JIanzhong Chen - Publications

Affiliations: 
Surgery University of Michigan, Ann Arbor, Ann Arbor, MI 

69 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Zhu Z, Chen J, Wang G, Elsherbini A, Zhong L, Jiang X, Qin H, Tripathi P, Zhi W, Spassieva SD, Morris AJ, Bieberich E. Ceramide regulates interaction of Hsd17b4 with Pex5 and function of peroxisomes. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. PMID 31176039 DOI: 10.1016/j.bbalip.2019.05.017  0.32
2019 Chen J, Wang X, Pang L, Zhang JZH, Zhu T. Effect of mutations on binding of ligands to guanine riboswitch probed by free energy perturbation and molecular dynamics simulations. Nucleic Acids Research. PMID 31173143 DOI: 10.1093/nar/gkz499  0.56
2019 Li B, Chen J, Zhang Z, Gridnev ID, Zhang W. Ni-Catalyzed Asymmetric Hydrogenation of N-Sulfonyl Imines. Angewandte Chemie (International Ed. in English). PMID 30920711 DOI: 10.1002/anie.201902576  0.52
2019 Chen J, Pang L, Wang W, Wang L, Zhang JZH, Zhu T. Decoding molecular mechanism of inhibitor bindings to CDK2 using molecular dynamics simulations and binding free energy calculations. Journal of Biomolecular Structure & Dynamics. 1-23. PMID 30843759 DOI: 10.1080/07391102.2019.1591304  0.56
2018 Chen F, Zhang Z, Chen J. Infective endocarditis caused by Lactococcus lactis subsp. lactis and Pediococcus pentosaceus: A case report and literature review. Medicine. 97: e13658. PMID 30558065 DOI: 10.1097/MD.0000000000013658  0.52
2018 Chen J, Zhang Z, Li B, Li F, Wang Y, Zhao M, Gridnev ID, Imamoto T, Zhang W. Pd(OAc)-catalyzed asymmetric hydrogenation of sterically hindered N-tosylimines. Nature Communications. 9: 5000. PMID 30479338 DOI: 10.1038/s41467-018-07462-w  0.52
2018 Chen J, Peng C, Wang J, Zhu W. Exploring Molecular Mechanism of Allosteric Inhibitor to Relieve Drug Resistance of Multiple Mutations in HIV-1 Protease by Enhanced Conformational Sampling. Proteins. PMID 30260044 DOI: 10.1002/prot.25610  0.68
2018 Su J, Liu X, Zhang S, Yan F, Zhang Q, Chen J. Insight into Selective Mechanism of class of I-BRD9 Inhibitors toward BRD9 Based on Molecular Dynamics Simulations. Chemical Biology & Drug Design. PMID 30225973 DOI: 10.1111/cbdd.13398  0.8
2018 Yan F, Liu X, Zhang S, Su J, Zhang Q, Chen J. Electrostatic Interaction-Mediated Conformational Changes of Adipocyte Fatty Acid Binding Protein Probed by Molecular Dynamics Simulation. Journal of Biomolecular Structure & Dynamics. 1-32. PMID 30193557 DOI: 10.1080/07391102.2018.1520648  0.8
2018 Yan F, Liu X, Zhang S, Su J, Zhang Q, Chen J. Molecular Dynamics Exploration of Selectivity of Dual Inhibitors 5M7, 65X, and 65Z toward Fatty Acid Binding Proteins 4 and 5. International Journal of Molecular Sciences. 19. PMID 30142969 DOI: 10.3390/ijms19092496  0.8
2018 Wen K, Wu Z, Chen B, Chen J, Zhang W. Pd(ii)-Catalyzed aerobic 1,2-difunctionalization of conjugated dienes: efficient synthesis of morpholines and 2-morpholones. Organic & Biomolecular Chemistry. PMID 30027979 DOI: 10.1039/c8ob01291a  0.52
2018 Chen J, Wang J, Pang L, Zhu W. Inhibiting mechanism of small molecule toward the p53-MDM2 interaction: A Molecular Dynamics Exploration. Chemical Biology & Drug Design. PMID 29877036 DOI: 10.1111/cbdd.13345  0.68
