| Year |
Citation |
Score |
| 2024 |
Rogers RS, Sharma R, Shah HB, Skinner OS, Guo XA, Panda A, Gupta R, Durham TJ, Shaughnessy KB, Mayers JR, Hibbert KA, Baron RM, Thompson BT, Mootha VK. Circulating N-lactoyl-amino acids and N-formyl-methionine reflect mitochondrial dysfunction and predict mortality in septic shock. Metabolomics : Official Journal of the Metabolomic Society. 20: 36. PMID 38446263 DOI: 10.1007/s11306-024-02089-z |
0.522 |
|
| 2024 |
Meisel JD, Miranda M, Skinner OS, Wiesenthal PP, Wellner SM, Jourdain AA, Ruvkun G, Mootha VK. Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism. Cell. PMID 38215760 DOI: 10.1016/j.cell.2023.12.010 |
0.525 |
|
| 2023 |
Skinner OS, Blanco-Fernández J, Goodman RP, Kawakami A, Shen H, Kemény LV, Joesch-Cohen L, Rees MG, Roth JA, Fisher DE, Mootha VK, Jourdain AA. Salvage of ribose from uridine or RNA supports glycolysis in nutrient-limited conditions. Nature Metabolism. PMID 37198474 DOI: 10.1038/s42255-023-00774-2 |
0.613 |
|
| 2022 |
Abdulaziz EN, Bell TA, Rashid B, Heacock ML, Begic T, Skinner OS, Yaseen MA, Chao LH, Mootha VK, Pierik AJ, Cracan V. A natural fusion of flavodiiron, rubredoxin, and rubredoxin oxidoreductase domains is a self-sufficient water-forming oxidase of Trichomonas vaginalis. The Journal of Biological Chemistry. 102210. PMID 35780837 DOI: 10.1016/j.jbc.2022.102210 |
0.526 |
|
| 2021 |
Jourdain AA, Begg BE, Mick E, Shah H, Calvo SE, Skinner OS, Sharma R, Blue SM, Yeo GW, Burge CB, Mootha VK. Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS. Molecular Cell. PMID 33852893 DOI: 10.1016/j.molcel.2021.02.033 |
0.535 |
|
| 2021 |
Sharma R, Reinstadler B, Engelstad K, Skinner OS, Stackowitz E, Haller RG, Clish CB, Pierce K, Walker MA, Fryer R, Oglesbee D, Mao X, Shungu DC, Khatri A, Hirano M, et al. Circulating markers of NADH-reductive stress correlate with mitochondrial disease severity. The Journal of Clinical Investigation. 131. PMID 33463549 DOI: 10.1172/JCI136055 |
0.685 |
|
| 2020 |
Rath S, Sharma R, Gupta R, Ast T, Chan C, Durham TJ, Goodman RP, Grabarek Z, Haas ME, Hung WHW, Joshi PR, Jourdain AA, Kim SH, Kotrys AV, Lam SS, ... ... Skinner OS, et al. MitoCarta3.0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations. Nucleic Acids Research. PMID 33174596 DOI: 10.1093/nar/gkaa1011 |
0.704 |
|
| 2020 |
Mick E, Titov DV, Skinner OS, Sharma R, Jourdain AA, Mootha VK. Distinct mitochondrial defects trigger the integrated stress response depending on the metabolic state of the cell. Elife. 9. PMID 32463360 DOI: 10.7554/Elife.49178 |
0.725 |
|
| 2020 |
Goodman RP, Markhard AL, Shah H, Sharma R, Skinner OS, Clish CB, Deik A, Patgiri A, Hsu YH, Masia R, Noh HL, Suk S, Goldberger O, Hirschhorn JN, Yellen G, et al. Hepatic NADH reductive stress underlies common variation in metabolic traits. Nature. PMID 32461692 DOI: 10.1038/S41586-020-2337-2 |
0.743 |
|
| 2020 |
Jain IH, Calvo SE, Markhard AL, Skinner OS, To TL, Ast T, Mootha VK. Genetic Screen for Cell Fitness in High or Low Oxygen Highlights Mitochondrial and Lipid Metabolism. Cell. PMID 32259488 DOI: 10.1016/J.Cell.2020.03.029 |
0.747 |
|
| 2020 |
Patgiri A, Skinner OS, Miyazaki Y, Schleifer G, Marutani E, Shah H, Sharma R, Goodman RP, To TL, Robert Bao X, Ichinose F, Zapol WM, Mootha VK. An engineered enzyme that targets circulating lactate to alleviate intracellular NADH:NAD imbalance. Nature Biotechnology. PMID 31932725 DOI: 10.1038/S41587-019-0377-7 |
