Frank Tortella - Publications

Affiliations: 
Neuropharmacology and Molecular Neurobiology Walter Reed Army Institute of Research, Silver Spring, MD, United States 

102 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Foreman B, Lee H, Mizrahi MA, Hartings JA, Ngwenya LB, Privitera M, Tortella FC, Zhang N, Kramer JH. Seizures and Cognitive Outcome After Traumatic Brain Injury: A Post Hoc Analysis. Neurocritical Care. PMID 34232458 DOI: 10.1007/s12028-021-01267-4  0.389
2019 Lee H, Mizrahi MA, Hartings JA, Sharma S, Pahren L, Ngwenya LB, Moseley BD, Privitera M, Tortella FC, Foreman B. Continuous Electroencephalography After Moderate to Severe Traumatic Brain Injury. Critical Care Medicine. PMID 30624278 DOI: 10.1097/Ccm.0000000000003639  0.47
2018 Yang Z, Zhu T, Mondello S, Akel M, Wong AT, Kothari IM, Lin F, Shear DA, Gilsdorf J, Leung LY, Bramlett HM, Dixon CE, Dietrich WD, Hayes RL, Povlishock J, ... Tortella FC, et al. Serum-based phospho-neurofilament-heavy protein as theranostic biomarker in three models of traumatic brain injury: an Operation Brain Trauma Therapy (OBTT) study. Journal of Neurotrauma. PMID 29987972 DOI: 10.1089/Neu.2017.5586  0.468
2018 Kochanek PM, Bramlett HM, Dixon CE, Dietrich WD, Mondello S, Wang KKW, Hayes RL, Lafrenaye A, Povlishock JT, Tortella FC, Poloyac SM, Empey P, Shear DA. Operation Brain Trauma Therapy: 2016 Update. Military Medicine. 183: 303-312. PMID 29635589 DOI: 10.1093/Milmed/Usx184  0.38
2017 Cernak I, Stein DG, Elder GA, Ahlers S, Curley K, DePalma RG, Duda J, Ikonomovic M, Iverson GL, Kobeissy F, Koliatsos VE, Leggieri MJ, Pacifico AM, Smith DH, Swanson R, ... ... Tortella FC, et al. Preclinical modelling of militarily relevant traumatic brain injuries: Challenges and recommendations for future directions. Brain Injury. 31: 1168-1176. PMID 28981339 DOI: 10.1080/02699052.2016.1274779  0.417
2017 Lu XM, Cao Y, Mountney A, Liao Z, Shear DA, Tortella FC. Combination therapy of levetiracetam and gabapentin against nonconvulsive seizures induced by penetrating traumatic brain injury. The Journal of Trauma and Acute Care Surgery. PMID 28452872 DOI: 10.1097/Ta.0000000000001470  0.401
2017 Mountney A, Boutte A, Cartagena CM, Flerlage WJ, Johnson D, Rho C, Lu XM, Yarnell AM, Marcsisin SR, Sousa J, Vuong C, Zottig VE, Leung LY, Deng-Bryant Y, Gilsdorf J, ... Tortella FC, et al. Functional and molecular correlates following single and repeated rat closed-head concussion; indices of vulnerability following brain injury. Journal of Neurotrauma. PMID 28326890 DOI: 10.1089/Neu.2016.4679  0.507
2016 Leung LY, Deng-Bryant Y, Cardiff K, Winter M, Tortella F, Shear D. Neurochemical changes following combined hypoxemia and hemorrhagic shock in a rat model of penetrating ballistic-like brain injury: A microdialysis study. The Journal of Trauma and Acute Care Surgery. 81: 860-867. PMID 27769083 DOI: 10.1097/Ta.0000000000001206  0.564
2016 Deng-Bryant Y, Leung LY, Caudle K, Tortella F, Shear D. Cognitive Evaluation Using Morris Water Maze in Neurotrauma. Methods in Molecular Biology (Clifton, N.J.). 1462: 539-51. PMID 27604737 DOI: 10.1007/978-1-4939-3816-2_29  0.458
2016 Leung LY, Deng-Bryant Y, Shear D, Tortella F. Experimental Models Combining TBI, Hemorrhagic Shock, and Hypoxemia. Methods in Molecular Biology (Clifton, N.J.). 1462: 445-58. PMID 27604733 DOI: 10.1007/978-1-4939-3816-2_25  0.509
2016 Deng-Bryant Y, Readnower R, Leung LY, Tortella F, Shear D. Methods of Drug Delivery in Neurotrauma. Methods in Molecular Biology (Clifton, N.J.). 1462: 89-100. PMID 27604714 DOI: 10.1007/978-1-4939-3816-2_6  0.315
2016 Cartagena CM, Mountney A, Hwang H, Swiercz A, Rammelkamp Z, Boutte AM, Shear DA, Tortella FC, Schmid KE. Subacute Changes in Cleavage Processing of Amyloid Precursor Protein and Tau following Penetrating Traumatic Brain Injury. Plos One. 11: e0158576. PMID 27428544 DOI: 10.1371/Journal.Pone.0158576  0.392