2018 Sun A, Zhang H, Pang F, Niu G, Chen J, Chen F, Zhang J. Essential genes of the macrophage response to exposure. Cellular & Molecular Biology Letters. 23: 25. PMID 29849669 DOI: 10.1186/s11658-018-0090-4  0.4
2018 Liu W, Mu F, Liu T, Xu H, Chen J, Jia N, Zhang Y, Dou F, Li Y, Wen A, Ding Y. UPLC-Q/TOF-MS based metabonomics revealed protective effect of Terminalia chebula extract on ischemic stroke rats. Rejuvenation Research. PMID 29804491 DOI: 10.1089/rej.2018.2082  0.32
2018 Zhang J, Liu C, Wang X, Chen J, Zhang Z, Zhang W. Rhodium-catalyzed asymmetric hydrogenation of β-branched enamides for the synthesis of β-stereogenic amines. Chemical Communications (Cambridge, England). PMID 29796543 DOI: 10.1039/c8cc02798f  0.52
2018 Chen W, Cheng Y, Chen J, Chen J, Jiang K, Zhou Y, Jia L. Pharmacokinetic differences of mifepristone between sexes in animals. Journal of Pharmaceutical and Biomedical Analysis. 154: 108-115. PMID 29544105 DOI: 10.1016/j.jpba.2018.03.008  0.4
2017 Huo X, Fu J, He X, Chen J, Xie F, Zhang W. Pd/Cu dual catalysis: highly enantioselective access to α-substituted α-amino acids and α-amino amides. Chemical Communications (Cambridge, England). PMID 29256570 DOI: 10.1039/c7cc08732b  0.52
2017 Chen W, Xiao Y, Chen J, Liu J, Shao J, Li T, Zhu Y, Ma J, Gao Y, Wang J, Xu J, Lu Y, Jia L. Sex-related pharmacokinetic differences and mechanisms of metapristone (RU486 metabolite). Scientific Reports. 7: 17190. PMID 29215040 DOI: 10.1038/s41598-017-17225-0  0.68
2017 Su J, Liu X, Zhang S, Yan F, Zhang Q, Chen J. A Theoretical Insight into Selectivity of Inhibitors toward two Domains of Bromodomain-Containing Protein 4 Using Molecular Dynamics Simulations. Chemical Biology & Drug Design. PMID 29139214 DOI: 10.1111/cbdd.13148  0.8
2017 Chen J, Wang J, Zhu W. Mutation L1196M-induced conformational changes and the drug resistant mechanism of anaplastic lymphoma kinase studied by free energy perturbation and umbrella sampling. Physical Chemistry Chemical Physics : Pccp. PMID 29109998 DOI: 10.1039/c7cp05418a  0.68
2017 Yan F, Liu X, Zhang S, Su J, Zhang Q, Chen J. Computational revelation of Binding Mechanisms of Inhibitors to Endocellular Protein Tyrosine Phosphatase 1B Using Molecular Dynamics Simulations. Journal of Biomolecular Structure & Dynamics. 1-36. PMID 29048995 DOI: 10.1080/07391102.2017.1394221  0.8
2017 Chen J, Tao F, Zhang B, Chen Q, Qiu Y, Luo Q, Gen Y, Meng J, Zhang J, Lu H. Elevated Squamous Cell Carcinoma Antigen, Cytokeratin 19 Fragment, and Carcinoembryonic Antigen Levels in Diabetic Nephropathy. International Journal of Endocrinology. 2017: 5304391. PMID 28744310 DOI: 10.1155/2017/5304391  0.32
2017 Jiang Z, Qian J, Dong H, Yang J, Yu X, Chen J, Chen H, Shi Q, Jia L. The traditional Chinese medicine Achyranthes bidentata and our de novo conception of its metastatic chemoprevention: from phytochemistry to pharmacology. Scientific Reports. 7: 3888. PMID 28634392 DOI: 10.1038/s41598-017-02054-y  0.36