0.751 |
|
| 2020 |
Mick E, Titov DV, Skinner OS, Sharma R, Jourdain AA, Mootha VK. Author response: Distinct mitochondrial defects trigger the integrated stress response depending on the metabolic state of the cell Elife. DOI: 10.7554/Elife.49178.Sa2 |
0.626 |
|
| 2018 |
Schleifer G, Marutani E, Ferrari M, Sharma R, Skinner O, Goldberger O, Grange RMH, Peneyra K, Malhotra R, Wepler M, Ichinose F, Bloch D, Mootha V, Zapol WM. Impaired Hypoxic Pulmonary Vasoconstriction in a Mouse Model of Leigh Syndrome. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 30520688 DOI: 10.1152/Ajplung.00419.2018 |
0.53 |
|
| 2018 |
Zheng J, Chen L, Skinner OS, Ysselstein D, Remis J, Lansbury P, Skerlj R, Mrosek M, Heunisch U, Krapp S, Charrow J, Schwake M, Kelleher NL, Silverman RB, Krainc D. β-Glucocerebrosidase modulators promote dimerization of β-glucocerebrosidase and reveal an allosteric binding site. Journal of the American Chemical Society. PMID 29676907 DOI: 10.1021/Jacs.7B13003 |
0.476 |
|
| 2018 |
Kenney GE, Dassama LMK, Pandelia ME, Gizzi AS, Martinie RJ, Gao P, DeHart CJ, Schachner LF, Skinner OS, Ro SY, Zhu X, Sadek M, Thomas PM, Almo SC, Bollinger JM, et al. The biosynthesis of methanobactin. Science (New York, N.Y.). 359: 1411-1416. PMID 29567715 DOI: 10.1126/Science.Aap9437 |
0.589 |
|
| 2017 |
Skinner OS, Haverland NA, Fornelli L, Melani RD, Do Vale LHF, Seckler HS, Doubleday PF, Schachner LF, Srzentić K, Kelleher NL, Compton PD. Top-down characterization of endogenous protein complexes with native proteomics. Nature Chemical Biology. PMID 29131144 DOI: 10.1038/Nchembio.2515 |
0.566 |
|
| 2017 |
Siegmund S, Yang H, Sharma R, Javors M, Skinner O, Mootha V, Hirano M, Schon EA. Low-dose rapamycin extends lifespan in a mouse model of mtDNA depletion syndrome. Human Molecular Genetics. PMID 28973153 DOI: 10.1093/Hmg/Ddx341 |
0.601 |
|
| 2017 |
Skinner OS, McAnally MO, Van Duyne RP, Schatz GC, Breuker K, Compton PD, Kelleher NL. Native Electron Capture Dissociation Maps to Iron-Binding Channels in Horse Spleen Ferritin. Analytical Chemistry. PMID 28938074 DOI: 10.1021/Acs.Analchem.7B01581 |
0.496 |
|
| 2017 |
Haverland NA, Skinner OS, Fellers RT, Tariq AA, Early BP, LeDuc RD, Fornelli L, Compton PD, Kelleher NL. Defining Gas-Phase Fragmentation Propensities of Intact Proteins During Native Top-Down Mass Spectrometry. Journal of the American Society For Mass Spectrometry. PMID 28374312 DOI: 10.1007/S13361-017-1635-X |
0.536 |
|
| 2017 |
Mandacaru SC, Vale LH, Vahidi S, Xiao Y, Skinner OS, Ricart CA, Kelleher NL, Sousa MV, Konermann L. Characterizing the Structure and Oligomerization of Major Royal Jelly Protein 1 (MRJP1) by Mass Spectrometry and Complementary Biophysical Tools. Biochemistry. PMID 28252287 DOI: 10.1021/Acs.Biochem.7B00020 |
0.528 |
|
| 2016 |
Skinner OS, Schachner LF, Kelleher NL. The Search Engine for Multi-Proteoform Complexes: An Online Tool for the Identification and Stoichiometry Determination of Protein Complexes. Current Protocols in Bioinformatics. 56: 13.30.1-13.30.11. PMID 27930806 DOI: 10.1002/Cpbi.16 |
0.555 |
|
| 2016 |
Melani RD, Skinner OS, Fornelli L, Domont GB, Compton PD, Kelleher NL. Mapping proteoforms and protein complexes from king cobra venom using both denaturing and native top-down proteomics. Molecular & Cellular Proteomics : McP. PMID 27178327 DOI: 10.1074/Mcp.M115.056523 |
0.566 |
|
| 2016 |
