10.1021/ct049930p |
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| 2023 |
Liu W, Xu R, Pan W, Li C, Huang N, Huang Y, Ye L. Solar to H2O2 energy conversion by the photothermal effect of the polymeric photocatalyst via two-channel pathway. Chemsuschem. e202300015. PMID 36905229 DOI: 10.1002/cssc.202300015 |
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| 2024 |
Deng Y, Liu W, Xu R, Gao R, Huang N, Zheng Y, Huang Y, Li H, Kong XY, Ye L. Reduction of Superoxide Radical Intermediate by Polydopamine for Efficient Hydrogen Peroxide Photosynthesis. Angewandte Chemie (International Ed. in English). e202319216. PMID 38337143 DOI: 10.1002/anie.202319216 |
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| 2023 |
Li M, Lv M, Zheng Y, Zhu M, Feng Q, Guan J, Yu X, Shen Y, Hou J, Lu Y, Huang N, Ye L. Bimetallic-Coordinated Covalent Triazine Framework-Derived FeNi Alloy Nanoparticle-Decorated Coral-Like Nanocarbons for Oxygen Electrocatalysis. Acs Applied Materials & Interfaces. PMID 38150331 DOI: 10.1021/acsami.3c14448 |
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| 2017 |
Yang X, Yang Y, Sun BF, Chen YS, Xu JW, Lai WY, Li A, Wang X, Bhattarai DP, Xiao W, Sun HY, Zhu Q, Ma HL, Adhikari S, Sun M, ... ... Huang N, et al. 5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader. Cell Research. PMID 28418038 DOI: 10.1038/cr.2017.55 |
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| 2023 |
Luo S, Li Y, Yang W, Gao W, Yu H, Huang N. C-Dot-Embedded SiO Concentric Microspheres for Bright Fluorescent Photonic Pigments. Acs Applied Materials & Interfaces. PMID 37395624 DOI: 10.1021/acsami.3c05022 |
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| 2017 |
He L, Huang N, Li H, Tian J, Zhou X, Li T, Yao K, Wu G, Yin Y. The AMPK/α-ketoglutarate axis regulates intestinal water and ions homeostasis in young pigs. Journal of Agricultural and Food Chemistry. PMID 28241728 DOI: 10.1021/Acs.Jafc.7B00324 |
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| 2020 |
Peng S, Li W, Hou N, Huang N. A Review of 1-Regulated Metabolic Diseases and Related Drug Discoveries. Cells. 9. PMID 31936903 DOI: 10.3390/cells9010184 |
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| 2013 |
Liang L, Liu Y, Bu C, Guo K, Sun W, Huang N, Peng T, Sebo B, Pan M, Liu W, Guo S, Zhao XZ. Highly uniform, bifunctional core/double-shell-structured β-NaYF4:Er3+, Yb3+ @ SiO2@TiO2 hexagonal sub-microprisms for high-performance dye sensitized solar cells. Advanced Materials (Deerfield Beach, Fla.). 25: 2174-80. PMID 23420696 DOI: 10.1002/Adma.201204847 |
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| 2023 |
Su Y, Luo Y, Zhang P, Lin H, Pu W, Zhang H, Wang H, Hao Y, Xiao Y, Zhang X, Wei X, Nie S, Zhang K, Fu Q, Chen H, ... Huang N, et al. Glucose-induced CRL4-p53 axis amplifies glycometabolism to drive tumorigenesis. Molecular Cell. PMID 37390815 DOI: 10.1016/j.molcel.2023.06.010 |
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| 2017 |
He L, Zhou X, Huang N, Li H, Li T, Yao K, Tian Y, Hu CA, Yin Y. Functions of pregnane X receptor in self-detoxification. Amino Acids. PMID 28534176 DOI: 10.1007/S00726-017-2435-0 |
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| 2013 |
Bu C, Liu Y, Yu Z, You S, Huang N, Liang L, Zhao XZ. Highly transparent carbon counter electrode prepared via an in situ carbonization method for bifacial dye-sensitized solar cells. Acs Applied Materials & Interfaces. 5: 7432-8. PMID 23806279 DOI: 10.1021/am4017472 |
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| 2013 |
Peng T, Sun W, Sun X, Huang N, Liu Y, Bu C, Guo S, Zhao XZ. Direct tri-constituent co-assembly of highly ordered mesoporous carbon counter electrode for dye-sensitized solar cells. Nanoscale. 5: 337-41. PMID 23165970 DOI: 10.1039/c2nr32536e |
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| 2017 |
He L, Zhou X, Huang N, Li H, Cui Z, Tian J, Jiang Q, Liu S, Wu J, Li T, Yao K, Yin Y. Administration of alpha-ketoglutarate improves epithelial restitution under stress injury in early-weaning piglets. Oncotarget. 8: 91965-91978. PMID 29190890 DOI: 10.18632/oncotarget.20555 |
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He L, Li H, Huang N, Tian J, Liu Z, Zhou X, Yao K, Li T, Yin Y. Effects of Alpha-Ketoglutarate on Glutamine Metabolism in Piglet Enterocytes in Vivo and in Vitro. Journal of Agricultural and Food Chemistry. PMID 27018713 DOI: 10.1021/acs.jafc.6b00433 |
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| 2019 |
Sun L, Ma L, Zhang H, Cao Y, Wang C, Hou N, Huang N, von Deneen KM, Zhao C, Shi Y, Pan Y, Wang M, Ji G, Nie Y. Deficiency Reduces Anxiety- and Depression-Like Behaviors in Mice via Alterations in Gut Microbiota. Theranostics. 9: 721-733. PMID 30809304 DOI: 10.7150/thno.31562 |
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| 2011 |
Colonno R, Huang N, Huang Q, Peng E, Huq A, Lau M, Bencsik M, Zhong M, Li L. 1200 CHARACTERIZATION AND IDENTIFICATION OF PPI-437, PPI-668 AND PPI-833 AS POTENT AND SELECTIVE HCV NS5A INHIBITORS WITH ACTIVITY AGAINST ALL HCV GENOTYPES Journal of Hepatology. 54: S474. DOI: 10.1016/S0168-8278(11)61202-6 |
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| 2011 |
Colonno R, Huang Q, Huang N, Huq A, Peng E, Lau M, Bencsik M, Zhong M, Li L. 1199 COMPREHENSIVE ANALYSIS SHOWS CONSERVED PATHWAYS TO RESISTANCE ACROSS ALL MAJOR HCV GENOTYPES FOR A PANEL OF NS5A INHIBITORS Journal of Hepatology. 54: S473-S474. DOI: 10.1016/S0168-8278(11)61201-4 |
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| 2012 |
Liu Y, Zhai H, Guo F, Huang N, Sun W, Bu C, Peng T, Yuan J, Zhao X. Synergistic effect of surface plasmon resonance and constructed hierarchical TiO2 spheres for dye-sensitized solar cells. Nanoscale. 4: 6863-9. PMID 23023266 DOI: 10.1039/C2Nr31954C |
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