2016 Yarnell AM, Barry ES, Mountney A, Shear D, Tortella F, Grunberg NE. The Revised Neurobehavioral Severity Scale (NSS-R) for Rodents. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. 75: 9.52.1-9.52.16. PMID 27063788 DOI: 10.1002/Cpns.10  0.503
2016 Caudle KL, Lu XM, Mountney A, Shear DA, Tortella FC. Neuroprotection and anti-seizure effects of levetiracetam in a rat model of penetrating ballistic-like brain injury. Restorative Neurology and Neuroscience. PMID 26890099 DOI: 10.3233/Rnn-150580  0.424
2015 Lu XM, Shear DA, Deng-Bryant Y, Leung LY, Wei G, Chen Z, Tortella FC. Comprehensive Evaluation of Neuroprotection Achieved by Extended Selective Brain Cooling Therapy in a Rat Model of Penetrating Ballistic-Like Brain Injury. Therapeutic Hypothermia and Temperature Management. PMID 26684246 DOI: 10.1089/Ther.2015.0017  0.51
2015 Mondello S, Shear DA, Bramlett HM, Dixon CE, Schmid Maj KE, Dietrich WD, Wang KK, Hayes RL, Glushakova O, Catania M, Richieri S, Povlishock J, Tortella FC, Kochanek PM. Insight into Preclinical Models of Traumatic Brain Injury Using Circulating Brain Damage Biomarkers: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26671651 DOI: 10.1089/Neu.2015.4132  0.515
2015 Browning M, Shear DA, Bramlett HM, Dixon CE, Mondello S, Schmid Maj KE, Poloyac SM, Dietrich WD, Hayes RL, Wang KK, Povlishock J, Tortella FC, Kochanek PM. Levetiracetam Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26671550 DOI: 10.1089/Neu.2015.4131  0.355
2015 Kochanek PM, Bramlett HM, Shear DA, Dixon CE, Mondello S, Dietrich WD, Hayes RL, Wang KK, Poloyac SM, Empey P, Povlishock J, Mountney A, Browning M, Deng-Bryant Y, Yan HQ, ... ... Tortella FC, et al. Synthesis of Findings, Current Investigations, and Future Directions: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26671284 DOI: 10.1089/Neu.2015.4133  0.379
2015 Dixon CE, Bramlett HM, Dietrich WD, Shear DA, Yan HQ, Deng-Bryant Y, Mondello S, Wang KK, Hayes RL, Empey P, Povlishock J, Tortella FC, Kochanek PM. Cyclosporine Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26671075 DOI: 10.1089/Neu.2015.4122  0.463
2015 Shear DA, Bramlett HM, Dixon CE, Dietrich WD, Deng-Bryant Y, Schmid Maj KE, Mondello S, Wang KK, Hayes RL, Povlishock J, Kochanek PM, Tortella FC. Nicotinamide Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26670792 DOI: 10.1089/Neu.2015.4115  0.461
2015 Bramlett HM, Dietrich WD, Dixon CE, Shear DA, Schmid Maj KE, Mondello S, Wang KK, Hayes RL, Povlishock J, Tortella FC, Kochanek PM. Erythropoietin Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26670694 DOI: 10.1089/Neu.2015.4116  0.474
2015 Mountney A, Boutte A, Gilsdorf J, Lu XM, Tortella FC, Shear DA. Intravenous Administration of Simvastatin improves Cognitive Outcome following Severe Traumatic Brain Injury in Rats. Journal of Neurotrauma. PMID 26542887 DOI: 10.1089/Neu.2015.4139  0.51
2015 Mountney A, Bramlett HM, Dixon CE, Mondello S, Dietrich WD, Wang KK, Caudle KL, Empey P, Poloyac SM, Hayes RL, Povlishock J, Tortella FC, Kochanek PM, Shear DA. Simvastatin Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26541177 DOI: 10.1089/Neu.2015.4130  0.527
2015 Welch RD, Ayaz SI, Lewis LM, Unden J, Chen JY, Mika VH, Saville B, Tyndall JA, Nash M, Buki A, Barzo P, Hack D, Tortella FC, Schmid K, Hayes RL, et al. Ability of Serum Glial Fibrillary Acidic Protein, Ubiquitin C-Terminal Hydrolase-L1, and S100B to Differentiate Normal and Abnormal Head Computed Tomography Findings in Patients with Suspected Mild or Moderate Traumatic Brain Injury. Journal of Neurotrauma. PMID 26467555 DOI: 10.1089/Neu.2015.4149  0.308
2015 Leung LY, Deng-Bryant Y, Shear D, Tortella F. Combined hypoxemic and hypotensive insults altered physiological responses and neurofunction in a severity-dependent manner following penetrating ballistic-like brain injury in rats. The Journal of Trauma and Acute Care Surgery. 79: S130-8. PMID 26406425 DOI: 10.1097/Ta.0000000000000785  0.586
