Joseph Edgar Darling - Publications
Affiliations: | 2010-2015 | Chemistry | Syracuse University, Syracuse, NY, United States |
| 2015-2019 | National Institutes of Health, Bethesda, MD | ||
| 2019-2021 | Frederick National Laboratory |
| Year | Citation | Score | |||
|---|---|---|---|---|---|
| 2016 | McGovern-Gooch KR, Rodrigues T, Darling JE, Sieburg MA, Abizaid A, Hougland JL. Ghrelin octanoylation is completely stabilized in biological samples by alkyl fluorophosphonates. Endocrinology. en20161657. PMID 27623288 DOI: 10.1210/En.2016-1657 | 0.486 | |||
| 2015 | Wellman MK, Patterson ZR, MacKay H, Darling JE, Mani BK, Zigman JM, Hougland JL, Abizaid A. Novel Regulator of Acylated Ghrelin, CF801, Reduces Weight Gain, Rebound Feeding after a Fast, and Adiposity in Mice. Frontiers in Endocrinology. 6: 144. PMID 26441834 DOI: 10.3389/Fendo.2015.00144 | 0.656 | |||
| 2015 | McGovern KR, Darling JE, Hougland JL. Progress in Small Molecule and Biologic Therapeutics Targeting Ghrelin Signaling. Mini Reviews in Medicinal Chemistry. PMID 26202202 DOI: 10.2174/1389557515666150722101329 | 0.691 | |||
| 2015 | Zhao F, Darling JE, Gibbs RA, Hougland JL. A new class of ghrelin O-acyltransferase inhibitors incorporating triazole-linked lipid mimetic groups. Bioorganic & Medicinal Chemistry Letters. 25: 2800-3. PMID 26009163 DOI: 10.1016/J.Bmcl.2015.05.009 | 0.609 | |||
| 2015 | Darling JE, Zhao F, Loftus RJ, Patton LM, Gibbs RA, Hougland JL. Structure-activity analysis of human ghrelin O-acyltransferase reveals chemical determinants of ghrelin selectivity and acyl group recognition. Biochemistry. 54: 1100-10. PMID 25562443 DOI: 10.1021/Bi5010359 | 0.707 | |||
| 2013 | Darling JE, Prybolsky EP, Sieburg M, Hougland JL. A fluorescent peptide substrate facilitates investigation of ghrelin recognition and acylation by ghrelin O-acyltransferase. Analytical Biochemistry. 437: 68-76. PMID 23453974 DOI: 10.1016/J.Ab.2013.02.013 | 0.719 | |||
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