Melani RD, Seckler HS, Skinner OS, Do Vale LH, Catherman AD, Havugimana PC, Valle de Sousa M, Domont GB, Kelleher NL, Compton PD. CN-GELFrEE - Clear Native Gel-eluted Liquid Fraction Entrapment Electrophoresis. Journal of Visualized Experiments : Jove. PMID 26967310 DOI: 10.3791/53597 |
0.756 |
|
| 2016 |
Skinner OS, Havugimana PC, Haverland NA, Fornelli L, Early BP, Greer JB, Fellers RT, Durbin KR, Do Vale LH, Melani RD, Seckler HS, Nelp MT, Belov ME, Horning SR, Makarov AA, et al. An informatic framework for decoding protein complexes by top-down mass spectrometry. Nature Methods. PMID 26780093 DOI: 10.1038/Nmeth.3731 |
0.557 |
|
| 2015 |
Compton PD, Fornelli L, Kelleher NL, Skinner OS. Probing Asymmetric Charge Partitioning of Protein Oligomers during Tandem Mass Spectrometry. International Journal of Mass Spectrometry. 390: 132-136. PMID 26692813 DOI: 10.1016/J.Ijms.2015.08.021 |
0.496 |
|
| 2015 |
Skinner OS, Kelleher NL. Illuminating the dark matter of shotgun proteomics. Nature Biotechnology. 33: 717-8. PMID 26154010 DOI: 10.1038/Nbt.3287 |
0.485 |
|
| 2015 |
Savaryn JP, Skinner OS, Fornelli L, Fellers RT, Compton PD, Terhune SS, Abecassis MM, Kelleher NL. Targeted analysis of recombinant NF kappa B (RelA/p65) by denaturing and native top down mass spectrometry. Journal of Proteomics. PMID 25952688 DOI: 10.1016/J.Jprot.2015.04.025 |
0.518 |
|
| 2015 |
Durbin KR, Skinner OS, Fellers RT, Kelleher NL. Analyzing internal fragmentation of electrosprayed ubiquitin ions during beam-type collisional dissociation. Journal of the American Society For Mass Spectrometry. 26: 782-7. PMID 25716753 DOI: 10.1007/S13361-015-1078-1 |
0.487 |
|
| 2015 |
Skinner OS, Do Vale LH, Catherman AD, Havugimana PC, de Sousa MV, Compton PD, Kelleher NL. Native GELFrEE: a new separation technique for biomolecular assemblies. Analytical Chemistry. 87: 3032-8. PMID 25664979 DOI: 10.1021/Ac504678D |
0.756 |
|
| 2014 |
Ntai I, Kim K, Fellers RT, Skinner OS, Smith AD, Early BP, Savaryn JP, LeDuc RD, Thomas PM, Kelleher NL. Applying label-free quantitation to top down proteomics. Analytical Chemistry. 86: 4961-8. PMID 24807621 DOI: 10.1021/Ac500395K |
0.746 |
|
| 2014 |
Skinner OS, Catherman AD, Early BP, Thomas PM, Compton PD, Kelleher NL. Fragmentation of integral membrane proteins in the gas phase. Analytical Chemistry. 86: 4627-34. PMID 24689519 DOI: 10.1021/Ac500864W |
0.732 |
|
| 2014 |
Catherman AD, Skinner OS, Kelleher NL. Top Down proteomics: facts and perspectives. Biochemical and Biophysical Research Communications. 445: 683-93. PMID 24556311 DOI: 10.1016/J.Bbrc.2014.02.041 |
0.767 |
|
| 2013 |
Skinner OS, Breuker K, McLafferty FW. Charge site mass spectra: conformation-sensitive components of the electron capture dissociation spectrum of a protein. Journal of the American Society For Mass Spectrometry. 24: 807-10. PMID 23549668 DOI: 10.1007/S13361-013-0603-3 |
0.586 |
|
| 2012 |
Skinner OS, McLafferty FW, Breuker K. How ubiquitin unfolds after transfer into the gas phase. Journal of the American Society For Mass Spectrometry. 23: 1011-4. PMID 22476890 DOI: 10.1007/S13361-012-0370-6 |
0.563 |
|
| 2012 |
Breuker K, Skinner OS, McLafferty FW. Femtosecond laser vaporization that preserves protein-folded structure: an unproven idea. Proceedings of the National Academy of Sciences of the United States of America. 109: E206; author reply E. PMID 22307650 DOI: 10.1073/Pnas.1115475109 |
0.604 |
|
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