2015 Smith DH, Hicks M, Johnson VE, Bergstrom D, Cummings D, Noble-Haeusslein L, Hovda D, Whalen M, Ahlers S, LaPlaca M, Tortella F, Duhaime AC, Dixon CE. Preclinical Traumatic Brain Injury Common Data Elements: Towards a Common Language Across Laboratories. Journal of Neurotrauma. PMID 26058402 DOI: 10.1089/Neu.2014.3861  0.37
2015 Bhattacharyya S, Zhang X, Feferman L, Johnson D, Tortella FC, Guizzetti M, Tobacman JK. Decline in arylsulfatase B and Increase in chondroitin 4-sulfotransferase combine to increase chondroitin 4-sulfate in traumatic brain injury. Journal of Neurochemistry. 134: 728-39. PMID 25943740 DOI: 10.1111/Jnc.13156  0.44
2015 Tortella FC, Leung LY. Traumatic Brain Injury and Polytrauma in Theaters of Combat: The Case for Neurotrauma Resuscitation? Shock (Augusta, Ga.). 44: 17-26. PMID 25895144 DOI: 10.1097/Shk.0000000000000380  0.477
2015 Lu XC, Shear DA, Graham PB, Bridson GW, Uttamsingh V, Chen Z, Leung LY, Tortella FC. Dual Therapeutic Effects of C-10068, a Dextromethorphan Derivative, Against Post-Traumatic Nonconvulsive Seizures and Neuroinflammation in a Rat Model of Penetrating Ballistic-Like Brain Injury. Journal of Neurotrauma. PMID 25794265 DOI: 10.1089/Neu.2014.3766  0.32
2015 Boutté AM, Deng-Bryant Y, Johnson D, Tortella FC, Dave JR, Shear DA, Schmid KE. Serum Glial Fibrillary Acidic Protein Predicts Tissue Glial Fibrillary Acidic Protein Break-Down Products and Therapeutic Efficacy after Penetrating Ballistic-Like Brain Injury. Journal of Neurotrauma. PMID 25789543 DOI: 10.1089/neu.2014.3672  0.416
2015 Gajavelli S, Kentaro S, Diaz J, Yokobori S, Spurlock M, Diaz D, Jackson C, Wick A, Zhao W, Leung LY, Shear D, Tortella F, Bullock MR. Glucose and oxygen metabolism after penetrating ballistic-like brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 773-80. PMID 25669903 DOI: 10.1038/Jcbfm.2014.243  0.541
2015 Deng-Bryant Y, Readnower RD, Leung LY, Cunningham TL, Shear DA, Tortella FC. Treatment with amnion-derived cellular cytokine solution (ACCS) induces persistent motor improvement and ameliorates neuroinflammation in a rat model of penetrating ballistic-like brain injury. Restorative Neurology and Neuroscience. 33: 189-203. PMID 25588460 DOI: 10.3233/Rnn-140455  0.453
2015 Buki A, Kovacs N, Czeiter E, Schmid K, Berger RP, Kobeissy F, Italiano D, Hayes RL, Tortella FC, Mezosi E, Schwarcz A, Toth A, Nemes O, Mondello S. Minor and repetitive head injury. Advances and Technical Standards in Neurosurgery. 42: 147-92. PMID 25411149 DOI: 10.1007/978-3-319-09066-5_8  0.506
2014 Mondello S, Tortella FC. Brain Injury Markers: Where are We? Frontiers in Neurology. 5: 145. PMID 25136331 DOI: 10.3389/Fneur.2014.00145  0.438
2014 Cartagena CM, Phillips KL, Tortella FC, Dave JR, Schmid KE. Temporal alterations in aquaporin and transcription factor HIF1α expression following penetrating ballistic-like brain injury (PBBI). Molecular and Cellular Neurosciences. 60: 81-7. PMID 24769105 DOI: 10.1016/j.mcn.2014.04.005  0.43
2014 Leung LY, Larimore Z, Holmes L, Cartagena C, Mountney A, Deng-Bryant Y, Schmid K, Shear D, Tortella F. The WRAIR projectile concussive impact model of mild traumatic brain injury: re-design, testing and preclinical validation. Annals of Biomedical Engineering. 42: 1618-30. PMID 24756867 DOI: 10.1007/S10439-014-1014-8  0.431
2014 Zhang Z, Zoltewicz JS, Mondello S, Newsom KJ, Yang Z, Yang B, Kobeissy F, Guingab J, Glushakova O, Robicsek S, Heaton S, Buki A, Hannay J, Gold MS, Rubenstein R, ... ... Tortella F, et al. Human traumatic brain injury induces autoantibody response against glial fibrillary acidic protein and its breakdown products. Plos One. 9: e92698. PMID 24667434 DOI: 10.1371/Journal.Pone.0092698  0.558