2017 Su J, Liu X, Zhang S, Yan F, Zhang Q, Chen J. A computational insight into binding modes of inhibitors XD29, XD35, and XD28 to bromodomain-containing protein 4 based on molecular dynamics simulations. Journal of Biomolecular Structure & Dynamics. 1-13. PMID 28466681 DOI: 10.1080/07391102.2017.1317666  0.8
2017 Chen J, Wang J, Zhu W. Zinc ion-induced conformational changes in new Delphi metallo-β-lactamase 1 probed by molecular dynamics simulations and umbrella sampling. Physical Chemistry Chemical Physics : Pccp. PMID 28079218 DOI: 10.1039/c6cp08105c  0.68
2016 Chen J, Wang J, Zhu W. Molecular Mechanism and Energy Basis of Conformational Diversity of Antibody SPE7 Revealed by Molecular Dynamics Simulation and Principal Component Analysis. Scientific Reports. 6: 36900. PMID 27830740 DOI: 10.1038/srep36900  0.68
2016 Ye C, Zhang W, Wang S, Jiang S, Yu Y, Chen E, Xue D, Chen J, He R. Icariin Promotes Tendon-Bone Healing during Repair of Rotator Cuff Tears: A Biomechanical and Histological Study. International Journal of Molecular Sciences. 17. PMID 27792147 DOI: 10.3390/ijms17111780  0.52
2016 Qian H, Chen J, Pan Y, Chen J. Molecular Modeling Studies of 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors through Receptor-Based 3D-QSAR and Molecular Dynamics Simulations. Molecules (Basel, Switzerland). 21. PMID 27657020 DOI: 10.3390/molecules21091222  0.48
2016 Liu Y, Chen J, Zhang Z, Qin J, Zhao M, Zhang W. One-pot sequential asymmetric hydrogenation of β-aryl-β-aryloxy acroleins. Organic & Biomolecular Chemistry. 14: 7099-7102. PMID 27439010 DOI: 10.1039/c6ob00871b  0.52
2016 Chen J, Zhang Z, Liu D, Zhang W. Palladium-Catalyzed Chemo- and Enantioselective C-O Bond Cleavage of α-Acyloxy Ketones by Hydrogenolysis. Angewandte Chemie (International Ed. in English). PMID 27312573 DOI: 10.1002/anie.201603590  0.52
2016 Guo F, Sun Y, Yang X, Chen X, Zhao B, Zhuang N, Chen J. Growth, Faraday and inverse Faraday characteristics of Tb2Ti2O7 crystal. Optics Express. 24: 5734-5743. PMID 27136771  0.32
2016 Hu Q, Chen J, Zhang Z, Liu Y, Zhang W. Rh-Catalyzed One-Pot Sequential Asymmetric Hydrogenation of α-Dehydroamino Ketones for the Synthesis of Chiral Cyclic trans-β-Amino Alcohols. Organic Letters. 18: 1290-3. PMID 26987883 DOI: 10.1021/acs.orglett.6b00212  0.52
2016 Wang J, Chen J, Zhu Y, Zheng N, Liu J, Xiao Y, Lu Y, Dong H, Xie J, Yu S, Shao J, Jia L. In vitro and in vivo efficacy and safety evaluation of metapristone and mifepristone as cancer metastatic chemopreventive agents. Biomedicine & Pharmacotherapy = BioméDecine & PharmacothéRapie. 78: 291-300. PMID 26898454 DOI: 10.1016/j.biopha.2016.01.017  0.32
2015 Chen J, Wang J, Zhang Q, Chen K, Zhu W. Probing Origin of Binding Difference of inhibitors to MDM2 and MDMX by Polarizable Molecular Dynamics Simulation and QM/MM-GBSA Calculation. Scientific Reports. 5: 17421. PMID 26616018 DOI: 10.1038/srep17421  0.8
2015 Zhang Z, Hu Q, Wang Y, Chen J, Zhang W. Rh-Catalyzed Asymmetric Hydrogenation of Cyclic α-Dehydroamino Ketones. Organic Letters. PMID 26497221 DOI: 10.1021/acs.orglett.5b02733  0.52
2015 Chen J, Wang X, Zhu T, Zhang Q, Zhang JZ. A Comparative Insight into Amprenavir Resistance of Mutations V32I, G48V, I50V, I54V and I84V in HIV-1 Protease Based on Thermodynamic Integration and MM-PBSA Methods. Journal of Chemical Information and Modeling. PMID 26317593 DOI: 10.1021/acs.jcim.5b00173  0.8
2015 Zhu Z, Wu X, Lv B, Wu G, Wang J, Jiang W, Li P, He J, Chen J, Chen M, Bao D, Zhang J, Tan Q, Tang X. A new approach for breeding low-temperature resistant Volvariella volvacea strains: Genome shuffling in edible fungi. Biotechnology and Applied Biochemistry. PMID 26234394 DOI: 10.1002/bab.1420  0.68
2015 Yang J, Lyu B, Zhu W, Chen J, He J, Tang S. [A retrospective cohort comparison of esophageal carcinoma between thoracoscopic and laparoscopic esophagectomy and open esophagectomy]. Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]. 53: 378-81. PMID 26082255  0.68
2015 Xiang L, Chi T, Tang Q, Yang X, Ou M, Chen X, Yu X, Chen J, Ho RJ, Shao J, Jia L. A pentacyclic triterpene natural product, ursolic acid and its prodrug US597 inhibit targets within cell adhesion pathway and prevent cancer metastasis. Oncotarget. 6: 9295-312. PMID 25823660  0.4
2015 Miao C, Zhou G, Qin M, Chen J, Li C, He H. [Pulchinenoside inhibits the fibroblast-like synoviocytes apoptosis in adjuvant arthritis rats]. Zhong Nan Da Xue Xue Bao. Yi Xue Ban = Journal of Central South University. Medical Sciences. 40: 144-9. PMID 25769322 DOI: 10.11817/j.issn.1672-7347.2015.02.005  0.48
2015 Pan L, Hu H, Wang X, Yu L, Jiang H, Chen J, Lou Y, Zeng S. Inhibitory effects of neochamaejasmin B on P-glycoprotein in MDCK-hMDR1 cells and molecular docking of NCB binding in P-glycoprotein. Molecules (Basel, Switzerland). 20: 2931-48. PMID 25679052 DOI: 10.3390/molecules20022931  0.32
2015 Gao Y, Li Z, Xie X, Wang C, You J, Mo F, Jin B, Chen J, Shao J, Chen H, Jia L. Dendrimeric anticancer prodrugs for targeted delivery of ursolic acid to folate receptor-expressing cancer cells: synthesis and biological evaluation. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 70: 55-63. PMID 25638419 DOI: 10.1016/j.ejps.2015.01.007  0.32
2015 Chen J, Wang J, Zhang Q, Chen K, Zhu W. A comparative study of trypsin specificity based on QM/MM molecular dynamics simulation and QM/MM GBSA calculation. Journal of Biomolecular Structure & Dynamics. 33: 2606-18. PMID 25562613 DOI: 10.1080/07391102.2014.1003146  0.8
2015 Dong H, Yang X, Xie J, Xiang L, Li Y, Ou M, Chi T, Liu Z, Yu S, Gao Y, Chen J, Shao J, Jia L. UP12, a novel ursolic acid derivative with potential for targeting multiple signaling pathways in hepatocellular carcinoma. Biochemical Pharmacology. 93: 151-62. PMID 25522955 DOI: 10.1016/j.bcp.2014.11.014  0.32
2015 Jiang W, Yao F, He J, Lv B, Fang W, Zhu W, He G, Chen J, He J. Downregulation of VGLL4 in the progression of esophageal squamous cell carcinoma. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 36: 1289-97. PMID 25352025 DOI: 10.1007/s13277-014-2701-7  0.68
2014 Wang J, Jiang Z, Xiang L, Li Y, Ou M, Yang X, Shao J, Lu Y, Lin L, Chen J, Dai Y, Jia L. Synergism of ursolic acid derivative US597 with 2-deoxy-D-glucose to preferentially induce tumor cell death by dual-targeting of apoptosis and glycolysis. Scientific Reports. 4: 5006. PMID 25833312 DOI: 10.1038/srep05006  0.68