2014 Cunningham TL, Cartagena CM, Lu XC, Konopko M, Dave JR, Tortella FC, Shear DA. Correlations between blood-brain barrier disruption and neuroinflammation in an experimental model of penetrating ballistic-like brain injury. Journal of Neurotrauma. 31: 505-14. PMID 24138024 DOI: 10.1089/Neu.2013.2965  0.438
2014 Mondello S, Schmid K, Berger RP, Kobeissy F, Italiano D, Jeromin A, Hayes RL, Tortella FC, Buki A. The challenge of mild traumatic brain injury: role of biochemical markers in diagnosis of brain damage. Medicinal Research Reviews. 34: 503-31. PMID 23813922 DOI: 10.1002/Med.21295  0.494
2014 Zhang Z, Zoltewicz JS, Mondello S, Newsom KJ, Yang Z, Yang B, Kobeissy F, Guingab J, Glushakova O, Robicsek S, Heaton S, Buki A, Hannay J, Gold MS, Rubenstein R, ... ... Tortella F, et al. TBI autoantibodies colocalized with GFAP in primary rat astrocytes. Plos One. DOI: 10.1371/Journal.Pone.0092698.G007  0.364
2014 Zhang Z, Zoltewicz JS, Mondello S, Newsom KJ, Yang Z, Yang B, Kobeissy F, Guingab J, Glushakova O, Robicsek S, Heaton S, Buki A, Hannay J, Gold MS, Rubenstein R, ... ... Tortella F, et al. Human severe TBI patients developed circulating IgG autoantibodies against brain proteins within the 50-38 kDa range after injury. Plos One. DOI: 10.1371/Journal.Pone.0092698.G001  0.523
2013 Mountney A, Shear DA, Potter B, Marcsisin SR, Sousa J, Melendez V, Tortella FC, Lu XC. Ethosuximide and phenytoin dose-dependently attenuate acute nonconvulsive seizures after traumatic brain injury in rats. Journal of Neurotrauma. 30: 1973-82. PMID 23822888 DOI: 10.1089/Neu.2013.3001  0.388
2013 Shear DA, Tortella FC. A military-centered approach to neuroprotection for traumatic brain injury. Frontiers in Neurology. 4: 73. PMID 23781213 DOI: 10.3389/Fneur.2013.00073  0.415
2013 Feala JD, Abdulhameed MD, Yu C, Dutta B, Yu X, Schmid K, Dave J, Tortella F, Reifman J. Systems biology approaches for discovering biomarkers for traumatic brain injury. Journal of Neurotrauma. 30: 1101-16. PMID 23510232 DOI: 10.1089/Neu.2012.2631  0.509
2013 Leung LY, Wei G, Shear DA, Tortella FC. The acute effects of hemorrhagic shock on cerebral blood flow, brain tissue oxygen tension, and spreading depolarization following penetrating ballistic-like brain injury. Journal of Neurotrauma. 30: 1288-98. PMID 23461630 DOI: 10.1089/Neu.2012.2715  0.437
2013 Zoltewicz JS, Mondello S, Yang B, Newsom KJ, Kobeissy F, Yao C, Lu XC, Dave JR, Shear DA, Schmid K, Rivera V, Cram T, Seaney J, Zhang Z, Wang KK, ... ... Tortella FC, et al. Biomarkers track damage after graded injury severity in a rat model of penetrating brain injury. Journal of Neurotrauma. 30: 1161-9. PMID 23409698 DOI: 10.1089/Neu.2012.2762  0.502
2013 Lu XC, Mountney A, Chen Z, Wei G, Cao Y, Leung LY, Khatri V, Cunningham T, Tortella FC. Similarities and differences of acute nonconvulsive seizures and other epileptic activities following penetrating and ischemic brain injuries in rats. Journal of Neurotrauma. 30: 580-90. PMID 23234254 DOI: 10.1089/Neu.2012.2641  0.402
2013 Mountney A, Leung LY, Pedersen R, Shear D, Tortella F. Longitudinal assessment of gait abnormalities following penetrating ballistic-like brain injury in rats. Journal of Neuroscience Methods. 212: 1-16. PMID 22981945 DOI: 10.1016/J.Jneumeth.2012.08.025  0.545
2013 Cartagena CM, Schmid KE, Phillips KL, Tortella FC, Dave JR. Changes in apoptotic mechanisms following penetrating ballistic-like brain injury. Journal of Molecular Neuroscience : Mn. 49: 301-11. PMID 22684621 DOI: 10.1007/s12031-012-9828-z  0.337
2012 Boutté AM, Yao C, Kobeissy F, May Lu XC, Zhang Z, Wang KK, Schmid K, Tortella FC, Dave JR. Proteomic analysis and brain-specific systems biology in a rodent model of penetrating ballistic-like brain injury. Electrophoresis. 33: 3693-704. PMID 23161467 DOI: 10.1002/Elps.201200196  0.471
2012 Deng-Bryant Y, Chen Z, van der Merwe C, Liao Z, Dave JR, Rupp R, Shear DA, Tortella FC. Long-term administration of amnion-derived cellular cytokine suspension promotes functional recovery in a model of penetrating ballistic-like brain injury. The Journal of Trauma and Acute Care Surgery. 73: S156-64. PMID 22847087 DOI: 10.1097/Ta.0B013E3182625F5F  0.377
2012 Mondello S, Gabrielli A, Catani S, D'Ippolito M, Jeromin A, Ciaramella A, Bossù P, Schmid K, Tortella F, Wang KK, Hayes RL, Formisano R. Increased levels of serum MAP-2 at 6-months correlate with improved outcome in survivors of severe traumatic brain injury. Brain Injury. 26: 1629-35. PMID 22794497 DOI: 10.3109/02699052.2012.700083  0.436
2012 Schmid KE, Tortella FC. The diagnosis of traumatic brain injury on the battlefield. Frontiers in Neurology. 3: 90. PMID 22701447 DOI: 10.3389/fneur.2012.00090  0.451
2012 Papa L, Lewis LM, Silvestri S, Falk JL, Giordano P, Brophy GM, Demery JA, Liu MC, Mo J, Akinyi L, Mondello S, Schmid K, Robertson CS, Tortella FC, Hayes RL, et al. Serum levels of ubiquitin C-terminal hydrolase distinguish mild traumatic brain injury from trauma controls and are elevated in mild and moderate traumatic brain injury patients with intracranial lesions and neurosurgical intervention. The Journal of Trauma and Acute Care Surgery. 72: 1335-44. PMID 22673263 DOI: 10.1097/Ta.0B013E3182491E3D  0.397
2012 Czeiter E, Mondello S, Kovacs N, Sandor J, Gabrielli A, Schmid K, Tortella F, Wang KK, Hayes RL, Barzo P, Ezer E, Doczi T, Buki A. Brain injury biomarkers may improve the predictive power of the IMPACT outcome calculator. Journal of Neurotrauma. 29: 1770-8. PMID 22435839 DOI: 10.1089/Neu.2011.2127  0.382
2012 Mondello S, Jeromin A, Buki A, Bullock R, Czeiter E, Kovacs N, Barzo P, Schmid K, Tortella F, Wang KK, Hayes RL. Glial neuronal ratio: a novel index for differentiating injury type in patients with severe traumatic brain injury. Journal of Neurotrauma. 29: 1096-104. PMID 22165978 DOI: 10.1089/Neu.2011.2092  0.541
2012 Papa L, Lewis LM, Falk JL, Zhang Z, Silvestri S, Giordano P, Brophy GM, Demery JA, Dixit NK, Ferguson I, Liu MC, Mo J, Akinyi L, Schmid K, Mondello S, ... ... Tortella FC, et al. Elevated levels of serum glial fibrillary acidic protein breakdown products in mild and moderate traumatic brain injury are associated with intracranial lesions and neurosurgical intervention. Annals of Emergency Medicine. 59: 471-83. PMID 22071014 DOI: 10.1016/J.Annemergmed.2011.08.021  0.445
2012 Chen Z, Leung LY, Mountney A, Liao Z, Yang W, Lu XC, Dave J, Deng-Bryant Y, Wei G, Schmid K, Shear DA, Tortella FC. A novel animal model of closed-head concussive-induced mild traumatic brain injury: development, implementation, and characterization. Journal of Neurotrauma. 29: 268-80. PMID 21988140 DOI: 10.1089/Neu.2011.2057  0.522
2012 Murakami Y, Wei G, Yang X, Lu XC, Leung LY, Shear DA, Tortella FC. Brain oxygen tension monitoring following penetrating ballistic-like brain injury in rats. Journal of Neuroscience Methods. 203: 115-21. PMID 21983109 DOI: 10.1016/J.Jneumeth.2011.09.025  0.492
2012 Mondello S, Linnet A, Buki A, Robicsek S, Gabrielli A, Tepas J, Papa L, Brophy GM, Tortella F, Hayes RL, Wang KK. Clinical utility of serum levels of ubiquitin C-terminal hydrolase as a biomarker for severe traumatic brain injury. Neurosurgery. 70: 666-75. PMID 21937927 DOI: 10.1227/Neu.0B013E318236A809  0.543
2011 Wei G, Lu XC, Shear DA, Yang X, Tortella FC. Neuroprotection of Selective Brain Cooling After Penetrating Ballistic-like Brain Injury in Rats. Therapeutic Hypothermia and Temperature Management. 1: 33-42. PMID 24716886 DOI: 10.1089/Ther.2010.0007  0.461
2011 Kochanek PM, Bramlett H, Dietrich WD, Dixon CE, Hayes RL, Povlishock J, Tortella FC, Wang KK. A novel multicenter preclinical drug screening and biomarker consortium for experimental traumatic brain injury: operation brain trauma therapy. The Journal of Trauma. 71: S15-24. PMID 21795873 DOI: 10.1097/Ta.0B013E31822117Fe  0.351