2014 Chen J, Liang Z, Wang W, Yi C, Zhang S, Zhang Q. Revealing origin of decrease in potency of darunavir and amprenavir against HIV-2 relative to HIV-1 protease by molecular dynamics simulations. Scientific Reports. 4: 6872. PMID 25362963 DOI: 10.1038/srep06872  0.8
2014 Wang R, Wang C, Cao Y, Zhu Z, Yang C, Chen J, Qing FL, Tan W. Trifluoromethylated Nucleic Acid Analogues Capable of Self-Assembly through Hydrophobic Interactions. Chemical Science (Royal Society of Chemistry : 2010). 5: 4076-4081. PMID 25285193 DOI: 10.1039/C4SC01162G  0.32
2014 Guo M, Pan Y, Zhang R, Cao Y, Chen J, Pan Y. The specific cleavage of lactone linkage to open-loop in cyclic lipopeptide during negative ESI tandem mass spectrometry: the hydrogen bond interaction effect of 4-ethyl guaiacol. Plos One. 9: e104835. PMID 25144459 DOI: 10.1371/journal.pone.0104835  0.48
2014 Chen J, Wang J, Zhu W. Binding modes of three inhibitors 8CA, F8A and I4A to A-FABP studied based on molecular dynamics simulation. Plos One. 9: e99862. PMID 24918907 DOI: 10.1371/journal.pone.0099862  0.68
2014 Chen J, Wang J, Shao J, Gao Y, Xu J, Yu S, Liu Z, Jia L. The unique pharmacological characteristics of mifepristone (RU486): from terminating pregnancy to preventing cancer metastasis. Medicinal Research Reviews. 34: 979-1000. PMID 24585714 DOI: 10.1002/med.21311  0.68
2014 Yu L, Pu J, Zuo M, Zhang X, Cao Y, Chen S, Lou Y, Zhou Q, Hu H, Jiang H, Chen J, Zeng S. Hepatic glucuronidation of isoneochamaejasmin a from the traditional Chinese medicine Stellera chamaejasme L. Root. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 735-43. PMID 24452863 DOI: 10.1124/dmd.113.055962  0.48
2014 Wang J, Chen J, Wan L, Shao J, Lu Y, Zhu Y, Ou M, Yu S, Chen H, Jia L. Synthesis, spectral characterization, and in vitro cellular activities of metapristone, a potential cancer metastatic chemopreventive agent derived from mifepristone (RU486). The Aaps Journal. 16: 289-98. PMID 24442753 DOI: 10.1208/s12248-013-9559-2  0.68
2014 Gao Y, Shao J, Jiang Z, Chen J, Gu S, Yu S, Zheng K, Jia L. Drug enterohepatic circulation and disposition: constituents of systems pharmacokinetics. Drug Discovery Today. 19: 326-40. PMID 24295642 DOI: 10.1016/j.drudis.2013.11.020  0.4
2013 Chen J, Wang J, Zhu W, Li G. A computational analysis of binding modes and conformation changes of MDM2 induced by p53 and inhibitor bindings. Journal of Computer-Aided Molecular Design. 27: 965-74. PMID 24264557 DOI: 10.1007/s10822-013-9693-z  0.68
2013 Chen J, Liu D, Butt N, Li C, Fan D, Liu Y, Zhang W. Palladium-catalyzed asymmetric hydrogenation of α-acyloxy-1-arylethanones. Angewandte Chemie (International Ed. in English). 52: 11632-6. PMID 24038964 DOI: 10.1002/anie.201306231  0.52
2013 Tang L, Zhao L, Hong L, Yang F, Sheng R, Chen J, Shi Y, Zhou N, Hu Y. Design and synthesis of novel 3-substituted-indole derivatives as selective H3 receptor antagonists and potent free radical scavengers. Bioorganic & Medicinal Chemistry. 21: 5936-44. PMID 23978359 DOI: 10.1016/j.bmc.2013.07.051  0.32