2011 Mondello S, Papa L, Buki A, Bullock MR, Czeiter E, Tortella FC, Wang KK, Hayes RL. Neuronal and glial markers are differently associated with computed tomography findings and outcome in patients with severe traumatic brain injury: a case control study. Critical Care (London, England). 15: R156. PMID 21702960 DOI: 10.1186/Cc10286  0.421
2011 Shear DA, Lu XC, Pedersen R, Wei G, Chen Z, Davis A, Yao C, Dave J, Tortella FC. Severity profile of penetrating ballistic-like brain injury on neurofunctional outcome, blood-brain barrier permeability, and brain edema formation. Journal of Neurotrauma. 28: 2185-95. PMID 21644814 DOI: 10.1089/Neu.2011.1916  0.535
2011 Yao C, Wei G, Lu XC, Yang W, Tortella FC, Dave JR. Selective brain cooling in rats ameliorates intracerebral hemorrhage and edema caused by penetrating brain injury: possible involvement of heme oxygenase-1 expression. Journal of Neurotrauma. 28: 1237-45. PMID 21463155 DOI: 10.1089/neu.2010.1678  0.459
2011 Brophy GM, Mondello S, Papa L, Robicsek SA, Gabrielli A, Tepas J, Buki A, Robertson C, Tortella FC, Hayes RL, Wang KK. Biokinetic analysis of ubiquitin C-terminal hydrolase-L1 (UCH-L1) in severe traumatic brain injury patient biofluids. Journal of Neurotrauma. 28: 861-70. PMID 21309726 DOI: 10.1089/Neu.2010.1564  0.345
2011 Lu XC, Hartings JA, Si Y, Balbir A, Cao Y, Tortella FC. Electrocortical pathology in a rat model of penetrating ballistic-like brain injury. Journal of Neurotrauma. 28: 71-83. PMID 20964535 DOI: 10.1089/Neu.2010.1471  0.479
2011 Chen Z, Lu XC, Shear DA, Dave JR, Davis AR, Evangelista CA, Duffy D, Tortella FC. Synergism of human amnion-derived multipotent progenitor (AMP) cells and a collagen scaffold in promoting brain wound recovery: pre-clinical studies in an experimental model of penetrating ballistic-like brain injury. Brain Research. 1368: 71-81. PMID 20951684 DOI: 10.1016/J.Brainres.2010.10.028  0.414
2010 Manley GT, Diaz-Arrastia R, Brophy M, Engel D, Goodman C, Gwinn K, Veenstra TD, Ling G, Ottens AK, Tortella F, Hayes RL. Common data elements for traumatic brain injury: recommendations from the biospecimens and biomarkers working group. Archives of Physical Medicine and Rehabilitation. 91: 1667-72. PMID 21044710 DOI: 10.1016/J.Apmr.2010.05.018  0.442
2010 Ottens AK, Bustamante L, Golden EC, Yao C, Hayes RL, Wang KKW, Tortella FC, Dave JR. Neuroproteomics: A biochemical means to discriminate the extent and modality of brain injury Journal of Neurotrauma. 27: 1837-1852. PMID 20698760 DOI: 10.1089/Neu.2010.1374  0.471
2010 Shear DA, Lu XC, Bombard MC, Pedersen R, Chen Z, Davis A, Tortella FC. Longitudinal characterization of motor and cognitive deficits in a model of penetrating ballistic-like brain injury. Journal of Neurotrauma. 27: 1911-23. PMID 20684676 DOI: 10.1089/Neu.2010.1399  0.404
2010 Wei G, Lu XC, Yang X, Tortella FC. Intracranial pressure following penetrating ballistic-like brain injury in rats. Journal of Neurotrauma. 27: 1635-41. PMID 20568960 DOI: 10.1089/neu.2010.1378  0.459
2010 Davis AR, Shear DA, Chen Z, Lu XC, Tortella FC. A comparison of two cognitive test paradigms in a penetrating brain injury model. Journal of Neuroscience Methods. 189: 84-7. PMID 20346980 DOI: 10.1016/J.Jneumeth.2010.03.012  0.375
2010 Mondello S, Buki A, Bullock R, Robertson C, Czeiter E, Ezer E, Tortella F, Wang K, Hayes R. Brain biomarkers and brain tissue oxygenation: changes and correlations following severe head injury Critical Care. 14: 295. DOI: 10.1186/Cc8527  0.483
2009 Dave JR, Williams AJ, Yao C, Lu XC, Tortella FC. Modeling cerebral ischemia in neuroproteomics. Methods in Molecular Biology (Clifton, N.J.). 566: 25-40. PMID 20058162 DOI: 10.1007/978-1-59745-562-6_2  0.306
2009 Chen Z, Tortella FC, Dave JR, Marshall VS, Clarke DL, Sing G, Du F, Lu XC. Human amnion-derived multipotent progenitor cell treatment alleviates traumatic brain injury-induced axonal degeneration. Journal of Neurotrauma. 26: 1987-97. PMID 19886807 DOI: 10.1089/Neu.2008.0863  0.35
2009 Wei HH, Lu XC, Shear DA, Waghray A, Yao C, Tortella FC, Dave JR. NNZ-2566 treatment inhibits neuroinflammation and pro-inflammatory cytokine expression induced by experimental penetrating ballistic-like brain injury in rats. Journal of Neuroinflammation. 6: 19. PMID 19656406 DOI: 10.1186/1742-2094-6-19  0.481
2009 Lu XC, Si Y, Williams AJ, Hartings JA, Gryder D, Tortella FC. NNZ-2566, a glypromate analog, attenuates brain ischemia-induced non-convulsive seizures in rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 1924-32. PMID 19638995 DOI: 10.1038/Jcbfm.2009.109  0.327
2009 Shear DA, Williams AJ, Sharrow K, Lu XC, Tortella FC. Neuroprotective profile of dextromethorphan in an experimental model of penetrating ballistic-like brain injury. Pharmacology, Biochemistry, and Behavior. 94: 56-62. PMID 19619574 DOI: 10.1016/J.Pbb.2009.07.006  0.406
2009 Hartings JA, Strong AJ, Fabricius M, Manning A, Bhatia R, Dreier JP, Mazzeo AT, Tortella FC, Bullock MR. Spreading depolarizations and late secondary insults after traumatic brain injury. Journal of Neurotrauma. 26: 1857-66. PMID 19508156 DOI: 10.1089/Neu.2009.0961  0.341
2009 Yao C, Williams AJ, Ottens AK, Lu XCM, Liu MCh, Hayes RL, Wang KK, Tortella FC, Dave JR. P43/pro-EMAPII: a potential biomarker for discriminating traumatic versus ischemic brain injury Journal of Neurotrauma. 26: 1295-1305. PMID 19317603 DOI: 10.1089/NEU.2008.0811  0.507
2009 Lu XC, Chen RW, Yao C, Wei H, Yang X, Liao Z, Dave JR, Tortella FC. NNZ-2566, a glypromate analog, improves functional recovery and attenuates apoptosis and inflammation in a rat model of penetrating ballistic-type brain injury. Journal of Neurotrauma. 26: 141-54. PMID 19119917 DOI: 10.1089/neu.2008.0629  0.463
2008 Yao C, Williams AJ, Ottens AK, Lu XCM, Chen R, Wang KK, Hayes RL, Tortella FC, Dave JR. Detection of protein biomarkers using high-throughput immunoblotting following focal ischemic or penetrating ballistic-like brain injuries in rats Brain Injury. 22: 723-732. PMID 18720098 DOI: 10.1080/02699050802304706  0.489
2008 Hartings JA, Gugliotta M, Gilman C, Strong AJ, Tortella FC, Bullock MR. Repetitive cortical spreading depolarizations in a case of severe brain trauma. Neurological Research. 30: 876-82. PMID 18534057 DOI: 10.1179/174313208X309739  0.451
2008 Williams AJ, Tortella FC, Gryder D, Hartings JA. Topiramate reduces non-convulsive seizures after focal brain ischemia in the rat. Neuroscience Letters. 430: 7-12. PMID 18063309 DOI: 10.1016/J.Neulet.2007.09.052  0.311
2007 Williams AJ, Wei HH, Dave JR, Tortella FC. Acute and delayed neuroinflammatory response following experimental penetrating ballistic brain injury in the rat. Journal of Neuroinflammation. 4: 17. PMID 17605820 DOI: 10.1186/1742-2094-4-17  0.505
2006 Williams AJ, Hartings JA, Lu XC, Rolli ML, Tortella FC. Penetrating ballistic-like brain injury in the rat: differential time courses of hemorrhage, cell death, inflammation, and remote degeneration. Journal of Neurotrauma. 23: 1828-46. PMID 17184192 DOI: 10.1089/Neu.2006.23.1828  0.453
2006 Williams AJ, Ling GS, Tortella FC. Severity level and injury track determine outcome following a penetrating ballistic-like brain injury in the rat. Neuroscience Letters. 408: 183-8. PMID 17030434 DOI: 10.1016/j.neulet.2006.08.086  0.458
2006 Liu MC, Akle V, Zheng W, Kitlen J, O'Steen B, Larner SF, Dave JR, Tortella FC, Hayes RL, Wang KK. Extensive degradation of myelin basic protein isoforms by calpain following traumatic brain injury. Journal of Neurochemistry. 98: 700-12. PMID 16893416 DOI: 10.1111/J.1471-4159.2006.03882.X  0.398