2013 Zhuang N, Liu C, Jia L, Wei L, Cai J, Guo Y, Zhang Y, Hu X, Chen J, Chen X, Tang Y. Clean unzipping by steam etching to synthesize graphene nanoribbons. Nanotechnology. 24: 325604. PMID 23867357 DOI: 10.1088/0957-4484/24/32/325604  0.36
2013 Xie J, Shao J, Lu Y, Chen J, Wang J, Yu S, Jia L. Separation of ginseng active ingredients and their roles in cancer metastasis supplementary therapy. Current Drug Metabolism. 14: 616-23. PMID 23701161  0.68
2013 Dong X, Zhao Y, Huang X, Lin K, Chen J, Wei E, Liu T, Hu Y. Structure-based drug design using GPCR homology modeling: toward the discovery of novel selective CysLT2 antagonists. European Journal of Medicinal Chemistry. 62: 754-63. PMID 23455026 DOI: 10.1016/j.ejmech.2013.01.041  0.32
2012 Liu D, Sui Y, Wang T, Huang C, Chen J, You X. Two isomorphous Mn(II) and Co(II) 5-amino-tetrazolate coordination polymers with magnetic Δ-chains: crystal structures and magnetic properties. Dalton Transactions (Cambridge, England : 2003). 41: 5301-6. PMID 22411404 DOI: 10.1039/c2dt12495e  0.48
2011 Dong X, Zhou X, Jing H, Chen J, Liu T, Yang B, He Q, Hu Y. Pharmacophore identification, virtual screening and biological evaluation of prenylated flavonoids derivatives as PKB/Akt1 inhibitors. European Journal of Medicinal Chemistry. 46: 5949-58. PMID 22027102 DOI: 10.1016/j.ejmech.2011.10.006  0.32
2011 Chen J, Wang J, Xu B, Zhu W, Li G. Insight into mechanism of small molecule inhibitors of the MDM2-p53 interaction: molecular dynamics simulation and free energy analysis. Journal of Molecular Graphics & Modelling. 30: 46-53. PMID 21764342 DOI: 10.1016/j.jmgm.2011.06.003  0.68
2011 Lu J, Fu C, Chen J. Structure, growth, and optical properties of TbAl3(BO3)4 single crystal. Applied Optics. 50: 116-9. PMID 21221169  0.32
2010 Hou J, Pan B, Niu X, Chen J, Xing B. Sulfamethoxazole sorption by sediment fractions in comparison to pyrene and bisphenol A. Environmental Pollution (Barking, Essex : 1987). 158: 2826-32. PMID 20609505 DOI: 10.1016/j.envpol.2010.06.023  0.32
2010 Chen J, Dai J, Zhang H, Wang C, Zhou G, Han Z, Liu Z. Bioaccumulation of microcystin and its oxidative stress in the apple (Malus pumila). Ecotoxicology (London, England). 19: 796-803. PMID 20052542 DOI: 10.1007/s10646-009-0456-5  0.32
2010 Chen J, Zhang S, Liu X, Zhang Q. Insights into drug resistance of mutations D30N and I50V to HIV-1 protease inhibitor TMC-114: free energy calculation and molecular dynamic simulation. Journal of Molecular Modeling. 16: 459-68. PMID 19629548 DOI: 10.1007/s00894-009-0553-7  0.8
2009 Chen J, Chou G, Yang L, Wang C, Wang Z. [Determination of norisoboldine in Radix Lindera by RP-HPLC]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 34: 2774-6. PMID 20209913  0.32
2009 Chen J, Yang M, Hu G, Shi S, Yi C, Zhang Q. Insights into the functional role of protonation states in the HIV-1 protease-BEA369 complex: molecular dynamics simulations and free energy calculations. Journal of Molecular Modeling. 15: 1245-52. PMID 19294437 DOI: 10.1007/s00894-009-0452-y  0.8
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