2006 Kobeissy FH, Ottens AK, Zhang Z, Liu MC, Denslow ND, Dave JR, Tortella FC, Hayes RL, Wang KKW. Novel differential neuroproteomics analysis of traumatic brain injury in rats Molecular and Cellular Proteomics. 5: 1887-1898. PMID 16801361 DOI: 10.1074/Mcp.M600157-Mcp200  0.478
2006 Williams AJ, Bautista CC, Chen RW, Dave JR, Lu XC, Tortella FC, Hartings JA. Evaluation of gabapentin and ethosuximide for treatment of acute nonconvulsive seizures following ischemic brain injury in rats. The Journal of Pharmacology and Experimental Therapeutics. 318: 947-55. PMID 16728590 DOI: 10.1124/Jpet.106.105999  0.304
2006 Liu MC, Akle V, Zheng W, Dave JR, Tortella FC, Hayes RL, Wang KKW. Comparing calpain- and caspase-3-mediated degradation patterns in traumatic brain injury by differential proteome analysis Biochemical Journal. 394: 715-725. PMID 16351572 DOI: 10.1042/Bj20050905  0.405
2005 Wang KKW, Ottens AK, Liu MC, Lewis SB, Meegan C, Oli MW, Tortella FC, Hayes RL. Proteomic identification of biomarkers of traumatic brain injury Expert Review of Proteomics. 2: 603-614. PMID 16097892 DOI: 10.1586/14789450.2.4.603  0.416
2005 Williams AJ, Myers TM, Cohn SI, Sharrow KM, Lu XC, Tortella FC. Recovery from ischemic brain injury in the rat following a 10 h delayed injection with MLN519. Pharmacology, Biochemistry, and Behavior. 81: 182-9. PMID 15894077 DOI: 10.1016/J.Pbb.2005.03.011  0.408
2005 Williams AJ, Hartings JA, Lu XC, Rolli ML, Dave JR, Tortella FC. Characterization of a new rat model of penetrating ballistic brain injury. Journal of Neurotrauma. 22: 313-31. PMID 15716636 DOI: 10.1089/Neu.2005.22.313  0.522
2004 Williams AJ, Berti R, Dave JR, Elliot PJ, Adams J, Tortella FC. Delayed treatment of ischemia/reperfusion brain injury: extended therapeutic window with the proteosome inhibitor MLN519. Stroke; a Journal of Cerebral Circulation. 35: 1186-91. PMID 15060320 DOI: 10.1161/01.STR.0000125721.10606.dc  0.439
2004 Pike BR, Flint J, Dave JR, Lu XC, Wang KK, Tortella FC, Hayes RL. Accumulation of calpain and caspase-3 proteolytic fragments of brain-derived alphaII-spectrin in cerebral spinal fluid after middle cerebral artery occlusion in rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 24: 98-106. PMID 14688621 DOI: 10.1097/01.Wcb.0000098520.11962.37  0.417
2003 Williams AJ, Lu XC, Hartings JA, Tortella FC. Neuroprotection assessment by topographic electroencephalographic analysis: effects of a sodium channel blocker to reduce polymorphic delta activity following ischaemic brain injury in rats. Fundamental & Clinical Pharmacology. 17: 581-93. PMID 14703719 DOI: 10.1046/J.1472-8206.2003.00183.X  0.453
2003 Marin R, Williams A, Hale S, Burge B, Mense M, Bauman R, Tortella F. The effect of voluntary exercise exposure on histological and neurobehavioral outcomes after ischemic brain injury in the rat. Physiology & Behavior. 80: 167-75. PMID 14637213 DOI: 10.1016/J.Physbeh.2003.06.001  0.36
2003 Williams AJ, Hale SL, Moffett JR, Dave JR, Elliott PJ, Adams J, Tortella FC. Delayed treatment with MLN519 reduces infarction and associated neurologic deficit caused by focal ischemic brain injury in rats via antiinflammatory mechanisms involving nuclear factor-kappaB activation, gliosis, and leukocyte infiltration. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 23: 75-87. PMID 12500093  0.398
2002 Williams AJ, Ling G, McCabe RT, Tortella FC. Intrathecal CGX-1007 is neuroprotective in a rat model of focal cerebral ischemia. Neuroreport. 13: 821-4. PMID 11997694 DOI: 10.1097/00001756-200205070-00017  0.413
2002 Williams AJ, Tortella FC. Neuroprotective effects of the sodium channel blocker RS100642 and attenuation of ischemia-induced brain seizures in the rat. Brain Research. 932: 45-55. PMID 11911860 DOI: 10.1016/s0006-8993(02)02275-8  0.407
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